Summary STATE COORDINATION PROGRAM - for the Development of Biotechnology in the Russian Federation until 2020

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Summary STATE COORDINATION PROGRAM - for the Development of Biotechnology in the Russian Federation until 2020
GOVERNMENT                                         Lomonosov
OF THE RUSSIAN   Ministry of Economic Development   Moscow State
  FEDERATION
     ______          of the Russian Federation      University
     2012

Summary
STATE COORDINATION PROGRAM
for the Development of Biotechnology
in the Russian Federation until 2020
“BIO 2020”
Summary STATE COORDINATION PROGRAM - for the Development of Biotechnology in the Russian Federation until 2020
Summary STATE COORDINATION PROGRAM - for the Development of Biotechnology in the Russian Federation until 2020
STATE
COORDINATION
PROGRAM
for the Development of Biotechnology
in the Russian Federation
until 2020
“BIO 2020”
Summary STATE COORDINATION PROGRAM - for the Development of Biotechnology in the Russian Federation until 2020
Summary
          The 21st century is rightly considered the time of life sciences when bio-
    technologies start to play a more significant role in the environmental protection,
    the design of new materials, an increase in the agricultural productivity and the
    improvement of life quality in general. The world is gradually moving toward a new
    economic structure based upon the usage of renewable resources, to the develop-
    ment of bioeconomics.

          According to the OECD, by 2030 biotechnologies will be used in

35 50 80
                       %                                    %                                      %

of chemical industry                 of agricultural production                         of drugs
      products

          In general biotechnology products will constitute up to 2.7% of global gross
    domestic product of developed countries, and for developing countries, among which
    the Russian Federation, this percentage will be even higher.

          The Russian Federation possesses unique natural resources, almost unlimited
    reserves of renewable vegetable raw materials, large reserves of fresh water, fertile
    arable lands, qualified human resources and recognized scientific schools and should
    not stand aside from around the world process.

          The necessity of providing the sustainable social and national economy de-
    velopment for the long-term perspective, risk of loss of traditional sale markets and
    devaluation of main export products on world markets as a result of the replacement
    by products based on renewable raw material, insistently demands the development
    of the biotechnological complex of the country.

          In the recent past a number of instruments supporting the development of
    biotechnology have been employed in Russia: there were approved The Strategy of
    Development of the Pharmaceutical Industry of the Russian Federation until 2020,
    The Strategy of Development of the Forest Complex of the Russian Federation until
    2020 and there was accepted the Federal Target Program “Development of the Phar-
    maceutical and Medical Industries of the Russian Federation until 2020 and Further
    Perspective”. The Strategy of Development of the Medical Industry of the Russian
    Federation until 2020 is being worked out. Separate aspects of fundamental and
Summary STATE COORDINATION PROGRAM - for the Development of Biotechnology in the Russian Federation until 2020
industrial biotechnology are being developed within a number of Federal Target pro-
grams. The biotechnological subject is actively supported by the Russian Foundation
for Basic Research and by research programs of the Russian Academy of Sciences
(RAS), the Russian Academy of Medical Sciences (RAMS) and the Rosselkhozacademy
(Russian Agricultural Academy). Applied and innovative projects are financed by the
Fund for Assistance to Small Innovative Enterprises in Scientific and Technical Area,
JSC “RUSNANO”, JSC “RVC”. Regional programs for the development of biotechnology
are being implemented.

      Three technological platforms for biotechnology were formed: “Medicine
of the Future”, “Bioindustry and Bioresources – BioTech2030” and “Bioenergetics”,
aimed at uniting and harmonizing interests of the state, scientific and business com-
munities in the creation of bioeconomics in the Russian Federation.

      Nevertheless, the analysis of the state-of-the-art of biotechnology in the
world and Russia showed that the development of biotechnological industry and
the leading of research and industrial production in this area to the global level of
competition require the right mix of targeted government policy. As a result in ac-
cordance with the decision of the Government Commission on High Technology and
Innovation there was developed and accepted the State Coordination Program for
the Development of Biotechnology in the Russian Federation until 2020.

     ▼ Altai, Russia
Aim of the Program:
       To bring Russia to the leading positions in the development of biotechnology,
including certain areas of biomedicine, agrobiotechnology, industrial biotechnology
and bioenergetics and creation of the globally competitive sector of bioeconomics,
which along with nanoindustry and information technologies, should become the
basis for modernization and creation of post-industrial economics.

       By 2015 – the development of domestic demand and export of biotechno-
logical products; the creation of the production and technological basis for new
sub-branches of industry enabling the replacement, in a long-term perspective, of a
significant part of products manufactured by chemical synthesis by products of bio-
logical synthesis; the creation of the technological and experimental and industrial
basis for biofuel industry.

       By 2020 – the formation of institutional prerequisites for the profound
modernization of the technological basis of the corresponding branches of industry
through mass implementation of methods and products of biotechnology in the pro-
duction; the integration of scientific and technological sector of Russia in the inter-
national system of knowledge production with the advancement to leading develop-
ment of scientific potential aimed at creating knowledge and technologies ensuring,
along with nanotechnologies and information technologies, the modernization of
industrial sector.

    ▲ Taiga, Russia
Terms of the Program implementation:
2012-2020.

Program coordinator:
Ministry of Economic Development of the Russian Federation

Main Program participants:
•   Federal bodies of executive power, senior executives of the Program in main sectors:
    — Ministry of Education and Science of the Russian Federation
    — Ministry of Industry and Trade of the Russian Federation
    — Ministry of Agriculture of the Russian Federation
    — Ministry of Natural Resources and Environmental Protection of the Russian Federation
    — Ministry of Healthcare of the Russian Federation
    — Ministry of Energy of the Russian Federation
    — Ministry of Regional Development of the Russian Federation
    — Federal Forestry Agency (Rosleskhoz) of Russia
    — Federal Fishery Agency of Russia
•   Involved bodies of executive power of constituent territories of the Russian Federation
•   Russian Academy of Sciences
•   Russian Academy of Medical Sciences
•   Russian Agricultural Academy
•   Russian Technology Platforms
    — «Bioindustry and Bioresourses – BioTech2030»
    — «Bioenergetics»
    — «Medicine of the Future»
•   Organizations – coordinators of technological platforms
•   Development institutions
•   other scientific organizations in the biotechnology sector.
Tasks of the Program:
•   Creation of the infrastructure for the development of biotechnology in Russia;

•   Formation and implementation of priority innovative and investment projects
    in biotechnology;

•   Large-scale development of bio-industry in the regions of Russia in all
    biotechnology sectors;

•   Support of the development of life sciences and physicochemical biology;

•   Creation of up-to-date educational programs and a system of human resource
    training in biotechnology;

•   Maintenance and development of bio-resource potential of the Russian
    Federation as the basis of bio-industry;

•   Solution of topical social and economic, power, environmental and other
    problems of the country by methods and means of biotechnology;

•   Integration of domestic biotechnology in the world bioeconomics;

•   Improvement of legal, economic, informational and organizational basis
    for the development of biotechnology.

Expected results
of the Program implementation:
•   Increase in the volumes of production and consumption of biotechnological
products in the Russian Federation;

•     Advancement to the level of biotechnology production in Russia of about 1% of
global gross domestic product (GDP) by 2020 and the creation of conditions for the
rise of GDP by at least 3% by 2030;

•    Rapid improvement of the efficacy of the medical treatment due to the wide
spread of new methods of diagnostics and practice of personalized medicine;

•   Development of efficient methods for elimination of pollutants and reduction of
adverse anthropogenic impacts on the environment;

•    Increase in the food safety of the country due to implementation of biotechnol-
ogy in the field of agriculture;

•    Appearance of new available sources of energy due to the development of
bioenergetics.
▲ Lake Baikal, Russia
Plan of the Program implementation

      Goal    Development of domestic demand and export of biotechnological
     of the   products. (2012-2015)
     stage

     Tasks    1. Formation of a system of assistance to the promotion of bio-in-
     of the      dustry products in domestic and foreign markets.
     stage    2. Development and implementation of effective policies for stimulat-
                 ing the localization of manufacturing of part of biotechnological
                 production of foreign companies in Russia.

              3. Increase in the efficiency of mechanisms for commercialization
                 of research and design results in the field of biotechnology.

              4. Creation of the complete structure of bioeconomics in Russia,
                 including pilot, experimental, industrial enterprises, engineering
                 companies and centers for the development of technologies for
                 the application of biotechnological products.

              5. Creation of strategies to ensure significant growth in production
                 volumes of electricity and warmth as a result of mass implemen-
                 tation of modern bioenergetic devices.

              6. Appearance of a motivated circle of industrial companies in stra-
                 tegic branches, being able to become leaders in implementation
                 of new technologies.

              7. Creation of organizational and legal basis for the formation
                 of new markets of biotechnological products.

              8. Creation of a system of voluntary environmental certification.

              9. Creation of conditions for the stable functioning and development
                 of a system of training, retraining and keeping of human resources.

              10. Development of regional biotechnology programs and bio-clusters
                 in a number of constituent territories of the Russian Federation.

              11. Inventory of biological collections of the Russian Federation and
                 the formation of basic bio-resources centers of federal significance.

      Main    1. Formation of bioeconomics infrastructure.
investment    2. Creation of scientific and technological basis for biotechnology.
 directions
Goal    Creation of institutional conditions for profound modernization of the
     of the   technological basis through mass implementation of methods and prod-
     stage    ucts of biotechnology in the production. (2016-2020)

     Tasks    1. Creation of the production and technological basis for all main types
     of the      of industrial biotechnology products.
     stage    2. Creation of the industrial basis for the development of bioenerget-
                 ics, including production of electricity and warmth from biomass,
                 production of biofuel.

              3. Formation of a complex interdisciplinary system of research and
                 development, deeply integrated into international technological en-
                 vironment.

              4. Improvement of mechanisms for the support of innovative entre-
                 preneur aimed at attracting the potential of potential of research
                 institutions to create and produce new biotechnology products.

      Main    1. Development of new productions and expansion of production facili-
investment       ties on emerging markets.
 directions   2. Financing of programs for the mass introduction of products and
                 technologies in a wide range of industrial branches.
Financial guarantee
of the program implementation
       Financial guarantee of the Program will be provided by the Federal budget,
budgets of constituent territories of the Russian Federation, local budgets and also
off-budget financing.

       The I stage of the Program implementation will be funded by the Federal
budget, budgets of constituent territories of the Russian Federation, state institu-
tions of development, state corporations and companies with state share, large and
middle business. A significant part of investments may be attracted from interna-
tional corporations interested in localization of production facilities in Russia, part
of financing will be obtained from Russian and international capital markets.

       The main financial source of the II stage of the Program will be obtained
from funds of Russian and international corporations, financial means of enterprises
of middle and small business, financial means of state development institutions
and also investments from the fund market.

    Estimated financing needs for the period
              2011-2020, bln.rub*
Biopharmaceutics;                                                         Medicine;

106                                                                       150
Marine
biotechnology;                                                            Agricultural and
                                                                          food biotechnology;
70                                                                        200
Forest                                                                    Industrial
biotechnology;                                                            biotechnology;

45                                                                        210
Environmental                                                             Bioenergetics;
biotechnology;
                                                                          367
30
    ________
    *1$ = 32,086 Rub according to Central Bank of Russia on May, 30, 2012
Integral indicators of the
 Program tasks implementation

         35
Bln.$

         30                                                      31.17

         25

         20
                                     12.47                                24.93
         15

         10
                                             6.23
                3.74
          5
                 0.75
          0
  Year        2010                   2015                                2020

          Biotechnology production            Biotechnology production
          consumption amount                  amount

         90
         80
%

                     80
                                        60
         70
         60
                                                                          40
         50
         40
         30                             20

         20
         10                                                               25
                     1
          0
  Year        2010                   2015                                2020

          Quota of import                     Quota of export in production
          in consumption
Main instruments of biotechnology develop-
ment support
1.   Stimulation of demand for biotechnological products

2.   Assistance for increasing competitiveness of biotechnological enterprises

3.   Development of education in the field of biotechnology

4.   Development of science in the field of biotechnology

5.   Development of experimental production base

6.   Support and development of biocollections

7.   Cooperation of business, science and education

8.   Support of biotechnology in regions

9.   International cooperation

10. Formation of information and analytical infrastructure of biotechnologies
Priority of biotechnology
 development
        In addition to main instruments of the Program implementation present-
 ing “horizontal” measures of the development of biotechnology sector, the Program
 includes “vertical” measures in the main directions of biotechnology development
 united by the common theme of the relevant industry results.

        Taking into account the available scientific basis and tendencies, current situ-
 ation, the potential of market development and social and economic effect there are
 the following priorities of biotechnologies:

 •   Biopharmaceutics and biomedicine;

 •   Industrial biotechnology and bioenergetics;

 •   Agricultural and food biotechnology;

 •   Forest biotechnology;

 •   Environmental protection biotechnology;

 •   Marine biotechnology.

        Within the scope of the above priorities, complexes of events are formed inter-
 related and coordinated in time, resources and executors, which include research,
 development and engineering, material and technical support, human resources, in-
 formational, legal and economical support. Each of the main priorities of biotechnol-
 ogy implementation has federal bodies of executive power responsible for the state
 policy development in this field.

◄ Lake Teletskoye, Russia
Priority        (responsible)            Complex of measures

Biopharmaceutics.                        1. Vitally important drugs (biogenerics, hormones,
                                            cytokines, therapeutic monoclonal antibodies,
Serves for the transition to innova-
                                            peptides, phytomedicines and other).
tion model of pharmaceutical in-
dustry development in the Russian        2. New generation vaccines.
Federation
                                         3. Antibiotics and bacteriophages.
(Ministry of Industry and Trade
of the Russian Federation)

Biomedicine.                             1. In vitro diagnosticums (medical tests performed
                                            in a controlled environment outside of a living
Includes complexes of events
                                            organism).
aimed on the design of modern diag-
nostic devices (biochips, biosensors),   2. Personalized medicine.
biocompatible materials, develop-
                                         3. Cellular and biomedical technologies.
ment of personalized medicine, and
also measures on the development of      4. Biocompatible materials.
cellular technologies.                   5. Systems medicine and bioinformatics.
(Ministry of Healthcare of the Rus-      6. Development of biological sample banks. Infra-
sian Federation)                            structure support of research on animals.

Industrial biotechnology.                1. Enzyme production.
Creation in Russia of large-scale bio-   2. Biotechnological production of amino acids.
technology industry supplying basic
                                         3. Organization of production of glucose-fructose syrups.
economic sectors with raw materials
and half-finished products.              4. Production of polysaccharides.

(Ministry of Industry and Trade          5. Production of antibiotic substances.
of the Russian Federation)               6. Production of biodegradable polymers.
                                         7. Development of biotechnological complexes of
                                            deep processing of wood biomass.
                                         8. Transition of chemical industry plants on renew-
                                            able raw materials.
                                         9. Application of biogeotechnology in mining industry.
                                         10. Deep processing of grain and other agricultural
                                             plants.
                                         11. Development of biorefining principles based on
                                             cellulose production.
                                         12. Biofuel production base on wood waste.
                                         13. Production of larvicidal preparations.
Priority        (responsible)       Complex of measures

Bioenergetics.                      1. Electric power and warmth production from biomass.
Development of new techno-          2. Absorption (utilization) of greenhouse gases formed
logical approaches and the pro-        in power production cycles, industrial and communal
duction basis in bioenergetics.        waste water for the intensification of production of
                                       non-food biomass.
(Ministry of Energy of the Rus-
sian Federation, Ministry of        3. Reduction and elimination of adverse anthropogenic
Natural Resources and Envi-            impacts on the environment caused by electric power
ronmental Protection of the            industry by means of bioconversion.
Russian Federation, Ministry
                                    4. Bioenergy engineering.
of Agriculture of the Russian
Federation, Ministry of Indus-      5. Production of biofuel and its components from biomass
try and Trade of the Russian           with specified hematological properties.
Federation)                         6. Industrial production of non-food biomass for fuel and
                                       energy resources including selection technologies and
                                       bioengineering methods.
                                    7. Energy utilization of waste.

Agricultural                        1. Biological plant protection.
biotechnology.
                                    2. Types of plants produced by means of biotechnology.
Sustainable development of
                                    3. Technology of molecular selection of animals and birds.
agricultural production, solu-
tion of the food safety problem,    4. Transgenic and cloned animals.
production of high-quality          5. Biotechnology of soils and biofertilizers.
environmentally safe food,
processing of agricultural          6. Biopreparations for cattle breeding.
waste, soil fertility restoration   7. Feed proteins.
(Ministry of Agriculture of the     8. Processing of agricultural wastes.
Russian Federation)
                                    9. Biological components of fodders and premixes.

Food biotechnology.                 1. Dietary proteins.
(Ministry of Agriculture of the     2. Enzyme preparations.
Russian Federation)
                                    3. Prebiotics, probiotics, synbiotics.
                                    4. Functional food products including medical, preventive
                                       and baby.
                                    5. Food ingredients, including vitamins and functional
                                       mixes.
                                    6. Deep processing of raw food materials.
Priority       (responsible)      Complex of measures

Forest biotechnology.             1. Application of biotechnology for forest plantation man-
                                     agement.
(Federal Forestry Agency (Ros-
leskhoz) of Russia)               2. Application of biotechnology for conservation and
                                     renovation of forest genetic resources.
                                  3. Production of biotech trees with desired features.
                                  4. Biological means of forest protection.

Environmental                     1. Bioremediation.
biotechnology.
                                  2. Environmentally safe housing.
(Ministry of Natural Resources
                                  3. Biological collections and bio resource centers.
and Environmental Protection
of the Russian Federation, Min-
istry of Regional Development
of the Russian Federation, Min-
istry of Education and Science
of the Russian Federation)

Marine biotechnology              1. Formation of a network of aqua bio centers.
(Federal Fishery Agency           2. Deep processing of marketable hydrobionts and aquac-
of Russia)                           ulture production.
                                  3. Special forage for aquacultures.
The approval by V.V. Putin of the State Coordination
Program for the Development of Biotechnology in the Rus-
sian Federation until 2020 reflects a profound understanding
of the existing situation, defines biotechnology as one of pri-
ority areas of economic development of the Russian Federa-
tion and expresses the decision of the country government
to support this area at the state level. The implementation of
the targeted state policy in this field should contribute to the
complex development of the corresponding sectors of biotech-
nology, the creation of domestic demand for biotechnological
products and extension of their assortment, modernization of
existing productions, creation of new technologies, training of
highly skilled personnel and attraction of foreign biotechnology
companies to organization of production and movement of part
of research to Russia. All this undoubtedly will lead to intensi-
fication of the sector development in general and transition the
country to leading positions in the world in this field.
GOVERNMENT
OF THE RUSSIAN           Ministry of Economic Development
  FEDERATION
     ______                  of the Russian Federation
      2012

                                         Lomonosov Moscow
                                         State University

 Main participants of the development of “BIO2020” were three
 Russian Technology Platforms: “Bioindustry and Bioresources –
 BioTech2030”, “Bioenergetics” and “Medicine of the Future”.

 The work under the Program “BIO2020” was held with the par-
 ticipation of leading experts in biotechnology: representatives
 of federal bodies of executive power, scientific, educational and
 business communities. The Program was approved by the Chair-
 man of the Government of the Russian Federation V.V. Putin on
 April 24, 2012.

 Russian Technology Platform “BioTech2030”
 www.biotech2030.ru
 +7(495)648 0927
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