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2021
II Bio.Natural-Bioactive Natural
Products Research Meeting
November 18-19, 2021 | Virtual
Time zone: Portugal Time (GMT)
Write us at: organizer@bionaturalconference.com | www.bionaturalconference.com
BIO-NATURAL-2021, NOVEMBER 18-19, 2021 | VIRTUAL
About The Conference
United Scientific Group in collaboration with CBIOS, the Research Center for Biosciences & Health
Technologies at Universidade Lusófona proud to announce and warmly welcome you to the second
edition of virtual conference on II Bio.Natural 2021 – Bioactive Natural Products Research, going to
happen on November 18-19, 2021. The conference will offer a unique opportunity to share the latest
updates, cutting-edge technological tools, and scientific advances in Natural Products research.
It will be a stupendous platform to present the latest advances in Natural Products research and to
provoke new collaborations and exchange information on cutting-edge information on research &
drug discovery.
Reasons to Attend II Bio.Naturals-2021
Learn
II Bio.Natural 2021 is unique in its approach of encouraging a dialogue between speakers
and delegates through its well-planned agenda with the series of talks, poster presentations,
panel discussions and networking events that will keep participants engaged in learning.
Discover
The conference aims to provide timely, evidence-based information that helps allied experts
from academic institutions, government agencies, societies, non-profit organizations and the
industry towards natural products research and development.
Connect
II Bio.Natural 2021 connects life sciences and biomedical researchers from all over the
globe to network and share cutting-edge research that leads to new break-throughs and
career advancement. This meeting is focused to deliver top notch scientific lectures in the
fields of natural products and drug discovery.
Previous Edition
I Bio.Natural virtual conference was held on 27-28 September 2019, and it was a great
success! The conference has brought together speakers from leading institutes and
organizations having a diverse subject expertise to deliver intensive and thought–provoking
presentations.
Scientific Sessions
The conference is focused to deliver top notch scientific lectures in the fields discovery of natural
products, natural products drug discovery, chemistry of natural products, marine natural products,
functional foods. The subject areas may include, but are not limited to the following domains:
1. Natural Products in Drug Discovery 5. Natural Cosmetics
2. Natural Products Chemistry 6. Functional foods and food supplements
3. Bioactivity of Natural Products 7. Other fields related to Natural Products
4. Marine Natural Products
BIO-NATURAL-2021, NOVEMBER 18-19, 2021 | VIRTUAL
Our Partners:
Lusófona University of Humanities and Technologies
is the largest Portuguese private university, and the main
institution of Grupo Lusófona, which administers other
universities and colleges in Portugal, Brazil, Cape Verde,
Angola, Guinea-Bissau and Mozambique.
CBIOS, the Research Center for Biosciences & Health
Technologies was created in 2011 as a R&D structure of
COFAC / Universidade Lusófona to create and promote
knowledge in the health sciences. As part of our vision,
CBIOS develops Integrated Health Strategies aimed to
support the progress of Lusophone societies.
United Scientific Group (USG) is a nonprofit
organization with tax-exempt status under Section of
Internal Revenue Code 501(c)(3) of the United States of
America.
UNITED
A non-profit organization
Scientific
Group
USG is led by a group of senior scientists as the board
of directors, who are committed to work together and
contribute their best services to the scientific community
by supporting scientific meeting organization and open
access content publication.
Publishing Partner
Frontiers in Pharmacology is a leading journal in its
field, publishing rigorously peer-reviewed research across
disciplines, including basic and clinical pharmacology,
medicinal chemistry, pharmacy, and toxicology. Field
Chief Editor Heike Wulff at UC Davis is supported by an
outstanding Editorial Board of international researchers.
This multidisciplinary open-access journal is at the forefront
of disseminating and communicating scientific knowledge
and impactful discoveries to researchers, academics,
clinicians, and the public worldwide.
BIO-NATURAL-2021, NOVEMBER 18-19, 2021 | VIRTUAL
DAY-01 THURSDAY NOVEMBER 18, 2021
08:45-09:00 Zoom Joining and AV Check
09:00-09:15 Welcome Address by:
Luis Monteiro Rodrigues, CBIOS Director, Universidade Lusófona, Portugal
Patrícia Rijo, CBIOS – Universidade Lusófona´s Research Center for Biosciences & Health
Technologies, Portugal
Chairs: Patrícia Rijo, CBIOS – Universidade Lusófona´s Research Center for Biosciences & Health
Technologies, Portugal
Andreia Rosatella, Universidade Lusófona´s Research Center for Biosciences & Health Technologies,
Portugal
Keynote Speakers
09:15-09:45 Keynote: Thomas Efferth, Johannes Gutenberg University, Germany
Speaking on: Covid-19: Epidemiology, Pathophysiology, Therapy
09:45-10:15 Keynote: Raymond J. Andersen, The University of British Columbia, Canada
Speaking on: Natural Product Drug Leads for Development of Host-Directed Therapies for
Pandemics
10:15-10:45 Keynote: Deniz Tasdemir, GEOMAR Centre for Marine Biotechnology, Germany
Speaking on: Marine Natural Product Research in the Omics Era
10:45-10:55 Break
Session I: Natural Products in Drug Discovery
Oral Talks
11:00-11:20 Patrícia Rijo, CBIOS – Universidade Lusófona´s Research Center for Biosciences & Health Technologies, Portugal
Diterpenoids from Plectranthus spp. as a starting tool in Drug Development
11:20-11:40 Mattia Mori, University of Siena, Italy
Selective Natural Product Modulators of DNA G-Quadruplex with Anticancer Potential
11:40-12:00 Daniela B B Trivella, Brazilian Biosciences National Laboratory, Brazil
NP3 Platform: Assisting New Discoveries from Natural Products
12:00-12:20 Celia Cabral, University of Coimbra, Portugal
Chemoprevention and Therapeutic Role of Phytochemicals in Glioblastoma
12:20-12:40 Mariana Almeida, Lab. Medinfar-prod. Farmacêuticos Sa, Portugal
Natural ingredients: Innovation in food supplements
12:40-13:00 Christopher N. Boddy, University of Ottawa, Canada
Armeniaspirols, A New Class of Gram-Positive Antibiotics that Target Clp Proteases
13:00-13:20 Daniele Passarella, Università degli Studi di Milano, Italy
Cannabidiol: intriguing target and creative building block
13:20-13:40 Maha Abdallah, Instituto de Biologia Experimental e Tecnológica, Portugal
Evaluation of Extracts Obtained from Marine By-products using Natural Eutectic Solvent
Systems for their Therapeutic Application in the Dry Eye Disease
13:40-14:15 Lunch
BIO-NATURAL-2021, NOVEMBER 18-19, 2021 | VIRTUAL14:15-14:35 Sónia Aguiar da Rocha, University of Porto, Portugal
Optimization of in vitro Experimental Conditions for Glycogen Phosphorylase Inhibition Assay
and Demonstration of High Inhibitory Effectiveness by Chromone Derivatives
14:35-14:55 Learn-Han Lee, Monash University Malaysia, Malaysia
Promising Novel Anti-MRSA Protein Derived from Novel Streptomyces Strain Isolated from
Malaysia’s Mangrove Forest
14:55-15:15 Bruno Botta, Sapienza University, Italy
Challenging Organic Synthesis Inspired by Nature: From Natural Products Chemistry to Drug
Discovery
15:15-15:35 Ru Angelie Edrada-Ebel, Strathclyde Institute of Pharmacy and Biomedical Sciences, University of
Strathclyde, UK
Using Concatenated NMR and MS Analytical Data for Metabolomic-guided Production and
Isolation of Bioactive Natural Products
15:35-15:55 Tanja Grkovic, National Cancer Institute, NIH, USA
Generation of Natural Product Libraries for High Throughput Screening
15:55-16:15 Jan Borlinghaus, RWTH-Aachen University, Germany
Allicin from Garlic Inhibits DNA Gyrase Activity in Bacteria
16:15-16:35 Daniel dos Santos, CBIOS-Universidade Lusófona Research Center for Biosciences & Health Technologies,
Lisbon, Portugal
ABC Transporters: From Multidrug Resistance to Cystic Fibrosis
16:35-16:55 Jaclyn Winter, University of Utah, United States
Harnessing the Chemical Potential of Unprecedented Microbes from the
16:55-17:15 Kumarappan Chidambaram, King Khalid University, Saudi Arabia
Ziziphus mauritiana Lam Attenuates Airway Inflammation via Downregulating NFκB Pathway in
Both in-vitro & in-vivo Models of Asthma
17:15-17:30 Break
Poster Presentations
17:30-17:40 P-01: Jessica Karina Díaz Cantón, Instituto de Química, UNAM, México
Evaluation of the Antidepressant Effect and Possible Mechanism of Action of the Essential Oil of
Litsea Glaucescens (Kunth) (Mexican laurel) Administered by Inhalation
17:40-17:50 P-02: Carlos Fernández Galleguillos, Universidad Austral de Chile, Instituto de Farmacia, Chile
Alkaloid Fingerprinting, Antiproliferative and Cholinesterase Inhibition Potential of Rhodophiala
Advena Bulbs
17:50-18:00 P-03: Eva María Domínguez-Martín, CBIOS – Universidade Lusófona’s
Research Center for Biosciences & Health Technologies, Portuga
Phytochemical Study and Anti-glioblastoma Activity Evaluation of Plectranthus Hadiensis
(Forssk.) Schweinf. Ex Sprenger Var. Hadiensis
18:00-18:10 P-04: Merilin Al Sharif, Institute of Biophysics and Biomedical Engineering, Bulgarian
Academy of Sciences, Sofia, Bulgaria
New Potential Pharmacological Targets of a Plant-derived Hydroxyanthraquinone from Rubia
Cordifolia L.
18:10-18:20 P-05: Rita Almeida, Chinese Academy of Sciences, Shanghai, China
Mining the Chemodiversity of Diterpenoids in Scutellaria Baicalensis
BIO-NATURAL-2021, NOVEMBER 18-19, 2021 | VIRTUALDAY-02 FRIDAY NOVEMBER 19, 2021
09:00-09:10 Zoom Joining and AV Check
09:10-09:15 Welcome Address by:
Luis Monteiro Rodrigues, CBIOS Director, Universidade Lusófona, Portugal
Patrícia Rijo, CBIOS – Universidade Lusófona´s Research Center for Biosciences & Health
Technologies, Portugal
Chairs: Mattia Mori, University of Siena, Italy
Patrícia Rijo, CBIOS – Universidade Lusófona´s Research Center for Biosciences & Health
Technologies, Portugal
Session II: Marine Natural Products
Oral Talk
09:15-09:35 Fabians Faisal Dinelsa, IPB University, Indonesia
Oxy-Polybrominated Diphenyl Ethers from the Indonesian Marine Sponge Lamellodysidea
Herbacea: Isolation, Reaction, Computational Study, and SAR
Poster Presentations
09:35-09:45 P-06: Alejandra Yoselin González-Muñiz, Iinstituto Nacional De Neurología y Neurocirugía Manuel
Velasco Suárez (INNNMVS), México
Antineoplastic Extracts from the Giant Deep-sea Worm Riftia Pachyptila on Glioblastoma Cells
09:45-09:55 P-07: Saif Aldeen Jaber, University of Strathclyde, United Kingdom
Implementing Metabolomic Tools for the Isolation of Anti-biofilm Metabolites from Endophytic
Dendryphiella Salina Isolated from Scottish Marine Laminaria Hyperborea
Session III: Natural Cosmetics
Oral Talk
09:55-10:15 Duha Alamoudi, University college London (UCL), United Kingdome
Trends in Nanotechnology for Skin Anti-Aging Strategies and the Formulation of Bakuchiol in a
Novel Nanocarrier
Poster Presentations
10:15-10:25 P-08: Cíntia Almeida, CBIOS – Universidade Lusófona’s Research Center for Biosciences & Health
Technologies, Portugal
Using Lipids Extracted from Black Soldier Fly Larvae for Nanoparticles Development - Preliminary
Studies
10:25-10:35 P-09: Ines Calamote, Universidade Lusófona de Humanidades e Tecnologias, Portugal
Innovative Formulations Loading Phytochemicals to Tackle Skin Ageing: Preliminary Studies
Session IV: Natural Products Chemistry
Oral Talks
10:35-10:55 Chi Godloves Fru, University of Buea, Cameroon
Saponins from Raphia Vinifera Fruit and their Cytotoxic Activity
10:55-11:15 Fernando Reyes, Fundación MEDINA, Spain
Structural Elucidation of Complex Microbial Natural Peptides Aided by Biosynthetic Gene
Cluster Analysis
BIO-NATURAL-2021, NOVEMBER 18-19, 2021 | VIRTUAL11:15-11:35 Frank Hahn, University of Bayreuth, Germany
Exploiting the Biosynthetic Pathways of Antifungal Polyketides as a Source for Novel
Chemoenzymatic Tools
11:35-11:55 Diana Pinto, University of Aveiro, Portugal
Can Underexplored or Medicinal Species be Exciting Ingredients in the Formulation of Smart
Foods or Natural Medicines?
11:55-12:15 Helena Mannochio Russo, Institute of Chemistry, Sao Paulo State University, Brazil
Use of Statistical Tools to Accelerate the Natural Products Workflow – A Malpighiaceae Case Study
12:15-12:35 Anjar Purba Asmara, University of Technology Sydney, Australia
Antioxidant and α-glucosidase Inhibitory Activities of Acacia Saligna Extracts
12:35-13:00 Lunch
Chairs: Patrícia Rijo, CBIOS – Universidade Lusófona´s Research Center for Biosciences & Health
Technologies, Portugal
Ana Mourato, University of Lisbon, Portugal
Poster Presentations
13:00-13:10 P-10: Vera M.S. Isca, Universidade Lusófona de Humanidades e Tecnologias, Lisboa, Portugal
New Hit Ester Derivatives to Target Protein Kinase C Isoforms using A Natural Diterpenoid
13:10-13:20 P-11: Epole Ntungwe, CBIOS – Universidade Lusófona´s Research Center for Biosciences & Health
Technologies, Portugal
Self-assembly Nanoparticles of Three Abietane Diterpenes from Plectranthus Species
13:20-13:30 P-12: Ana C. Zanatta, São Paulo State University (Unesp), Institute of Chemistry, Brazil
Multivariate Statistical Analysis to Evaluate the Effects of Environmental Factors on the
Chemical Profile of Serjania Marginata Casar. Leaves
13:30-13:40 P-13: Izabela Grzegorczyk-Karolak, Medical University of Lodz, Poland
Production of Bioactive Polyphenols in Salvia Viridis Shoots Cultivated in Temporary Immersion
System
13:40-13:50 P-14: Skała Ewa, Medical University of Lodz, Poland
Production of the Essential Oil by Codonopsis Pilosula (Franch.) Nannf. Transformed Roots
Oral Talks
13:50-14:10 Andrea A Stierle, University of Montana, MT, USA
Elicitation of Cryptic Biosynthesis in the Search for New Antibiotics from Extremophilic Fungi
14:10-14:30 Jakob Magolan, McMaster University, Canada
Chemical Synthesis of Prenylated Phenolic Natural Products
Session V: Other Fields Related to Natural Products
Poster Presentations
14:30-14:40 P-15: Fatema Aljishi, UCL School of Pharmacy, London, United Kingdom
Morinda Perspective use in the Treatment of Skin Conditions: A Review
14:40-14:50 P-16: Ana Júlio, CBIOS-Research Center for Biosciences & Health Technologies, Lusófona University, Portugal
The Role of Bioderived Ionic Liquids in Topical Formulations Containing Hydroxycinnamic Acids
14:50-15:00 P-17: Lukasz Kuzma, Medical University of Łódź, Poland
Biomass Accumulation and Phenolic Acid Biosynthesis in Salvia Austriaca Jacq. Hairy Root
Culture Grown in Erlenmeyer Flasks and in Temporary Immersion Bioreactor RITA®
BIO-NATURAL-2021, NOVEMBER 18-19, 2021 | VIRTUAL15:00-15:10 P-18: Henoc del Rosario García, Instituto Universitario de Investigaciones Biomédicas y Sanitarias, Spain
Structure-activity Relationships Reveal a 2’-furoyloxychalcone as a Potent Cytotoxic and
Apoptosis Inducer in Human U-937 Leukaemia Cells
15:10-15:20 P-19: Carolina P. Reyes, Universidad de La Laguna, Spain
Canarian Cyanobacterias as a Potential source of Fungicide Natural Products
15:20-15:30 Break
VI: Bioactivity of Natural Products
Oral Talk
15:30-15:50 Claudio Ferrante, Università degli Studi “Gabriele d’Annunzio”, Italy
Comparative Investigation of Composition, Antifungal, and AntiInflammatory Effects of the
Essential Oil from Three Industrial Hemp Varieties from Italian Cultivation
15:50-16:10 Tobias A. M. Gulder, Technical University of Dresden, Germany
Biosynthetic Enzymes as Tools for Natural Product Synthesis in Vivo and in Vitro
Poster Presentations
16:10-16:20 P-20: Przemysław Sitarek, University of Lodz,Poland
Biological Activity of Leonotis nepetifolia (L.) R. Br Transformed Roots Extracts Obtained
through Rhizobium rhizogenes-Mediated Transformation
16:20-16:30 P-21: Dana Atoum, University of Strathclyde, United Kingdom
Use of Multivariable Data Analysis Comparison For Unravelling the Anticancer and Antioxidant
Differences Between Two Endemic Varieties of Chamomile
16:30-16:40 P-22: Ebtihal Althomaly, University College London, United Kingdom
How Effective are Natural Products at Improving Muscle Strength and Function in Older Adults?
16:40-16:50 P-23: Ester Gloria Saavedra Díaz, Universidad de Las Palmas de Gran Canaria, Spain
Natural Occurring Chlorinated Guaianolide Linichlorin a Induces Apoptosis Dependent on
Reactive Oxygen Species Generation in Human U-937 Leukaemia Cells
16:50-17:00 P-24: Sandra Ferreira, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies,
Portugal
Evaluation of the Lysyl Oxidase Like 2 (Loxl2) Inhibitory Activity of a Natural Pimarane and its
Sugar Derivatives
17:00-17:10 P-25: Gabrielle Bangay, Universidade Lusófona de Humanidades e Tecnologias, Portugal
Royleanone Diterpenoids from Plectranthus spp. as P-glycoprotein Inhibitors
17:10-17:20 P-26: Sofia Ferreira, Universidade Lusófona de Humanidades e Tecnologias, Portugal
Urolithin B hinders IAPP Aggregation: A Potential Role of Diet-derived Metabolites towards
Diabetes Management
17:20-17:30 P-27: Márcia Filipe, CBIOS – Center Research for Biosciences & Health Technologies, Lisbon, Portugal
Medicinal Centauri Honey: Chemical Composition and Antioxidant Properties
17:30-17:40 P-28: Márcia Santos Filipe, CBIOS – Center Research for Biosciences & Health Technologies, Lisbon, Portugal
Novel Masks Impregnated with Antioxidant Essential Oils
17:40-17:50 P-29: Iris Guerreiro, CBIOS – Universidade Lusófona’s Research Center for Biosciences & Health Technologies,
Portugal
Plant Polyphenols and Renal Heath: The Relevance of Bioavailability
BIO-NATURAL-2021, NOVEMBER 18-19, 2021 | VIRTUALSession VII: Functional Foods and Food Supplements
Oral Talk
17:50-18:10 Xinglin jiang, Technical University of Denmark, Kongens Lyngby, Denmark
Distribution of Poly-L-Lysine Synthetases in Coryneform Bacteria Isolated from Cheese and
Human Skin
Poster Presentation
18:10-18:20 P-30: Marisa Nicolai, CBIOS-Universidade Lusófona de Humanidades e Tecnologias, Portugal
Phenolic Compounds in Portuguese Grape Pomace Flour
18:20-18:30 P-31: Bruno Gonçalves, Research Institute for Medicines (iMed.ULisboa), Universidade de Lisboa, Portugal
Molecular Dynamics Study of the ABCG2 Structural Changes induced by ATP and Substrate
Binding
18:30-18:40 Concluding Remarks by the Chair
For More Information: https://bionaturalconference.com/
BIO-NATURAL-2021, NOVEMBER 18-19, 2021 | VIRTUALUNITED
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