ALWAYS ACTIVENo. 33 OCTOBER 2016 - AUTOPHAGY COMPLEMENTING DUOS READY FOR THE WINTER?
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ACTIVE
No. 33 OCTOBER 2016
ALWAYS
HL PROFESSIONAL SKINCARE
AUTOPHAGY
COMPLEMENTING
DUOS
READY FOR
THE WINTER?
AUTOPHAGY
Autophagy, the process of self-digestion by a cell in diabetes, neurodegenerative disorders as well as
through the action of enzymes originating within the infectious diseases because a fault in the process can
same cell. result in abnormal cell growth or cell death. In regards to
the dermis, age, UV and free radicals inhibit autophagy
The word autophagy is derived from Greek words
and accelerate cutaneous damage due to inadequate
“auto” meaning self and “phagy” meaning eating. It is
cellular processes. The suppression of autophagy
a normal physiological process in the body that deals
leads to a decrease in collagen synthesis, irregular cell
with destruction of cells and helps maintain normal
differentiation and delay of key differentiation markers in
functioning by protein degradation and turnover of the
skin keratinocytes.
destroyed cell organelles for new cell formation. In short
autophagy is similar to the cells' housekeeping process
as it clears away damaged organelles, insoluble proteins
and other unwanted cellular waste.
In skin, it is considered an important mechanism
being essential for detoxifying cells and guaranteeing
their correct functioning thus limiting the senescence,
aging or process of deterioration with age. Through an
optimal cell detoxification process the skin cells function
The 2016 Nobel Prize in Physiology or Medicine
properly, prevent their degeneration and lack of optimal
is the Japanese biologist Yoshinori Ohsumi was
functioning that eventually translates to premature
awarded the prize for having elucidated the
aging of the skin, loss of radiance and elasticity. Without
biological mechanism of autophagy.
a proper removal of the unnecessary and damaged
cellular constituents, the cell survival, longevity and His work showed the importance of autophagy
function are disrupted. dysfunctions in a number of pathologies, as well as
in the aging process.
Misregulation of autophagy can result in a variety of
pathological conditions, for example it plays a role
2 A l w a y s A c t i v e
COMPLEMENTING DUOS
NOURISHING KIT LIMITED
EDITION
!
MULTI VITAMIN - a unique treatment series
based on plant extracts that provide the skin with
moisture and nutrients to return its natural glow
and essential vitamins A, B, C, E, F, H complex
encapsulated to increase activity and maintain
them fresh.
The vitamins work synergistically to slow down
the skin's aging process and improve the firmness
and elasticity.
MULTI VITAMIN MULTI VITAMIN
SERUM RICH MOISTURIZING CREAM
Unique topical serum with encapsulated active
Moisturizing cream enriched with vitamins
vitamins A, C, E, F in a soothing concentrated
A, B, F and H, a potent complex that works
blend of plant extracts and vitamin H to help
+
synergistically to nourish the skin and to
prevent premature skin aging. The potent
improve firmness and elasticity. In addition,
cocktail of essential antioxidants moisturizes,
the cream contains encapsulated vitamin
nourishes, strengthens the
E, this helps preserve its ability to fight
epidermis, balances and
premature aging of the
soothes the complexion.
skin and prevent the
Daily application will ensure
appearance of fine lines
smooth, soft texture and a
and age signs.
youthful glow to the skin.
BENEFITS OF LAYERING
1. First apply MULTI VITAMIN SERUM, the concentrated serum will
allow active ingredients to penetrate the skin.
2. Follow with MULTI VITAMIN RICH MOISTURIZING CREAM to
increase moisture, improve firmness and fight premature aging of
the skin.
A l w a y s A c t i v e 3
TIPS FOR HEALTHY SKIN
THIS WINTER
Dehydrated skin is one of the most common skin
conditions especially during the cold winter months.
Factors such as cold weather, a decrease in humidity,
extended periods of time in-doors in heated areas affect
the skin and can lead to dry, uncomfortable skin.
The skin needs constant and long-lasting moisture in
order to function properly. Optimum levels of moisture
help in its appearance and give it a healthier, more
elastic, younger looking and radiant look. When the
moisture level in the skin is below optimal it will also • foods rich in vitamins B, whole-grain cereals,
show in its appearance as well, with more dull looking, whole rice, lentils, nuts, meat and milk products;
saggy texture; moreover it affects the skin’s natural essential to protect the skin and help skin renewal
barrier function which is essential to limit loss of moisture and collagen synthesis
and the penetration of pathogens. This epidermal • omega 3 rich foods will help preserve the skin’s
barrier, known as hydrolipidic layer, is composed of elasticity and prevent inflammation and irritation
sebaceous lipids, horny cells, cellular substances and 2. Avoid over heating the house and use a humidifier
MNFs (Natural Moisturizing Factors) and its key role to to add a significant amount of moisture to the air.
maintain the integrity of the barrier that defends the skin.
3. Update the skin care routine to one which is suitable
Common causes of dry skin include: for the cold winter months and will help maintain
• Climates with cold temperatures and low humidity skin’s moisture despite the harsh external factors.
• Very hot baths
4. Moisturizers are an important weapon in the
• Overuse of inadequate skincare products as well as
daily skincare routine all year round and the right
exposure to harsh chemicals
moisturizers will aid long-term control of dry skin
• Lack of water and lipids in the outermost layer of the
and promote prevention. Boosting the daily skincare
skin for it to function properly
routine with super moisturizers will increase moisture
• Intrinsic aging
and preserve the skin’s natural moisture level; these
• Genetics and certain types of skin diseases
include:
Consequences of dry skin:
• humectants that facilitate water retention such as
• Itchiness
glycerin, urea, lactic acid and hyaluronic acid
• Areas of thickened, rough skin
• occlusives to physically block trans-epidermal
• Painful cracks in the skin
water loss in the stratum corneum
• Red, inflamed, scaly skin
• ceramides and fatty acids to replenish and
• Round, scaly, itchy red patches on the skin
strengthen the skin barrier
Goals to helps preserve the skin’s moisture throughout
winter time: 5. Sun protection is just as important during the winter
1. A healthy balanced diet will help maintain a healthy, as it is during the summer months. The rules are the
balanced skin from inside out, and should include: same; it is recommended to apply daily a broad sun
• vegetables and fruit especially rich in antioxidants protector approximately 30 minutes before exposure
as well as vitamins A, C and E; will offer the much and reapply often during prolonged exposure to su.
needed antioxidant protection and help restore skin Make sure to apply to face, neck, ears and hands as
moisture well.
4 A l w a y s A c t i v e
PRODUCT SPOTLIGHT
ALPHA-BETA WITH RETINOL
PREPPING LOTION
DESCRIPTION: Hidden under the skin’s surface is a
healthier, smoother, younger looking skin. To reinforce
the efficiency of Alpha-Beta with Retinol products and
to ensure an effective exfoliaton use the Alpha-Beta
with Retinol Prepping Lotion. This lotion acts as an
enzymatic peeling and it is the first step in the Alpha-
Beta with Retinol treatment. It contains natural Alpha
& Beta Hydroxy Acids to enhance the cells’ natural
renewal process.
DIRECTIONS: Apply the lotion with the help of a
cotton ball and wait until it is fully absorbed then follow
with Alpha-Beta with Retinol Day Defense Cream or
Restoring Cream. It can be used daily to enhance the
natural balance of the skin.
RECOMMENDED: For all skin types
INGREDIENTS: Water (Aqua), Propylene Glycol,
Alcohol (Denat.), Vaccinium Myrtillus (Bilberry) Fruit
Extract, Salicylic Acid, Glycolic Acid, Sodium Lactate,
Saccharum Officinarum (Sugar Cane) Extract, Lactic
Acid, Acer Saccharum (Sugar Maple) Extract, Citrus
Aurantium Dulcis (Orange) Fruit Extract, Citrus Limon
(Lemon) Fruit Extract, Camellia Sinensis (Green Tea) Leaf
Extract, Glycerin, Retinol, 2-Bromo-2-Nitropropane-1,3-
Diol.
AVAILABLE IN: 125 ml / 4.2 fl oz
250 ml / 8.5 fl oz
REFERENCE #: 111024
111023
A l w a y s A c t i v e 5
Vitamin C, known as ascorbic acid, is a water-soluble C plays an important role in slowing the uncontrolled
antioxidant. As such it plays a vital role in neutralizing production of melanin and as such it is necessary to
free radicals in the water part of body tissue. The free reduce pigmentation spots that appear after excessive
radicals damage the skin, cause a loss of its flexibility, exposure to the sun. The exact mechanism of this
make it tough and rough and cause rapid aging and positive activity has yet to be analyzed, but researchers
even the formation of carcinogenic changes. Because assume that as an antioxidant, it delays the oxidation
it is water soluble, vitamin C is not stored in our body in stage in the production of melanin. In cases of severe
significant quantities and therefore we must make sure wounds, surgery, burns and in extreme temperatures,
to obtain it from food every day. as well as in states of stress and depression, our bodies
tend to use vitamin C more intensively, and therefore it is
Most animals produce ascorbic acid in their bodies.
important to top up its level. Also people who live close
Exceptions to this are the large mammals, among
to industrial zones, where large amounts of CO2 are
them man. Only for these mammals, ascorbic acid
emitted into the air, require large quantities of vitamin C,
is a vitamin. According to its definition, a vitamin is a
as inhaling CO2 destroys the Vitamin C. Smoking, birth
vital substance for the body, but that which the body
control, alcohol, excessive consumption of processed
is unable to produce itself in sufficient quantities, and
foods and over-exposure to the sun, all contribute to
therefore must be obtained from food.
the depletion of vitamin reserves in our bodies, thereby
Ascorbic acid plays an important role in the biochemical increasing the risk of carcinogenic changes in the skin.
process of synthesis of collagen, the most common
Clinical studies have proven that the topical application
protein in the human body. This fibrous protein
of the vitamin can result in “renewed interwining” of
constitutes the most important component of the skin
the collagen fibers in adult skin. Additional studies
and plays a key role in the building and maintenance of
show that vitamin C is absorbed better when applied
the skin.
topically rather than taken orally. Moreover, these
It is also responsible for assimilating the collagen in the studies demonstrated that when applied topically, the
dermis – the layer of skin found below the epidermis. vitamin is absorbed 20-40 times deeper than when it is
When there is a lack of vitamin C, collagen cannot form absorbed via the digestive system. The main problem
its typical fibrous structure and as a result the skin posed by vitamin C to the cosmetic industry is that it is
loses elasticity and vitality. Vitamin C is also involved an unstable substance, sensitive to water, air, heat and
in the synthesis of other important components in even light. As a result, it is very difficult to store without
connective tissues, among them elastin, fibronectin some of its effectiveness being lost.
and proteoglycans. In addition, it appears that vitamin
6 A l w a y s A c t i v e
MULTI VITAMIN
NEW
The MULTI VITAMIN line is based on plant extracts and essential
encapsulated vitamins A, B, C, E, F, H that provide the skin with
moisture and nutrients to return its natural glow.
Always Active
e-mail: info@hl-labs.com | www.hl-labs.com | HL - PROFESSIONAL SKINCARE
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