SYNC NEUROMODULATION SYMPOSIUM 2020 NOVEL TREATMENTS FOR THE 21ST CENTURY: THE RISE OF THE BRAIN COMPUTER INTERFACE

Page created by Teresa Sutton
 
CONTINUE READING
SYNC NEUROMODULATION SYMPOSIUM 2020 NOVEL TREATMENTS FOR THE 21ST CENTURY: THE RISE OF THE BRAIN COMPUTER INTERFACE
SyNC Neuromodulation Symposium 2020

   Novel Treatments for the 21st Century:
The Rise of the Brain Computer Interface
    and Neuromodulation of Incontinence

                              Date: 25th November
                     8am-5pm Australian Eastern Daylight Time
                    (afternoon/evening US EST 24th November)

                               Meeting Location:
                  Function Room 277, Sydney Knowledge Hub,
                       Level 2, Merewether Building H04
                              University of Sydney

                  Teleconference attendance via Zoom is encouraged.
             To Register: Go to http://www.joedusseldorp.com/sync-2020
        Please register by 19 November to attend the Sydney venue in person

Hosted by:

Dr Joseph Dusseldorp                           Professor Alistair McEwan
Plastic and Reconstructive Surgeon             Ainsworth Chair of Technology and
Royal Australasian College of Surgeons         Innovation
Concord Clinical School                        Cerebral Palsy Alliance
Faculty of Medicine and Health                 School of Electrical and Information
University of Sydney                           Engineering

                      SyNC Neuromodulation Symposium 2020
SYNC NEUROMODULATION SYMPOSIUM 2020 NOVEL TREATMENTS FOR THE 21ST CENTURY: THE RISE OF THE BRAIN COMPUTER INTERFACE
University of Sydney

                             About the Symposium

The goals of this SyNC symposium are to highlight advances in
neuromodulation, lessons learned and challenges for the future. Researchers
and Clinicians from Australia and internationally will have the opportunity to
interact directly with families in what we hope will be another highly productive
meeting.

                              The Sydney Neurobionics Collaboration was
                               founded in 2018 to address the need for
                           communication between clinicians and biomedical
                                engineers. Our goal is to leverage rapid
                            technological advances to improve outcomes in
                              neuromotor dysfunctions such as spasticity,
                             incontinence and non-verbal communication.

Our last meeting was extremely productive, leading to the initiation of the
Liberty Trial and UnlockCP, an industry collaboration under the MRFF to
explore: Electrical Stimulation of the dorsal columns of the spinal cord with
spinal cord stimulation reduces the reflex hyperactivity and reduces muscle
tone present in spasticity.
Find out more:
The Liberty Trial: https://tinyurl.com/y3d22lon
The Grant: https://tinyurl.com/y43lkyat
The Research Paper: https://tinyurl.com/y3alv7xg

Born out of the University of Sydney, SyNC has developed a broad network of
institutes and entities, including:

 •   The Cerebral Palsy Alliance                   •   Saluda Medical, Sydney
 •   Bionics Queensland                            •   Ingenuity Electronics, Sydney
 •   The ANZAC Research Institute                  •   Cochlear, Sydney
 •   Harvard University, Boston                    •   Synchron Medical, New York
                                                   •   Inventia Life Sciences, Sydney

                        SyNC Neuromodulation Symposium 2020
SYNC NEUROMODULATION SYMPOSIUM 2020 NOVEL TREATMENTS FOR THE 21ST CENTURY: THE RISE OF THE BRAIN COMPUTER INTERFACE
•   Global Surgical Innovations,
    Sydney

We are pleased to welcome another group of clinicians, researchers and
medical technology developers to the 2020 SyNC Neuromodulation
Symposium, including:

                    SyNC Neuromodulation Symposium 2020
Symposium Program
       Note relevant time zones:
       AEDT – Australian Eastern Daylight Time (Sydney)
       QT – Queensland Time
       EST – Eastern Time (USA)

       Session 1:
       Brain Computer Interfaces (BCI): Updates from the Cutting Edge
       Chair: Alistair McEwan, SyNC Founder
       08:00 – 10:10 AEDT (07:00 – 09.10 QT) (16:00 – 18:10 EST)

Time
8:00     Joe Dusseldorp, Alistair McEwan, Convenors     Welcome
8:10     Mariska Vansteensel, Utrecht Brain Centre      Utrecht NeuroProsthesis: Implantable ECoG-based
                                                        BCI for Home Use
8:40     Leigh Hochberg, Brown University               Update on the BrainGate Trial
9:10     Panel Discussion

                                       - Morning Tea: 9:40 – 10:10 -

10:10    Gil Rind, Synchron Medical                     Stentrode: The Australian Deep Brain Interface

       Session 2:
       Living with Communication Challenges in Cerebral Palsy
       Chair: Pete Horsley, Remarkable
       10:40 – 12:00 AEDT (09:40 – 11:00 QT) (18:40 – 20:00 EST)

Time
10:40    Lived Experience and Family Panel Discussion

                                        - Lunch: 12:00 – 13:00 -

                              SyNC Neuromodulation Symposium 2020
Session 3:
    Deep Brain and Spinal Cord Neuromodulation for Movement
    Disorders
    Chair: Joe Dusseldorp, SyNC Founder
    13:00 – 14:40 AEDT (12:00 – 13:40 QT) (21:00 – 23:00 EST)

Time
13:00   David Borton, Brown University               Responsive Neuromodulation of Spinal Cord Injuries
13:20   Hugh McDermott, Bionics Institute            Feedback Control for Deep Brain Stimulation for
                                                     Motor Disorders
13:40   Simon Paget, Children’s Hospital Westmead    The Liberty Trial: Testing Spinal Cord Stimulation for
                                                     Lower Limb Spasticity in Cerebral Palsy
14:00   John Parker, Saluda Medical                  The Unlock CP Project
14:20   Panel Discussion

                                   - Afternoon tea: 14:40 – 15:00 -

    Session 4:
    Sacral Nerve Neuromodulation for Incontinence: Challenges for the
    Future
    Chair: Joe Dusseldorp, SyNC Founder
    15:00 – 17:00 AEDT (14:00 – 16:00 QT) (23:00 – 01:00 EST)

Time
15:00   Pejman Pak                                   Lived Experience Perspective
15:20   Amanda Chung, North Shore Private            Sacral Nerve Neuromodulation for urinary
        Hospital                                     incontinence in adults
15:40   Danielle Delaney, North Shore Private        Sacral Nerve Neuromodulation for urinary
        Hospital                                     incontinence in children
16:00   Margaret Schnitzler, North Shore Private     Sacral Nerve Neuromodulation for Faecal
        Hospital                                     Incontinence
16:20   Gerrit Gmel, Closed Loop Medical             Close Loop Neuromodulation of the Sacral Nerve
16:40   Panel Discussion

                             SyNC Neuromodulation Symposium 2020
Attendance Information

                        Teleconference attendance via Zoom is encouraged.
                    To Register: Go to http://www.joedusseldorp.com/sync-2020

   Please register by 19 November if you are attending the Sydney location in person

                                          Venue logistics

                        Function Room 277, Sydney Knowledge Hub,
                             Level 2, Merewether Building H04
                                    University of Sydney
                   How to find the building: https://cce.sydney.edu.au/site/233

The link below explains parking options at
Sydney University’s Camperdown campus.
Parking is very limited, so it is recommended
that you consider public transport, taxi or Uber.

If you have any difficulty locating the venue,
please contact Dr Dusseldorp on 0411 022 644.
Refreshments and lunch will be provided for
those on site. Wifi will be available at the venue,
with details provided on arrival.

   https://sydney.edu.au/campus-life/getting-to-campus/parking.html

                             SyNC Neuromodulation Symposium 2020
Profiles of Speakers, Chairs and Convenors

Mariska Vansteensel

Mariska Vansteensel obtained her PhD in the field of Neurophysiology in 2006 at Leiden
University Medical Center, the Netherlands. In 2007, she moved to the BCI lab of Nick
Ramsey and she is Assistant Professor at UMC Utrecht. Her main research goal is to use the
wealth of neuroscientific knowledge directly for the benefit of people with disease or
disability. She currently coordinates research on implantable ECoG-based Brain Computer
Interfaces (BCIs) and conducts research within the Utrecht NeuroProsthesis project, which
aims to implement and validate implantable communication-BCIs for home use. In addition,
she is the principal investigator of several projects related to clinical implementation of BCIs
and paediatric neuroscience.
http://neuroprosthesis.eu

Leigh Hochberg

Leigh Hochberg is Professor of Engineering at Brown University and a vascular and critical
care neurologist at Massachusetts General Hospital (MGH), where he also directs the Center
for Neurotechnology and Neurorecovery. His research focuses on the translation of
neurophysiology and computational neuroscience discoveries into devices to restore
function for patients with neurologic disease or injury. As Principal Investigator and lead
Clinical Investigator of the BrainGate Neural Interface team, he is focused on developing and
testing practical, ground-breaking brain-computer interface devices to restore
communication, mobility and independence to people affected by neurologic disease,
paralysis, or limb loss.
https://www.massgeneral.org/neurology/doctors/17357/Leigh-Hochberg
https://www.braingate.org/about-braingate/

Gil Rind

Gil Rind is the Director of Neuromodulation at the pioneering neurotech company, Synchron
Inc., which recently published a first-in-human study demonstrating successful use of the
Stentrode™ brain-computer interface (BCI), or neuroprosthesis. Specifically, the study shows
the Stentrode’s ability to enable patients with severe paralysis to resume daily tasks,
including texting, emailing, shopping and banking online, through direct thought, and
without the need for open brain surgery. The study is the first to demonstrate that a BCI
implanted via the patient’s blood vessels is able to restore the transmission of brain impulses
out of the body, and did so wirelessly. Gil received his Bachelor of Engineering, Mechanical
and Biomedical, from McGill University in 2009. He has been involved in the development of
the Stentrode device for almost 4 years.
https://www.linkedin.com/in/gil-rind-b165603b/

                         SyNC Neuromodulation Symposium 2020
Peter Horsley

Pete Horsley is the founder of Remarkable, a division of Cerebral Palsy Alliance.
Remarkable is a tech accelerator with a mission to harness the power of
technological innovation for driving inclusion of people with disability. Pete has
more than 10 years’ experience in the not for profit sector in youth, corporate
engagement, social impact and innovation, and he is building an ecosystem of
innovators and innovative companies working together to solve the toughest problems in
disability.
https://remarkable.org.au/about-us/

Allan McCay

Allan McCay teaches at the University of Sydney Foundation Program and also at the
University of Sydney Law School, where he is an Adjunct Lecturer. He holds a PhD from the
University of Sydney Law School and is interested in behavioural genetics, neuroscience,
neurotechnology, and the criminal law. He has a particular interest in ethical issues emerging
from artificial intelligence. Allan has co-authored two books: Free Will and the Law: New
Perspectives, published by Routledge, and Neurointerventions and the Law: Regulating
Human Mental Capacity, is published by Oxford University Press. His work can also be found
in many journals and media.
https://www.linkedin.com/in/allan-mccay-81b285185/

David Borton

David Borton is an Assistant Professor of Engineering at Brown University School of
Engineering and the Brown Institute for Brain Science. He is also part of the BrainGate team.
David currently focuses on engineering new tools for wireless neural recording and
stimulation in order to untangle neuromotor disease states, and more generally to
understand how these states are dynamically represented in the brain and spinal cord. Using
these tools, he explores how motor processing in the brain evolves during long-term,
naturalistic recording. David received his Bachelors degree in Biomedical Engineering from
Washington University in St. Louis in 2006, his doctorate in Biomedical Engineering from
Brown University in 2012, and performed his post-doctoral training at the Ecole
Polytechnique in Lausanne Switzerland (EPFL) under a Marie Curie International Fellowship.
In 2015, Prof. Borton received the DARPA Young Faculty Award.
https://www.braingate.org/team/david-borton-ph-d/

                        SyNC Neuromodulation Symposium 2020
Hugh McDermott

Professor Hugh McDermott is the Chief Technology Officer of the Bionics Institute and Chief
Science Officer of a start-up company, Deep Brain Stimulation Technologies Pty Ltd. He also
holds honorary appointments as a Professorial Fellow at The University of Melbourne. Hugh
is an inventor on over 25 patent families. Several of his inventions have been successfully
implemented in commercial products available worldwide. Hugh has contributed to the
design, development, and evaluation of neurostimulation devices, particularly cochlear
implants and biomedical signal-processing systems, for over 35 years. In the past 10 years
his work has extended into the fields of prosthetic vision and brain stimulation. The latter
research aims to treat conditions such as movement disorders, including Parkinson’s disease,
by electric stimulation of selected brain targets.
https://www.bionicsinstitute.org/FAQs/prof-hugh-mcdermott

Simon Paget

Simon Paget is a Paediatric Rehabilitation Medicine Physician and the Head of the Cerebral
Palsy and Movement Disorders Service at Kids Rehab, the Children's Hospital at Westmead.
He is passionate about improving healthcare delivery through clinical innovation and
research, and leads a team dedicated to improving outcomes for children with cerebral palsy
and their families.
https://www.linkedin.com/in/simon-paget-16618270/

John Parker

John Parker is the founder and CEO of Saluda Medical. The company is commercialising
research from Australia's Information Communications Technology Centre of Excellence
(NICTA). John founded the Implant Systems team at NICTA that developed the closed loop
feedback technology. He has over 20 years of experience in medical devices, including 13
years at Cochlear Limited, where he served in the role of Chief Technology Officer and
Executive Member of the Board of Directors.
https://www.afr.com/brand/boss/true-leaders-game-changers-2017-john-parker-saluda-
medical-20170919-gykkaj

Amanda Chung

Amanda Chung completed her medical degree at the University of New South Wales in
2007, Master of Surgery (MS) at the University of Sydney in 2012, and a Fellowship of the
Society of Genitourinary Reconstructive Surgeons (Eastern Virginia Medical School, Norfolk
VA, USA) in 2017. She combines her clinical work with research and is currently undertaking a
PhD through the University of Sydney. Her research topic is “Detrusor ultrastructural studies
in geriatric lower urinary tract dysfunction: correlation of features and development of a
standardised protocol. Dr Amanda Chung joined Sydney Urological Associates in 2018 and
operates at a number of Sydney hospitals.
https://urologist.net.au/profile/dr-amanda-chung-2/

                        SyNC Neuromodulation Symposium 2020
Danielle Delaney

Danielle Delaney completed her medical training at the University of Sydney and the
Northern Clinical School (Royal North Shore Hospital) and her formal Urology training in
Victoria. She has since opened a private practice offering services to both adults and
children. Danielle has a special interest in functional urology and is passionate about
optimising bladder function from birth to death. At Sydney Children’s Hospital, Randwick,
she has improved management of continence issues for children and adolescents. She has
been involved in two international clinical trials for Overactive Bladder (OAB) in adolescents
and neurogenic bladder in children and adolescents. Danielle often works as a proctor
instructing urological colleagues on subspecialised procedures such as sacral
neuromodulation for urinary incontinence.
https://www.drdanielledelaney.com.au

Margaret Schnitzler

Associate Professor Margaret Schnitzler is a specialist colorectal surgeon. She trained
in surgery at Royal North Shore Hospital and obtained further specialist training in
colorectal surgery at the Ferguson Clinic in Michigan, USA and the University of
Toronto, Canada. She completed her PhD on molecular genetics of colorectal cancer
at the University of Sydney Her main clinical interests are in familial colorectal cancer,
anorectal conditions, faecal incontinence and pelvic floor disorders. A/Prof Schnitzler
has a teaching appointment at the University of Sydney and is Sub-Dean for Surgery
and Academic Coordinator for Surgery at the Northern Clinical School, University of
Sydney.
https://northernsydneycolorectal.com.au/our-doctors/dr-margaret-schnitzler

Gerrit Gmel

Gerrit Gmel is the Project Leader at Closed Loop Medical. Completing a PhD in 2016 with a
crossover project between engineering and neuroscience, Gerrit applied his deep passion
for unravelling the mechanisms of action of neuromodulation to a wide range of applications
including spinal cord stimulation, sacral nerve stimulation, and deep brain stimulation. He
manages the clinical research efforts at Closed Loop Medical, running basic science
experiments, first-in-human trials, and larger safety and performance studies. He is interested
in all aspects of neuromodulation, from the basic neuroscience to product development to
the commercial aspects of bringing new products to market.
https://www.linkedin.com/in/gerrit-gmel-phd-15a93149/

                        SyNC Neuromodulation Symposium 2020
Symposium Convenors

Joe Dusseldorp

Joe Dusseldorp is a Plastic and Reconstructive surgeon with a special focus on
cutting-edge facial reconstructive and facial nerve reanimation surgery. His research
is focused on solving some of the difficult problems in plastic surgery, particularly,
malformations of the ear, facial palsy, cerebral palsy, and peripheral neuropathy in
diabetic feet. Among other roles, he is currently the Co-ordinating Principal
Investigator with Saluda Medical for the Liberty Trial, a world-first clinical trial
seeking to find an “outside-the-box” solution for the physical disability affecting
children with cerebral palsy. He is a Clinical Senior Lecturer at University of Sydney,
co-founder of the Sydney Neurobionics Collaboration (SyNC), and he provides
reconstructive plastic surgery services from his own practice and at numerous Sydney
hospitals.
https://www.joedusseldorp.com/about-dr-joe-dusseldorp

Alistair McEwan

Alistair McEwan is currently Ainsworth Chair of Technology and Innovation within the Sydney
University School of Electrical and Information Engineering, conducting research into
bioelectronics, the electrical and optical properties of tissue, and disabilities such as cerebral
palsy. His research focuses on using signal processing, electronics and modelling to
understand the effects of the impedance of tissue as a biomarker in neurology, cardiology,
musculoskeletal tissue and the effect on neuromodulation, and he works closely with
clinicians from a number of Sydney hospitals. He is co-founder of the Sydney
Neurobionics Collaboration (SyNC).
https://sydney.edu.au/engineering/people/alistair.mcewan.php

                                             Notes

                         SyNC Neuromodulation Symposium 2020
You can also read