AVAC 2021 Work Plan - AVAC Engage

 
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AVAC 2021 Work Plan
1. Introduction

AVAC faces, but is also well-prepared for, a significant year ahead. Externally, AVAC confronts an increasingly promising, but also increasingly complex,
HIV prevention research and rollout landscape. From multiple trials in different modalities concluding in the years ahead, to a changing landscape for
prevention trial design, to the prospect of more prevention products competing for attention and funding, AVAC has never been more needed. AVAC has
also expanded its brief and networks to build advocate understanding of and influence over the COVID-19 research enterprise, and to influence planning
and policy-making related to implementation and access for COVID prevention and treatment. At the same time, we are focused on ensuring that
progress in the global AIDS response continues even as significant resources and attention shift to COVID.

Internally, we are responding to the impact of COVID on our own operations, managing the development of a comprehensive 5-year strategic plan,
taking an active role in addressing EDI issues both in the organization’s internal operations and in our alliances with partners, initiating a new Partnership
Network Initiative, welcoming new board leadership and increasing our focus on resource renewal and diversification. This workplan is the product of a
collaborative organization-wide analysis of the opportunities and challenges AVAC will confront in 2021. It reflects our perspective on priority activities
that will make AVAC more focused, more influential and more responsive to the challenges of global environment in the year ahead. With the 2021
landscape in mind, AVAC has refined the organizational goals that will drive and inform our work in the year ahead. They are:

    1. Champion comprehensive HIV prevention and sexual and reproductive health and rights: Advance advocacy around global HIV prevention and
       SRHR through a community and human-centered lens, with a focus on ally-ship to the most affected populations.
    2. Accelerate human-centered R&D, product development and introduction agendas: Guide and pressure developers, funders and policymakers
       to ensure inclusive and comprehensive plans for all relevant populations for products entering and coming out of the research pipeline. Identify,
       raise up, and advocate for reasonable, actionable ways to increase uptake and continuation rates for prevention methods through a people-
       centered lens.
    3. Advocate for equitable funding and access for new prevention options as viable choices: Work with our partners to influence and pressure
       donors, governments, researchers, developers and implementers to ensure that policy, funding, research and delivery efforts are directed to the
       geographies and populations with the most need, with a focus on diverse global and national-level partnerships to accelerate access. Advocate
       for acceleration and equity in the delivery of new methods.
    4. Advance the global movement: Continue to foster and sustain equitable and transparent partnerships with a global cadre of evidence-based,
       impact-driven advocates in the co-creation and advancement of advocacy agendas identified as key priorities by affected populations using
       inclusive, power-sharing models.
    5. Diversify and update AVAC: Diversify AVAC’s staff, senior management, Board, partnerships and funding sources. Increase transparency, equity
       and inclusion in our internal and external operations.

As in past years, AVAC’s workplan presents (2) a work plan summary of each of our program areas and desired outcomes for the year ahead; (3) a
COVID-specific summary; (4) a list of 2021 field-wide milestones that inform and are informed by AVAC’s work; and (5) a list of current major grants. An
inventory of each program’s activities and plans for the year is then included (6) and hopefully makes clear how each team’s activities link to the
advancement of our organization-wide goals.

AVAC 2021 Work Plan                                                           1                                                             December 2020
2. Workplan Summary

              Program Areas                                                              2021 Outcomes/Indicators
 Objective Area 1: Research Engagement:       •    Advocates play an active, independent and leadership role with research entities; are aware of research
 Shape the R&D environment through                 status, issues of concern and investments at the country level and linked to their advocacy work. Civil
 advocacy for investment, political support        society perspectives are reflected in various research agendas.
 and GPP                                      •    Advocates play an active, independent and leadership role in advancing the women's prevention agenda.
                                                   They are aware of the gaps, barriers and issues of concern for women and girls. Civil society perspectives
                                                   are reflected in the women's prevention agenda.
                                              •    Stakeholders recognize and systematically implement GPP as critical to successful clinical research; a
                                                   model for GPP institutionalization is recognized and adapted.
                                              •    Dissemination of R&D information serves the needs of target stakeholders, primarily to ensure their
                                                   contribution to smooth, ethical trial conduct, outcomes and next steps.
                                              •   Inform key external audiences about COVID-19 R&D, and encourage communities to take public-health
                                                  action, promote public awareness, and counter misinformation.
 Objective Area 2: Global Px Movement:        •   Advocacy partners are well-informed and are connected to each other as individuals, organizations and
 Identify, support and connect an informed        coalitions in ways that leverage their collective strengths to advance HIV and COVID-19 prevention
 network of advocacy partners                     implementation and research advocacy.
                                              •   Partners are successful in achieving their advocacy objectives.
                                              •   Partners are able to engage in key events; advocacy network is visible and supports collaborative activity.
                                              •   Networks of communications focal points, journalists, advocates and scientists prepared for,
                                                  communicating about and engaged in accurate information dissemination.
 Objective Area 3: Implementation             •   AVAC and partners’ implementation advocacy secures, via coalition-based work, shifts in policies, service
 Advocacy: Improve evidence-base and              delivery approaches and funding commitments for global HIV, with a particular focus on primary
 rights-based investments in a                    prevention.
 comprehensive response                       •   Implementation advocacy team at AVAC works alongside Africa-based coalition(s) to advance an
                                                  integration agenda for SRHR and HIV prevention that changes awareness among activists of key concepts,
                                                  triggering or reinforcing demands that drive shifts in policy and procurement, with specific attention to
                                                  “multi-layered” prevention and works with Product Introduction to accelerate introduction of the dual pill.
                                              •   Implementation advocacy preserves and expands the financial resources needed for a comprehensive
                                                  response.
                                              •   AVAC’s network and influence help optimize the reach, effectiveness, and/or sustainability of critical
                                                  response activities to COVID-19 in-line with core AVAC principles.

AVAC 2021 Work Plan                                                       2                                                           December 2020
Objective Area 4: Product Intro & Access:   •   Insights on end user preferences and segments result in the development and application of practical tools
 Identify/anticipate needs & gaps and            and interventions.
 provide targeted tools, support & platforms •   Lessons learned and continued research on product introduction are well-documented, disseminated to
 to expand access to px                          inform decision-making, with plans to introduce and scale up available and pipeline products and inform
                                                 COVID-19 response.
                                             •   Donors, advocates, developers and implementers are aligned around comprehensive product
                                                 development and delivery plans.
                                             •   AVAC expertise informs product development and intro for therapeutics, vaccines, or point-of-care
                                                 diagnostics for COVID-19.
 Cross-cutting 5: Program Management &       •   Cross-program coordination mechanisms are defined, deployed, and advance high-priority AVAC-wide
 Coordination                                    strategic initiatives.
                                             •   Internal information-sharing processes are implemented consistently; intellectual property is preserved
                                                 and shared effectively.
                                             •   Staff improve project and time management skills; use of project management tools is consistent and
                                                 formalized across AVAC; similar expectations and practices for “how work gets done” across the
                                                 workstreams.
                                             •   Relationship management practices and norms are set and followed across AVAC.
                                             •   Risk management practices and norms are followed across AVAC.
 Cross-cutting 6: Policy, Data & Analytics   •   Policy advocacy and data analytics contribute to awareness and support for expanded and improved HIV
                                                 prevention research funding and prevention programming.
                                             •   Both HIV and COVID research funding, product development pipelines, and partnership/coalition efforts
                                                 are tracked and provided publicly as tools to ensure awareness and support, as well as to protect critical
                                                 HIV prevention funding.
                                             •   AVAC’s own programs and strategies are informed, developed and improved through robust MEL
                                                 processes.
 Cross-cutting 7: Communications             •   AVAC’s external communications functions and approach adhere to best practices for an advocacy
                                                 organization of this size and scope.
 Cross-cutting 8: Administration             •   AVAC fosters a culture of leadership, accountability, collaboration, and continuous improvement.
                                             •   Human Resources policies, processes, and practices are up-to-date, consistent, and support AVAC’s
                                                 organizational health.
                                             •   All systems are secure, easily accessible, user-friendly, and reliable.
 Cross-cutting 9: Finance                    •   Finance policies and procedures follow current best practices.
                                             •   Staff adhere to policies and procedures; there are no fines, disallowed expenses, and audit findings are
                                                 clean.
                                             •   Sub-grants operations are streamlined and support our programs

AVAC 2021 Work Plan                                                      3                                                          December 2020
3. AVAC 2021 Work Plan – COVID-19 Addendum

As the Covid-19 response evolves, including a likely shift from research to roll-out, there continues to be a strong rationale for AVAC to use its resources,
partnerships, and expertise to influence the global effort to combat the COVID-19 pandemic. While the next 12 months are difficult to forecast, we
anticipate that much of the conversation around Covid-19, and vaccines specifically, will revolve around:

Within this context, AVAC’s unique role to synthesize complex information to develop and implement smart, actionable biomedical prevention advocacy
and product introduction agendas to have meaningful and measurable impact remains both relevant, and urgently needed. AVAC will leverage its
existing expertise and networks to engage in the COVID-19 effort in areas where AVAC’s skills are clearly relevant and will add value. AVAC’s COVID-
specific goals are to:

        •       INFORM key audiences, including advocates, the media, and policymakers with a focus on ensuring our partners are informed on
                intersections between COVID and HIV, including the impact of COVID on HIV research, to strengthen our advocacy
        •       ENGAGE with key audiences, including policymakers, funders, and developers to ensure ethical research conduct in COVID
        •       ADVOCATE for a COVID response that utilizes the lessons, skills, and infrastructure from HIV; protects critical gains in HIV so they are not
                lost; and shapes the global health infrastructure of the future

AVAC 2021 Work Plan                                                           4                                                            December 2020
Org. Objectives/Goals/Covid Sub-goals                                                   COVID-19 Actions
 INFORM key audiences, including advocates, the media, and policymakers on intersections between COVID and HIV, including the impact of COVID on HIV
 research, to strengthen our advocacy
 Research Literacy: Synthesize and communicate complex information      Develop and promote Covid-related resources on AVAC website
 to enhance understanding of COVID-19 research and reinforce the        Develop and sign-on to position statements, commentaries and opinion pieces in-
 importance of science- and data-driven decision-making.                line with AVAC principles
                                                                        Engage in enhanced Social Media campaign around Covid response
                                                                        Develop and participate in timely Covid-related webinars and virtual convening
 ENGAGE with key audiences, including CSOs, policymakers, funders, and developers to ensure ethical and informed conduct of COVID research
 Stakeholders recognize and systematically implement GPP as critical to Develop and deploy relevant GPP Essentials to ensure integration of participatory
 successful clinical research; a model for GPP institutionalization is  practice in Covid R&D
 recognized and adapted for use with COVID-19.                          Engage in GPP advocacy and outreach to enhance GPP uptake w/in Covid R&D effort
 Co-create and convene the Covid Advocates Advisory Board to            Continue to ensure engagement of the CAAB in prioritized Covid research discussions
 support the global COVID-19 research agenda                            Co-create and implement a role for the CAAB related to Covid-19 vaccine access
                                                                        Ongoing participation in CAAB leadership group
 Advocacy partners are well-informed and connected to advance HIV       Provide real-time communications support to AVAC partners
 and COVID-19 prevention implementation and research advocacy in-       Other?
 line with country-specific priorities.
ADVOCATE to demand equity and access to prevention and treatment tools for both COVID and HIV AND ensure that hard-won gains in the HIV/AIDS field
are not lost
                                                                        Develop and promote Access-related resources on AVAC website
                                                                        Engage with emerging multi-stakeholder partnerships and product developers to
                                                                        Identify, apply, and help scale the usage of innovative products, approaches,
 Help drive the discussion around equitable global access to Covid-19   technologies, financing, and platforms for access to vaccines (and other
 vaccines                                                               interventions?);
                                                                        Support the development of risk communication strategies that target and reflect the
                                                                        realities of the most vulnerable populations (using rapid human-centered design
                                                                        approach)
                                                                        Protect HIV programs while facilitating synergies that support COVID research &
 Protecting Global Gains: Continue to drive and grow an advocacy
                                                                        programs
 campaign articulating a post-COVID future of GH in line with AVAC
                                                                        Expand AVAC’s network of influence
 core principles
                                                                        Apply COVID policies in research & programs to HIV

AVAC 2021 Work Plan                                                      5                                                           December 2020
4. Field-wide 2021 Context – a selective list of events, milestones, research highlights, etc., that influence (and/or influenced by) AVAC
programs

 2021 Highlights                                                          J     F     M      A     M      J     J     A      S     O         N   D
 HIV R4P Virtual Conference                                               x     x
 MEL Journal articles (SPARC & COMPASS)                                   x                                                                  x
 COVID-19 Supplement for PEPFAR and GFATM                                 x     x
 PEPFAR COP21 Review Process                                              x     x     x      x
 Global Fund Strategy Development                                         x     x     x      x
 CROI                                                                                 x
 US President’s FY 22 Budget for NIH, PEPFAR and GFATM Released                                    ?      ?     ?      ?
 IAS 2021                                                                                                       x
 International Conf on Family Planning                                                                                                       x
 INTEREST                                                                                                                                        x
 ICASA 2021                                                                                                                                      x
 AMP results                                                              x
 Possible First Approvasl of Dapivirine Ring                                    x     x      x
 Possible FDA Approval of CAB-LA                                                                                                                 x
 Bioequivalence results DPP                                                                                                         x        x   x
 Launch of Islatravir efficacy trials                                                 x      x
 Launch of Lenacapavir and F/TAF efficacy trials                                                   x      x
 USAID RFPs on Microbicides, TBD                                                ?     ?      ?     ?      ?     ?      ?     ?      ?        ?   ?

AVAC 2021 Work Plan                                                   6                                                      December 2020
5. Major Current Grants Table
                                                                                                                           Funds/
                                                                                                                         Obligation
      Current Project          Funder     Timeframe        Amount                  Financial Implications               Received as
                                                                                                                             of
                                                                                                                         12/31/2020       2021           2022           2023            2024        2025       2026
PMM: Prevention Market         BMGF      02/16 - 03/21 $23,891,812    ● Annual grant payment recognized as revenue in   $ 23,891,812
Manager for HIV                                                         year of receipt of payment                                     Discussions underway for renewal from April 2021
Prevention
CASPR: Coalition to            USAID     06/16 - 06/26 $39,991,778    ● Grant agreement has ten-year total with a       $ 17,547,669    3,884,178      4,570,704      4,558,834        4,743,718   4,686,674
Accelerate & Support                                                    ceiling amount which is not guaranteed
Prevention Research
                                                                      ● Annual obligations made by USAID and added
                                                                        to a Line of Credit from which we draw down
                                                                        upon any expense and get reimbursed within 24
                                                                        hours
                                                                      ● Revenue recorded only when reimbursed funds
                                                                        are received
COMPASS Africa: Coalition      BMGF      11/17 - 10/21 $ 6,215,028    ● Annual grant payment recognized as revenue in   $ 8,524,294
to build Momentum,                                     $ 2,309,266      year of receipt of payment                                                   Discussions for renewal from 11/21 pending Learning Assesment
Activism, Solidarity &
Strategy Africa
General operating              BMGF      06/18 - 06/22 $13,200,000    ● Full revenue recorded in 2018                   $ 9,900,000     3,300,000
support to advance                                                    ● Paid annually in June each year
HIV prevention
Development of launch plan      CIFF      08/19 - 1/21 $ 1,235,455    ● Tranche 1: Initial 800k received Sept. 2019     $ 1,235,455    Discussions already underway for renewal from July 2021
for the Dual Protection Pill                          $     500,000   ● Tranche 2: Balance due in July 2020
                                                                      ● Additional bridge funding of $500k Dec 2020
PROMISE: Preparing for      FHI/USAID      6/20 - 5/21 $    225,000   ● Grant agreement has one-year total with a       $   131,250        93,750
Ring Opportunities through                                              ceiling amount which is not guaranteed
Market Introduction Support                                           ● Annual obligations made by FHI 360 only when                   Awaiting USAID RFP for future microbicide funding
and Knowledge Exchange                                                  they receive obligation from USAID
                                                                      ● Revenue recorded only when monthly advance
                                                                        payments are made

                               NEW   10/20 - 10/21 $        250,000   ● Full payment expected prior to end of 2020      $   250,000    Future funding pending initial planning grant
Strengthen/formalize role of
                             VENTURE
the Global AIDS Policy
                               FUND
Partnership (GAPP)

Highlighted section show changes since last report

            AVAC 2021 Work Plan                                                                             7                                                                             December 2020
6. 2021 Consolidated Work Plan

                           Activity                                            Outputs                       Indicators of success          AVAC Goal
 Objective Area 1: Research Engagement: Shape the R&D environment through advocacy for investment, political support and GPP
 Goal 1.1: Enhance both demand and support for HIV biomedical prevention R&D from civil society, communities, policy makers and other key
 stakeholders; support increased financial support for prevention R&D, including through identification of scientific gaps and effective info/data
 sharing
 1.1.1 Monitor the full HIV prevention research pipeline to    Clear articulation of priorities and      A diverse set of advocates      Goal 2:
 identify advocacy interests and opportunities for civil       initial strategies that are rooted in     play an active, independent     Accelerate
 society input on the design and conduct of upcoming trials,   equity and prioritize access to           and leadership role with        human-
 and to prepare for upcoming results                           products for all populations              research entities. They are     centered R&D,
 1.1.1.a Monitor the implications of COVID-19 on the HIV                                                 aware of research status,       product
 research pipeline; map potential COVID-related                                                          issues of concern and           development
 delays/changes; identify engagement strategies to                                                       investments at the country      and
 communicate timeline shifts to stakeholders                                                             level and link them to their    introduction
                                                                                                         advocacy work. Civil society    agendas
 1.1.2 Conduct and/or support research engagement              Effective consultations that increase     perspectives are reflected in
 consultations and follow-up. Due to COVID, this may be        advocate awareness of and                 various research agendas
 through a virtual consultation framework that can be          engagement in key trials; meeting
 shared/adapted by networks, research sites and internal       reports highlighting stakeholder input
 staff. Focus areas may include:                               on key issues and needed actions;
 ● Gilead F/TAF trial                                          literacy and advocacy tools developed
 ● CAB-LA results dissemination and regulatory processes       to meet identified needs
 ● AMP results, bNAb/combo trials
 ● Women’s agenda - MPTs/dap ring approval and post-
      efficacy study/CAB-LA
 ● Dual pill (support Prod Intro)
 ● MTN 034/042/043
 ● Merck Islatravir monthly pill
 ● Ad26 rx program
 ● PrEPVacc
 ● Gilead Lenacapavir (GS-6207), Capsid inhibitor
 ● Merck Islatravir Implant

AVAC 2021 Work Plan                                                       8                                                          December 2020
Activity                                             Outputs                    Indicators of success       AVAC Goal
 1.1.3 Develop and implement research engagement                 Engagement leads to an increased
 mechanisms for specific trials (e.g., F/TAF, combo bNAbs,       prioritization of advocacy
 Merck monthly pill), broader research agendas (e.g., PrEP       interests/concerns by the field;
 for women) or broader issues (e.g., next-gen trial design)      Scoping and defining mechanism(s)
                                                                 may include: call notes/meeting
                                                                 reports; trial design materials for
                                                                 advocates
 1.1.4 Continue work of the Trial Design Academy to stay         Advocates’ perspectives and
 abreast of latest concepts and developments, and to             consolidated priorities for next-gen
 engage with trialists and regulators; consolidate               trials are incorporated into trial
 tools/materials for advocates on Engage; in response to         designs and regulatory decision-
 COVID, facilitate virtual engagements, revise cure fellow       making
 work plans and extend timelines for fellowship; seek
 additional funding for these program/timeline changes as
 appropriate
 1.1.5 Facilitate broad civil society engagement in cure         Meeting report articulating
 research through continuation and expansion of IAS-AVAC         commitments from attendees and
 Cure Academy, possible expanded engagement with cure            concrete ways AVAC and IAS can
 research collaboratories                                        support research translation
 1.1.6 Develop and disseminate HVAD research literacy            Updated HVAD literacy content;
 content; conduct web and social media outreach with             report-backs from community
 partners; support community/ advocacy activities on or          activities
 around HVAD; link messaging to COVID-19 as appropriate,
 highlighting the lessons learned between HIV and COVID
 vaccine development, and to the broader agenda of
 expanding vaccine confidence
 1.1.7 Facilitate advocates’ engagement with regulatory          Regulatory implications mapped
 processes for trials and product approval (e.g., lessons        according to R&D pipeline; advocates’
 learned from DVR, tracking CAB-LA submission, trial design      priorities are articulated and influence
 trainings for regulators (focus on Africa), global regulatory   regulatory decisions/processes
 coordination

AVAC 2021 Work Plan                                                         9                                                       December 2020
Activity                                            Outputs                      Indicators of success         AVAC Goal
 1.1.8 Implement work plan for new strategic partnerships       Scope of work and/or Terms of           A diverse set of advocates      Goal 1:
 focused on the development of women’s health options in        Reference for subgrant(s); final work   play an active, independent     Champion
 Africa; address implications of COVID-19 on women’s health     plans                                   and leadership role in          comprehensive
 and well-being, MPT development and HIV/SRH integration                                                advancing the women's           HIV prevention
                                                                Strategy for SRH strengthening is       prevention agenda. They are     and sexual and
                                                                developed, and coordinated across       aware of the gaps, barriers     reproductive
                                                                CASPR and AVAC more broadly             and issues of concern, such     health and
                                                                                                        as gender equity and            rights
 1.1.9 With CASPR and other partners, build advocacy for a      Ongoing stakeholder engagement          inclusion, for women and
 robust rx agenda for women’s multipurpose prevention,          around SRH integration (with HC-HIV     girls. Civil society
 and to support research for women in all their diversity;      Advocacy WG, cisgender women’s          perspectives are reflected in
 ensure agenda includes gender considerations for COVID-19      group); linked to Engage SRH group      the women's research
                                                                                                        agenda
                                                                HIV px rx pipeline includes
                                                                considerations for pregnant and
                                                                breastfeeding women, dap ring
                                                                approval, lessons from dual pill

                                                                Materials include key advocacy
                                                                messages/statements; literacy
                                                                materials; campaigns
 1.1.10 Conduct a women’s SRH summit, led by African            Advocacy statement; advocacy actions
 women advocates for HIV prevention and SRH advocates,
 focused on addressing gaps in women-centered prevention
 within the R&D pipeline [*in collaboration with Prod Intro];
 make alternate plans for virtual engagement as needed
 1.1.11 Support in-country consultations (Kenya and             Consultation reports
 Zimbabwe) to explore the need, market potential,
 opportunities and anticipated challenges of introducing a
 combined oral contraceptive/ PrEP dual pill [*led by Prod
 Intro; Rx Eng to support]
 Goal 1.2: Enhance GPP globally as a means to efficient, ethical trial conduct and community/civil society readiness for new HIV prevention biomedical
 tools

AVAC 2021 Work Plan                                                       10                                                        December 2020
Activity                                            Outputs                        Indicators of success          AVAC Goal
  1.2.1 Continue GPP training through global online course       GPP training evaluations                  Stakeholders recognize and       Goal 2:
 offerings, adapted online/blended training programs,                                                      systematically implement         Accelerate
 research/institution/trial-specific trainings; and support to                                             GPP as critical to successful    human-
 in-person trainings; implement a TOT program to provide                                                   clinical research; a model for   centered R&D,
 support for additional trainers                                                                           GPP institutionalization is      product
                                                                                                           recognized                       development
 1.2.2 With TB Alliance, Janssen and possibly others, develop    Pilot and dissemination of short course                                    and
 a condensed online GPP training for use at sponsor level;                                                                                  introduction
 consider using as a compliance tool with other GXP                                                                                         agendas
 trainings
 1.2.3 Continue promotion of Engage as a platform for            User satisfaction surveys; metrics
 capacity building and participatory engagement in core          demonstrate utilization of the
 groups (SRH, clinical trial design, CoP and RLNZ) and           platform; new content driven by user
 courses; frame Engage as a strategic platform during            feedback/participation
 COVID-19 to help build interest.
 1.2.4 Consolidate GPP experiences across diseases to            Initial drafts for peer-reviewed
 elevate stakeholder engagement community of practice            publications, case studies and/or tools
 1.2.5 Support partners to develop tools that expand GPP         GPP leadership training curriculum;
 implementation; strategically disseminate C19 Trials            Theory of Change; SETER Course;
 Considerations doc to research groups and advocates,            gender framework analysis; C19 Trials
 support implementation as needed                                Considerations
 Goal 1.3: Develop and maintain strategic research literacy platforms to synthesize, explain and disseminate emerging issues and trial results for a
 broad array of stakeholders
 1.3.1 Develop a series of basic animations that illustrate      At least three videos that can be         Dissemination of basic R&D       Goal 2:
 and build literacy around foundational concepts in HIV          posted on Engage and shared with          information that reflects        Accelerate
 prevention and COVID-19 research and trial designs              trial design academy participants         equity, diversity, inclusion,    human-
                                                                                                           and de-colonized language,       centered R&D,
 1.3.2 With partners, lead research literacy efforts directed    Articles/blogs/podcast; conference        and that serves the needs of     product
 at advocates, journalists and lay audiences around relevant     activity, media cafe report-backs         target stakeholders,             development
 conferences and forums (e.g., HIVR4P CROI, HIV 2021,                                                      primarily to ensure their        and
 ICASA) and focused on key developments and debates in

AVAC 2021 Work Plan                                                        11                                                           December 2020
Activity                                            Outputs                        Indicators of success          AVAC Goal
 the field; identify ways to build literacy and facilitate                                                  contribution to smooth,          introduction
 engagement at virtual conferences Engage                                                                   ethical trial conduct,           agendas
                                                                                                            outcomes and next steps
 1.3.3 Develop additional learning content and tools as           Tools, concepts, pilots
 necessary for activities and programs on Engage, in line
 with user feedback
 Objective Area 2: Global Prevention Movement: Identify, support and connect an informed network of advocacy partners
 Goal 2.1 Through the Fellows Program, support emerging advocates to inform, influence and transform HIV prevention in their communities
 2.1.1. Support 2020 Fellows - through extended Fellowship        Fellows’ project workplans clearly        Moving the dial in key           Goal 4:
 grants - to update and implement strategic projects linked       articulate objectives and activities      processes in tangible ways       Advance the
 to community/country priorities and aligned with AVAC            focused on achievable, strategic wins     related to the Fellows’          global
 objectives. 2020-2021 Project goals include:                     that help advance priority prevention     project goals, including well-   movement
                                                                  goals for their communities and in line   articulated demands; shifts
 ●   Strengthening platforms for SRHR and HIV prevention          with broader CSO coalitions.              in funding; policy changes;
 ●   Working in coalition, in particular with young women,                                                  advocacy
     LGBTI communities, sex workers and with other AVAC           Fellows lead, present and participate     messages/demands
     programs and country coalitions                              in key meetings, events and               articulated by others; place
 ●   Preparing for HIV prevention research milestones             discussions that advance their agendas    at decision-making spaces
     including CAB-LA regulatory processes, AMP study             and priorities of their networks.         that did not exist before or
     results, the start of the Islatravir study and F/TAF trial                                             were limited.
     for women and tracking REACH, Deliver, B-Protected           Final accomplishments will include key
     and ongoing HIV and COVID vaccine and bNAb trials            wins as well as enhanced capacities,
 ●   Increasing access to HIV prevention tools with a focus       skills and understanding and linkages
     on dapivirine ring introduction, dual ring product           of the
     development, regulatory processes for CAB-LA,                coalitions/organizations/networks
     expanded and differentiated access to oral PrEP and          they have engaged.
     treatment in a comprehensive platform
 ●   Leading U=U and Test & Treat campaigns                       Additional outputs include blogs, fact-
 ●   Supporting resource mobilization, with a focus on            sheets, policy briefs, media articles
     PEPFAR 2021, GFATM and increasing domestic                   and other tools that either document
     resources                                                    these efforts, help move the
 ●   Integrating advocacy to demand equity and access to          discussion forward and/or help others
     future prevention and treatment tools for both COVID

AVAC 2021 Work Plan                                                         12                                                           December 2020
Activity                                           Outputs                     Indicators of success          AVAC Goal
     and HIV, specific to community priorities and CS          to support knowledge building in HIV
     campaigns                                                 prevention advocacy.
 Goal 2.2: Launch Fellows 2.0 using inclusive, power-sharing models to ensure it continues to be an important foundational advocacy program for HIV
 prevention
 2.2.1 Define Fellows 2.0 program scope and future plans       Develop alumni, host and stakeholder    Innovative Fellows 2.0          Goal 4:
 based on Impact Evaluation findings and recommendations       working groups                          program builds on strengths     Advance the
                                                                                                       and includes power-sharing      global
                                                                                                       models for peer mentoring,      movement
                                                                                                       support and training.
 2.2.3 Commemorate 10th anniversary of Fellows program         Outputs and products that               Celebration/acknowledgme
                                                               communicate the impact of Fellows       nt of the lessons from the
                                                               program on HIV prevention advocacy,     Fellows Program is shared at
                                                               to include video and social media       selected events with
                                                               campaigns; infographics; and mapping    broader stakeholders.
                                                               Fellows’ impact on the field
 Goal 2.3: Through PxROAR, support peer-to-peer communities of practice for key advocates around community HIV prevention priorities
 2.3.1 EROAR: Support Mosaico community engagement             GPP/community engagement sessions       Local communities of sites      Goal 4:
 with EATG and HVTN, through virtual GPP/community             with Mosaico vaccine sites in Poland,   reached; strong, allied         Advance the
 engagement sessions with vaccine sites.                       Spain and Italy are attended by CABs    support and buy-in of           global
                                                               and local MSM/Trans communities,        vaccine research and            movement
                                                               with the goal of vaccine research       preparedness achieved;
                                                               acceptability and ownership             positive, accurate media
                                                                                                       coverage secured
 2.3.2 EROAR: Influence country-specific milestones for oral   EROAR members are updated,              Advocacy projects
 PrEP access; spotlight regulatory processes for CAB-LA; and   engaged and help influence specific     completed with tangible
 engage /link EROAR partners in COVID research platforms       HIV prevention priority targets         outcomes/ wins such as
 through virtual quarterly RAVES, webinars with key                                                    demand creation and
 researchers and small advocacy grants disbursement                                                    regulatory and funding
                                                                                                       preparedness
 2.3.3 EROAR: In partnership with PrEPster, launch (GPP-HPI)   Broad dissemination and uptake of       GPP SOP for implementation
 Guidelines for HIV Prevention Implementation, to              guidelines/SOP for community            recognized as important

AVAC 2021 Work Plan                                                     13                                                          December 2020
Activity                                          Outputs                      Indicators of success           AVAC Goal
 standardize community engagement in the rollout of new      engagement in rollout of HIV            resource and begins to be
 and existing prevention, as a complement to GPP for         prevention programs and campaigns       adopted by programs
 research
 2.3.4 AROAR: Utilize small grants to strengthen knowledge   Advocacy projects that are context-     Projects produce well-
 building, community engagement and advocacy actions on      specific and conducted in               articulated demands and
 regulatory processes on the CAB-LA dapivirine ring          collaboration with relevant networks    tangible outcomes/wins
                                                             with strategic asks                     such as demand creation,
                                                                                                     regulatory and funding
                                                                                                     preparedness for eventual
                                                                                                     access
 2.3.5 TGRoar: Onboard new TG ROAR team from Research        New TG ROAR team of up to 5             New cadre of TG ROARers
 Agenda project                                              members formed                          continue their work to
                                                                                                     integrate acceptance of
                                                                                                     Agenda in research settings
                                                                                                     and within trans networks
 2.3.6 Support research literacy updates with AROAR,         Research literacy team produces         Literacy updates feed into
 TGROAR members in collaboration with Rx engagement          effective updates on HIV prevention     advocacy plans for LAI, ring,
 team                                                        pipeline                                dual pill and engagement
                                                                                                     around HIV and COVID
                                                                                                     vaccines
 2.3.7 Work with ImpAd on the development of an AVAC-        Consultation with select KPs            Consultations feed into and
 wide KP strategy that consults with AROAR, TGROAR           implemented                             inform overall KP strategy
 members and other AVAC partners engaged on KP                                                       for AVAC
 prevention advocacy work
 2.3.8 US ROAR: Develop US ROAR 2.0, a new strategy for      Zoom RAVE strategy session for 2021     Internal and external
 engagement                                                  planning, with follow-up actions as     agreement on US priorities
                                                             determined through consultation         and how to get there
 2.3. 9 Continuing from 2020 the collaboration with TG       Launch trans-Agenda at R4P or           Commitments from research
 community partners, launch and promote a TGNB-driven        another appropriate venue; execute a    entities and trans networks
 research agenda that achieves the support of trans          promotional strategy for its adoption   to achieve the Agenda
 networks and research entities                                                                      priorities

AVAC 2021 Work Plan                                                    14                                                            December 2020
Activity                                             Outputs                       Indicators of success          AVAC Goal
                                                                 with the Technical Advisory Group and
                                                                 new TG ROARers
 2.3.10: Develop a research literacy training and trial design   A cadre of advocates are prepared to       Trained and fluent ROARers
 engagement, linked with AVAC research literacy team, for        influence outcomes of AMP, Mosaico,        feed into advocacy plans for
 all ROAR teams                                                  dual pill, COVID vax, etc.                 LAI, ring, dual pill
                                                                                                            preparation and community
                                                                                                            engagement around HIV and
                                                                                                            COVID vaccines
 Goal 2.4: Help ensure accurate and supportive media coverage of HIV prevention research and implementation in key African countries, in partnership
 with media partners
 2.4.1 With Internews and media cafe partners, continue to       Trainings, webinars, materials, and        Journalists demonstrate an      Goal 4:
 strengthen the media cafe program to enhance the                connections to key experts in the field    expanded knowledge of           Advance the
 knowledge and skills of key journalists reporting on HIV                                                   R&D, development and            global
 prevention and COVID. 2021 focal points include:                6 cross-cafe collaborations in trainings   introduction agendas, are       movement
 • Implementing the program in partnership with the                                                         up-to-date on key
     conveners;                                                  4 renewed grants country media café        developments in the field
 • Strengthening access to updated information, including        programs                                   and are better equipped to
     AVAC-generated data; and links to AVAC's network of                                                    report on complex and
     advocates, researchers, policy-makers, implementors,        Launch of Malawi café program              nuanced topics in HIV
     representatives of key populations and other experts        Cohesive journalist training program at    prevention
 • Maintaining creative platforms for peer-to-peer sharing,      major conferences.
     including a conveners' gathering
 • Ensuring a gender lens is applied across training and
     cafes.
 2.4.2 Develop and implement cohesive regional journalist        Trainings successfully implemented         Media coverage is more
 trainings linked to milestones/issues in R&D                    around key R&D issues (e.g., ring roll     comprehensive, accurate
                                                                 out, AMP, LAI and COVID and/or linked      and nuanced; AVAC reaches
                                                                 to major conferences e.g., IAS, ICASA,     new journalists and builds
                                                                 Interest, CROI); journalists linked to     greater interest in and
                                                                 AVAC network                               capacity for HIV R&D
                                                                                                            reporting

AVAC 2021 Work Plan                                                        15                                                            December 2020
Activity                                              Outputs                      Indicators of success            AVAC Goal
 2.4.3 Build out South Africa media-engagement network           SA journos have an improved              Media coverage of HIV px
 through work with Internews on community media                  understanding of HIV px landscape in     research, implementation
 program and outreach to top tier SA journos; explore            SA; community media is linked more       and access in South Africa is
 possible partners in SA; consult with relevant research and     effectively to ongoing research          more accurate and nuanced
 implementation partners on needs through Comms WG               projects
 2.4.4 Work with Internews to pilot the "Telling the HIV story   Media cafe conveners are comfortable     Cafes and journos share
 curriculum" journalist training; finalize curriculum and        with and using the curriculum to train   more stories; quality of
 conduct training of trainers program.                           others; curriculum is updated to         stories improves
                                                                 reflect current situation
 2.4.5 Support conveners to develop and implement a new          New awards program developed;            Cafes and journos share
 program to award cafes and individual journalists for best      awards on HIV px and COVID given at      more stories; quality of
 stories on HIV and COVID19 coverage.                            end of year                              stories improves
 2.4.6 Support conveners in documenting cafes, including         Reports, calls, shared info across       Quality of program is
 successes and challenges; work with conveners to share          AVAC; more cafe SPARC stories            improved as lessons learned
 experiences across the program and refine AVAC systems                                                   and best practices are
 for documenting and sharing media cafe activities and                                                    implemented
 other media engagement activities; Incorporate MERL (see
 COMPASS for ex.) into cafe program; output: blogs, joint
 publication (journal), abstracts
 2.4.7 Continue to support HIV prevention communications         Information and messages shared;         Information shared across
 working group to share information, messages and                periodic calls                           the field
 strategies
 Goal 2.5: Expand the pool of informed HIV prevention advocates. Strengthen advocacy capacity of existing and new HIV prevention advocates
 2.5.1 Finalize the Engage ‘Advocacy Navigator’ mentoring        Online mentoring platform up and         Strong interest and                Goal 4:
 program to support civil society and other stakeholders to      running; alumni Fellows mentors are      applications to participate in     Advance the
 develop strategic advocacy plans linked to                      transferring skills to new advocates     the program; strong interest       global
 national/community platforms; train alumni Fellows as                                                    from alumni Fellows in             movement
 online mentors for Phase 1 launch; develop innovative                                                    participating as mentors;
 MERL plan and plans for expansion.                                                                       active co-management of
                                                                                                          content curation by alumni
                                                                                                          Fellows

AVAC 2021 Work Plan                                                        16                                                             December 2020
Activity                                            Outputs                        Indicators of success          AVAC Goal
 2.5.2 Provide ongoing support to existing and emerging         CS engagement on emerging issues          Network of partners makes
 advocate groups and networks interested in HIV prevention                                                clear progress toward
 research advocacy                                              Strategies aligned with partners and      achieving their advocacy
                                                                programs (including AFHNI, national       objectives. Partners are
                                                                px advocacy groups)                       well-informed about trends
                                                                                                          and issues in HIV R&D and
                                                                                                          leverage each other's
                                                                                                          strengths to advance their
                                                                                                          advocacy
 2.5.3 Coordinate advocates’ activities at R4P, including the   Multiple opportunities created to         Advocates feel engaged and
 Advocates Pre-conference and Advocates’ Corner, to             highlight advocacy contribution to HIV    empowered to share their
 support advocates’ visible engagement in the conference;       px research and implementation and        knowledge and experiences;
 promote the Falobi Award as a way to recognize the             ensure advocates’ perspectives are        new and continuing
 contributions of advocates to HIV Prevention Research          highlighted at the conference and in      advocacy alliances are
 Advocacy                                                       media coverage of HIVR4P                  formed; conference
                                                                                                          discussions, debates and
                                                                                                          media coverage consistently
                                                                                                          include advocacy
                                                                                                          perspectives
 Goal 2.6: Advocacy partners are able to link to global efforts to engage, inform and advocate for accelerated introduction of the dapivirine vaginal ring
 through integrated HIV/SRHR platforms
 2.6.1 With CASPR, COMPASS, PMM and advocacy partners,          Advocacy plans are context specific,      Plans produce country- and       Goal 1:
 provide financial and technical support to AVAC CS partners    linked to national priorities and         region-tailored strategies,      Champion
 to develop and implement strategic advocacy plans to           include advocacy to accelerate and/or     including core demands,          comprehensive
 accelerate the introduction of the dapivirine ring.            influence national regulatory             targets and tactics with         HIV prevention
                                                                processes, ring guidelines, policy and    tangible wins.                   and sexual and
                                                                demand creation plans. Plans link                                          reproductive
                                                                advocates to PROMISE partners, IPM                                         health and
                                                                and other relevant implementing                                            rights
                                                                partners and include a small grants
                                                                program, learning symposiums, peer-
                                                                network platform and close

AVAC 2021 Work Plan                                                       17                                                            December 2020
Activity                                         Outputs                        Indicators of success           AVAC Goal
                                                            engagement with other advocacy
                                                            initiatives.
 2.6.2 Foster an enabling media environment for the         Messaging documents shared and            Coordinated and region-
 dapivirine ring through message alignment in the           updated based on user feedback;           specific messaging is
 communications working group, media cafe program and       positioning op eds shared and             incorporated into media
 regional trainings                                         published                                 coverage of the ring,
                                                                                                      influencing public
                                                                                                      perceptions, regulatory
                                                                                                      action and ring interest and
                                                                                                      uptake
 Objective Area 3: Implementation Advocacy: Improve evidence-base and rights-based investments in a comprehensive response
 Goal 3.1: Concrete, actionable primary-prevention and HIV-SRHR-integration “asks,” advocacy and evidence-gathering incorporated into
 transnational coalition work, particularly in East and Southern Africa
 3.1.1 Continue to inform the primary prevention agenda     Community-led monitoring tools that       Key decision makers and           Goal 3:
 advanced by CSOs in the global north and working at        document PrEP, HIV-SRHR, VMMC and         fellow advocates act in           Advocate for
 country-level advocacy                                     differentiated service delivery for ART   response to clearly               equitable
                                                            in Malawi, Tanzania, Uganda and           articulated activist demands      funding and
                                                            Zimbabwe; findings reports that           and positions                     access for new
                                                            remediate problems; replication of                                          prevention
                                                            best practices                                                              options as
                                                                                                                                        viable choices
 3.1.2 Facilitate research to roll out “handoff” for px     Development of a “language-justice”-      Use of “language-justice”         Goal 1:
 products with new approvals and/or pending approvals       derived message/advocacy agenda           derived message/advocacy          Champion
                                                            that encompasses PEPFAR and GFATM         agenda in public-facing           comprehensive
                                                            language on Dap Ring, cis-women’s         documents and forums,             HIV prevention
                                                            perspective on CAB-LA, oral PrEP          including PEPFAR COP              and sexual and
                                                            investments                               guidance and docs                 reproductive
                                                                                                      developed by GAPP and in          health and
                                                                                                      demands to national               rights
                                                                                                      country-level policy makers

AVAC 2021 Work Plan                                                   18                                                             December 2020
Activity                                              Outputs                        Indicators of success            AVAC Goal
 3.1.3 Build activist impact on GFATM programming                  Development and documentation of          Coalition-work yields more         Goal 3:
                                                                   tools, support approaches, tactics that   GFATM data transparency            Advocate for
                                                                   help “hack” the GFATM to gain shifts      and tools that help coalition      equitable
                                                                   in programming, visibility into partner   partners put the data to use       funding and
                                                                   performance and more                                                         access for new
                                                                                                                                                prevention
                                                                                                                                                options as
                                                                                                                                                viable choices
 3.1.4 Support advocacy to maintain essential health               COVID-specific impact assessment          Impact mitigation actions          Goal 3:
 services and mitigate the health, social and economic             tools (developed, compiled in 2020)       taken based on tools               Advocate for
 impact of intersecting pandemics in the three COMPASS             are used/updated in 2021 looking at       assessments; uptake and            equitable
 focus countries                                                   KP, SRHR-HIV, DSD issues; domestic        use of the resource                funding and
                                                                   resource mobilization advocacy pivot      mobilization messaging at          access for new
                                                                   to looking at synergy/risk/positioning    country and global level           prevention
                                                                   of HIV within COVID, pandemic                                                options as
                                                                   preparedness and UHC agendas –                                               viable choices
                                                                   including “transition memo” for
                                                                   potential new US president; AVAC
                                                                   Report 2021 content; tailored tools –
                                                                   webinar, landscape analysis etc. for
                                                                   coalition partners
 3.1.5 Participate, via exchange of technical support and          Increased adoption of policy and          Context-specific campaigns         Goal 4:
 skills, in country-based coalition efforts in Malawi, Tanzania,   program approaches that strengthen        and sets of “asks” (e.g.,          Advance the
 Uganda, Zimbabwe and other priority countries to shift            combination prevention,                   through PEPFAR COP and             global
 barriers to comprehensive HIV responses                           differentiated service delivery and       Global Fund) advanced to           movement
                                                                   other components of a sustainable,        shift barriers
                                                                   comprehensive and integrated HIV
                                                                   response                                  Strengthened advocacy by
                                                                                                             key partners leads to
                                                                   Increased analysis and advocacy           increased identification of
                                                                   capacity among key influencers in         well-framed (evidence-
                                                                   support of HIV and health sector          based) budget and financing
                                                                   financing                                 related barriers (as
                                                                                                             identified in country

AVAC 2021 Work Plan                                                          19                                                              December 2020
Activity                                            Outputs                       Indicators of success           AVAC Goal
                                                                                                         landscapes) addressed over
                                                                                                         reporting cycle
 Goal 3.2: AVAC is a trusted member of a robust, rights-based implementation advocacy coalition that centers PLHIV, people at risk of HIV and civil
 society leaders in the African countries where ImpAd work is centered
 3.2.1 Shift “center of gravity” for ImpAd grant-making -       Development of structured                Pending COMPASS                   Goal 4:
 management and MERL to African partners                        trainings/support to 1-2 COMPASS         extension/funds availability      Advance the
                                                                partners as part of “on-ramp” to         for 2022 – MANET/CEDEP            global
                                                                making and managing subgrants            and/or PZAT begin making          movement
                                                                                                         subgrants within ImpAd
                                                                                                         workplan
 3.2.2 Support civil society globally, regionally and           Coalition in Zambia advances agenda      Zambia KPIF coalition             Goal 4:
 specifically in Kenya, Tanzania, Nigeria and Zambia to         for engagement and program               agenda adopted; activists         Advance the
 engage with Key Population Investment Fund in ways that        structure for KPIF implementation        understand PEPFAR                 global
 result in programs that engage KP-led groups – including as                                             indicators and approaches         movement
 direct funding recipients – and result in positive shifts in   Data for advocacy training               to data presentation and
 service delivery and health outcomes                           implemented for Zambia KP                funding mechanisms and
                                                                Consortium members using peer            begin engagement with
                                                                training model – KP-led groups in        proven strategies for
                                                                Zambia are equipped with skills and      winning shifts in
                                                                knowledge to analyze data and build      implementation
                                                                effective data-driven advocacy           arrangements for KPIF-fund
                                                                campaigns                                programs, leveraging
                                                                                                         additional investments from
                                                                Through peer-led and AVAC facilitated    the government and GFATM
                                                                peer training and mentorship, KP-led     and securing commitments
                                                                groups in Kenya, Nigeria, Tanzania and   from stakeholders to
                                                                Zambia have organizational capacity to   implement approaches
                                                                receive and manage KPIF funds            based on best practices
                                                                directly
                                                                                                         Increased investment in KP
                                                                Cohort of KP expert peer mentors         programming in Zambia in
                                                                engaged to support their CSO peers to    COP 2021

AVAC 2021 Work Plan                                                      20                                                             December 2020
Activity                                             Outputs                       Indicators of success           AVAC Goal
                                                                  strengthen organizational capacity and   KP-led CSOs in Kenya,
                                                                  data-informed advocacy.                  Nigeria, Tanzania and
                                                                                                           Zambia receive KPIF funds
                                                                                                           directly

 3.2.3 Coordinate and support efforts of global and local          KPIF is rolled out with advanced        Global CSOs and In-country        Goal 4:
 CSOs to engage with KPIF Implementing partners, USAID            engagement/collaboration of KP CSOs      CSOs adopt engagement and         Advance the
 and CDC.                                                         in-country, including proposal design,   monitoring plan including         global
                                                                  safety and security plan as well as a    coordinated bi-monthly            movement
                                                                  plan for community-led M/E of KPIF       webinar with IPs and
                                                                                                           USAID/CDC

 3.2.4 Provide technical and financial support to country-        Strengthened coalitions advocating for   Year-Four COMPASS                 Goal 4:
 based teams in Malawi, Tanzania and Zimbabwe and                 data-informed policy and program         coalition “landscape              Advance the
 Northern allies to analyze/document, map landscape               approaches to strengthen a               analyses” and strategic           global
 including actors’ positions, identify barriers, and execute      comprehensive HIV response in            action plans (beginning year      movement
 and evaluate campaigns to shift barriers in favor of a           Malawi, Tanzania and Zimbabwe            4) and CCATS and SPARC
 comprehensive response                                                                                    stories (mid-2021 and end
                                                                                                           2021) reflect clarity on the
                                                                                                           structure of a strong
                                                                                                           campaign, data use and a
                                                                                                           grasp of tactics
 3.2.5 Provide in-country MERL support to country coalitions      1-2 webinars about COMPASS MERL          COMPASS partners take up          Goal 4:
 to reinforce training and practical application of MERL tools,   approaches, learnings and potential      on-demand MERL support            Advance the
 reinforce the importance of MERL for advocacy campaigns          for adaptation                           from PZAT and AVAC and            global
 and respond to specific requests from partners                                                            show improvement in areas         movement
                                                                  Improved documentation of COMPASS        identified for support based
                                                                  campaigns, wins, challenges, lessons     on baseline and post-
                                                                  learned, etc. using C-CAAT and SPARC     support assessment
                                                                  tools
                                                                                                           1-2 Africa-based COMPASS
                                                                  Program management/MERL capacity         partners demonstrate
                                                                  building training for 1-2 partners as    capacity to make and

AVAC 2021 Work Plan                                                         21                                                            December 2020
Activity                                            Outputs                     Indicators of success         AVAC Goal
                                                               on-ramp to Africa based grantmaking      manage COMPASS sub-
                                                               and grant management with robust         grants
                                                               MERL component

 3.2.6 Document successes, challenges, and lessons learned     Website design and launch                Web site designed and          Goal 4:
 from North-South coalition-based advocacy work                                                         launched                       Advance the
                                                               Case studies                                                            global
                                                                                                        3 case studies on COMPASS      movement
                                                               Monthly reports                          partner advocacy campaigns
                                                                                                        written
                                                               Monthly all-COMPASS calls
                                                                                                        12 monthly COMPASS
                                                               MERL reports                             reports developed

                                                                                                        12 monthly COMPASS calls
                                                                                                        conducted and documented
 3.2.7 Submit funding renewal request for COMPASS 2.0          Continued multi-year funding renewal     New grant awarded in 2021
                                                               request for North-South advocacy         from BMGF for continued
                                                               coalition for a comprehensive HIV        COMPASS work
                                                               response with AVAC as prime
 3.2.8 Develop grant manual for COMPASS sub-grantees           Grant manual                             Manual developed

                                                               Improved quality of grant deliverables   Manual rolled out to
                                                               and quicker turnaround time with         COMPASS sub-grantees
                                                               reporting and payments
 3.2.9 Transfer all COMPASS sub-grant related files into the   More intuitive, easy-to-use file         COMPASS sub-grant files
 new filing system on AVAC share drive                         management system                        moved into new system

AVAC 2021 Work Plan                                                      22                                                         December 2020
Activity                                            Outputs                       Indicators of success           AVAC Goal
 3.2.10 Train sub-grantees on AVAC financial and grants         Webinars, zoom trainings                 4 quarterly webinars
 management (e.g., how to complete a finance report)                                                     conducted for groups that
 through webinars/zoom calls                                    Improved quality of grant deliverables   need extra grants
                                                                from sub-grantees                        management support
 3.2.11 Train AVAC COMPASS team on new sub-grants               Sub-grants management software           All AVAC COMPASS
 management software                                            training developed and implemented;      program/grant managers
                                                                AVAC COMPASS grant management            trained in and using new
                                                                team trained and comfortable using       software
                                                                new sub-grants management software

 Objective Area 4: Product Intro & Access: Identify/anticipate needs & gaps and provide targeted tools, support & platforms to expand access to px
 Goal 4.1: Leverage and expand product intro platform to develop comprehensive product intro strategies for multiple products (i.e., ring, CAB-LA, dual
 pill, monthly pill)
 4.1.1 Lead and adapt BioPIC and PMM to coordinate, track       Implement and refine BioPIC product-     Donors, advocates,                Goal 2:
 and monitor investments and introduction of multiple           adaptable framework to improve           developers and                    Accelerate
 products (CAB-LA, ring, dual pill, monthly pill etc.) in the   planning for next-gen products           implementers are aligned          human-
 context of expanding HIV px portfolio                                                                   around comprehensive              centered R&D,
                                                                Adapt governance structure to reflect    product development and           product
                                                                both product-specific and cross-         delivery plans; one               development
                                                                cutting delivery considerations          additional developer              and
                                                                                                         formalizes collaboration          introduction
                                                                Engage community advisory boards         with PMM/BioPIC; new              agendas
                                                                and groups to inform product             biomedical prevention
                                                                adoption decisions, strengthen           products are rolled out in a
                                                                implementation, foster demand            way that supports and
                                                                creation                                 complements the needs of
                                                                                                         communities
 4.1.2 Provide technical and strategic support to IPM, USAID    Strategic plan of action to guide and    Funds mobilized to support
 and PROMISE Consortium for ring introduction and access        coordinate introduction efforts          ring introduction in at
 planning                                                       finalized and implemented                minimum 5 countries

AVAC 2021 Work Plan                                                       23                                                            December 2020
Activity                                           Outputs                        Indicators of success          AVAC Goal
 4.1.3 Lead and coordinate market introduction planning for   Secretariat to Advisory board              Product introduction
 the DPP; refine and articulate a comprehensive market                                                   planned in a coordinated
 introduction strategy for DPP                                Organize regulatory forum to identify      and strategic manner with
                                                              national regulatory pathway and            eased entry to regulatory
                                                              requirements                               approval

                                                              Disseminate market introduction            Donor commitments
                                                              strategy to key donors and                 secured to support further
                                                              stakeholders                               development and
                                                                                                         introduction of the pill and
                                                              Finalize and disseminate investment        to move into the second
                                                              case for dual pill to various donors       phase of the project
 4.1.4 Guide design of and ensure coordination across demo    Key questions identified and               Greater coordination across
 projects for the ring, DPP and CAB-LA                        socialized; sub-study implementing         demo projects; better
                                                              partners understand different              alignment of projects with
                                                              segments and patterns of use across        stakeholder priorities
                                                              different delivery channels
 4.1.5 Strengthen delivery platforms to include integrated,   Promising and proven strategies for        Health systems better
 differentiated and sustainable models to increase access,    integrated HIV px and SRH and              prepared to deliver a wide
 drive uptake and support continued use of the ring, DPP,     simplifying PrEP delivery are              array of HIV Px products
 CAB-LA                                                       documented and implemented

                                                              Continue to support HIV/SRH
                                                              integration policies and service
                                                              delivery in Kenya and Zimbabwe

                                                              Launch new initiatives (i.e., innovation
                                                              challenge) with local partner to design
                                                              and implement innovative strategies
                                                              to strengthen delivery platforms and
                                                              “do PrEP differently”
 4.1.6 COVID-19 Frontline of Access:                          Developments related to COVID access       Civil society input on
 Help drive the discussion around                             curated and synthesized to support         decision-making related to

AVAC 2021 Work Plan                                                     24                                                              December 2020
Activity                                            Outputs                       Indicators of success           AVAC Goal
 equitable global access to COVID vaccines, therapeutics and    partner advocacy; resources              COVID vaccine access and
 diagnostics                                                    developed and disseminated; webinar      distribution is strengthened
                                                                series held to inform advocates

                                                                Specific actions and opportunities for
                                                                advocacy identified in collaboration
                                                                with partners
 Goal 4.2 Amplify proven demand side solutions to inform, influence and improve product development and HIV prevention programs
 4.2.1 Disseminate learnings from pilots in South Africa to     Dissemination meetings held in South     At least 2 implementers           Goal 2:
 inform cost-effective, feasible, scalable and sustainable      Africa and globally                      /partners incorporate             Accelerate
 approaches for more women-centered HIV prevention                                                       learnings into ongoing            human-
 programming                                                                                             programs                          centered R&D,
                                                                                                                                           product
                                                                                                                                           development
                                                                                                                                           and
                                                                                                                                           introduction
                                                                                                                                           agendas
 4.2.2 Build on “user” insights and lessons learned from oral   Analysis of demand generation to         Demand generation
 PrEP and contraception to develop tailored demand              support introduction of ring, CAB-LA     strategies in place and
 generation strategy for the ring, CAB-LA and DPP at national   and DPP developed; messages and          funded for more effective
 and community levels                                           tools tested and refined with women;     product introduction
                                                                costed models for effective demand
                                                                generation created
 4.2.3 Collaborate with developers to act on and incorporate    Updated end-user insights across         New products designed and
 product preferences, attributes and insights in early          populations (especially MSM, FSW in      packaged based on
 product development planning                                   Africa) and contexts mapped as           prevailing preferences of
                                                                resource for donors, implementers        people most likely to use
                                                                and developers; findings from human-     them
                                                                centered design and research shared
                                                                with clinical researchers, NIH and
                                                                product developers

AVAC 2021 Work Plan                                                       25                                                            December 2020
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