2021/2022 Summer Research Program - Research Projects offered by Schools in the Faculty of Science - UQ Science Faculty

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2021/2022 Summer Research Program
Research Projects offered by Schools in the Faculty of Science

School of Agriculture and Food Sciences ...................................................................................... 2
School of Biological Sciences ....................................................................................................... 16
School of Chemistry and Molecular Biosciences......................................................................... 23
School of Earth and Environmental Sciences .............................................................................. 43
School of Mathematics and Physics ............................................................................................ 48
School of Veterinary Science ....................................................................................................... 74

How to apply
The UQ Summer Research Program is offered by a number of schools in the Faculty of
Science during the summer vacation period (mid-November to mid-February). This
document provides you with a list of available projects.
1) Browse the projects. You may select a School from the table of contents above to
   be taken directly to their listed research projects.
2) Contact a potential supervisor in the area of your interest, or the contact person
   listed, to discuss your interest to undertake their research project. Gain the
   research project supervisor’s tentative approval in writing and include this with
   your full UQ Summer Research program application.
3) Submit your application via StudentHub.

Faculty of Science, Summer Research Program, Project List 2021/2022 Last updated 10 September 2021
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School of Agriculture and Food Sciences

 Supervisor        A/Prof Brett Ferguson                               Duration: 6-10 weeks
 Contact           Email: b.ferguson1@uq.edu.au
 Details:
 Discovery and Characterisation of New Molecular Components Required for the
 Development and Control of Legume Nodules
 Nitrogen fertilizer use in agriculture is inefficient, costly and can be environmentally
 damaging. Legume crops represent an economically and environmentally sound alternative,
 as their relationship with nitrogen-fixing soil bacteria enables them to thrive in the absence
 of nitrogen fertilizer. The bacteria (commonly referred to as rhizobia) are housed in
 specialized root organs, called nodules. Identifying critical components of legume
 nodulation is now needed to optimise the process and improve agriculture sustainability
 and food security. This project aims to discover and functionally characterise novel
 molecular factors that act in the development and control of legume nodule numbers.
 Findings could enhance the current nodulation model and could help underpin future
 strategies to reduce the current over-reliance on nitrogen fertilizers in agriculture.
 Number of student places available: 2
 Delivery: Projects can be onsite (e.g. laboratory and glasshouse) or online (e.g. bioinformatic
 approaches using existing programs to identify new genes and domains)
 Expected outcomes: Students will gain skills in molecular signalling and plant physiology.
 Knowledge pertaining to various research techniques could include aspects of the following:
 qRT-PCR, gene cloning, transcriptomic analysis, bioinformatics, Agrobacterium-mediated
 transformation, gene over-expression, gene editing (CRISPR), promoter::reporter fusions,
 hormone quantification, new signal discovery, etc.
 Suitable for: An interest in plant science would be ideal, with individual projects that can be
 tailored to focus on research areas such as plant physiology, molecular signalling and
 development (genetic transformation and genome editing such as CRISPR, and plant-
 microbe interactions.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        Dr April Hastwell                                   Duration: 10 weeks
 Contact           Email: a.hastwell@uq.edu.au
 Details:
                   School of Agriculture and Legume Research
                   John Hines Building (62), Room 223A
                   St Lucia Campus
 Characterisation of peptides in legume root and nodule development
 There are a growing number of plant peptide families, with some having pivotal roles in
 development including root and shoot architecture; yield; as well as abiotic and biotic
 responses. While such peptides have been studied in the model species, Arabidopsis, they
 are not well characterised in crop species such as the legume, soybean. This is of interest as
 soybean can undergo two key agriculturally important beneficial symbiosis that Arabidopsis
 cannot. Legume nodulation is particularly significant as the process results in atmospheric
 nitrogen utilisation, rather than needing to add synthetic nitrogen fertilisers which are
 harmful to the environment.
 The project will use a range of physiological and molecular biology techniques to explore the
 role of peptides in legume nodulation and root development. Outcomes will enhance the
 molecular signalling models in these processes and provide the student with knowledge and
 skills useful for further studies in related areas.
 Number of student places available: 1
 Delivery: On-site attendance at St Lucia is required. The project can be completed via a
 remote working arrangement if needed due to COVID-19 restrictions.
 Expected outcomes: Students will gain an understanding of plant peptides and plant-
 microbe interactions. They may gain skills in plant molecular biology, bioinformatics, plant
 phenotyping and sample handling.
 Suitable for: Open to applications from students with a background in Plant Sciences.
 Students in Biochemistry and Molecular Biology; and Bioinformatics with an interest in
 plants are also encouraged to apply.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        Prof Susanne Schmidt                                  Duration: 10 weeks
 Contact           Email: Susanne.Schmidt@uq.edu.au
 Details:
 Advancing nutrient stewardship and the circular nutrient economy for a world without
 waste and pollution
 Evaluating plant performance with recycled nutrients and novel fertilisers based on
 biodegradable biopolymers
 Number of student places available: 2
 Delivery: With ‘business as usual’, we offer empirical research. Under COVID-19 restrictions,
 we offer projects based on existing data and scientific literature.
 Expected outcomes: Performing original research analysing experimental data and
 contributing to writing a scientific publication, research in lab, glasshouse or field. Gaining
 employability skills with teamwork, planning, conducting, analysing and communicating
 original research to peers, practitioners and industry partners.
 Suitable for: Students interested in plant and environmental sciences, but also those
 interested in interdisciplinary studies at the interface of engineering, economics, policy and
 legislation.
 Other important details: The projects have scope to be customised to student interests.
 Interested students must contact the supervisor/s, prior to submitting an application.
 Evidence of supervisor support is required to be uploaded as part of the application process.

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Supervisor        Prof Susanne Schmidt                                  Duration: 10 weeks
 Contact           Email: Susanne.Schmidt@uq.edu.au
 Details:
 Growing clean air
 Modelling and optimising the use of plant-based systems for indoor air quality
 Number of student places available: 2
 Delivery: With ‘business as usual’, we offer empirical research. Under COVID-19 restrictions,
 we offer projects based on existing data and scientific literature.
 Expected outcomes: Performing original research analysing experimental data and
 contributing to writing a scientific publication, research in lab, glasshouse or field. Gaining
 employability skills with teamwork, planning, conducting, analysing and communicating
 original research to peers, practitioners and industry partners.
 Suitable for: Students interested in plant and environmental sciences, but also those
 interested in interdisciplinary studies at the interface of engineering, economics, policy and
 legislation.
 Other important details: The projects have scope to be customised to student interests.
 Interested students must contact the supervisor/s, prior to submitting an application.
 Evidence of supervisor support is required to be uploaded as part of the application process.

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Supervisor        Prof Bhagirath Chauhan                              Duration: 10 weeks
 Contact           Email: b.chauhan@uq.edu.au
 Details:          Bld 8115, Room 209, Gatton
 Genetic diversity in turnip weed (Rapistrum rugosum)
 Turnip weed is becoming a problematic weed in the eastern region of Australia. A recent
 road trip showed that the weed is present along roadsides throughout the Darling Down
 areas. This project will evaluate the genetic diversity in this weed species. Genetic diversity
 is important for understanding the ability of weeds to adapt to different environments and
 the impact of herbicide selection on weed populations. DNA will be extracted from seeds or
 leaf tissues. The samples will be sent to AGRF for sequencing and results will be analysed by
 the student.
 The objective of the project is to characterize genetic variation in turnip weed biotypes
 collected from different maternal environments of Queensland.
 Number of student places available: 2
 Delivery: The Scholar will be required on-site at Gatton for the project.
 Expected outcomes: Scholars will gain experience in data collection and analysis. They will
 also gain skills in laboratory techniques.
 Suitable for: This project is open to students with a background in molecular biology (DNA
 extraction, PCR functions, etc.).
 Other important details: Interested students must contact the supervisor
 (b.chauhan@uq.edu.au) prior to submitting an application. Evidence of supervisor support is
 required to be uploaded as part of the application process.

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Supervisor        Prof Bhagirath Chauhan                              Duration: 10 weeks
 Contact           Email: b.chauhan@uq.edu.au
 Details:          Bld 8115, Room 209, Gatton
 Mapping and estimating weeds in chickpea
 Drones have emerged as an innovative technology to provide spatio-temporal information
 about weed species in crop fields. Such information is critical for any site-specific weed
 management program. This project will map and estimate weeds in chickpeas.
 Number of student places available: 3
 Delivery: The Scholar will be required on-site at Gatton for the project.
 Expected outcomes: Scholars will gain experience in mapping weeds in chickpea crops.
 Students will have the opportunity to write articles.
 Suitable for: This project is open to students with a background in computer science or
 engineering (need to work with drone images).
 Other important details: Interested students must contact the supervisor
 (b.chauhan@uq.edu.au) prior to submitting an application. Evidence of supervisor support is
 required to be uploaded as part of the application process.

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Supervisor        Dr Millicent Smith                                  Duration: 10 weeks
 Contact           Email: millicent.smith@uq.edu.au
 Details:
 Gaining new insight into mungbean physiology to increase yield potential and reliability
 Mungbean is an important cash and food crop grown in tropical and subtropical regions
 globally. Over the last three decades, the demand for mungbean has increased by over 60%
 and is now cultivated over 6 million hectares of land. Despite this increase in demand, the
 expansion of mungbean production is limited due to its low yield production and variability.
 A major reason for this is due to mungbean’s indeterminate reproductive behaviour which
 results in staggered maturity and the crop accumulating vegetation, flowers and pod
 components simultaneously. This behaviour has different implications for hand and
 mechanical harvesting systems. Other physiological components and behaviours have yet to
 be completely explored in mungbean (i.e. photosynthetic capacity), offering the opportunity
 to be exploited for increased crop productivity. This project aims to dissect the behaviour
 and genetics of a diverse mungbean population and to identify potential combinations of
 key agronomic traits that could be deployed to generate high yielding and reliable
 mungbean cultivars.
 The student will be assisting with two glasshouse experiments being undertaken
 simultaneously at St Lucia. The first experiment aims to collect detailed flower and pod
 development measurements to gain insight into how flowering behaviour influences yield
 potential and reliability. The second experiment aims to take detailed fluorometer
 measurements to determine whether the initial slope of the light response curve can be
 used to predict the maximum photosynthesis capacity of mungbean, which has yet to be
 done in any crop. Understanding these behaviours will contribute to identifying key genes
 of traits that are associated with high yields.
 Opportunities to be involved in field work at Gatton campus are also available to interested
 students.
 Number of student places available: 1
 Delivery: The project duration is 10 weeks, with hours of engagement being between 25-36
 hours per week. During these 10 weeks the applicant will be required to undertake the
 project on-site at the University of Queensland’s St Lucia campus.
 Expected outcomes: The student will gain an understanding of plant phenology and
 physiology, as well as the process of organising and managing glasshouse research
 experiments. They will gain skills in a range of data collection methods and will be able to
 undertake basic data analysis using the statistical program, R. The student will gain confidence
 with conducting glasshouse research activities and operating in a research environment.
 The scholar’s work has the potential to be incorporated into two manuscripts for peer-
 reviewed journal publications and will be a co-author on the paper/s. A short presentation
 will be required at the end of the project detailing their experience and their findings.
 Suitable for: This project is open to applicants from students with a science background.
 Students with some knowledge/interest in plant science are recommended for this project.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        Dr Alexandra Langford & Dr Scott Waldron            Duration: 10 weeks
 Contact           Email: Zannie.langford@uq.edu.au
 Details:
                   scott.waldron@uq.edu.au
 Improving rural seaweed farming livelihoods in Indonesia through improved drying oven
 designs
 In this project you will work with researchers involved with the Partnership for Australia-
 Indonesia Research (https://pair.australiaindonesiacentre.org/) on a project to improve the
 livelihoods of seaweed farmers in South Sulawesi, Indonesia.

 Background
 The Indonesian seaweed industry has rapidly expanded over the last twenty years and now
 supports the livelihoods of over 35,000 coastal households in South Sulawesi. The
 Government of Indonesia has prioritized the development of the seaweed industry as a
 result of its important role in poverty reduction in coastal communities.
 However, the industry suffers from a range of issues in production and processing. At the
 farmer level, seaweed farmers face challenges drying their seaweed. Substantial quality
 issues are introduced by poor drying practices, including drying on the ground (which can
 contaminate the seaweed with sand and other debris), high sun drying temperatures (which
 can destroy bioactive compounds), and insufficient drying resulting in high moisture
 contents. Farmers indicate that seaweed drying is one of the major challenges they face,
 particularly during the monsoon season, and as such there is an opportunity for technical
 interventions in this area to improve the efficiency of the industry and support more
 resilient and sustainable farmer livelihoods.

 Aim & Method
 This activity would investigate technologies for the development of a low temperature solar
 dryer for use in Indonesia to accelerate drying and improve seaweed quality through fast,
 low temperature drying. In this project, you will:
     1. Review academic and grey literature on drying technologies and prepare a report on
        the options available and their advantages and disadvantages.
     2. Design a simple survey for our local partners to distribute to seaweed farmers to
        understand their needs from drying technologies.
     3. Report on the findings of the two activities above and make suggestions for
        appropriate technology interventions. There may be an opportunity to publish the
        findings as a journal article depending on the outputs produced.
 Number of student places available: 2
 Delivery: Remote work arrangements available
 Expected outcomes: This project will provide experience analysing technical interventions
 for practical rural development applications, as well as in liaising (virtually) with local
 partners and developing a simple survey to assess seaweed farmer needs. A report based on
 the findings will be prepared and depending on the outputs produced, there may be an
 opportunity to co-author an academic article.
 Suitable for: This project is suitable for students with technical skills that would enable them
 to evaluate oven drying technologies. This could include students studying agribusiness,
 agricultural science, chemistry, chemical engineering, mechanical engineering or a related
 discipline. Students must have a technical background that enables them to review and

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analyse scientific articles. Desirable qualities include an interest in and knowledge of rural
 agricultural development issues.
 Other important details: Please contact Zannie Langford (zannie.langford@uq.edu.au) to
 discuss this role.
 Interested students must contact the supervisor/s, prior to submitting an application.
 Evidence of supervisor support is required to be uploaded as part of the application process.

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Supervisor        Dr Vivi Arief                                       Duration: 10 weeks
 Contact           Email: v.arief1@uq.edu.au
 Details:
 Effects of high temperature on growth and development of mungbean varieties
 High temperature stress on crop production is a global challenge. It is expected to become
 more frequent under future climate change. This predicted increase in temperature can
 have negative impact on growth and development and could decline in crop productivity. In
 this study, the responses to increased temperature on phenology, phenology and genetics
 will be quantified on selected mungbean varieties.
 Number of student places available: 1
 Delivery: The scholar will be required on-site at Gatton twice a week for 4 -5 weeks for data
 collection. Once the data has been collected, student can work form either St Lucia campus
 or Gatton campus or remote working arrangement can also be done, if required.
 Expected outcomes: Scholar may gain skill in physiology, agronomy and genetics. They will
 have an opportunity to generate publications from this research at the end of their project.
 Scholar may also be asked to produce a report or oral presentation at the end of their
 project.
 Suitable for: This project is open to applications from 2nd and 3rd year students with a
 background in crop physiology and agronomy.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        Mr Suresh Krishnasamy                              Duration: 6-10 weeks
 Contact           Email: suresh.krishnasamy@uq.edu.au
 Details:
                   School of Agriculture and Food Sciences
                   Gatton Campus Building 8117A - Room 314
 Systematic Review of Agriculture Education Teaching Practices
 Background: Teaching and learning is a key pillar at SAFS. With technology ever improving
 and knowledge in the field ever growing, we need to look constantly innovate our
 approaches to teaching to maintain our high standards by providing students with an
 evidence-based quality learning experience.
 Aim: The aim of the project is to conduct a systematic review of the literature to understand
 best practices around teaching and learning in agricultural education.
 Number of student places available: 2
 Delivery: The project will be for up to 10 weeks and the scholar will be required on-site at
 Gatton for up to 4 weeks during the project. Most of the work on the project can be done
 off-campus with different phases of the project requiring on-site attendance.
 Expected outcomes: Scholars will be involved in a systematic review exercise which is a
 fundamental skill in research. Scholars will get skills in how to perform literature searches,
 use research tools such as endnote and how to perform review of searched literature.
 Scholars will be expected to produce a study report. The scholar’s work will also be
 incorporated into a manuscript for peer-reviewed journal publication.
 Suitable for: This project is open to applications from students who have an interest in
 research.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        Mr Suresh Krishnasamy                             Duration: 6-10 weeks
 Contact           Email: suresh.krishnasamy@uq.edu.au
 Details:
                   School of Agriculture and Food Sciences
                   Gatton Campus Building 8117A - Room 314
 Biology Bridge
 Background: 1st year students taking biology have provided feedback regarding their
 experiences. Students who did not undertake high school biology reflected that they faced a
 challenge getting themselves up to speed and found themselves behind early on. However,
 who had prior knowledge of biology from high school found early course material at
 university repetitive from their high school experience and as a result felt disengaged.
 Aim: The aim of the project is to develop biology lesson modules that will be taken by future
 SAFS students who do not have prior experience in high school biology.
 Approach: The project will begin with a curriculum mapping exercise to map concepts
 covered in high school biology and year 1 biology courses at SAFS. This will be followed by
 the development of lesson packages and self-assessment activities. The final phase of the
 project will involve the deployment of the lesson packages and further study into its impact.
 Number of student places available: 2
 Delivery: The project will be for up to 10 weeks and the scholar will be required on-site at
 Gatton for up to 5 weeks during the project. Most of the work on the project can be done
 off-campus with different phases of the project requiring on-site attendance.
 Expected outcomes: Scholars will be involved in a curriculum mapping exercise and will gain
 skills in developing study materials (e.g., questionnaires, assessment questions), research
 methods as well as data collection and analysis. Scholars will be expected to produce a study
 report and develop a lesson bank including assessment exercises which will be used by
 future incoming students at SAFS. The scholar’s work will also be incorporated into a
 manuscript for peer-reviewed journal publication.
 Suitable for: This project is open to applications from students who have a background in
 high school biology and are interested in educational research.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        Dr Ammar Abdul Aziz                                  Duration: 10 weeks
 Contact           Email: a.abdulaziz@uq.edu.au
 Details:
                   Room 235, Building 8117A
                   Gatton campus
 Analysing the dynamics of rubber, maize or rice farming in southeast Asia using freely
 available satellite imagery
 (The crop will be determined in a discussion with the scholars)
 Our tiny research group at SAFS are working on a range of agribusiness research projects
 that involve modelling value chains and using remote sensing to analyse a range of aspects
 of agricultural activities. This project will involve conducting a systematic literature review
 (https://www.griffith.edu.au/griffith-sciences/school-environment-
 science/research/systematic-quantitative-literature-review) and the collection, processing
 and where possible the analysis of satellite imageries.
 Number of student places available: 2
 Delivery: The project can be conducted fully via a remote working arrangement. However, if
 condition permits, in person meetings would be conducted if required. Scholars will also
 need to attend the weekly research group zoom meeting.
 Expected outcomes: Scholars will develop their critical thinking skills through the systematic
 literature review exercise. They will gain skills in collection, processing and analysing freely
 available satellite images. Scholars will also have the opportunity to network with a group of
 PhD students working on a range of agribusiness topics. Scholars may have the opportunity
 to be involved in generating publications from their research which will be a component of
 something larger. Scholars may also be asked to produce an oral presentation at the end of
 their project.
 Suitable for: This project is suitable for undergrads in their final year or masters students.
 They will need to be curious and have a passion for learning something new.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        Dr Stephen Harper, Mr Johannes Biala, & Dr          Duration: 10 weeks
                   Alwyn Williams
 Contact           Dr Stephen Harper, s.harper1@uq.edu.au, Room 105, Bldg 8150, Gatton
 Details:          campus
                   Mr Johannes Biala, j.biala@uq.edu.au, Mob 0409062613
                   Dr Alwyn Williams, alwyn.williams@uq.edu.au, Tel 54601 617
 Characterization of high and low molecular weight humic substances from a range of
 organic materials at varying stages of decomposition
 The student will determine humic substance quantity and quality from various organic
 material sources at varying stages of decomposition through acid/alkali extraction. The data
 will be collated and analysed for the development of a humic index.
 Number of student places available: 1
 Delivery: The student will be required onsite at Gatton campus for most of the project
 duration.
 Expected outcomes: The student will be involved with organic chemistry within a field and
 laboratory setting, collecting samples and undertaking sample analysis to produce data for
 the development of a humic index and compost maturity calibration. The student will be
 asked to produce a report at the end of the project, which may result in the opportunity to
 publish the obtained results.
 Suitable for: This project is open to 3rd year Agricultural Science students. It is advantageous
 if the student has extensive laboratory experience and has worked within the realm of
 organic matter degradation / use of organic soil amendments / recycling of organic residues.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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School of Biological Sciences

 Supervisor        Dr Karen Cheney                                      Duration: 8 weeks
 Contact           Email: k.cheney@uq.edu.au
 Details:
                   Office: Goddard Building 118
 Colour perception in coral reef fishes
 Colour vision is essential for many animals to find food and mates, and avoid predation.
 However, the visual systems of most animals differ from that of humans. We therefore use
 visual modelling and behavioural experiments to understand how animals perceive objects
 in their environment. You will be trained in running behavioural experiments with coral reef
 fish to understand how fish perceive colour patterns.
 Number of student places available: 2
 Delivery: The Scholars will be required on-site at St Lucia for the project.
 Expected outcomes: The scholar will run behavioural experiment with coral reef fish and
 will gain experience in experimental design, data collection, visual modelling,
 spectrophotometry and animal husbandry. Previous scholars have had the opportunity to
 co-author a publication from summer research projects.
 Suitable for: This project is open to applications from students with interests in
 neurobiology, marine science, visual ecology, animal behaviour and/or fish biology.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        A/Prof Paul Ebert                                    Duration: 8 weeks
 Contact           Email: p.ebert@uq.edu.au
 Details:
                   3365 2973 (work)
                   Goddard room 374
 Worms on drugs
 Psychoactive drugs have effects on the genetic model organism, C. elegans, that reflect their
 effects on humans. This makes it possible to identify the genes that mediate the activity of
 the drugs. The specific drugs and genes that will be investigated will depend on the state of
 suitable projects when summer arrives, but could include fear, the reward pathway or the
 attention deficit drugs, amphetamine and methylphenidate.
 Number of student places available: 2
 Delivery: The Scholars will be required on-site at St Lucia for the project.
 Expected outcomes: This project will combine analysis of mutants and drugs using
 automated behavioural assays. When applied to a tiny, reproductively prolific, rapidly
 maturing organism like C. elegans, it is possible to generate a large number of robust
 behavioural assays over the span of the summer project. Data analysis and interpretation of
 results will be a significant component of the project.
 You will be working under the direct guidance of a postdoc as well as Honours and PhD
 students. You will be assisting with large scale screens that will help them to determine the
 most productive directions for their research.
 Students will be expected to maintain a research notebook, keep accurate records, process
 data into well-annotated graphs and present results at group meetings. In essence, you will
 be a full member of the research team
 Suitable for: 3rd level coursework experience with either genetics or neurobiology. Research
 lab experience will be beneficial.
 Students who have completed BIOL3222 or BIOL3380 are strongly encouraged to apply.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        A/Prof Jan Engelstaedter                            Duration: 8 weeks
 Contact           Email: j.engelstaedter@uq.edu.au
 Details:
 The mutational spectrum of antibiotic resistance
 Antibiotic resistance is a major problem in medicine and public health. Bacteria can become
 resistant through single mutations in genes whose products are targeted by the antibiotic.
 These mutations may differ in the rate at which they arise, the strength of resistance they
 confer, and their fitness consequences in the absence of drugs. In this project, the students
 will aim to characterise the complete mutational spectrum of antibiotic resistance to two
 important drugs, rifampicin and streptomycin, using the model organism Acinetobacter
 baylyi. Specifically, this will involve screening for resistant mutants, characterising these
 mutants at the genetic level by DNA sequencing, and characterising them phenotypically by
 measuring their fitness in presence and absence of drugs.
 Number of student places available: 2
 Delivery: Students will work in the lab for most of the time
 Expected outcomes: Students will gain experience in bacterial mutant screens, fitness
 assays, DNA extraction, PCR, electrophoresis, DNA sequencing, and bioinformatics.
 Suitable for: Open to all students with experience in handling of bacteria (sterile
 techniques) and a background in genetics (ideally BIOL1020 + BIOL2202)
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        Dr Simon Hart                                       Duration: 10 weeks
 Contact           Email: s.hart@uq.edu.au
 Details:
                   Office: Goddard Building (08), Room 220
 Effects of intraspecific variation and/or phenotypic plasticity on population persistence in
 response to extreme weather events
 Climate change is causing extreme weather events to become more frequent and intense.
 Because these events directly threaten species’ persistence, understanding the mechanisms
 by which species will respond is critical. Genetic variation within species and phenotypic
 plasticity allow species to respond to changes in environmental conditions and so may
 buffer the effects of extreme weather. The magnitude of these effects is, however,
 unknown. The aim of this project is to quantify the capacity of genetic variation and
 phenotypic plasticity on the persistence of freshwater plants subject to extreme weather.
 Findings will improve our ability to manage the capacity of species to respond to climate
 change and other rapidly developing threats.
 Number of student places available: 2
 Delivery: Attendance at UQ St Lucia campus is required
 Expected outcomes: Scholars will learn how to plan and run experiments in the laboratory
 and field, and to statistically analyse experimental data.
 I am optimistic that with good progress, this work will result in a peer-reviewed scientific
 publication, which is extremely important for career progress in science.
 Suitable for: Any student with an interest in how the natural world will respond to climate
 change.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        Dr Simon Hart                                       Duration: 10 weeks
 Contact           Email: s.hart@uq.edu.au
 Details:
                   Office: Goddard Building (08), Room 220
 Effects of intraspecific variation on tipping points in ecological systems
 When under pressure, ecological systems can cross thresholds that can lead to large and
 irreversible changes in ecosystem states. These changes are associated with dramatic
 declines in the population densities of some species and large changes in the structure and
 function of ecosystems. Thus, it is critically important to quantify the vulnerability of
 ecological systems to thresholds, to predict when thresholds will be crossed, and to
 understand if state changes can be reversed.
 This project will explore how genetic variation within populations affects tipping point
 behaviour in ecological systems. The project will require some background in mathematics
 and computer simulations. We can also discuss opportunities to do some experimental work
 in the laboratory. Do not be intimidated by the requirements of the project. If you are
 interested in the project, best to just talk to me about what is involved.
 This project will be done in collaboration with Dr Vasilis Dakos
 (https://www.vasilisdakos.info/) who is at the University of Montpellier and the CNRS
 (French National Centre for Scientific Research) in France
 Number of student places available: 1
 Delivery: Project can be completed through remote working arrangement if necessary.
 Expected outcomes: Scholars will learn about tipping points in ecological systems, and how
 to apply mathematical and computational techniques to explore how genetic variation
 affects tipping point behaviour.
 This is an extremely ‘hot’ and important topic in global change biology.
 Scholars will also have an opportunity to collaborate with world class researchers in Paris,
 France on ecosystem resilience.
 We are optimistic that with good progress, this work will result in an important peer-
 reviewed scientific publication, which is extremely important for career progress in science.
 Suitable for: Ideally, Scholars will have some background in mathematics and/or computing.
 However, there may be options for modifying the project according to your skills and
 interests, so if you are interested in the project, please talk to me about your interests and
 background.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        Dr Andrew Letten                                    Duration: 8 weeks
 Contact           Email: a.letten@uq.edu.au
 Details:
                   Goddard (08), Room 242
 The effect of nutrient availability on the competitive hierarchy in fly gut bacteria
 The flow of nutrients through ecological systems fluctuates through time and yet the impact
 this variability has on the maintenance of biodiversity is poorly understood. The animal gut
 is one system where a predictive understanding of community dynamics holds significant
 appeal and where the resident microbiota experience significant fluctuations in resources.
 Numerous studies have shown that diet is a strong predictor of gut microbiome
 composition, with a switch in food type shifting the community structure in just a few hours.
 Much less is known, however, about the effects of frequency and amplitude of food intake
 on the gut microbiome. This knowledge gap is especially striking given that ecological theory
 predicts that temporal variation in nutrient availability (e.g., feast-famine vs. continuous
 intake) should strongly impact gut microbiome stability.
 The test-case for this project is the impact of resource fluctuations on 5 core bacteria
 species comprising the fruit fly (Drosophila melanogaster) gut microbiota. The fruit fly has
 long been a model for genetics and evolution, but it has also recently emerged as an
 attractive model-system for gut microbiome research. This experimental project will use
 mixed and monoculture microbial growth assays (in vitro; no fly work!) to investigate: trade-
 offs in resource usage amongst the core fly gut bacteria: and the outcomes of competition
 under different nutrient delivery regimes.
 Number of student places available: 2
 Delivery: Onsite attendance is required
 Expected outcomes: Develop expertise in bacterial culture, competition assays, optical
 density measurements etc. Also potential for more emphasis on modelling or analysis
 depending on student interests.
 Suitable for: Students with some exposure to bacterial culture and wet lab techniques or
 eagerness to learn! R skills also helpful but not required.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        Prof Cynthia Riginos                                 Duration: 6-10 weeks
 Contact           Email: c.riginos@uq.edu.au
 Details:
 Using environmental DNA to measure the biodiversity in Moreton Bay habitats
 Quandamooka Sea Country (Moreton Bay) sits adjacent to Brisbane and is heavily impacted
 by urbanisation and climate change. At the same time, the Bay is a region of notable
 biodiversity with many distinct habitats including coral reefs. Student scholars will
 contribute to an ongoing project that is using environmental DNA to characterise biological
 diversity in the Bay by habitats, space, and time.
 Number of student places available: 2
 Delivery: The Scholars will be required on-site at St Lucia for the project.
 Expected outcomes: Scholars will learn basic molecular skills and to prepare metabarcoding
 libraries. Depending on interest, scholars may also learn to undertake bioinformatics and
 analyses of the resultant data. These data will eventually lead to peer reviewed publications
 and may support a UNESCO submission by the Quandamooka traditional owners for World
 Heritage listing. Scholars may also be asked to produce a report or oral presentation at the
 end of their project.
 Suitable for: This project is suitable for highly motivated students with demonstrated
 attention to detail and enthusiasm for marine biodiversity. A background in ecology and/or
 marine science would be most appropriate for this project.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process. (Please use email: c.riginos@uq.edu.au). The projects are only
 feasible if access to campus and laboratories is not restricted.

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School of Chemistry and Molecular Biosciences

 Supervisor        Prof Avril Robertson & Dr Kylie Agnew-Francis       Duration: 10 weeks
 Contact           Email: a.robertson3@uq.edu.au
 Details:
                   k.agnewfrancis@uq.edu.au
 Antifungals targeting Cryptococcus Neoformans
 Infections caused by yeasts (Candida and Crytpococcus) and moulds (Aspergillus) are an
 increasing problem in healthcare with a global mortality rate of around 1.4 million, similar to
 tuberculosis and exceeding breast cancer or malaria. One of the most alarming and
 immediate threats is from the recently identified superbug, Candida Auris. Invasive C. auris
 causes blood-stream and wound infections with mortality rate of > 30%. C. auris is
 commonly mis-identified and frequently resistant to all major classes of antifungal drug.
 We have developed novel molecules with activity against deadly pathogenic fungi. We now
 have a unique opportunity to further our discovery through fully elucidating the mode(s) of
 action and developing an understanding of the antifungal structure-activity and structure-
 toxicity relationships of the series.
 Given the paucity of current antifungal drugs, and the severity of mycotic infections, new
 treatments are desperately needed.
 Number of student places available: 1
 Delivery: On-site attendance is required at the St Lucia campus (entirely laboratory based)
 Expected outcomes: The applicant will learn solution and solid phase synthesis techniques,
 purification and characterisation methods. If synthesis is successfully completed the
 molecules will be tested for antifungal activity.
 Suitable for: This project is open to applications from UQ enrolled students only with a
 background and interest in drug discovery. Synthetic organic chemistry skills are required,
 the applicant must have completed CHEM2054 as a minimum.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        Prof Avril Robertson & Dr Kylie Agnew-Francis       Duration: 10 weeks
 Contact           Email: a.robertson3@uq.edu.au
 Details:
                   k.agnewfrancis@uq.edu.au
 Novel Anti-inflammatory compounds targeting the innate immune system
 Inflammasomes are part of the innate immune system responsible for processing and
 subsequent release of the potent pyrogenic cytokines, interleukin 1β and interleukin 18.
 Inhibiting inflammasomes (such as NLRP3, AIM2, NLRC4) using small molecules is an exciting
 strategy for future treatment of inflammatory diseases including asthma, type 2 diabetes
 and also disorders of the brain such as Parkinson’s and Alzheimer’s diseases. In the
 Robertson group, there is more than one compound series and innate immune target under
 investigation in this area.
 Number of student places available: 1
 Delivery: On-site attendance is required at the St Lucia campus (entirely laboratory based)
 Expected outcomes: The student will learn and develop synthetic, purification and analytical
 skills contributing to our series for future patent and/or publication.
 Suitable for: This project is open to applications from UQ enrolled students only with a
 background and interest in drug discovery/organic chemistry. Must have completed
 CHEM2054 as a minimum.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        A/Prof Elizabeth Krenske                            Duration: 6-10 weeks
 Contact           Email: e.krenske@uq.edu.au
 Details:
 Computer simulations of (bio)molecular reactivity
 Our laboratory uses computer simulations to study how molecules react. By performing
 quantum chemical modelling we are able to explore the factors that control chemical
 behaviour, visualising molecules in atomic-level detail. A range of project topics are
 available, e.g. studying the behaviour of catalysts that degrade plastics, or studying how
 drug candidates bind to biological molecules leading to desirable or undesirable effects.
 Number of student places available: 2
 Delivery: On-site attendance is required, unless prevented by COVID-19 restrictions. If
 necessary, the project can be converted into a remote working arrangement, but this may
 involve a reduction in hours and/or change of project scope.
 Expected outcomes: Scholars may gain skills in molecular modelling and in understanding
 reaction mechanisms. Scholars may learn the activities of the broader research group (e.g.
 by participating in group meetings and activities) and will be asked to produce a short
 written report at the end of their project.
 Suitable for: This project is open to applications from UQ enrolled students majoring in
 Chemistry who have taken (or are currently taking) CHEM3011. Current or previous
 enrolment in CHEM3001 and/or CHEM3020 is also advantageous.
 Other important details: Interested students must contact the supervisor (by email at
 e.krenske@uq.edu.au), prior to submitting an application. Evidence of supervisor support is
 required to be uploaded as part of the application process.

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Supervisor        Prof Bostjan Kobe                                   Duration: 6-10 weeks
 Contact           Email: b.kobe@uq.edu.au
 Details:
 Structural studies of proteins involved in infection and immunity
 The aim of this project is to use structural biology to understand the molecular basis of
 processes involved in infection and immunity. The work has implications for treating a range
 of infectious and inflammatory diseases and cancer, or for minimizing plant disease. We are
 focusing in particular on the proteins involved in cytoplasmic signalling by Toll-like
 receptors, bacterial pathogenesis, and effector-triggered immunity by plants. The main
 techniques will involve protein expression, purification, crystallization and structure
 determination, molecular interaction analyses and characterization of functional effects of
 site-directed mutants.
 Number of student places available: 2
 Delivery: Physical attendance at the lab is required
 Expected outcomes: Scholars will gain skills in various lab techniques mentioned above and
 have an opportunity to contribute to publications from their research. Students may also be
 asked to produce a report or oral presentation at the end of their project.
 Suitable for: Students with background in biochemistry, biophysics and other relevant areas
 is an advantage. We are looking for motivated students with interest in research in the areas
 the lab works in.
 Other important details: Interested students must contact the supervisor
 (b.kobe@uq.edu.au), prior to submitting an application. Evidence of supervisor support is
 required to be uploaded as part of the application process.

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Supervisor        A/Prof Shih-Chun (Lawrence) Lo                      Duration: 8 weeks
 Contact           Email: s.lo@uq.edu.au
 Details:
 Highly luminescent organic materials for Augmented Realities
 The project aims to develop highly luminescent organic chromophores that can be used for
 organic electronic devices such as organic light-emitting diodes (OLEDs for next-generation
 displays and lightings or augmented realities), and organic lasers. Compared to inorganic
 semiconductor counterparts, organic semiconductor materials offer many key advantages
 such as more light-weight, highly tunable, relatively cheaper and easier in materials
 synthesis and fabrication. The interests and demands on highly luminescent organic
 chromophores have been increasing in particular for bio-applications (such as bio-imaging,
 sensing) or organic electronics. It is challenging to generate organic chromophores with
 strongly luminescent in both solution and solid state, and simultaneously exhibit
 appropriate energy levels for charges injection in devices. The project will develop new
 organic semiconductor chromophores and study their properties for the potential in next-
 generation organic electronics including augmented realities or organic laser.
 Number of student places available: 2
 Delivery: Laboratory attendance is required. Alternative arrangement might be needed to
 adapt to COVID-19 lockdown, if any.
 Expected outcomes: Students are expected to learn how to design, synthesis, purify and
 characterise organic materials, as well as the working principles and usage in organic
 electronic devices. Students will also have opportunities to learn advanced photophysics
 and device physics through working closely with physics collaborators at QU’s School of
 Mathematics and Physics.
 Suitable for: Students have strong interest in organic material development and synthesis as
 well as learning how organic electronics work and play roles in our next-generation laser and
 augmented realities technologies.
 Other important details: Interested students must contact the supervisor (s.lo@uq.edu.au),
 prior to submitting an application. Evidence of supervisor support is required to be
 uploaded as part of the application process.

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Supervisor        Prof Jack Clegg                                     Duration: 6-10 weeks
 Contact           Email: j.clegg@uq.edu.au
 Details:
 New components for the synthesis of metal-organic frameworks
 Metal-Organic Frameworks are a class of polymeric material formed from organic and
 metallic components. This project explores new ways to form these materials following an
 innovative hierarchical self-assembly methodology.
 Number of student places available: 2
 Delivery: On-site attendance is required.
 Expected outcomes: You'll design and prepare a new organic compound, then investigate its
 interactions with a variety of metal ions. This project requires some synthetic laboratory
 work.
 Suitable for: Students who have completed CHEM2054 as a minimum.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process.

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Supervisor        Prof Bernie Carroll                                    Duration: 6 weeks
 Contact           Email: b.carroll@uq.edu.au
 Details:
 Mechanism of RNA interference (RNAi) and epigenetics in plants
 Gene silencing is a highly conserved process in plants and animals. It is of fundamental
 importance to gene regulation, virus protection, genome response to environment, and
 genome evolution. Remarkably, when silencing is triggered against a virus or an abundantly
 expressed gene in plants, it can spread throughout the organism. Application of exogenous
 RNA can also induce systemic virus resistance and gene silencing in plants. The aim of this
 project is to identify genetic mechanisms controlling systemic gene silencing induced by
 exogenous application of RNA in plants. The long term aim of the research is to use topical
 application of RNA to provide resistance against viruses and other plant pathogens, and to
 manipulate crop traits in “real-time” in the field to optimize adaptation to changing local
 climate conditions and harvest time for market opportunities.
 Number of student places available: 2
 Delivery: Applicants will be required on-site for most of the project.
 Expected outcomes: Applicants can expect to gain experience and knowledge in PCR-based
 genotyping of plants for mutations in genes involved in RNAi and epigenetics, crossing and
 grafting Arabidopsis plants, genetic mapping, screening for reporter gene expression, and/or
 collection and analysis of data. Students may also be asked to produce a report or oral
 presentation at the end of their project.
 Suitable for: This project is open to applications from students with a strong interest in
 molecular genetics, genetic and epigenetic mechanisms, year 3 undergraduate and
 postgraduate students.
 Other important details: Interested students must contact the supervisor/s, prior to
 submitting an application. Evidence of supervisor support is required to be uploaded as part
 of the application process. Students are also welcome to contact the supervisor if they are
 interested in a related project area.

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Supervisor        Prof Elizabeth Gillam                               Duration: 8 weeks
 Contact           Email: e.gillam@uq.edu.au
 Details:
 Engineering P450 enzymes for a sustainable source of plant hormones to improve food
 security across the world
 Strigolactones (SLs) are plant hormones that control many traits important for agriculture,
 such as shoot and root architecture, nutrient uptake and beneficial interactions with soil
 fungi that enhance plant viability. However they have also been exploited by parasitic
 weeds, for which they act as a germination signal. Parasitic weeds are widespread in arable
 lands of many developing countries and have devastating impacts on food production. The
 seeds of parasitic plants germinate when they detect SLs in the soil as this indicates the
 proximity of a host plant root which they can then invade. Application of synthetic SLs to
 infested soils would provide a way to clear arable land of parasitic weeds and greatly
 enhance food security in the third world. Biotechnological sources of natural or chemically
 modified SLs would also improve agricultural crop yield, especially from poor soils, and
 reduce manual labour costs in horticultural industries.
 The overall objective of this project is to develop microbial biofactories for SL production
 and to engineer ‘designer’ SLs that have specific functions by manipulating the cytochrome
 P450 enzymes catalysing SL biosynthesis. We will do so by analysing the evolution of
 naturally occurring SL-synthesising enzymes and leveraging ancestral sequence
 reconstruction to engineer robust novel 'designer' enzymes with specific desired activities.
 The vacation project would involve:
 (i) performing an ancestral sequence reconstruction on two P450 families involved in SL
 biosynthesis (this part could be done by working at home);
 (ii) expressing a number of extant and ancestral SL-producing P450 enzymes in E. coli for
 further characterisation subsequently (laboratory based experiments).
 Number of student places available: 1
 Delivery: Applicants will be required to be on-campus for the laboratory-based aspects of
 the project. However, in the event of an unexpected lockdown, at least part of the project
 can be done online.
 Expected outcomes: Students will acquire skills in molecular cloning, bacterial expression
 and characterisation of enzymes using specialised spectrophotometric methods, and high-
 performance liquid chromatography. They will also acquire skills in bioinformatics, especially
 analysing evolutionary relationships between proteins and in sequence curation, alignment
 and interpretation.
 Suitable for: This project would suit students with strong results in biochemistry, chemistry,
 plant biology or bioinformatics and an interest in enzymes and their evolution.
 Other important details: Please send Prof. Elizabeth Gillam your CV, academic record and a
 brief cover email explaining why you would like to do this project prior to submitting an
 application.
 Interested students must contact the supervisor/s, prior to submitting an application.
 Evidence of supervisor support is required to be uploaded as part of the application process.

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