Lower back pain: Global burden of disease and community-based care

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Lower back pain: Global burden of disease and community-based care
Lower back pain: Global burden
of disease and community-based
                           care
       Associate Professor Fiona Blyth MBBS (Hons)
                                      FAFPHM, PhD
      Discipline of Pain Medicine & Sydney School of
                                        Public Health
                                 University of Sydney
Overview of talk

Overview of GBD 2010 background and
 methods
Results for the burden of disease from low
 back pain globally and in Australia
Other Australian data on the population
 impact of back pain
GBD 2010 O
         Overallll Ai
                   Aims

To produce new
           new, robust
                 robust, and reliable
 estimates of burden for all major diseases,
 injuries and risks that are widely
 injuries,
 disseminated, understood, and easily used
 by policymakers, researchers, funders,
                                 f
 and practitioners.
      p
Why now?

Changing global demography
Changing global economy
Changing patterns of disease and
 di bilit
 disability
   eed for
Need    o a comprehensive
             co p e e s e a  andd syste
                                  systematic
                                        at c
 revision of global burden of disease
 estimates
GBD 1990 and onwards

 GBD 1990 began in 1991, first estimates in the
  World Development Report in 1993, final
  estimates published in 1996
                         1996.
 Collaboration of Harvard University, World Bank
  and World Health Organization.
                    Organization
 107 Diseases and Injuries, 10 Risk Factors,
  F
  Forecasts
         t to
            t 2020
 2000-
  2000-2004 WHO produced updates; ongoing
  methodological
     th d l i l enhancements
                  h       t
 GBD 2010 underway since 2008 (>175 diseases
  and
    d iinjuries,
         j i     20 risk
                     i k ffactors)
                             t )
GBD 2010
globalburden.org

Key collaborators:
Johns Hopkins University
Harvard University
University of Queensland
Institute for Health Metrics and Evaluation
  at the University of Washington
World Health Organization
Global Burden of Disease Organizational Structure
                                                                                                                            More than 480
                                                                                                                            experts globally
                                                                        Core Team

    External Advisory
         Board
                                                                                                                            participated in
                                                                                                                            GBD 2010

                  Tools and Curricula
                  Development Sub-
                         Team
                                                                                                                                                                Mortality
                                                                                      Cause of Death                               Disability Weights
                                                                                                        Comparative Risk                                       Estimation
                                                                                        Sub-Team                                       Sub-Team
                                                                                                           Sub-Team                                            Sub-Team
                                                                                      Alan Lopez and                               Josh Salomon and
                                                                                                          Majid Ezzati                                         Ken Hill and
                                                                                       Chris Murray                                  Colin Mathers
                                                                                                                                                              Kenji Shibuya

    Cluster A:                            Cluster B:                          Cluster C:                     Cluster D:                               Cluster E:
CVD, COPD, Cancer                       Child/Maternal               Injuries and Mental Health        Communicable Diseases                   Noncommunicable Diseases
    Majid Ezzati                           Bob Black                          Theo Vos                       Neff Walker                           Catherine Michaud
 Harvard University                 Johns Hopkins University           University of Queensland        Johns Hopkins University                    Harvard University

Expert Groups:                          Expert Groups:                Expert Groups:                    Expert Groups:                          Expert Groups:
Air Pollution (Risk)                    ARI Meningitis Sepsis         Alcohol (Risk)                    Hepatitis                               Anemia
Cancers                                 Child Nutrition (Risk)        Childhood Sexual Abuse (Risk)     HIV/AIDS                                Dental Health
CVD and Related Risks                   Congenital and Neonatal       Mental Disorders                  Other Infectious Diseases               Diabetes
Global Climate Change                   Enteric Infectious Disease    Musculoskeletal                   Other Parasitic and Vector Diseases     Digestive Disease
Respiratory Disease                     Maternal Conditions           Neurological Conditions           STDs                                    Endocrine Disorders
Tobacco (Risk)                          Malaria                       Occupational Risks (Risk)         Tuberculosis                            Genitourinary
                                        Other Childhood Diseases      S i id
                                                                      Suicide                                                                   Skin Diseases
                                                                      Unintentional Injuries                                                    Traffic Injuries
                                                                      War and Civil Conflict                                                    Vision and Hearing
Musculoskeletal conditions in GBD:
evolution over time

  •   Osteoarthritis (GBD 1990, 2000, 2010)
  •   Rheumatoid
        eu ato d a arthritis
                      t t s (G
                             (GBD 1990,
                                   990, 2000,2010)
                                         000, 0 0)
  •   Low Back pain ( LBP in GBD 2000, 2010)
  •   Neck Pain (GBD 2010)
  •   Gout (GBD 2010)
  •   Other MSK (GBD 2010)
Low Back Pain: the old GBD Model (GBD2000)

  LBP resulting in limitations on usual activities
                                          activities,
   Duration=4 days, no mortality
  Acute ((
Low back pain: the new GBD model

Based on extensive systematic review of the
 literature

Had to be consistent w natural history of LBP

Major constraints on how health states could be
 described
New definition

Case d
C     definition:
        fi iti    A
                  Activity-limiting
                    ti it li iti lowl  b
                                       backk pain
                                               i ((+/-pain
                                                    / i referred
                                                           f   d
to one or both legs) that lasts for at least one day.

Low back=area
Lo   back area on the posterior aspect of the bod
                                              body from the lower
                                                            lo er margin
of the 12th ribs to the lower gluteal folds

Acute/subacute < 3mths; Chronic 3 mths or more
How would you describe these low back
 pain health states so that they
 p                             y could be
 understood by ‘lay people’ in different
 communities and countries around the
 world?

How  would you do this for
                         f all the different
                                      ff
 diseases in GBD 2010?
Building a lay description from the Health State
Checklist

The first set of questions asks about capacity along several dimensions
  of functioning. Indicate by checking either ‘yes’ or ‘no’ whether a
  person would be able to perform the following functions.

Rising:
      g Rise from lying
                    y g position
                         p       on the ground
                                        g      (Yes/No);
                                               (      ); Rise from
   sitting position on the ground (Yes/No)
Building a lay description from the Health State
Checklist
The second
Th        d set off questions
                         i    asks
                                k about
                                   b    specific
                                             ifi symptoms
                                                        t   or
   problems. Indicate by checking either ‘yes’ or ‘no’ whether a person
   would experience the symptom or problem, and indicate average
   duration and/or frequency where relevant

Feeling worried or anxious (Yes/No; # days per week;# hours per
  day)
Quite a process!

                   Final versions had to be concise

                   Modified after feedback from
                   GBD central team which had
                   oversight of all disease groups

                   Major restrictions on both
                   l
                   length
                       th and
                            d content
                                  t t

                   Why? GBD is a RANKING exercise
The final lay descriptions
              descriptions...
 ACUTE BACK PAIN WITH LEG PAIN
  - “person with severe back and leg pain”
   This person has severe back and leg pain, which causes difficulty
   dressing sitting
   dressing, sitting, standing,
                      standing walking,
                                walking and lifting things
                                                    things. The person sleeps
   poorly and feels worried.

 CHRONIC LOW BACK PAIN WITH LEG PAIN
  - “person with constant back and leg pain”
   This person has constant back and leg pain, which causes difficulty
   dressing sitting
   dressing,  sitting, standing,
                       standing walking,
                                 walking and lifting things
                                                     things. The person sleeps
   poorly, is worried, and has lost some enjoyment in life.
Prior GBD estimates used disability weights based on valuations
f
from  h lth professionals
      health   f   i   l only
                           l (?h
                              (?how accurate)
                                            t )

Last GBD round, musculoskeletal conditions assigned low disability
weights→low ranking

This time: community surveys as well as health professional surveys
in different countries – asking a broader range of people to assess
disability
Overview of talk

Overview of GBD 2010 background and
 methods
Results for the burden of disease from low
 back pain globally and in Australia
Other Australian data on the population
 impact of back pain
‘Democratization
 Democratization of data’
                    data

International launch of results in triple
 issue of The Lancet in London (13(
 December 2012)
Open access data visualisation tools
 rapidly made available on Institute of
 Health Metrics Evaluation website:
http://www.healthmetricsandevaluation.org
 /gbd/visualizations/country
htt //
http://www.healthmetricsandevaluation.org/gbd/visualizations/country
           h lth t i      d   l ti       / bd/ i   li ti    /    t
http://www.healthmetricsandevaluation.org/gbd/visualizations/gbd-arrow-
htt  //    h lth t i      d   l ti       / bd/ i   li ti    / bd
diagram
http://www.healthmetricsandevaluation.org/gbd/visualizations/gbd-cause-
htt  //    h lth t i      d   l ti       / bd/ i   li ti    / bd
patterns
Musculoskeletal conditions

Widespread recognition of the huge disability
 burden globally and within Australia related to
 MSK conditions (NB low back pain and neck
 pain)
Surprisingly low disability weights for
 osteoarthritis
Significant gaps in basic data from many
 countries
Lack of consistent data to be addressed in the
 future (eg,
        (eg severity and length of episodes of
 LBP or neck pain)
Overview of talk

Overview of GBD 2010 background and
 methods
Results for the burden of disease from low
 back pain globally and in Australia
Other Australian data on the population
 impact of back pain
Australia’s Health 2012 Report (Australian Institute of
Health and Welfare): People with living with disability
(minimum 6 months duration, restricting everyday activity)
Australia’s Health 2012 Report (Australian Institute of
Health and Welfare): Health service use for MSK conditions

                            GP management: medications
                                               medications,
                            imaging,referrals, advice about
                            self-management

                            ?other primary care

                            ? Risk assessment/stratification
Key findings

Working age people with long-term back
 problems were more than two and a half
 p
 times more likely not to be in the labour
 force
 With three or more additional conditions,
 this goes up substantially – more than nine
                 y not to be in the labour
 times more likely
 force
Early retirement due to back problems will
 substantially reduce accumulated wealth
Conclusion

A clearer picture is emerging of the heavy
 global and national toll of low back p
 g                                    pain
 (and other MSK conditions)
Important that it is used to argue for
 resources
Also important to keep up the ‘back room’
 efforts to improve how this burden is
 measured
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