BIG IDEAS SHOWCASE 2013 - new technologies for world markets an Enterprise Ireland initiative

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BIG IDEAS SHOWCASE 2013 - new technologies for world markets an Enterprise Ireland initiative
BIG IDEAS
              SHOWCASE 2013
              new technologies for world markets
              an Enterprise Ireland initiative

25th September, Aviva Stadium
BIG IDEAS SHOWCASE 2013 - new technologies for world markets an Enterprise Ireland initiative
www.enterprise-ireland.com/bigideas
BIG IDEAS SHOWCASE 2013 - new technologies for world markets an Enterprise Ireland initiative
Minister’s foreword
Seán Sherlock TD
Minister for Research & Innovation

Through consistent and considerable             and commercialisation of innovative new
public and private investment in science,       products and services and increase the
technology and innovation over the last         number of new technology-based start-
decade, we now have a strong base of            up companies and ultimately help create
research expertise within Ireland. With this    the jobs we need. In order to benefit from
in mind, the Action Plan for Jobs focuses       our publicly funded research, we need to
on research and innovation as a tool to         set ambitious targets – nationally and at
build our economy and boost job creation.       EU level – to ensure that we maximize the
By implementing and commercialising this        availability of productive, job creating funds
research we can create a stronger, more         for Irish researchers. We know from our
sustainable economy.                            own enterprise sector that research and
                                                development drives exports and profitability
The Big Ideas Showcase illustrates the
                                                and helps to secure and grow jobs.
quality of research happening in Universities
and Institutes of Technology across the         The Big Ideas Showcase 2013 provides
country. It demonstrates the success of         the perfect platform for researchers in
Ireland’s national technology transfer system   the areas of ICT, Lifesciences & Food and
and exhibits the high standard of research      Manufacturing, Engineering & Energy with
that this country is producing. Steps are       the opportunity to meet the investors
underway to bring together a lot of existing    and business partners that will assist in
research activity and involve the enterprise    transforming their publicly funded research
sector more directly in this research.          into the commercial products and services
Specifically, the Technology Centres being      of the future.
progressed by Enterprise Ireland and IDA
                                                The Big Ideas you hear about today are the
which will play a key role in positioning
                                                culmination of a process that is funding
Ireland as a recognised centre for applied
                                                research and commercialisation and
research, supporting the attractiveness
                                                which has at its core the aim to support
of the State as a location for foreign
                                                entrepreneurs and attract investment and
direct investment and the growth of Irish
                                                investors. Ultimately, this process boosts
industry. These Centres work well with and
                                                job creation, supports industry, encourages
complement research funded by Science
                                                overseas investment into Ireland and has
Foundation Ireland and other publicly -
                                                an extremely positive effect on the overall
funded R&D that is happening in Ireland.
                                                economy.
This Government is dedicated to supporting
                                                I would like to commend Enterprise Ireland
the transfer of ideas and knowledge created
                                                on the success of this annual event. I would
in our Higher Education Institutes into Irish
                                                also like to congratulate the researchers
industry – turning good ideas into good
                                                participating in the Big Ideas Showcase this
jobs.
                                                year. I wish you all every success.
As announced in June 2013, €21million
in funding has been allocated to the
Enterprise Ireland Commercialisation
Fund. This will accelerate the development

                                                                             2013                1
BIG IDEAS SHOWCASE 2013 - new technologies for world markets an Enterprise Ireland initiative
BIG IDEAS SHOWCASE 2013 - new technologies for world markets an Enterprise Ireland initiative
A word of welcome
to investors
Gearóid Mooney,
Divisional Manager Research and Innovation

On behalf of Enterprise Ireland, I would         Enterprise Ireland can help your company
like to welcome you to our annual Big            connect with this wealth of talent and
Ideas Technology Showcase - the key event        investigate the potential for funding
in the Irish research commercialisation          support. This is allocated in three ways:
calendar.
                                                 Enterprise Ireland’s Innovation Vouchers
There will be 21 new investor-ready              Initiative allows SMEs and micro businesses
technologies showcased today and                 to commission a small piece of research
the market quality of the opportunities          with a €5,000 voucher redeemable in the
on display is a reflection of the                Higher Education Research System. Since
commercialisation work that is ongoing           2009, over 3,700 Innovation Vouchers have
in Higher Education Institutes throughout        been allocated. This initiative helps smaller
Ireland. This year’s “Big Ideas” cover           companies solve a business problem or take
numerous market segments including               the first steps into R&D.
software, heathcare, fashion, cleantech and
                                                 Another initiative is the Innovation
homeware.
                                                 Partnership Programme which is tailored
Enterprise Ireland is responsible for            to support collaborative projects between
the development and growth of Irish              companies and research teams. There have
enterprises in world markets. A key aspect       been over 200 companies successfully
of achieving this duty is to optimise the flow   involved in Innovation Partnerships over the
of commercial opportunities arising from         last four years and more than 1000 in the
the Irish government’s investment in our         past decade.
national research system.
                                                 Enterprise Ireland also support companies
Evidence of the impacts of research              that want to get involved in leading the
commercialisation can be seen in the Irish       research agenda in their industry through
economy, specifically the 110 spin outs          our Technology Centre programme.
that have emerged from commercialised            Technology Centres, a joint venture
research since 2009. Enterprise Ireland          between Enterprise Ireland and IDA Ireland
helps researchers at all stages of the           are collaborative research centres that
commercialisation pipeline through our           are led by industry. Currently, there are 12
Commercialisation Fund with over 400             established Technology Centres with three
commercialisation projects funded in the         more in the pipeline. These centres work to
last four years.                                 an agenda agreed by a consortium of Irish
                                                 SME’s and multinationals based in Ireland
Existing Irish companies also benefit from
                                                 which share common research goals.
direct access to technologically advanced
researchers who are focused, efficient and       The work presented here at Big Ideas
eager to collaborate with industry. This is      Showcase 2013 demonstrates the level of
an impressive national resource consisting       commercial innovation that is nascent in our
of more than 4,500 researchers backed by         publicly funded research institutes. I invite
Government funding.                              you to engage with the participants, expand
                                                 your knowledge of the great potential of
                                                 these innovations and hopefully identify the
                                                 ideas that best suit your investment and
                                                 support.

                                                                             2013                3
BIG IDEAS SHOWCASE 2013 - new technologies for world markets an Enterprise Ireland initiative
Big Ideas schedule overview
    09:00		    Registration
    10:00		    Official Opening and Presentation of Commercialisation
    		         Awards by Seán Sherlock TD, Minister for Research & Innovation
    10:10		    Opening Address by Gearoid Mooney, Divisional
    		         Manager Research & Innovation, Enterprise Ireland
    10:20		    Innovation and Research Expo
    10:45		    Big Ideas Technology pitch session 1
    13:00		    Lunch
    14:00		    Big Ideas Technology pitch session 2
    16:30		    Event Ends
    16:45		    Evening reception

    Big Ideas Technology Pitch Session Schedule
    Time		Presenter			Big Idea
    10:45		    Xuemei Germaine		           MicroGen Biotech
    11:00		Wayne Allen			Embo Medical
    11:15		    Hillary Kenna 		            Vizolve Ltd
    11:30		Ken Byrne			GRASP
    11:45		    Liam Mullins			             Lumen on Demand
    12:00		Julia O’Rourke			Rempad
    12:15		Wayne Byrne			OxyMem
    12:30		Garret Ryan			Crescent System
    12:45		Kevin McCarthy		Aficionado

    Lunch
    14:00		    Ronan Clarke			             Smart Wall Paint
    14:15		Paul Leonard			DiCast
    14:30		Kevin Doherty			Gazel
    14:45		    Miguel Ponce de Leon        Mobile Cloud Alliance
    15:00		Edward Grant			Cipherdocs
    15:15		    John Tinsley			             Iconic Translator Machines
    15:30		Mark Bruzzi			Vetex Project
    15:45		Mark Hughes			Style-Eyes
    16:00		    Eamon Murphy		              MR Gum Technology
    16:15		Pat Hobbert			Vasgard
    16:30		Kevin Koidl			Wripl
    16:45		Deirdre Hogan		Ata-Bot

4             2013
BIG IDEAS SHOWCASE 2013 - new technologies for world markets an Enterprise Ireland initiative
Today’s chairperson
John Lynch

John Lynch is a strategic business         knowledge. As well as working with
thinker with strong analytical skills to   a range of start-up and early stage
direct and drive business growth and       companies, he was CEO of Merrion
profitability. John has an impressive      Pharmaceuticals plc, where he worked
track record of leading growth             from start up in 2004 until 2007. Until
businesses and also of attracting          2007, he also held senior positions in
and building experienced senior            a number of countries with Abbott
teams, including building a business       Laboratories between 1989 and 2003.
from the ground through IPO. John          He served on the Irish Government’s
successfully completed several rounds      Innovation Taskforce in 2009/10.
of equity fundraising , negotiated
                                           Self motivated and dynamic, John
major contracts, Government price
                                           is continuously seeking ways to
negotiations and influenced health
                                           improve both business and personal
policy. John is experienced in out-
                                           performance and add-value. He has a
licensing and acquisition, in-license of
                                           huge interest in new technology and
products and the generation of new
                                           building strategies and routes to bring
product ideas.
                                           it to market. He has worked with a
John has worked extensively in the         number of the presenters in the Big
life sciences industry both in Ireland,    Ideas Showcase, aiding them to bring
the USA, UK and internationally for        their technologies towards the market.
the past 25 years. Over that time he
                                           John’s advice to technology
has assumed many roles which have
                                           innovators is to ensure that the four
had a strong emphasis on innovation
                                           main foundations of any start-up
and new product development - these
                                           - innovative technology with clear
include CEO, Non-Executive Director,
                                           Intellectual Property Rights, a validated
consultant, mentor, International
                                           and viable market accompanied by a
Business Development Director and
                                           strong business model and a strong
Commercial Director. He has also
                                           entrepreneurial team. These are all
worked in new product development,
                                           part of the innovation process from
operations, finance and sales &
                                           the start and move forward in parallel.
marketing. Through his extensive
                                           Get the best team around the table to
work with both start-up businesses
                                           work on your idea as soon as you can,
and large multinationals, he has
                                           and a great idea could become a great
experienced a very broad range of
                                           company.
life sciences technology areas such
as drug delivery, drug development,
medical devices, medical diagnostics
and medical nutrition. This has giving
him a great breadth of industry

                                                                              2013     5
BIG IDEAS SHOWCASE 2013 - new technologies for world markets an Enterprise Ireland initiative
BIG IDEAS SHOWCASE 2013 - new technologies for world markets an Enterprise Ireland initiative
Meet this year’s presenters
Dr. Xuemei Germaine MicroGen Biotech Ltd             8

Wayne Allen Embo Medical                             9

Hilary Kenna Vizolve Ltd                             11

Ken Byrne CEO Grasp Wearable Technologies           12

Liam Mullins Lumen-on-Demand                        13

Julia O’Rourke REMPAD                               15

Wayne Byrne OxyMem                                  17

Dr. Garrett Ryan Crescent System                    18

Kevin McCarthy Aficionado                           19

Ronan Clarke Smart Wall Paint                       20

Dr. Paul Leonard Innovamab                          21

Kevin Doherty Gazel                                 23

Miguel Ponce De Leon Web Real Time Communications   24

Ed Grant CipherDocs                                 25

Dr. John Tinsley Iconic Translation Machines        26

Dr. Mark Bruzzi Vetex                               27

Dr. Mark Hughes Style-Eyes                          29

Eamon Murphy MR Gum Innovation                      31

Pat Hobbert Vasgard                                 32

Dr. Kevin Koidl WRIPL                               33

Dr. Deirdre Hogan Ata-Bot                           34

                                                    2013   7
BIG IDEAS SHOWCASE 2013 - new technologies for world markets an Enterprise Ireland initiative
MicroGen Biotech Ltd
                               Dr. Xuemei Germaine

                               Environmental
                               clean-up solutions

    Contamination of urban environments        One Stop Biotech Solutions
    and water sources is a worldwide issue.
    It severely affects our eco-system         MicroGen Biotech’s ready-for-market
    functions and human health. MicroGen       products and platform technologies
    Biotech Ltd is a bioremediation            include site-specific microbial products,
    company based in Ireland which has         EcoPileTM technology, Plant-Microbe
    developed a number of environmentally      technology and Bioremediation-Biofuel
    friendly clean-up solutions. We use        technology. Providing innovative, clean,
    natural novel bacteria and plants to       bioremediation solutions for the clean
    clean up toxic environmental pollutants    up of large scale contaminated sites
    from soils and water streams.              is key for the success of the company
                                               which was spun out of IT Carlow. Dr.
    The goal is to provide complete clean up   Germaine indicates the “initial target
    solutions for problem sites using unique   market for this technology is China
    combinations of natural soil degrading     and we are actively seeking to secure
    bacteria and site specific organisms,      investment to accelerate our growth”.
    coupled with novel engineering and
    treatment processes. MicroGen Biotech’s
    solutions are natural, site specific and
    highly cost effective.

    Notes

8              2013
Embo Medical
Wayne Allen

Safe, cost effective
embolisation

Embolisation is a procedure to shut         Next generation of embolisation
down blood flow in a diseased vessel
or to a diseased organ, for example         Their product, the Caterpillar is a one-
embolisation can be used to                 shot embolisation device, that embolises
stop blood flow to a tumour.                a vessel with just one implant and takes
                                            just five minutes in total to deploy. The
Worldwide, there are approximately          Caterpillar has inbuilt anti-migration
200,000 procedures done each year.          features to ensure that only the intended
Current practice is to use multiple coils   vessel is blocked by the procedure.
(about the width of a strand of hair)
to shut down the vessel, requiring          The development team, Colin Forde and
an average of nine coils in any one         Wayne Allen, who have over 25 years
procedure. There are two key issues with    of medical device industry experience,
the use of coils:                           took part in the Bioinnovate Ireland
                                            programme, which allowed them to
1. the coils can migrate away from the      become a “fly-on-the-wall” in medical
   target vessel causing unintended         procedures over a three month period.
   blockages elsewhere in the body          Having witnessed several embolisation
2. it takes five minutes to implant each    procedures, they realised that current
   coil, resulting in 45 minutes of a       technology could be greatly improved,
   physicians time to put in the coils      with the effect of improving patient
   alone.                                   safety, reducing procedural time and
                                            therefore cost to the healthcare system.
                                            After 18 months researching the
                                            problem at NUI Galway, the product was
                                            developed and has already undergone
                                            successful animal studies. The team
                                            objective is to “make the Caterpillar the
                                            market leading peripheral embolisation
                                            device, and is currently fund-raising to
                                            bring the technology through regulatory
                                            approval to commercialisation” explains
                                            Wayne.

Notes

                                                                               2013     9
Vizolve Ltd
Hilary Kenna

visualising search for
education, research
and libraries

Based out of the Media Cube in IADT          ‘One query, one screen and all
Dún Laoghaire, Vizolve have developed        the answers’
a personalised search and discovery
application called SeeSearch.                Search behaviour has not evolved:
                                             users simply keep retyping new queries
SeeSearch is initially focusing on the       to refine their searches rather than
education, research and library sector.      laboriously clicking through pages
The technology searches through              of results. SeeSearch changes all of
everything the college or library owns;      that because it is very different to the
books, e-books, databases, e-journals,       traditional text-based results we are
dvds, multimedia repositories, etc – as      all accustomed to seeing on search
well as content available on the web,        engines.
and can be personalised to suit your
interests. SeeSearch provides a single       The SeeSearch display is very visual
place to search all of your content          and gives hundreds of times more
resources, making it possible to find        results in a single screen, but in a very
resources from multiple sources with         understandable and structured way,
one search, instead of having to search      meaning you are much less likely to
several databases individually.              need to keep searching over and over
                                             again, and more likely to find what
Not only does SeeSearch find the most        you want thereby increasing search
relevant search results, it also presents    productivity. SeeSearch presents an
them in a new and exciting way through       easy-to-use visual search experience
visualisation. When you search through       that gives you much more results in a
any of the current search engines you        single screen, and it’s available on your
get a text based list, most people don’t     desktop, tablet and mobile.
go beyond the first or second page of
the results. With SeeSearch you get a        Currently integrated with hundreds of
visualisation of your search results, this   thousands of books, media and article
means that instead of seeing text-based      content, the technology is a horizontal
results you see a visual representation      solution and has applications across a
of the book and DVD covers etc. You          number of areas including e-commerce,
also see graphical representations of the    travel and enterprise search. So for
areas your results are coming from.          anyone interested in web and mobile
                                             technologies, content and big data
                                             access and the general discovery space,
                                             SeeSearch will ‘give you all the answers’.
                                             For more information please visit
                                             www.vizolve.com

Notes

                                                                                  2013    11
Grasp Wearable Technologies
                                  Ken Byrne CEO

                                  Real-time movement
                                  and physiological
                                  measurement

     Grasp Wearable Technologies is an            One of the key advantages of the Grasp
     emerging technology design services          Run system is that the measures can
     and product development company.             be taken outside an instrumental lab
     Grasp creates wearable products for the      setting. The system is comprised of a
     consumer market which addresses real         small lightweight device attached to
     world problems in fitness, sports, health    each shoe coupled with a wrist-based
     and consumer electronics in the fast         device for real-time feedback to the user
     growing wearable technology market.          while running.
     The company is developing novel              Smartphone and tablet/ web apps
     applications of its technology to            complete the user experience and
     measure complex human movement and           provide the user with flexibility on
     physiological characteristics through        usage modes, personalisation
     wearable products and systems.               options and presents comprehensive
                                                  information. One of the distinguishing
                                                  elements of this product is that it
     Flagship Product -                           supports runners at all levels providing
     Grasp Run System                             the user with the most appropriate
                                                  measures and feedback for their abilities
     Grasp aim to provide helpful, user           and aligned with their personal goals.
     friendly and engaging products for           The system has been developed in
     use in everyday settings.                    collaboration with athletes, sports
     The first of their products is the Grasp     therapists and healthcare professionals.
     Run System which provides users with         “Our objective is to secure investment
     useful information on the biomechanical      to build out the company, our flagship
     and physiological characteristics of their   products and our go to market
     running style.                               strategy.”, explains Ken

     Notes

12               2013
Lumen-on-Demand
Liam Mullins

Faster Safer Intervention

The Lumen-on-Demand technology is             Opening a channel
designed to reduce the procedural time
of interventional surgeries which require     Lumen-on-Demand provides a channel
the use of a catheter.                        (or lumen) in the catheter that can
                                              deliver fluid into the patient without
The new “Lumen-on-Demand” feature             having to exchange the catheter or
is a smart add-on to catheters and            guidewire. The channel is concealed
there are a number of benefits in             until the physician injects fluid into the
doing this such as improved safety,           channel. The channel expands only on
through reduced radiation exposure            demand ensuring catheter performance
to the physician and patient, and             is uncompromised during delivery,
increased cost effectiveness achieved         navigation, and removal.
by decreasing procedural time (approx.        Developed in NUI Galway, the
€1,000 per hour). Additionally the            technology can be applied to any clinical
volume of contrast fluid (which can be        area in the endovascular space, and to
toxic) required to navigate and monitor       over 1 million procedures annually.
the catheter may be reduced.
                                              “Our objective is to identify a co-
The team behind Lumen-on-Demand               development partner to bring this
spent 3 months observing cathether            technology to the clinic where it can
based procedures and discovered that          reduce procedural cost and improve the
there are a number of time consuming          safety of procedures.” explains Liam.
actions that are constantly repeated,
such as removing and re-inserting
guide wires from catethers. Based on
these observations the team identified
a need to streamline procedures by
eliminating the requirement to remove
the guidewire for contrast fluid injection,
and have developed the Lumen-on-
demand technology to meet this need.

Notes

                                                                                   2013    13
BIG IDEAS
           SHOWCASE 2013
           new technologies for world markets
           an Enterprise Ireland initiative

Enterprise Ireland presents the first ever
Technology Centre Forum.

Technology Centres are collaborative
entities established and led by industry.
They are resourced by highly qualified
researchers associated with research
institutions who are empowered to
undertake market focussed strategic R&D
for the benefit of all industries.

Come and see our exhibition and hear from
companies like yours who have benefited
from the Technology Centre Programme

For more information please visit www.
enterprise-ireland.com/techcentreforum

                                              2013   14
REMPAD
Julia O’Rourke

Next generation
reminiscence therapy

Dementia is a growing problem both in       The REMPAD system incorporates
Ireland and globally. Current projections   content management tools and training
indicate that there will be a significant   to provide a fully automated solution
increase in the number of people with       that utilises online data archives to
dementia in Ireland, from approximately     provide a clinical support tool. This
40,000 at present to 100,000 by             benefits nursing home residents and
2036. Globally 4.6 million people are       their carers. REMPAD is deployed to
diagnosed with dementia each year. 30%      nursing homes as a Web App and
of those will reside in nursing homes for   utilises existing wi-fi infrastructure within
the last years of life.                     care homes.
With no cure for dementia and the           “REMPAD reduces overhead and
failing of pharmacological interventions    resource costs for care homes whilst
to address this problem, healthcare has     improving social connection amongst
focused on enhancing Quality of Life.       residents and staff”.
Reminiscence therapy is a validated,
evidence based approach which has
been found to improve nursing home          Advantages
residents mood and wellbeing and also
have a positive impact on cognition         REMPAD has been successfully trialled in
and communication.                          nursing homes with residents suffering
                                            from dementia where it has been found
                                            to maintain wellness and improve mood
                                            through social interaction.
The Next Generation of
Reminiscence Therapy                        “We have a pipeline of customers
                                            waiting for REMPAD to come on the
REMPAD, a novel connected-care              market” says Julia O’Rourke, “We are
solution emerging from research carried     looking for investment to bring this
out in DCU, delivers next generation        valuable a much needed resource to
reminiscence therapy as part of             them”.
person-centered care in nursing
homes for residents with dementia.

Notes

                                                                                  2013      15
16   2013
OxyMem
Wayne Byrne

Changing the economics
of wastewater treatment

Activated Sludge has been the               Bubble-less aeration
cornerstone of wastewater treatment for
the last 100 years. This is a very energy   Researchers at UCD have developed
intensive process due to the requirement    OxyMem which does not rely on a
to provide oxygen, via aeration, to the     bubble to transfer oxygen, instead
pollution degrading microorganisms          OxyMem uses gas permeable
so it can be discharged back to the         membranes, that allow oxygen to be
environment.Typically 2.5 percent of a      transferred directly to the wastewater
developed nation’s electricity (US, UK,     treating bacteria. OxyMem is capable of
Ireland) is used for the treatment of       achieving up to 100% oxygen transfer
wastewater and aeration accounts for        efficiency, as no oxygen is lost to the
60% of this demand. The reason the          atmosphere. The results are a four fold
demand is so high, is that large volumes    saving on energy costs when compared
of air (21% oxygen) must be forced down     to forced aeration.
to the bottom of deep tanks to create       In addition to the energy benefits,
bubbles. The bubbles then travel to the     OxyMem’s patented system uses fewer
surface and during the short journey        chemicals, has lower pumping costs,
transfer some of the oxygen to the water    is built on a reduced physical footprint
where it is available to be used by the     and has the added benefit of being fully
microorganisms. Once at the surface         automated.
the air bubbles escapes back to the
                                            The system comprises a turnkey aeration
atmosphere resulting in a loss of 60-70%
                                            system for the wastewater market which
of the potential oxygen.
                                            has been valued at 4 billion euro and is
                                            expected to grow to over 6.5 billion euro
                                            in the near future. OxyMem is the first to
                                            deliver this technology at a commercial
                                            scale and has a full size unit on test at
                                            Severn Trent’s Minworth site, the second
                                            largest water treatment plant in the UK.
                                            “Our objective is to secure a €3 million
                                            Euro investment to fully develop our
                                            manufacturing/extrusion capability” says
                                            Wayne.

Notes

                                                                                2013     17
Crescent System
                                 Dr. Garrett Ryan

                                 Hypertension – a nerve
                                 knockout solution

     Hypertension, or high blood pressure,       Garrett and his team have developed a
     is a significant problem in the modern      novel drug delivery system; the Needle
     world affecting large proportions of        Catheter System delivers drugs safely
     the world’s ageing population. Many of      and effectively to a target location, at a
     those affected can control the condition    specific depth where the drug diffuses
     using a cocktail of drugs but there is a    around the artery. This procedure
     significant proportion who are resistant    results in minimal damage to the vessel
     to current pharmaceutical therapies.        wall, reducing the risk of late stage
                                                 complications.
     Clinicians have shown that by destroying
     the nerves within the wall of the renal
     artery, they can succesfully lower
     blood pressure in patients resistant to     Advantages
     medication. The majority of devices         Renal denervation is predicted to
     in development use energy based             be a game changer in the treatment
     systems to destroy the nerves (known as     of hypertension, as well as potential
     sympathetic nerves) by burning through      indications such as sleep apnea, chronic
     the artery wall. While all have shown       heart and kidney failure and diabetes.
     efficacy in the form of reduced blood       This drug delivery solution should
     pressure, there is the potential for long   represent a more cost effective solution
     term damage to the inner surface of the     to energy based systems being sold in
     artery.                                     the market at present.
                                                 “Our objective is to secure investment
                                                 that will facilitate the creation of a start-
     Finding a cure for resistant                up company dedicated to bringing the
     hypertension                                Crescent System to market.”, says Dr.
     The Chemical Renal Denervation project,     Ryan.
     emerging from research carried out at
     Trinity College Dublin and NUI Galway,
     has developed an alternative solution to
     target the sympathetic nerves.

     Notes

18               2013
Aficionado
Kevin McCarthy

Online management of
organisational expertise & skills

Large multinational corporations with        Somewhat comparable to Linkedin,
thousands of employees over multiple         Aficionado is distinct in that expert
geographical locations, by the nature of     doesn’t need to regularly update their
their scale and disparate locations, have    profile with recent work.
difficulty in keeping track of what teams
                                             The expert profile is built automatically
are doing in other locations and which
                                             and this was deliberate because people
experts are on which teams etc.
                                             generally only update their information
                                             sporadically meaning the data decays
Aficionado is a platform for the location
                                             and becomes less useful very quickly.
of expertise, and management of
expertise, across an organisation. This      Initially, the prototype was developed
technology can be used internally within     for the research market. Aficionado was
an organisation from an administration       able to tap into the wealth of document
or HR point-of-view, but it can also be      repositories in seven Irish institutions,
used externally to showcase expertise        use publication outputs to build rich
and skills.                                  profiles of researchers. People can
                                             search for particular experts or skillsets
Expert engagement and                        across all universities in Ireland.
management                                   Aficionado has potential in a wide
This Cloud-based software solution uses      variety of sectors such as government,
document repositories or other streams       pharma, banking & finance and
of information, such as internal social      professional consulting firms and
networks or Twitter streams to build an      the professional recruiting market.
expert profile of the individuals and then   “We have come to Big Ideas to talk to
hang search and discovery services off       interested investors regarding seed
the profiles.                                funding for our business” explains Kevin.

Notes

                                                                                  2013    19
Smart Wall Paint
                                 Ronan Clarke

                                 Whiteboards with a
                                 difference

     Smart Wall Paint is a breakthrough          Rapid Growth
     concept – a novel paint that when
     applied to any smooth surface,              Smart Wall Paint Ltd was established
     transforms it to a wipe-on/wipe-            by Ronan Clarke in 2012 and already
     off whiteboard surface. Smart Wall          has a significant presence in Ireland,
     Paint is working with CREST ( Centre        UK, Europe, Australia and Canada.
     for Research in Engineering Surface         The company is growing rapidly with
     Technology) at DIT through the              its workforce of six set to double in
     Innovation Partnership programme            the coming months. In addition to its
     and is developing generation three of       five English language ecommerce sites,
     its product range, which I will bring a     Smart Wall Paint will launch Italian,
     unique new product to the market in         German and French language sites
     2014. Smart Wall Paint is used primarily    in September.
     by Business and Educators to change         Roughly 90% of the product is exported
     the way they the communicate and            through both online and channel
     collaborate.                                partners such as large stationery
     Smart Wall Paint is already in production   companies. Smart Wall Paint is also
     and selling globally. Customers already     represented through distributors in UK,
     using Smart Wall Paint include large        Hong Kong, Dubai and Singapore with
     and small businesses, schools and           this route to market set to increase
     universities such as Google, Twitter,       significantly throughout 2014.
     Facebook, Marks & Spencer, Tesco,           “Smart Wall Paint changes the way
     Microsoft, Trinity College, Glenstal        people work together by turning
     Abbey and hundreds more all over the        ordinary rooms and walls into working
     world.                                      spaces that help people engage,
                                                 collaborate and create.”

     Notes

20               2013
Innovamab
Dr. Paul Leonard

Innovation in monoclonal
antibody discovery

Pharmaceutical and biotechnology           with a unique effect and the potential
companies are continuously looking         to create the next blockbuster drug.
for new cutting edge technologies to       Researchers currently run exhaustive,
improve their ability to discover and      lengthy and expensive experiments to
develop new drugs. The former stars of     test antibody-producing cells in order
the show were small molecule drugs but     to identify the MAbs with therapeutical
the drug development market has now        potential that are most suitable for
moved towards larger biological drugs      clinical trials. Technology has not
such as monoclonal antibodies (MAb)        kept pace and this process has been
and it is expected that these drugs will   described as like searching the internet
account for 60% of market growth in the    without Google.
future.

However, there is one key factor that      USP
determines how many new drugs are
developed and the final market price       Innovamab’s multi disciplinary team at
of approved new drugs: the cost of         DCU has developed a technology called
discovering and bringing a new drug        DiCAST which is a new technology
to market. This cost is driven upwards     solution for the early stages of MAb
by the fact that 95% of drugs in           discovery. DiCAST improves the speed
development fail for reasons such as       and quality of screening not only by
toxicity or lack of efficacy in clinical   analysing vastly more cells at one time,
trials.                                    but also by performing several steps in
                                           one iteration (which can take weeks with
                                           other technologies). The combination of
                                           these patented inventions and know how
Looking for the “Golden Egg”               provides a radically improved answer to
                                           the question of ‘how can I find a one in a
Drug development companies have            million MAb with greatest certainty and
established huge banks of monoclonal       greatest probability of success?’
antibodies. As a result, the problem
is not in how to generate vast new         “We are looking for investment to build
amounts of monoclonal antibodies but       a company around the technology and
rather how to test and recognise their     to take it to the world market”, explains
potential and find the one rare MAb        Paul.

Notes

                                                                               2013     21
Gazel
Kevin Doherty

Reinterpretation of
household products

Gazel is a new company creating             Thoughtful, enriching & inviting
products for the home that marry
usability and style with a cutting edge     This product has become the catalyst
design focus. The flagship product, the     for the team to spin out a premium
Effortless Clothes Hanger is a sleek and    homewares company, and is the first
stylish reinterpretation of a household     in a pipeline of products spread across
staple and showcases the design skill of    the different areas of the home, from
the designers Kevin Doherty and Ronan       bedroom to kitchen to living room.
Murphy, both Researchers at the Origin8     The Gazel brand will target the growing
Innovation Hub at NCAD.                     niche of urbanised and sophisticated
                                            consumers throughout Europe, who
                                            seek value-added and innovative
Imaginative lifestyle products              products.
for the home                                The team is seeking investment to bring
The Gazel duo are ‘rethinking the           their exciting products to market.
everyday’ to provide a richer experience
for people, by elevating the ordinary
through inspired design. Kevin and
Ronan take normal household products
and turn them into convenient and
modern objects of real beauty and
distinction.
The novel concept for the Effortless
Clothes Hanger took an everyday object
and reimagined it with universal design
in mind – it allows all manner of clothes
to be hung with minimum effort and
maximum comfort. The hanger even
slips into fully buttoned blouses and
shirts.

Notes

                                                                               2013   23
Web Real Time Communications
                                 Miguel Ponce De Leon

                                 Web real-time
                                 communications

     This web platform for mobiles, laptops     Collaborate and Communicate
     and desktops enables voice, video          online in real time
     and instantanous collaboration using
     your web browser by default to deliver     Developed by the research organisation
     communications in real time.               the TSSG, the business model has been
                                                built around assisting mobile operators
     The collaboration technology allows        in Ireland, Europe and internationally.
     you to connect your web browser            Given that the mobile market has
     peer to peer enabling voice &              reached saturation and the price of
     video conversations, screen sharing        calls is dropping, mobile operators need
     interactions and game playing all at the   additional business productivity tools
     same time.                                 that they can offer companies. This
     This system even allows a person to        product offers business customers a
     use their existing social networking       range of different collaborative options
     environment to take a call from someone    such as having conference calls, and
     on their mobile phone.                     context-based communications, being
                                                able to see each others screens and
     The platform facilitates any two           work on documents in real time using
     computers finding each other via a web     the web.
     browser so that they can connect and
     communicate. There’s no longer a need      “We’ve gained traction in the classified
     to coordinate and synch up Skype id’s      ads market, and require assistance to
     etc as your existing Facebook, Twitter,    accelerate that traction and explore
     mobile number can be used to connect       additional revenue streams.”, explains
     your computers and communicate using       Miguel.
     the peer to peer technology.
     The platform also exposes its p2p
     real time features to web application
     developers via API’s, allowing them to
     integrate the platform into their web
     service.

     Notes

24               2013
CipherDocs
Ed Grant

Cloud data encryption
& control

Many companies today are using the           already been encrypted in real time
Cloud to store, create and share data        when the documents were created or
while others have serious concerns           shared. This means that even though the
driven by both compliance and the            data is held in the Cloud, if a third party
desire to control their data at all times.   wishes to access the data, or it has been
CipherDocs allows corporate users of         shared with someone it shouldn’t have
Cloud platforms, particularly those using    been, all they will see is cipher text.
Office 365 and Google Apps, to encrypt
the documents they are creating,
sharing or storing in real time and allows   The key to encryption
them to retain complete control of who
can access the data.                         CipherDocs has a very simple
                                             proposition: take control of your data in
Without using CipherDocs encryption,         the Cloud in real time. The only way that
Office 365 data is stored, shared            the information that has been encrypted
and created in a clear text form. This       by CipherDocs can be accessed is
precludes companies in some regulated        by sharing a key which you control
industries and certain jurisdictions from    – without the key, the data is never
storing data in the cloud while other        disclosed.
companies simply have concerns over
data control and the threat of a 3rd         “Our objective is to raise up to
party being able to gain access. If the      €500,000 to complete and launch our
corporate user such as a bank, health        Microsoft Office 365 solution.”,
company or insurer, has deployed             explains Ed.
CipherDocs service then that data has

Notes

                                                                                  2013     25
Iconic Translation Machines
                                   Dr. John Tinsley

                                   High quality cloud based
                                   patent translation

     Patent language translation is a long and     The IPTranslator provides the technical
     tedious process. With long sentences          content required in a cost effective
     and technical constructions it is very        manner, it translates to an excellent
     difficult and time consuming exercise,        quality in a very short amount of time,
     this has resulted in 75% of the cost of       leading to a higher level of accuracy and
     filing a patent coming from translation.      productivity and resulting in significant
                                                   savings for customers.
     Patent translation is a specialist skill
     performed by subject matter experts.          This novel cloud-based service can be
     It is crucial that each translation is of a   sector-adapted to target high growth
     very high quality to ensure that it meets     vertical markets within the overall
     all of the legal requirements. Consumers      translation industry.
     want more for less, and sooner, all of
                                                   Resulting from three years R&D, the
     this has led to demand way outstripping
                                                   company already have their first paying
     supply.
                                                   customer on board, the service is also
                                                   being trialled by a number of potential
                                                   clients around the world.
     Facilitating the Translation
     industry and beyond                           “Having launched our flagship offering
                                                   we are now keen to speak with people
     Iconic Translation Machines, a spin-out       who feel they could help accelerate
     company from DCU, have the solution -         our growth and see Iconic Translation
     they have developed advanced Machine          Machines fulfill its potential”, explains
     Translation technology to translate           John.
     one language into another. Their first
     flagship product is IPTranslator which
     is targeting the Patent and Intellectual
     Property (IP) sector.

     Notes

26               2013
Vetex
Dr. Mark Bruzzi

Next generation clot
removal

Vetex is an interventional device for the     chronic, lifestyle-limiting symptoms such
treatment of Deep Vein Thrombosis,            as swelling, pain, and ulceration of the
which is the formation of a blood             affected limb.
clot inside the leg. This can happen
                                              Other therapies focus on mechanically
for a variety of reasons associated
                                              disrupting and/or dissolving the clot
with surgery or anything that causes
                                              with limited success and often requiring
a restriction in blood flow within the
                                              long term treatment in an intensive care
venous system.
                                              setting, resulting in significant cost to
In the US alone, it is estimated that         the healthcare system.
DVT causes 600,000 people to be
hospitalized each year, with the resulting
Pulmonary Embolism (PE) leading to            Efficient and effective
more than 100,000 deaths. DVT and PE          clot removal
are responsible for 1 in 10 hospital deaths
annually (US figures). Some estimates         The Vetex device can catch large
suggest that these conditions cause           volumes of the clot in a matter
more deaths each year than breast             of minutes reducing the need for
cancer, AIDS, or motor vehicle incidents.     thrombolitics and the need for long
                                              term stay in the intensive care unit.
Vetex was developed in conjunction            The device has three component parts
with Gerry O’Sullivan, an interventional      including a macerating and extraction
radiologist in Galway and leading expert      mechanism attached to a basket, this is
in the treatment of the disease. He           inserted into the venous system behind
identified a problem and worked with          the knee and pushed to the location of
Mark Bruzzi, a biomedical engineer            the clot. The device’s efficient capturing
and his research team to create a novel       mechanism can then extract large
device to treat the condition.                volumes of clot across a wide range of
Current standard therapy for the disease      vessel diameters.
involves the use of anti-coagulation          “Our objective is to secure investment
(blood thinning) drugs but while this         and a commercial team to bring this
limits the development of the clot, it        technology to the European and US
does not dissolve it which can result in      market.”, explains Dr. Bruzzi.

Notes

                                                                                   2013    27
Style-Eyes
Dr. Mark Hughes

The future of fashion
retail

The concept is quite straight forward:       Searching for a needle
Style Eyes is a search engine that will      in a haystack
find that dress, pair of shoes or handbag
that you have spotted out and about          As creator Mark Hughes explains; if you
and want to buy.                             ever looked for a specific garment in
                                             a search engine, you’ll know you get
Simply take a picture with your Smart        thousands of results with hundreds of
Phone and using their image recognition      these coming from online catalogues,
technology – and a network of retail         making online searching labourious and
partners - Style Eyes allows you to source   in many cases fruitless.
the item and buy it!                         While image recognition is becoming
After nine months of development, Style      very popular and will over time become
Eyes launched onto the Irish market at       ubiquitious, clothes have always proved
Dublin Fashion Festival 2013.                difficult to capture because they
                                             deform with peoples bodies, so visually
Over 300 of the leading fashion retailer’s   that’s a real challenge. Style Eyes have
dresses, skirts, tops, bags, shoes and       developed the technology to get around
accessories are on the Style Eyes system     this.
(all with commercial agreements in
place) so that all you have to do is         Designed for ‘anyone interested
simply take a picture, and the app will      in fashion’, the multi platform app
source it for you.                           is free to users as revenues come
                                             from agreements with retailers via
                                             traffic delivered to retailer sites and a
                                             percentage of any purchase.
                                             Mark is looking to meet people who can
                                             “help Style-Eyes reach its full potential”.

Notes

                                                                                   2013    29
30   2013
MR Gum Innovation
Eamon Murphy

Biodegradable, non-stick
chewing gum

Chewing gum has become an enormous         Eamon is an experienced food executive
littering problem and negatively affects   and an Enterprise Ireland Business
the environment. Because of its non-       Partner and has spent considerable
biodegradable nature, gum does not         time seeking out commercial innovation
dissolve or decompose and each             opportunities at Irish third level
piece left untreated lingers around for    institutions.
decades. Eamon Murphy and Dr Liam
                                           The promoters will work with the
Ryan have teamed up to develop and
                                           experienced team at Agri-food and
launch their solution to this world wide
                                           Biosciences Institute (AFBI) in Belfast
problem, a biodegradable, non-stick
                                           to further develop and scale-up the
chewing gum.
                                           technologies.
The duo have already developed
prototypes and aim to launch a chewing
gum with improved functionality over       The Mission
products currently on the market. The
solution uses technology originally        The mission of MR Gum Innovation
developed by Professor Elke Arendt and     is to develop and launch an exciting,
Dr Ryan in UCC, supplemented by other      innovative and environmentally-friendly
related technologies to provide a food-    chewing gum brand. The technology
based alternative to the current rubber/   also has multiple applications across
latex based gum products.                  both food and pharmaceutical fields.

The gum will be produced using a           MR Gum Innovation is currently at
multi-stage development platform,          prototype stage and is investment ready.
combining a number of novel processing     “Our objective is to secure investment
techniques. This will allow for the        and support to help us turn what should
targeted and time-controlled release of    be into what is.”, says Eamon.
functional molecules to create a variety
of customised products including longer
lasting and multi-flavoured gums.

Notes

                                                                               2013   31
Vasgard
                                 Pat Hobbert

                                 Varicose vein
                                 prevention

     Globally, one in four people will suffer    A first of its kind
     from varicose veins with 30% of females
     and 25% of males presenting symptoms        The device is a sensor which, after
     at some stage in their lives. Besides       initial measurements and fitting,
     being a cosmetic problem, varicose          is worn by the patient beside the
     veins can be painful, especially while      knee joint for 48 hours.
     standing. Up until recently, little could   The sensor continously monitors the
     be done to treat the early stages of the    venous blood pressure of the patient
     condition.                                  and identifies the patient’s specific
     The only option available to people         behaviours that lead to harmful venous
     was surgical intervention (such as          pressures. The technology involves
     vein stripping procedures) in order to      complex, patent-pending, algorithims
     treat the more advanced stages of the       which calculate the leg’s venous blood
     disease. The main controllable factor       pressure, providing personalised,
     in the development of varicose veins is     highly specific feedback and lifestyle
     “venous hypertension” or high blood         advice. The product will be supplied
     pressure in the veins which causes          to clinicians to enable them to provide
     the veins to stretch and distort. By        a new varicose vein screening service
     reducing this venous blood pressure         for people with, or concerned about
     throughout the course of the day, one       developing varicose veins.
     can prevent varicose veins from forming     Connected via desktop computer
     or worsening. An NUIG research team         software, the sensor technology will
     have developed the VASGARD sensor, a        automatically generate an in-depth,
     technology-based product which non-         high value, consultation report which is
     invasively measures venous pressure in      easy to understand which the patient
     the veins of the lower leg. The device      can take away with them. The avoidance
     also offers an opportunity to proactively   of deteriorating veins by following that
     screen a patient to determine what life-    advice will be significantly beneficial to
     style factors are predisposing them to      the potential patient.
     varicose veins and to take the necessary
                                                 “Our objective is to secure funding,
     avoidance action.
                                                 ideally from Investors, who can provide
                                                 expertise in addition to finances“, says
                                                 Pat.
     Notes

32               2013
WRIPL
Dr. Kevin Koidl

Driving traffic to
online businesses

The number of online businesses is             Interest profile
exploding, with global e-commerce
sales topping $1 trillion for the first time   WRIPL’s aim is to build a long term
in 2012. But, how do you make your             interest profiles in consumers. One of
business stand out in this busy space?         the USPs is the fact that it doesn’t use
And how do you drive more traffic to           Cookies so developing an interest profile
your site?                                     over the long term on behalf of its online
                                               partner’s allows WRIPL to correlate with
WRIPL has the answer, WRIPL                    that partner’s content and push relevant
technology will suggest relevant stories/      articles based on interest.
products from your site to consumers
who have expressed an interest in the          A unique feature of WRIPL is that the
area.                                          service can be applied to different
                                               websites and services the consumer
Consumers sign up to WRIPL and                 is using. This allows WRIPL to unify
create an interest profile, WRIPL then         the users experience and recommend
constantly updates the profile from            relevant content based on the users
across the web by gathering information        broad interests. As it is service based
about their activities – what they are         WRIPL can continue the browsing
reading, what they are clicking on etc.        experience across devices such as
This interest profile can recommend            Mobile, Tablet and Desktop.
articles and products that are relevant
and interesting to the user over time.         WRIPL’s technology can increase the
                                               user experience by having a greater
If a reader is clicking on content about       relevance of content and also the
Brian O’Driscoll for instance, WRIPL will      revenue of the online partner by driving
suggest rugby related content to the           traffic to their website.
consumer.                                      “Our objective is to reach out to
                                               additional customers and secure
                                               investment”, says Kevin.

Notes

                                                                                   2013     33
Ata-Bot
                                 Dr. Deirdre Hogan

                                 Targeted online
                                 advertising

     Nowadays, more and more companies           Processing noisy language
     are concentrating their efforts on online   naturally
     advertising, print ads are slowly but
     surely becoming a thing of the past.        The technology is born out of DCU
                                                 which has an expertise in technology for
     Ata-Bot is a technology which looks at      accurately processing human language.
     user generated content such as Twitter      User-generated content contains lots
     posts, publicly available Facebook          of typos, errors, slang and emoticons
     comments and content generated on           and this degrades the accuracy of most
     forums. Ata-Bot can understand the          text analytic tools, which are trained
     intent expressed by the customer in the     on well edited text such as newspaper
     threads of these conversations, which it    articles. Ata-bot technology is trained
     links back to the service provider. The     to accurately understand “noisy” user-
     service provider in turn delivers more      generated content.
     relevant ads to the customer in real time
     by offering products or services that       The digital advertising industry
     directly address the needs the person is    generated a record-breaking $9.6
     expressing online.                          billion in revenue for Q1 2013. Currently
                                                 advertisers can target consumers
     Ata-Bot was trialled by analysing           through a variety of ways, including
     Twitter data in relation to the telecoms    through demographic information and
     domain, seeking out users who have          browsing history, Ata-Bot has created a
     expressed an intent to switch provider.     niche approach to targeting consumers
     This information would be very useful to    by utilising their own user generated
     rival service providers who can target      content.
     consumers who are possibly looking
     to ‘churn’. In the same way, people         “Ata-Bot is attending the Big Ideas
     talking about when is the latest version    Showcase with a view to meeting
     of a phone coming out are possibly          potential Technology Partners to trial
     expressing an intent to buy a new           our software” says Hogan.
     product.

     Notes

34               2013
Notes

        2013   35
Notes

36           2013
Notes

        2013   37
Notes

38           2013
Notes

        2013   39
Notes

40           2013
WE’RE OPEN TO NEW IDEAS
ESPECIALLY YOURS

 It all starts with a cup of coffee...
 ●   Whatever your research work’s nature or stage

 ●   Whatever the stage of your career

 ●   Whether you are working alone or in a team

 ●   Whether you have proof of concept or not

 The Commercialisation Fund programme enables researchers
 to develop innovations through Commercial Case Feasibility
 and Commercialisation Fund Project grants.

 Get in touch to find out how we can help you take your
 research to the next stage.

 www.enterprise-ireland.com/commercialisation
THANKS FOR ATTENDING

                      SHOWCASE 2013
                              25th September, Aviva Stadium

CONTACT

big.ideas@enterprise-ireland.com

Research and Innovation Business Unit
Enterprise Ireland
The Plaza
East Point Business Park
Dublin 3

www.enterprise-ireland.com/bigideas
                                                              © Enterprise Ireland Sept 13 - (338)
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