Supporting Biophotonics Companies at all Stages - EPRISE Roadshow Dr. Gerd Illing Oliver Höppner
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EPRISE Roadshow
Supporting Dr. Gerd Illing
Oliver Höppner
Biophotonics
Companies at
all Stages
© 2018
Who we are
Oliver Höppner Gerd Illing
▪ Dipl. Kfm., Business Administration ▪ PhD in Physical Chemistry
(TU Berlin) Marketing/ Controlling/ ▪ Biotech/Medtech consultant with
Corporate Finance focus on biomedical optics for
▪ > 1997 CFO at NOXXON Pharma AG diagnostic and analytical devices
▪ > 2000 VP Finances at GenProfile AG (biophotonics)
▪ > 2002 supporting life science ▪ >10 years experience as CEO (PSF
companies as an interim manager biotech AG, LMTB GmbH)
throughout all commercial and ▪ >20 Jahre years in establishing,
financial affairs. management and evaluation of
▪ experience along the entire large cross-disciplinary R&D
value chain projects
▪ profound network in the areas
financing/investing, science and
industry.
© 2018
Where are the systems /
solutions?
Two Perspectives -
One Message
© 20181st Perspective:
Portfolio Analysis
of ICT-Biophotonics
Projects/Consortia
supported by
© 2018Projects, Programs, Calls, Timelines
COBIOPHAD
LUCA H2020-ICT-2015-28a
INNODERM Some numbers:
RAIS 28 projects
CARDIS
250 partners
INSPECT H2020-ICT-2014-1
SAPHELY 146 M€ total budget
DICOMO 101 M€ EU funding
M3S 97 project years
PHOS-ISTOS
CATACURE
DIAGNOPTICS CIP-ICT-PSP-2013-7 Current state:
Lab2Go
ADVANCE
6 completed
BabyLux 19 ongoing
HEMOSPEC
FP7-ICT-2013-10 3 just starting
BIOPSYSPEN
CAReIOCA
BiophotonicsPlus
VIAMOS
FULLPHASE
FP7-ICT-2011-8
BILOBA
LiPhos
MINERVA
FAMOS
NANO-VISTA FP7-ICT-2011-7
Phast-ID FP7-ICT-2009-5
SPADnet
2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021
© 2018 5Looking for the Medical Need and Coverage (1v2)
BABYLUX: DCS-TRS
Opthalmology FAMOS: OCT, PA Cerebral Bloodflow/Oxyg. Neonatology
CataractCATACURE: Trp-F/Laserbleach
Arterial stiffness
Onc. ThyroidLUCA: DCS-TRS
CARDIS: laser vibrometer
Esophageal Cancer FULLPHASE: PA ImagingCVDs
Melanoma, AK Minerva: NIR LIPHOS: cell spectrosc.signature
DIAGNOPTICS: multimodal
Lab2Go cTn I, IVDAcute Myocard Infarct
INNODERM, RSOM
Staying at the surface:
ADVANCE: OCT
Skin Malignancies Hemospec: Raman, Fl
VIAMOS: OCT Infectious
Non-Melanoma BiopsyPen: OCT Diseases Sepsis RAIS: lf-IVD
Malaria
Keratosis, Psoriasis
PHOSISTOS: PDT Optical Biopsy
Histo/Pathol/Tissue/Cell
CareIOCA: FFOCT M3S: Raman imaging
Cameras SPADnet: PET Inspect: Spectrometers
CLL
for Organs DICOMO: X-ray Head Neck, Larynx
Mouth Cancers
Onc. Biomarker Pancreas
Rheumatoid Arthritis Phast-ID: 2D ph.crystal, lf-IVD
FULLPHASE: PA Imaging
SAPHELY: miRNA-IVD
(Auto)immunology BILOPA: lf-IVD, angiogenesis
Allergies Subcellular imaging
COBIOPHAD:IgE-IVD CompactDisc Research Tools
© 2018 NANO-VISTA: nano-antennaLooking for the Medical Need and Coverage (2v2)
30
25
• Almost all projects aim at diagnostics, only two at with
20
therapeutic solutions only
15
• All are minimal to non-invasive as desired 10
5
• Label free if invasive is still the great challenge!
0
• Missing? Many!
Even some accessible surfaces with great
medical relvance are missing
• PDT 1x,
• Laser surgery/therapy 1x
• Neurology 0x
• Dentistry 0x
• Bronchoscopy 0x
• Gynecology: oncology, reproductive 0x
• Transfusion medicine (blood products),
hematology, renal care…0x
© 2018 7Outcome of 2011 to 2020 ICT Biophotonics Projects
Overall Outcome:
• …
• Shift from components and research tools towards medical systems is clearly visible
over the years and along calls.
• Very successful at component level, less successful at system level
• …
Examples:
• An earlier project claims medical solutions in opthalmology and oncology, will yield
mainly components for OCT.
• Another project claims medical solutions for cancer diagnosis, with some chance to
deliver. They provided already a number of significantly improved components for NIR
applications, some of them world record.
• A later project combines working methods into a multimodal system for skin cancer
diagnosis with strong commitment to clinical validation, multinational approval.
© 2018 82nd Perspective…
…from in between
Companies and Financing
© 2018Our daily
business
© 2018Outcome
□ Great components
□ Not so many great systems / solutions
□ Lack of market focus
□ No systematic analysis of healthcare systems and
players
□ Sticking to the wrong ecosystem:
„research doctors“ instead of practitioners and
patients
© 2018Thank you!
Contact:
illing@h-lsm.de
hoeppner@h-lsm.de
c/o van Aubel & Partner
Kurfürstendamm 57
10707 Berlin
@ Presentation template by SlidesCarnival
© 2018Twenty Years
back:
Start of…
… Infrared and hard X-ray beamlines at BESSY
© 2018Forthcoming ICT Biophotonics Calls
□ ICT-03-2018-2019: Advanced optical medical device
technologies for medical diagnostics (2019 call):
maturing a technology platform and providing access to novel, reliable,
robust optical based devices for in-vivo and/or in-vitro medical diagnosis.
□ ICT-05-2019: Photonics systems for advanced imaging to
support diagnostics driven therapy:
Actions should research ground-breaking, reliable (high sensitivity,
specificity and accuracy), safe to operate, cost-effective and fast
photonics enabled imaging system to support diagnostics during
intervention and treatments of major diseases like cancer
(excluding skin cancer), infectious, degenerative and cardiovascular
diseases.
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