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Blood
Purification
Blood Purification - Karger Publishers
The first-in-class Open Access
journal focusing exclusively on
the glomerulus

                                                                 NEW
                                                               JOURNAL
                                                                 2021

                      Glomerular
                      Diseases
                      The rst-in-class Open Access journal
                      focusing exclusively on the glomerulus

                                                                         KI20265

                 karger.com/gdz
Blood Purification - Karger Publishers
Blood
                      Purification
                      Founded 1983 by K. Schaefer;
                      continued by L.W. Henderson (1989–2000), K.M.L. Leunissen (2001–2007)

Official Journal of   Editor-in-Chief
                      Claudio Ronco – St. Bartolo Hospital, Vicenza, Italy

                      Clinical Engineering
                      William R. Clark – Purdue University, West Lafayette, IN, USA
                      Hideyuki Kawanashi – Tsuchiya General Hospital, Hiroshima, Japan
                      Tadayuki Kawasaki – Mobara Clinic, Mobara City, Japan
                      Jeongchul Kim – Wake Forest School of Medicine, Winston-Salem, NC, USA
                      Anna Lorenzin – International Renal Research Institute of Vicenza, Vicenza, Italy
                      Ikuto Masakane – Honcho Yabuki Clinic, Yamagata City, Japan
                      Michio Mineshima – Tokyo Women’s Medical University, Tokyo, Japan
                      Tomotaka Naramura – Kurashiki University of Science and the Arts, Kurashiki, Japan
                      Mauro Neri – International Renal Research Institute of Vicenza, Vicenza, Italy
                      Masanori Shibata – Koujukai Rehabilitation Hospital, Nagoya City, Japan
                      Yoshihiro Tange – Kyushu University of Health and Welfare, Nobeoka-City, Japan
                      Yoshiaki Takemoto – Osaka City University, Osaka City, Japan

Affiliated with       Critical Care Nephrology
                      Stefan D. Anker – Charité Universitätsmedizin Berlin, Berlin, Germany
                      Massimo Antonelli – Università Cattolica del Sacro Cuore, Rome, Italy
                      Nadia Aspromonte – Fondazione Policlinico Universitario, Rome, Italy
                      Sean M. Bagshaw – University of Alberta, Edmonton, AB, Canada
                      Ian C. Baldwin – Austin Hospital, Heidelberg, VIC, Australia
                      Rinaldo Bellomo – Austin Hospital, Heidelberg, VIC, Australia
                      Guido Bertolini – Istituto di Ricerche Farmacologiche Mario Negri, Ranica, Italy
                      W. Kline Bolton – University of Virginia Health System, Charlottesville, VA, USA
                      Joseph V. Bonventre – Brigham and Women’s Hospital, Boston, MA, USA
                      Jorge Cerda – Albany Medical College, Albany, NY, USA
                      Lakhmir Chawla – George Washington University, Washington DC, USA
                      Maria Rosa Costanzo – Edward Heart Hospital, Naperville, IL, USA
                      Andrew Davenport – University College London, London, UK
                      Luca Di Lullo – Delfino Hospital, Colleferro, Italy
                      Salvatore Di Somma – University La Sapienza Rome, Rome, Italy
                      Fiorenza Ferrari – International Renal Research Institute of Vicenza, Vicenza, Italy
                      Enrico Fiaccadori – Università degli Studi di Parma, Parma, Italy
                      Michael Haase – Otto-von-Guericke University, Magdeburg, Germany
                      William L. Henrich – UT Health Science Center, San Antonio, TX, USA

                                                                                                         (Continued on next page)

                                                                             Printed in Germany on acid-free and non-aging paper
                                                                             (ISO 9706) by Stückle Druck, Ettenheim
(Continued)

Patrick Honoré – CHU Brugmann University Hospital, Brussels, Belgium
Eric A. Hoste – University of Ghent, Ghent, Belgium
Nevin M. Katz – Johns Hopkins University, Baltimore, MD, USA
John A. Kellum – University of Pittsburgh, Pittsburgh, PA, USA
Alan Maisel – VA San Diego Healthcare System, San Diego, CA, USA
Alexandre Mebazaa – University Paris 7, Paris, France
Ravindra Mehta – University of California, San Diego, CA, USA
Bruce A. Molitoris – Indiana University School of Medicine, Indianapolis, IN, USA
Patrick T. Murray – University College Dublin, Dublin, Ireland
Mark Okusa – University of Virginia, Charlottesville, VA, USA
Marlies Ostermann – King’s College London, London, UK
Heleen M. Oudemans-van Straaten – Vrije Universiteit Medical Center, Amsterdam,
    The Netherlands
Paul M. Palevsky – University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Didier Payen – Université Paris 7, Paris, France
Zhiyong Peng – University of Wuhan, Wuhan, China
Piotr Ponikowski – Medical University, Wroclaw, Poland
John R. Prowle – Royal London Hospital, London, UK
V. Marco Ranieri – Università di Torino, Turin, Italy
Marie Schetz – University Hospital Leuven, Leuven, Belgium
Antoine Schneider – Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
Andrew Shaw – University of Alberta, Edmonton, AB, Canada
Shigehiko Uchino – Jikei University School of Medicine, Minatoku, Japan
Gianluca Villa – University of Florence, Florence, Italy
Salvatore Giovanni Vitale – University of Catania, Catania, Italy
David Warnock – University of Alabama at Birmingham, Birmingham, AL, USA
Alexander Zarbock – University of Münster, Münster, Germany

Pediatric Section
David J. Askenazi – University of Alabama at Birmingham, Birmingham, AL, USA
Akash Deep – King’s College Hospital, London, UK
Stuart L. Goldstein – University of Cincinnati, Cincinnati, OH, USA
Il-Soo Ha – Seoul National University, Seoul, Republic of Korea
Zaccaria Ricci – Bambino Gesù Children’s Hospital, Rome, Italy
Rukshana Shroff – Great Ormond Street Hospital for Children, London, UK
Scott M. Sutherland – Stanford School of Medicine, Palo Alto, CA, USA
Michael Zappitelli – Peter Gilgan Centre for Research and Learning, Toronto, ON, Canada

Peritoneal Dialysis
Richard Amerling – St. George’s University School of Medicine, St. George’s, Grenada
Clémence Béchade – CHU Caen Normandie, Caen, France
Jordi Bover – Fundació Puigvert, Barcelona, Spain
John Burkart – Wake Forest University Medical Center, Winston-Salem, NC, USA
Irene Capelli, S. Orsola – Malpighi University Hospital, Bologna, Italy
Anne-Lorraine Clause – Cliniques Universitaires de Bruxelles, Brussels, Belgium
Ricardo Correa-Rotter – National Medical Science and Nutrition Institute, Mexico City, Mexico
Carlo Crepaldi – San Bortolo Hospital, Vicenza, Italy
Fredric Finkelstein – Yale University, New Haven, CT, USA
Anna Giuliani – Ospedale San Bortolo, Vicenza, Italy

                                                                                (Continued on next page)

                                                   © 2021 S. Karger AG, Basel
                                                   www.karger.com
                                                   karger@karger.com
(Continued)

David Goldsmith – Foundation Hospital, London, UK
Olof Heimburger – Karolinska University Hospital, Stockholm, Sweden
Diego Ingrosso – University of Campania, Naples, Italy
Raymond T. Krediet – Academic Medical Center, Amsterdam, The Netherlands
Vincenzo La Milia – A. Manzoni Hospital, Lecco, Italy
Zhi-Hong Liu – Nanjing University School of Medicine, Nanjing, China
Rajnish Mehrotra – University of Washington, Seattle, WA, USA
Piergiorgio Messa – Fondazione IRCCS Ca’ Granda OMP, Milan, Italy
Andrew Mooney – Leeds Teaching Hospitals, Leeds, UK
K. Shivanand Nayak – Global Hospitals, Hyderabad, India
Miguel Perez Fontan – University of A Coruña, A Coruña, Spain
Beth Marie Piraino – University of Pittsburgh, Pittsburgh, PA, USA
Miguel C. Riella – Catholic University of Parana, Curitiba, Brazil
Jean-Philippe Rycelynck – CHU Clémenceau, Caen, France
Dirk G. Struijk – Academic Medical Center, Amsterdam, The Netherlands
Isaac Teitelbaum – University of Colorado, Aurora, CO, USA
Josep Teixido-Planas – Hospital Universitari Germans Trias i Pujol, Badalona, Spain
Wim Van Biesen – University Hospital Ghent, Ghent, Belgium
Janusz Witowski – Poznan University, Poznan, Poland

Hemodialysis
Pedro Aljama – Hospital Universitario Reina Sofia, Cordoba, Spain
Rasheed A. Balogun – University of Virgina, Charlotteville, VA, USA
Antonio Bellasi – ASST Papa Giovanni XXIII, Bergamo, Italy
Stefano Bianchi – Ospedale San Donato, Arezzo, Italy
James O. Burton – Leicester General Hospital, Leicester, UK
P.K.G. Chandran – University of Iowa, Des Moines, IA, USA
Nan B. Chen – Shanghai Jiao Tong University, Shanghai, China
John Collins – Auckland District Health Board, Auckland, New Zealand
Adrian A. Covic – University Gr T Popa Iasi, Iasi, Romania
Renato Eick – Hospital Moinhos de Vento, Porto Alegre, Brazil
Mario Cozzolino – University of Milan, Milan, Italy
Dick de Zeeuw – University Medical Center Groningen, Groningen, The Netherlands
Francesco Galli – University of Perugia, Perugia, Italy
Victor Gura – Cedars Sinai Medical Center, Beverly Hills, CA, USA
Colin A. Hutchison – Hastings Hospital, Hastings, New Zealand
Talat Alp Ikizler – Vanderbilt University Medical Center, Nashville, TN, USA
Hideyuki Kawanishi – Tsuchiya General Hospital, Hiroshima, Japan
William F. Keane – University of Minnesota, Minneapolis, MN, USA
Peter Kotanko – Renal Research Institute, New York, NY, USA
Martin K. Kuhlmann – Vivantes Klinikum im Friedrichshain, Berlin, Germany
Gaetano La Manna – University of Bologna, Bologna, Italy
Nathan W. Levin – Renal Research Institute, New York, NY, USA
Francesco Locatelli – Azienda Ospedaliera della Provincia di Lecco, Lecco, Italy
Peter A. McCullough – Baylor University Medical Center, Dallas, TX, USA
Madhukar Misra – University of Missouri Columbia, Columbia, MO, USA
Zhaohui Ni – Shanghai Jiao Tong University, Shanghai, China
Allen R. Nissenson – UCLA – Medical Center, Los Angeles, CA, USA
Mark Okusa – University of Virginia, Charlottesville, VA, USA

                                                                                 (Continued on next page)

                                                    © 2021 S. Karger AG, Basel
                                                    www.karger.com
                                                    karger@karger.com
(Continued)

Vincenzo Panichi – Versilia Hospital, Lido di Camaiore, Italy
Mauro Pittiruti – Catholic University, Rome, Italy
Michael Rocco – Wake Forest University, Winston-Salem, NC, USA
Mitchell H. Rosner – University of Virginia Health System, Charlottesville, VA, USA
Daniel Schneditz – Medical University of Graz, Graz, Austria
Peter Stenvinkel – Karolinska University Hospital, Stockholm, Sweden
Enric Vilar – Lister Hospital, Stevenage, UK
Stephan von Haehling – Georg-August-Universität, Göttingen, Germany
Angela Y. Wang – University of Hong Kong, Hong Kong
Weiming Wang – Shanghai Jiao Tong University, Shanghai, China
Jingyuan Xie – Shanghai Jiao Tong University, Shanghai, China
Robert Zietse – Erasmus MC, Rotterdam, The Netherlands
Carmine Zoccali – Ospedali Riuniti, Reggio Calabria, Italy
Li Zuo – Peking University People’s Hospital, Beijing, China

                                                     © 2021 S. Karger AG, Basel
                                                     www.karger.com
                                                     karger@karger.com
Journal Information

                                                            Aims and Scope
                                                            Practical information on hemodialysis, hemofiltration, peritoneal dialysis and apheresis is
                                                            featured in this journal. Recognizing the critical importance of equipment and procedures,
                                                            particular emphasis has been placed on reports, drawn from a wide range of fields, describ-
                                                            ing technical advances and improvements in methodology. Papers reflect the search for
                                                            cost-effective solutions which increase not only patient survival but also patient comfort and
Guidelines for Authors                                      disease improvement through prevention or correction of undesirable effects. Advances in
We strongly encourage authors to read
the Guidelines for Authors at
                                                            vascular access and blood anticoagulation, problems associated with exposure of blood to
www.karger.com/bpu_guidelines prior to                      foreign surfaces and acute-care nephrology, including continuous therapies, also receive
submitting an article.                                      attention. Nephrologists, internists, intensivists and hospital staff involved in dialysis, apher-
                                                            esis and immunoadsorption for acute and chronic solid organ failure will find this journal
                                                            useful and informative. Blood Purification also serves as a platform for multidisciplinary expe-
                                                            riences involving nephrologists, cardiologists and critical care physicians in order to expand
                                                            the level of interaction between different disciplines and specialities.

Journal Contact
For questions or comments, please contact
the persons responsible who can be found at
http://www.karger.com/Journal/Contact/223997.

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                                                                                                              © 2021 S. Karger AG, Basel
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Vol. 50, No. 1, 2021

Contents

     World Kidney Day 2020: Editorial
  1 Kidney Health for Everyone Everywhere – From Prevention to Detection and
    Equitable Access to Care
     Li, P.K.-T. (Hong Kong); Garcia-Garcia, G. (Guadalajara); Lui, S.-F. (Hong Kong); Andreoli, S.
     (Indianapolis, IN); Fung, W.W.-S. (Hong Kong); Hradsky, A. (Brussels); Kumaraswami, L. (Chennai);
     Liakopoulos, V. (Thessaloniki); Rakhimova, Z. (Brussels); Saadi, G. (Giza); Strani, L. (Brussels); Ulasi, I.
     (Ituku-Ozalla); Kalantar-Zadeh, K. (Orange, CA); for the World Kidney Day Steering Committee

     Reviews
  9 Extracorporeal CO2 Removal Integrated within a Continuous Renal Replacement
    Circuit Offers Multiple Advantages
     Redant, S.; De Bels, D.; Barbance, O.; Loulidi, G.; Honoré, P.M. (Brussels)
 17 Extracorporeal Blood Purification and Organ Support in the Critically Ill Patient
     during COVID-19 Pandemic: Expert Review and Recommendation
     Ronco, C. (Padova/Vicenza); Bagshaw, S.M. (Edmonton, AB); Bellomo, R. (Melbourne, VIC); Clark, W.R.
     (West Lafayette, IN); Husain-Syed, F. (Giessen); Kellum, J.A. (Pittsburgh, PA); Ricci, Z. (Rome);
     Rimmelé, T. (Lyon); Reis, T. (Brasilia/London); Ostermann, M. (London)
 28 Heparin 2.0: A New Approach to the Infection Crisis
    Seffer, M.-T. (Braunschweig); Cottam, D.; Forni, L.G. (Guildford); Kielstein, J.T. (Braunschweig)

     Meta-Analysis
 35 Acute Kidney Injury in Coronavirus Disease 2019 Infected Patients:
     A Meta-Analytic Study
     Brienza, N.; Puntillo, F. (Bari); Romagnoli, S. (Florence); Tritapepe, L. (Rome)

     Hemodialysis – Meta-Analysis
 42 Technique Failure in Peritoneal Dialysis: Etiologies and Risk Assessment
    Da Luz, L.G. (Vicenza/São Paulo/Porto Alegre); Ankawi, G. (Vicenza/Jeddah); Digvijay, K. (Vicenza/
    Turin); Rosner, M.H. (Charlottesville, VA); Ronco, C. (Vicenza)

     Research Articles
 50 Efficacy and Safety of Regional Anticoagulation with 4% Trisodium Citrate Versus
     Heparin in Extended Hemodialysis among Critical Patients with Cancer and Acute
     Kidney Injury
     Moura, E.I.D.M.; de Brito, G.A.; Alves, J.A.; Imanishe, M.H.; Baptista, A.L.; Andrade, L.A.S.; Pereira, B.J.
     (Sao Paulo)

Cover illustration
© Departments of Radiology and Nephrology – S. Bortolo Hospital, Vicenza, Italy
And the International Renal Research Institute of Vicenza (IRRIV).
Flow dynamic study of a hemodialyzer with a helical scanning technique

                                                           © 2021 S. Karger AG, Basel

                                                           Access to full text and tables of contents,
                                                           including tentative ones for forthcoming issues:
                                                           www.karger.com/bpu
57 Infection Control Precautions and Care Delivery in Hemodialysis Unit during
      Coronavirus Disease 2019 Outbreak: A Case Series
      Hu, S.-C.; Fu, E.-Q.; Fan, J.-F.; Ye, Q.-Q.; Xia, C.; Gan, T.-E.; Ma, H.-Z. (Hangzhou)
 65 A Combination of Hemodialysis with Hemoperfusion Helped to Reduce the
      Cardiovascular-Related Mortality Rate after a 3-Year Follow-Up: A Pilot Study in
      Vietnam
      Nguyen Huu, D. (Ha Noi); Dao Bui Quy, Q. (Ho Chi Minh); Nguyen Thi Thu, H.; Phan The, C. (Ha Noi);
      Nguyen Thi Hong, Q. (Ninh Binh Province); Nguyen Duc, L. (Ho Chi Minh); Do, Q.; Le Viet, T. (Ha Noi)
 73 The Effects of Nebivolol and Irbesartan on Ambulatory Aortic Blood Pressure and
      Arterial Stiffness in Hemodialysis Patients with Intradialytic Hypertension
      Theodorakopoulou, M.; Loutradis, C.; Bikos, A.; Angeloudi, E.; Schoina, M. (Thessaloniki); Raptis, V.
      (Katerini); Liakopoulos, V.; Papagianni, A.; Sarafidis, P. (Thessaloniki)
 84 Relationship between Soluble ST2 and Left Ventricular Geometry in Maintenance
      Hemodialysis Patients
      Zhang, Z.; Xie, Y.; Shen, B.; Nie, Y.; Cao, X.; Xiang, F.; Zou, J. (Shanghai)
 93 Meeting Treatment Goals in Patients on Extramural Dialysis in Health Social Security
      in Mexico
      Muñoz-Menjivar, C.; Reyes-Sánchez, I.; Aguilar-Martínez, C.; Rodríguez-Rodríguez, A.;
      Mendoza-Gómez, J.L.; Guerrero-Soto, J.; Lizardi-Gómez, L.F.; Venegas-Vera, A.V.;
      Hernández-Rivera, J.C.H.; Ramos-Sánchez, A.; Paniagua, R. (Mexico City)
102 Prevalence, Characteristics, Risk Factors, and Outcomes of Invasively Ventilated
      COVID-19 Patients with Acute Kidney Injury and Renal Replacement Therapy
      Fominskiy, E.V.; Scandroglio, A.M.; Monti, G.; Calabrò, M.G.; Landoni, G.; Dell’Acqua, A.; Beretta, L.;
      Moizo, E.; Ravizza, A.; Monaco, F.; Campochiaro, C.; Pieri, M.; Azzolini, M.L.; Borghi, G.; Crivellari, M.;
      Conte, C.; Mattioli, C.; Silvani, P.; Mucci, M.; Turi, S.; Tentori, S.; Baiardo Redaelli, M.; Sartorelli, M.;
      Angelillo, P.; Belletti, A.; Nardelli, P.; Nisi, F.G.; Valsecchi, G.; Barberio, C.; Ciceri, F. (Milan);
      Serpa Neto, A. (Melbourne, VIC/Sao Paulo); Dagna, L. (Milan); Bellomo, R. (Melbourne, VIC);
      Zangrillo, A. (Milan); for the COVID-BioB Study Group
110 Impact of Medium Cut-Off Dialyzers on Patient-Reported Outcomes: COREXH
      Registry
      Alarcon, J.C.; Bunch, A.; Ardila, F.; Zuñiga, E.; Vesga, J.I. (Bogotá); Rivera, A. (Deerfield, IL); Sánchez, R.;
      Sanabria, R.M. (Bogotá)
119 Similarities, Differences, and Potential Synergies in the Mechanism of Action of
      Albumin Dialysis Using the MARS Albumin Dialysis Device and the CytoSorb
      Hemoperfusion Device in the Treatment of Liver Failure
      Dominik, A.; Stange, J. (Rostock)

      Case Reports
129 Continuous Renal Replacement Therapy for a Patient with Severe COVID-19
    Katagiri, D.; Ishikane, M.; Ogawa, T.; Kinoshita, N.; Katano, H.; Suzuki, T.; Fukaya, T.; Hinoshita, F.;
    Ohmagari, N. (Tokyo)
132 Identification of Complex Pneumonia during the Outbreak of COVID-19:
      Bacterial Pneumonia Combined with Acute Eosinophilic Pneumonia in Patients with
      Maintenance Hemodialysis
      Hu, Q. (Luzhou); Mao, N. (Chengdu); Huang, X.; Chen, D.; Zhang, Q. (Luzhou)
137 Successful Treatment of Severe Digitoxin Intoxication with CytoSorb®
      Hemoadsorption
      Breuer, T.G.K.; Quast, D.R.; Wiciok, S.; Labedi, A.; Ellrichmann, G. (Bochum)

                                                              © 2021 S. Karger AG, Basel

                                                              Access to full text and tables of contents,
                                                              including tentative ones for forthcoming issues:
                                                              www.karger.com/bpu
The Cappuccino videos
                                                                                                                          For an overview of the Cappuccino videos please go to:
                                                                                                                          www.karger.com/BPU-cappuccino

        Cappuccino
        with Claudio Ronco
        Blood Purification Journal Club
                                                                                                                                                                     Professor Claudio Ronco

        Especially in Italy, but also all over the world, people like to meet                                             Editor Blood Purification and Contributions to Nephrology
        over a cappuccino to talk about things like sports or politics be-                                                Director of the International Renal Research Institute of
                                                                                                                          Vicenza (IRRIV)
        fore rushing off for work.                                                                                        Director of the Department of Nephrology Dialysis and
        I would like to invite you to take a cappuccino with me and en-                                                   Transplantation, San Bortolo Hospital, Vicenza (Italy)
        gage in a conversation on topical issues in nephrology. As part of
        the ‘Cappuccino with Claudio Ronco’ series, I will monthly select
        articles recently published in Blood Purification and complement
        them with an expert comment in the form of a short video post-
        ed on the YouTube channel of the International Renal Research
        Institute of Vicenza and on Karger.com.

        Join the Blood Purification Journal Club and enjoy a
        Cappuccino with Claudio Ronco!

                                                                                                                                                                                                                             KI15429

                                    Contributions to Nephrology
Read it online:                     “... an invaluable collection on the nephrologist’s personal bookshelf.”
www.karger.com/cnp
                                    Journal of the Royal Society of Medicine

Series Editor                           Contributions to Nephrology
                                        Editor: C. Ronco
                                        Vol. 198
                                                                                        Contributions to Nephrology
                                                                                        Editor: C. Ronco
                                                                                                                                       Contributions to Nephrology
                                                                                                                                       Editor: C. Ronco
                                                                                                                                                                                               Contributions to Nephrology
                                                                                                                                                                                               Editor: C. Ronco
                                                                                        Vol. 197                                       Vol. 196                                                Vol. 195

C. Ronco, Vicenza                       CKD-Associated                                 Remote Patient                                 Recent Advances in                                       Recent Advances in the
                                        Complications: Progress in                                                                    Dialysis Therapy in Japan                                Pathogenesis and Treatment
                                        the Last Half Century                          Management in PD                                                                                        of Kidney Diseases
                                                                                                                                       Editor
                                                                                       Editors
                                        Editors                                                                                        H. Nakamoto                                             Editor
                                                                                       C. Ronco                                                                                                K. Nitta
                                        T. Nakanishi                                   C. Crepaldi                                     Co-Editors
                                        T. Kuragano                                    M.H. Rosner                                     K. Nitta
                                                                                                                                       K. Tsuchiya
                                                                                                                                       H. Okada
                                                                                                                                       H. Hasegawa

Contributions to                    Vol. 198: CKD-Associated                       Vol. 197: Remote Patient                        Vol. 196: Recent Advances in                            Vol. 195: Recent Advances
Nephrology                          Complications: Progress in                     Management in Peritoneal                        Dialysis Therapy in Japan                               in the Pathogenesis
Founded: 1975                       the Last Half Century                          Dialysis                                        JSDT Conference 2017,                                   and Treatment of Kidney
Field of Interest: Nephrology       Editors: Nakanishi, T.                         Editors: Ronco, C. (Vicenza); Crepaldi,         Yokohama, June 2017:                                    Diseases
Listed in bibliographic services,   (Nishinomiya/Kobe); Kuragano, T.               C. (Vicenza); Rosner, M.H.                      Selected Proceedings                                    Editor: Nitta, K. (Tokyo)
including: PubMed/MEDLINE,          (Nishinomiya)                                  (Charlottesville, VA)                                                                                   X + 148 p., 22 fig., 12 in color,
                                                                                                                                   Editors: Nakamoto, H. (Saitama);
Web of Science, Google Scholar      VIII + 148 p., 22 fig., 11 in color, 9 tab.,   VIII + 176 p., 33 fig., 28 in color, 13 tab.,                                                           17 tab., 2018
                                                                                                                                   Nitta, K.; Tsuchiya, K. (Tokyo);
                                    2019                                           2019                                                                                                    CHF 148.00 / EUR 138.00 / USD 174.00
ISSN 0302–5144                                                                                                                     Okada, H.; Hasegawa, H. (Saitama)
                                    CHF 148.00 / EUR 138.00 / USD 174.00           CHF 128.00 / EUR 120.00 / USD 152.00                                                                    (hard cover or online*)
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                                    (online**)                                     (online**)                                                                                              ISBN 978–3–318–06349–3
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Blood Purification
Y Journal Publication

                                                                   Techniques in Sepsis
                                                                   and AKI
                                                                   Editor
                                                                   Claudio Ronco

 Blood Purification Techniques in                                  Contents
 Sepsis and AKI
 Editor: Ronco, C. (Vicenza)
 64 p., 10 fig., 1 in color, 13 tab., 2019                         • Extracorporeal Blood Purification Therapies for Sepsis:
 CHF 39.00 / EUR 36.00 / USD 46.00                                   Monard, C.; Rimmelé, T.; Ronco, C.
 Soft cover or online prices for                                   • oXirisNet Registry: A Prospective, National Registry on the oXiris
 personal customers
 Prices subject to change, VAT not included                          Membrane: Villa, G.; De Rosa, S.; Samoni, S.; Neri, M.; Cosimo, C.;
 EUR price for eurozone countries,                                   Romagnoli S.; Gavagni, M.; Ronco, C.; De Gaudio A.R.
 USD price for USA and Latin America only                          • Practice of Extracorporeal Therapies for Septic Acute Kidney
 ISBN 978–3–318–06530–5                                              Injury Patients in Intensive Care Units in Mainland China:
 e-ISBN 978–3–318–06529–9
                                                                     Zhou, Y.; Zhou, F.; Wang, X.; Chang, P.; Zhang, L.; Yao, Q.; Goldstein, J.;
 Supplement Issue                                                    Liu, X.; Wang, M.
 Blood Purification                                                • oXiris® Use in Septic Shock: Experience of Two French Centres:
 Vol. 47, Suppl. 3 (2019)                                            Schwindenhammer, V.; Girardot, T.; Chaulier, K.; Grégoire, A.;
 Included in subscription                                            Monard, C.; Huriaux, L.; Illinger, J.; Leray, V.; Uberti, T.; Crozon-Clauzel, J.;
 Listed in MEDLINE/PubMed, Web of Science, Google
                                                                     Rimmelé, T.
 Scholar, Scopus, Embase                                           • Sepsis Management with a Blood Purification Membrane:
                                                                     European Experience: Pickkers, P.; Vassiliou, T.; Liguts, V.; Prato, F.;
                                                                     Tissieres, P.; Kloesel, S.; Turani, F.; Popevski, D.; Broman, M.;
                                                                     Gindac, C.M.; Saliba, F.; Tengattini, M.; Goldstein, J.; Harenski, K.
                                                                   • Hemofilter with Adsorptive Capacities: Case Report Series:
                                                                     Zhang, L.; Yan Tang G.K.; Liu, S.; Cai, J.; Chan, W.M.; Yang, Y.; Chang, P.;
                                                                     Wei, T.; Liu, X.; Yao, Q.; Wang, M.; Marshall, M.R.
                                                                   • Analysis of Endotoxin Adsorption in Two Swedish Patients with
                                                                     Septic Shock: Broman, M.E.; Bodelsson M.
                                                                   • Continuous Renal Replacement Therapy with the Adsorbing
                                                                     Filter oXiris in Septic Patients: A Case Series: Turani, F.;
                                                                     Barchetta, R.; Falco, M.; Busatti, S.; Weltert, L.
                                                                   • Augmented Adsorptive Blood Purification during Continuous
                                                                     Veno-Venous Haemodiafiltration in a Severe Septic, Acute
                                                                     Kidney Injury Patient: Use of oXiris®: A Single Centre Case Re-
                                                                     port: Tan, H.K.; Kaushik, M.; Tan, C.W.; Liew, Z.H.; Teo, S.H.; Loo, C.M.;
 Dear Librarian                                                      Ng, L.C.; Choong, L.H.L.; Foo, M.W.Y.
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End-Stage Kidney Disease:
Y Journal Publication

                                                                    A Multifaceted Discussion
                                                                    Editors
                                                                    Takeshi Nakanishi
                                                                    Takahiro Kuragano

  End-Stage Kidney Disease: A Multifaceted           Contents                                                          • Analysis of Extracellular Fluid Volume in Peritoneal
  Discussion
  Editors: Nakanishi, T. (Nishinomiya/Kobe);
                                                                                                                         Dialysis Patients before and after Kidney
  Kuragano, T. (Nishinomiya)                         Research Articles                                                   Transplantation: Kawamura, T.; Hyoudou, Y.; Nihei, H.;
  108 p., 32 fig., 8 in color, 32 tab., 2019         • Effect of Progression in Malnutrition and Inflam-                Kawamura, T.
  CHF 39.00 / EUR 36.00 / USD 46.00                                                                                    • Differential Impacts of Intravenous Iron Adminis-
  Soft cover or online prices for
                                                       matory Conditions on Adverse Events and Mortal-
  personal customers                                   ity in Patients on Maintenance Hemodialysis:                      tration and Iron-Containing Phosphate Binders on
  Prices subject to change, VAT not included          Toyoda, K.; Kuragano, T.; Kawada, H.; Taniguchi, T.;               Serum Intact Fibroblast Growth Factor 23 Levels:
  EUR price for eurozone countries,                   Nakanishi, T.                                                     Honda, H.; Tanaka, K.; Michihata, T.; Shibagaki, K.;
  USD price for USA and Latin America only           • Inhibition of the Mammalian Target of Rapamycin                  Yuza, T.; Hirao, K.; Tomosugi, N.; Shibata, T.
  ISBN 978–3–318–06486–5
  e-ISBN 978–3–318–06487–2                             May Augment the Increase in Soluble Klotho Lev-                 • Significance of Content of the Reticulocyte
                                                       els in Renal Transplantation Recipients: Mizusaki, K.;            Hemoglobin in the Management of Renal Anemia:
  Supplement Issue                                    Hasuike, Y.; Kimura, T.; Nagasawa, Y.; Kuragano, T.;              Ogawa, C.; Tsuchiya, K.; Nitta, K.; Maeda, K.
  Blood Purification                                  Yamada, Y.; Nojima, M.; Yamamoto, S.; Nakanishi, T.;             • Complications During Continuous Renal Replace-
  Vol. 47, Suppl. 2 (2019)
                                                      Ishihara, M.                                                       ment Therapy in Critically Ill Neonates: Nishimi, S.;
  Included in subscription
                                                     • Predilution On-Line Hemodiafiltration Improves                   Sugawara, H.; Onodera, C.; Toya, Y.; Furukawa, H.;
  Listed in MEDLINE/PubMed, Web of Science, Google
  Scholar, Scopus, Embase
                                                       Albumin Redox in Maintenance Hemodialysis                        Konishi, Y.; Sotodate, G.; Matsumoto, A.; Ishikawa, K.;
                                                       Patients: Shigematsu, T.; Kuragano, T.; Kamimura, T.;            Oyama, K.
                                                      Kawada, S.; Imamura, R.; Nishian, Y.; Miyamoto, M.;              • Aortic Arch Calcification and Bone-Associated
                                                      Miyamoto, T.; Nakanishi, T.                                        Molecules in Peritoneal Dialysis Patients:
                                                     • Association between the Cardio-Ankle Vascular                    Tsukada, M.; Miwa, N.; Hanafusa, N.; Tanaka, N.;
                                                       Index and Diabetes Mellitus-Related Peripheral                   Tsuchiya, K.; Nitta, K.
                                                       Arterial Disease in Chronic Hemodialysis Patients:              • Serum Magnesium Levels and Mortality in
                                                      Furuya, F.; Motosugi, A.; Haraguchi, K.; Hanai, S.; Ishii, T.;     Japanese Maintenance Hemodialysis Patients:
                                                      Yamaguchi, Y.; Kitamura, K.                                       Tamura, T.; Unagami, K.; Okazaki, M.; Komatsu, M.;
                                                     • Resistance to Erythropoiesis-Stimulating Agents in               Nitta, K.
                                                       Pre-Dialysis and Post-Dialysis Mortality in Japanese            • Strategies for the Super-Aged Dialysis Population:
                                                       Incident Hemodialysis Patients: Hayashi, T.; Joki, N.;            Survival Benefits or Alternative Goals?:
                                                      Tanaka, Y.; Iwasaki, M.; Kubo, S.; Matsukane, A.;                 Sakurai, S.; Hanafusa, N.; Nomura, T.; Tsuchiya, K.;
                                                      Takahashi, Y.; Imamura, Y.; Hirahata, K.; Hase, H.                Nitta, K.; Nangaku, M.
                                                     • Prevalence of Carnitine Deficiency and Decreased
                                                       Carnitine Levels in Patients on Hemodialysis:
 Dear Librarian                                       Hatanaka, Y.; Higuchi, T.; Akiya, Y.; Horikami, T.; Tei, R.;
 I have reviewed this publication and                 Furukawa, T.; Takashima, H.; Tomita, H.; Abe, M.
 would like to recommend it for our library.         • Prevalence and Severity of Itching in Patients with
 Recommended by:                                       End-Stage Renal Disease: Treatment with Nalfu-
                                                       rafine Hydrochloride: Nakamoto, H.; Kobayashi, T.;
                                                      Noguchi, T.; Kusano, T.; Ashitani, K.; Imaeda, H.;
                                                      Maezono, M.
 Department:                                         • Pre- and Postdialysis Uric Acid Difference and Risk
                                                       of Long-Term All-Cause and Cardiovascular Mor-
                                                       talities in Japanese Hemodialysis Patients; Miyazaki
                                                       Dialysis Cohort Study: Toida, T.; Sato, Y.; Komatsu, H.;
 Date:                                                Kitamura, K.; Fujimoto, S.

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CRRT Karger_B&W_CRRT Ad Karger 11/9/20 4:52 PM Page 1

         The 26th AKI & CRRT Conference continues to be the premier               Our 2021 virtual program will present exciting new develop-
         international meeting in the rapidly developing field of Critical        ments and evidence for patient assessments, diagnostic strategies,
         Care Nephrology and CRRT. It highlights the recent advances in           monitoring and management of AKI across different settings.
         our understanding of pathophysiology of critical illness, acute kidney   Best practices for applying biomarkers, fluid management,
         injury, emerging strategies in the management of sepsis, multiorgan      dialysis timing, and extracorporeal support for critically ill
         failure, development and use of biomarkers, technical advances in        patients will be addressed.
         CRRT and the appropriate utilization of these techniques.                As always, we hope to provide the right environment to foster
         Given the current state of the COVID-19 pandemic our meeting             learning and mutually beneficial communications and collaborations.
         will be presented in a virtual format in 2021. The program is            Please join us to share your knowledge and experience, as it is
         now designed to be offered over 6 days with the pre-conference           through multidisciplinary interactions and our collective efforts
         sessions (AKI Symposium and CCRT Workshop) on Sunday,                    that we will gain a better understanding of critical illness and
         Feb. 28 and Monday, March 1 and the main conference on                   learn how we can improve the lives of our patients.
         Tuesday, Mar. 2 through Friday, Mar. 5. We have developed an             We look forward to your participation in our Virtual Event!
         exciting, interactive platform to host the recorded sessions and
         stream live panel discussions following each plenary session.                                            Ravindra L. Mehta, MD
                                                                                                                                   Conference Chair
                                                         2021 Conference Topic Highlights:
          • Organ Dysfunction in the Critically Ill Patient • Acute Kidney Injury (AKI) • Controversies in Management of the Critically Ill Patient
                      • Special Sessions for Nurses and Allied Personnel • Challenges and Controversies in Renal Support & CRRT
                 • Biomarkers for Management of Critically Ill Patients • Special Pre-Conference AKI Symposium and CRRT Workshop

                           Conference Secretariat:                                     All Attendees receive access to the conference’s
                           RES Seminars                                        on-demand recordings for 90 days AND can participate
                           4425 Cass Street, Suite A                           in both the AKI Symposium & CRRT Workshop!
                           San Diego, CA 92109 USA                             Our Virtual Platform enables great networking
                           Email: crrt@res-inc.com                             opportunities and live communications!
                           Tel: 1-858-272-1018 Fax: 1-858-272-7687
                                                             For more information visit:
                                                             crrtonline.com

F20149
12TH CONGRESS OF THE VASCULAR
ACCESS SOCIETY

April 6–9, 2021, www.vas2021.org

�e biannual Vascular Access Society (VAS) Congress is the most important international meeting for vascular access
experts – vascular surgeons, interventional radiologists, nephrologists, dialysis nurses and technicians… – simply for all
who take care of dialysis access patients.

WE GO VIRTUAL
Since the COVID-19 pandemic is going on with traveling restrictions and rules for social distancing we are not able to run a congress
with presence in Berlin. Your safety is our highest priority.

SCIENTIFIC PROGRAM COMMITTEE
Christian Hohl – chairman of the organizing committee

Michael Burbelko                   Markus Hollenbeck                 Jan Malik                          Joris Rotmans
Maurizio Gallieni                  Jose Ibeas                        Vladimir Matoussevitch             Robert Shahverdyan
James Gilbert                      Ruben Iglesias                    Norton de Matos                    David Shemesh
Paul Gibbs                         Tamara Jemcov                     Kathleen Rickert                   Matteo Tozzi

SESSION TOPICS
Endovascular vs. Surgical fistula creation                            Endovascular techniques
What is the best access: Fistula, gra� or catheter?                  Cardiovascular effects of hemodialysis access
PD catheters                                                         Central venous catheters for hemodialysis access
Maturation – Expert case discussion                                  Outcome of vascular access
Recent clinical trials                                               Doppler Ultrsound by nurses
Guidelines                                                           Cannulation techniques
Vascular access centers                                              Care protocols of fistulae
Vascular access overview                                             Video session
Dedicated devices for vascular access                                My worst case
Central vein occlusive disease
                                                                                                                                        EA21001

PRE-CONGRESS HANDS-ON WORKSHOP FOR PHYSICIANS
Ultrasound                                                           Surgical procedures
Interventional Procedures incl. Fistula creation                     Catheters
                                                                                                                               ! EW

PRE-CONGRESS HANDS-ON WORKSHOP FOR NURSES
                                                                                                                             TE E N
                                                                                                                           DA TH

Arteriovenous fistula evaluation through physical examination         Ultrasound guided cannulation
Vascular Access Ultrasound                                           CVC – Handling and implantation
                                                                                                                      VE
                                                                                                                    SA
58
                                                                     TH

                                          ERA-EDTA
                                         CONGRESS
                                      berliN, GERMANY
                                                   JUNE 5-8, 2021
              Live in Berlin or Virtual,
          whatever you choose, together we will
             shape the future of nephrology
                Registrations are open!
                   Check out the full details:
                 www.era-edta.org/en/berlin2021/

                                                             www.era-edta.org
EA21002
The leading non-society journal

                                                                                                                                     Highlights in this issue:
                                                                                                                                  Genome-Wide Association Study of Renal Function Traits: Results
                                                                                                                                   from the Japan Multi-Institutional Collaborative Cohort Study
                                                                                                                                     Hishida, A.; Nakatochi, M.; Akiyama, M.; Kamatani, Y.; Nishiyama, T.; Ito, H.;
                                                                                                                                     Oze, I.; Nishida, Y.; Hara, M.; Takashima, N.; Turin, T.C.; Watanabe, M.; Suzuki, S.;
                                                                                                                                     Ibusuki, R.; Shimoshikiryo, I.; Nakamura, Y.; Mikami, H.; Ikezaki, H.; Furusyo, N.;

Editor-in-Chief               Associate Editors                                                                                      Kuriki, K.; Endoh, K.; Koyama, T.; Matsui, D.; Uemura, H.; Arisawa, K.; Sasakabe, T.; Okada, R.;
                                                                                                                                     Kawai, S.; Naito, M.; Momozawa, Y.; Kubo,M.; Wakai, K.; The Japan
                                                                                                                                     Multi-Institutional Collaborative Cohort (J-MICC) Study Group

G.L. Bakris,                  R. Agarwal,                    S. Sprague,                                                          Dietary Changes Involving Bifidobacterium longum and
                                                                                                                                   Other Nutrients Delays Chronic Kidney Disease Progression
                                                                                                                                     Iwashita, Y.; Ohya, M.; Yashiro, M.; Sonou, T.; Kawakami, K.; Nakashima, Y.; Yano, T.; Iwashita,

 Chicago, IL                    Indianapolis, IN               Evanston, IL
                                                                                                                                     Y.; Mima, T.; Negi, S.; Kubo, K.; Tomoda, K.; Odamaki, T.; Shigematsu, T.

                                                                                                                                  A Randomized Clinical Trial of Metformin to Treat Autosomal
                                                                                                                                   Dominant Polycystic Kidney Disease

                              R.J. Glassock,                 M.R. Weir,
                                                                                                                                     Seliger, S.L.; Abebe, K.Z.; Hallows, K.R.; Miskulin, D.C.; Perrone, R.D.; Watnick, T.;
                                                                                                                                     Bae, K.T.

                                Los Angeles, CA                Baltimore, MD                                                         Affiliated with

                              B. Palmer,
                                Dallas, TX

The American Journal of Nephrology is a peer-reviewed journal that fo-       Selected contributions
cuses on timely topics in both basic science and clinical research. Papers   • Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative
are divided into several sections, including:                                  Review: Wanchoo, R. (Great Neck, NY); Karam, S. (Beirut); Uppal, N.N.;
• Original reports, spanning clinical, basic and outcomes research            Barta, V.S. (Great Neck, NY); Deray, G. (Paris); Devoe, C. (New Hyde Park, NY);
                                                                              Launay-Vacher, V. (Paris); Jhaveri, K.D. (Great Neck, NY) on behalf of Cancer and
• In-depth topic reviews on specific topics selected by the Editor and        Kidney International Network Workgroup on Immune Checkpoint Inhibitors
  Associate Editors                                                          • Distinct in vitro Complement Activation by Various Intravenous Iron
• Invited debates – selected on ‘hot topics’ determined by the editorial       Preparations: Hempel, J.C.; Poppelaars, F.; Gaya da Costa, M.;
  board                                                                       Franssen, C.F.M.; de Vlaam, T.P.G. (Groningen); Daha, M.R. (Groningen/Leiden);
Responding to the ever increasing pace in research, the American Jour-        Berger, S.P.; Seelen, M.A.J.; Gaillard, C.A.J.M. (Groningen)
nal of Nephrology adheres to a very tight publication schedule: accept-      • Association of Serum Potassium with All-Cause Mortality in Patients with
ed papers appear online within 5–6 weeks of acceptance.                        and without Heart Failure, Chronic Kidney Disease, and/or Diabetes:
                                                                              Collins, A.J. (Minneapolis, MN); Pitt, B. (Ann Arbor, MI); Reaven, N.; Funk, S.
                                                                              (La Canada, CA); McGaughey, K.; Wilson, D. (Redwood City, CA); Bushinsky, D.A.
                                                                              (Rochester, NY)
                                                                             • Elevated Serum Uric Acid Level Predicts Rapid Decline in Kidney
                                                                               Function: Kuwabara, M. (Denver, CO/Tokyo); Bjornstad, P. (Denver, CO/
                                                                              Aurora, CO); Hisatome, I. (Yonago); Niwa, K. (Tokyo); Roncal-Jimenez, C.A.;
American Journal of Nephrology                                                Andres-Hernando, A.; Jensen, T.; Milagres, T.; Sato, Y.; Garcia, G. (Denver, CO);
                                                                              Ohno, M. (Tokyo); Lanaspa, M.A.; Johnson, R.J. (Denver, CO)
Founded: 1981
                                                                             • Targeting Hypoxia-Inducible Factors for the Treatment of Anemia in
Category: Clinical and Basic Research
                                                                               Chronic Kidney Disease Patients: Locatelli, F. (Lecco); Fishbane, S.
Field of Interest: Nephrology                                                 (Great Neck, NY); Block, G.A. (Denver, CO); Macdougall, I.C. (London)
Listed in bibliographic services, including:                                 • Effects of Daprodustat, a Novel Hypoxia-Inducible Factor Prolyl
PubMed/MEDLINE, Web of Science, Google Scholar,                                Hydroxylase Inhibitor on Anemia Management in Japanese Hemodialysis
Scopus, Embase                                                                 Subjects: Akizawa, T. (Tokyo); Tsubakihara, Y. (Osaka); Nangaku, M.; Endo, Y.;
                                                                              Nakajima, H.; Kohno, T.; Imai, Y.; Kawase, N.; Hara, K. (Tokyo); Lepore, J.;
2019: Volumes 49, 50                                                          Cobitz, A. (Collegeville, PA)
6 issues per volume                                                          • Vitamin K Metabolism in a Rat Model of Chronic Kidney Disease:
                                                                              McCabe, K.M. (Kingston, ON); Booth, S.L.; Fu, X. (Boston, MA); Ward, E.;
Language: English
                                                                              Adams, M.A.; Holden, R.M. (Kingston, ON)
ISSN 0250–8095
e-ISSN 1421–9670
                                                                                                                                                                                                                                        KF 19003

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