An Introduction to Cochrane and the Cochrane Library - Mark Wilson, CEO & David Tovey, Editor-in-Chief
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An Introduction to Cochrane
and the Cochrane Library
Mark Wilson, CEO
& David Tovey, Editor-in-Chief
Guidelines International Network/
North America Webinar Series
18th June 2015
Trusted evidence.
Informed decisions.
Better health.
1
Who we are Cochrane is a global independent network of over 36,000 researchers, professionals, patients, carers and people interested in health. We respond to the challenge of making the vast amounts of best available evidence generated through research useful for informing decisions about health. Cochrane is a not-for-profit organization with collaborators from more than 120 countries working together to produce credible, accessible health information that is free from commercial sponsorship and other conflicts of interest.
Our Vision and Mission Our vision is a world of improved health where decisions about health and health care are informed by high quality, relevant and up-to-date synthesized research evidence. Our mission is to promote evidence-informed health decision-making by producing high quality, relevant, accessible systematic reviews and other synthesized research evidence.
Cochrane exists so that healthcare decisions get better. Over the past 22 years, Cochrane has helped to transform the way health decisions are made. We produce reviews that summarize the best available evidence generated through research to inform decisions about health. Our work is recognized as representing an international gold standard for high quality, trusted information. We want to be the leading advocate for evidence-informed health across the world.
Organizational Reach • 36,159 Cochrane contributors – At least a quarter active in last six months • 107 Countries with active authors • Author distribution: • HIC 22,375 • UMIC 4,937 • LMIC/LIC 1,195 • Translation communities actively working in 17 languages
Cochrane’s organizational
structure
Cochrane
Steering
Group
Central Executive Team
16 40 Centres
52 Review Consumers
Methods and 11 Fields
Groups Network
Groups Branches
Reputational Audit showed us that
generally Cochrane and our Reviews are
seen as the ‘gold standard’
Robust methodology
Comprehensive
studies
100% independent
Respected name
International reach
Passionate and
enthusiastic reviewers
… but the Impact of our Reviews is reduced by not concentrating enough on translating them sufficiently into evidence that would be more useful and usable by the wider world
Our Strategy to 2020 has four Goals Goal 1: Producing evidence To produce high quality, relevant, up-to-date systematic reviews and other synthesized research evidence to inform health decision- making.
Some Key Objectives: Goal 1 HIGH-QUALITY: • We will continue to develop and implement comprehensive quality assurance mechanisms for editorial and methodological standards throughout our production and updating processes. RELEVANT: • We will engage with patients and other healthcare consumers, health practitioners, policy-makers, guidelines developers and research funders to identify questions that are most relevant and important to them; and prioritise the production and updating of Cochrane Systematic Reviews accordingly. UP-TO-DATE: • We will ensure that Cochrane Systematic Reviews represent the best evidence currently available by establishing and managing performance against updating targets, particularly for high priority reviews. WIDE COVERAGE: • We will continue to support the production of Cochrane Systematic Reviews across a broad range of questions in order to develop the widest possible body of reliable knowledge about health. PIONEERING METHODS: • We will ensure that established methods are applied consistently and appropriately in Cochrane Systematic Reviews; and continue to develop innovative methods for designing and conducting research evidence synthesis that help us to achieve our mission.
Our Strategy to 2020 has four
Goals
Goal 1: Producing Goal 2: Accessible
evidence evidence
To produce high quality, relevant, up- To make Cochrane evidence
to-date systematic reviews and other accessible and useful to everybody,
synthesized research evidence to everywhere in the world.
inform health decision-making.
Goal 4: Building an effective
Goal 3: Advocating for and sustainable organization
evidence To be a diverse, inclusive and
To make Cochrane the ‘home of transparent international organization
evidence’ to inform health decision- that effectively harnesses the
making, build greater recognition of enthusiasm and skills of our
our work, and become the leading contributors, is guided
advocate for evidence-informed by our principles, governed
health care. accountably, managed efficiently, and
makes optimal use of its resources.Some Key Objectives: Goals 2, 3 & 4
USER-CENTRED DESIGN AND DELIVERY:
• We will put the needs of our users at the heart of our content design and delivery.
• We will consult with our users to develop creative and flexible formats and delivery
solutions for our content that make it more discoverable, accessible, useful and usable
in diverse contexts and settings worldwide.
MULTI-LINGUAL:
• We will translate key content into at least the five other official languages of the WHO …
THE ‘HOME OF EVIDENCE’:
• We will make Cochrane the ‘go-to’ place for evidence to inform health decision-making
by offering a range of evidence-informed products and resources.
GLOBAL ADVOCATE:
• We will advocate for evidence-informed health care and the uptake of synthesized
research evidence in health policy-making and services planning.
GLOBAL PARTNER:
• We will build international and local partnerships and alliances with organisations that
help us to reach people making decisions in health, particularly guidelines developers,
policy-makers, associations of healthcare practitioners and patient organisations.
INCLUSIVE AND OPEN:
• We will establish a membership structure to improve our organizational cohesiveness
and to reduce barriers to participation by creating a clear and open route into the
organisation for people who want to get involved.Selected goals of the Cochrane-GIN partnership • Cochrane Reviews are more aligned with the needs of guidelines developers; • Establish a shared technology platform in which guidelines developers can be aware of and use Cochrane evidence more efficiently, effectively and often; • Improve communication regarding Cochrane Reviews that are out of date or require a more nuanced question; • Support further methodological development for conducting and reporting systematic reviews; • Strengthen advocacy and application of evidence-informed health.
Other key Cochrane partnerships
Find out more about progress on delivering Strategy to 2020 http://www.cochrane.org/strategy2020
We hope that Strategy to 2020 transforms our contribution to Global Health by: Continuing and extending our provision of the highest quality health evidence; Producing user-centred content that meets needs & answers key questions; Opening up Cochrane to the world & engaging with partners in new ways; Diversifying revenues & protecting our financial position; … thereby increasing evidence-informed health decision making around the world.
Trusted evidence. Informed decisions. Better health.
Contents 01 Introduction to the Cochrane Library 02 Cochrane Reviews: how titles are selected and the process 03 Working with guidelines groups 04 Challenges 05 What’s next?
Introduction to the Cochrane Library Databases & additional content in the Cochrane Library Geographical reach & access Licensing arrangements Open access Cochrane Database of Systematic Reviews (CDSR) Impact factor Growth Other metrics
Databases in the Cochrane Library Cochrane Database of Systematic Reviews (8841 records) Central Register of Controlled Trials (861,602 records) Cochrane Methodology Register About the Cochrane Collaboration Database of Abstracts of Reviews of Effectiveness NHS Economic Evaluations Database Health Technology Assessments Database
Editorials
Additional content
Additional content
Derivative products & services
Geographical reach and access
3.66 billion people have free
access in 148 countriesWhere are we now?
Green OA model:
All new and updated
reviews free to access
12 months after
publication
Author retains
copyright
Reviews will be
deposited in PubMed
Central or equivalentWhere are we now?
Green OA model:
All new and updated
reviews will be free to
access 12 months after
Gold OA model: publication
Full OA “author pays” Author retains copyright
model
Reviews will be
Creative Commons deposited in PubMed
licence ie cc-by-nc Central or equivalentWhere are we now?
Green OA model:
All new and updated
reviews will be free to
access 12 months after
Gold OA model: publication
Full OA “author pays” Author retains copyright
model
Reviews will be
Creative Commons deposited in PubMed
licence ie cc-by-nc 903 reviews green OA Central or equivalent
20 reviews gold OA
End 2014The Cochrane Database of Systematic Reviews High quality systematic reviews to inform decision making: • 6000+ reviews • 40 new reviews / 45 updates per month
6.8
Metrics 6.6
6.4
6.2
Impact factor
6
5 year impact
5.8
factor
5.6
5.4
5.2
2010 2011 2012 20136.8
Metrics 6.6
6.4
6.2
Impact factor
6
5 year impact
5.8
factor
5.6
5.4
5.2
2010 2011 2012 2013Metrics
Cochrane Reviews Introduction How titles are selected The editorial process Key components Quality assurance / methodological expectations Updating
Cochrane Reviews Intervention reviews (clinical and non- clinical) Diagnostic Test Accuracy Overviews of reviews Qualitative reviews Soon to come…Prognosis Reviews
How titles are selected From passive to active: transformation Engagement with stakeholders James Lind Alliance priority setting partnerships Guidelines groups Funders Health professionals Patient groups
2015 Priority list 300 + reviews Mainly submitted by CRGs Engagement with research funders and policy makers Dynamic process! http://www.cochrane.org/news/updated-list- cochrane-priority-reviews-now-available
The Cochrane process
• Undertake
search
• Screen
results
• Identify
• PICO
included • Peer
•Define studies review
• Plan search
question •Risk of • Revision
• Describe Editorial
Title •Competence Protocol methods Review bias of • Copy edit
of author included
process
• Peer review • Publish
team studies
• Publish
• Extract
and
analyse
data
• Write up
and submit
UpdatingKey elements of Cochrane Reviews
Key elements of Cochrane Reviews
Quality assurance
Impact
And a little help from our friends
Anti-fibrinolytics in trauma
Avastin for macular degeneration
https://youtu.be/G17R6UXINNcNot always about the big-hitters
Working with guidelines groups Institute of Medicine guidance What do we know already? What’s in it for Cochrane? Recent experiences and learning Our goals
1158 Cochrane Reviews used to inform 238 clinical guidelines: maximum 49 reviews in one guideline (SIGN asthma guideline, number 101 )
Recent experiences
Vitamin A guidelines for WHO
Important to set the parameters
PICOs
Types of studies
Stimulus for the review authors
Timeliness challenges
Unanticipated benefit of having review authors
in the guidelines meetingChallenges for Cochrane Quality management across 52 groups Timeliness and Updating Changing expectations of systematic reviews More sophisticated questions Enhanced methods Different questions The challenge of selective outcomes reporting
What’s next? Investment in technology More efficient production Faster downstream dissemination and impact
Technology and crowds: the “living review” Project Transform 4 elements: Pipeline Getting involved Information exchange New production processes
The “living review”
"How much of what you do
would be different if we
could achieve even a 1 log
(90%) reduction in time to
produce a review or a
review update?”
- Julian ElliottWhat’s next? Expansion of open access Better engagement with stakeholders
Conclusion Exciting time for medical knowledge Goal of impact and use is a major challenge: guidelines are critical Engagement is critical Changing face of evidence
Thank you – any questions?
http://www.cochrane.org/
http://www.cochranelibrary.com/
mwilson@cochrane.org
dtovey@ cochrane.orgYou can also read
