Biennial Report 2017 & 2018 Cochrane Switzerland - Trusted evidence Informed decisions Better health

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Biennial Report 2017 & 2018 Cochrane Switzerland - Trusted evidence Informed decisions Better health
Biennial Report
2017 & 2018
Cochrane Switzerland

Trusted evidence
Informed decisions
Better health
Biennial Report 2017 & 2018 Cochrane Switzerland - Trusted evidence Informed decisions Better health
Biennial Report 2017 & 2018                                                                2

Contents
Foreword                                                                                  3
1. Key activities                                                                         4
1.1.   Producing evidence                                                                 4
1.2.   Making evidence available                                                           7
1.3.   Advocating for evidence                                                            9
1.4. Developing the organisation                                                         13
2. Our team                                                                              18
3. Key financial data                                                                    20
Annex 1 - Peer reviewed articles by our team in 2017 and 2018                            21
Annex 2 - Cochrane reviews newly published or updated in 2017/2018 involving authors based
in Switzerland                                                                            27
Annex 3 - Access to Cochrane Library in Switzerland, 2015-2018                           31
Annex 4 - Other publications by Cochrane Switzerland, 2017 / 2018                        32
Annex 5 – Cochrane blogposts in the blog “Wissen was wirkt”                              36
Biennial Report 2017 & 2018 Cochrane Switzerland - Trusted evidence Informed decisions Better health
Biennial Report 2017 & 2018                                                                      3

Foreword
“The only thing that is constant is change” - this sentence commonly ascribed to Heraclitus
encapsulates quite well the past two years in and around Cochrane Switzerland. In this Biennial
Report for the years 2017 and 2018 we describe our activities in the domains outlined in our
Strategic Plan. During this time the institutional set-up around us but also the composition of our
own team saw some important changes:

In early 2017, it became clear that our host institution, the Institute for Social and Preventive
Medicine (IUMSP) would undergo a radical transformation. It was decided to dissolve the whole
department of the Lausanne University Hospital, of which IUMSP was a part, and to form a new
academic centre, the Centre for Primary Care and Public Health (Unisanté) as a merger of several
institutes of the Canton of Vaud with similar missions. Now, two years later, a transition period
comes to a close that was marked by some uncertainties and we look forward to the future work
within the new set-up. What remained certain were our current premises – you still find us on the
Biopôle campus in Lausanne and in the House of the Academies in Berne.

In summer 2018, another important change took place when Bernard Burnand retired as director
of Cochrane Switzerland. In the past two years, I was grateful not only to Bernard for his
longstanding involvement but also to our team for their flexibility and commitment, for instance
when taking on additional tasks during the prolonged absence of our coordinator. I was honoured
to have been appointed as the new director by Cochrane’s leadership and (as co-director at this
time) to have been elected as representative of the Cochrane Centres in the newly created
Cochrane Council in 2017.

During the reporting period, we continued to support the production of numerous Cochrane
reviews in Switzerland in different ways from answering a quick technical question to substantial
involvement as co-authors. Regarding our own reviews, a highlight was the updated methods
review “Full publication of results initially presented in meeting abstracts” published in November
2018 together with co-authors from Germany and the USA. It now includes no less than 425 studies.
In line with Cochrane’s new Knowledge Translation Strategy, we have put quite some emphasis on
activities to make Cochrane evidence known in Switzerland. The continued country-wide free
access to the Cochrane Library has been critical for these efforts; we hope it can be renewed after
2020. With the German-speaking evidence users in mind, we contributed blog posts to the
Cochrane blog “Wissen was wirkt” and attracted competitive funding to translate plain language
summaries for “Cochrane Kompakt”. Both are joint projects together with our colleagues in
Germany and Austria. Our efforts in capacity building were marked by a new two-week workshop
that we developed together with the WHO HRP Alliance for mid-career researchers from low- and
middle-income countries and carried out in autumn 2017 and 2018.

The following pages will give you a much more detailed overview of all these activities. We are
curious to know about your feedback, suggestions and questions – stay in touch!

Erik von Elm, MD MSc
Director Cochrane Switzerland
Biennial Report 2017 & 2018 Cochrane Switzerland - Trusted evidence Informed decisions Better health
Biennial Report 2017 & 2018                                                                          4

1. Key activities
Our activities during the past two years were aligned with the four main
objectives in Cochrane’s “Strategy to 2020”: producing evidence, making
evidence available, advocating for evidence and developing the organization.
Our own strategic plan is consistent with this broader strategy while adjusting
it to the healthcare setting in Switzerland and the resources available to our
Associate Centre.

1.1. Producing evidence

1.1.1 Courses and workshops
Cochrane Switzerland provides a number of training opportunities during the year. These are
courses and workshops at introductory level aiming to increasing awareness and interest in using
or conducting systematic reviews and more advanced workshops aiming to strengthen
methodological and statistical capacity of current and new review authors.

In 2017 and 2018, we organised or contributed to in the following training events:

    Introductory course for Cochrane review authors (March 2018): This three-day course was
    organised jointly with Cochrane Germany and Cochrane Austria and, this time, held in Freiburg
    / Germany. A total of 32 participants took part. They learned the basic concepts and skills that
    are needed to conduct a Cochrane intervention review. The course addressed topics such as the
    definition of the review question, protocol development, systematic literature searches in
    electronic databases, selection of studies, risk of bias evaluation, data extraction, meta-analysis
    and interpretation of findings. It also introduced participants to Cochrane’s software Review
    Manager and the GRADE framework. In the previous year, the course could not be held due to
    the small number of registrations.

    Meta-analysis: advanced methods using STATA (September 2017 and 2018): This 2.5-day
    course was attended by about 12 participants in both years; most of them with a background in
    medical statistics or systematic reviews. The course was held by our statistician Patrick Taffé
    and tackled the theoretical foundation and techniques needed to carry out meta-analyses using
    the STATA software. It was preceded by an optional one-day refresher for the use of the
    statistical package STATA.

    IUMSP & WHO HRP Alliance research methods training course (September/October 2017
    and November 2018): With a mandate by the WHO Human Reproduction Programme (HRP)
    Alliance we organised a two-week course, jointly with the IUMSP unit for qualitative research.
    Together with the WHO HRP team we developed a course curriculum with the overarching
    perspective of implementation research. In the first week, the focus was on the skills needed to
    conduct systematic reviews, and during the second week on methods of qualitative research.
Biennial Report 2017 & 2018 Cochrane Switzerland - Trusted evidence Informed decisions Better health
Biennial Report 2017 & 2018                                                                         5

    Cochrane Switzerland was in charge of the content of the first course week. The training was
    specifically developed for mid-career researchers in sexual and reproductive health from low-
    income countries, where such training opportunities are not available. Participants were
    identified through the partner institutions of the HRP Alliance in the participating countries. In
    both years, the course was attended by a very diverse group of about 20 participants, many of
    whom travelled to Switzerland or even Europe for the first time. The programme included time
    to interact with staff of the WHO HRP Alliance during the course and a full-day visit to the WHO
    headquarters in Geneva.

    SSPH+ Symposium “How to improve the use of evidence-based health (care) information
    in practice and policy? The role of rapid reviews and policy briefs, and their synergistic
    effects” (November 2018): The two-day symposium was jointly organised together with
    IUMSP and the University of Lucerne and supported by the Swiss School of Public Health
    SSPH+. On the first day, it included plenary presentations by two international speakers and
    small group discussions on ways to produce high-quality evidence on specific health (care)
    issues in a timely and suitable manner. The second day was devoted to a short course about the
    conduct of rapid reviews delivered by members of the Cochrane Rapid Reviews Methods Group.
    Both days were fully booked with about 48 participants on Day 1 and 33 participants on Day 2.

Our team was also involved in under- and postgraduate teaching on methods of evidence-based
medicine at Swiss universities and applied universities as well as academic institutions abroad. In
2017 and 2018 these training events included:

    Introductory module on clinical research methods (February 2017 and 2018): Under-
    graduate teaching of 3rd year medical students, Faculty of Biology and Medicine, University of
    Lausanne.

    Certificate of Advanced Studies (CAS) in Clinical Research Methods (December / February
    2017 and 2018): Lectures about systematic reviews in the curriculum organised by IUMSP as
    well as in the optional module “Systematic Reviews and Meta-analyses” organised by the
    Clinical Epidemiology Unit in the curriculum of the Faculty of Medicine at University of Geneva.

    Cochrane systematic reviews & critical appraisal (November 2018): Full-day seminar in
    advanced module “Evidence-based Medicine” of the Master of Advanced Studies (MAS) in
    Insurance Medicine, University of Basel.

    Seminar and journal club on reporting guidelines (March 2017 and 2018): Half-day course in
    the curriculum of the European Master of Science in Epidemiology at the Institute for Medical
    Biometry, Epidemiology and Informatics (IMBEI) at the University of Mainz, Germany.

    Lecture about Cochrane Crowd (August 2018): 6th Symposium of Swiss medical librarians
    supporting research, education and clinical practice (“Meet & Greet”) at University of Bern.

    Lecture about the national provision for the Cochrane Library (September 2017):
    Introductory day about electronic resources (eDay) of the Medical Library
    (Fachbereichsbibliothek Bühlplatz) at University of Bern.
Biennial Report 2017 & 2018                                                                        6

1.1.2 Systematic review projects
In 2017 and 2018, we worked on several systematic review projects. See Annex 1 for the full
references of projects published during these two years.

    In July 2017, team members published the first update of the Cochrane review titled
    “Computer‐generated reminders delivered on paper to healthcare professionals: effects on
    professional practice and healthcare outcomes”. It is hosted by the review group Cochrane
    Effective Practice and Organization of Care (EPOC) and now includes 30 randomized trials and
    five non‐randomized trials.

    Together with co-authors in the USA and Germany we completed the first update of our
    Cochrane review titled “Full publication of results initially presented in abstracts” in November
    2018. This comprehensive methodology review now includes 425 studies (described in 551
    articles) on the subsequent full publication of a total of 307,028 meeting abstracts from the
    biomedical and social sciences. The review provides robust evidence for the persistent
    underreporting of health research projects and underpins the international efforts to tackle the
    problem of research waste.

    Work on the Cochrane review protocol “Interventions implemented through sporting
    organisations for promoting healthy behaviour or improving health outcomes” has progressed
    but was slower than expected because two contributing co-authors changed jobs during the
    reporting period. We plan to update the literature search and include additional studies (if any)
    in 2019.

    Our ongoing review titled “Factors that influence women’s engagement with breastfeeding
    support: a qualitative evidence synthesis” has reached the stage of a published protocol in
    November 2018. This review project with the Consumer and Communication Review Group is
    led by our former collaborator Theresa Bengough. It is part of her ongoing PhD thesis with the
    Social Research Methodology Group at the Faculty of Social Sciences, University of Leuven,
    Belgium, and will complement three existing Cochrane intervention reviews on the support for
    breastfeeding mothers. To tackle the anticipated workload with this review, several co-authors
    from the UK are now involved in the project. The screening of the retrieved literature could be
    completed meanwhile, and work on critical appraisal of included studies and data extraction
    will begin in 2019.

    Our team member Muaamar Al-Gobari has completed his PhD thesis and graduated on 19th
    July 2018. His thesis project to systematically review current therapeutic strategies for sudden
    cardiac death prevention in heart failure patients has resulted in two publications, in PLoS One
    in 2017 and in BMJ Open in 2018.

1.1.3 Contributions to Cochrane review production
As part of our overall goal to promote Cochrane review production, we supported several
systematic review projects that were led by author groups in Switzerland and abroad, either as co-
authors, editors, methods advisors or referees. These reviews were hosted by the following Review
Groups:
   • Tobacco Addiction Group;
Biennial Report 2017 & 2018                                                                       7

   •   Drugs and Alcohol Group;
   •   Effective Practice and Organisation of Care Group;
   •   Injuries Group;
   •   Methods Group;
   •   Cochrane Work Group;
   •   Upper GI and Pancreatic Diseases Group;
   •   Consumers and Communication Group.

A full list of Cochrane Reviews published by author teams based in Switzerland is provided in
Annex 2.

1.2. Making evidence available
The full content of the Cochrane Library with about 8000 systematic reviews is available in English
but not in the three Swiss national languages. Many healthcare professionals in the country access
and read health information in English but prefer if it is written in their own language. Other user
groups including patients and consumers groups, the media, and policy makers have a strong
preference for content in the national languages. Consequently, we maintain versions of our
website in French, German, Italian and English. In 2017 and 2018 we also produced new information
material to draw attention to Cochrane resources. We created this material with the support of
Cochrane’s Central Executive Team and the publisher of the Cochrane Library, Wiley & Sons (UK).
The flyers are available on our website for download and printing and were distributed at several
events.

1.2.1 Cochrane Library national provision

Since 2016, Swiss residents have free and unrestricted access to the full content of the Cochrane
Library through one-click access. This has been made possible by the continued commitment of the
Swiss Academy of Medical Sciences (SAMS), the Federal Office of Public Health and the academic
medical libraries with the aim to grant health professionals and the public access to a high-quality
source of health information that is free from commercial interests. The current national license
agreement is for the period 2016-2020. During 2017 and 2018 we have worked with SAMW and
Biennial Report 2017 & 2018                                                                         8

several libraries to raise awareness and promote the use of the Cochrane Library and will continue
to do so.

We are monitoring the user statistics for download of pdf-files or access to HTML full versions of
Cochrane reviews on a quarterly basis. Access numbers remained stable during the past two years
with about 163’000 full text reviews downloaded per year. Usage followed a seasonal pattern with
peaks in spring and October/November (see graph in Annex 3). In the last quarter of 2018
Switzerland recorded the fifth highest number of full text accesses compared to other countries
with a national provision for the Cochrane Library.
The joint effort of the three Cochrane Centres in the German-speaking countries for translation of
the plain language summaries (Cochrane Kompakt, see Section 1.2.3) as well as the availability of such
translations in French through Cochrane France further supports our efforts to make the Cochrane
Library known in Switzerland.

1.2.2 Publications in medical education journals

We continued our partnerships with three medical education journals in Switzerland and one in
France to provide tailored information to selected professional groups:

    physioactive: This bi-monthly journal is published by the professional organization of
    physiotherapists in Switzerland physioswiss. As guest editors, we edit a series of articles about
    Cochrane reviews of interest to physiotherapists that are selected by two collaborating
    physiotherapists. In 2017, physioactive featured five such summaries, and in 2018 four.

    Ars Medici: This new collaboration with a bi-weekly journal for primary care practitioners has
    been started with a published interview with Erik von Elm in July 2017. Since then, ars medici
    has published several short articles on recent Cochrane reviews under the heading "Neues aus
    der Cochrane Library". In 2017, two summaries were published and in 2018 sixteen. For some
    articles, a clinical specialist was invited to comment on the findings of the Cochrane review.

    Tribuna Medica Ticinese: This monthly bulletin caters to health professionals in the canton of
    Ticino, the Italian speaking part of Switzerland. In 2017, four summaries were published in
    Tribuna Medica Ticinese, and in 2018 three.

    Médecine & Enfance: In 2018, we published one summary in the column “Coté Cochrane” of
    this French specialist journal for pediatricians.

See Annex 4 for a full list of references to articles from 2017 and 2018 featuring Cochrane evidence
in these medical education journals.

1.2.3 Cochrane Kompakt - Cochrane summaries in German

We continued our active collaboration with Cochrane Germany for Cochrane Kompakt
(www.cochrane.org/de/kompakt). This resource includes German translations of plain language
summaries of Cochrane Reviews and was initiated in 2014. The focus is on recently published or
updated reviews and those in selected fields of interest, for which collaborations with professional
societies could be established. As of December 2018, more than 1500 German-language
summaries were published in Cochrane Kompakt. In 2017 and 2018, this activity was made possible
Biennial Report 2017 & 2018                                                                       9

with funding from the SANA Foundation (Bern, Switzerland). Following a joint proposal together
with the Institute of Midwifery at the Zürich University of Applied Sciences (Zürcher Hochschule
für Angewandte Wissenschaften - ZHAW) we received a grant allowing us to translate a total of 120
plain language summaries in the area of pregnancy and childbirth. ZHAW offers Master studies for
specialised professional translators. Our joint project has enabled a collaboration that is now
continuing with translation of Cochrane Kompakt content on a regular basis. A second grant from
the SANA Foundation has received a positive response in December 2018 and will support the
translation of 150 more plain language summaries in the area of nutrition and health in 2019.

1.2.4 “Wissen Was Wirkt” - The Cochrane blog in German

The blog “Wissen Was Wirkt – Cochrane bloggt auf deutsch” (www.wissenwaswirkt.org) is another
key collaboration with our colleagues in Germany and Austria. The blog highlights recently
published Cochrane reviews, in particular those with plain language summaries already translated
into German while increasing the visibility of Cochrane Kompakt. In addition, it covers other topics
or events about evidence-based healthcare that are of interest to the blog’s readership. In 2017 and
2018, the blog has become more prominent and popular. Below are some highlights and key
numbers from 2017 and 2018:

    A total of 82 blog posts were published during this two-year period. Our team contributed four
    articles in 2017 and six in 2018. A list of the titles is provided in Annex 5.

    The blog had about 3300 visits per month in 2018 according to Google Analytics.

    The content is also actively disseminated via a Facebook page with more than 800 followers and
    a Twitter account with more than 1000 followers.

    In response to the blogposts, we usually receive only few comments. In some of them readers
    ask for more information or give us general feedback such as the following:

    “I read several good stuff here. Certainly worth bookmarking for revisiting. I wonder how much
    effort you put to create such a fantastic informative website.” (June 2018)

1.3. Advocating for evidence
New information material specific for Cochrane Switzerland has been developed and disseminated
during 2017 and 2018 at several events. We created this material with the support of Cochrane’s
central executive team and the publisher of the Cochrane Library, Wiley & Sons (UK). For instance,
our flyers highlighted the national provision (see section 1.2), Cochrane Kompakt, or the work of
Cochrane Public Health Europe.

1.3.1 Work with the media

Our team members were spokespersons for healthcare-related themes in the media or provided
background information to journalists on several occasions. The following are examples of
activities involving Swiss media:
Biennial Report 2017 & 2018                                                                       10

    Interview, RTS 1 channel, CQFD programme (October 2017): Many anti-cancer treatments
    are licensed without providing benefits in terms of quality of life. According to a study by the
    King's College and the London School of Economics and Political Science that was published in
    the BMJ, 57% of anti-cancer treatments are launched without demonstrating that they increase
    patients’ survival or quality of life. Bernard Burnand commented on this study in an interview in
    the popular health programme CQFD in the French-speaking radio channel RTS 1.

    Interview, RTS 1 channel, CQFD programme (February 2018): Bernard Burnand was invited
    to join Matthias Egger in the French-speaking radio channel RTS 1 to talk about a new network
    meta-analysis on the effectiveness of 21 anti-depressants, that was published in The Lancet by
    a large consortium including Swiss researchers.

    “Eco Santé” column in Tribune de Genève: In 2017, we were invited to write two short articles
    in the column "Eco Santé" of Tribune de Genève, one of the newspapers in the canton of
    Geneva. The topics covered were: "Décider pour sa santé en utilisant des preuves fiables"
    (Making decisions for health using reliable evidence) and "L'Echinacée, un remède naturel
    efficace pour soigner le rhume? " (Echinacea, an effective natural medication to treat common
    cold).

    Press releases in German, French and Italian: In 2017, two press releases issued by Cochrane
    were translated in German, French and Italian. Both were highlighting new Cochrane reviews
    on “Tobacco packaging design for reducing tobacco use” and “Support for health professionals
    reduces unnecessary use of antibiotics in hospitals”. In 2018, the press release accompanying
    the Cochrane Review “Prophylactic vaccination against human papillomaviruses to prevent
    cervical cancer and its precursors” and the review’s plain language summary were translated in
    German on very short notice at the time of publication. This review received considerable
    attention in the media in Switzerland and is among the ten most downloaded Cochrane reviews
    in the country. Another press release of 2018 was on a new Cochrane review titled “Omega‐3
    fatty acid addition during pregnancy”. Our translated press release was picked up by the Swiss
    television SRF in their health programme “Puls” in November 2018
    (www.srf.ch/sendungen/puls/omega-3-fettsaeuren-reduzieren-fruehgeburten).

1.3.2 Work with consumer organizations

In 2017, we completed a collaborative project with the “Fédération Romande des Consommateurs”
(FRC), the leading consumer organization in the French-speaking part of Switzerland. This project
aimed at strengthening the exchange between healthcare consumers and professionals by
involving them in dialogues. This activity is now continued by FRC under the headline “Tous
consomm’acteurs de la santé” (We are all consumer/actors in healthcare)
(www.frc.ch/dossiers/tous-consommacteurs-de-la-sante).

We also piloted an online resource that highlights Cochrane evidence on selected topics of
relevance to the general public. In an electronic survey this format received positive feedback and
we plan to integrate it into a new information platform in the future. The collaborative project
received funding from the health promotion fund of the Canton of Vaud, the “Commission de
prévention de la santé et de lutte contre les addictions” (CPLSA).
Biennial Report 2017 & 2018                                                                        11

1.3.3 Work with professional groups

    Cochrane Public Health Europe (CPHE) is the European satellite of the Cochrane Public Health
    (CPH) review group (http://ph.cochrane.org). In August 2018, the editorial base of Cochrane
    Public Health was transferred from Melbourne to Newcastle, Australia, when the leadership of
    the review group changed. The new joint coordinating editors are Luke Wolfenden (University
    of Newcastle, Australia) and Hilary Thomson (University of Glasgow, UK). We continued to
    contribute to the activities of CPHE within our established network of five centers in Germany,
    Austria and Switzerland. We promoted the uptake of CPH evidence through emails to selected
    stakeholders in Swiss public health institutions at the time when new public health reviews of
    interest were published, and supported the review production at the editorial stage of several
    reviews.

    Since late 2017, a major activity of CPHE was the preparation of grant proposal for a so-called
    “Research unit” (Forschergruppe) of the German Research Foundation (DFG). Under the lead
    of our colleagues at the Ludwig-Maximilians-University Munich, Germany, an interdisciplinary
    consortium with additional partners was convened. The proposed collaborative group plans to
    carry out seven sub-projects over a period of six years with the aim to develop a new model of
    evidence-informed public health that actively involves public health practitioners in the co-
    production of evidence. The overall proposal includes one sub-project in Austria and one in
    Switzerland (co-led by Zurich and Lausanne). The overall proposal was selected by the DFG
    panel in charge in the first round in 2018 and will be presented in a final round in spring 2019.

    Swiss Medical Board (SMB): As a permanent mandate we continued to be in charge of the
    Scientific Secretariat that supports the SMB Appraisal Committee in its role as an independent
    expert panel. We were involved in the production of two SMB Appraisal Reports on (1)
    combined drug therapy for moderate to severe Alzheimer's disease and (2) on robot-assisted
    surgery for prostatectomy and hysterectomy, as well as the scoping of several upcoming HTA
    projects that the SMB will take on. The most recent SMB report used two Cochrane reviews as
    the basis to assess the clinical effectiveness and safety of robot-assisted surgery interventions.
    In this context, we piloted the integration of a Cochrane Targeted Update of a Cochrane review
    last updated in December 2014 as a mandate to the Cochrane Response team in London, UK.
    This collaboration turned out to be a successful model for the use Cochrane evidence in the
    context of HTA. Upon completion, Peter Suter, past president of SMB, commented:

    "Our experience with them has been very positive. All the timelines were met and the
    communication with the Cochrane Response team has been effective. We would highly
    recommend this service, in particular if timelines are tight."

    Federal Office of Public Health & swissethics: During the year 2018 we were part of a
    consortium led by the Swiss Clinical Trials Organization (SCTO) together with researchers of
    ceb Basel and the Clinical Trials Unit Basel. Within this consortium we took on a mandate by
    the Federal Office of Public Health (FOPH) for one project to evaluate the new Human Research
    Act that came into effect in 2014. Together with researchers of the ESOPE team at our host
    institute, we designed, implemented and conducted an online survey of more than 2000
    investigators who had submitted a study protocol for approval by a Cantonal research ethics
    committee in 2017. This survey represents a key component of this evaluation and will inform
    potential adjustments of the current regulation based on the experience gathered during the
Biennial Report 2017 & 2018                                                                            12

    first few years since introduction of the law. The final reports of all three project parts as well as
    a summary have been published online by FOPH on their website (https://bit.ly/2WoJtuT).

    Swiss Academy of Medical Sciences (SAMS): In 2018 we carried out an evidence synthesis in
    the context of the revision of the SAMS guidance document on decisions about resuscitation
    (SAMW Richtlinien Reanimationsentscheidungen). We identified the evidence from systematic
    reviews on potential prognostic factors at time of cardiopulmonary resuscitation in children and
    adults in both the in-hospital and out-of-hospital setting, assessed the methodological quality
    of the included 21 reviews and summarized the evidence in a report. In December 2018, results
    were presented to the SAMS subcommittee in charge. It is planned to publish the data in a peer-
    reviewed journal in 2019.

1.3.4 Presentations at scientific meetings

Our team participated in several national and international conferences in 2017 and 2018 with oral
and poster presentations. These included:

    Annual Conference of the German Network for Evidence-based medicine (Hamburg,
    Germany; 9-11 March 2017): We held a workshop titled “Cochrane für alle – Übersetzungen
    und Verbreitung von Cochrane-Evidenz auf Deutsch“. We also had a talk in the series
    „Methodik“ and participated in the working group meeting of Cochrane Public Health Europe.

    Global Evidence Summit (Cape Town, South Africa; 13-16 September 2017): We presented
    results of our evaluation of the text mining tool RobotAnalyst® firstly in an oral presentation
    titled “Using the RobotAnalyst text-mining application to boost efficiency of literature
    screening: experience from a systematic review in health services research”” and secondly as
    part of a joint workshop together with the RobotAnalyst developers from the National Center
    for Text Mining, University of Manchester, UK. This collaboration has resulted in a joint
    publication titled “Prioritising references for systematic reviews with RobotAnalyst: A user
    study” in the journal Research Synthesis Methods in June 2018. At the conference we were also
    actively involved in meetings of several Cochrane working / strategic groups including those of
    the Centre Directors, the Cochrane Council, the Translation Advisory Group, and the Cochrane
    Public Health Group.

    Annual Conference of the German Network for Evidence-based medicine (Graz, Austria; 8-
    10 March 2018): We co-organised a workshop on “Cochrane - Evidenz für alle und zum
    Mitmachen!” and a stand of the three German-speaking Cochrane Centres. We also
    participated in the working group meeting of Cochrane Public Health Europe.

    Cochrane Colloquium (Edinburgh, Scotland, 16-18 September 2018): We attended the
    meetings of several Cochrane groups including those of the directors of the Cochrane Centres,
    the Cochrane Council, the Translation Advisory Group. Together with our colleagues of
    Cochrane Germany, we presented the knowledge translation project “Cochrane Kompakt” as a
    poster.

    Swiss Public Health Conference (Basel, 22-23 November 2017): Together with partners from
    EBPI Zürich we organised a workshop to present and discuss a newly developed short format
Biennial Report 2017 & 2018                                                                    13

    for evidence from public health reviews. This format has been developed in the Cochrane Public
    Health Europe network earlier and has been described with a worked example in the journal
    Research Policy and Systems (July 2018) in an article titled “Facilitating evidence uptake:
    development and user testing of a systematic review summary format to inform public health
    decision-making in German-speaking countries”.

    Swiss Public Health Conference (Neuchâtel, 7-8 November 2018): We convened a workshop to
    promote the uptake of Cochrane’s citizen science platform Cochrane Crowd. The group of
    participants was introduced to the RCT/CCT identification task in Cochrane Crowd and
    competed in a live challenge in two teams. This interactive workshop format allowed them to
    discover this interactive way of contributing to Cochrane’s work with small tasks.

1.4. Developing the organisation
Team members contributed to the development of Cochrane as an international organization
through their involvement in several working groups. This included representation of the Cochrane
Centres as elected member of the Cochrane Council, co-chairing the Centre Directors Executive,
and membership in the WHO Cochrane Working Group and the Translation Advisory Group. In May
2017 and 2018, Erik von Elm was a member of Cochrane's delegation at the 70th and 71st World
Health Assembly in Geneva. Cochrane has a non-voting observer status as an accredited civil
society organization in this meeting.
Biennial Report 2017 & 2018                                                                                         14

1.4.1 Our strategy
The Strategic Plan 2015-20201 of Cochrane Switzerland defines four goals and nine objectives, that
continued to guide our work in the years 2017 and 2018:

Goal 1:         Provide training in systematic reviews, and contribute to Cochrane Reviews and
                development of review methodology.
Objective 1.1   Train researchers, healthcare professionals and other interested groups in the principles and
                methodology of systematic reviews. We aim to capacitate and motivate people to contribute to
                reviews in their discipline and thus increase the number of contributors residing in Switzerland.
Objective 1.2   Carry out systematic reviews on Swiss priority healthcare concerns. Our team is already involved in
                conducting systematic reviews. Targeting these reviews to Swiss healthcare priorities will facilitate
                awareness-raising for evidence-informed decision making.
Objective 1.3   Contribute to the further development of Cochrane methodologies, especially in the areas of public
                health, and in the organisation and delivery of effective healthcare practices. Cochrane Switzerland
                aims to continue its active involvement in the European Satellite of the Cochrane Public Health Group
                and in the Cochrane Effective Practice and Organisation of Care Group (EPOC).

Goal 2:         Increase the use of evidence in healthcare by making it accessible to key actors
                of the Swiss health system.
Objective 2.1   Make Cochrane evidence accessible in the three national languages of Switzerland (French, German,
                Italian). Until recently, most of the Cochrane evidence was available in English only. For consumer
                and patient groups, the general public, but also for many health practitioners, the language
                represents a barrier to access and use of scientific evidence. Cochrane, in its Strategy to 2020,
                acknowledges the urgency to address language needs and identifies a number of targets to increase
                access through multi-lingual content. Cochrane Switzerland will build on these activities and
                implement additional activities where needed to address the language needs of Swiss stakeholders.
Objective 2.2   Respond to user needs and align communication formats and channels to these needs. This objective
                complements Objective 2.1 but emphasises increasing access by using various communication
                approaches.
Objective 2.3   Liaise with media to raise awareness of the available evidence and resources. Media in Switzerland
                (as well as elsewhere) report almost daily on new diagnostic tests or treatments. It is often not clear
                what evidence is used in these reports and how trustworthy this evidence is. With this objective, we
                aim to increase the use of evidence by the media in their reporting on health issues.

Goal 3:         Advocate for evidence and make Cochrane’s work known in Switzerland.
Objective 3.1   Advocate for evidence-informed healthcare decision making, and for Cochrane and its resources as
                the ‘home of evidence’. We acknowledge that decision making is influenced by many factors at
                national and cantonal levels, but focus our approach on how evidence can be accessed and used so
                that it can start playing a larger role in decision making.

Goal 4:         Build an effective and sustainable structure for Cochrane Switzerland to carry
                out its work.
Objective 4.1   Develop Cochrane Switzerland into a sustainable structure serving the needs of patients and
                healthcare professionals in Switzerland. This objective focuses on developing a process and structure
                that facilitates the participation of stakeholders in the work of Cochrane Switzerland.
Objective 4.2   Actively contribute to the international activities of Cochrane, especially through the various
                Cochrane Review Groups and the Cochrane Fields.

1
 Cochrane Switzerland. Strategic Plan 2015-2020. Available from:
http://swiss.cochrane.org/sites/swiss.cochrane.org/files/uploads/pdf/Strategic%20plan%202015-2020.pdf
Biennial Report 2017 & 2018                                                                     15

1.4.2 Partnerships and involvement in professional groups
Cochrane Switzerland has been hosted by the Institute of Social and Preventive Medicine (IUMSP)
at Lausanne University Hospital (CHUV) until end of 2018. Through this continued commitment
IUMSP has been our main funder during the reporting period as before. In 2017, a comprehensive
reorganisation of several academic institutions affiliated with CHUV has been launched by the
Canton of Vaud, which took more concrete forms during 2018. As a consequence, our host
institution was formally merged with the Department of Ambulatory Care and Community
Medicine (Policlinique Médical Universitaire) and several other institutions to become a large
academic health centre, the Center for Primary Care and Public Health (Unisanté) of the University
of Lausanne.

Besides the local involvement, our team members were active in a range of national and
international networks, advisory bodies, and professional associations. These activities contribute
to the promotion of Cochrane’s role in evidence-based healthcare. In 2017 and 2018, memberships
included:

        •   Coordination pour l’Evaluation des Pratiques Professionnelles en Santé en Rhône-Alpes
            (CEPPRAL);
        •   Federal Commission on Mandatory insurance, Federal Office of Public Health (CFPP-
            ELGK);
        •   Enhancing the QUAlity and Transparency Of health Research (EQUATOR Network);
        •   Scientific Advisory Committee on the Quality Strategy for the Swiss Health Care
            System, Federal Office of Public Health (FOPH);
        •   Fédération Romande des Consommateurs (FRC);
        •   German Network for Evidence-based Medicine (DNEbM);
        •   Grading of Recommendations Assessment, Development and Evaluation (GRADE)
            Working Group;
        •   International Methodology Consortium on Coded Health Information (IMECCHI);
        •   Public Health Switzerland;
        •   Réseau d’Epidémiologie Clinique International Francophone (RECIF-Euro-
            Mediterranean branch of INCLEN (International Network on Clinical Epidemiology);
        •   STrengthening the Reporting of OBservational studies in Epidemiology (STROBE)
            Initiative;
        •   Swiss Network for Health Technology Assessment (SNHTA);
        •   Topic Advisory Group ‘Quality and Safety’, WHO.
Biennial Report 2017 & 2018                                                                     16

1.4.3 Indicators

Website traffic for swiss.cochrane.org

Access statistics provided by Google Analytics indicated a stable number of sessions with our
website opened throughout 2017 and 2018. In early 2016, the number of sessions had peaked at
the time of the launch of the national provision of the Cochrane Library. In 2017 and 2018, the
access numbers remained well above the level of 2015 and earlier.

   Number of Sessions and Users per Year
  35000

  30000                                                                         Sessions
                                                                                Users
  25000

  20000

  15000

  10000

   5000

         0
                2014        2015           2016          2017            2018

   Number of Sessions per Month
  9000
                  Official announcement of the Cochrane Library Sw iss
                  national provision in 2016
  8000                                                                          2016
  7000                                                                          2017
  6000                                                                          2018
  5000

  4000
  3000
  2000

  1000
     0
             JAN FEB MAR APR MAY JUN JUL AUG SEP OCT NOV DEC

About 17000 users visited our website per year. A smaller proportion (13%) were first-time visitors
but most (87%) were return visitors. The average time spent on the website was just above two
minutes, and users opened an average of 2.7 pages during this time. Most sessions (58%) originated
in Switzerland or the neighbouring European countries, in particular France and Germany. In
Switzerland, the cantons of Zurich, Vaud and Berne had particularly high numbers of users.
Biennial Report 2017 & 2018                                                                   17

Newsletter

In 2017, we published two numbers of our newsletter and in 2018 another two, all were in the
three languages English, French and German. All issues are also available for download from our
website. Between December 2016 and December 2018 the number of subscriptions increased by
28% from 276 to 352.
Biennial Report 2017 & 2018                                                                         18

2. Our team
By the end of 2018, our team consisted of four full- or part-time staff members,
who were employees of our host institution IUMSP Lausanne. Several
additional IUMSP collaborators and external Cochrane members contributed
to activities of Cochrane Switzerland and are listed below. The past two years
saw a number of changes in our team:

    In May 2017, Annegret Borchard joined our team as scientific collaborator in charge of
    activities related to Cochrane Public Health Europe and knowledge translation in German
    language including our involvement in the collaborative projects Cochrane Kompakt and the
    blog “Wissen Was Wirkt”.

    In June 2018, Fabrizio Barazzoni handed over to Giorgio Treglia as the Cochrane
    representative in Ticino, the Italian speaking part of Switzerland. Giorgio is head of the
    hospital-based HTA unit and consultant physician in nuclear medicine at EOC Bellinzona, as
    well as an associate physician at the Lausanne University Hospitals. His particular interest is in
    promoting the production and use of diagnostic reviews.

    In August 2018, Bernard Burnand retired from his position as professor at the University of
    Lausanne and head of the Health Care Evaluation Unit at IUMSP. He had joined the institute in
    2003 and had co-founded Cochrane Switzerland in 2010 together with Erik von Elm. After eight
    years of joint leadership of Cochrane Switzerland, he handed over to Erik von Elm as the
    director of Cochrane Switzerland. Bernard continues his involvement in evidence-based health
    care and knowledge transfer on a voluntary basis. In his role as head of the IUMSP Health Care
    Evaluation Unit he was succeeded by Isabelle Peytremann Bridevaux.

    In August 2018, our scientific collaborator Thomy Tonia and our coordinator Claudia Burdet
    left the team. Thomy has contributed to the Scientific Secretariat of the Swiss Medical Board
    and one of our evidence synthesis mandates. Claudia was much involved in the project with
    the Féderation Romande de Consommateurs besides her function as coordinator.

    Muaamar Al-Gobari defended his PhD thesis on 19th July 2018 and graduated from the
    Faculty of Biology and Medicine of the University of Lausanne. We hope to be able to involve
    him as a post-doc researcher in our regular activities in the near future.
Biennial Report 2017 & 2018                                                               19

Core team members:
Annegret Borchard, MSc; scientific collaborator
Lucienne Boujon; secretary
Erik von Elm, MD, MSc, FMH; director Cochrane Switzerland
Claudia Burdet, PhD; coordinator (till August 2018)
Bernard Burnand, MD, MPH; professor, director Cochrane Switzerland (till July 2018)
Isabelle Peytremann Bridevaux, MD, MPH, DSc; professor (team member till December 2018)
Thomy Tonia, MSc; scientific collaborator (till August 2018)

Associated team members:
Muaamar Al-Gobari, PhD, MSc, MPH; scientific collaborator
Chantal Arditi, MSc, MA; scientific collaborator, PhD student
Pierluigi Ballabeni, MSc, PhD; statistician (in charge of web content in Italian)
Marie-Annick Le Pogam, MD MPH; scientific collaborator, PhD student
Stefania Massetti-Pelli, MBA; scientific collaborator in Ticino
Patrick Taffé, MSc, PhD, statistician
Giorgio Treglia, MD, MSc (HTA), Cochrane representative in Ticino, eoc Bellinzona
Kathelene Weiss, MA; Development Coordinator, Cochrane Central Executive
Biennial Report 2017 & 2018                                                               20

3. Key financial data
The figure below shows the total budget of Cochrane Switzerland for the years
2013 to 2018

Figure: Budget in CHF

     500'000

     450'000

     400'000

     350'000

     300'000
                                                               Course & other
     250'000                                                   income
     200'000
                                                               Grants & mandates
     150'000

     100'000
                                                               Contribution from host
      50'000                                                   Institution

           0
                2013      2014   2015   2016   2017   2018

Cochrane Switzerland received in-kind support from the Institute of Social and Preventive
Medicine (IUMSP) at the Lausanne University Hospital (CHUV). Some of the research conducted
by IUMSP is complementary to the work of Cochrane Switzerland, for example in the areas of
knowledge translation, public health or health services research. Resources related to these
projects are not included in the above financial overview.
Biennial Report 2017 & 2018                                                                             21

Annex 1 - Peer reviewed articles by our
team in 2017 and 2018
2017:
        Aerts, M, Minalu, G, Bösner, S, Buntinx, F, Burnand, B, Haasenritter, J, Herzig, L, J
        Knottnerus, A, Nilsson, S, Renier, W, Sox, C, Sox, H, Donner-Banzhoff, N. Pooled
        individual patient data from five countries were used to derive a clinical prediction rule for
        coronary artery disease in primary care Journal Of Clinical Epidemiology 81 (2017) 120-128.

        Alexandre K, Desrichard O, Burnand B, Peytremann-Bridevaux I. Factors influencing self-
        management in adults with diabetes: an umbrella review protocol. Jbi Database Of
        Systematic Reviews And Implementation Reports 15 (2017) 2630-2637.

        Al-Gobari M, Le HH, Fall M, Gueyffier F, Burnand B. No benefits of statins for sudden
        cardiac death prevention in patients with heart failure and reduced ejection fraction: A
        meta-analysis of randomized controlled trials. Plos One 12 (2017) e0171168.

        Alturki R, Schandelmaier S, Olu KKalu, von Niederhäusern, B, Agarwal, A, Frei,
        R, Bhatnagar, N, Hooft, L, von Elm, E, Briel, M. Premature trial discontinuation often not
        accurately reflected in registries: comparison of registry records with publications.
        Journal of Clinical Epidemiology 81 (2017) 56-63.

        Amstutz A, Schandelmaier, S, Frei, R, Surina, J, Agarwal, A, Olu, KKalu, Alturki, R, von
        Niederhäusern, B, von Elm, E, Briel, M. Discontinuation and non-publication of
        randomised clinical trials supported by the main public funding body in Switzerland: a
        retrospective cohort study. Bmj Open 7 (2017) e016216.

        Arditi C, Rège-Walther M, Durieux P, Burnand B. Computer-generated reminders
        delivered on paper to healthcare professionals: effects on professional practice and
        healthcare outcomes.The Cochrane Database Of Systematic Reviews 7 (2017) CD001175.

        Baggio S, Iglesias, K, Hugli, O, Burnand, B, Ruggeri, O, Wasserfallen, J-B, Moschetti,
        K, Staeger, P, Alary, S, Allen, MCanepa, Daeppen, J-B, Bodenmann, P. Associations
        between perceived discrimination and health status among frequent Emergency
        Department users. European Journal Of Emergency Medicine 24 (2017) 136-141.

        Bodenmann P, Velonaki V-S, Griffin JL, Baggio, S, Iglesias, K, Moschetti, K, Ruggeri,
        O, Burnand, B, Wasserfallen, J-B, Vu, F, Schupbach, J, Hugli, O, Daeppen, J-P. Case
        Management may Reduce Emergency Department Frequent use in a Universal Health
        Coverage System: a Randomized Controlled Trial. Journal Of General Internal Medicine 32
        (2017) 508-515.

        Briel M, Elger B, von Elm E, Satalkar P. Insufficient recruitment and premature
        discontinuation of clinical trials in Switzerland: qualitative study with trialists and other
        stakeholders. Swiss Medical Weekly 147 (2017) w14556.
Biennial Report 2017 & 2018                                                                        22

        Carron, T, Bridevaux, P-O, Lörvall, K, Parmentier, R, Moix, J-B, Beytrison, V, Pernet,
        R, Rey, C, Roberfroid, P-Y, Chhajed, PN, Dieterle, T, Zellweger, LJoos, Kohler, M, Maier,
        S, Miedinger, D, Thurnheer, R, Urwyler, P, Tschopp, J-M, Zuercher, E, Leuppi,
        JDaniel, Burnand, B, Peytremann-Bridevaux, I. Feasibility, acceptability and
        effectiveness of integrated care for COPD patients: a mixed methods evaluation of a pilot
        community-based programme. Swiss Medical Weekly 147 (2017) w14567.

        Deruaz-Luyet A, A N'Goran, A, Senn, N, Bodenmann, P, Pasquier, J, Widmer, D, Tandjung,
        R, Rosemann, T, Frey, P, Streit, S, Zeller, A, Haller, DM, Excoffier, S, Burnand, B, Herzig,
        L. Multimorbidity and patterns of chronic conditions in a primary care population in
        Switzerland: a cross-sectional study.. Bmj Open 7 (2017) e013664.

        Dubois J, Scala E, Faouzi M, Decosterd I, Burnand B, Rodondi P-Y. Chronic low back pain
        patients' use of, level of knowledge of and perceived benefits of complementary medicine:
        a cross-sectional study at an academic pain center. Bmc Complementary And Alternative
        Medicine 17 (2017) 193.

        Ducrest I, Marques-Vidal P, Faouzi M, Burnand B, Waeber G, Rodondi P-Y.
        Complementary medicine use among general internal medicine inpatients in a Swiss
        university hospital. International Journal Of Clinical Practice 71 (2017) 1-8.

        Forster AJ, Burnand B, Drösler SE, Gurevich, Y, Harrison, J, Januel, J-M, Romano,
        PS, Southern, DA, Sundararajan, V, Quan, H, Vanderloo, SE, Pincus, HA, Ghali, WA. A
        World Health Organization field trial assessing a proposed ICD-11 framework for
        classifying patient safety events. International Journal For Quality In Health Care 29 (2017)
        548-556.

        Gijs E, Zuercher E, Henry V, Morin D, Bize R, Peytremann-Bridevaux I. Diabetes care:
        Comparison of patients' and healthcare professionals' assessment using the PACIC
        instrument. Journal Of Evaluation In Clinical Practice 23 (2017) 803-811.

        Gilles I, Mayer M, Courvoisier N, Peytremann-Bridevaux I. Joint analyses of open
        comments and quantitative data: Added value in a job satisfaction survey of hospital
        professionals. Plos One 12 (2017) e0173950.

        Halfon P, Staines A, Burnand B. Adverse events related to hospital care: a retrospective
        medical records review in a Swiss hospital.International Journal For Quality In Health Care:
        Journal Of The International Society For Quality In Health Care 29 (2017) 527-533.

        Konstantinidis L, Carron, T, de Ancos, E, Chinet, L, Hagon-Traub, I, Zuercher,
        E, Peytremann-Bridevaux, I. Awareness and practices regarding eye diseases among
        patients with diabetes: a cross sectional analysis of the CoDiab-VD cohort. Bmc Endocrine
        Disorders 17 (2017) 56.

        Le Pogam, M-A, Quantin, C, Reich, O, Tuppin, P, Fagot-Campagna, A, Paccaud,
        F, Peytremann-Bridevaux, I, Burnand, B. Geriatric Patient Safety Indicators Based on
        Linked Administrative Health Data to Assess Anticoagulant-Related Thromboembolic and
        Hemorrhagic Adverse Events in Older Inpatients: A Study Proposal. Jmir Research
        Protocols 6 (2017) e82.
Biennial Report 2017 & 2018                                                                        23

        Pillai N, Dusheiko M, Burnand B, Pittet V. A systematic review of cost-effectiveness
        studies comparing conventional, biological and surgical interventions for inflammatory
        bowel disease. Plos One 12 (2017) e0185500.

        Pittet V, Vaucher C, Froehlich F, Burnand B, Michetti P, Maillard MH. Patient self-reported
        concerns in inflammatory bowel diseases: A gender-specific subjective quality-of-life
        indicator. Plos One 12 (2017) e0171864.

        Rosselet P, Hagon-Traub I, Burnand B, Konstantidinis L, Ambresin A. Prévention et prise
        en charge de la rétinopathie diabétique - Prise en charge multidisciplinaire du diabète :
        recommandations pour la pratique clinique []
        Revue Medicale Suisse 13 (2017) 1217

        Rosselet P, Hagon-Traub I, Burnand B. Autosurveillance de la glycémie lors du diabète :
        Prise en charge multidisciplinaire du diabète : recommandations pour la pratique clinique.
        Revue Medicale Suisse 13 (2017) 665.

        Rosselet P, Hagon-Traub I, Burnand B. Education thérapeutique du patient à l’autogestion
        du diabète: Prise en charge multidisciplinaire du diabète : recommandations pour la
        pratique clinique. Revue Médicale Suisse 13 (2017) 768.

        Rosselet P, Hagon-Traub I, Burnand B. Questions spécifiques au diabète chez les
        personnes âgées : prise en charge multidisciplinaire du diabète : recommandations pour la
        pratique clinique. Revue Medicale Suisse 13 (2017) 769.

        Rosselet P, Hagon-Traub I, Burnand B. Diagnostic et prise en charge du diabète
        gestationnel : prise en charge multidisciplinaire du diabète : recommandations pour la
        pratique clinique. Revue Médicale Suisse 13 (2017) 1305.

        Rosselet P, Zuercher E, Pasquier J, Burnand B, Peytremann-Bridevaux I. Impact of
        forgoing care because of costs on the quality of diabetes care: A three-year cohort study.
        European Journal Of Internal Medicine 41 (2017) e35-e37.

        Santschi, V, Wuerzner, G, Chiolero, A, Burnand, B, Schaller, P, Cloutier, L, Paradis,
        G, Burnier, M. Team-based care for improving hypertension management among
        outpatients (TBC-HTA): study protocol for a pragmatic randomized controlled trial. Bmc
        Cardiovascular Disorders 17 (2017) 39.

        Schandelmaier, S, Tomonaga, Y, Bassler, D, Meerpohl, JJ, von Elm, E, You, JJ, Bluemle,
        A, Lamontagne, F, Saccilotto, R, Amstutz, A, Bengough, T, Stegert, M, Olu, KK, Tikkinen,
        KAO, Neumann, I, Carrasco-Labra, A, Faulhaber, M, Mulla, SM, Mertz, D, Akl, EA, Sun,
        X, Busse, JW, Ferreira-Gonzalez, I, Nordmann, A, Gloy, V, Raatz, H, Moja, L, Rosenthal,
        R, Ebrahim, S, Vandvik, PO, Johnston, BC, Walter, MA, Burnand, B, Schwenkglenks,
        M, Hemkens, LG, Guyatt, G, Bucher, HC, Kasenda, B, Briel, M. Premature Discontinuation
        of Pediatric Randomized Controlled Trials: A Retrospective Cohort Study. The Journal Of
        Pediatrics 184 (2017) 209-214.e1

        Schmucker CM, Blümle, A, Schell, LK, Schwarzer, G, Oeller, P, Cabrera, L, von Elm,
        E, Briel, M, Meerpohl, JJ. Systematic review finds that study data not published in full text
        articles have unclear impact on meta-analyses results in medical research. Plos One 12
        (2017) e0176210.
Biennial Report 2017 & 2018                                                                         24

        Schweizer A, Morin D, Henry V, Bize R, Peytremann-Bridevaux I. Interprofessional
        collaboration and diabetes care in Switzerland: A mixed-methods study. Journal Of
        Interprofessional Care 31 (2017) 351-359.

        Southern, DA, Burnand, B, Droesler, SE, Flemons, W, Forster, AJ, Gurevich, Y, Harrison,
        J, Quan, H, Pincus, HA, Romano, PS, Sundararajan, V, Kostanjsek, N, Ghali, WA. Deriving
        ICD-10 Codes for Patient Safety Indicators for Large-scale Surveillance Using
        Administrative Hospital Data. Medical Care 55 (2017) 252-260.

        Toews I, Binder N, Wolff RF, Toprak G, von Elm E, Meerpohl JJ. Guidance in author
        instructions of hematology and oncology journals: A cross sectional and longitudinal
        study. Plos One 12 (2017) e0176489.

        von Elm E. Switzerland voted against a universal basic income. Bmj (Clinical Research
        Ed.) 356 (2017) j191.

        Zuercher E, Diatta IDina, Burnand B, Peytremann-Bridevaux I. Health literacy and
        quality of care of patients with diabetes: A cross-sectional analysis.
        Primary Care Diabetes 11 (2017) 233-240.

2018:
        Al-Gobari M, Al-Aqeel S, Gueyffier F, Burnand B. Effectiveness of drug interventions to
        prevent sudden cardiac death in patients with heart failure and reduced ejection fraction:
        an overview of systematic reviews. Bmj Open 8 (2018) e021108.

        Amstutz A, Schandelmaier S, Frei R, Surina J, Agarwal A, Alturki R, von Niederhäusern B,
        von Elm E, Briel M. Funding characteristics of randomised clinical trials supported by the
        Swiss National Science Foundation: a retrospective cohort study. Swiss Medical Weekly
        148 (2018) w14587.

        Arditi C, Iglesias K, Peytremann-Bridevaux I. The use of the Patient Assessment of
        Chronic Illness Care (PACIC) instrument in diabetes care: a systematic review and meta-
        analysis. International Journal For Quality In Health Care (2018).

        Arditi C, Zanchi A, Peytremann-Bridevaux I. Health status and quality of life in patients
        with diabetes in Switzerland. Primary Care Diabetes (2018).

        Bashkin O, Horne R, Peytremann-Bridevaux I. Influence of Health Status on the
        Association Between Diabetes and Depression Among Adults in Europe: Findings From
        the SHARE International Survey. Diabetes Spectrum 31 (2018) 75-82.

        Deruaz-Luyet, A, N'Goran, AA, Pasquier, J, Burnand, B, Bodenmann, P, Zechmann, S,
        Neuner-Jehle, S, Senn, N, Widmer, D, Streit, S, Zeller, A, Haller, DM, Herzig, L.
        Multimorbidity: can general practitioners identify the health conditions most important to
        their patients? Results from a national cross-sectional study in Switzerland.. Bmc Family
        Practice 19 (2018) 66.

        Filliettaz SSchusselé, Berchtold P, Kohler D, Peytremann-Bridevaux I. Integrated care in
        Switzerland: Results from the first nationwide survey. Health Policy 122 (2018) 568-576.
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