AEROSPACE MEDICINE YOU - and - January February 2022

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AEROSPACE MEDICINE YOU - and - January February 2022
January/February 2022

    AEROSPACE
    MEDICINE                                       and
                                                   YO U

           Federal Aviation   8   BasicMed is     11    ow to Fast-Track
                                                        H                    22   
                                                                                  Who’s Who in the Office
           Administration          Turning Five!        Your Medical              of Aerospace Medicine
                                                                                                   January/February 2022 1
AEROSPACE MEDICINE YOU - and - January February 2022
ABOUT THIS ISSUE…

    U.S. Department
    of Transportation
    Federal Aviation
    Administration

    ISSN: 1057-9648
    FAA Safety Briefing
    January/February 2022
    Volume 61/Number 1                                                                   The January/February 2022 issue of FAA Safety Briefing focuses
                                                                                         on aerospace medicine. Articles discuss the pilot medical certi-
    Pete Buttigieg Secretary of Transportation                                           fication process and the various roles and responsibilities of the
    Steve Dickson Administrator                                                          FAA’s Office of Aerospace Medicine.
    Chris Rocheleau Acting Associate Administrator for Aviation Safety
    Robert C. (Rico) Carty Acting Executive Director, Flight Standards Service
    Susan K. Parson Editor
    Tom Hoffmann Managing Editor
    James Williams Associate Editor / Photo Editor
    Jennifer Caron Copy Editor / Quality Assurance Lead
    Paul Cianciolo Associate Editor / Social Media
    John Mitrione Art Director

    Published six times a year, FAA Safety Briefing, formerly
    FAA Aviation News, promotes aviation safety by discussing current technical,
    regulatory, and procedural aspects affecting the safe operation and                  Contact Information
    maintenance of aircraft. Although based on current FAA policy and rule               The magazine is available on the internet at:
    interpretations, all material is advisory or informational in nature and should      www.faa.gov/news/safety_briefing
    not be construed to have regulatory effect. Certain details of accidents
    described herein may have been altered to protect the privacy of those involved.     Comments or questions should be directed to the staff by:
                                                                                         •  Emailing: SafetyBriefing@faa.gov
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2    FAA Safety Briefing
AEROSPACE MEDICINE YOU - and - January February 2022
D E PA R T M E N T S

                                                                                                2	Jumpseat: an executive policy
                                                                                                   perspective
The FAA Safety Policy Voice of Non-commercial General Aviation
                                                                                                3	ATIS: GA news and current events

                                                                                                  Aeromedical Advisory: a checkup on
                                                                                                5	
                                                                                                  all things aeromedical

                                                                                                6	Condition Inspection: a look at
                                                                                                   specific medical conditions

                                                                                                26	Checklist: FAA resources and safety
                                                                                                    reminders

                                                                                                27	Drone Debrief: drone safety roundup

                                                                                                28	Nuts, Bolts, and Electrons: GA
                                                                                                    maintenance issues

                                                                                                29	Angle of Attack: GA safety strategies

                                                                                                30	Vertically Speaking: safety issues for
         Who’s Who in the Office of Aerospace Medicine                                              rotorcraft pilots

22       A Behind-the-Scenes Look at the FAA’s Aerospace Medicine Decision Makers               31	Flight Forum: letters from the Safety
                                                                                                    Briefing mailbag

                                                                                                32	Postflight: an editor’s perspective

                                                                                                Inside back cover
                                                                                                FAA Faces: FAA employee profile

         Smooth is Fast                                       The Human Factor
11       How to Speed Up Your
          Medical Certification
                                                      15      How The FAA’s Medical and Human
                                                              Factors Research Helps Aviation

  BasicMed is Turning Five!
8	
  How It Works, and How It’s Making a Difference

18	Courses, Sources, and Training Resources
     What Pilots Can Learn from the FAA’s Aerospace
      Medical Education Division

                                                                                                                             January/February 2022 1
AEROSPACE MEDICINE YOU - and - January February 2022
JUMPSEAT                                                ROBERT C. (RICO) CARTY, FLIGHT STANDARDS SERVICE ACTING EXECUTIVE DIRECTOR

    PILOT MAINTENANCE

    If you are anything like me, you                                                              as the traditional avenues to medical
    probably think of going to the doctor                                                         certification) is about using open
    with the same kind of reluctance you                                                          communication with your provider to
    might have for, say, launching into                                                           find any health problems that could
    lousy weather. But where avoiding                                                             adversely affect your ability to oper-
    bad weather in a small GA airplane                                                            ate an aircraft safely, to use the most
    can help you stay alive, skipping or                                                          appropriate treatments to fix those
    delaying visits to your doctor could                                                          problems, and to monitor results to
    have the opposite effect.                                                                     ensure that any health/safety issues
       A key part of remaining physically                                                         are fully resolved.
    healthy is an activity that is similar to
    the things you do to keep your airplane                                                       Questions?
    mechanically sound: constant monitor-                                                         There are lots of resources available
    ing and regular maintenance. One of                                                           nowadays from both the FAA and
    the earliest skills we learn as pilots is to                                                  aviation community organizations.
    recognize and address small signs (e.g.,                                                      If you think you might have an issue,
    why is that gauge reading low?) before                                                        here are some things you can do.
    they become big problems (e.g., my                                                               Get the facts. Use all available
    engine just quit!). Regular visits to the         Second is the FAA’s Compliance              resources to learn as much as you can
    doctor are an important part of keeping        Program, first introduced in 2015.             about the certification implications
    your flying physiology in top form, so         The Compliance Program is the                  of your particular medical condition.
    you can find and address little problems       enabling guidance for the FAA’s risk-          A good place to start is the medical
    before they become more serious.               based oversight approach to compli-            certification home page on the FAA’s
       Many pilots, though, have perhaps           ance. It stresses a problem-solving            website (www.faa.gov/pilots/medical).
    been hesitant to fully communicate             approach where enhancement of the              You can also access the FAA MedX-
    with their doctors for fear of compli-         individual or organization’s safety            Press form from this page.
    cating issuance of the all-important           performance is the goal. It promotes              Use your resources. The Aircraft
    medical certificate. But we have all           communication, collaboration, and              Owners and Pilots Association
    benefited from several developments            proactive risk management to find              (AOPA), the Experimental Aircraft
    over the past few years.                       safety problems before they cause an           Association (EAA), and many other
                                                   accident and use the most effective            aviation organizations provide med-
    Continuous Improvement                         tools to ensure a positive, permanent          ical certification information, advice,
    First is the hard work the FAA’s med-          fix. This approach certainly applies to        and advocacy for their members.
    ical certification staff has done over         managing your health. It has always               Resolve the problem. Work with
    the past few years, not only to speed          been the case that the FAA expects             your physician to resolve any issues
    consideration of special issuance              compliance on medical requirements,            that might delay issuance of your
    but also to expand both the range of           and it has always been the case that           medical certificate.
    certifiable conditions and the avenues         compliance includes honest com-                Document. Learn exactly what the
    available. These include AASI (AME             munication about issues that affect            FAA needs to certify your condition.
    Assisted Special Issuance) and CACI            your health, and thus your ability to          Have your physician document your
    (Conditions AMEs Can Issue). The               operate an aircraft safely.                    condition, your treatment, and your
    list of CACI-eligible conditions is               Third is the advent of BasicMed.            prognosis in precisely the format and
    expanding and, as you will read else-          BasicMed leaves no excuse for any-             level of detail the FAA requires.
    where in this issue, all kinds of other        thing but a full and frank discussion          Doing your part will speed the FAA’s
    improvements to the medical certifi-           with your state-licensed physician             evaluation and get you back on the
    cation process are in the works.               about your health. BasicMed (as well           flight deck as quickly as possible.

2   FAA Safety Briefing
AEROSPACE MEDICINE YOU - and - January February 2022
GA NEWS AND CURRENT EVENTS                                                                                                                           ATIS

AVIATION NEWS ROUNDUP

Open and Close Flight Plans via             The enhancement is available to                           your account. If you call from a differ-
Phone                                       all pilots who have a free online                         ent phone number, the system cannot
Leidos Flight Service released a new        1800wxbrief.com account linked to a                       look up your flight plan.
feature that allows pilots to activate      primary phone number. To sign up for                         Note that the IVR system will not
and close VFR flight plans via the          an account, click Create Account and                      offer services if it detects more than
Interactive Voice Response (IVR)            enter a primary phone number associ-                      one proposed flight plan with the
system without talking to a special-        ated with your account.                                   same departure time, and pilots will be
ist. This upgrade makes opening and            When you call 1-800-WX-BRIEF,                          unable to use the system to close flight
closing VFR flight plans easier than        the system will automatically search                      plans that have entered Search and
ever and saves pilots valuable time by      to see if you have a flight eligible to                   Rescue status. Visit 1800wxbrief.com
eliminating hold times.                     Activate or Close and provide menu                        to learn more about the IVR feature
                                                                 options. The sys-                    and future updates.
                                                                 tem will not offer
                                                                 these menu options                   Dangerous Laser Strikes Continue
                                                                 if there is no flight                to Rise
                                                                 plan on file. You                    Shining a laser at an aircraft is a serious
                                                                 can activate your                    safety threat that continues to rise. As
                                                                 VFR flight plan                      of Oct. 14, the FAA has received 7,186
                                                                 up to 30 minutes                     laser strike reports for 2021, exceeding
                                                                 in the future to                     the 2020 total of 6,852. This marks the
                                                                 ensure that you                      highest number of reports since 2016.
                                                                 have enough time                        Several types of high-powered
                                                                 to get into the air                  lasers can completely incapacitate
                                                                 before the flight                    pilots, many of whom are flying air-
                                                                 plan is active.                      planes with hundreds of passengers.
                                                                 You can easily                       People who shine lasers at aircraft
                                                                 close a flight plan                  face FAA fines of up to $11,000
                                                                 when your flight                     per violation and up to $30,800 for
                                                                 has concluded                        multiple laser incidents. In 2021, the
                                                                 by calling Leidos                    FAA issued $120,000 in fines for laser
                                                                 Flight Service from                  strikes. Violators can also face crimi-
                                                                 the primary phone                    nal penalties from federal, state, and
                                                                 number linked to                     local law enforcement agencies.

  SAFETY ENHANCEMENT TOPICS                            Please visit bit.ly/GAFactSheets for more information on these and other topics.

                                    JANUARY                                                                      FEBRUARY
                                    ADM and Startle Response —                                                   Stall/Spin/Upset Recovery
                                    Understanding the human startle                                              Training —
                                    response and effectively coping                                              How training and education in
                                    with unexpected events.                                                      stalls, spins, and upset recovery
                                                                                                                 can help reduce loss of control
                                                                                                                 accidents.

                                                                                                                                          January/February 2022 3
AEROSPACE MEDICINE YOU - and - January February 2022
ATIS

       To identify laser strike trends, the   data reporting and forecasting              America (BFA) on an accreditation
    FAA developed a visualization tool        — including continued testing of            program. The program includes
    using the Tableau software platform       Visual Weather Observation Systems          voluntary standards for pilots and
    that shows laser strike data from         (VWOS), expanding satellite-based           operators and offers multiple tiers of
    2010 to 2020 and highlights trends        Automatic Dependent Surveil-                BFA safety accreditation.
    by geographic area, per capita data,      lance-Broadcast (ADS-B) air-traffic            You can find the draft medical
    and time of day and year. The FAA         control coverage to more areas, and         rule in the Federal Register at
    shares the information to draw            improving navigation charting. The          bit.ly/NPRM-balloon, and the public
    attention to the dangerously high         FAA will begin developing a roadmap         comment period closes on Jan. 18.
    rate of laser strikes on airplanes.       for implementing the recommen-
    You can download laser report data        dations in the near- and mid-term,          Three Military Airports Now
    by year from the FAA’s website at         focusing on initiatives with the great-     Eligible for Funding to Add Civilian
    faa.gov/about/initiatives/lasers/laws.    est safety benefits.                        Operations
       The FAA remains vigilant to                The FAA will develop a draft road-      The FAA has selected three airports
    raise awareness about the dangers         map by mid-February 2022, identify          to be eligible for grants to add civil-
    of pointing lasers at aircraft and        the resources necessary to implement        ian aviation operations at former
    encourages the public to report laser     it and seek aviation stakeholder feed-      and current military airfields, adding
    strikes (bit.ly/LaserRpt) to the FAA      back on the roadmap through May             system capacity and helping to reduce
    and local law enforcement agencies.       2022. The FAA will continue those           congestion at existing airports. Kelly
                                              initiatives already underway and            Field in San Antonio, Texas; Mobile
    Increasing Aviation Safety in Alaska      incorporate parts of the new initia-        Downtown Airport in Mobile, Ala.;
    Last October, the FAA released            tives by summer 2022. The agency will       and Salina Regional Airport in Salina,
    recommendations (faa.gov/alaska)          submit a progress report to stakehold-      Kan., can now apply for Airport
    on how to increase aviation safety in     ers by September 30, 2022.                  Improvement Grants.
    Alaska after a year-long, sweeping                                                       The Military Airport Program
    examination of safety issues specific     Proposed Medical Requirements for           (MAP) provides funding as a set aside
    to the challenges of flying in Alaska,    Commercial Hot-Air-Balloon Pilots           of the Airport Improvement Program
    where more than 80% of its commu-         In November, the FAA proposed a rule        (AIP) to help increase civilian aviation
    nities are accessible only by air.        requiring commercial hot-air-balloon        capacity at current or former military
       Among the recommendations are:         pilots to hold medical certificates         airports. MAP funds projects such
    increasing and improving weather          when operating for hire. The rule           as surface parking lots, fuel farms,
                                                         would mandate a sec-             hangars, utility systems, access roads,
                                                         ond-class medical certificate,   cargo buildings, and other airfield-re-
                                                         the same standard required       lated infrastructure.
                                                         for commercial pilots.              The MAP allows the FAA to des-
                                                            Currently, commercial         ignate up to 15 joint-use or former
                                                         balloon pilots are exempt        military airports to participate each
                                                         from the medical require-        fiscal year. Three of the 15 airports
                                                         ment. In the FAA Reau-           may be general aviation airports, and
                                                         thorization Act of 2018,         the remaining 12 must be commercial
                                                         Congress directed the            service or reliever airports. Selected
                                                         FAA to revise the medical        airports are designated for a period of
                                                         certification standards for      one to five years. Previously selected
                                                         commercial balloon pilots.       airports may re-apply to the program.
                                                         The draft rule also addresses       The airports in this program have
                                                         a NTSB recommendation            unique project-eligibility rules to
                                                         that the FAA remove the          convert them to civilian or joint use,
                                                         exemption.                       thereby increasing the capacity of the
                                                            The FAA in recent years       National Airspace System to serve
                                                         took steps to increase the       the flying public. Since 1991, the FAA
                                                         safety of hot air balloon        has provided approximately $764
                                                         tourism by working with          million to more than 35 airports
                                                         the Balloon Federation of        through the program.

4   FAA Safety Briefing
AEROSPACE MEDICINE YOU - and - January February 2022
DR. SUSAN NORTHRUP, FAA FEDERAL AIR SURGEON                                                 AEROMEDICAL ADVISORY

MIND YOUR MEDS!

Pilots often ask which medications are        against kidney disease in individuals      Do Not Fly list in the AME Guide
permissible for flight and where they         with diabetes. It can be acceptable for    (bit.ly/NoIssueOrFly).
can find this information.                    all of these conditions.                      Hydrocodone/Acetaminophen
   Let’s check out some of the top               Albuterol (Accuneb®, Ventolin,          (Lortab®, Vicoden®, Norco®): these
prescription medications in the               Proair®, Proventil®): this medication      pain medications can cause sedation
United States (according to GoodRx.           is used to treat wheezing and short-       and/or dizziness and are unacceptable
com) and review how we consider               ness of breath from asthma or COPD.        for flight. Besides, if you need a nar-
them for medical certification.               Review the CACI Asthma worksheet           cotic pain medication, you shouldn’t
Here's a link to the Pharmaceuticals          (bit.ly/CACIAsthma) (PDF), and             be flying. These medications are also
(Therapeutic Medications) section of          bring a copy to your personal doctor,      found on the DNI-DNF list and in
the AME Guide for further guidance            so they know which medications are         the Medications and Flying brochure
(bit.ly/AMEGuideTherapeutics).                acceptable for flight. Be sure to tell     (bit.ly/MedsFlying) (PDF).
                                              your AME what you use, how often              Diphenhydramine (Benadryl®):
Usually Acceptable:                           you use it, and why.                       this is a common component in over-
Atorvastatin (Lipitor®): this medica-            Levothyroxine (Synthroid®, Uni-         the-counter (OTC) sleep medications,
tion is used for high cholesterol and         throid®, Levoxyl®): this medication is     many cough and cold combination
is allowed if the user experiences no         used for hypothyroidism. Review the        medications, and some allergy medi-
significant side effects. Like any accept-    CACI Hypothyroidism Worksheet              cations. It is the most common medi-
able medication, wait at least 48 hours       (bit.ly/CACIHypothyroidism) (PDF).         cation seen in fatal aircraft accidents.
(some need a longer ground trial) after       Provide a copy to your personal doc-       If you take it, you should not fly for
the first dose to make sure you have no       tor to help ensure that their clinical     60 hours after the last dose. If you
problems with the medication.                 note includes the information we need      need a medication for a cold, flying is
   Lisinopril (Prinivil, Zestril):            for medical certification.                 not a good idea anyway. For accept-
an angiotensin converting enzyme                 Metformin (Glucophage) for Dia-         able allergy medications, check out
inhibitor (ACE-I) used for high               betes: check out the Acceptable Com-       the Allergy — Antihistamine page
blood pressure or heart failure. Most         binations of Diabetes Medications          (bit.ly/AllergyAntihistamine) (PDF).
high blood pressure medications are           (bit.ly/ComboDiabetesMeds) (PDF).
allowed after a seven day ground              This two-page chart lets you, your         OTC Medication Example:
trial. Review the disposition tables          AME, and (if you bring them a copy)        Omeprazole (Prilosec): this is an
here (bit.ly/HeartHypertension) to            your personal physician know what          OTC medication used to reduce
see what information you need from            medications the FAA allows for pilots      stomach acid in many underlying
your personal physician for your              and how long you must wait to return       conditions like heartburn, GERD,
AME to issue a medical certificate            to active flying after starting, adding,   or ulcers. It is also available as
under Conditions an AME Can Issue             or changing diabetes medication.           a prescription medication in a
(CACI). Another resource is this FAQ                                                     higher dose. If you need an OTC
page (bit.ly/HeartHypertensionFAQs)           Unacceptable for Flight:                   medication, start here: What OTC
(PDF) which you’ll also find helpful          Gabapentin (Neurontin®): used              medications can I take and still be
for these next two medications.               for seizures, nerve pain, or shingles      safe to fly? (bit.ly/OTCMedstoFly)
   Amlodipine (Norvasc®): a calcium           pain, this medication can make you            When in doubt about medications,
channel blocker (CCB) used for high           drowsy or dizzy, may slow your             ask your AME. Your personal physi-
blood pressure. If you take it for any        thinking, and cause loss of coor-          cian might not understand the impli-
other reason, let your AME know why.          dination. In fact, the prescription        cations of many medications and/or
   Losartan (Cozaar): an angiotensin          insert warns you not to drive a car or     conditions for flight safety. Ask them
II receptor blocker (ARB) used for            operate heavy machinery. Neurontin         a simple question — Would they feel
high blood pressure. It also reduces          and similar sedating medications are       safe on an airplane if THEIR pilot was
the likelihood of stroke and protects         referenced on the Do Not Issue —           using this medication?

                                                                                                                  January/February 2022 5
AEROSPACE MEDICINE YOU - and - January February 2022
CONDITION INSPECTION                                                      CHRIS M. FRONT, PSY.D. AND RANDY J. GEORGEMILLER, PH.D.

    PILOTS WITH ATTENTION-DEFICIT/HYPERACTIVITY DISORDER (ADHD)

    Safety experts agree that at least 70%      easily distracted, wandering off task,         suming process. Medical providers,
    of aviation accidents are attributable      and having difficulty sustaining focus.        acting under time pressure and
    to the pilot. NASA scientists report        Hyperactivity refers to excessive motor        attempting to respond to the concerns
    that most accidents result from some        activity or excessive restlessness, or         of patients (or their parents), some-
    failure in the pilot’s cognitive perfor-    talkativeness. Impulsivity refers to           times prescribe medication to treat
    mance, with distractions and errors in      hasty actions without adequate con-            ADHD or assign a diagnosis without
    aeronautical decision making (ADM)          sideration of possible consequences,           adequate evidence of the disorder. The
    most prominent.                             despite a high potential for harm.             result is a subset of the adult pop-
       For example, when a pilot decides            NTSB investigations of fatal               ulation with a documented history
    to launch into marginal VFR con-            accidents attributed to ADHD have              of treatment for ADHD — some of
    ditions, continues as conditions            documented that pilots with ADHD:              whom truly had the condition and
    deteriorate, enters IMC, and loses          failed to adequately prepare for flight        others who probably did not.
    control of the aircraft, the fatal crash    (e.g., did not check the weather), con-           To determine if the adverse
    may be categorized as a “loss of con-       tinued flight when it was ill-advised          impact of ADHD is present or not,
    trol” event, but it was rooted in poor      (e.g., due to deteriorating weather),          the FAA requires a thorough evalu-
    ADM. Even experienced pilots with           engaged in hazardous actions (e.g.,            ation by a licensed psychologist. It
    no impairing conditions occasionally        low-level maneuvering to show off),            is most beneficial to see a psycholo-
    make errors in ADM or get dis-              and became distracted and made criti-          gist familiar with the FAA’s specific
    tracted. That fact led to the emphasis      cal errors (e.g., failed to maintain air-      protocols and standards. AMEs
    on CFIs creating realistic distractions     speed, stalled, and spun while circling        have access to a list of FAA-eligible
    in flight to teach effective distraction    a friend’s home at low altitude). Due          providers to assist with referrals. The
    management, as well as scenar-              to the risks to flight safety posed by         FAA’s evaluation requirements for a
    io-based training and formal risk           ADHD, regulatory authorities world-            history of ADHD are available at the
    assessment tools to improve ADM.            wide consider ADHD a disqualifying             following link: bit.ly/AMEGuide.
       The likelihood of an accident            condition for pilots.                             Upon review, the FAA will either
    rooted in distraction or poor ADM               Unfortunately, pilots sometimes fail       deny the pilot’s application or grant
    is heightened when the pilot has a          to disclose ADHD to their Aviation             an unrestricted or Special Issuance
    condition that negatively affects such      Medical Examiner (AME). The result             (SI) medical certificate. If the pilot
    skills. Attention-Deficit/Hyperactivity     is that the FAA learns about the con-          receives a time-limited SI, further
    Disorder (ADHD) is a neurodevel-            dition after a fatal accident when the         monitoring and assessment may be
    opmental disorder with symptoms of          toxicology results reveal the presence         required. While time-consuming
    inattention and/or hyperactivity-im-        of medication used to treat ADHD.              and costly, based on the safety risks
    pulsivity that interfere with function-     Notably, pharmacological treatments            posed by the symptoms of ADHD,
    ing or development. ADHD occurs             for ADHD are not approved for flying           the FAA has established this evi-
    in approximately 5% of children and         because they can cause harmful effects         dence-based risk assessment proto-
    frequently persists into adulthood,         on perceptual, motor, and cognitive            col to safeguard both the pilot and
    affecting about 2.5% of adults.             functions and impair the recognition           the national airspace system.
       Three subtypes of ADHD are based         of fatigue. Additionally, their effec-
    on the symptoms exhibited: a “pre-          tiveness is time-limited, a particular         Chris M. Front, Psy.D., is an instrument and multi-engine-
    dominantly inattentive” presentation,       concern if a dose is missed or flight          rated commercial pilot and clinical psychologist in the
    a “predominantly hyperactive/impul-         time exceeds the therapeutic impact            FAA’s Office of Aerospace Medicine. He is board certified in
                                                                                               assessment psychology. Randy J. Georgemiller, Ph.D., is a
    sive” presentation, and a “combined”        of the drug.                                   neuropsychologist in the FAA’s Office of Aerospace Medicine
    presentation. All three include symp-           Complicating the picture is the fact       and is board certified in clinical psychology.
    toms that pose a hazard to flight safety.   that an inaccurate diagnosis of ADHD
       Inattention manifests behaviorally       is not uncommon. Proper diagnosis
    in ADHD as being disorganized,              of ADHD is a complex and time-con-

6   FAA Safety Briefing
AEROSPACE MEDICINE YOU - and - January February 2022
FROM
          THE
    FLIGHT
       DECK
     FEDERAL AVIATION ADMINISTRATION
                PRODUCTION

 know before you go.

faa.gov/go/fromtheflightdeck

           NOW PLAYING
AEROSPACE MEDICINE YOU - and - January February 2022
BasicMed
                           Is Turning

                           Five!
                            How It Works,
                            and How It’s Making a Difference                                                 By Tom Hoffmann

    O
          n May 1, 2017, the FAA ushered in a new alternative          costs and enhancing the convenience and efficiency of the
          to airman medical certification. BasicMed marked a           medical certification process.
          tremendous shift in how some pilots can meet required
    medical qualifications for conducting lower-risk, non-com-         The Requirements
    mercial flying. Nearly five years later, more than 50,000 pilots   BasicMed has specific requirements for the airman, the
    (myself included) are currently flying under BasicMed.             type of aircraft you fly, and the type of operations you can
       While it has been popular for many pilots to pursue             perform. Here’s the breakdown:
    this alternative medical certification, some users still have
                                                                          Airman: You’ll likely qualify for BasicMed (most pilots
    a learning curve, especially as many near the first set of
                                                                       do), but here’s what you’ll need:
    renewal periods for operating under BasicMed. We can
    help. We’ll review key steps you’ll want to consider for both      • A current and valid U.S. driver’s license.
    starting and maintaining BasicMed coverage. We’ll also             • A valid FAA medical certificate, held at any point after July
    look at some of the research the FAA has completed in its            14, 2006. If that medical certificate was associated with
    five-year look back report to Congress to see how the pro-           a Special Issuance, the expiration of the Special Issuance
    gram is making a difference in the aviation community.               must be after July 14, 2006. Your most recent medical
                                                                         certificate must not have been suspended or revoked, and
    The Basics                                                           any Special Issuances must not have been withdrawn. Also,
    BasicMed permits certain pilots flying certain aircraft              if you’ve since applied for another medical certificate, that
    to conduct certain operations without holding a current              completed application cannot have been denied.
    medical certificate. (Don’t worry, we’ll be “certain” to explain   • Pilots who have ever had certain mental, cardiac, or
    those conditions below.) It is important to recognize upfront        neurological health conditions will need a one-time-only
    that BasicMed is an alternative to the third-class medical           Special Issuance medical certificate for each condition.
    certificate. It is not a replacement, and it is not a “fourth-       Suppose you haven’t had a Special Issuance for that
    class” certificate.                                                  condition, and you currently have, or you are newly
       Relief measures that come with choosing BasicMed                  diagnosed with, one of the cardiovascular, neurological,
    include using a valid U.S. driver’s license as a means               or mental health conditions described in the list of spe-
    of maintaining medical compliance with the program                   cial conditions. In that case, you may not use BasicMed
    (provided you’ve held an FAA medical after July 16, 2006)            until you have been issued a medical certificate with an
    and using a state-licensed physician (like your regular              authorization for Special Issuance. For the list of special
    family doctor) to perform the exam and sign off on your              conditions, see Medical Conditions Requiring One Spe-
    fitness for flight. Both provisions were aimed at lowering           cial Issuance at faa.gov/go/basicmed.

8   FAA Safety Briefing
• Aircraft: Under BasicMed, you may fly aircraft that:            sive Medical Examination Checklist (CMEC) found here:
• Has a maximum certificated takeoff weight of not more           bit.ly/BasicMedCMEC. If the section you’re required to fill
  than 6,000 pounds.                                              out looks familiar, it should — it’s derived from a previous
                                                                  version of FAA Form 8500-8, the medical certificate appli-
• Is authorized under federal law to carry not more than
                                                                  cation form that now exists in MedXPress.
  six occupants. Please note that in the last four years,
                                                                     Section 2 of the form requires you to answer questions
  supplemental type certificates are now available for
                                                                  about your medical history. Your physician will review
  certain aircraft certificated for more than six seats so that
                                                                  your responses to those questions and address any medical
  they qualify for BasicMed. Visit the main FAQ for more
                                                                  issues or medications taken as they apply to operating an
  details at bit.ly/BasicMedFAQ.
                                                                  aircraft or motor vehicle. Your physician will also conduct a
                                                                  medical examination of the items listed in section 3. These
                                                                  items are similar to what an Aviation Medical Examiner
                                                                  would check for during a third-class medical exam.
                                                                     If your physician is satisfied that you present no medical
                                                                  conditions that would interfere with your ability to safely
                                                                  operate an aircraft, they will complete and sign the form,
                                                                  including their state license number. Legibility is key as you
                                                                  will need this information to print your medical education
                                                                  course completion certificate. Store the completed CMEC
                                                                  in your logbook.
                                                                     If you’re considering BasicMed for the first time, or if
                                                                  perhaps you’ve switched doctors recently and need to get
                                                                  renewed, have a look at the article in our July/August 2017
                                                                  issue titled “Doctor, Doctor, Let Me Give You the News”
    Operations: BasicMed permits flights of any distance or       (spark.adobe.com/page/fjIC3oWxhMgcv). It provides
duration, any time of the day, under visual or instrument         excellent advice for how to approach your doctor about the
flight rules, but there are a few operational limitations:        BasicMed process.
• No more than five passengers, regardless of the number             Finally, remember that to act as PIC under BasicMed, you
   of seats.                                                      must have completed a medical examination in the pre-
• No flying above 18,000 feet mean sea level (MSL) or             ceding 48 months. As I write, I’m days away from my first
   beyond 250 knots (indicated).                                  BasicMed recheck with my doctor — a gentle prod from my
                                                                  BasicMed online course provider was a helpful reminder.
• No flights outside the United States.                           Filling out the CMEC was easy. Just be sure to note any
• No operations for compensation or hire (note: flight            recent conditions (including COVID-19 infections), medi-
   instructors may receive compensation for instructing while     cation changes, and any visits you made to a health profes-
   operating under BasicMed).                                     sional in the last three years. Your doctor should be able to
                                                                  complete and sign the form during your checkup.
The Appointment
Okay, so you’ve established that you, your airplane, and          The Online Course
the types of flying you do are covered under BasicMed.            The final step is completing the BasicMed online medical
Next up is an appointment with a state-licensed physician         course and quiz. There are currently two course provid-
of your choice (preferably one who’s familiar with your           ers (AOPA and the Mayo Clinic), and links to each are
medical history). Before the appointment, you must first          on faa.gov/go/basicmed. The course is required every 24
complete your portion of FAA Form 8700-2, Comprehen-              months to remain covered under BasicMed, but it’s not
                                                                  a bad idea to review the material more often. Once you
                                                                  complete the course, you will be required to enter informa-
                                                                  tion about yourself and the physician who completed the
                                                                  CMEC. You’ll also need to electronically certify that you:
                                                                  • Allow the FAA to access your driving records,
                                                                  • Are being actively treated for any medical condition that
                                                                     affects your ability to fly,
                                                                  • Have completed the CMEC, and

                                                                                                                 January/February 2022 9
hours, which showed an equivalent activity level before and
                                                                                                  after the study period.
                                                                                                     In terms of airmen, the study indicates that BasicMed
                                                                                                  has returned approximately 30,000 airmen to flying status.
                                                                                                  Data also revealed that BasicMed pilots are older than the
                                                                                                  average pilot with a Class III medical (61 years) and are
                                                                                                  much more likely to have required a Special Issuance.
                                                                                                     While this data could suggest that pilots using Basic-
                                                                                                  Med are in a higher category of risk for incapacitation
                                                                                                  and medically-related deaths, that’s not the full picture.
                                                                                                  Notably, the study concluded there was no difference in
                                                                                                  the risk for BasicMed and third-class airmen to have an
                                                                                                  aviation accident. Their report also found no difference
                                                                                                  between these two groups when looking at the accident
                                                                                                  phase of flight, fatal versus non-fatal outcomes, and fatal
                                                                                                  injury autopsy results. It is still early, though, so the FAA
                                                                                                  will continue to monitor trends.
                                                                                                     “BasicMed is a great example of the FAA applying risk-
                                                                                                  based regulation and oversight, shifting responsibility back
                                                                                                  to the pilot,” says FAA Aviation Safety Analyst Brad Zeigler,
                                                                                                  who is also the General Aviation and Commercial Divi-
                                                                                                  sion’s BasicMed program lead. “This responsibility allows
     There are currently two options for the online BasicMed course — AOPA and the Mayo Clinic.
                                                                                                  the pilot to work openly with their physician to objectively
     Links to each are on faa.gov/go/basicmed.                                                    assess medical fitness for flight.”
                                                                                                     In the end, safety depends on the airman to accurately
     • Understand your obligations under 14 CFR section                                           and honestly assess fitness for flight before getting into
       61.53 regarding the operation of an aircraft during a                                      the flight deck, no matter how recent your last checkup
       medical deficiency.                                                                        was (use the IMSAFE checklist). Whether you operate
                                                                                                  under BasicMed, or with an FAA medical, remember that
        When you click submit, this information is transmitted
                                                                                                  14 CFR section 61.53 prohibits you from acting as PIC if
     to the FAA, and you will get a course completion certificate
                                                                                                  you know, or have reason to know, of any medical condi-
     to retain in your logbook.
                                                                                                  tion that would make you unable to operate the aircraft
                                                                                                  in a safe manner.
     A Checkup on BasicMed
                                                                                                     If you have any questions or comments about the
     As part of the FAA Extension, Safety, and Security Act                                       FAA’s BasicMed rule, please contact us at
     of 2016 that created BasicMed, the FAA, in coordination                                      9-AWA-AFS-BasicMed@faa.gov. You can also find answers
     with the National Transportation Safety Board (NTSB), is                                     to frequently asked questions at bit.ly/BasicMedFAQ.
     required to submit a report to Congress that “describes the
     effect of the regulations issued or revised […] and includes                                 Tom Hoffmann is the managing editor of FAA Safety Briefing. He is a commercial pilot and
     statistics with respect to changes in small aircraft activity                                holds an A&P certificate.
     and safety incidents.” In response to this mandate, the FAA
     and NTSB have just completed a report summarizing find-
                                                                                                       LEARN MORE
     ings of the first three years of operations under BasicMed.
        The report considered survey data for airmen, aircraft,
                                                                                                       FAA BasicMed webpage
     and flight operations most closely correlated to operations
                                                                                                       faa.gov/go/basicmed
     conducted under BasicMed, and looked at shifts in accident
     trends in this same general category of operations. So did                                        Advisory Circular 68-1A, BasicMed
     BasicMed lead to more pilots flying more airplanes in this                                        bit.ly/BasicMedAC
     category? Was there any measurable impact on safety?
                                                                                                       Aviation Medical Examiner Guide
        In terms of aircraft, BasicMed did not appear to impact                                        bit.ly/AMEguide
     the number of aircraft most likely to be operated under
     BasicMed. There was modest growth in four years before                                            AOPA BasicMed Eligibility and Renewal Tool
     implementation; numbers subsequently stabilized. There                                            bit.ly/AOPABMRenewal
     was also no measurable impact on the number of flight

10     FAA Safety Briefing
Sm o o t h is Fast
                How to Speed Up Your Medical Certification
                                                                              By James Williams

T
     here is an idiom that says, “Slow is smooth. Smooth         records. Also, make sure your contact information is cur-
     is fast.” The expression was made famous by special         rent in MedXPress.” These tips help any pilot looking for a
     operations soldiers to emphasize that slowing down to       medical, whether for a renewal or an initial application (for
smooth out the process will paradoxically often lead to a        more on what to expect from your first medical exam, see
faster end result. As Tolkien said, “the hasty stroke oft goes   the article “What to Expect From an FAA Medical Exam”
astray.” Both sayings are very relevant to our medical certi-    here: bit.ly/FAAMedExam).
fication. So by rushing the process, you may find yourself
in a far more frustrating ordeal than is necessary. In fact,
the vast majority of medical certificate applications that are
not issued are based on a lack of response from the airman
with the requested information, not a denial by the FAA.
So, in a very real way, taking some time to slow down and
ensure a smooth process could make a huge difference.

Smoothing Out the Process
“There are some very simple things a pilot can do to
streamline the process,” explains Federal Air Surgeon (FAS)
Dr. Susan Northrup. “First, make sure any documents
you submit to the FAA are legible and have your name, a
date, and any identification numbers that you may have
on them.” She continued, “Make sure all letters, including
summaries from physicians, are signed and dated. Ensure
that your package includes all information requested by
the FAA and keep a copy of what you’ve submitted for your

                                                                                                              January/February 2022 11
Guiding Your Path

     Dr. Northrup also has another piece of good advice. “The
     Guide for Aviation Medical Examiners (AME) is a great
     resource for pilots to see what the FAA requires to certify
     a pilot with any given condition.” The Guide for Aviation
     Medical Examiners is the AME’s manual for the medical
     certification of pilots. While the AME Guide was written for        not Special Issuance certificates, that usually come with
     doctors, it is available to anyone online at bit.ly/AMEGuide.       limited durations or additional requirements. These con-
     So if you want to know what your AME is going to be look-           ditions include arthritis, asthma, hypertension, migraines,
                                                                         pre-diabetes, several forms of cancer, and more. For a
          Regardless of what certification path                          complete list of conditions and the applicable worksheets,
          you end up taking, slowing down to                             visit bit.ly/AMECACI.
          ensure a smooth process will likely                            Special Issuance, SODAs, and More
          deliver the best results.                                      If you don’t meet the regular medical standards, there are
                                                                         a few other options. The most common would be a Spe-
     ing for, the guide is a great place to start.                       cial Issuance (SI). Broadly, SIs are performed when a pilot
        “If you have any questions, or need more help, reach out         doesn’t meet the medical standards. Still, through some
     to your AME, Regional Flight Surgeon (RFS), or one of the           alternate means like additional documentation, shorter
     pilot advocacy groups that can provide more information,”           duration certificates, additional monitoring, or other miti-
     said Dr. Northrup. If you have a condition listed in the AME        gations, the FAA can issue an SI so the pilot can fly. Unlike
     guide, you can work with your primary care doctor to make           a CACI, these medical exams must be initially deferred to
     sure that you have current copies of all of the reports and test    the FAA and reviewed by the Aerospace Medical Cer-
     results. It’s also essential to ensure that any tests ordered are   tification Division (AMCD). Under the AME Assisted
     correct, and in the format the FAA needs for certification.         Special Issuance (AASI) program, some SI renewals may
     When in doubt, your doctor may contact your AME or RFS’s
     office. This ensures that you don’t have to repeat tests and
     are ready to be certificated when you walk into your AME’s
     office. But what if you don’t meet the medical standards?

     Meet CACI
     If you haven’t had a medical certificate before or haven’t
     had one in a while, you probably don’t know what a CACI
     is. Conditions AMEs Can Issue (CACI) is a program that
     allows AMEs to issue medical certificates to pilots that
     would usually have to be deferred to the FAA so long as
     they meet specific requirements. That means that you
     walk out of your AME’s office with a medical certificate
     without having to wait for the FAA to review and approve
     your medical. Also, these are regular medical certificates,

12     FAA Safety Briefing
Five Tips to Fast-Track Your Medical                                                   By Dr. Leo Hattrup, FAA Medical Officer

Due to advances in treatment, medical follow-up, and FAA medical programs              Caution: A “Patient After Care Summary” is easily accessible on many
and protocols, the FAA now allows pilots to be issued medical certificates with        Electronic Medical Records, but this DOES NOT contain what the FAA needs to
medical diagnoses and/or medications that were previously considered ground-           make a medical certification decision. The FAA requires a copy of the actual
ing. However, pilots (and the FAA) still want the process to be as fast as possible.   clinical treatment records. Also, the FAA does not need a separate letter or
The key is to come prepared for your Aviation Medical Examiner (AME)                   note from your provider. It is just more work for the provider and usually does
appointment.                                                                           not include all the information that the FAA needs.
In many cases, your AME will have all of the information needed to issue a             3. Help Your Physician Understand Airman Medical Certification
certificate at your appointment. Still, if any item is missing or a question is        There’s a very good chance that the physician who takes great care of you and
unanswered, your medical (if deferred) will take longer. Here are five tips that       your medical conditions has no experience in airman medical certification.
can help speed things along.                                                           Here’s a few things that will help them help you:
1. L ist ALL Your Medical Conditions, Including Any Physician                         • Explain that the FAA makes medical determinations based on the Code of
   Visits Since Your Last Medical                                                        Federal Regulations, which focuses on public safety.
A common mistake that applicants make is not including a complete medical              • Let them know what information the clinical records must contain and that
history on their application. The FAA requires a complete list of your current           an FAA physician may review it.
medical conditions and history, so be sure to make a list of everything,               • Bring a copy of the CACI worksheet for each of your conditions. Let your
including events that happened years ago and those you reported on previous              physician know that you need each item addressed in the clinical records.
applications. This list will also help you fill out your Application for Airman        • If the FAA specifically asks for an evaluation by your physician, make sure the
Medical in MedXPress (Form 8500-8) and give you a starting point to review               clinical records are officially reviewed and signed by your physician and not
what information the FAA will need for each of your conditions. (Remember,               just a clinical extender (e.g., nurse, nurse practitioner, physician assistant, etc.).
the instructions state “Have you ever in your life …”)                                 4. Work With Your AME
Many pilots find it helpful to maintain a list of all doctors visited, including       Unlike most physicians, AMEs are specifically trained by the FAA to know
names, contact information, and specialty, along with the treatment received           when to issue or defer a medical certificate. When a pilot has a condition
and the condition or reason for the visit. Keep in mind that after you have            requiring the AME to defer (such as a heart attack or stroke), your AME can
made an initial report, further reports can be very brief (e.g., “appendectomy,        help you understand which documents the FAA will need to review. Remem-
2003, fully recovered”).                                                               ber, while both your physician and the FAA are concerned about your health,
                                                                                       the FAA also focuses on public safety. For that reason, we sometimes require
2. What Documents Do I Need to Bring to My Appointment?                                testing beyond what is necessary just for patient care.
Take a look at the AME Guide at bit.ly/AMEGuide to find out what documents
and information your AME will need to see for each of your medical conditions at       If you have a condition that requires a Special Issuance, in some cases, your
your appointment. It will also give you a starting point to help you fill out your     AME will be able to issue a follow-up certificate. The FAA has a sub-set (30
MedXPress application.                                                                 conditions, so far, for all classes) for which the AME can issue a renewal of
                                                                                       the Special Issuance. These are called AME Assisted Special Issuances or AASI,
A helpful tip is to use the CTRL-F key search function within the PDF file to find
                                                                                       though the FAA will still review the evaluation. Assuming the evaluation is
requirements for a specific condition. The disposition tables for each condition
                                                                                       favorable, the pilot can walk out of the office with a certificate in hand rather
in the AME Guide will indicate what documents you need to provide. You should
                                                                                       than waiting for the FAA to complete the review. In the past few months, we
see this under the Evaluation Data section of each table. Watch this AME Minute
                                                                                       added a group of the most common cardiac conditions to the list.
video explaining disposition tables at bit.ly/DispositionTables.
Your condition may require your AME to follow the Conditions an AME Can Issue          5. D on’t Forget to Submit Your Information to the FAA Within
(CACI) worksheet, so be familiar with this document. Many pilots find it helpful          14 days of Your Exam
to bring the CACI worksheets or disposition tables to their treating physician(s) to   Due to the volume of documents received by the FAA, if at all possible, send
help them create a note or clinic summary that the FAA can use to make an aero-        your documents within the 14-day window that AMEs are allowed for sub-
medical decision. You can find the CACI worksheets here: bit.ly/CACIWorksheets.        mitting examinations. Also, note whether you or your AME will be sending
                                                                                       in documents, and ensure your AME gets a copy. Advise the FAA of any
If your condition requires you to provide a “current status report,” please note
                                                                                       delay beyond 14 days.
that we are looking for a copy of the detailed clinical progress notes (actual
clinical records) from your treating provider that should address each of the          Approach your medical certification the same way you prepare for a flight. Be
following topics:                                                                      prepared, use a checklist, and have all the tools and supplies that you need on
                                                                                       hand to fast-track your medical to a smooth landing.
•   Diagnosis
•   Treatment and Follow-up Plan
•   Prognosis
•   Specific Items on the Disposition Table

                                                                                                                                                        January/February 2022 13
be handled by selected AMEs without first deferring to the        visit, so there’s no penalty for asking questions before that
     AMCD, assuming specific criteria are met. AASI saves time         process begins. Hopefully, by knowing what to expect
     by not processing on the front end and gets you back to           and being ready with any additional information, you can
     flying status faster. Please see our Jan/Feb 2009 issue for the   reduce a maddening waiting game of frustration to an easy
     article “Getting your Special Issuance Medical” for a more        visit to your AME that ends with a medical certificate in
     detailed look at the SI process. See Learn More for a link.       your hand. Even if that isn’t possible, having that additional
         A Statement of Demonstrated Ability (SODA) is a pro-          information in hand and ready to send to the AMCD
     cess that allows a pilot with a static, non-progressive condi-    should reduce the need for time-consuming back and
     tion that might otherwise be disqualifying to demonstrate         forth. This is where a good AME can make a big difference.
     that they are capable of operating an aircraft safely despite     For more on finding a good AME, see “Building the Right
     the disqualifying condition. The scope for a SODA is more         Team” on page 5 of our Sep/Oct 2018 issue. You’ll find a
     limited than an SI, as the condition must be static but is        link in Learn More.
     valid until the condition changes or is revoked by the FAA.          A smooth and fast certification process is what everyone
     This process may require a special medical test flight (this      wants, and hopefully, this helps you get there.
     might not actually include a flight) to determine that the
     pilot can operate safely and what, if any, limitations must be    James Williams is FAA Safety Briefing’s associate editor and photo editor. He is also a pilot
     placed on the medical certificate. These tests are requested      and ground instructor.
     by the AMCD or RFS and generally carried out by the local
     Flight Standards District Office (FSDO).
         Other means of medical compliance include BasicMed,                LEARN MORE

     Sport Pilot, and aircraft operations that don’t require a
     medical certificate. Each of those categories is an article in         Guide for Aviation Medical Examiners
                                                                            bit.ly/AMEGuide
     its own right, but it’s important to remember that Title 14
     Code of Federal Regulations (14 CFR) section 61.53 still               “What to Expect From an FAA Medical Exam,” FAA Safety Briefing — Nov/Dec
     applies. This means that you must still ensure that you are            2021, p. 6
     fit for flight as pilot in command before each flight.                 bit.ly/FAAMedExam
         Regardless of what certification path you end up taking,
                                                                            CACI Worksheets
     slowing down to ensure a smooth process will likely deliver            bit.ly/AMECACI
     the best results. If you think you may have difficulty with
     the process, check the AME guide to see what the FAA                   “Getting Your Special Issuance Medical,” FAA Safety Briefing — Jan/Feb 2009, p. 2
     needs. This is especially true if you have a CACI condition.           faa.gov/news/safety_briefing/2009/media/JanFeb2009.pdf (PDF)
     Work with your personal doctor and AME to make sure                    “Building the Right Team,” FAA Safety Briefing — Sep/Oct 2018, p. 5
     everything is in hand, and be sure that’s what the FAA                 faa.gov/news/safety_briefing/2018/media/SepOct2018.pdf (PDF)
     needs to see. If you have questions, ask your AME or RFS.
     Also, consider contacting a pilot advocacy group. Many                 SODA Guidance
                                                                            bit.ly/SODAGuidance
     have excellent advice for navigating the process.
         Remember your medical exam doesn’t start until the
     AME pulls up the MedXPress application at your office

14     FAA Safety Briefing
The

                                                                      Human
                                                                      Factor
                                                                      How The FAA’s Medical
                                                                      and Human Factors
                                                                      Research Helps Aviation

                                                                                            By James Williams

W
        hat’s the one thing that runs through all aspects of      And that’s been the challenge. Fatigue is hard to measure
        human endeavor? The human. Whether the human           beyond simply asking the subject directly. It can be hard to
        performs or doesn’t dramatically impacts the           spot the differences between these states or even identify
outcome and safety of virtually everything we do. Paradoxi-    fatigue, even with willing people. If a person is used to only
cally this becomes even more important as systems become       sleeping five to six hours per night, they may not realize they
more automated. A pilot’s human performance is key to a        are operating at a deficit. Because everyone is different and
safe national airspace system (NAS). That’s why the FAA’s      has different sleep needs, and this changes throughout life,
Office of Aerospace Medicine runs research labs focused        diagnosis is a challenge. If someone has become accustomed
on both Human Factors and Medical Research.                    to being fatigued, what they are experiencing is “normal” for
                                                               them, and they are unlikely to mention it to a doctor.
The Fatiguing Nature of Fatigue
Fatigue has been a scourge on every facet of aviation          Defining the Indefinable
from its inception. Whatever role you play in the sys-         The question with a condition like chronic fatigue is how
tem (pilot, maintainer, dispatcher, etc.), fatigue reduces     do you detect it, especially when the person may not even
your performance and creates risk in the system. But           know that their condition is chronic and that they need to
what’s the difference between just being tired and being       report it to a doctor? That’s where a more indirect approach
fatigued? And how could you tell if you are dealing with       may be helpful, and biomarkers can play that role.
acute fatigue or chronic fatigue? Being tired might result        Biomarkers are measurable biological characteristics that
from staying up too late to watch the end of the game,         can serve as indicators of some phenomenon, such as dis-
while acute fatigue might result from a busy week at work.     ease, infection, or environmental exposure. Comparable with
Chronic fatigue is likely the result of an ongoing issue,      measuring the height of a building by observing its shadow
whether professional, medical, or personal. The solutions      and calculating the angle of the sun, biomarkers allow you
to each of these conditions are different so understanding     to detect or measure something that you may not otherwise
the difference between them is critical.                       be able to do. Biomarkers have a variety of applications

                                                                                                              January/February 2022 15
Vicky White loads samples for extraction of genetic material from blood, a   Susan Munster views a pictorial representation of gene expression information,
     first step in the measurement of gene expression biomarkers.                 towards identification of genetic biomarkers related to aviation safety.

     and could be a strong indicator of a condition like chronic                  biomarker can rapidly test drug candidates by rerunning
     fatigue, which lacks a standardized laboratory test. For those               the test before and after exposing the blood sample to those
     suffering from fatigue, having a reliable indicator would be a               drugs. This would allow initial testing of drugs with mini-
     powerful tool for getting treatment. And for those in indus-                 mal risk to any human subject.
     tries like aviation, any kind of objective early warning system                 In 2021, Ohio State University announced the identifica-
     would be invaluable in the number of lives it could save.                    tion of the protein deoxyuridine triphosphate nucleotido-
         Several organizations, including the FAA, have been                      hydrolase (dUTPase) as “a key modulator of the immune
     pursuing this research for some time. In 2015, units of                      response that contributes to the immunological and neuro-
     the National Institutes of Health (NIH) held a conference                    logical abnormalities in some individuals.” It suggests that
     titled Developing Biomarker Arrays Predicting Sleep and                      dUTPase could be used as a biomarker of CFS, at least in a
     Circadian-Coupled Risks to Health. The workshop brought                      subset of patients. Ohio State is also working to develop a
     together many researchers interested in finding biomarkers                   high-volume test that would allow for large-scale screening
     related to sleep. In 2016, a number of Japanese researchers                  and early detection of chronic fatigue.
     published a paper that showed promise in using oxidative                        The FAA has been investigating fatigue biomarkers for
     stress measures to discriminate participants suffering from                  a little over a decade. In particular, the FAA’s Functional
     chronic fatigue from those who were not. But more work                       Genomics Team within the Aerospace Medical Research
     was needed to define this biomarker.                                         Division is seeking molecular biomarkers associated with
                                                                                  cognitive changes during sleep loss. The FAA published
           By working together with industry                                      preliminary candidate biomarkers associated with atten-
           and academia, the FAA hopes                                            tion impairment during sleep loss based on a collab-
                                                                                  orative study with Washington State University. Both
           to make fatigue a much smaller                                         ongoing studies and future planned investigations aim to
           problem in the future.                                                 improve and validate initial findings. Research is a highly
                                                                                  detailed process, and vetting the results is both critical
        In 2019, researchers from Stanford University devel-                      and time-consuming.
     oped a blood test that could accurately identify people                         It’s essential to have as much research from as many
     with Chronic Fatigue Syndrome (CFS). While the study                         angles as possible to develop the best possible metrics.
     was small (40), the test detected the 20 participants with                   Especially with a complex phenomenon such as fatigue that
     chronic fatigue without any false positives. The test works                  has a variety of health and performance implications, hav-
     by measuring the participant’s blood to determine its                        ing more than one approach may improve management or
     immune cell response to stress. The immune cell response                     treatment options. By working together with industry and
     from those participants suffering from chronic fatigue will                  academia, the FAA hopes to make fatigue a much smaller
     be different from those who are not. The hope is that this                   problem in the future.

16     FAA Safety Briefing
You can also read