MAYOLY SPINDLER Committed to your health. Every day - 19-INS-319

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MAYOLY SPINDLER Committed to your health. Every day - 19-INS-319
MAYOLY SPINDLER

Committed to your
    health.
   Every day.

                    19-INS-319
MAYOLY SPINDLER Committed to your health. Every day - 19-INS-319
OUR AMBITION
Become an
international
reference
in gastroenterology
and dermo-cosmetics

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MAYOLY SPINDLER Committed to your health. Every day - 19-INS-319
CONTENTS

     OUR ASSETS                  OUR FIELDS OF                     OUR EMPLOYEES’
     A French company             EXPERTISE                         COMMITMENT
 An independent company            Pharmaceuticals                         Our values
An extensive global footprint         Diagnostic                    A responsible company
                                   Dermo-cosmetics
                                Contract Development &
                                    Manufacturing

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                                                         CORPORATE PRESENTATION    08/07/2019
MAYOLY SPINDLER Committed to your health. Every day - 19-INS-319
OUR ASSETS
a French company

▪ Three manufacturing facilities near Paris, 1 in Chatou
  (West of Paris) and 2 in Dammarie-les-Lys (East of Paris).
▪ Over 900 employees worldwide, including nearly 600 in
  France.
▪ Turnover: €182 million in 2018.
▪ 70% of products sold are made in France.
▪ An economic player contributing to France’s status as
  one of the world’s leading pharmaceuticals exporters*.
▪ Exported production : €51 million

 * Source: LEEM (French Pharmaceutical Companies Association)– Economic report, 2016
 issue.

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                                                                 CORPORATE PRESENTATION   08/07/2019
MAYOLY SPINDLER Committed to your health. Every day - 19-INS-319
OUR ASSETS                                                             NET CONSOLIDATED TURNOVER
an independent company                                                      2009-2018 (€ million)

                                                                     200                                                           190
                                                                                                                                             182
                                                                     180                                             167    173
                                                                                                       159    161
                                                                     160
                                                                                                154
                                                                                         145
▪ Founded in 1909: for more than a century, an                       140   126
                                                                                  138

  entrepreneurial adventure.                                         120

                                                                     100

▪ Still an entirely family-owned company.                             80

                                                                      60

▪ Financial independence, a main performance driver.                  40

                                                                      20

                                                                       0
                                                                           2009   2010   2011   2012   2013   2014   2015   2016   2017      2018

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                               CORPORATE PRESENTATION   08/07/2019
MAYOLY SPINDLER Committed to your health. Every day - 19-INS-319
OUR ASSETS
an extensive global footprint

▪ Established worldwide in more than 70 countries
  generating 41% of overall turnover
   ▪ Dynamic subsidiaries: in Europe, Eastern Europe, Asia and
     Latin America (26% of international turnover in 2018)
   ▪ Business partners committed for the long term

▪ A proactive development policy
   ▪ With the acquisition in 2016 of Kibion, a Swedish company
     principally operating in Germany and the Middle East,
                                                                       Subsidiaries
     Mayoly Spindler has become one of the world leaders in the
     detection and control of Helicobacter pylori infections.          Distributors

                                                                                      6
                                 CORPORATE PRESENTATION   08/07/2019
MAYOLY SPINDLER Committed to your health. Every day - 19-INS-319
OUR FIELDS OF
EXPERTISE

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MAYOLY SPINDLER Committed to your health. Every day - 19-INS-319
PHARMACEUTICALS

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MAYOLY SPINDLER Committed to your health. Every day - 19-INS-319
PHARMACEUTICALS                                                  BREAKDOWN OF TURNOVER
Our historical pillar of development                             BY BUSINESS SECTOR IN 2018

▪ Pharmaceutical sector: 72% of overall turnover in                     Diagnostic
                                                                        13 million €
                                                                                                      CDMO*
                                                                                                    12 million €
  2018
▪ Gastroenterology: 80% of our pharmaceutical             Dermo-cosmetics
                                                             26 million €
                                                                                     7%
                                                                                             7%

  business.
                                                                                  13 %
▪ A portfolio of therapeutic solutions spanning
  speciality care, primary care and self-medication.
                                                                                                      72 %
▪ An investment in collaborative R&D in
  gastroenterology.

                                                                                                                  Pharmaceuticals
                                                                                                                    131 million €

                                                            * Contract Development & Manufacturing Organization
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                                                       CORPORATE PRESENTATION                              08/07/2019
MAYOLY SPINDLER Committed to your health. Every day - 19-INS-319
OUR THERAPEUTIC SOLUTIONS PORTFOLIO IN
GASTROENTEROLOGY

           Rx                               OTC
        Biliary lithiasis                    Acid reflux
        Biliary cirrhosis
                                           Travel sickness
      Helicobacter pylori
                                                Gaz
       Abdominal pains
                                       Digestive and renal
        Crohn’s disease                elimination functions

    Pancreatic insufficiency                 Heartburn
        Cystic fibrosis
                                       Probiotics/Gut flora
         Colonoscopy
                                           Constipation

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                               CORPORATE PRESENTATION          08/07/2019
L’ACTIVITE
DIAGNOSTIC
   DIAGNOSTIC

                 PRÉSENTATION À DESTINATION                  11
                                                08/07/2019
                EXCLUSIVE DES INSTITUTIONNELS
DIAGNOSTIC                                                           BREAKDOWN OF TURNOVER
 Our strategic pillar of development                                  BY BUSINESS SECTOR IN 2018

                                                                             Diagnostic
                                                                             13 million €                          CDMO*
                                                                                                                 12 million €

▪ In 2016, Mayoly Spindler acquired Kibion, the world                                   7%
                                                               Dermo-cosmetics                     7%
  leader in fast and reliable urea breath testing machines        26 million €

  and tests for the diagnosis and eradication control of
                                                                                       13 %
  Helicobacter pylori.
▪ In 2019, Mayoly Spindler creates Mayoly Diagnostic, the                                                  72 %
  business unit dedicated to the devlopment of the
  Helicobacter pylori infection diagnosis business.
                                                                                                                       Pharmaceuticals
                                                                                                                         131 million €

                                                                 * Contract Development & Manufacturing Organization
                                                                                                                                  12
                                   CORPORATE PRESENTATION    08/07/2019                                         08/07/2019
DIAGNOSTIC
 Our strategic pillar of development

▪ 95% of duodenal ulcers and 70% of gastric ulcers are
  attributable to Helicobacter pylori’s infection.
▪ Nearly 4 billion people worldwide are infected.

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                                  CORPORATE PRESENTATION   08/07/2019   08/07/2019
DERMO-COSMETICS

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DERMOCOSMETICS                                                           BREAKDOWN OF TURNOVER
     Topicrem, the science of hydration                                       BY BUSINESS SECTOR IN 2018

      ▪ Topicrem: n°1 in body moisturizing milks in                                         Diagnostic
                                                                                            13 million €                         CDMO*

        pharmacies in France since 2013*.                              Dermo-cosmetics
                                                                                                                               12 million €

                                                                          26 million €
      ▪ High-quality manufacturing standards recognized                                                   7%
                                                                                                  7%
        on an international level.
                                                                                        13 %
      ▪ All worldwide production of Topicrem is made in
        France (Dammarie-Les-Lys).
      ▪ An international brand (50% of Topicrem sales                                                              72 %
        generated outside of France).

                                                                                                                                Pharmaceuticals
                                                                                                                                  131 million €
* Source : IQVIA — Pharmatrend PharmaOne (2016-2018) Pharmatrend
NMNM (2013-2016)— marché des hydratants émollients corps femme en
lait/lotion — 2013 a 2018 — en volume.

                                                                         * Contract Development & Manufacturing Organization
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                                                                    CORPORATE PRESENTATION                              08/07/2019
PRODUCTION &
CONTRACT
MANUFACTURING

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PRODUCTION & CONTRACT
MANUFACTURING                                                     BREAKDOWN OF TURNOVER
                                                                  BY BUSINESS SECTOR IN 2018
Technical prowess and responsiveness

                                                                         Diagnostic                                  CDMO*

▪ Three manufacturing facilities near Paris, 1 in
                                                                         13 million €                              12 million €

  Chatou (West of Paris) and 2 in Dammarie-les-Lys (East   Dermo-cosmetics
                                                                                              7%

  of Paris).                                                  26 million €
                                                                                       7%

▪ A softgel capsules expertise requiring a particular                              13 %
  technicality.
▪ A light and reactive structure that adapts to the                                                     72 %
  requirements of our customers.

                                                                                                                     Pharmaceuticals
                                                                                                                       131 million €

                                                             * Contract Development & Manufacturing Organization
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                                                        CORPORATE PRESENTATION                              08/07/2019
PRODUCTION & CONTRACT
MANUFACTURING
Technical prowess and responsiveness

▪ A diversified offer: pharmaceuticals,
  nutraceuticals, dermocosmetics
▪ Various galenic forms: soft capsules, tablets,
  capsules, suppositories, oils, emulsions, gel, micellar
  solutions…

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                                                            CORPORATE PRESENTATION   08/07/2019
OUR EMPLOYEES’
COMMITMENT,
CENTRAL TO OUR
SUCCESS

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OUR VALUES

   RESPONSIBILITY                               RESPECT                                 PRAGMATISM

      Our performance is the result of the talent of our employees who, every day, share ambitious
                                                  projects
                                         and a test for challenge.
      Our corporate culture is reflected in the empowerment of our teams, the opportunity to take
                            initiatives and the pragmatism of each individual.
              Mayoly Spindler is a company where respect goes hand-in-hand with growth,
                                   fostering the well-being of everyone.

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                                                                       CORPORATE PRESENTATION        08/07/2019
A RESPONSIBLE COMPANY

▪ OUR MAYOLY, our corporate responsibility programme.
▪ Three priorities: workplace well-being, commitment to
  the community and care for the environment.
▪ Projects designed and coordinated by employees,
  working in the general interest.

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                               CORPORATE PRESENTATION   08/07/2019
MAYOLY
SPINDLER
AT A GLANCE

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€182 million                           41%
                                       of turnover generated
turnover                               outside of France.
Pharmaceuticals: 72%
Diagnostic : 7%
Dermo-cosmetics: 13%
Production: 7%

Over 900                    3 production sites
employees worldwide,        near Paris: 1 in Chatou
including 600 in France.    and 2 in Dammarie-les-lys

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Figures as at 12/31/2018.
Committed to your
    health.
   Every day.
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