COVID-19 UPDATES & PROJECTIONS

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COVID-19 UPDATES & PROJECTIONS
COVID-19
UPDATES & PROJECTIONS
Dr. Salim Sohani, Senior Director, HiE
Dr. Faiza Rab, Doctoral Research fellow, HiE
Christina Angelakis, MPH, Health Officer, HiE
Dr. Donya Razavi, Post-doctoral Research Fellow, HiE
Dr. Mohamed Habsah, Health Advisor, HiE
Sadaf Ekhlas, MPH, Public Health Advisor, IPVOT
Dr. Mekdes Assefa, Volunteer, HiE

May 7 2021
COVID-19 UPDATES & PROJECTIONS
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COVID-19 UPDATES & PROJECTIONS
H1N1 vs. COVID-19 waves: What is different?
                                                               COVID-19 Waves
H1N1 (Spanish Flu) Waves                                       • The first and second waves were not fully flattened as the third
• The second wave was thought to be caused by a more           wave approached
  virulent mutant strain
                                                               • The second wave is merging now into a third wave. The second
• Most deaths occurred with the second wave                    wave caused the greatest number of deaths. It is perpetuated by more
• Those exposed to the first wave and had mild symptoms        virulent variants
  were protected from the following waves                      • Vaccines are likely to protect people against subsequent waves
• Cumulative deaths: 50 million to 100 million, mainly young   • Cumulative deaths so far: 3 million, mainly in the elderly
  adults and pregnant women

                                                                                                                                    3
COVID-19 UPDATES & PROJECTIONS
COVID-19 may become seasonal globally
  Why COVID-19 is likely here to stay               What the Spanish flu tells us
  • History shows that it's nearly impossible to    • In 1918 and 1919, the Spanish flu killed at least 50
    eradicate any infectious disease                  million people around the globe.
  • COVID and influenza vaccines “don't produce     • The virus finally receded mainly because much of
    that sterilizing immunity, which means people     the world's population had already been exposed
    can still get mild infections.                    and developed immunity or died.
  • Vaccine hesitancy and emerging variants         • Although the pandemic ended, the virus never
                                                      really went away. In fact, descendants of the 1918
                                                      flu virus caused deadly outbreaks in 1957, 1968
                                                      and 2009.

In a study published in January 2021, Caetano-Anollés et al., found that COVID-19 cases and
mortality rates are significantly linked to temperature and latitude across 221 countries. This
suggests that once the case numbers start to fall, COVID-19 may become a seasonal illness like the
flu that peaks in the fall and winter.

                                                                                                     4
COVID-19 UPDATES & PROJECTIONS
Intensify
                               • Intensify global vaccination efforts.

                               Monitor
                               • Monitor the epidemic and the emergence of new variants and
If new variants continue         accelerate the modification of vaccines
to appear, winter              Manage and finance
surges may become the          • Manage and finance winter hospital surges.
norm.                          Reduce
                               • Reduce transmission in peak months through employer and
                                 educational institution action.
Five strategies should be      Modify
considered and vigorously
debated in the months ahead.   • Modify behavior of at-risk individuals.

                                                                                              5
COVID-19 UPDATES & PROJECTIONS
Global Updates

  •   Global cumulative numbers 153.2 million infections and 3.2million
      deaths since the start of the pandemic.
  •   Last week →Over 5.7 million new cases reported; 9th consecutive week of
      cases rising; 93,000 new deaths last week; 7th consecutive week of increase.
  •   India accounts for 90% of new cases and death incidences in SE Asia as
      well as 46% of global cases and 25% of global deaths in the last week
  •   India (+20%), ), Brazil (4%), USA (-15%,) Turkey (+32%), and France (-23%)
      reported the highest number of new cases.
  •   Case incidence in the regions of Europe, Eastern Mediterranean, Africa and
      the Americas decreased.
  •   As of May 4th, 2021, a total of 1,047,709,623 vaccine doses have been
      administered.
COVID-19 UPDATES & PROJECTIONS
CANADA- COVID-19
Situation and Hot-spots
COVID-19 UPDATES & PROJECTIONS
3rd May 2021                                19th April 2021

COVID-19 infection rates across
           Canada

                                  Province                          Effective reproduction no. R0   Doubling/halving time (days)

                                  Alberta                       1.1 (0.93 -- 1.3)                   31
                                  British Columbia              0.88 (0.76 -- 1)                    -21
                                  Manitoba                      1.1 (0.84 -- 1.3)                   19
                                  New Brunswick                 1.1 (0.66 -- 1.8)                   23
                                  Newfoundland and Labrador     1.9 (0.51 -- 6)                     3.1
                                  Northwest Territories         1.3 (0.39 -- 2.4)                   9.7
                                  Nova Scotia                   1.2 (0.47 -- 2.2)                   11
                                  Nunavut                       0.62 (0.085 -- 2.2)                 -6.3
                                  Ontario                       0.86 (0.73 -- 1)                    -17
                                  Prince Edward Island          1 (0.41 -- 2)                       140
                                  Quebec                        1.2 (0.92 -- 1.5)                   16
                                  Saskatchewan                  0.94 (0.81 -- 1.1)                  -40
COVID-19 UPDATES & PROJECTIONS
Numbers &
    Change
• In the last 7 days, 53,472 cases were
  reported, down 7% from the previous
  7 days. There were 335 deaths
  announced, down 2% over the same
  period. At least 4,006 people are
  being treated in hospitals and
  1,126,143 others are considered
  recovered.

• About 93% of the 14,835,304 doses
  of vaccine distributed to provinces
  have been administered. That's 36.3
  doses for every 100 people in
  Canada.
COVID-19 UPDATES & PROJECTIONS
Projected Daily Cases and Deaths, Canada
                      Daily infections: We have just passed the peak of a 3 wave.
                                                                              rd

                      The number of daily cases is expected to continue to steadily
                      decline until August. In the worst case-scenario projection,
                      where mobility moves towards pre COVID-19 levels, there
                      could be a dramatic increase of new infections leading to a
                      fourth peak observed in mid to late June.

                        Daily deaths: The modeling shows that we are in the
                        early stages of the 3 wave. In the current projection
                                             rd

                        scenario, where vaccines can be scaled up in 90 days
                        and the UK variant continues to spread in certain
                        locations, a steady increase of daily deaths is
                        expected to peak in late May/ early June, after which it is
                        expected to decline until August
IHME Projections: Alberta, British Columbia,
   Manitoba                 British Columbia
Alberta

                       AB Currently just passed the peak in the number of new cases and beginning
Manitoba               a decreasing trend from which could continue to August.
                       BC currently at the end of a second smaller peak, continuous gradual
                       decrease until August
                       MB Currently on the peak of a third smaller wave, decreasing trend is
                       expecting by mid May and will continue until August.

                       Worst case scenario: AB and BC dramatic increase in cases until early to mid-
                       June MB will experience a slight increase in cases in May followed by an
                       elevated trend until August.
IHME Projections: Ontario, Quebec, N.S, and Saskatchewan
  Saskatchewan                                                         Ontario

     Quebec                                                           Nova Scotia

QC: on the peak of the third wave which is expected to start      N.S on the ascending trajectory of a fourth peak which will reach the peak
descending trend by the mid May through to August.                by mid May and then will start decreasing trend through to August
SK: Just past the peak of the third wave, decreasing trend        ON: just passed the peak of the third wave and will start descending trend
projected through to August                                       through to August
Worst case QC experiences a larger increase in cases peaking      Worst case : ON larger increase in cases reaching the peak early
in June. SK: cases will continue to rise until mid-May and then   June N.S dramatic increase in cases in mid-April through to August
begin a decreasing trajectory
• Covid-19 hospitalizations are increasing in provinces with elevated
                    disease activity
HOSPITALIZATION   • Younger Canadians are ending up in hospital
HIGHLIGHTS FOR    • Risk of ICU admission is 2 x higher and risk of death is 1.5 x higher
THE THIRD WAVE      for the B.1.1.7 variant
                  • COVID-19 threatens health system ability to deal with regular ICU
                    admissions and the ability to care for all patients.
COVID-19, STRUCTURAL RACISM, AND MIGRANT HEALTH

• In Ontario, migrants represent just over 25% of the
  population but 43·5% of COVID-19 cases, mostly
  racialized visible minorities.
• In Toronto, racialized newcomers are over-
  represented in hospital admissions for COVID-19.
• Migrants in British Columbia who are waiting for
  their applications to be processed are, alarmingly,
  slated to be excluded from receipt of public health
  care in early 2021.
•    Ontario's modelling showed three times more
    daily confirmed cases among communities with
    the most essential workers compared with
    communities with the least.

       These crucial gaps in Canada's COVID-19
      response highlight a need to consider and
    intervene in structural racism as a core part of
    the pandemic response and recovery process.
As of May 4th 2021 (11:33am CST) :

                              • 14,205,456 vaccine doses
                                have been administered in
                                Canada
                              • 13,052,548 Canadians have
                                received one dose of vaccine
                              • 1,152,908 have received two
                                doses (are fully vaccinated)
                              • 16,721,432 doses have been
                                delivered to provinces
                                and 85% have been
                                administered
Delivery of vaccines in       • 34.342% of Canadians have
                                received one dose of vaccine
               Canada
VACCINATION
  DISCREPANCIES AND
  CONFUSION IN ONTARIO
Confusion over why certain postal codes met the
criteria for hot spots while other more affected
regions did not is creating mistrust among
residents
• Delays in vaccinating those in some of
    Toronto's hardest hit neighborhoods
• The Auditor General is launching an
    investigation into this matter

Due to vaccine shortages, Scarborough Health
Network and Michael Garron Hospital in East
York were forced to cancel appointments and
close their doors
• This created a panic as many were not
   informed of the cancellation and were
   unable to re-book with at other vaccine clinics
VACCINE SHOPPING
•   The newest phenomenon
•   Tale of two pandemics
      • Affluent residents who can continue working from home are
         shopping around for vaccines until they get vaccinated with
         either Pfizer or Moderna instead of AstraZeneca, often
         booking spots at multiple clinics to ensure they receive the
         vaccine they want
             • More likely to delay getting their first vaccine
             • This is likely to continue occurring as Ontario is now
               allowing those 40 and over to receive AstraZeneca
             • They risk exposing other who have not had the option
               to get vaccinated yet
             • Delay vaccination eligibility from being expanded to
               other groups
      • Racialized residents working minimum wage front-line jobs
         who do not get paid sick days, do not have this luxury and
         are more likely to receive whichever vaccine they can get
Pfizer approvals for adolescents in Canada

• Health Canada has determined that Pfizer vaccine
  is safe and effective at preventing COVID-19 for
  use in children between 12- 15 years of age. [May
  5th 2021]
• However, this approval is contingent and requires
  Pfizer-BioNTech to continue providing
  information to Health Canada on the safety,
  efficacy and quality of the vaccine in this younger
  age group as the vaccine is administered to the
  wider population.
• Following this statement from Health Canada, the
  premier of Alberta, Jason Kenny announced that
  the province plans to begin rollout of the vaccine
  for all people ages 12 and up in the province on
  Monday April 10th
• Over 60% received at least one dose of vaccination in March 2021
Israel   • Since then there is a steady decline in the number of cases now
           reaching baseline for the last couple of weeks
• Very rapid decline in number of cases seen after Jan
USA      • Rapid vaccination
         • Leadership and reinforcement of public health measures
In most countries (Europe and Israel) We saw a drop in number of cases with increase in vaccination
        getting closer to 50% for first dose, this has not been the case in Chile
        Some explanation:
CHILE   • Loosening the COVID-19 public health restrictions too soon as they started rolling out the vaccine
           • Opening lockdowns too soon
           • Permission to travel anywhere with in countries and international travel
        • P1 (Brazilian) variant suggested to be one of the main reason for rapid transmission
        • Type of Vaccine (CoronaVac- Developed in China) 56.5% effective – after two doses. At this point
        12 million [~40%] received one dose and 4 million 2 doses
• 35% of people have received at least one dose of vaccine
Canada   • We can already see the number of cases dropping
GLOBAL VACCINE
TIMELINES

• US and Europe and Israel are
  likely to have 60 to 70% of their
  population fully vaccinated by
  Late 2021
• Canada, Russia, Mexico, South
  Africa, Australia, New Zealand,
  Brazil and few other South
  American countries by mid 2022,
• China, India, Pakistan, Egypt,
  Ethiopia by Late 2022
• The rest of the world which
  mainly consists of LMIC and
  conflict affected areas from 2023
Worldwide Vaccine   • The results of a new poll
Hesitancy             show that vaccine hesitancy
                      worldwide poses a risk to
                      ending the COVID-19
                      pandemic for good.

                    • In 79 out of 117 countries
                      surveyed, the number of
                      people who said they were
                      willing to be vaccinated was
                      below 70%, the minimum
                      percentage of the population
                      that scientists say needs to
                      have immunity to stop the
                      virus from circulating.
Timeline of Variants in Canada

                                   91 cases of new variants          1,515 cases of new
Canada reported its first          (85 of the UK and 9 of            variants (1,408 UK, 108           41,818 cases of VOC             Canada reported its first
case of UK variant                 the South African)                SA, and 3 Brazil)                (39,663 UK, 375 SA,              case of India variant
(Ontario)                          reported in Canada                reported in Canada               1,780 Brazil)                    (Quebec)

                        8 Jan. 2020                      7 Feb. 2021                      16 Mar. 2021                       20 Apr. 2021                     04 May 2021

     26 Dec. 2020                       31 Jan. 2021                     03 Mar. 2021                         13 Apr. 2021                     21 Apr. 2021

                 Canada reported its first         Canada reported its first          3,998 cases of VoC               66,159 cases of VOC               126,450 cases of VOC
                 case of SA variant                case of Brazil variant             (3,777 UK, 238 SA, 71            (63,543 UK, 415 SA, &             (120,835 UK, 735 SA &
                 (Alberta)                         (Toronto)                          Brazil)                          2,201 Brazil)                     4,880 Brazil)
Canada is seeing a mental health
‘crisis’

• A new Ipsos poll suggests 50% of those surveyed
  being deemed at “high risk.”
• Nearly one in 10 Canadians seriously considered
  suicide or self-harm several times over the past
  year, the poll suggests, while 13 per cent
  considered it at least once.
• 53% are willing to discuss their issues with family,
  health professionals or publicly on social media.
DRIVERS FOR MHPSS ACTION – COVID-19 AND BEYOND

Climate change exacerbates risk    Increasing severity of      51 % of adults in 7 countries
 to mental health and wellbeing      disruptive events       perceive COVID affected their MH
          (CCA 2019)                   (WEF, 2019)                     (ICRC, 2020)

   Prevalence of MH issues                                      Pre-COVID, over 1.6 million
doubled in humanitarian crises                                    Canadians with unmet
(IFRC 2019), especially among                                      mental health needs
 most vulnerable/marginalized                                         (CMHA 2019)

  Lack of cohesion, minimal       Neurological and social   Every 40 seconds someone dies by
 coordination in the MHPSS         impact of COVID on           suicide globally (IFRC 2019)
Sector in Canada (Khan 2018)        MH (Lancet 2021)         300% in calls to distress lines (US)
                                                             170% in calls to Kids Help Phone
Situation in India

                     • India continues to record the greatest
                       number of daily COVID-19 cases and
                       fatalities in the world. The country
                       accounts for one in every two infections
                       and one in four deaths recorded
                       worldwide every day.
                     • The average cases in India are six times
                       that of Brazil, which records the second
                       most infections globally and 1.5 times
                       more average deaths than Brazil, which
                       records the second most deaths globally.
                     • India’s test positivity rate is about 21.5%.
                       That is, approximately one in five persons
                       tested are positive (Goa has positivity rate
                       of 48.5% which is the highest.)
• Vaccine cover for people between 18-
                     44 ( total doses given — 11.81 lakh).
                     Overall, 16.50 crores doses
Vaccination          administered so far.
                   • India-All States needs about 24.9
rollout in India     months to administer 150,020,648.00
                     doses (required to vaccinate 75% of its
                     population) at the current rate of
                     2,529,722 doses per day.
Several major Indian cities are
                                                                                          reporting a chronic shortage of
    New variant of concern                                                                hospital beds.

    originating in India
•   As cases surge in India, a new variant strain has been identified as originating in
    the country and has been designated - B.1.617.
•   The new strain has been detected in at least 5 Indian states.
•   6 cases of the B.1.617 variant have been identified in California, cases reported
    in Quebec and BC, Canada, as well as cases identified in the UK, Australia,
    and Singapore.
•   The two separate mutations found in this strain are both characterized by their
    high infectivity and transmission rates.

                             Impact on vaccination
• Scientists believe that the double mutant variant may not have an impact on
  vaccine efficacy
• Initial reports [April 20th 2021] coming from Israeli health officials on suggest
  that Pfizer-BioNTech vaccine is at least partially effective against the new
  variant emerging from India
Projected Daily Cases and Deaths, India
                       Daily infections: India is getting at the peak of its second
                       wave in new daily infection numbers. The incidence of new
                       daily cases is projected to peak in mid to late May after
                       which it will decline until August.

                         Daily deaths: India’s daily deaths is currently at the
                         early stages of the second wave. It is expected to
                         continue to increase until late May. IMHE modeling
                         projects 1,018,879 COVID-19 deaths based on Current
                         projection scenario by August 1, 2021.
RETURN TO WORK -
WHAT THE FUTURE
   MAY HOLD
THE NEW WORLD
OF WORK

• A recent study released by Robert
  Half, a global staffing firm, shows that
  about one in three professionals, or 33
  per cent, currently working from home
  due to the ongoing COVID-19
  pandemic would quit their job to find a
  new one if they were required to return
  to office full-time. A separate poll by
  the recruiter Robert Half showed that
  89% of firms expected some form of
  hybrid working to become permanent
  after the Covid pandemic.
• According to a survey by Boston
  Consulting Group, 53% of workers
  have said they would prefer a hybrid
  model in future.
The future of Canada’s labor
market in a post-COVID world

• Eight megatrends with the potential to impact employment in
  Canada by 2030
• Topics that may at first seem unrelated to Canada’s labor market,
  such as floods, air pollution, and responsible AI, all have the
  potential to impact the future of work.
• To support future-focused planning and avoid blind spots, it is
  important to recognize and understand weaker signals, such as
  wide-scale adoption of cognitive enhancements and the potential
  of another pandemic within the decade, as well as the more
  mature trends like market consolidation and delaying retirement.
2020                          2021                            2022                           2023                           2024
                                   Acute phase                                                     Moving from
     Acute phase                                                                                    transition to              Transformation and
                                continued - moving               Transition phase
   of the Pandemic                                                                              transformation and                  recovery
                               into transition phase                                                  recovery

Declaration of pandemic       Third wave, driven by VOC      Pandemic is likely to start       Sporadic epidemics, the
                              (mutations), may see           receding with pockets of                                        SARC COV-2- Endemic
early in the year                                                                              virus will become endemic
                              decline in cases in summer     Epidemics in different parts
First later a bigger second   and a potential surge or                                         Routine vaccinations          Vaccinations – routine
wave                                                         of the World
                              spike again in Winter                                            against the virus
Health systems:                                              Vaccinations: ongoing                                           Economic boom: as
                              Vaccinations: Roll out         cycles and maybe booster          Socio-economical
Overwhelmed, stretched to     started – uncertain duration                                     vulnerable likely to have     people would start to make
limits and gaps in                                           doses for potential mutations
                              of protection [at least 6      may be required                   increased gap in health       up for the missed social
pandemic preparedness         months]                                                          related inequities. Need      activities
identified                                                   Health systems: More              to refocus on aftermath of
                              VOC- spread of virus           adaptive and organized to         COVID-19- Lung and heart
Health information:                                                                                                          Time to reflect on the
Evolving and messaging        Health systems:                respond to pandemic related       related issues from Long-
                                                             emergencies                                                     response and start better
uncertain                     sporadically becoming                                            COVID                         planning for future
                              overwhelmed                    Mental health issues: More        Continued need for
Natural immunity:                                                                                                            pandemic responses
Uncertainties                 Long term impacts of           likely to be reported after the   supporting Mental Health
                                                             last two years (long term                                       [likely 50 to 100 years]
                              COVID-19 on physical and                                         related issues
Social: Uncertainties,        mental health surfacing        stress related issues)
reluctance/difficulties in                                                                     Economy is likely to have     Health system recovery
adapting to protocols         Lock down fatigue:             Long-COVID, with millions of      a slight boost as people      and building up
                              Physical and mental health     people with respiratory and       slowly return to pre COVID
 Social disparities           impact of lock downs and       fatigue related symptoms.         activities
highlighted                                                                                                                  LMICs will need support in
                              social isolation               COVID also has long term
                                                             impact on heart muscles           Permanent changes in          Health system recovery –
Economic uncertainties:       Economy adapting to                                              workplace situations          pandemic preparedness,
Lockdowns, uncertain          restriction, very slow         Economy: Some                     (with more remote work)
duration                                                                                                                     also refocusing on Pre
                              resurgence                     uncertainty, slow growth.         expected
                                                             Loss of female workforce                                        COVID priorities [SRHR,
Drastic changes in work       Adapting: To public health                                       Health systems:               NCDs] and on aspects that
and social life                                              (large number)
                              measures, new working                                            Recovery phase                suffered as a result of the
Scientific innovation:        realities                      Long term changes in
                                                                                               Important to have             pandemic [drop in global
Vaccines in record time,                                     social and work
                              Socio-economic                 environments as people            continued political will to   vaccination uptake]
innovative approaches to      inequities: increasing gaps                                      ensure public health
delivery of services                                         continue to use protective
                                                             public health advice              readiness for future
                                                                                               pandemics
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