Diarrhoea and Constipation

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Diarrhoea and Constipation Edition 4 – June 2015

                                                                                                  Improving life for
                                                                                                  people affected
Crohn's and Colitis UK Information Sheet                                                          by inflammatory
                                                                                                  bowel diseases

Diarrhoea and Constipation
Introduction
                                                                  When we eat, food passes down the
Diarrhoea is one of the main symptoms of
                                                                  oesophagus (gullet) and then into the
Inflammatory Bowel Disease (IBD), which
                                                                  stomach, where it is broken down by
includes Crohn’s Disease and Ulcerative
                                                                  gastric (stomach) juices to a porridge-like
Colitis (UC). Microscopic Colitis, another
                                                                  consistency.
form of IBD, can also cause diarrhoea.

IBD treatment aims to control the
symptoms and keep you in remission. Yet
some people with IBD continue to have
diarrhoea. This leaflet looks at why this
might happen and includes some
suggestions about ways to help reduce
and manage diarrhoea.

Some people with IBD may experience
constipation. This leaflet looks at the
causes of constipation, and how you may
be able to alleviate it.

What is diarrhoea?
Diarrhoea is generally defined as passing
loose watery stools (faeces, poo) at least
3 times a day. There is often a feeling of
‘urgency’, a need to rush to the toilet.
Sometimes the diarrhoea can be
explosive. It may also lead to bowel                              The partly digested food then moves into
incontinence with a leakage of faeces.                            the small intestine where most of the
                                                                  nutrients are absorbed.
If the diarrhoea lasts less than four weeks,
it is usually referred to as ‘acute                               The waste, now a watery slurry, passes
diarrhoea’. If it lasts for four weeks or                         into the colon. It is here that most of the
more, it is generally thought of as ‘chronic’                     water is normally absorbed so the waste
(ongoing) diarrhoea.                                              can form solid stools (faeces). These
                                                                  collect in the last part of the colon and the
Diarrhoea happens when the colon (large                           rectum and are passed out of the body in
intestine or large bowel) cannot absorb all                       a bowel movement.
the fluid produced during the digestive
process.                                                          Diarrhoea is a common symptom of IBD
                                                                  affecting the large bowel. During a flare-
As shown in the diagram, the                                      up, the cells in the lining of the colon
gastrointestinal (digestive) tract is a long                      become inflamed and do not work
tube that starts at the mouth and ends at                         properly. The colon cannot absorb all the
the anus.                                                         fluid and the stools remain loose and
                                                                  watery, or even entirely liquid – and this is
                                                                  experienced as diarrhoea.

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Diarrhoea and Constipation Edition 4 – June 2015

The looser faeces can also move more                  However, if part of the ileum is lost,
rapidly through the colon, causing more               much higher levels of bile salts can
frequent bowel movements.                             drain into the colon. This can irritate
                                                      the colon causing watery diarrhoea.
What causes diarrhoea?                                Inflammation of the end of the ileum
If you have IBD, your diarrhoea may be                can also lead to bile salt diarrhoea as
due to a flare-up of your disease -                   well as to poor fat absorption (see
although there are also some other factors            below).
which may be causing the diarrhoea or
making it worse.                                    Malabsorption of fats - If you have
                                                      Crohn’s in the ileum (the lower part of
 Side effects of drugs for IBD - One of              the small intestine) you may have
   the rare side effects of 5-ASAs such as            difficulty absorbing fats. This can lead
   mesalazine and sulphasalazine, is                  to urgency and to pale and bad
   watery diarrhoea. You may be able to               smelling, poorly formed faeces that are
   reduce this side effect by taking the              difficult to flush away.
   tablets with or after food. Some of the
   immunosuppressants, such as                      Iron Supplements - You may be
   azathioprine and methotrexate, can                 prescribed iron supplements for
   also cause diarrhoea especially during             anaemia caused by your IBD. A
   the early weeks of treatment. Talk to              change in bowel habit is a common
   your doctor or IBD team about ways to              side effect of iron supplements and
   manage this, or see our Drug                       while some people get constipation,
   Treatment leaflets, Azathioprine and               others get diarrhoea.
   Methotrexate, for further information.
                                                    Irritable Bowel Syndrome (IBS) - IBS
 Side effects of other drugs - You may               is sometimes confused with
   also find it helpful to check whether              Inflammatory Bowel Disease, but is a
   diarrhoea is a side effect of any other            separate and different condition. Some
   medications you are taking. Antibiotics            of the typical symptoms of IBS, such as
   and acid-lowering treatments, such as              diarrhoea and colicky pain, can be very
   omeprazole and lansoprazole, can also              similar to those of IBD, but IBS does
   cause diarrhoea.                                   not cause inflammation or bleeding.
                                                      However, it is possible that some
 Colectomy and ileo-rectal                           people with Ulcerative Colitis or Crohn’s
   anastomosis - In this operation the                Disease may have irritable bowel
   colon is removed and the ileum (the                symptoms as well as IBD – probably
   lower part of the small intestine) is              because the inflammation has
   joined directly to the rectum. After this          temporarily affected the nerve endings
   procedure, your faeces will tend to be             in the bowel. So they may, for
   much more liquid because you no                    example, continue to experience
   longer have a colon to absorb the                  diarrhoea following an IBD flare-up,
   water.                                             even when the inflammation has died
                                                      down.
 Small bowel surgery for Crohn’s
   Disease - If you have had the end of
   the ileum (the lower part of the small
   intestine) removed, you may have bile
   salt diarrhoea. Bile salts are produced
   in the liver and are usually reabsorbed
   in the ileum, so that only very small
   amounts enter the colon.

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Diarrhoea and Constipation Edition 4 – June 2015

 Diet and food sensitivities - Some                Antidiarrhoeal drugs - Antidiarrhoeals
    people are sensitive to particular foods,         work by slowing down the contractions
    such as milk and wheat. Too much                  (muscle movements) of the gut, so that
    fibre, spicy food, chocolate, caffeine (in        the food takes longer to pass through
    coffee, tea and cola drinks), alcohol,            your system. This allows more time for
    fructose (a sugar in fruit) and artificial        the water to be reabsorbed and for the
    sweeteners (sorbitol) can all have a              stools to become firmer and less
    laxative effect, stimulating and                  urgent, but should generally
    loosening the bowels. Intolerance to              be avoided if your large bowel is
    lactose, a natural sugar found in milk,           affected by your IBD (see below).
    can cause diarrhoea. If you are                   Loperamide (Imodium, Arret) is a
    concerned about diet and food                     commonly used and effective
    sensitivities, ask your IBD team to refer         antidiarrhoeal drug. It is long-acting
    you to a dietitian.                               and usually only needs to be taken
                                                      once or twice a day, although it can be
   Infections - In people without IBD,               taken more often if needed. Other
    diarrhoea can often be a sign of:                 antidiarrhoeals such as diphenoxylate
                                                      (Lomotil) and codeine may need to be
       gastroenteritis – an infection of the         taken three or four times a day.
        large bowel, commonly caused by               The patient information leaflets that
        a virus or bacteria or,                       come with all antidiarrhoeals advise
                                                      against taking them if you have IBD,
       Clostridium difficile (also known as
                                                      particularly if you are having a flare-up
        C. diff) – a type of bacterial
                                                      of UC. This is because there are risks
        infection that can affect the
                                                      of side effects, including toxic
        digestive system.
                                                      megacolon (when digestive gases get
                                                      trapped in the colon, making it swell
    These infections can also affect people
                                                      up) associated with taking these drugs.
    with IBD and your doctor or IBD team
                                                      So, whichever condition you have, if
    may carry out tests to make sure your
                                                      you are having an acute or severe
    diarrhoea is not at least partly due to
                                                      flare-up, do not take any antidiarrhoeal
    such infections.
                                                      medicines without first checking with
                                                      your doctor or IBD team.
What treatment can I take?
 Drugs used to treat active IBD – A
  range of drugs are used to treat IBD
                                                    Antispasmodic drugs - These work
                                                      by relaxing the intestinal muscles to
  and then to help maintain remission
                                                      slow down bowel movements in a way
  once it is under control. If you are on
                                                      that not only helps to relieve diarrhoea,
  such medication, you should find your
                                                      but also the cramping pain often
  diarrhoea lessens as the drugs
                                                      accompanying diarrhoea. Brands
  prescribed for your IBD take effect.
                                                      include Buscopan and Colofac. They
  Some drugs, such as 5-ASAs and
                                                      are usually safe to take, but check with
  steroids, tend to act quickly while
                                                      your doctor first.
  others, such as azathioprine and
  methotrexate, take much longer to
  work. As mentioned earlier, some                  Bile salt drugs - These include
  people may get diarrhoea as a side                  colestyramine (Questran) and
  effect of these medications. If you do              colestipol (Colestid) which come in
  continue to have a flare-up or to                   powder or granule form, and a newer
  experience serious diarrhoea, you may               drug, colesevelam, which comes as
  need to change your medication. Talk                tablets.
  to your specialist about this.

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Diarrhoea and Constipation Edition 4 – June 2015

   These bile salt drugs absorb the                Eating
   overflow bile salts, preventing them             Eat small, frequent meals.
   reaching the colon and causing                   Keep a food diary and note down any
   diarrhoea. They can affect the                     foods that seem to upset you, so you
   absorption of other drugs that you may             can avoid them. However, it is not
   be taking for your IBD. If you are                 advisable to cut out too many food
   taking other drugs, it is worth checking           groups, and if you find you are
   with your IBD team whether they will               avoiding many different types of food,
   be affected by the bile salt drugs, and            it may be helpful to consult a dietitian
   if so, how you can manage taking both.             to help you balance your diet.
   There is also an alternative ‘lite’                Some sensitivities might be only
   version of colestyramine available, but            temporary and you may be able to re-
   this can cause these side effects too.             introduce that food at a later date. If
   If you are taking colestyramine and                your diarrhoea is worse after you have
   have experienced side effects, it may              eaten foods containing gluten (a
   be worth asking if you can try the lite            protein found in wheat, barley and rye)
   version as in some people this causes              it may be due to an intolerance to
   fewer side effects.                                gluten. But it could also be a sign of
                                                      coeliac disease. This is a condition in
 Bulking agents - Bulking agents or                  which the immune system mistakes
   ‘bulk formers’ are made from a type of             substances found inside gluten as a
   plant fibre (usually ispaghula or                  threat to the body and attacks them.
   sterculia). Popular brands include                 This damages the surface of the small
   Fybogel and Isogel. These come as                  bowel (intestines) disrupting the body's
   granules which, when taken with plenty             ability to absorb nutrients from food.
   of water, swell up inside the bowel,               There are tests to diagnose coeliac
   thickening liquid stools or softening              disease. If you are concerned that
   hard stools and so providing the bulk              foods containing gluten are affecting
   needed for the bowel to work more                  you, speak to your IBD team to see if
   normally. Bulking agents can be                    they can refer you to a dietitian.
   useful for both diarrhoea and                    For many people, foods rich in fibre
   constipation. They are generally safe              tend to make diarrhoea worse. Don’t
   for people with IBD, although they may             give up all fruit and vegetables, but try
   cause bloating and wind, but should be             cutting down on high fibre foods such
   avoided if you have a stricture                    as bran cereal, pulses (peas and
   (narrowing) of the bowel, as                       beans) and the type of fruits or
   sometimes happens with Crohn’s                     vegetables usually eaten with the
   Disease.                                           skins, pips and seeds. Onions can be
                                                      particularly troublesome.
You can find further information on all             Avoid hot or spicy foods, if they don’t
these types of drugs in our booklet Drugs             agree with you.
used in IBD and our individual drug                 If milk makes your diarrhoea worse, try
treatment information sheets.                         using a lactose free milk and avoiding
                                                      foods made with milk such as custards
Can changing what I eat and drink                     and sauces. Some medicines also
help?                                                 contain lactose, but do not stop taking
You may find that you have diarrhoea                  any prescribed medication without
whatever you eat or drink, but some                   checking with your IBD team.
people find altering their diet helps to            Chicken and rice soup is a traditional
reduce diarrhoea. Everyone is different               remedy for diarrhoea, which some
and what works for others may not work                people have found useful.
for you. However, the following
suggestions may be of some assistance.

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Diarrhoea and Constipation Edition 4 – June 2015

    Carrot soup is also said to be soothing           Use moist toilet paper, damp cotton
    for the gut, and is rich in beta-carotene          wool, or moist toilet wipes. Many baby
    which may promote healing.                         wipes contain alcohol and are best
   The BRAT diet, (bananas, rice,                     avoided, although there are now some
    applesauce and toast – or tea) is also             ‘alcohol-free’ brands.
    traditionally recommended as a way of
    reducing acute diarrhoea. But this                Whenever possible wash around the
    does not contain enough nutrients to               anus after a bowel movement. A bidet
    be a healthy long term option.                     is ideal, but you could also use a
                                                       shower attachment while sitting with
Other ‘special diets’ may also reduce                  your bottom over the edge of the bath.
diarrhoea. However, in order to make                   Or use a soft disposable cloth with
sure that you are still getting a balanced             warm water. Avoid flannels and
and nutritious intake, these are best used             sponges as they can be rough and are
only with the advice of a qualified dietitian.         difficult to keep clean.

Drinking                                              Use non-scented soap or a special
 Many people are sensitive to caffeine,               washing solution. There are products
    so try opting for decaffeinated coffee,            specifically developed for people with
    tea, and cola drinks.                              bowel problems. Ask your nurse about
 Reduce your consumption of alcohol,                  these or contact the Bladder and
    particularly beer and lager, as this is            Bowel Foundation for more
    known to have a laxative effect.                   information. Avoid using antiseptics or
 Drinks made with artificial sweeteners               disinfectants in washing water, as
    can also cause diarrhoea.                          these can sting.

For more information on healthy eating                Dry the area very gently, patting with
with IBD see our booklet, Food and IBD.                soft toilet paper or soft towel. Do not
                                                       rub. If you are very sore you could use
What should I do about the other                       a hairdryer on a low setting.
symptoms which may come with
diarrhoea?                                            Use a barrier cream or ointment a little
If you have diarrhoea, you will lose more              at a time and rub it in gently. Large
water than usual with your stools. It is               amounts stop the skin from breathing
therefore especially important if you have             and can make the area sweaty and
IBD that you drink plenty of fluids. You               uncomfortable. Make sure the old
may also need to replace the salts and                 layer of cream is washed off before
sugars lost with the diarrhoea. One way                applying more. Choose a simple
to do this is to drink a commercial                    product such as zinc and castor oil. It
rehydration solution such as Dioralyte,                is better to avoid creams containing
Electrolade or Rehydrit.                               lanolin, as some people are allergic to
                                                       this. Other products you could try
For more serious dehydration your doctor               include Sudocrem, Cavilon, and
may recommend drinking an Oral                         Metanium.
Rehydration Solution (ORS) with a higher
sodium (salt) level. For more details on              Some people have found alternative
this and how to avoid and manage                       products helpful, including aloe vera
dehydration, see our information sheet,                gel, Kamillosan Baby Cream and
Dehydration.                                           Germoline.

How can I treat sore skin?                            Try to allow the air to get to the anal
Frequent diarrhoea and wiping can irritate             area for at least part of every day.
the skin around the anus, making it sore.
The following tips may help.

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Diarrhoea and Constipation Edition 4 – June 2015

   Try not to scratch the anal area, as this             occur in Crohn’s Disease (see How
    will make things worse. If you find you               can I treat constipation?)
    are scratching in your sleep, you could
    wear cotton gloves in bed (available                 Not enough fluids - If you are not
    from your chemist).                                   drinking enough, this can lead to
                                                          constipation as the stools become
   If you use a pad for incontinence,                    hard, dry and difficult to pass.
    make sure that the pad has a soft
    surface and that no plastic comes into               Drugs - As mentioned before,
    contact with your skin.                               constipation can be a side effect of
                                                          drugs, for example, anti-diarrhoeals
   Wear cotton underwear to allow the                    or codeine, which is found in some
    skin to breathe. Avoid tight jeans and                pain killers.
    other clothes that might rub the area.
    If you wear tights, think about changing             Damage to the anal muscles - A
    to stockings or crotchless tights.                    common cause of constipation in
                                                          women following vaginal childbirth
If you continue to feel sore, or if your skin             or pelvic surgery. A special test
is broken, talk to your doctor, nurse, or                 may be used to diagnose this.
IBD team. They may be able to prescribe
more effective medications. If the                 How can I treat constipation?
soreness persists you may have a fungal            You may find that drinking plenty of fluids
infection (such as thrush), which will             might help form softer stools which are
require different treatment.                       easier to pass. It may also help to
                                                   increase the amount of fibre in your diet,
What is constipation?                              although this might not work for all people,
Constipation can be defined as passing             for example, those with strictures. Some
stools fewer than 3 times per week,                people may find that bulking agents, such
needing to strain, or passing hard stools          as Fybogel or Isogel, can soften hard
which are unusually large or small. You            stools, but also may not be suitable if you
may find that a stool passing through an           have a stricture. If you can, increase the
area of inflammation in the colon can be           amount of exercise you do to help with
particularly painful.                              constipation and to speed the passage of
                                                   stools through your colon.
What causes constipation?
   Proctitis - You may be more likely             Laxatives can help to relieve constipation.
     to have constipation if you have              Osmotic laxatives, such as Movicol, are
     proctitis (inflammation of the                usually considered the best type of
     rectum).                                      laxative for people with IBD. These
                                                   increase the amount of water in the large
       IBS - Some people with IBD                 bowel so that stools can be passed more
        experience IBS symptoms, which             easily. However, laxatives can also cause
        can be constipation and/or                 wind and stomach cramps, especially at
        diarrhoea.                                 the start of treatment.

       Low fibre diet - Fibre helps stools        If you are worried about constipation and
        pass through the gut, so if you have       how to treat it, speak to your IBD team or
        reduced your intake of fibre, you          doctor.
        may find that you become
        constipated. Although excess fibre
        should be avoided if you have a
        stricture of your intestine, as can

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Diarrhoea and Constipation Edition 4 – June 2015

What other symptoms may come with                  Help and support from Crohn's and
constipation?                                      Colitis UK
Some people with constipation may                  All our information sheets and booklets
develop associated conditions such as              are available to download from our
haemorrhoids (also known as ‘piles’).              website: www.crohnsandcolitis.org.uk. If
Haemorrhoids are swellings that contain            you would like a printed copy, please
enlarged blood vessels that are found              contact our information line – details
inside or around the rectum and anus.              below.
Symptoms can include:
                                                   Crohn’s and Colitis UK Information
      bleeding after passing a stool              Line: 0845 130 2233: Open Monday to
      itchiness around the anus                   Friday, 9am to 5pm, excluding English
      a lump hanging down outside of the          bank holidays. An answer phone and
       anus, which may need to be                  call back service operates outside these
       pushed back in after passing a              hours. You can also contact the service
       stool.                                      by email info@crohnsandcolitis.org.uk or
                                                   letter (addressed to our St Albans office).
Initial treatments for haemorrhoids, if            Trained Information Officers provide
caused by constipation, are drinking               callers with clear and balanced
plenty of fluids, and increasing the fibre in      information on a wide range of issues
your diet. Although these may not be               relating to IBD.
suitable for everyone, particularly those
with strictures (see earlier How can I treat       Crohn’s and Colitis Support: 0845 130
constipation?) If these steps don’t work,          3344: Open Monday to Friday, 1 pm to
you may need to be referred to a                   3.30 pm and 6.30 pm to 9 pm, excluding
specialist for further treatment. If you are       English bank holidays. This is a
concerned that you may have                        confidential, supportive listening service,
haemorrhoids, speak to your IBD team               which is provided by trained volunteers
about it.                                          and available to anyone affected by IBD.
                                                   These volunteers are skilled in providing
Impact of having diarrhoea and                     emotional support to anyone who needs a
constipation on everyday life                      safe place to talk about living with IBD.
Many people with IBD can feel
embarrassed and upset about having                 Other support from Crohn’s and Colitis
diarrhoea and constipation. But if your            UK
symptoms are making you feel this way,             Crohn’s and Colitis UK Forum
you might find that talking about it helps.        This closed-group community on
You may wish to talk to a professional             Facebook is for everyone affected by IBD.
counsellor (see our information sheet              You can share your experiences and
Counselling and IBD). Or you may want              receive support from others at:
to speak to someone who understands                www.facebook.com/groups/CCUKforum
what it’s like to have IBD. Our confidential
listening service, Crohn’s and Colitis             Other Organisations
Support, is run by volunteers who have             Disability Rights UK
experience of IBD and are trained in               12 City Forum, 250 City Road, London,
giving emotional support (see Help and             EC1V 8AF
Support from Crohn’s and Colitis UK).              Website: www.disabilityrightsuk.org
                                                   From this organisation, you can purchase
You might also find it reassuring to speak         RADAR keys which allow access to
to other people with IBD and share                 specially adapted toilets.
experiences through the Crohn’s and
Colitis UK Facebook Forum.
See Other Support from Crohn’s and
Colitis UK for more details on the Forum.

                                                                                                 7
Diarrhoea and Constipation Edition 4 – June 2015

Irritable Bowel Syndrome Network (The
IBS Network)
Unit 1.12 SOAR Works, 14 Knutton Road,
Sheffield, S5 9NU
 0114 272 3253
Email: info@theibsnetwork.org
Website: www.theibsnetwork.org
The IBS Network is an independent, self
help organisation for people with Irritable
Bowel Syndrome. The helpline is staffed
by specialist IBS nurses.

 Crohn’s and Colitis UK 2015
Diarrhoea and Constipation – Edition 4
Last review: June 2015
Next planned review: 2017

Crohn's and Colitis UK publications are
research based and produced in consultation
with patients, medical advisers and other
health or associated professionals. They are
prepared as general information on a subject
and are not intended to replace specific
advice from your own doctor or any other
professional. Crohn's and Colitis UK does not
endorse or recommend any products
mentioned.

Crohn's and Colitis UK is an accredited
member of the Information Standard scheme
for Health and Social care information
producers.

We hope that you have found this leaflet
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the Publications Team at
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You can also write to us at Crohn's and Colitis
UK, 4 Beaumont House, Sutton Road, St
Albans, Herts. AL1 5HH or contact us through
the Information Line: 0845 130 2233.

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