Assessment & management of constipation in cats - Key Long term management - Feline ...

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Assessment & management of constipation in cats - Key Long term management - Feline ...
2021‐04‐12

    Assessment &
    management of
    constipation in cats
    Susan Little, DVM, DABVP (Feline)

                                                                               n
    Bytown Cat Hospital, Ottawa, ON, Canada
    @catvetsusan

                                                                             a
    catvet@vin.com

                                                                u s
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                                                    e t s
                                 a t v
        c
       @               Key
                   assessments
                                                                 Long term
                                                                management
                                              Effective acute
                                                 treatment

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Assessment & management of constipation in cats - Key Long term management - Feline ...
2021‐04‐12

                                           • Infrequent & difficult
                                             evacuation of feces with
         Constipation                        retention in colon & rectum
                                           • Acute & short term or chronic

                          Terminology

                                                                             a n
                                           • Intractable constipation
           Megacolon                       • Poorly responsive to medical

                                                                 s
                                             therapy

                                              t s              u
                                            e
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                         a t v
       c
      @
    Radiographic
    definition of megacolon

    Ratio of colon diameter to L5 length
    • Normal 1.5

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Assessment & management of constipation in cats - Key Long term management - Feline ...
2021‐04‐12

     Functional definition
     of megacolon

     • Acute dilation that responds to therapy

                                                                           n
     • Chronically dilated colon, poorly

                                                                         a
       responsive

                                                                     s
     • Causes?
        • Recurrent constipation, obstipation

                                                                   u
        • Generalized dysfunction of colonic

                                                     s
          smooth muscle

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                                                 e t
                            a t v
        c               Colon motility patterns

       @                Propulsive                 Non‐propulsive

                                                 • Rhythmic
                     • Stimulated by               segmentation that
                       food & activity             mixes contents
                                                 • Absorption of
                                                   water, electrolytes

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Assessment & management of constipation in cats - Key Long term management - Feline ...
2021‐04‐12

                                                                    n
                           The work up

                                                         s        a
                                        t s            u
                                      e
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                     a t v
      c      Look for contributing factors

     @    Drugs                                            Stress

     •   Antacids              Dehydration             • Resource-poor
     •   Opioids                                         environment
     •   Antidepressants                               • Intercat conflict
     •   Diuretics         • Underlying disease        • Changes in routine
     •   Opioids           • Vomiting, diarrhea
     •   Sucralfate        • Impaired mobility, pain

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                                                                                      4
Assessment & management of constipation in cats - Key Long term management - Feline ...
2021‐04‐12

     Chronic kidney
     disease
     • Dehydration
     • Hypokalemia
     • Reduced gastrointestinal

                                            n
       motility

                                          a
     • Phosphate binders

                                         s
     • Amlodipine

                                    t su
                                  e
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                           a t v
        c
       @

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Assessment & management of constipation in cats - Key Long term management - Feline ...
2021‐04‐12

             Everyone’s favourite – the
     01      enema

                                               De-pooping
     02      Manual disimpaction – oh no!
                                                  the cat

                                                        a n
                                                s
     03      There is a better way

                                   t s        u
                                 e
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                a t v
      c                Patient prep

     @
     Correct dehydration                  Anti-emetic
       & hypokalemia                       Analgesic

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Assessment & management of constipation in cats - Key Long term management - Feline ...
2021‐04‐12

                               Warm!
                            Water, saline,
                             lactulose

       5-10 mL/kg

                                      a n
                         u s
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                    e t s
               a t v
      c
     @
     #EnemaFail

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Assessment & management of constipation in cats - Key Long term management - Feline ...
2021‐04‐12

                Manual disimpaction
     (why is it always when you’re ready to leave??)

                                               a n
                                      u s
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                           e t s
                a t v
      c
     @

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Assessment & management of constipation in cats - Key Long term management - Feline ...
2021‐04‐12

     A better way!

                                                        a n
                                                     u s
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                                                e t s
                             a t v
        c
       @
     Laxative trickle-feeding
                   Dr. Tony Carr
      Western College of Veterinary Medicine,
           University of Saskatchewan

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Assessment & management of constipation in cats - Key Long term management - Feline ...
2021‐04‐12

                    Colonoscopy or laxative solution
                    intended for acute treatment

                            Polyethylene glycol 3350
                            (macrogol)

                            Sodium bicarbonate
                            sodium chloride

                                                          n
                            potassium chloride

                                                        a
                            Brand names:

                                       s
                            Golytely, Colyte, Movicol

                       t s           u
                     e
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       a t v
      c
     @
          6‐10 mL/kg/hour

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                                                                     10
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                 Defecation in median 8 hours
                            (range 6-14)
                     Median total dose 80 mL/kg

                                         a n
                                  u s
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                        e t s
              a t v
       c
      @
     Pre-treatment

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          8 hours later

                            a n
                      u s
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               e t s
       a t v
      c
     @                  Everybody
                       poops better
                         at home!

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                                             12
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          Pre-treatment

                                                              a n
                                                          u s
                                  t s
      Hannah Vds, Facebook Feline Veterinary Medicine Group

                                e
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       a t v
      c
     @

      Hannah Vds, Facebook Feline Veterinary Medicine Group

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                                                                                     a n
                                                                        s
                                                    7 hours later

                                              t s                     u
                  Hannah Vds, Facebook Feline Veterinary Medicine Group

                                            e
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                  a t v
      c           Long term management

     @
     Identify &
      manage
     concurrent
      diseases
                            Hydration                  Dietary
                                                       therapy
                                                                          Prokinetics,
                                                                           laxatives

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                                                                                                  14
2021‐04‐12

         Hydration
     •   Wet food
     •   Flavoured water
     •   Bottled/filtered water

                                                                                        n
     •   More water bowls
     •   Subcutaneous fluids if appropriate

                                                                       s              a
                                                     t s             u
                                                   e
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                              a t v
             c                     Dietary therapy

            @
         Type of diet

         Low residue

         Increased fiber
                            Characteristics
                            Highly digestible
                            Decreased fecal bulk

                            Soluble & insoluble fiber:
                            • Increased fecal bulk & water
                                                                Examples

                                                                • Hill’s Prescription Diet i/d Feline

                                                                • Royal Canin Feline
                                                                  Gastrointestinal Fiber Response
                                                                • Hill’s Prescription Diet w/d
                                                                  Feline or r/d Feline
                            Soluble & insoluble fibre:
                            • Increased fecal bulk & water
                            Specific prebiotics:
         Modulation of                                          • Hill’s Gastrointestinal Biome
                            • Increased postbiotics that
         microbiome           improve motility, provide energy,
                                                                  Digestive/Fiber Care
                              anti-oxidant & anti-
                              inflammatory effects

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        When dietary therapy isn’t enough

           01       Add a laxative        02      Add a drug

                                                                              n
                • Lactulose                    • Cisapride
                • PEG3350 (macrogol)           • Metabolized in liver

                                                                            a
                without electrolytes           by cytochrome P450

                                                         u s
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                                         e t s
                             a t v
      c
     Top tips for managing constipated cats

     @          Identify
      Underlying factors,
     concurrent diseases

      Evaluate
                                     A     D
                                                          Provide
                                                          Effective acute
                                                          management

                                                                Recommend
      Hydration,
     electrolytes
                             B                      E           Dietary therapy for
                                                                long term
                                                                management

           Radiograph                                     Add
          GI obstruction,
           masses, pelvic
                                     C     F              Laxatives, drugs if
                                                          needed
      fracture, colon size

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                                   a n
                      u s
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            e t s
       a t v
      c
     @
                catvet@vin.com

               @catvetsusan
               @purrpodcast
               purrpodcast.net
                bit.ly/CatBites

               drsusanlittle.net

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