The 2020/1 Blended Learning Journey on Metastatic Renal Cell Carcinoma (mRCC) LIVE WEBINAR for APAC - Saturday, 24 April 2021

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The 2020/1 Blended Learning Journey on Metastatic Renal Cell Carcinoma (mRCC) LIVE WEBINAR for APAC - Saturday, 24 April 2021
The 2020/1
Blended Learning Journey
on Metastatic Renal
Cell Carcinoma (mRCC)
LIVE WEBINAR for APAC

              Saturday,
              24 April 2021
              from 11:00 to 12:00 CEST
The 2020/1 Blended Learning Journey on Metastatic Renal Cell Carcinoma (mRCC) LIVE WEBINAR for APAC - Saturday, 24 April 2021
OVERVIEW
Renal Cell Carcinoma (RCC) is a common tumor of the elderly, which has consistently
increased in incidence over the past decade. While operative techniques have
advanced in recent years and now offer renal preservation and minimal operative
trauma where possible, adjuvant measures are not established. Medical treatment
remains mostly confined to those with relapsed or metastatic disease, when local
therapies are not suitable. The first wave of medical treatments for RCC consisted of
cytokines, which had some impact on patient prognosis (overall survival increased
to a median of 13 months), but clearly lacked efficacy. Unraveling the molecular
carcinogenesis of clear cell RCC spurred the development of targeted therapies,
tyrosine kinase inhibitors (TKI), which inhibit the tumor vasculature and have
noticeably improved the efficacy of RCC medical treatment. More recently, check
point inhibitors (CPI) have entered the therapeutic arena - the latest milestone of
clinical development. These tools allow further optimization of treatment by permitting
combinations of different therapies. Today, first-line therapies are composed of CPI-
based combinations, which have shifted median overall survival expectation to >40
months. This live webinar brings together a panel of international experts, who will
discuss the rapid development of medical treatments with a particular focus on
contemporary medical treatment in advanced or metastatic RCC.

LEARNING OBJECTIVES
By attending this live educational webinar learners will be able to:
• Diagnose RCC and categorize the disease into stages
• Use the stages of disease to help inform therapy decisions
• Know the latest guideline recommendations for patients with RCC
• Understand the science/trials behind the latest guideline updates
• Be more confident about prescribing choices for patients at all stages of RCC

TARGET AUDIENCE
This webinar is designed for Oncologists, Urologists and specialists from the APAC
Region, involved in the diagnosis and management of patients with metastatic renal
cell carcinoma (mRCC).

LANGUAGE
The official language of this live educational webinar is English.
Simultaneous translation into Japanese will be provided.

CME ACCREDITATION
The 2020/1 Blended Learning Journey on Metastatic Renal Cell
Carcinoma (mRCC) - LIVE WEBINAR for APAC, 24/04/2021 - 24/04/2021
has been submitted for CME accreditation to the European Accreditation Council for
Continuing Medical Education (EACCME®).

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CME PROVIDER
Scientific Seminars International Foundation
CME Manager: Flaminia Masprone
T +39 380 1504116 - F +39 06 4827169
info@scientificseminars.com

PRE-REGISTRATION AND SURVEY
To access the live webinar, please register by clicking on the below link:
https://www.elearning.scientificseminars.com/the-2020-21-blended-
learning-journey-on-metastatic-renal-cell-carcinoma-mrcc/live-webinar-
for-apac/
and complete a very short survey covering your current knowledge of the subject
matter prior to attending the webinar.

                                                                             3
FACULTY

Viktor Grünwald                       Jens Bedke
Professor for interdisciplinary       Department of Urology
genitourinary oncology                Eberhard Karls University Tübingen
University Hospital Essen (AöR)       Tübingen, Germany
West-German Cancer Center Essen
Clinic for Medical Oncology and
Clinic for Urology
Essen, Germany

Eto Masatoshi
Professor and Chairman
Department of Urology
Graduate School of Medical Sciences
Kyushu University
Fukuoka, Japan
                                                                           4
SATURDAY, 24 APRIL 2021
from 11:00 to 12:00 CEST

11:00		 Welcome and introduction
		      V. Grünwald (Germany)

11:05 L1         Background and drug development in mRCC
		               V. Grünwald (Germany)

11:15 L2         Current clinical data
		               Eto Masatoshi (Japan)
                 Abstract: The rapidly evolving treatment landscape of mRCC has led to the
                 latest development of check point inhibitor (CPI)-based drug combinations
                 in first line treatment. Although these combinations offer broad clinical
                 activity and their use is associated with a median overall survival >40
                 months, the next generation of CPI-based combinations appeared. These
                 later combinations combine CPIs with 3rd generation tyrosine kinase
                 inhibitors (TKI) to broaden the clinical activity. We will discuss the latest data
                 and their implication for the treatment landscape in mRCC. In details:
                 • Javelin-101 renal
                 • KN-426
                 • Checkmate 214
                 • Cheeckmate 9ER
                 • CLEAR

11:30     L3     Clinical case - Individualizing therapy for a treatment naïve
                 patient just diagnosed with mRCC: treatment options, and their
                 progress on therapy
		               J. Bedke (Germany)
                 Abstract: We will present a case scenario of a patient with mRCC, who
                 is rendered treatment-naïve. The interpretation of clinical data will be
                 discussed, waying pros and cons of different treatment options in order to
                 individualize therapeutic choices.

11:45     P      Panel discussion

11:55		          Summary and closing remarks
		               V. Grünwald (Germany)

12.00		          End of the live webinar

LEGEND                                                                                           5
L: Lecture; P: Panel discussion
All Scientific Seminars International Foundation programs are organized solely to promote the
exchange and dissemination of scientific and medical information. No forms of promotional
activities are permitted. There may be presentations discussing investigational uses of various
products. These views are the responsibility of the named speakers, and do not represent an
endorsement or recommendation on the part of Scientific Seminars International Foundation.
This independent educational program is made possible thanks to an educational grant
received from Merck Healthcare KGaA Darmstadt, Germany.

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Copyright © Scientific Seminars International Foundation, 2021. All rights reserved.
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