WISC 2016 - World Allergy Organization

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WISC 2016 - World Allergy Organization
WISC 2016
WAO INTERNATIONAL SCIENTIFIC CONFERENCE 2016
6-9 December 2016
Jerusalem, Israel
Outstanding Allergy, Clinical Immunology and Cultural Heritage

PRELIMINARY PROGRAM
                                                                             Registration
                                                                             and Abstract
                                                                              Submission
                                                                              Now Open!

                   www.worldallergy.org/wisc2016

                   www.facebookcom/worldallergyorg            @worldallergy

A meeting of the    In collaboration with   and their mutually collaborating partner
WISC 2016 - World Allergy Organization
WISC 2016 - World Allergy Organization
Invitation to Participate
Dear Colleagues,
We are delighted to invite you to participate in the WAO International Scientific Conference (WISC 2016) in Jerusalem, Israel,
6-9 December 2016. The theme of the Conference is Outstanding Allergy, Clinical Immunology and Cultural Heritage.
As a global alliance of national and regional allergy, asthma and clinical immunology societies, WAO is proud to partner with
the Israel Association of Allergy and Clinical Immunology (IAACI) and their mutually collaborating partner Allergists for Israel
(AFI) to host WISC 2016.
The WAO International Scientific Conference has grown and evolved from one edition to the next, and the meeting in
Jerusalem will continue to build on the hugely successful preceding Conferences in Dubai, United Arab Emirates (2010),
Hyderabad, India (2012), and Rio de Janeiro, Brazil (2014). Delegates may count on a diverse and stimulating scientific
program, highly relevant to both the theory and practice of allergy, asthma and clinical immunology.
WAO organizes these scientific Conferences in recognition of:
• The increasing prevalence and more complex forms of allergic diseases and asthma worldwide, especially in children
• The need to create a more integrated approach to the diagnosis and management of allergic diseases and asthma
• The need to expand the knowledge and practice of allergy and provide more practical knowledge to young professionals
The 2016 Conference on Outstanding Allergy, Clinical Immunology and Cultural Heritage will provide a forum for the most
useful combination of the latest research, review of current theory and practice, and hands-on, problem-based learning. Our
aim is that participants gain insight into the most effective advances in the diagnosis and management of complex and severe
allergies and asthma and in their preventive strategies.
We look forward to seeing you in Jerusalem, Israel!

 Mario Sánchez Borges                       Ignacio J. Ansotegui                    Lanny J. Rosenwasser                  Nancy Agmon-Levin                          Jonathan A. Bernstein
WAO President Conference                    WAO President-Elect                      WAO Past-President                      IAACI President                             AFI President
       President                              Conference Chair                                                            Chair, Local Organizing
                                                                                                                                Committee

                            Abstract Submission and Online Registration Now Open!
                Check the Conference website for frequent updates: www.worldallergy.org/wisc2016

TABLE OF CONTENTS
About WAO................................................................................ 2      Program At-A-Glance................................................................. 6
About IAACI................................................................................ 2    WISC 2016 Keynote Speakers.................................................. 10
About AFI................................................................................... 2   Preliminary Scientific Program—Tuesday, 6 December.......... 12
Conference Information............................................................ 3             Preliminary Scientific Program—Wednesday, 7 December.... 14
Scientific Program Information.................................................. 3               Preliminary Scientific Program—Thursday, 8 December........ 16
What-to-Know . ......................................................................... 4       Preliminary Scientific Program—Friday, 9 December............. 18
Abstract Submission – Now Open!............................................ 5                    Registration.............................................................................. 19
                                                                                                 Accommodations..................................................................... 20

                                                                                                                     WISC 2016 6-9 December 2016 Jerusalem, Israel                               1
WISC 2016 - World Allergy Organization
About WAO
    The World Allergy Organization (WAO) is an international alliance of 97 regional and national allergy,
    asthma and clinical immunology societies. Through collaboration with the Member Societies,
    WAO provides a wide range of educational and outreach programs, symposia and lectureships
    to allergists/immunologists around the globe and conducts initiatives relating to clinical practice,
    service provision, and physician training in order to better understand and address the challenges
    facing allergists/immunologists worldwide.

    About IAACI
    The Israel Association for Allergy and Clinical Immunology (IAACI), founded in 1949, is a non-profit
    association, with a mission to promote education, good clinical practice and research in a wide
    spectrum of allergic and immune mediated diseases in Israel, under the umbrella of the Israel Medical
    Association (IMA). The IAACI is dedicated to promoting collaborations between Allergists/Clinical
    Immunologists and physicians from other disciplines in Israel, aiming to expand knowledge and
    improve patient care. This is achieved by promoting joint meetings and producing Israeli collaborative
    recommendations on various topics.

    About AFI
    Allergists for Israel (AFI) was founded in 1984 and the evolving vision of the group is to develop
    camaraderie of Allergists/Immunologists and other supporters of allergy by gathering in the USA,
    Israel and around the world. AFI strives to establish collegial relations between America and Israel.

    2016-2017 WAO
    BOARD OF DIRECTORS                             CONFERENCE COMMITTEES
    Mario Sánchez Borges, President, Venezuela     Conference President                      Lanny J. Rosenwasser, United States
    Ignacio J. Ansotegui, President-Elect, Spain   Mario Sánchez Borges, Venezuela           Mario Sánchez Borges, Venezuela
    Motohiro Ebisawa, Secretary-General, Japan                                               William Silvers, United States
                                                   Steering Committee
    Francesca Levi-Schaffer, Treasurer, Israel                                               Mario Zernotti, Argentina
                                                   Nancy Agmon-Levin, Israel
    Lanny J. Rosenwasser, Past-President, United
                                                   Ignacio J. Ansotegui, Spain               Scientific Program Committee
      States
                                                   Jonathan A. Bernstein, United States      Ignacio J. Ansotegui, Co-Chair, Spain
    Ruby Pawankar, Historian, Japan
                                                   Leonard Bielory, United States            Claus Bachert, Co-Chair, Belgium
    Mübeccel Akdis, Switzerland
                                                   Motohiro Ebisawa, Japan                   Jonathan A. Bernstein, Co-Chair, United States
    Suwat Benjaponpitak, Thailand
                                                   Aharon Kessel, Israel                     Nancy Agmon-Levin, Israel
    Sergio Bonini, Italy
                                                   Ruby Pawankar, Japan                      Mübeccel Akdis, Switzerland
    Wesley Burks, United States
                                                   Lanny J. Rosenwasser, United States       Leonard Bielory, United States
    Luis Caraballo, Colombia
                                                   Menachem Rottem, Israel                   Sergio Bonini, Italy
    Zeinab Awad El-Sayed, Egypt
                                                   Mario Sánchez Borges, Venezuela           Wesley Burks, United States
    Stanley Fineman, United States
    Paul Greenberger, United States                                                          Luis Caraballo, Colombia
                                                   Local Organizing Committee
    Elham Hossny, Egypt                                                                      Ilan Dalal, Israel
                                                   Nancy Agmon-Levin, Chair, Israel
    Jose Antonio Ortega-Martell, Mexico                                                      Motohiro Ebisawa, Japan
                                                   Ilan Dalal, Israel
    Hirohisa Saito, Japan                                                                    Roy Gerth van Wijk, Netherlands
                                                   Alon Hershko, Israel
    Mimi Tang, Australia                                                                     Edgardo Jares, Argentina
                                                   Yitzhak Katz, Israel
    Mario Zernotti, Argentina                                                                Yitzhak Katz, Israel
                                                   Aharon Kessel, Israel
    Luo Zhang, China                                                                         Gideon Lack, United Kingdom
                                                   Yossi Mekori, Israel
                                                                                             Francesca Levi-Schaffer, Israel
                                                   Menachem Rottem, Israel
    2013-2016 IAACI                                Valery Teplitsky, Israel
                                                                                             Richard Lockey, United States
    BOARD OF DIRECTORS                                                                       Dean Metcalfe, United States
                                                   Organizing Committee                      Josh Milner, United States
    Nancy Agmon-Levin, President, Israel           Ignacio J. Ansotegui, Spain               Ruby Pawankar, Japan
    Ilan Dalal, Past President, Israel             Jonathan A. Bernstein, United States      Susan Prescott, Australia
    Aharon Kessel, Secretary, Israel               Motohiro Ebisawa, Japan                   Nelson Rosário Filho, Brazil
    Valery Teplitsky, Treasurer, Israel            Stanley Fineman, United States            Lanny J. Rosenwasser, United States
    Alon Hershko, Member, Israel                   Roy Gerth van Wijk, Netherlands           Marc Rothenberg, United States
                                                   Lyndon Mansfield, United States           Hugh Sampson, United States
                                                   Ruby Pawankar, Japan                      Mario Sánchez Borges, Venezuela
                                                   Nelson Rosário Filho, Brazil              Dana Wallace, United States

2        WISC 2016 6-9 December 2016 Jerusalem, Israel
WISC 2016 - World Allergy Organization
Conference Information
KEY REASONS TO ATTEND:                                         OBJECTIVES:
Be on the leading edge of medical education and learning!      • To provide insights into the fundamentals and
• Attend state-of-the-art lectures by world experts on           mechanisms of allergic/immunologic diseases by
  allergy, asthma and clinical immunology                        reviewing and evaluating the origins and severity of each
                                                                 disease
• Participate in practical, clinic-friendly workshops on
  Immunotherapy, Food Allergy, Anaphylaxis, Skin Allergies,    • To highlight the most recent advances in the treatment
  Drug Allergy, Asthma, Rhinitis, COPD, Sleep Disorders,         and prevention of allergic and immunological diseases
  and more                                                     • To provide an integrated approach to the diagnosis and
• Network with others in your field and areas of interest        management of severe and more complex forms of
  including: Asthma, Allergy, Immunology, Pediatrics,            allergies
  Pulmonology, Ophthalmology, Gastroenterology,                • To identify unmet needs and areas of research priorities
  Dermatology and ENT
• Showcase your own achievements to key international          WHO SHOULD ATTEND:
  opinion leaders and interact with international and          The Conference will be attended by delegates from all over
  regional colleagues                                          the world. Delegates will be specialists, general practitioners,
                                                               researchers, and other allied health professionals with
                                                               interest in:
                                                               •   Allergy			                        •   Immunology
                                                               •   Asthma			                         •   Ophthalmology
                                                               •   Dermatology			                    •   Pediatrics
                                                               •   ENT				                           •   Pulmonology
                                                               •   Gastroenterology		                •   Family Practice

Scientific Program Information
CME                                                            ABSTRACTS
More information regarding CME will be announced later         ABSTRACT SUBMISSION NOW OPEN!
in 2016. Please visit www.worldallergy.org/wisc2016 for        WISC 2016 invites you to submit an abstract to be considered
frequent updates.                                              for inclusion in the Scientific Program. Accepted abstracts will
                                                               be presented in thematic Poster Sessions.
SESSION TYPES                                                  Please visit www.worldallergy.org/wisc2016 to view
PLENARY SESSIONS                                               submission guidelines.
Plenary presentations will set the stage with context and
background through overviews and literature reviews to         NOTIFICATION OF ACCEPTANCE
define unmet needs.                                            Notification of acceptance/rejection will be emailed
                                                               September 2016. The Presenting Author will receive all
KEYNOTE LECTURES                                               correspondence regarding abstract status, presentation
Keynote Lectures offer attendees the opportunity to attend     type, and date and time, via the email that is provided in the
a lecture on a specific topic from one of the key opinion      abstract submission.
leaders in the field.
                                                               REGISTRATION
SYMPOSIA                                                       The Presenting Author must register for WISC 2016.
Symposia will address specific topics, providing the           Registration now open!
opportunity for in-depth and detailed exploration.
                                                               TRAVEL AND ACCOMMODATIONS
POSTER SESSIONS                                                Abstract presenters are responsible for arranging and
Accepted abstracts will be presented during Poster Sessions.   covering all costs related to registration, travel and hotel
Presenting Authors will stand with their posters, answer       accommodations.
questions and discuss their research.
                                                               TRAVEL GRANTS
                                                               Successful awardees must have an accepted WISC 2016
                                                               abstract submission (abstract submission notifications will
                                                               be sent in September 2016). Awarded Travel Grant funds
                                                               are non-transferrable. If you receive an award and your
                                                               attendance status for the Conference changes for any
                                                               reason, your award is forfeited. Please visit the WISC 2016
                                                               website (www.worldallergy.org/wisc2016) for a Travel Grant
                                                               application.

                                                                             WISC 2016 6-9 December 2016 Jerusalem, Israel        3
WISC 2016 - World Allergy Organization
What-to-Know
    DRESS                                                              necessarily best, methods or procedures appropriate for
    Dress for the Conference is business casual.                       the medical situations discussed, but rather are intended
                                                                       to present an approach, view, statement, or opinion of
                                                                       the faculty that may be helpful to others who face similar
    EVENTS                                                             situations.
    The WAO International Scientific Conference (WISC) 2016
    invites delegates to participate in the following special
    events. Events have been created to give delegates the
                                                                       LANGUAGE
    opportunity to network.                                            The official language of the Conference is English. All
                                                                       sessions will be conducted in English.
    WISC OPENING CEREMONY*
    6 December 2016                                                    NO SMOKING POLICY
    18:00 – 19:30                                                      Smoking is not permitted during any meeting activity or
    Ussishkin Auditorium, Main Level, ICC Jerusalem                    event.
    *Conference Badge Required
    Join fellow delegates, faculty and the WAO Leadership in the       PHOTOGRAPHY
    Ussishkin Auditorium at the ICC Jerusalem for the Opening          By registering to attend WISC 2016, you acknowledge and
    Ceremony to launch the Conference.                                 agree that official photographs taken during the Conference
    WISC 2016 WELCOME RECEPTION*                                       may be used for future WAO meeting promotional purposes
    6 December 2016                                                    and may be shared in the Conference Photo Gallery and post
    19:30 – 21:00                                                      event news updates. Please contact the WAO Secretariat if
    Agam Foyer, ICC Jerusalem                                          you have any concerns with this policy. Personal photography
    *Conference Badge Required                                         is allowed, but please refrain from flash photography during
                                                                       the sessions.
    EVENT TICKETS FOR GUESTS
    If you would like to bring a guest to the Opening Ceremony         SOCIAL MEDIA
    and Welcome Reception, please visit the WISC 2016                  WAO’s social media allows you to interact and stay
    Registration site to purchase tickets: www.worldallergy.org/       connected with WAO and other attendees before, during and
    wisc2016/registration.                                             after the meeting.
                                                                       Use the hashtag #WISC2016 for your comments, questions,
    EXHIBIT HALL                                                       photos or to see what everyone else is talking about.
    A commercial exhibition will take place during the
    Conference on the following dates and times*                       Twitter: @worldallergy
                                                                       Facebook: facebook.com/worldallergyorg
    6 December 2016: 14:30 - 21:00                                     LinkedIn: linkedin.com/company/world-allergy-organization
    7 December 2016: 10:30 - 17:00                                     Instagram: @worldallergyorg
    8 December 2016: 10:30 – 15:30
    *Times are subject to change
                                                                       VENUE
                                                                       The venue of WISC 2016 is:
    GUESTS AND CHILDREN
    Guests and children will not be allowed to attend any portion of   ICC Jerusalem - International Convention Center
    the Scientific Program or Exhibition of WISC 2016.                 PO 6001 Jerusalem 9106001

    INSURANCE/LIABILITIES AND
    DISCLAIMER
    WAO will not be held liable for personal injuries or for loss of
    or damage to property incurred by participants or guests at
    WISC 2016, including those participating in tours and related
    events. Participants and guests are encouraged to purchase
    insurance to cover loss incurred in the event of cancellation,
    medical expenses or damage to or loss of personal effects
    when traveling.
    WAO cannot be held liable for any hindrance or disruption of
    WISC 2016 proceedings arising from natural, political, social
    or economic events or other unforeseen incidents beyond its
    control. Registration of a participant implies acceptance of
    this condition.
    The materials presented at this continuing medical education
    activity are made available for educational purposes only.
    The materials are not intended to represent the only, nor

4        WISC 2016 6-9 December 2016 Jerusalem, Israel
WISC 2016 - World Allergy Organization
Abstract Submission – Now Open!
Abstract Submission Deadline: 31 July 2016                                        TRAVEL GRANTS
WISC 2016 invites you to submit an abstract to be considered                      WAO would like to recognize our Junior Members, by
for inclusion in the WISC 2016 Scientific Program. Accepted                       extending the opportunity to apply for a Travel Grant to
abstracts will be presented in thematic Poster Sessions on                        attend WISC 2016. In order to receive a Travel Grant the
6-8 December 2016.                                                                individual must:
Online submission is now open. Please visit www.                                  • Be within five (5) years of your latest degree
worldallergy.org/wisc2016 to view submission guidelines and                       • Or be 35 years of age or younger
to submit an abstract.
                                                                                  • Submit and have accepted an abstract presented at the
NOTIFICATION OF ACCEPTANCE                                                          Conference
Notification of acceptance/rejection will be emailed                              Please visit www.worldallergy.org/wisc2016/scientific-
September 2016. The Presenting Author will receive all                            program/abstracts to submit your abstract and to review the
correspondence regarding the abstract status, presentation                        Travel Grant application, guidelines and instructions.
type, date and time, via the email that is provided in the                        Travel Grant Awardees will receive:
abstract submission.
                                                                                  • Up to three (3) nights’ accommodations at the
                                                                                    Conference appointed hotel
REGISTRATION
The Presenting Author must register for WISC 2016 on/by                           • Complimentary registration
31 August 2016. Registration may be done online at www.                           • WAO Certificate of Award as a Travel Grant recipient
worldallergy.org/wisc2016/registration                                            If you have any questions in regards to the abstract or travel
                                                                                  grant please email wisc@worldallergy.org. Travel grant
TRAVEL                                                                            recipients will be notified in September 2016. We look
Abstract presenters are responsible for arranging and paying                      forward to your participation at WISC 2016.
for their own registration, travel and hotel accommodations.
Accommodations can be made at www.worldallergy.org/
wisc2016/accommodation

               Go Global with the
           WAO Junior Members Group
                             JOIN TODAY!
                         www.worldallergy.org/juniormembers

      Help shape the                             Who Qualifies to Be a WAO Junior Member?
        future of WAO                             • Working in the field of allergy/clinical immunology
       through global                             • Under 35 years of age or within 5 years of a training program in
       advocacy and                                 allergy, asthma, clinical immunology or related field
      leadership as a                             • A current member of a WAO Member Society
      Junior Member

                The WAO Junior Members Group is a network of young allergists / clinical
               immunologists and scientists who interact with WAO to identify the key issues
               affecting the world’s up-and-coming allergy practitioners and to advise on ways to
               help meet their educational and training needs.

                                                                                                    WISC 2016 6-9 December 2016 Jerusalem, Israel   5
WISC 2016 - World Allergy Organization
Program At-A-Glance
    TUESDAY, 6 DECEMBER 2016
     8:30                                                                          Keynote Lecture
                                             The Mucosal Leukotriene E4 Receptor CysLT3R Regulates Secretion and Responds to the Mast Cell
     8:45

     9:00

     9:15

     9:30                                                                             Plenary
                                                                              Mechanisms of Allergenicity
     9:45

    10:00

    10:15

    10:30
                                                                                     Coffee Break
    10:45

    11:00
                                                                                                                                                            Workshop
    11:15                                                                                                                                               Can Monoclonal
                                                                                                                          SLaai Sister Society
                                                                                                   Symposium                                            Antibodies Really
    11:30                                                               Symposium                                            Symposium:
                 Symposium                   Symposium                                        The Microbiome and                                      be Useful Weapons
                                                                  Development of Allergen                                   Latin American
               Mast Cell Diseases       Update on Aeroallergens                               Its Role in Health and                                   in Treating Allergic
    11:45                                                          Immunotherapy (AIT)                                  Peculiarities on Allergic
                                                                                                      Disease                                        Diseases as They are In
                                                                                                                               Diseases
    12:00                                                                                                                                           Cancer and Autoimmune
                                                                                                                                                            Diseases?
    12:15

    12:30

    12:45
                                                                                    Poster Sessions
    13:00

    13:15

    13:30

    13:45                                                                                   Junior Member Practical
                                                                                                     Course               ACAAI Sister Society
    14:00                                                              Symposium
                 Symposium                   Symposium                                       Diagnostic Work-Up of           Symposium:                    Workshop
                                                                  Aerobiology and Climate
            Emerging Cells in Allergy      Chronic Urticaria                                  Respiratory Allergies:     Expanding the Role of           Food Allergy II
    14:15                                                                 Change
                                                                                                From Skin Test to            the Allergist
    14:30                                                                                    Functional Assessment

    14:45

    15:00
                                                                                     Coffee Break
    15:15

    15:30

    15:45
                 Symposium
    16:00                                                               Symposium                                                                         Workshop
             Mast Cell ICON: Mast            Symposium                                        Company Sponsored              Sister Society
                                                                    The Microbiome and                                                               A New Frontier for the
              Cells in Health and       Hereditary Angioedema                                    Symposium                    Symposium
    16:15                                                             Airway Diseases                                                                      Allergist
                    Diseases
    16:30

    16:45

    17:00

    17:15

    17:30

    17:45

    18:00

    18:15                                                                      OPENING CEREMONY
                                                                      (Welcome Reception to immediately follow)
    18:30

    18:45
    19:00

6       WISC 2016 6-9 December 2016 Jerusalem, Israel
WISC 2016 - World Allergy Organization
Program At-A-Glance
WEDNESDAY, 7 DECEMBER 2016
 8:30                                                                       Keynote Lecture
                                                               Eosinophilic Esophagitis: A Rising Concern
 8:45

 9:00

 9:15

 9:30                                                                           Plenary
                                                                  Clinical Aspects of Immunotherapy
 9:45

10:00

10:15

10:30
                                                                              Coffee Break
10:45

11:00
                                                                                                                AAAAI Sister Society
11:15                                                                                                              Symposium:                   Workshop
                                                                Symposium
              Symposium                Symposium                                                                New Concepts in the         Integrative Allergy:
11:30                                                           Usefulness of
         Advances in Pollen       Practical Approaches                                 Company Sponsored       Immunopathogenesis             Complementary
                                                          Inflammatory Markers
        Forecasting to Predict   for the Management of                                    Symposium              and Management           Approaches within an
11:45                                                       in the Treatment of
          Clinical Symptoms          Chronic Urticaria                                                              of Primary           Allergy Asthma Practice:
                                                                  Asthma
12:00                                                                                                           Immunodeficiencies         The USA Experience

12:15

12:30

12:45
                                                                            Poster Sessions
13:00

13:15

13:30

13:45                                  Symposium
                                      Navigating the                                                              Junior Member
                                                              Symposium                    Symposium
14:00        Symposium                Landscape of                                                                Practical Course
                                                          Mold Allergy: Is it Real    What Really Happens                                     Workshop
        New and Old Hyper- IgE   Angioedema Conditions:                                                         Challenge Tests and
                                                          and What Do We Do           during Food-Triggered                                Immune Deficiency
14:15        Syndromes               Recognition and                                                           Desensitization in Food
                                                               About It?                   Anaphylaxis
                                     Management of                                                                and Drug Allergy
14:30                             Angioedema Subtypes

14:45

15:00
                                                                              Coffee Break
15:15

15:30
                                                                 Symposium
15:45                                                              Beyond
                                                          Pharmacotherapy: Role                                KAAACI Sister Society          Workshop
16:00      Symposium
                                      Symposium           of Lifestyle Modification    Company Sponsored           Symposium:               When Allergy and
        Immuno­dysregulatory
                                      Drug Allergy        in Managing Asthma as           Symposium              Environment and           Immune Deficiency
16:15       Disorders
                                                           a Human Condition in                                 Respiratory Allergies           Meet
16:30                                                      the Age of Technology
                                                                and Outcomes
16:45

17:00

                                                                                                      WISC 2016 6-9 December 2016 Jerusalem, Israel                 7
WISC 2016 - World Allergy Organization
Program At-A-Glance
    THURSDAY, 8 DECEMBER 2016
     8:30                                                                        Keynote Lecture
                                                                    The Ubiquitin System in Health and Disease
     8:45

     9:00

     9:15

     9:30                                                                            Plenary
                                                                                 Atopic Dermatitis
     9:45

    10:00

    10:15

    10:30
                                                                                    Coffee Break
    10:45

    11:00

    11:15
                                            Symposium                                      Junior Member Practical    TNSACI Sister Society         Workshop
    11:30         Symposium                                           Symposium
                                        Primary Prevention of                                        Course                Symposium:          Non-Allergic Rhinitis
               Otitis Media with                                  Severe Asthma (COSA
                                        Atopy and Childhood                                Practical Management of   Specific Immunotherapy:    (NAR), Cough and
    11:45           Effusion                                            Session)
                                              Asthma                                              Anaphylaxis           Bench to Bedside         Asthma Practice
    12:00

    12:15

    12:30

    12:45
                                                                                  Poster Sessions
    13:00

    13:15

    13:30

    13:45                                                                                                              CSACI Sister Society
                                                                                                                           Symposium:
    14:00         Symposium                 Symposium                 Symposium                                         Anaphylaxis, Birth
                                                                                             Company Sponsored                                      Workshop
            Update on Eosinophilic     Desensitization to Drugs   Asthma in the Elderly                               Cohorts, Development
                                                                                                Symposium                                          Anaphylaxis
    14:15   Gastrointestinal Disease       & Anaphylaxis                Today                                          and Eosinophils: The
                                                                                                                        ABC’s of Canadian
    14:30                                                                                                                Allergy Research

    14:45

    15:00
                                                                                    Coffee Break
    15:15

    15:30

    15:45                                                                                                               Junior Member
                 Symposium                                                                       Symposium                 Symposium
                                            Symposium
    16:00       Treatment and                                         Symposium             Aberrant Inflammation      What’s Going on in
                                       Chronic Rhinosinusitis:                                                                                    Sister Society
            Management Advances                                   Asthma and Poverty:       and Aberrant Immune        Allergy and Clinical
                                         From Endotypes to                                                                                         Symposium
    16:15    in Ocular Allergy and                                What Can Be Done?          Programming in Early     Immunology: Junior
                                       Personalized Treatment
            Other Surface Diseases                                                                   Life             Members at the Front
    16:30                                                                                                                      Line

    16:45

    17:00

8       WISC 2016 6-9 December 2016 Jerusalem, Israel
Program At-A-Glance
FRIDAY, 9 DECEMBER 2016
 8:30                                                                           Keynote Lecture
                                               Perturbing Early Life Microbiota Development and Its Immunologic Consequences
 8:45

 9:00

 9:15

 9:30                                                                               Plenary
                                                The Next Frontier for Food Desensitization: Alternatives to Oral Immunotherapy
 9:45

10:00

10:15

10:30
                                                                                   Coffee
10:45

11:00

11:15
             Symposium                                                                                             Junior Member Practical
11:30                                   Symposium                 Symposium
         Use of Environmental                                                                 Symposium                     Course           Sister Society
                                    Phenotypes in Chronic       Severe Asthma in
        Control to Treat Allergic                                                             Food Allergy         Allergy Immunotherapy:     Symposium
11:45                                  Rhinosinusitis               Children
               Disorders                                                                                            What, When and How
12:00

12:15

12:30

                                                                                                        WISC 2016 6-9 December 2016 Jerusalem, Israel         9
WISC 2016 Keynote Speakers
 TUESDAY, 6 DECEMBER
                          The Mucosal Leukotriene E4 Receptor CysLT3R Regulates Secretion and Responds to the Mast Cell |
                          Frank Austen (United States)
                          K. Frank Austen attended Amherst College and Harvard Medical School and served his house
                          staff training years at the Massachusetts General Hospital (MGH). He established an independent
                          laboratory at the MGH in 1962 and moved to the Robert B. Brigham in 1966 to establish a
                          Department of Rheumatology and Immunology which evolved into a department of the Brigham
                          and Women’s Hospital (BWH). After chairing this Department for 25 years, he shifted to the
                          AstraZeneca Professorship of Respiratory and Inflammatory Diseases. Austen has pioneered
                          many aspects of innate immunity/inflammation through an in depth focus on the functions and
                          regulation of arachidonic acid metabolism to the cysteinyl leukotrienes (cysLTs), the pathways for the
                          development and phenotypic diversity of mast cells, and the pattern recognition path for activation
                          of the alternative complement activating pathway which also serves to amplify the classical
 complement pathway.
 Austen was elected to the National Academy of Sciences and to the American Academy of Arts and Sciences in 1974 and as a
 foreign member of the Royal Society (UK) in 2004. He has served as President of the American Association of Immunologists,
 the American Academy of Allergy, Asthma and Immunology, and the American Association of Physicians.

 WEDNESDAY, 7 DECEMBER
                          Eosinophilic Esophagitis: A Rising Concern | Marc Rothenberg (United States)
                            Marc Rothenberg is the Director of the Division of Allergy and Immunology at Cincinnati Children’s
                            Hospital Medical Center (Cincinnati Children’s), a tenured Professor of Pediatrics at Cincinnati
                            Children’s and the University of Cincinnati College of Medicine (UCCOM), the Founder and Director
                            of the Cincinnati Center for Eosinophilic Disorders (CCED), and the Founder and Director of the
                            NIH--‐sponsored, national Consortium of Eosinophilic Disease Researchers (CEGIR). He graduated
                            summa cum laude with Highest Honors in Chemistry and Biochemistry from Brandeis University. At
                            Harvard Medical School (HMS), he completed the combined MD/PhD program. His PhD under the
                            mentorship of Dr. Frank Austen included seminal studies on eosinophil hematopoiesis, identifying
                            and characterizing the original biology of eosinophilopoeitins, which led to the development
                            of a new class of drugs (humanized anti--‐IL--‐5). After completing a residency in pediatrics at
                            Children’s Hospital in Boston, Dr. Rothenberg did a combined fellowship in Allergy/Immunology and
 Hematology at Children’s Hospital in Boston. Rothenberg did post--‐doctorate training in the genetics laboratory of Dr. Philip
 Leder at HMS, where he cloned the eotaxin chemokine, which opened up a new direction in allergy research. He came to the
 UCCOM and Cincinnati Children’s in 1996 and has helped build a top program in pediatric research; his division is a leader
 in pediatric allergy and immunology. His research is focused on molecular analysis of allergic inflammation, primarily on the
 pathogenesis of eosinophilic gastrointestinal disorders (EGIDs). His laboratory takes multi--‐disciplinary approaches including
 the development of preclinical murine models of allergic disease, genetics, genomics, molecular immunology, cellular biology,
 and biochemistry.
 Dr. Rothenberg’s awards include the 2007 E. Mead Johnson Award from the Society of Pediatric Research, an NIH MERIT
 Award in 2010 and he is a member of the Hewlett--‐ Woodmere Alumni Hall of Fame. He is an elected member of the ASCI,
 AAP, AAAS and SPR. His publications number over 325. He has served on various review panels for journals and grant agencies
 including the NIH, Burroughs Trust, the MRC of the UK and the ISF of Israel. He is an Associate Editor of the Journal of Allergy
 and Clinical Immunology, and Mucosal Immunology, and co--‐Section Head of the Allergy and Hypersensitivity Section of
 Faculty 1000. He has served a four--‐year term on the Advisory Council of the NIAID. His research has been supported by
 numerous sources including the NIH, Human Frontier Science Program Organization, the Burroughs Wellcome Fund, the Dana
 Foundation, the US Department of Defense, US--‐Israel Binational Fund, and PCORI. He has trained a myriad of clinical and
 research investigators in his own laboratory and also as Program Director and/or Co--‐Principal Investigator of several NIH
 training grants including the NIH CTSA KL2, NICHD CHRCDA K12, and NIAID T32.

10    WISC 2016 6-9 December 2016 Jerusalem, Israel
WISC 2016 Keynote Speakers
THURSDAY, 8 DECEMBER
The Ubiquitin System in Health and Disease | Avram Hershko (Israel)
Nobel Laureate in Chemistry (2004)
                           Avram Hershko was born in 1937 in Hungary and emigrated with his family to Israel in 1950. He
                           gained his MD (1965) and PhD (1969) from the Hebrew University - Hadassah Medical School of
                           Jerusalem. After a post-doctoral fellowship at the University of California of San Francisco (1969-72),
                           he joined the faculty of the Haifa Technion becoming professor in 1980. He is now Distinguished
                           Professor in the Unit of Biochemistry in the B. Rappaport Faculty of Medicine of the Technion. His
                           main research interests concern the mechanisms by which cellular proteins are degraded, a formerly
                           neglected field of study. Hershko and his colleagues showed that cellular proteins are degraded by a
                           highly selective system. This system tags proteins for destruction by linkage of a protein called
                           ubiquitin, which had previously been identified in many tissues, as the name suggests, but whose
                           function was previously unknown. Subsequent work in Hershko’s and many other laboratories has
                           shown that the ubiquitin system has a vital role in controlling a wide range of cellular processes,
                           such as the regulation of cell division, signal transduction and DNA repair. Abnormalities in the
ubiquitin system result in diseases such as certain types of cancer. The full range of functions of the ubiquitin system in health
and disease has still to be elucidated.
Hershko was awarded the Nobel Prize in Chemistry (2004) jointly with his former PhD student Aaron Ciechanover and his
colleague Irwin Rose. His many other honors include the Israel Prize for Biochemistry (1994), the Gairdner Award (1999), The
Alfred P. Sloan Prize of the General Motors Cancer Research Foundation (2000), the Lasker Prize for Basic Medical Research
(2000), the Wolf Prize for Medicine (2001) and the Louisa Gross Horwitz Award (2001). Hershko is a member of the Israel
Academy of Sciences (2000) and a Foreign Associate of the US Academy of Sciences (2003).

FRIDAY, 9 DECEMBER
                          Perturbing Early Life Microbiota Development and Its Immunologic Consequences | Martin J. Blaser
                          (United States)
                          Martin J. Blaser is the Muriel and George Singer Professor of Medicine, Professor of Microbiology,
                          and Director of the Human Microbiome Program at the NYU School of Medicine. He served as
                          Chair of the Department of Medicine at NYU from 2000-2012. A physician and microbiologist, Dr.
                          Blaser is interested in understanding the relationships we have with our persistently colonizing
                          bacteria. His work over 30 years focused on particular organisms, including Campylobacter species
                          and Helicobacter pylori, which also are model systems for understanding the interactions of
                          residential bacteria with their human hosts. Over the last 15 years, he has been actively studying
                          the relationship of the human microbiome with health and with such important diseases as asthma,
                          obesity, diabetes, and allergies.
                          Over the course of his career, Dr. Blaser has served as the advisor for a large number of students,
post-doctoral fellows, and junior faculty. He served as President of the Infectious Diseases Society of America, Chair of
the Board of Scientific Counselors of the National Cancer Institute, Chair of the Advisory Board for Clinical Research of the
National Institutes of Health, and on the Scientific Advisory Board of the Doris Duke Charitable Foundation. He was elected
to the National Academy of Medicine and the American Academy for Arts and Sciences. He holds 25 U.S. patents relating to
his research, and has authored over 540 original articles. Recently, he wrote “Missing Microbes”, a book targeted to general
audiences. He now is serving as the Chair of the Presidential Advisory Council for Combating Antibiotic-Resistant Bacteria.

                                                                               WISC 2016 6-9 December 2016 Jerusalem, Israel     11
Preliminary Scientific Program—Tuesday, 6 December
 KEYNOTE                                                                                                             08.30 – 09.00
 The Mucosal Leukotriene E4 Receptor CysLT3R Regulates Secretion and Responds to the Mast Cell | Frank Austen (United States)

 PLENARY                                                                                                             09.00 – 10.30
 Mechanisms of Allergenicity
 The Evolutionary Roots of Allergenicity | Kathleen Barnes (United States)
 Recent Discoveries on Molecular Intrinsic Allergenic Properties | Rudolf Valenta (Austria)
 IgG4 to Environmental Antigens in Healthy and Allergic Children | Paolo Maria Matricardi (Germany)

 COFFEE BREAK                                                                                                        10.30 – 11.00

 SYMPOSIA                                                                                                            11.00 – 12.30
 Mast Cell Diseases
 The Many Faces of Mast Cell Clonal Diseases | Dean Metcalfe (United States)
 Mast Cell Activation Syndrome | Alon Hershko (Israel)
 Prognosis and Management of Diseases of Mast Cell Activation and Proliferation | Mariana Castells (United States)
 Development of Allergen Immunotherapy (AIT)
 Mechanisms of Early Desensitization: Histamine Receptors and More | Natalija Novak (Germany)
 Role of B Reg Cells in Allergen Tolerance during Allergen Immunotherapy (AIT) | Mübeccel Akdis (Switzerland)
 Rapid Suppression of IgE-Mediated Allergy | Fred Finkelman (United States)
 Update in Aeroallergens
 Pollen and Fungal Allergens | Jay Portnoy (United States)
 Mite and Cockroach Allergens | Luis Caraballo (Colombia)
 Regulatory Aspects of Immunotherapy | Sergio Bonini (United Kingdom)
 The Microbiome and Its Role in Health Disease
 Barrier Function and Microbiotic Dysbiosis in Atopic Dermatitis | Michael Levin (South Africa)
 Early Life Microbiome Dysbiosis and Development of Allergy | Christine Johnson (United States)
 Late Onset Airway Disease: Role of Viruses and Bacteria | Peter Le Souëf (Australia)

 WORKSHOP                                                                                                            11.00 – 12.30
 Can Monoclonal Antibodies Really be Useful Weapons in Treating Allergic Diseases as they are in Cancer and Autoimmune
 Diseases?
 Cancer and Monoclonal Antibodies | Erika Jensen-Jarolim (Austria)
 Autoimmune Diseases and Monoclonal Antibodies | TBC
 Allergic Diseases and Monoclonal Antibodies | Francesca Levi-Schaffer (Israel)

 SISTER SOCIETY SYMPOSIUM                                                                                            11.00 – 12.30
 Latin American Society of Allergy, Asthma and Immunology (SLaai) —
 Latin American Peculiarities on Allergic Diseases
 Characteristics of Anaphylaxis Detection and Management | TBC
 Lessons Learnt from Drug Allergy Registries | TBC
 Allergic Rhinitis and Its Impact on Asthma (ARIA) Achievements and Future Needs | TBC

 POSTER SESSIONS                                                                                                     12.30 – 13.30

12     WISC 2016 6-9 December 2016 Jerusalem, Israel
Preliminary Scientific Program—Tuesday, 6 December
SYMPOSIA                                                                                                             13.30 – 15.00
Emerging Cells in Allergy
Role of Mast Cells in Innate Inflammation | Hideaki Morita (Japan)
Lymphoid Cells, Effector Cells and Immune Responses | Judah Denburg (Canada)
Macrophages & Neutrophils | Lorenzo Moretta (Italy)
Aerobiology and Climate Change
Meteorological Conditions, Climate Change, New Emerging Factors, and Asthma and Related Allergic Disorders: A Statement of the World
Allergy Organization | Menachem Rottem (Israel)
Climate Change and Allergic Respiratory Diseases: An Update for the Allergist | Gennaro D’Amato (Italy)
The Role of Aerobiology in 2016 | Jay Portnoy (United States)
Chronic Urticaria
Classification of Chronic Urticaria: New Aspects | David Lang (United States)
Angioedema—Histamine or Bradykinin? | Avner Reshef (Israel)
Treatment of Patients with Severe Chronic Urticaria | Mario Sánchez Borges (Venezuela)

JUNIOR MEMBER PRACTICAL COURSE                                                                                       13.30 – 15.00
Diagnostic Work-up of Respiratory Allergies: From Skin Test to Functional Assessment
Senior Moderator | TBC
Junior Member | Shira Benor (Israel)
Junior Member | Mariana Couto (Portugal)

WORKSHOP                                                                                                             13.30 – 15.00
Food Allergy II
Diagnosis of Food Allergy | Yael Levy (Israel)
Food Oral Immunotherapy | Yitzhak Katz (Israel)
Baked Milk Immunotherapy | Ilan Dalal (Israel)

SISTER SOCIETY SYMPOSIUM                                                                                             13.30 – 15.00
American College of Allergy, Asthma and Immunology (ACAAI) Symposium -
Expanding the Role of the Allergist
Ocular Allergy ICON: The Eyes Have It | Leonard Bielory (United States)
Asthma COPD Overlap Syndrome (ACOS) | Bryan Martin (United States)
Provocative Challenges | Stephen Tilles (United States)

COFFEE BREAK                                                                                                         15.00 – 15.30

SYMPOSIA                                                                                                             15.30 – 17.00
Mast Cell ICON: Mast Cells in Health & Diseases
Non-IgE Mediated Mast Cell Activation in Disease | Dean Metcalfe (United States)
Mast Cells Beyond Allergy: T Cell-Mast Cell Interaction in Inflammatory Processes | Yoseph Mekori (Israel)
Mast Cells in Allergic Airway Inflammation | Ruby Pawankar (Japan)
Hereditary Angioedema (HAE)
HAE in the Pediatric Population | Aharon Kessel (Israel)
HAE during Pregnancy | Elias Toubi (Israel)
Treatment of HAE in 2016 | Michael Frank (United States)
The Microbiome and Airway Diseases
The Airway Microbiome: Status and Future | Peter Howarth (United Kingdom)
Allergens and Superallergens: The Immune Proteome of Staphylococcus Aureus | Claus Bachert (Belgium)
Microbial Exposures Influence the Risk for Wheezing and Asthma in Urban Children | James Gern (United States)

WORKSHOP                                                                                                             15.30 – 17.00
A New Frontier for the Allergist
Clinical Pearls for Diagnosing Allergic Contact Dermatitis | David Bernstein (United States)
Skin Tests and Other Provocation Tests in Chronic Urticaria | Marcus Maurer (Germany)
Metal Hypersensitivity and Prosthetic Devices | Karin Pacheco (United States)

                                                                                        WISC 2016 6-9 December 2016 Jerusalem, Israel   13
Preliminary Scientific Program—Wednesday, 7 December
 KEYNOTE                                                                                                             08.30 – 09.00
 Eosinophilic Esophagitis: A Rising Concern | Marc Rothenberg (United States)

 PLENARY                                                                                                             09.00 – 10.30
 Clinical Aspects in Immunotherapy
 The Future Directions in Immunotherapy | Giovanni Passalacqua (Italy)
 The New Routes of Administration: Where Do We Stand? | Gabriela Senti (Switzerland)
 Advances in Mechanisms and Clinical Implications | Cezmi Akdis (Switzerland)

 COFFEE BREAK                                                                                                        10.30 – 11.00

 SYMPOSIA                                                                                                            11.00 – 12.30
 Advances in Pollen Forecasting to Predict Clinical Symptoms
 The Relationship between Pollen Concentration and Clinical Symptom Thresholds | Carmi Geller-Bernstein (United States)
 Validation of Pollen Collection and Monitoring Techniques and Clinical Symptom Instruments for Assessing the Impact of Pollen Exposure on
 Patient Health | Santiago Martinez (United States)
 Modeling and Forecasting Pollen for Allergy Prevention | Carsten Skjøth (United Kingdom)
 Usefulness of Inflammatory Markers in the Treatment of Asthma
 Novel Aspects of Inflammation in Asthma: Future Approaches | Fernan Caballero-Fonseca (Venezuela)
 Inflammatory Markers for Asthma Diagnosis and Follow-up | Nelson Rosário Filho (Brazil)
 Targeted Therapies for Asthma: State of the Art | Walter Canonica (Italy)
 Practical Approaches for the Management of Chronic Urticaria
 Mechanisms of Chronic Urticaria: Do We Understand the Whole Landscape? | Jonathan Bernstein (United States)
 Diagnostic, Quality of Life and Control Tools in Chronic Urticaria | Torsten Zuberbier (Germany)
 Treatment of Chronic Urticaria, Guidelines and Beyond | Allen Kaplan (United States)

 WORKSHOP                                                                                                            11.00 – 12.30
 Integrative Allergy: Complementary Approaches within an Allergy Asthma Practice
 What is Integrative Allergy, Integrative Medicine and Complementary and Integrative Medicine (CAM) | William Silvers (United States)
 Evidence Basis for Integrative Modalities | Leonard Bielory (United States)
 Stress and Immune System | TBC

 SISTER SOCIETY SYMPOSIUM                                                                                            11.00 – 12.30
 American Academy of Allergy Asthma & Immulology Symposium
 - New Concepts in the Immunopathogenesis and Management of Primary Immunodeficiencies
 Immune Deficiencies Associated with Early Onset Inflammatory Bowel Disease | Kathleen Sullivan (United States)
 Severe Combined Immune Deficiency: from Newborn Screening to Cellular and Molecular Therapy |
 Luigi Notarangelo (United States)
 The Complex Veiled Among the Common Variables - Addressing the Challenges of the new “CVID-like” Disorders |
 Klaus Warnatz (Germany)

 POSTER SESSIONS                                                                                                     12.30 – 13.30

 SYMPOSIA                                                                                                            13.30 – 15.00
 New and Old Hyper-IgE Syndromes
 Autosomal Dominant Hyper IgE Syndromes (AD-HIES), Phosphoglucomutase 3 (PGM 3) and Dedicator of Cytokinesis 8 (DOCK8) Deficiency |
 Thomas Fleisher (United States)
 A Common Monogenic Cause for the Mast Cell Activation Syndrome | Joshua Milner (United States)
 Hypereosinophilic Syndrome (HES) and Eosinophilic Granulomatosis with Polyangiitis (EGPA) | Michael Wechsler (United States)
 Mold Allergy: Is It Real and What Do We Do About It?
 Fungi: What Are They and What Types of Exposure Do We Have to Them? | Estelle Levetin (United States)
 Health Effects of Fungal Exposure: What is Known | John Cohn (United States)
 Interventions to Reduce Fungal Exposure and Improve Health | James Sublett (United States)

14     WISC 2016 6-9 December 2016 Jerusalem, Israel
Preliminary Scientific Program—Wednesday, 7 December
Navigating the Landscape of Angioedema Conditions: Recognition and Management of Angioedema Subtypes
Idiopathic Angioedema: Histaminergic and Kinin-Mediated | Konrad Bork (Germany)
C1INH Deficiency: Acquired and Hereditary | TBC
Bradykinin Mediated Angioedema with Normal C1INH–ACE-I and Associated and HAE with Normal C1INH | Bruce Zuraw (United States)
What Really Happens during Food Triggered Anaphylaxis
Who Is at Risk of Food-Triggered Anaphylaxis? | Margitta Worm (Germany)
What Drives Symptoms during Acute Allergic Reactions to Food? | Stanley Fineman (United States)
Cardiovascular Changes during Acute Allergic Reactions to Food | Paul Turner (United Kingdom)

JUNIOR MEMBER PRACTICAL COURSE                                                                                           13.30 – 15.00
Challenge Tests and Desensitization in Food and Drug Allergy
Senior Moderator | TBC
Junior Member | TBC
Junior Member | TBC

WORKSHOP                                                                                                                 13:30 – 15.00
Immune Deficiency
Five Decades of Immune Deficiency: A Story to be Told | Amos Etzioni (Israel)
Primary Immunodeficiency | José Antonio Ortega Martell (Mexico)
Newborn Screening for Severe Combined Immunodeficiency (SCID): State of the Art | Raz Somech (Israel)

COFFEE BREAK                                                                                                             15.00 – 15.30

SYMPOSIA                                                                                                                 15.30 – 17.00
Immunodysregulatory Disorders
Inflammasome Related Disorders | Hal Hoffman (United States)
Hereditary Periodic Fever Syndromes | Yackov Berkun (Israel)
Blockers for the Therapy of Auto Inflammatory Diseases | Lanny J. Rosenwasser (United States)
Beyond Pharmacotherapy: Role of Lifestyle Modification in Managing Asthma as Human Condition in the Age of
Technology and Outcomes
The Role of Lifestyles on the Immunology, Physiology, and Quality of Life of Asthma Patients: Is It Time for Artificial Intelligence and Mobile
Health? | Mark Lazarovich (United States)
The Effect of Activity and Weight Modification on Asthma Management | Louis-Philippe Boulet (Canada)
Genetics and Epigenetics of Stress and Asthma | Juan C. Celedon (United States)
Drug Allergy
Beta-Lactam Allergy Evaluation: Do We Have Alternatives? | Luis Felipe Chiaverini Ensina (Brazil)
Desensitization of Biological Drugs | Nancy Agmon-Levin (Israel)
Practical Approach to NSAID Hypersensitivity | Pedro Giavina Bianchi (Brazil)

WORKSHOP                                                                                                                 15.30 – 17.00
When Allergy and Immune Deficiency Meet
Eczema and Asthma in Immune Deficiencies | Kathleen Sullivan (United States)
Food Allergies in Immune Deficiencies | Sara Anvari (United States)
The Peculiar Atopy in Hyper IgE Syndromes | Ricardo Sorensen (United States)

SISTER SOCIETY SYMPOSIUM                                                                                                 15.30 – 17.00
Korean Academy of Asthma, Allergy, and Clinical Immunology Symposium (KAAACI)
- Environment and Respiratory Allergies
The Impact of Air Pollutants on Cell Barriers in Asthma| An-Soo Jang (Korea)
Major Environmental Factors in Children with Allergic Rhinitis - The Korean Experience| Dae Hyun Lim (Korea)
Early Life Origins of Respiratory Disease: Lessons from a Birth Cohort | Allan Becker (Canada)

                                                                                        WISC 2016 6-9 December 2016 Jerusalem, Israel             15
Preliminary Scientific Program—Thursday, 8 December
 KEYNOTE                                                                                                            08.30 – 09.00
 The Ubiquitin System in Health and Disease | Avram Hershko (Israel)

 PLENARY                                                                                                            09.00 – 10.30
 Atopic Dermatitis
 Atopic Dermatitis: Epidemiology and Mechanisms State of the Art | TBC
 Differences between Atopic Dermatitis (AD) Disease Phenotypes and the Need for Personalized Medicine in Atopic Dermatitis | Emma
 Guttman (United States)
 Therapy of Atopic Dermatitis | Torsten Zuberbier (Germany)

 COFFEE BREAK                                                                                                       10.30 – 11.00

 SYMPOSIA                                                                                                           11.00 – 12.30
 Otitis Media with Effusion
 Effusion in the Middle Ear: A Hidden Enemy in School Children (Epidemiological Aspects and Impact on Learning) | Yi Li (China)
 Otitis Media with Effusion (OME) and Atopy: Cause or Myth? (Phsiopathogenic Mechanisms and Relationship) | Nelson Rosário Filho (Brazil)
 Eosinophlic Otitis Media (Diagnostic and Approach Treatment) | Mario Zernotti (Argentina)
 Severe Asthma: COSA Session
 Severe Asthma Phenotypes and Fungal Allergic Respiratory Disease | Paul Greenberger (United States)
 Aspirin Exacerbated Respiratory Disease | Shmuel Kivity (Israel)
 Novel Therapies for Severe - Unresponsive Asthma | Elliot Israel (United States)
 Primary Prevention of Atopy and Childhood Asthma
 Modulation of Early Life Allergic Sensitization for the Prevention of Childhood Asthma | Robert Wood (United States)
 New Insights on the Diagnosis and Treatment of Asthma Exacerbation in Infants under the Age of One Year | Benjamin Volovitz (Israel)
 Vitamins and/or Probiotics Supplementation for Asthma Prevention | Avraham Biegelman (United States)

 JUNIOR MEMBER PRACTICAL COURSE                                                                                     11.00 – 12.30
 Practical Management of Anaphylaxis
 Senior Moderator | TBC
 Junior Member | Vered Schichter-Konfino (Israel)
 Junior Member | Manuel Rial Prado (Spain)

 WORKSHOP                                                                                                           11.00 – 12.30
 Non-Allergic Rhinitis (NAR), Cough and Asthma Practice
 Upper and Lower Airways Relationship and Treatment | Eli Meltzer (United States)
 How Do We Manage Recalcitrant Sinusitis Patients | Michael Kaliner (United States)
 Impact of Sinonasal Disease on the Lower Airways | Larry Borish (United States)

 SISTER SOCIETY SYMPOSIUM                                                                                           11.00 – 12.30
 Turkish National Society of Allergy and Clinical Immunology Symposium (TNSACI)
 - Specific Immunotherapy: Bench to Bedside
 Skin Prick Testing: Optimizing the Practice | Bülent Şekerel (Turkey)
 SCIT vs. SLIT: Translation to the Practice in the Real World | Dilşad Mungan (Turkey)
 Modifying the Immune Response: Specific Immunotherapy | Mübeccel Akdis (Switzerland)

 POSTER SESSIONS                                                                                                    12.30 – 13.30

16     WISC 2016 6-9 December 2016 Jerusalem, Israel
Preliminary Scientific Program—Thursday, 8 December
SYMPOSIA                                                                                                              13.30 – 15.00
Update on Eosinophilic Gastrointestinal Disease
Epidemiology of EGIDS | Carina Venter (United States)
Pathogenesis of EGIDS | Jonathan Spergel (United States)
Treatment of EGIDS | Ignacio J. Ansotegui (Spain)
Asthma in the Elderly Today
Clinical Features Differentiating Elderly Asthma from Non-Elderly Asthma | Anahi Yañez (Argentina)
Asthma in the Elderly: Role of Comormidities | Arzu Yorgancioglu (Turkey)
What Are the Challengers in Asthma Elderly Treatment? | Sang Heon Cho (Korea)
Desensitization to Drugs & Anaphylaxis
Desensitization to NSAIDS | Pedro Giavina Bianchi (Brazil)
Desensitization to Beta-Lactams | Edgardo Jares (Argentina)
Desensitization to Chemotherapy and Monoclonal Antibodies | Mariana Castells (United States)

WORKSHOP                                                                                                              13:30 – 15.00
Anaphylaxis
Anaphylaxis: Epidemiology and Etiological Factors | Alessandro Fiocchi (Italy)
Food Induced Exercise-Related Anaphylaxis | Stephen Tilles (United States)
The Epipen Device: The Doctor vs. Patient Perspective | Aharon Kessel (Israel)

SISTER SOCIETY SYMPOSIUM                                                                                              13.30 – 15.00
Canadian Society of Allergy and Clinical Immunology (CSACI) - Anaphylaxis, Birth Cohorts,
Development and Eosinophils: The ABC’s of Canadian Allergy Research
Cross Canada Anaphylaxis Registry (CCARE): Lessons in Anaphylaxis from Montreal and Beyond | Ben Shoshan (Canada)
The CHILD study: Lessons from a Birth Cohort | Allan Becker (Canada)
Allergy is in the Blood at Birth: Cord Blood Eosinophil Progenitors Predict the Development of Allergy and Asthma | Judah Denburg (Canada)

COFFEE BREAK                                                                                                          15.00 – 15.30

SYMPOSIA                                                                                                              15.30 – 17.00
Treatment and Management Advances in Ocular Allergy and Other Surface Diseases
Ocular Overview | Paul Greenberger (United States)
Intranasal Steroids and the Eye: Pros and Cons | Leonard Bielory (United States)
Inflammatory Mediators of the Ocular Surface: Implications in Management | Dana Wallace (United States)
Asthma and Poverty: What Can Be Done?
Epidemiology and Clinical Features of Asthma in the Developing World | Alvaro Cruz (Brazil)
Are GINA Guidelines Useful in Underdeveloped Countries | Arnaldo Caprles-Hulett (Venezuela)
Asthma in the Inner Cities of Developed Countries | Wanda Phipatanakul (United States)
Chronic Rhinosinusitis: From Endotypes to Personalized Treatment
Chronic Rhinosinusitis in Children: Relationship to Adenotonsillar Hypertrophy, Sleep Disordered Breathing and Behavioral Disorders: Role
of the Allergist | Bernard Silverman (United States)
Aspirin Sensitivity (AERD) in Chronic Rhinosinusitis (CRS) | Larry Borish (United States)
Personalized Treatment Approaches: Biologics in CRS | Robert Schleimer (United States)
Aberrant Inflammation and Aberrant Immune Programming in Early Life
Immune-Microbiota Interactions in Early Life: Dysbiosis as a Global Health Issue | Susan Prescott (Australia)
The Microbiome and Allergic Disease | Mimi Tang (Australia)
Feeding Modalities: Long-Term Influence on the Immune Responses to Food and Environmental Allergens | Ricardo Sorensen (United States)

JUNIOR MEMBER SYMPOSIUM                                                                                               15.30 – 17.00
What’s Going on in Allergy and Clinical Immunology: Junior Members at the Front Line
Patch Testing Procedures: A Consensus Document | Razvigor Darlenski (Bulgaria)
The Joint Junior Members Survey for Better Formation and Education | Marco Caminati (Italy)
New International Classification of Disease (ICD) and Its Clinical Relevance | Luciana Kase Tanno (France)

                                                                                       WISC 2016 6-9 December 2016 Jerusalem, Israel         17
Preliminary Scientific Program—Friday, 9 December
 KEYNOTE                                                                                                            08.30 – 09.00
 Perturbing Early Life Microbiota Development and Its Immunologic Consequences | Martin J. Blaser (United States)

 PLENARY                                                                                                            09.00 – 10.30
 The Next Frontier for Food Desensitization: Alternatives to Oral Immunotherapy
 Oral Immunotherapy with Adjuvants | Wesley Burks (United States)
 Epicutaneous Desensitization | Hugh Sampson (United States)
 Multiple Food Desensitization | Motohiro Ebisawa (Japan)

 COFFEE BREAK                                                                                                       10.30 – 11.00

 SYMPOSIA                                                                                                           11.00 – 12.30
 Use of Environmental Control to Treat Allergic Disorders
 Taking on Environmental Health History | Wanda Phipatanakul (United States)
 Potentially Fatal Occupational Lung Disease | Chester Zeiss (United States)
 Communicating Findings and Recommending Interventions: What Works? | Adnan Custovic (United Kingdom)
 Severe Asthma in Children
 The Definition of Severe Asthma | Bruce Mazer (Canada)
 Asthma Phenotypes | Leonard Bacharier (United States)
 When Off-Label Medications could be Prescribed | Peter Le Souëf (Australia)
 Phenotypes in Chronic Rhinosinusitis
 Chronic Rhinosinusitis with Nasal Polyps | Robert Schleimer (United States)
 Chronic Rhinosinusitis without Nasal Polyps | Phillippe Gevaert (Belgium)
 Chronic Rhinosinusitis Phenotypes: How to Apply in Clinical Practice | Lou Zhang (China)
 Food Allergy
 Early Intervention of Peanut Allergy | Gideon Lack (United Kingdom)
 Component Resolved Diagnosis in Food Allergy | Motohiro Ebisawa (Japan)
 Microbiome and Food Allergy | David Fleischer (United States)

 JUNIOR MEMBER PRACTICAL COURSE                                                                                     11.00 – 12.30
 Allergy Immunotherapy: What, When and How
 Senior Moderator | TBC
 Junior Member | Orly Ben-Or (Israel)
 Junior Member | Nana Fenny (United States)

18     WISC 2016 6-9 December 2016 Jerusalem, Israel
Registration
REGISTRATION – NOW OPEN!
Register online at www.worldallergy.org/wisc2016/registration

                                                                            Registration Fees - USD
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 Registration Category
                                                        31 July 2016          30 September 2016          9 December 2016
 Delegate                                                  $675.00                  $775.00                   $875.00
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WISC 2016 REGISTRATION INCLUDES:                                SUBSTITUTION POLICY
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and Welcome Reception will receive a reduced registration fee
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                                                                website: www.worldallergy.org/wisc2016/registration.
CANCELLATION AND REFUND POLICY:
• Before/on 31 July 2016: Full refund less $85 USD              VISA POLICY
  administrative fee
                                                                WAO will not be held liable if you are unable to receive
• 01 August – 30 September 2016: 50% refund                     your visa before WISC 2016. Registration refunds will not
• On/after 01 October 2016: No refund                           be provided if you are unable to attend the Conference due
                                                                to not obtaining a visa. Please allow a minimum of 45 days
                                                                to complete the visa application process. For visa questions
                                                                please email: wisc2016@ortra.com.

                                                                             WISC 2016 6-9 December 2016 Jerusalem, Israel      19
Accommodations
 To book your hotel accommodations* for WISC 2016, please visit our website: www.worldallergy.org/wisc2016/
 accommodations
 *The cut-off date for delegates to make hotel reservations online is Friday, 25 November 2016; published rates are subject to
 availability.
 Below is the list of hotels which are being offered at a reduced price for WISC 2016 attendees. All accommodations are being
 handled by WAO’s appointed Professional Conference Organizer – ORTRA, Ltd. – the official PCO for WISC 2016

                                                               Single Rate – USD      Double Rate – USD     Distance to ICC
     Hotels                               Category
                                                               Breakfast included     Breakfast included    Jerusalem
                                          Standard             $163 USD               $179 USD
     Crowne Plaza Jerusalem                                                                                 650 m
                                          Deluxe               $189 USD               $204 USD
     Dan Jerusalem Hotel                  Standard             $143 USD               $164 USD              4.2 km
     Dan Panorama                         Superior             $168 USD               $189 USD
                                                                                                            3.0 km
                                          Deluxe               $197 USD               $217 USD
     David Citadel Hotel
                                          Superior             $311 USD               $332 USD              3.2 km
     Hotel Yehuda                         Standard             $143 ISD               $143 USD              6.9 km
     Inbal Jerusalem Hotel                Superior New City    $235 USD               $250 USD              3.3 km
     Mamilla Hotel                        Studio Room          $291 USD               $311 USD              3.1 km
     Prima Park                           Standard             $128 USD               $140 USD              1.0 km
     Ramada Jerusalem                     Deluxe               $179 UD                $189 USD              950 m
                                          Superior             $357 USD               $377 USD
     Waldorf Astoria Jerusalem                                                                              3.3 km
                                          Deluxe               $367 USD               $388 USD

 CANCELLATION POLICY
 • Cancellations must be requested in writing: wisc2016@ortra.com
 • Cancellation Policy: Refund will be made if written notification of cancellation is received by Ortra Ltd. as follows:
       - Cancellation received until 5 October, 2016 – Full refund less $100 handling fee
       - Cancellation received between 6 October, 2016 – 14 November, 2016 - 50% refund
       - Cancellation received from 15 November, 2016 - No refund
 *Published rates are subject to hotel availability and are not guaranteed. Published rates shall be offered 3 days pre- and post
 official Conference dates (6-9 December 2016) and based on hotel availability only and not guaranteed.
 *Dates are subject to change.

20       WISC 2016 6-9 December 2016 Jerusalem, Israel
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