Trust is good, control is better? - Current HighTech Scientifically illuminated and tested for effectiveness

Trust is good, control is better?
Current HighTech
Scientifically illuminated and tested for effectiveness

Uwe Paasch
University Hospital Laipzig AöR
Clinic for Dermatology, Venereology and Allergology
Conference Dermatological Practice Frankenthal on March 3rd, 2012

Terms

  Jet
        - Jet
        - Liquid jet
  Stream
        - Beam
        - River
        - Flow
  Jetstream
        - Jetstream
  JetPeel
        - Originally used in surgery
        - Translation in aesthetics
        - Exploration for dermatology

Substances

Working principle

Potential areas of application
 Hydropressure
    - Massage
    - Lymphatic drainage
        • Rosacea
 Hydroabrasion
    - Exfoliation / Wound cleaning
    - purification
    - comedolysis
        • Acne
 Hydroporation
    - Hyaluronic acid
    - Vitamins A, C, B5
    - Glycolic acid
    - Triamcinolone
    - Local anesthetics
    - Macromolecules

Systems

Skin thick and sensitive Areas on the face

                               Fig. 3.1 Certain areas of the face react more sensitively than others
                               to the Laserenegrie, which should be adjusted accordingly. These
                               are in particular thin areas of skin or those with bony, cartilaginous
                               structures or teeth lying close below.

Pilot study
  Pilot study on the Safety, Efficiency and potential uses of
  Hydroabrasion and fractional Hydroporation in Dermatology.
       - Read out and Development Parameters
            • Subjective Assessments by Patient and Doctor
            • Digital Photography
            • 3D Photography
            • Incident light microscopy with 30x magnification and polarization
            • Histology on the porcine and human Explant
            • Development of a Training concept
       - Evaluation of the Hydromassage and lymphatic drainage clinic
       - Evaluation of the clinic of Hydrocomedosis and Hydroabrasive Acne therapy
       - Evaluation of the penetration depth of fractional Hydroporation of liquid,
         viscous and crystalline Substances

3D Photography

3D Photography

Hydroporation Clinic - "massage / lymph drainage"

Histology Massage

Technique of Lymphatic drainage

Technique of Lymphatic drainage

Technique of Lymphatic drainage

5-10 cm distance from skin
90 ° to the skin surface
Continuous movement
Protection of the orificii oculi, nasi et auriculae, eyelids and lips
First the left half of the face, then the right side

Evaluation of hydrocomedolysis and hydroabrasive acne therapy

Procedure

Hydroabrasion and - injection at 1cm distance from the Skin

Hydrocomedectomy - Limits

Applicator for Vacuum

Clinic reflected light microscopy

Klink 3D Photography

Formation of dermal cavities when the epidermis is intact

The targeted application of vitamin A on an area of a few cm2 over 10s leads to
      • Focal horizontal removal of the episermis
      • Introduction of small to medium volumes between the fibers with "springiness" compared to the control
      • Application of very large volumes in sections in depth

The targeted application of vitamin C over an area of a few cm2
over 30s leads to:

     • Focal horizontal removal of the epidermis
     • Introduction of small to medium volumes
       between the fibers with "springing"

Hydroabrasion and injection technique

Pneumoporation of low viscosity substances

The targeted application of non-crosslinked hyaluronic acid on an area of a few cm2 over 30s leads to:
     • Focal horizontal ablation of the epidermis and deposition of HA
     • Insertion of small to medium volumes between the fibers with "springing up", application of
       large volumes in sections in depth

Pneumoporation with native Hyaluronic acid high flow

 Focal Epidermis ablated
 Dermal deposits up to approx. 1 mm deep in fatty tissue

Pneumoporation with native hyaluronic acid 30s decreased flow

The targeted application of Hyaluronic acid on an area of a few cm2 over 30s with reduced flow leads to:
     • Focal horizontal removal of the epidermis and deposition of HA
     • Introduction of small to medium volumes between the fibers with "springing"
     • Application of large volimina in sections in depth

Comparison of classic injection of low-crosslinked hyaluronic acid

Pneumoporation with native Hyaluronic acid

Pneumoporation with native Hyaluronic acid

Pneumoporation of Highly viscous substances

Pneumoporation of Highly viscous substances

Pneumoporation of Crystalloid substances

 Pneumoporation of crystalloid substances (triamcinolone) is possible continuously without constipation
 Penetration up to approx. 2.5 mm into normal connective tissue can be detected
 Reduced penetration into scar tissue
 Only marginal penetraion in keloids

Outlook

 Potential for use in Dermatology
    - Rosacea
         • Mb. Morbihan
    - Acne
    - Aesthetics
         • Wrinkles, PIH, texture, pores
         • Striae
         • Alopecia
    - Scar
    - Targeted disease control
         • WSC Hedhog Inhibitors
         • PDT
         • Local antibody, capsosome, polydextrin or PEG deposition

 Potential combinations
    - Lasers absorbing water in the water
    - RF