The 2021 Fresco International Workshop on Synaptic Plasticity and Advances in Parkinson's Disease

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The 2021 Fresco International Workshop on Synaptic Plasticity and Advances in Parkinson's Disease
NYU Grossman School of Medicine
Continuing Medical Education

The 2021 Fresco International
Workshop on Synaptic
Plasticity and Advances
in Parkinson’s Disease
Tuesday–Friday, October 12–15, 2021

Florence, Italy
nyulmc.org/frescocme

       Endorsed by the International Parkinson and Movement Disorder Society, the Parkinson’s
   Foundation, the LIMPE-DISMOV Academy, the Italian Society for Neuroscience, the Societa Italiana
      di Neurofisiologia Clinica, and the Societa Italiana di Psicofisiologia e Neuroscienze Cognitive
The 2021 Fresco International Workshop on Synaptic Plasticity and Advances in Parkinson's Disease
The 2021 Fresco International Workshop on
Synaptic Plasticity and Advances in Parkinson’s Disease

WORKSHOP DIRECTORS                                          other health care professionals working with patients
                                                            with Parkinson’s disease and related disorders as well
Angelo Quartarone, MD
                                                            as neuropsychiatric disorders
M. Felice Ghilardi, MD
Mark Hallett, MD
Monica Norcini, PharmD, PhD                                 MEETING APP
                                                            Meeting materials will be distributed electronically via
COURSE DIRECTORS                                            an app. Emails regarding the app will be sent beginning
Andrew S. Feigin, MD                                        two weeks prior to the meeting. You will be able to
Steven J. Frucht, MD                                        download the app and view the meeting materials in
Un Kang, MD                                                 advance, as well as on the day of the meeting. The app
Monica Norcini, PharmD, PhD                                 can also be viewed on a desktop or laptop. The meeting
                                                            presentations will be available for view/download/print
MEETING DESCRIPTION                                         the week of the meeting. The meeting app will remain
Join us in Florence, Italy for the Fresco meeting           available for one year after the meeting.
this October focusing on synaptic plasticity and
Parkinson’s disease. In the workshop, international         REGISTRATION
experts will provide an overview of the scientific          nyulmc.org/frescocme
advances on different aspects of brain plasticity from
                                                            After 12 pm on October 5, 2021 only onsite registration is
bench to bedside in health and movement disorders.          available, provided the meeting has not reached capacity.
On the last day, NYU Langone faculty will present           Onsite registrants will incur an additional $20 charge.
didactic lectures, providing an overview of advances        Registration is non-transferable.
in diagnosis and treatment of Parkinson’s disease
and related disorders. Participants will gain a deeper      EACCME® ACCREDITATION STATEMENT
understanding of brain function and its relevance                        The 2020 Fresco International Workshop
to diagnosis and treatment of Parkinson’s disease,                       on Synaptic Plasticity and Advances in
parkinsonisms, and movement disorders.                                   Parkinson’s Disease, Florence, Italy,
                                                                         12/10/2021–15/10/2021 has been
EDUCATIONAL OBJECTIVES
                                                            accredited by the European Accreditation Council for
After this activity, participants should be able to:        Continuing Medical Education (EACCME®) with 20
• Describe the mechanisms of plasticity and                 European CME credits (ECMEC®s). Each medical
  their relevance in the genesis and treatment              specialist should claim only those hours of credit that
  of symptoms of Parkinson’s disease and                    he/she actually spent in the educational activity.
  parkinsonisms                                             Through an agreement between the Union
• Evaluate the latest development in the deep brain         Européenne des Médecins Spécialistes and the
  stimulation treatment of Parkinson’s disease and          American Medical Association, physicians may
  dystonia                                                  convert EACCME® credits to an equivalent number of
• Assess the use of rehabilitation techniques in            AMA PRA Category 1 CreditsTM. Information on the
  parkinsonisms                                             process to convert EACCME® credit to AMA credit
                                                            can be found at www.ama-assn.org/educatio /earn-
• Integrate the latest technology in the diagnosis
                                                            credit-participation-international-activities.
  and treatment of patients with Parkinson’s disease,
  parkinsonisms, and other movement disorders               Live educational activities, occurring outside of
                                                            Canada, recognised by the UEMS-EACCME® for
• Identify non-motor problems in Parkinson’s
                                                            ECMEC®s are deemed to be Accredited Group
  disease and determine specific treatments
                                                            Learning Activities (Section 1) as defined by the
• Utilize different types of testing to their full          Maintenance of Certification Program of the Royal
  advantage and identify some of their limitations          College of Physicians and Surgeons of Canada.
  as well as benefits in assessing patients with            CCME® for CME accreditation of this event.
  Parkinson’s disease, parkinsonisms, and other
  movement disorders                                        ITALIAN ACCREDITATION STATEMENT
• Describe the role of glia activity in inflammation in     Total of 23 CME credits. Course code: 6633-317921.
  neurodegenerative disorders                               Accreditation for: Physician, Nurse, Physiotherapist,
• Recognize visual and speech changes associated            Occupational Therapist, Speech-Language Therapist
  with Parkinson’s Disease                                  and Psychologist.

TARGET AUDIENCE
Researchers, physicians, and other care providers in
the field of neurology, internal medicine, rehabilitation
medicine, neurosurgery psychiatry, geriatrics and
AGENDA

                                                       9:00 am   A New Anatomical Perspective
TUESDAY, OCTOBER 12, 2021
                                                                 on the Connections Between
1:00 pm     Registration                                         Basal Ganglia and Cerebellum:
1:45 pm     Welcome Remarks                                      Functional Implications
            Paolo Fresco                                         Angelo Quartarone, MD
            Robert I. Grossman, MD                               Cognition, Emotion, Autonomic
            Kenneth Langone                                      Function and Cerebellum
2:00 pm     Introduction to the Workshop                         Jeremy D. Schmahmann, MD
            M. Felice Ghilardi, MD                               Cerebellum Contribution
            Angelo Quartarone, MD                                to Pathophysiology of
2:10 pm     Opening Panel—COVID-19 and                           Movement Disorders
            Possible Link with Parkinson’s                       Hyder A. Jinnah, MD
            Disease and Parkinsonism:                            Coffee Break
            From Bench to Bedside
                                                                 Cerebellum and Plasticity:
            David Sulzer, PhD
                                                                 A Target for Non-Invasive
            K Ray Chaudhuri, MD
            Peter Schmidt, PhD
                                                                 Stimulation
            Elena Moro MD, PhD                                   John Rothwell, PhD
                                                                 Cerebellum and Plasticity:
SESSION I:                                                       A Target for Invasive Stimulation
From Emotion to Motion                                           Andres Lozano, MD, PhD
Moderators: Veronica Ghiglieri, PhD                             Panel Discussion
            Peter Schmidt, PhD                         12:30 pm Lunch and Poster Session
            Hartwig R. Siebner, MD, DMSci
3:00 pm     From Emotion to Motion: Cortical           SESSION III:
            and Subcortical Contributions              Parkinsonisms and Plasticity
            Edmund T. Rolls, MA, DPhil, DSc, Hon DSc
                                                       Moderators: P
                                                                    aolo Calabresi, MD
            Chronic Stress: From Neuronal                          Massimo Cincotta, MD
            Plasticity to Neurodegeneration                        Giacomo Koch, MD, PhD
            Sheela Vyas, MD                            2:30 pm   Rehabilitation in Parkinsonisms
            Coffee Break                                         Robert Iansek, PhD, FRACP
            Stress, Sex, and Plasticity                          Tau and the Cytoskeleton:
            Debra Bangasser, PhD                                 Relevance to Synaptic
            Functional Movement Disorders:                       Damage, Plasticity, and
            Maladaptive Plasticity in the                        Neurodegenerative Diseases
            Limbic-Motor Circuitry                               Francesca Bartolini, PhD
            Mark Hallett, MD                                     Tau and Plasticity
            Panel Discussion                                     Michael Rowan, PhD

6:30 pm     Adjourn                                              Clinical Spectrum of
                                                                 Parkinsonisms: New Frontiers
6:45 pm     Social Event: Cocktail
                                                                 Alessandro Di Rocco, MD
            & PD Art Exhibition
                                                                 Coffee Break
                                                                 Cortical Plasticity in
WEDNESDAY, OCTOBER 13, 2021                                      Corticobasal Syndrome,
8:30 am     CME Sign-In                                          PSP, MSA, and Lewy Body
                                                                 Antonio Suppa, MD, PhD
SESSION II:                                                      Panel Discussion
Cerebellum: New Perspectives
                                                       6:30 pm   Round Table: What Patients
in Movement Disorders
                                                                 Want from Research
Moderators: Matilde Inglese, MD, PhD                  7:00 pm   Adjourn
            Marco Molinari, MD, PhD
            Ulf Ziemann, PhD
AGENDA

                                                         Towards Adaptive DBS:
THURSDAY, OCTOBER 14, 2021
                                                         Retuning Gait Freezing
                                                         in Parkinson’s Disease
8:30 am    CME Sign-In
                                                         Ioannis Isaias, MD, PhD

SESSION IV:                                              The Present and the Future
Plasticity and Non-Motor Symptoms                        of FUS for Movement Disorders
in Parkinson’s Disease                                   Jose A. Obeso, MD, PhD

Moderators: Vicenzo Di Lazzaro, MD
                                                         Panel Discussion
            Simone Rossi, MD, PhD                        Final Remarks and Conclusion
            Mario Zappia, PhD                            Mark Hallett, MD
9:00 am    Fatigue in PD:                     6:00 pm    Adjourn
           A Plasticity-Related Disorder?
           K Ray Chaudhuri, MD
                                              FRIDAY, OCTOBER 15, 2021
           Vision and Plasticity
           in Parkinson’s Disease
                                              8:00 am    Welcome and Course Introduction
           M. Felice Ghilardi, MD
                                                         Steven L. Galetta, MD
           Pain as Maladaptive Plasticity
           in Parkinson’s Disease             SESSION I:
           Michele Tinazzi, MD, PhD           Genetic and Inflammation
           Coffee Break                       Moderator: Un Kang, MD
           Sleep Disorders in PD: An          8:10 am    Astrocytes in
           Ultimate Disorder of Plasticity?              Neurodegenerative Disorders
           Raffaele Ferri, MD                            Shane A. Liddelow, PhD
           Macrobioma and Parkinson’s                    Glial Targeted Therapy in
           Disease: Cause, Effect,                       Huntington’s Disease:
           or Mere Association?                          The SIGNAL Trial
           Gonzalo Torres, PhD                           Andrew S. Feigin, MD
           Panel Discussion                              Inflammation and Genetics
12:30 pm Lunch and Poster Session                        in Parkinson’s Disease
                                                         Giulietta M. Riboldi, MD, PhD
SESSION V:                                               Modeling Genetic Parkinson’s
Does DBS Modulate Plasticity in                          Disease in Patient-Derived
Parkinson’s Disease and Dystonia?                        Cell Systems
                                                         Emanuele Frattini, MD
Moderators: Giancarlo Comi, MD
            Leonardo Lopiano, MD, PhD                    Panel Discussion
            Elena Moro, MD, PhD
                                              SESSION II:
2:30 pm    The Past, the Present,
                                              Non-Motor Symptoms
           and the Future of DBS
                                              of Parkinson’s Disease
           Alim-Louis Benabid, MD, PhD
           Subcortical Deep Brain             Moderator: Andrew S. Feigin, MD
           Stimulation Modulates Cortical     9:35 am    Visual Perception Mechanisms
           Excitability and Plasticity                   Biyu J. He, PhD
           Robert Chen, MBBChir, MSc, FRCPC              Rehabilitative Potential of Artistic
           Motor Cortical Plasticity                     Experience in Patient with PD
           and Pathological Oscillatory                  Alberto Cucca, MD
           Activity in Dystonia                          Speech and DBS
           Diane Ruge, PhD                               Federica Avantaggiato, MD
           Coffee Break                                  Panel Discussion
                                                         Coffee Break
AGENDA

SESSION III:                                                                  Exercise Enhances DA Release and
Basic Mechanism of Plasticity                                                 BDNF Levels in Mouse Striatum
and Clinical Applications                                                     Guendalina Bastioli, PhD

Moderator: Richard Tsien, PhD
                                                                              Panel Discussion

11:00 am Keynote Speaker:                                        SESSION IV:
         Speech and Motor Learning                               Movement Disorders Video Rounds
              Michael A. Long, PhD
                                                                12:25 pm Video Rounds
              Dopamine Modulates the                                          Andrew S. Feigin, MD
              size of Striatal Projection                                     Steven J. Frucht, MD
              Neuron Ensembles                                                Un Kang, MD
              Marta Maltese, PhD                                              Mark Hallett, MD
              Enhancement of Axonal                             1:00 pm       Adjourn
              Dopamine Release by Leptin
              Maria Mancini, PhD
              GABA Co-Transmission from
              Dopaminergic Neurons as
              a Potential Candidate for
              Striatal Modulation
              Riccardo Melani, PhD

MEETING FEES                                                         Early Registration                            Regular
                                                                     (Ending on August 11, 2021 at 11:59 pm EST)

Young Investigators, Physicians, Researchers 40 years old                 $350                                          $410

Please note: This meeting is eligible for NYU Grossman School of Medicine Alumni discount.

REFUND POLICY                                                   CONTACT INFORMATION
Submit your request for a refund of meeting fees                NYU Grossman School of Medicine
more than $75 no later than 7 days before the                   Phone: 212-263-5295
meeting start date. No refunds will be issued for               Email: cme@nyulangone.org
cancellations or no-shows after that time.
To request a refund, email cme@nyulangone.org.                  ITALIAN CONTACT INFORMATION
A $75 administrative fee will be deducted.                      Fresco Parkinson Institute Italia
                                                                Phone: +39 055 598999
MEETING CANCELLATION POLICY                                     Email: info@frescoparkinsoninstitute.it
If a meeting is cancelled due to inclement weather,
insufficient enrollment, or any other reason, NYU
                                                                PROVIDED BY
Grossman School of Medicine will refund registration            NYU Grossman School of Medicine
fees in full. NYU Grossman School of Medicine will
provide at least two weeks’ advance notice if cancelling
due to insufficient enrollment and as soon as possible
                                                                ABSTRACT SUBMISSION
in all other circumstances. NYU Grossman School of              We are accepting abstract submissions for poster
Medicine is not responsible for any airfare, hotel, or          presentation highlighting your research findings
other non-cancellable costs incurred by the registrant.         possible on the topic of the five sessions.
                                                                Please submit your abstract with a maximum
LOCATION                                                        of 250 words excluding title, authors, and
Istituto degli Innocenti                                        presenters to: FI-NRP@nyulangone.org and
Piazza della Santissima Annunziata, 12                          monica.norcini@nyulangone.org.
50122 Firenze                                                   Poster Dimensions: 24" x 36" (61 x 91 cm).
                                                                Deadline for submission: September 14, 2021
                                                                The best abstract will be selected also for oral
                                                                presentation discussion.
Non-Profit Org.
                                                            U.S. Postage
                                                               PAID
The 2021 Fresco          NYU Grossman School of Medicine    New York, NY
                         550 First Avenue, MS1 195          Permit #8167
International Workshop   New York, NY 10016
on Synaptic Plasticity
and Advances in
Parkinson’s Disease

October 12–15, 2021
nyulmc.org/frescocme
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