A Research Protocol to Evaluate the Efficacy of Powerball versus Mulligan Mobilization with Movement on Pain and Function in Patients with Lateral ...
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Journal of Pharmaceutical Research International 33(45B): 491-500, 2021; Article no.JPRI.74474 ISSN: 2456-9119 (Past name: British Journal of Pharmaceutical Research, Past ISSN: 2231-2919, NLM ID: 101631759) A Research Protocol to Evaluate the Efficacy of Powerball versus Mulligan Mobilization with Movement on Pain and Function in Patients with Lateral Epicondylitis Shivani Uttamchandani1 and Pratik Phansopkar1* 1Department of Musculoskeletal Physiotherapy, Ravi Nair Physiotherapy College, Datta Meghe Institute of Medical Sciences, Sawangi Meghe, Wardha, India. Authors’ contributions This work was carried out in collaboration between both authors. The study's design was recommended by author SU. The study was created and designed by authors SU and PP. This article's draft was written by author SU. The final text was examined and authorized for publication by authors SU and PP. Both authors read and approved the final manuscript. Article Information DOI: 10.9734/JPRI/2021/v33i45B32831 Editor(s): (1) Dr. Francisco Cruz-Sosa, Metropolitan Autonomous University, México. Reviewers: (1) Yenew Alemu Mihret, Injibara University, Ethiopia. (2) Sabah Abdellatif Hussein Ali Beza, Cairo University, Egypt. Complete Peer review History: https://www.sdiarticle4.com/review-history/74474 Received 28 July 2021 Study Protocol Accepted 04 October 2021 Published 09 October 2021 ABSTRACT Background: Amongst the most frequently repeated stress conditions within the elbow joint includes lateral epicondylitis (LE). The extensor carpi radialis brevis muscle attachment is affected mostly. The management of an individual with LE that manifests itself in repetitive upper extremity motions is the purpose of this research. There seems to be no study on the effects of PowerBall device training on the pain and function in individuals with Lateral Epicondylitis. “PowerBall device” practice is a type of strength training. Methods / Design: After conducting initial evaluations and allocation, the subjects (n=50) with LE will be involved in a randomized controlled study and classified either in an intervention group or a conventional group. The interventional group will do “PowerBall device” exercises, while others in the control group, doing MMWM. These groups will receive basic movements and ultrasound in accordance with the procedures. _____________________________________________________________________________________________________ *Corresponding author: E-mail: drpratik77@gmail.com;
Uttamchandani and Phansopkar; JPRI, 33(45B): 491-500, 2021; Article no.JPRI.74474 Discussion: The PRTEE scale measured the intervention's impact on pain and function in patients with LE, and a Hand-held Dynamometer was utilized to quantify grip strength. The findings will give considerable support for the use of the "PowerBall device" exercise and MMWM on LE patients. Conclusion: Conclusion will be drawn post study so as to see whether PowerBall device is more helpful or Mulligan Mobilization with Movement on pain and function in patients with LE. This study will give better approach to the therapist in managing the condition. Keywords: “PowerBall device”; MMWM; LE; extensor carpi radialis brevis muscle; pain & function; grip strength. ABBREVIATIONS Frequent upper - limb activities, such as computer use, dominant forearm pronation and MMWM : Mulligan mobilization with movement supination, lifting heavy, and repeated vibration, LE : Lateral Epicondylitis are perhaps the most common causes in men PRTEE: Patient Rated Tennis Elbow Evaluation and women [7]. Since this upper limb relies on RCT : Randomised Control Trial peripheral muscles, ligaments, and capsules to QOL : Quality Of Life direct action, it is frequently seen [8]. Despite its AVBRH: Acharya Vinobha Bhave Rural Hospital name, commonly found in sports such as OPD : Out-patient Department badminton, swimming, squash, baseball, and IPD : In-patient Department throwing activities. 1. INTRODUCTION Although the typical presentation of LE are obvious and simple to identify, no optimum Amongst the most common arm lesions is treatment has yet been discovered. According to Lateral Epicondylitis (LE), also known as Lateral evidence, corticosteroid injections are associated Elbow Tendinopathy (LET) or Tennis Elbow [1]. with lower results in the intermediate and long- Morris was the only one to coin the term "lawn term compared to controls [9]. Several more tennis arm" in 1882 [2]. The word tendinopathy practitioners recommend for a conservative refers to a collection of pathologies, comprising approach as the possible treatment for LE. recurrent overuse tendon conditions. This Physiotherapy is a conservative treatment option condition can affect the extensor tendons mostly for those who have LE. The exercise regimen for on lateral side of the forearm which is most LE is the most common physical therapy common in middle-aged people, with a highest rehabilitation. In general, an exercise program incidence of 40 to 60 years [3]. consists of exercises conducted in a therapy room as well as activities completed at home It's usually a job or sports-related ailment [10]. characterized by extended, consistent, repetitive eccentric contractions and wrist grasping. In the There is a higher frequency among individuals normal community, a reported incidence of 1-3 engaged in high-risk sectors involving loading, percent is found, with the dominant arm being frequent gripping, and/or wrist extension the most commonly afflicted [4]. Whereas the activities, as well as racquet sports participants name "tennis elbow" is misleading as tennis [11]. Extreme loading hastens the transition from players account for just 5 to 10% of cases, racket healthy tendons to degenerative tendinosis, sports involvement raises the risk of this issue irrespective of individual risk factors including and therefore can trigger it in 40 to 50% of age, occupation, hobbies, or previous injury [12]. athletes [5]. In addition, the impact of resistance training on Both men and women have similar rates of increasing shoulder and elbow muscular strength incidence. Approximately 75% of the people is is being investigated, although eccentric afflicted in their dominant arms, according to exercises have previously demonstrated some studies. Diagnostically and therapeutically, the relief in the symptoms of tennis elbow [13]. extensor carpi radialis brevis muscle with Recent research has discovered that vibrating episodic participation of the extensor digitorum instruments (PowerBall device) had a greater communis, extensor carpi radialis longus, and influence on muscular strength, pain, ROM, and extensor carpi ulnaris muscles is perhaps the health quality in patients with tennis elbow most commonly pulled in muscle [6]. injuries than dumbbell exercise [14]. Throughout 492
Uttamchandani and Phansopkar; JPRI, 33(45B): 491-500, 2021; Article no.JPRI.74474 the chronic stage, using a "PowerBall device" to 2. Between the ages of 20 and 50 impart extrinsic and intrinsic strain to the wrist, 3. Pain present on elbow’s lateral side elbow, and shoulder muscles is believed 4. Tenderness persists on palpation over beneficial resistance training [6]. the forearm extensor carpi radialis tendon. According to research, using the "PowerBall 5. Diagnosis confirmed on the basis of gadget" resulted in enhanced power. Despite the physical test (Cozens Test, Mill’s Test, fact that using a dynamic PowerBall has been Maudsley’s Test) demonstrated to enhance strength, function, range of motion, tennis elbow discomfort, and 2.3.2 Exclusion criteria are as follows: quality of life in overhead sportsmen, the majority of frequent concerns have yet to be validated 1. Fractures present around elbow [15]. 2. Any old surgical history around elbow Mulligan Mobilisation with movement (MMWM) is 3. Any previous pathology of bone around a kind of manual treatment that integrates elbow. continuous lateral glide with physiological elbow 4. Absence of clinical signs of tennis elbow. mobility [16]. MMWM concentrates on mobilizing 5. Any underlying deformities (Increased the joint during physiological movements, as carrying angle/ hyperextended elbow) compared to conventional mobilisation 6. Steroid injection taken recently for LE approaches that concentrate on mobilisation in a within 3 months. static posture. According to studies, MMWM is 7. Any history of acute trauma effective in reducing pain and improving the 8. Having neurological involvement. functional capacity of elbow joints in LE patients 9. Any other systemic illness like metabolic, [17]. metastatic, infective disorders. 1.1 Aim 2.4 Recruitment The purpose of this research is to see how the PowerBall Device, when compared to Mulligan The orthopaedician working under AVBRH Mobilisation with Movement, affects pain and (DMIMSU) are invited to refer the prospective function in patients with Lateral Epicondylitis. patients to our in-patient department (IPD). Patients having Lateral Epicondylitis that are 2. METHODOLOGY currently undergoing physiotherapy in the IPD will be carefully screened for research criteria. 2.1 Study Setting Once the study's eligibility requirements are fulfilled, the participants are randomly assigned Trial will be carried out in Ravi Nair to one of two groups. Approval from patients will Physiotherapy College, Musculoskeletal OPD, indeed be accumulated before the allocation and AVBRH Sawangi, Meghe, Wardha. after elaborating the purpose, nature, procedure, 2.2 Study Design and Sample Size prospective benefits and aftereffects of the intervention. The study design for patients who have been diagnosed with Lateral Epicondylitis is a single- 2.5 Procedure blinded RCT method. The total number of subjects in this experimental study is 50 (n=50). 2.5.1 Participant Timeline For three weeks, the participants would be randomly assigned to one of the two groups: an Study duration is of 1 year and intervention experimental group (Group A) and a duration is of 3 weeks so participants will be conventional group (Group B). Goals and enrolled and three weeks of intervention will be methods of the study will be informed to the completed successfully. Assessment will be done Participants before being accepted, and written on 1st day of the visit and on the 21st day i.e. patient consent form will be signed by them. completion or at the end of the intervention. 2.3 Participants 2.5.2 Implementation 2.3.1 Inclusion criteria are as follows: Randomization will be supervised by the 1. All subjects having symptoms for more research coordinator and principal investigators. than 2 weeks Participants will be asked to hand-pick a sealed 493
Uttamchandani and Phansopkar; JPRI, 33(45B): 491-500, 2021; Article no.JPRI.74474 group allocation for the recruitment into either or her shoulder and the forearm of the sufferer, group from the envelope. near to the elbow joint. While doing prolonged lateral glides with the belt, the participants are 2.5.3 Blinding told to create a fist and release it without Tester(s) will be blinded to assign the subjects to discomfort. In a single session, the therapist did the group. To ensure binding, subjects will be the technique 30 times. After ten repeats, there mandated not to reveal any details of their will be a one-minute rest time. Each session is treatment to the tester. 30-60 minutes long. Mobilizations with movement were conducted in three sets every session, five sessions planned every week for the following 3. STUDY PROCEDURE three weeks. The Exercise protocol of MMWM The individuals, divided in two groups where which will be performed is present below in the Group A would be the experimental group, and Table 2. Group B will become the conventional group. 4. OUTCOME MEASURES Prior to conducting Powerball exercises and MMWM, both Groups will always get ultrasound 4.1 Primary Outcome Measure [18] and the exercises [19]. Pulsed mode will be used for Ultrasound at 1 w/cm 2 for 10 minutes 1. Patient-Rated Tennis Elbow Evaluation using gel Binder on lateral epicondyle or at the (PRTEE) site of tenderness [20,21]. Before and after therapy, the PRTEE score is Exercises used in LE patients for pain and functional impairment assessment. The PRTEE i. Clenching the fist powerfully measure is segregated into two: pain and ii. Resisted exercises to wrist flexor and functional impairment [22]. extensor muscles. iii. Wrist pronation and supination. 2. Hand Dynamometer iv. Stretching wrist flexors and extensors for 30 Grip strength is measured using Hand held seconds at the end range dynamometer, a special clinical tool to determine and calculate the most intense Each exercise written above will be performed in isometric properties of the hand and forearm 3 series for 10 times. muscles. Dynamometers are used to measure hand strength in sports like baseball and 3.1 Group A (Experimental) tennis, where the hand is used for flipping or “PowerBall device”, utilized for this group for a lifting. strength training program that will be delivered 3. VAS for 5 sessions per week, following 3 weeks, each session lasts fora 20-64 minutes. Then frequency Visual Analogue Scale (VAS), tool used for of the "PowerBall device" will be set by total evaluating a trait or behaviour that is rounds per minute, which will range from 2000 to thought to vary across a number of values 10000, depending on the subject's capacity. and cannot be calculated directly. It is often used in observational and clinical studies to The exercise protocol of Powerball which will be assess the severity or duration of pain performed is presented below in the Table 1. while at rest or while moving. 3.2 Group B (Control Group) 4.2 Secondary Outcome Measure 1. Range of Motion In this group, Mulligan Mobilisation with movement (MMWM) will be performed in the It will be measured using the goniometer patients with LE. This is a kind of manual instrument. It will help in measuring wrist treatment wherein the participants lie in a supine and elbow movements. Subjects will be manner with their elbow extending and their assessed in sitting position as well as forearm pronated, while performing continuous supine position with full support to the lateral glides with concomitant physiological elbow. During assessment subjects should movement to the elbow joint. The clinician stays uncover the forearm and arm and should by the patient's side, wrapping the belt over his not have accessories. 494
Uttamchandani and Phansopkar; JPRI, 33(45B): 491-500, 2021; Article no.JPRI.74474 Fig. 1. Show’s the flow chart of the study 495
Uttamchandani and Phansopkar; JPRI, 33(45B): 491-500, 2021; Article no.JPRI.74474 Table 1. The Exercise protocol of PowerBall (Levels of exercise, where A - Mild, B - Moderate, C – Severe) Weeks Type of Exercise (set*time) Name of training Rest between Rest between Situation Implementation Total group sets each of Exercise duration of exercise the exercise A Exercise 1: Wrist Flexion 1 min 2 min Sitting on the table (3*30s) A Exercise 2: 2 min Sitting on the table (3*30s) Wrist Extension 1 min 1st week A Exercise 3: Elbow Flexion 1 min 2 min Standing (3*30s) 20 mins A Exercise 4: Elbow Extension Standing (3*30s) 1 min 2 min (Trunk flexion) B Exercise 1: Wrist Flexion 1min (4*45s) 30 sec 3 min Sitting on the table B Exercise 2: Wrist Extension 1min 3 min Sitting on the table (4*45s) 30 sec 2nd week B Exercise 3: Elbow Flexion 1min 3 min Standing 39 mins (4*45s) 30 sec B Exercise 4: Elbow Extension 1min 3 min Standing (4*45s) 30 sec (Trunk flexion) C Exercise 1: Wrist Flexion 2 min 4 min Sitting on the table (5*60s) C Exercise 2: Wrist Extension 2 min 4 min Sitting on the table (5*60s) 3rd week C Exercise 3: Elbow Flexion 2 min 4 min Standing 64 mins (5*60s) C Exercise 4: Elbow Extension 2 min 4 min Standing (5*60s) (Trunk flexion) 496
Uttamchandani and Phansopkar; JPRI, 33(45B): 491-500, 2021; Article no.JPRI.74474 Table 2. The Exercise protocol of MMWM Week Exercise Rest between sets Situation Implementation of Exercise Total duration (set*reps) 1st week (3*10) 1 min Sitting on the table 32 mins (5 sessions) 2nd week (3*15) 1 min Sitting on the table 47 mins (5 sessions) 3rd week (3*20) 1 min Sitting on the table 62 mins (5 sessions) 497
Uttamchandani and Phansopkar; JPRI, 33(45B): 491-500, 2021; Article no.JPRI.74474 5. DATA COLLECTION AND device and Mulligan Mobilization with movement MANAGEMENT on patients who are having tennis elbow or LE. 5.1 Data Collection 3. Student’s unpaired t-test The initial parameters variable will be used to This test is applied on the unpaired data of the obtain assessment information from a pre- independent observation made on individuals to created database. Testing data will be put into a see the difference between means of the control secure REDCap database. Paper records of and the experimental groups. evaluation forms, signed permission forms, and other data will be securely maintained in the 6. DISCUSSION research setting. Electronic information - collected from the Hand-held dynamometer in Our study aims to estimate the efficacy of DMIMSU’s electronic repository as per PowerBall device exercises compared to the participant ID. To enhance participant retention, MMWM, conventional physiotherapy on LE financial incentives will be given for attending patients' pain and function. According to Babaei- testing sessions. Additionally, the employment of Mobarakeh et al. [6] resistance training with the regular feedback concerning adherence and "PowerBall" increased grip strength, shoulders reminder phone-calls (for attending the in-person and wrists strength, performance of upper therapy) will be done. The administrator access extremity also proprioception in patients with rights will lie with the principal investigators (PI). Tennis Elbow aged 22-28 years. According to researchers, using the "PowerBall device" 5.2 Data Management resulted in enhanced power. Although it has been proven that utilizing a dynamic PowerBall The primary researchers will be in charge of improves strength, function, range of motion, collecting data and documentation. The integrity pain due to Tennis Elbow, and QOL among of the research information will be extensively overhead athletes, the bulk of common concerns examined. The Excel spreadsheet will be have yet to be verified. The primary (i.e. PRTEE released at the end of the study to an allocation index, Hand held dynamometer and VAS) and blinded statistician for conducting the necessary secondary (i.e. Range of motion) outcome analysis, following which unblinding of the groups measures will assess the efficacy PowerBall will be done. Checklists are used to prevent device exercises compared to the MMWM, missing data due to the improper staff procedure. conventional physiotherapy in Lateral epicondylitis patients pain and function. The 5.3 Statistical Analysis survey's benefits provide a customized approach to the rehabilitation protocol and the ability to The SPSS 24.0 V software will be used and adapt to the individuals' improved competencies Graph Pad Prism 7.0 V with level of significance, during the treatment. The results of the study will p
Uttamchandani and Phansopkar; JPRI, 33(45B): 491-500, 2021; Article no.JPRI.74474 There is no conflict of interest between the COMPETING INTERESTS writers and manufacturers of the goods because we do not aim to use them as a means of Authors have declared that no competing pursuing legal action, but rather to promote interests exist. knowledge. Furthermore, the study was not financed by the production business, but rather REFERENCES by the author's own efforts. 1. Stasinopoulos D, Stasinopoulou K, CONSENT Johnson M. An exercise programme for the management of lateral elbow tendinopathy. Br J Sports Med. 2005; Principal Investigators will obtain the informed 39(12):944–7. consent from the patient and one of the relatives 2. Prabhakar A, Kage V, Anap D. on a printed form with signatures and give the Effectiveness of Cyriax Physiotherapy in proof of confidentiality. Subjects with Tennis Elbow. J Nov Physiother. 2013;3. ETHICAL APPROVAL 3. Speers CJ, Bhogal GS, Collins R. Lateral elbow tendinosis: a review of diagnosis The protocol is designed after getting an and management in general practice. Br J approval from Institutional Ethics Committee of Gen Pract. 2018;68(676):548–9. Datta Meghe Institute of Medical Sciences, 4. Blanchette M-A, Normand MC. Impairment Deemed to be University. The protocol is assessment of lateral epicondylitis through designed as per the Declaration of Helsinki. The electromyography and dynamometry. J main findings concerning the efficacy of the Can Chiropr Assoc. 2011;55(2):96–106. PowerBall device exercises to enhance pain and 5. Bisset LM, Vicenzino B. Physiotherapy function will be published in a peer-reviewed management of lateral epicondylalgia. J journal and presented at an international Physiother. 2015;61(4):174–81. conference. The subjects participating in the 6. Babaei-Mobarakeh M, Letafatkar A, Barati study and the DMIMSU who will fund this AH, Khosrokiani Z. Effects of eight-week research can access the main findings of the “gyroscopic device” mediated resistance study. The data of the enrolled subjects stored training exercise on participants with securely for a minimum of 5 years. The data will impingement syndrome or tennis elbow. J be stored in the DMIMSU data repository after Bodyw Mov Ther. 2018;22(4):1013–21. the study is complete and the results are 7. Bateman M, Whitby E, Kacha S, Salt E. published Current physiotherapy practice in the management of tennis elbow: A service CONFIDENTIALITY evaluation. Musculoskeletal Care. 2018; 16(2):322–6. 8. Aqeel Ahmed, Muhammad Ibrar, Aatik The study program will be explained to the Arsh, Sonia Wali, Shoukat Hayat, Summar participant and one of his/her relative, and the Abass. Comparing the effectiveness of principal investigator will take personal mulligan mobilization versus cyriax information. The consent form will include the approach in the management of patients confidentiality statement and signatures of the with subacute lateral epicondylitis. J Pak principal investigator, patient and 2 witnesses. If Med Assoc. 2020;1–11. required to disclose some information for the 9. Lee J, Kim T, Lim K. Effects of eccentric study, consent will be taken from the patient with control exercise for wrist extensor and complete assurance of his confidentiality. shoulder stabilization exercise on the pain and functions of tennis elbow. J Phys Ther FUNDING Sci. 2018;30(4):590–4. 10. Pienimäki TT, Tarvainen TK, Siira PT, No direct support will be taken for funding this Vanharanta H. Progressive Strengthening research from any public and private and Stretching Exercises and Ultrasound organizations. The Department of Physiotherapy for Chronic Lateral Epicondylitis. under Datta Meghe Institute of Medical Sciences, Physiotherapy. 1996;82(9):522–30. Deemed to be University, will provide the 11. Balan SA, Garcia-Elias M. Utility of the necessary material for the research. Powerball in the invigoration of the 499
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