BioMAT 2015 Program Euro 21 - 22 April 2015 - Weimar, Germany European Symposium and Exhibition on Biomaterials and Related Areas - Deutsche ...
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Program
Euro
BioMAT
2015
European Symposium and
Exhibition on Biomaterials
and Related Areas
21 - 22 April 2015
Weimar, Germany
www.dgm.de/biomat
BioMAT2015 - Overview
Time Tuesday, 21.4.2015 Time Wednesday, 22.4.2015
8:00 Poster Mounting/Registration Room Goethe BioMAT
Room Goethe 8:00 Plenary
European Symposium on Biomaterials
9:00 Welcome Address: Prof. W. Rosenthal 8:30 Plenary
and Related Areas
President of FSU Jena 9:00 Coffee Break
9:15 Plenary Room Goethe Room Bach Room Schiller
9:45 Plenary Topic N Topic B Topic S
21. - 22. April 2015
10:15 Coffee Break 9:40
Weimar, Germany
Room Goethe Room Bach Room Schiller 10:00
Topic A Topic Q Topic H 10:20
11:00 10:40
11:20 11:00 Coffee Break
11:40 Topic D Topic B Topic S
12:00 11:30
12:20 11:50
12:40 Lunch Break 12:10
Topic I Topic C Topic F 12:30
14:00 12:50
14:20 13:10 Lunch Break
14:40 Topic D Topic M Topic G
15:00 14:15 Program Overview 2
Scope 4
15:20 14:35
Program Committee 5
15:40 Coffee Break 14:55 Topic L Plenary Lectures Tuesday 7
Topic I Topic C Topic F 15:15 Short Break Lectures Program Tuesday 9
16:10 Topic D Topic P RoundTable Plenary Lectures Wednesday 14
16:30 15:20 RoundTable
Lectures Program Wednesday 16
Round-Table Discussion 20
16:50 15:40 RoundTable
Poster Program 23
Room Goethe 16:00 RoundTable List of Authors 35
17:10 40 Oral Poster Presentations 16:20 List of Participants 40
(3 minutes short-lectures) 16:25 Announcement of the Posteraward General Information 45
19:30 Posterdiscussion with and Closing Address
Conference Fees 46
Sightseeing-Tour 47
Snacks and Drinks
Otto Schott Institute of Materials
and networking in the foyer 16:40 End of the Conference Research ((OSIM) 49
List of Exhibitors 50
Map of Weimar 54Scope Program Committee
The international symposium Euro Euro BioMat 2015 with more than
BioMat 2015 addresses the gro- 200 participants from 25 countries
wing interest of science, industry all over the world brings together
and medicine in the different fascinating science and stimulating
aspects of the creation, characte- people in a delightful setting in
rization, testing and application of Weimar in the very heart of Euro-
biomaterials and closely related pe.
materials. The program committee of Euro
BioMat 2015 is pleased to announ-
The motivation is not only the ce the following plenary talks: Klaus D. Jandt Thomas F. Keller
Klaus D. Jandt recent scientific progress and new Institute of Materi- Deutsches Elek-
Otto Schott Institute of Materials challenges of this exciting, strongly From Biological Self-Assembly to als Science & Tech- tronen-Synchrotron
Research (OSIM), Jena interdisciplinary field of science Peptide Nanostructures of Unique nology (IMT), Jena - DESY, Hamburg
Chairman and engineering but also that Chemical and Physical Properties Chairman Vice-Chairman
engineers, materials scientists, Prof. Dr. Ehud Gazit, Tel Aviv
physicists, chemists, biologists in University, Israel
industrial R&D as well as medical
professionals are increasingly Cell-instructiveSurfaces via Nano-
facing situations where materials topography
are challenged by high performan- Prof. Dr. Bo Su, University of
ce requirements and a complex Bristol, UK
biological environment at the same
time. Nano-Structurd Biomaterials for
Regenerative Tissue Engineering
The DGM and its panel of experts Peter Lelkes, Temple University Liga Berzina- Aldo R. Boccaccini Gabriela Ciapetti Matthias Epple John Hunt
in biomaterials address these deve- Philadelphia, USA Cimdina University of Rizzoli Orthopaedic University of University of
lopments with the European sym- Riga Technical Erlangen-Nür nberg Institute, Bologna Duisburg-Essen Liverpool (UK)
Thomas F. Keller posium Euro BioMat 2015 in beau- Reduction of implant-associated University (LV) (IT)
Deutsches Elek- tiful Weimar with its rich cultural infections - a clinical view
tronen-Synchrotron heritage and classical sites. Prof. Dr. Volker Alt, Justus-Lie-
- DESY, Hamburg At Euro BioMat 2015, the current big-University Giessen (Ger-
Vice-Chairman state of progress in biomaterials many)
science and in industry will be pre-
sented and discussed. Moreover, We look forward to welcoming
this symposium stimulates the you in Weimar on the 21th -22th
scientific exchange on several of April 2015.
topics with major challenges and Klaus D. Jandt, Otto Schott
urgent need for novel engineering Institute of Materials Research
approaches as, e.g., in the fields of (OSIM), k.jandt@uni-jena.de
antimicrobial biomaterials, bioac-
tive and biodegradable materials, Thomas F. Keller, Deutsches Willi Jahnen- Petra Kluger João F. Mano Giovanni Marletta Werner E.G.Müller
and drug and gene delivery, to Elektronen-Synchrotron DESY, Dechent Fraunhofer Institute University of University of University Medical
name only a few. thomas.Keller@desy.de RWTH Aachen Uni- for Interfacial Minho, Braga (PT) Catania (IT) Center of the
versity, Germany Engineering and Johannes Gutenberg
Biotechnology, University, Mainz
4 Stuttgart 5Program Committee (continued) Tuesday, 21. April 2015
Plenary Lectures
8:00 Poster Mounting and Registration
Room Goethe
9:00 Welcome Address
Prof. Dr. Walter Rosenthal, President of Friedrich-Schiller University Jena
Plenary Lectures
Chair: K.D. Jandt, Chairman of the conference, Friedrich-Schiller-University Jena
9:15 From biological self-assembly to peptide nanostructures of
Erhan Piskin Kurosch Rezwan Thomas Scheibel Reinhard Norman Stark
- unique chemical and physical properties
Hacettepe University of University of Schnettler Biotronik AG,
9:45
University, Ankara Bremen Bayreuth University Hospital Bülach, CH
E. Gazit, Tel Aviv University (Israel)
(TR) Gießen and Marburg
GmbH, Gießen
Organic nanotechnology is clearly a new front in the field of molecular self-assembly of new structures and composi-
te families at the nano-scale. Our works on the mechanism of aromatic peptide self-assembly, lead to the discovery
that the diphenylalanine recognition motif self-assembles into peptide nanotubes with a remarkable persistence
length. Other aromatic homodipeptides (including those with non-coded amino acids as DOPA) could self-assemble
in nano-spheres, nano-plates, nano-fibrils and hydrogels with nano-scale order. The modification of peptide building
blocks with the Fmoc protecting group allows the formation of hydrogels with nano-scale order. We demonstrated
that the peptide nanostructures have unique chemical, physical and mechanical properties including ultra-rigidity as
aramides, semi-conductive, piezoelectric and non-linear optic properties. We also demonstrated the ability to use
David Watts Frank Witte
these peptide nanostructures as casting mould for the fabrication of metallic nano-wires and coaxial nano-cables.
University of Charité-Univer-
The application of the nanostructures was demonstrated in various fields including electrochemical biosensors, tissue
Manchester (UK) sitätsmedizin, Berlin
engineering, and molecular imaging. We had developed ways for depositing of the peptide nanostructures and their
organization. We had use inkjet technology as well as vapour deposition methods to coat surface and from the pept-
ide “nano-forests”. We recently demonstrated that even a single phenylalanine amino-acid can form well-ordered
fibrilar assemblies of distinct electron diffraction pattern and toxic properties. The combination of DNA properties
and peptide backbone in the form of Peptide Nucleic Acid (PNA) resulted in light emitting assemblies that exhibit
both stacking and Watson-Crick base-pairing.
6 7Tuesday, 21. April 2015 Tuesday, 21. April 2015
Plenary Lectures Lectures
Room Goethe Goethe Bach Schiller
Plenary Lectures A: Antimic. biomat. & biofilms Q: Hydrogels & biob. polymers H: Biological materials
Chair: K.D. Jandt, Chairman of the conference, Friedrich-Schiller-University Jena Chair: E. Gazit, Tel Aviv University Chair: B. Su, University of Bristol Chair: T. Scheibel, University of
(Israel) (UK) Bayreuth (Germany)
9:45 Cell-instructive Surfaces via Nanotopography
- 11:00 Bacteria on surfaces – Polyelectrolyte complex par- Fire as a trigger for plant
10:15 B. Su, University of Bristol (UK) engineering bio-inspired ticles: A versatile tol for seed release
microstructures to control drug delivery and biomedi- V. Schoeppler (Sp), J. Huss, Max
bacterial adhesion and bio- cal applications Planck Institute of Colloids and
film growth M. Müller (Sp), B. Torger, D. Vehlow, Interfaces, Golm (Germany); D. Mer-
D. Asker, N. Lavielle, B. Hatton (Sp), B. Urban, Leibniz Institute of Poly- ritt, Botanic Gardens and Parks Aut-
University of Toronto (Canada) mer Research Dresden (Germany); B. hority, Perth (Australia); P. Fratzl, M.
Woltmann, D. Wehrum, Technische Eder, Max Planck Institute of Col-
Smart materials which can deter bacteria while enhance tissue integration are Universität Dresden (Germany); C. loids and Interfaces, Golm (Ger-
highly desirable for application in implants where there is often a competition between host tissue cell integration Striegler, D. Appelhans, Leibniz Insti- many)
and bacterial colonisation at their surfaces. It has been known that both eukaryotic and prokaryotic cells are respon- tute of Polymer Research Dresden
sive to chemical and physical cues of material surfaces under complex physiological conditions. The question is (Germany)
whether we can utilise their different responses to rationally design medical implants or devices that possess cell-
instructive characteristics. Here we show that a straightforward physical rationale - nanotopography, can be
engineered into titanium substrates to elicit differential cell responses. The inspiration comes from cicada wings 11:20 PLGA Nanoparticles against Polyhydroxyalkanoates pro- Rheological characterisation
whose surfaces have been shown to display bactericidal nanopillar patterns. The engineered surfaces in this work are Staphylococcus aureus: duction with Ralstonia of human blood in the oscil-
titania (TiO2) nanowire arrays that (i) are selectively bactericidal against motile bacteria, and (ii) can guide mammali- Effect of Size, Adsorbed PEG eutropha from low quality lating shear field
an cell proliferation and differentiation according to their hierarchical structure of nanowire arrays. These cell-instruc- and Loaded Ciprofloxacin animal waste fats U. Windberger (Sp), C. Poeschl,
tive properties, together with the ease of fabrication of these titania nanowires, hold great promise for fabrication of C. Gheffar (Sp), C. Karakasyan-Dia, T. S.L. Riedel (Sp), Fraunhofer Institut Medical University Vienna (Austria)
smart implants used in orthopaedics and dentistry. Jouenne, D. Le Cerf, Université de für Produktionsanlagen und Kon-
Rouen, Mont Saint Aignan Cedex struktionstechnik, Berlin (Germany);
(France) S. Jahns, Technische Universität Ber-
lin (Germany); E. Uhlmann, Fraunho-
fer Institut für Produktionsanlagen
und Konstruktionstechnik, Berlin
10:45 (Germany); U. Stahl, Technische Uni-
- Coffee Break versität Berlin (Germany) 11:20:00
11:00
11:40 Antimicrobial materials for Injectable self-gelling com- Ultrastructural and mecha-
food packaging application posite scaffolds based on nical characterization of
C. Hauser (Sp), J. Thielmann, T. gellan gum hydrogel and dental enamel
Sentürk-Parreidt, Fraunhofer IVV, ion-loaded zeolites T.E.L. E.D. Yilmaz (Sp), G.A. Schneider,
Freising (Germany) Douglas (Sp), Ghent University (Bel- Hamburg University of Technology
gium); A.L. Skwarczynska, J. War- (Germany)
chol, Rzeszow University of Techno-
logy (Poland); B. Lucas, K. Braeck-
mans, A.G. Skirtach, Ghent Universi-
ty (Belgium)
8 9Tuesday, 21. April 2015 Tuesday, 21. April 2015
Lectures Lectures
Goethe Bach Schiller Goethe Bach Schiller
A: Antimic. biomat. & biofilms Q: Hydrogels & biob. polymers H: Biological materials I: Biomaterials applications C: Bioactive materials F: Bioinspired Materials
Chair: E. Gazit, Tel Aviv University Chair: B. Su, University of Bristol Chair: T. Scheibel, University of Chair: E. Piskin, Hacettepe Chair: K. Salma-Ancane, Riga Chair: K. Rezwan, University of
(Israel) (UK) Bayreuth (Germany) University, Ankara (Turkey) Technical University, (Latvia) Bremen (Germany)
12:00 Evaluating results of ISO Controlling the Properties Nanocrystalline hydroxya- 14:00 Coatings Made of Recom- Microstructured bioactive Synthesis and evaluation of
22196 antimicrobial activity of Fluorescent Nanodia- patite coatings by conversi- binant Spider Silk Proteins glass for triggered cell res- plantlike inorganic structu-
tests monds: the View from Che- on of calcium carbonate for Biomedical Applications ponse in bone replacement res for fluid transport
J. Kuever (Sp), Bremen Institute for mistry and Physics Sides nanostructures C. Borkner (Sp), S. Wohlrab, G. Lang, applications K. Nickel (Sp), M. Keuper, A. Roth-
Materials Testing (Germany); J. Bos- P. Cigler, Academy of Sciences of the J. Holopainen (Sp), K. Kauppinen, K. D. Andreeva-Bäumler, University of M. Hoener (Sp), B. Pföss, R. Conradt, Nebelsick, Eberhard-Karls-University
sert, Friedrich Schiller University Jena Czech Republic, Prague (Czech Mizohata, E. Santala, J. Tuukkanen, Bayreuth (Germany); K. Skorb, Max RWTH Aachen University (Germany); of Tübingen (Germany)
(Germany) Republic) M. Ritala, University of Helsinki (Fin- Planck Institute of Colloids and H. Fischer, RWTH Aachen University
land) Interfaces, Potsdam (Germany); H. Hospital (Germany)
Bargel, T. Scheibel, University of Bay-
reuth (Germany)
12:20 Metallic copper as an anti- Biologically inspired adhesi- Covalent Coating of Human
microbial agent for infec- ve polymer suction cups by Extracellular Matrix on Tita-
tion prevention two-photon and imprint nium Implant Surfaces using
M. Hans (Sp), F. Mücklich, Saarland lithography Click Chemistry 14:20 Ultrathin Yttria-Stabilized Selenium Doped Hydroxya- Switchable Bio-inspired
University, Saarbrücken (Germany) S.C.L. Fischer (Sp), Saarland Univer- M. Ruff (Sp), University of Stuttgart Zirconia Sheets for Biomedi- patite Coating on Titanium Adhesives
sity, Saarbrücken (Germany); R. Hen- (Germany); D. Wieland, University of cal Applications Alloy E. Kroner, Leibniz-Institute for New
sel, E. Arzt, INM-Leibniz Institute for Konstanz (Germany); M. Bach, G. C. Le Coadou (Sp), N. Karst, F. B. Yilmaz, Z. Evis (Sp), A. Tezcaner, S. Materials GmbH, Saarbrücken (Ger-
New Materials, Saarbrücken Tovar, University of Stuttgart (Ger- Emieux, H. Fournier, G. Lorin, O. Banerjee, Middle East Technical Uni- many)
many); V. Wittmann, University of Sicardy, A. Montani, G. Bernard- versity, Ankara (Turkey)
Konstanz (Germany); P. Kluger, Granger, J.-P. Simonato, CEA, Greno-
Fraunhofer Institute for Interfacial ble (France); J. Chevalier, INSA Lyon
Engineering and Biotechnology, (France)
Stuttgart (Germany)
14:40 Theranostic Aimed Nanoab- Modified poly(vinyl alco- Wood derived bio-scaffolds
sorbers in Antenna Modulus hol)-hydroxyapatite micros- for multifunctional materi-
Radiofrequency Hyperther- pheres for bone tissue als tailored through chemi-
mia (A Comprehensive engineering cal delignification
12:40 Study) K. Salma-Ancane (Sp), L. Stipniece, J. Segmehl (Sp), T. Keplinger,
- Lunch Break B. Nasseri, M. Yilmaz, Hacettepe V. Rjabovs, J. Locs, L. Berzina-Cimdi- I. Burgert, ETH, Zurich (Switzerland)
14:00 University, Ankara (Turkey); M. Turk, na, Riga Technical University (Latvia)
Kirikkale University (Turkey); I.C.
Kocum, Baskent University, Ankara
(Turkey); E. Piskin (Sp), Hacettepe
University, Ankara (Turkey)
10 11Tuesday, 21. April 2015 Tuesday, 21. April 2015
Lectures Lectures
Goethe Bach Schiller Goethe Bach Schiller
I: Biomaterials applications C: Bioactive materials F: Bioinspired materials I: Biomaterials applications C: Bioactive materials F: Bioinspired materials
Chair: E. Piskin, Hacettepe Chair: K. Salma-Ancane, Riga Chair: K. Rezwan, University of Chair: F. Veronesi, Rizzoli Orthopedic Chair: G. Marletta, University of Chair: B. Garipcan, Bogazici Univer-
University, Ankara (Turkey) Technical University, (Latvia) Bremen (Germany) Institute, Bologna (Italy) Catania (Italy) sity, Istanbul (Turkey)
15:00 Biobased polymers in multi- Mechanical Assessment and Coacervate-directed CaCO3 16:10 Comparison of the Antire- Poly(ethylene oxide)-b-poly A new concept of composite
component injection moul- In-vitro Biocompatibility of microcarriers for pH-respon- sorptive Properties of Stron- block copolymers for calci- inspired to the bone osteo-
ding Pure and Sr Doped Zirconi- sive delivery of biomolecu- tium and Alendronate on an um phosphate mineralizati- nal structure
R. Rinberg, L. Kroll, Chemnitz Uni- um-calcium-silicate les ovariectomized Rat Spinal on and biofilm inhibition F. Libonati (Sp), L. Vergani, Politecni-
versity of Technology (Germany); C. (Ca3ZrSi2O9) Bioceramics V. Lauth (Sp), M. Maas, R. Rezwan, Arthrodesis Model T. Mai (Sp), K. Bleek, C. Günter, A. co di Milano (Italy)
Staudigel (Sp), SKZ Würzburg (Ger- T. Schumacher (Sp), A. Aminian, E. University of Bremen (Germany) F. Salamanna (Sp), A. Parilli, G. Gia- Taubert, University of Potsdam,
many); F. Tautenhain (Sp), Chemnitz Volkmann, H. Lührs, A. Wolf, D. Pede, varesi, E. Boanini, A. Bigi, M. Fini, Golm (Germany); E. Rakhmatullina,
University of Technology (Germany) L. Treccani, K. Rezwan, University of Rizzoli Orthopaedic Institute, Bolo- Z. Cheaib, S. Eick, A. Lussi, Univ. of
Bremen (Germany) gna (Italy) Bern (CH); S. Boye, A. Lederer, Leib-
niz Inst. of Poly. Research Dresden; J.
Yuan, A. Völkel, M. Gräwert. MPI of
Colloids and Interfaces, Potsdam
15:20 The innovative polyuretha- Increased new-bone forma- Interface-controlled calcium 16:30 Crystalline calcium alendro- Tuning the Nanoparticles Cartilage Mimicked Surfaces
ne utilization in novel Polish tion induced by a macro- phosphate mineralization: nate obtained by octacalci- Surface: Effect of Polyethy- M.Ö. Özturk, Bogaziçi University, Ist-
extracorporeal pulsatile porous, strontium-enriched effect of oligo(aspartic um phosphate digestion: lene Glycol on the In-situ anbul (Turkey); D. Hür, Anadolu Uni-
heart support devices Reli- xerogel-scaffold in a meta- acid)-rich interfaces structure and in vitro beha- Adsorption of Proteins versity, Eskisehir (Turkey); L. Uzun, B.
gaHeart physeal fracture defect in D. Hentrich (Sp), M. Junginger, A. vior B. Pelaz (Sp), Philipps Universität Çelebi, E. Keç, D.U. Çetinkaya,
R. Kustosz (Sp), Foundation for Car- ovariectomized rats. Taubert, University of Potsdam (Ger- F. Veronesi (Sp), P. Torricelli, M. Fini, Marburg (Germany); P. del Pino, CIC Hacettepe University, Ankara (Tur-
diac Surgery Development, Krakow U. Thormann (Sp), Justus-Liebig Uni- many); M. Bruns, Karlsruhe Institute Rizzoli Orthopedic Institute, Bologna biomagune, San Sebastian (Spain); key); B. Garipcan (Sp), Bogaziçi Uni-
(Poland); M. Gonsior, A. Kapis, Foun- versity, Giessen (Germany); T. Hanke, of Technology (Germany); H.G. Bör- (Italy); E. Boanini, A. Bigi, University M. Gamal, R. Hartman, W.J. Parak, versity, Istanbul (Turkey)
dation for Cardiac Surgery Develop- Technische Universität Dresden (); T. ner, Humboldt Universität zu Berlin of Bologna, M. Gazzano, ISOF-CNR, Philipps Universität Marburg (Ger-
ment, Zabrze (Poland); P. Jurkowski, El Khassawna, U. Sommer, M. Rohn- (Germany); J. Brandt, G. Brezesinki, Bologna (Italy) many)
Z. Narojek, WADIM PLAST Narojek, ke, Justus-Liebig University, Giessen Max Planck Institute of Colloids and
Michaowice (Poland) (Germany); V. Alt, Justus-Liebig Uni- Interfaces, Potsdam (Germany)
versity, Gießen (Germany) 16:50 Baltic Sea Network for Bio- Improved Biocompatibility Reduced platelet adhesion
material Composites of Polyetheretherketone on microstructured PDMS
J. Bossert, Friedrich Schiller Universi- (PEEK) by Coating with Thin surfaces under shear condi-
ty of Jena (Germany) Titania Films tions
15:40 N. Wendt (Sp), H. Fullriede, G. Zahn, T.T. Pham, C. Lüdecke-Beyer (Sp),
- Coffee Break P. Behrens, Leibniz Universität Han- K.D. Jandt, J. Bossert, S. Maenz, Frie-
16:10 nover (Germany); B. Rais, P.P. Müller, drich Schiller University Jena; S. Wie-
Helmholtz Centre for Infection Rese- demeier, G. Gastrock, Institute for
arch, Braunschweig Bioprocessing and Analytical Measu-
rement Techniques, Heilbad Heiligen-
stadt, U. Settmacher, J. Zanow, Jena
University Hospital
17:10 Oral Poster Presentations; SessionChair: C. Lüdecke-Beyer, Friedrich-Schiller-University Jena
(3 minute Short Lecture of each Oral Poster)
19:30 Posterdiscussion with Snacks and Drinks in the Foyer of the lecture halls
Posterevening Barbeque
12 13Wednesday, 22. April 2015 Wednesday, 22. April 2015
Plenary Lectures Plenary Lectures
Room Goethe Room Goethe
Plenary Lectures Plenary Lectures
Chair: T.F. Keller, Deutsches Elektronen-Synchrotron - DESY, Hamburg (Germany) Chair: T.F. Keller, Deutsches Elektronen-Synchrotron - DESY, Hamburg (Germany)
8:00 Nano-Structurd Biomaterials for Regenerative Tissue Engineering 8:30 Reduction of implant-associated infections – a clinical view
- -
8:30 P. Lelkes, Temple University, Philadelphia , PA (USA) 9:00 V. Alt, Justus-Liebig-University Giessen (Germany)
Peter I. Lelkes is the Laura H. Carnell Professor and Founding Chair of the Department of Bioengineering in the Col- Implant-associated infections remain a huge challenge in orthopaedic and orthopaedic trauma surgery and there is a
lege of Engineering at Temple University. Dr. Lelkes is also the Inaugural Director of the Institute for Regenerative tremendous need for antimicrobial biomaterials. The intention of this work is to highlight the clinical perspective,
Medicine and Engineering (TIME) at Temple University's School of Medicine and Professor for Cancer Biology at the underlying pathophysiological mechanisms and surgical treatment options for implant-asssociated infections with a
Fox Chase Cancer Center. Prior to that he was from 2000-2011 the Calhoun Chair Professor in the School of Biome- focus on antimicrobial biomaterials. Biofilm-building and intracellular invasion strategies are among the most rele-
dical Engineering, Science and Health Systems at Drexel University in Philadelphia with adjunct appointments in the vant virulence factors of bacteria involved in implant infections. Biomaterials are of high interest as they enable the
Departments of Mechanical Engineering and Mechanics (College of Engineering) and Pathology, Biochemistry and local delivery of antibiotics to the wound without any significant systemic side effects. Ideal biomaterials for the use
Surgery (College of Medicine). Currently Prof. Lelkes directs a broad interdisciplinary program in regenerative tissue in implant-associated bone infections should be safe in its use without disturbance of wound healing and biodegra-
engineering, focusing on nanotechnology-based biomaterials and soft tissue engineering, employing developmental dable without the need for removal of the material. Furthermore, it should enable the loading with different antibio-
biological principles to enhance the tissue-specific differentiation of embryonic and adult stem cells towards pulmo- tics according to the antibiogram of the infection causing germ and ensure reliable release kinetics above the mini-
nary, cardiac and neuronal lineages. Dr. Lelkes has organized several Keystone conferences, published more than 190 mal inhibitory concentration of the bacteria. Osteoconductive or even osteoinductive properties are desirable for the
peer-reviewed papers, authored several books and more than 50 book chapters and made more than 400 presenta- enhancement of new bone formation. Close cooperation between material researches, clinicians and the industry is
tions nationally and internationally. needed is needed for the improvement of antimicrobial biomaterials in the future.
Dr. Lelkes' basic and translational research has been support by federal (NIH, NSF, NASA, DOE) and state funding
agencies (NTI and PA Dept. of Commerce, Tobacco Settlement Funds) and private Foundations, including the Craig H.
Neilsen Foundation and the Coulter Foundation. Dr. Lelkes has been the team leader for tissue engineering at the
Nanotechnology Institute of Southeastern Pennsylvania (NTI) and is the Co-Director of PATRIC, the Pennsylvania
Advanced Textile Research and Innovation Center, focusing on BioNanoTextiles and Stem Cell Biology.
Dr. Lelkes has received numerous honors and awards, nationally and internationally. Amongst them a Forchheimer
Visiting Fellowship at the Hebrew University, Jerusalem, Honorary Professorships at the University of Applied Sciences
Aachen, Germany and the Changchun Institute of Polymer Chemistry and Physics, Chinese Academy of Sciences, and
a Distinguished Visiting Fellowship of the Royal Academy of Engineering at Imperial College, London, UK. In 2011 he
was inducted as a Fellow of the AIMBE (American Institute for Medical and Biological Engineering) and received the
2012 Ben Franklin Key Award from IEEE, the Institute of Electrical and Electronics Enginee
9:00 - 9:40 Coffee Break
14 15Wednesday, 22. April 2015 Wednesday, 22. April 2015
Lectures Lectures
Room Goethe Bach Schiller Room Goethe Bach Schiller
N: Dental materials B: Bio-nano materials S: Tissue engineering & D: Biodegradable materials B: Bio-nano materials S: Tissue engineering &
regenerative medicine regenerative medicine
Chair: C. Lüdecke-Beyer, Friedrich Chair: T.F. Keller, Deutsches Elektro- Chair: A.R. Boccaccini, University Chair: F. Witte, Charité-Universitäts- Chair: T.F. Keller, Deutsches Elektro- Chair: P. Kluger, FI Interfacial
Schiller University of Jena nen-Synchroton, DESY, Hamburg Erlangen-Nürnberg, (Germany) medizin Berlin, (Germany) nen-Synchroton, DESY, Hamburg Engineering & Biotechn., Stuttgart
09:40 Establishment and characte- Using nature s genius for Bioactive Glass Based Nano- 11:00 Coffee Break
rization of oral tissue cell the functionalization of sur- structured Scaffolds for Vas-
lines for biological investi- faces cularized Bone Tissue 11:30 Designed to Dissappear: Directed Assembly of Nano- EU ArtiVasc:Optimized cul-
gations of dental materials J. Raff (Sp), T. Günther, U. Weinert, Engineering New Bioresorbable Alloys particles to Isolated Diatom ture conditions for mature
B. Schminke (Sp), R. Bürgers, N. M. Vogel, M. Suhr, S. Matys, B. Dro- A.R. Boccaccini, University of Erlan- for Implants Valves Using the Non-Wet- adipocytes in 3D Adipose
Miosge, University Medical Center bot, K. Pollmann, Helmholtz-Zentrum gen-Nürnberg (Germany) W.-A. Heiß (Sp), C. Legner, U.E. ting Characteristics after Tissue Engineering
Goettingen, Göttingen (Germany) Dresden-Rossendorf (Germany) Klotz, Research Institute for Precious Pyrolysis B. Huber (Sp), E. Hoch, G. Tovar, Uni-
Metals and Metals Chemistry (fem), A. Jantschke (Sp), C. Fischer, Techni- versity of Stuttgart (Germany); K.
10:00 Influence of changing ion Dynamic Interfaces for Res- Decreased extrusion of cal- Schwaebisch Gmuend (Germany) sche Universität Dresden (Germany); Borchers, P. Kluger, Fraunhofer Insti-
composition on the protein ponsive Surface Encapsulati- cium-phosphate versus high R. Hensel, INM - Leibnis Institute for tute for Interfacial Engineering and
film formation on titanium on Systems S. Ulase- viscosity PMMA cement into New Materials, Saarbrücken (Ger- Biotechnology, Stuttgart (Germany)
F. Kratz (Sp), C. Müller-Renno, N. vich, Y. Zhukova, O. Baidukova, E. spongious bone marrow many); H.-G. Braun, Max Bergmann
Davoudi, University of Kaiserslautern Skorb (Sp), Max Planck Institute of may be suitable for the Center of Biomaterials, Dresden
(Germany); N. Umanskaya, S. Grass, Colloids and Interfaces, Potsdam reduction of adverse effects (Germany); E. Brunner, Technische
M. Hannig, University Hospital of the (Germany) L. Xin (Sp), V. Kopsch, S. Bischoff, J. Universität Dresden (Germany)
Saarland, Homburg (Germany); C. Adolph, H. Schubert, E. Kunisch,
Ziegler, University of Kaiserslautern R.W. Kinne, Uni. Hospital Jena,
(Germany) Eisenberg (Germany); M. Bungartz, 11:50 Development of resorbable Multiple Fluorophore EU ArtiVasc: New biodegra-
O. Brinkmann, Rudolf-Elle-Kranken- magnesium implants for the Doped, Photostimulable, dable polyurethane fleeces
haus, Eisenberg; S. Maenz, J. Bos- treatment of individual Fluorescent Silica Nanopar- as tissue engineering scaf-
sert, Univ. of Jena; B. Illerhaus, J. bone defects in oral and ticles for Intracellular Biolo- folds for adipose-derived
Günster, BAM Berlin maxillofacial surgery gical Imaging stem cells
O. Jung (Sp), P. Hartjen, H. Hanken, L. Treccani (Sp), S. Shahabi, K. M. Schnabelrauch (Sp), T. Laube, R.
10:20 Blue Light Emitting Diode Polymer Coated Nanodia- Structural and cellular chan- University Medical Center Hamburg- Rezwan, University of Bremen (Ger- Wyrwa, T. Walter, INNOVENT e.V.,
(LED) Photopolymerization monds Modified with Trans- ges of in a sheep model of Eppendorf (Germany); A. Kopp, C. many) Jena (Germany); A. Gugerell, J.
of Dental Materials – from ferrin as Highly Selective osteoporosis Ptock, Meotec GmbH & Co.KG, Kober, M. Keck, Medical University
History to State of the Art Fluorescent Probes T. El Khassawna (Sp), W. Böcker, D. Aachen (Germany); M. Heiland, R. of Vienna (Austria); S. Nürnberger,
K.D. Jandt, Friedrich Schiller Univer- J. Slegerova (Sp), M. Hajek, F. Sed- Weisweiler, D. Bürgener, L. Schröder, Smeets, University Medical Center Ludwig Boltzmann Institute for
sity of Jena (Germany) lak, I. Rehor, E. Kuzmova, P. Ciglerm A. Schlagenhauf, S. Widmann, A. Hamburg-Eppendorf Experimental and Clinical Traumato-
Institute of Organic Chemistry and Stärk, M. Kampschulte, C. Heiss, logy, Vienna; E. Grönniger, S. Brön-
Biochemistry AS CR, v.v.i., Prague Justus Liebig University of Giessen neke, Beiersdorf AG, Hamburg
(CZ); , J. Stursa, Nuclear Physics
Institute AS CR, Rez near Prague
12:10 Effect of Ag and Ca on Self-assembled protein EU ArtiVasc: Electrospun
10:40 Failure Behaviour and Relia- Nanostructured surfaces Heparin mimetic dendritic microstructure and phase nanofibers as basis for biodegradable polymers as
bility of Dental Bio-ceramics and cell behavior: Human Polyglycerolsulfate (dPGS) formation of Mg-2Gd alloy novel biomaterials matrix in adipose tissue
A. Märten (Sp), TU Berlin; R. Zehbe, Fibronectin within nano- based Hydrogels for Cartila- Y. Lu (Sp), Y. Huang, F. Feyerabend, C. Helbing, S. Maenz (Sp), C. engineering
C. Fleck, Berlin Institute of Technolo- wells ge Tissue Engineering R. Willumeit-Römer, K.U. Kainer, N. Lüdecke, Friedrich Schiller University N. Nottrodt (Sp), FI for Laser Techno-
gy; J. Forien, P. Zaslansky, C. Mocha- G.M.L. Messina (Sp), G. Marletta, P. Dey (Sp), R. Haag, Freie Univer- Hort, Helmholtz-Zentrum Geesthacht of Jena (Germany); T. Deckert-Gau- logy, Aachen; S. D’Aniello, L. Tamma-
les, W.-D. Mueller, Charité Berlin; A. University of Catania (Italy); A. Kara- sität Berlin; T. Schneider, G. Schultz- (Germany) dig, Institute for Photonic Technolo- ro, Univ. of Salerno, Fisciano, (Italy);
Rack, European Synchrotron Radiati- kecili, Ankara University (Turkey); Tanzil, Charité Berlin; L. Chiappisi, gy, Jena (Germany); K.D. Jandt, Frie- A. Gugerell, J. Kober, M. Keck, Medi-
on Facility, Grenoble (France) M.C. Yurtsever, M. Gümüt Dereliolu, M. Gradzielski, TU Berlin drich Schiller University of Jena (Ger- cal Univ. of Vienna (Austria); M.
Hacettepe University, Ankara many) Malin, J. Seppälä, Aalto University
(Finland)
16 17Wednesday, 22. April 2015 Wednesday, 22. April 2015
Lectures Lectures
Goethe Bach Schiller Goethe Bach Schiller
D: Biodegradable materials B: Bio-nano materials S: Tissue engineering & D: Biodegradable materials M: 3D printing / additive manu- G: Biointerfaces /microenviron.
Room regenerative medicine Room facturing of biomaterials L: challenges for MedTech Ind.
Chair: F. Witte, Charité-Universitäts- Chair: T.F. Keller, Deutsches Elektro- Chair: P. Kluger, FI Interfacial Chair: F. Feyerabend, Helmholtz- Chair: M. Pfaffinger, Vienna Universi- Chair: N. Stark, Biotronik AG,
medizin Berlin, (Germany) nen-Synchroton, DESY, Hamburg Engineering & Biotechn., Stuttgart Zentrum Geesthacht, (Germany) ty of Technology, (Austria) Bülach, (Switzerland)
12:30 In-situ high resolution AFM Single-molecule investigati- EU ArtiVasc:Optimizing the 14:15 Effect of magnesium degra- Selective Laser Melting of EU AmbuLung:Improving
studies of MgO-dissolution ons on DNA origami sub- supply performance of vas- dation products on mesen- magnesium alloys - A new blood-contacting polymeric
processes in aqueous elec- strates cularized artificial soft tissu- chymal stem cell fate and route towards manufactu- surfaces by bio-functional
trolytes A. Keller (Sp), C. Kielar, J. Rackwitz, es osteoblastogenesis ring individual and biodeg- modifications and endothe-
I. Giner (Sp), A. Keller, G. Grundmei- University of Paderborn (Germany); J. Courseau (Sp), R. Jaeger, Fraunho- B.J.C. Luthringer (Sp), R. Willumeit- radable implants lialization
er, Paderborn University (Germany) A. Rotaru, ‘Petru Poni’’ Institute of fer-Institute for the Mechanics of Römer, Helmholtz-Zentrum Geest- M. Gieseke (Sp), C. Nölke, S. Kaierle, A. Wenz (Sp), University of Stuttgart
Macromolecular Chemistry, Iasi Materials, Freiburg (Germany) hacht (Germany) Laser Zentrum Hannover e.V. (Ger- (Germany); K. Linke, M. Schandar, K.
(Romania); K.V. Gothelf, F. Besenba- many); H.J. Maier, Leibniz Universität Borchers, Fraunhofer Institute for
cher, Aarhus University (Denmark); Hannover (Germany); H. Haferkamp, Interfacial Engineering and Biotech-
G. Grundmeier, University of Pader- Laser Zentrum Hannover e.V. (Ger- nology IGB, Stuttgart (Germany); F.
born (Germany); I. Bald, University many) Metzger, E. Novosel, J. Schneider,
of Potsdam (Germany) Novalung, Heilbronn (Germany); P.
Kluger, Reutlingen University (Ger-
many)
12:50 Magnesium degradation in Detection of pathogenic Aerographite for tissue 14:35 Open porous Mg scaffolds EU ArtiVasc:Biobased Polyu- Osteoblastic cell behavior in
contact with blood bacteria with Electrochemi- engineering allow angiogenesis and rethane Elastomer for Blood titanium alloys with structu-
F. Feyerabend (Sp), Helmholtz-Zen- cal Impedance Spectroscopy C. Lamprecht (Sp), C. Grabosch, A. replacement by new bone Vessel Model by Stereo- red surface designed by
trum Geesthacht (Germany); B. (EIS) using bacteriophages Schuchardt, I. Paulowicz, Christian- formation lithography electron beam technique
Mihailova, University of Hamburg at a single-use graphite Albrechts-University Kiel (Germany); F. Witte (Sp), Charité - Universitäts- H.S. Le (Sp), M. Liikanen, M. Malin, C. Ramskogler (Sp), Graz University
(Germany); H.P. Wendel, University electrodes modified with M. Mecklenburg, K. Schulte, Techni- medizin Berlin (Germany); K. Bobe, H. Korhonen, J. Seppälä, Aalto Uni- of Technology (Austria); S. Mostofi,
Childrens Hospital, Tübingen (Ger- gold nanorods sche Universität Hamburg-Harburg Medizinische Hochschule Hannover versity, Espoe (Finland); J. Weisser, T. Medical University Graz (Austria); F.
many) F. Moghtader (Sp), Hacettepe Uni- (Germany); R. Adelung, C. Selhuber- (Germany); I. Morgenthal, O. Ander- Walter, M. Schnabelrauch, Innovent Warchomicka, Graz University of
versity, Ankara (Turkey); G. Congur, Unkel, Christian-Albrechts-University son, IFAM Dresden (Germany) e.V., Jena (Germany) Technology (Austria); A. Weinberg,
A. Erdem, Ege University, Izmir (Tur- Kiel (Germany) Medical University Graz (Austria); C.
key); E. Piskin, Hacettepe University, Sommitsch, Graz University of Tech-
Ankara (Turkey) nology (Austria)
14:55 Strong bioresorbable beta- Stereolithographic Additive EU AmbuLung:Clinical need
13:10 TCP-(Fe-Mg) nanocomposi- Manufacturing of Tricalcium for new biohybrid lung
- Lunch Break tes by attrition milling and Phosphate assist devices
14:15 high pressure consolidation M. Pfaffinger (Sp), G. Mitteramskog- G. Matheis (Sp), Novalung GmbH,
S.K. Swain (Sp), I. Gotman, E.Y. ler, Ö. Kaslioglu, J. Stampfl, Vienna Heilbronn (Germany); F. Bigazzi, G.
Gutmanas, Technion-Israel Institute University of Technology, Wien (Aus- Camiciottoli, University of Florence
of Technology, Haifa (Israel) tria) (Italy); J. Schneider, Novalung GmbH,
Heilbronn (Germany); M. Pistolesi,
-15.15 University of Florence (Italy)
18 19Wednesday, 22. April 2015
Lectures
Room Goethe Bach Schiller Round-Table Discussion: Current and future challenges for MedTech Industry
D: Biodegradable materials P: Imaging of biomaterials L: Current and Future challen- Introduction of the speakers:
ges for MedTech Industry
Chair: F. Feyerabend, Helmholtz- Chair: S. Maenz, Friedrch-Schiller Chair: N. Stark, Biotronik AG, ....continued from page 20.... biological principles to enhance the tis- Georg Matheis, Priv. Doz. Dr. med.
Zentrum Geesthacht, (Germany) University Jena, (Germany) Bülach, (Switzerland) sue-specific differentiation of embryonic Novalung GmbH, Heilbronn,
Thus radical change is inevitable and com- and adult stem cells towards pulmo- Germany
panies that embrace it will shape the indu- nary, cardiac and neuronal lineages. Dr. Georg Matheis has served as the Mana-
15:20 Bioglass Foam Scaffolds for Nanoscale Mechanical Map- EU AmbuLung: stry and benefit from their efforts. Since Lelkes has organized several Keystone ging Director for Novalung since the
Bone Reconstruction ping at a Wide Range of Bioartificial Devices for Car- each sector and company faces a different conferences, published more than 190 company's inception in 2003. He cofo-
L.-P. Lefebvre (Sp), S. Grenier, Natio- Deformation Rates With diac and Pulmonary Sup- set of headwinds, depending on the indivi- peer-reviewed papers, authored several unded the company, and has more than
nal Research Council Canada, Bou- Atomic Force Microscopy port- Past, Present and dual environment it is the goal of the dis- books and more than 50 book chapters 27 years of clinical, academic and ent-
cherville (Canada); V. Melli, E. Boc- A. Dulebo (Sp), Bruker, Karlsruhe Future cussion is to share challenges, insights and and made more than 400 presentations repreneurial experience in the medical
cardi, C. Catignoli, L. Altomare, L. De (Germany); B. Pittenger, C. Su, S. P. Lelkes, Temple University, Philadel- strategies across leaders in different indu- nationally and internationally. device and biotech sectors. Dr. Matheis
Nardo, Politecnico di Milano (Italy); Minne, Bruker, Santa Barbara, CA phia , PA (USA) stries. Furthermore we want to discuss Dr. Lelkes' basic and translational rese- founded, managed, and invested in
M. Cerruti, McGill University, Mon- (USA) with podium and audience how a healthy arch has been support by federal (NIH, several medical device and biotech
treal (Canada); E.A. Aguilar Reyes, B. Round Table Discussion - collaboration between industry and acade- NSF, NASA, DOE) and state funding companies, and served as medical direc-
Jacinto Diaz, University Michoacana Current & future challenges mia can ensure that both are well equip- agencies (NTI and PA Dept. of Commer- tor of Jostra AG prior to the founding of
de San Nicolás de Hidalgo, Morelia for the MedTech industry ped for the future. ce, Tobacco Settlement Funds) and pri- Novalung. He teaches at Goethe Uni-
(Mexico) With 5 percent average annual growth vate Foundations, including the Craig H. versity in Frankfurt where he served in
and operating margins above 20 per- Peter I. Lelkes, PhD Neilsen Foundation and the Coulter clinical and academic positions as a car-
15:40 Fabrication of Starch-g-PLA Characterization of three cent the medical device industry has Temple University, Philadelphia, Foundation. Dr. Lelkes has been the diac surgeon, and as a consultant for
Copolymers in Supercritical dimensional composite scaf- been stable and highly attractive for USA team leader for tissue engineering at medical device companies and inve-
Carbon Dioxide Medium folds - effect of vascular decades. As a consequence, established is the Laura H. Carnell Professor and the Nanotechnology Institute of Sou- stors. Dr. Matheis holds Dr. med.
F. Moghtader (Sp), E. Piskin, K. Sali- prefabrication on angioge- players were able to successfully com- Founding Chair of the Department of theastern Pennsylvania (NTI) and is the (summa cum laude) and Associate Pro-
mi, M. Yilmaz, Z.M.O. Rzayev, Hacet- nesis pete without much need for differen- Bioengineering in the College of Co-Director of PATRIC, the Pennsylvania fessor (Privatdozent) degrees from
tepe University, Ankara (Turkey) K. Szlazak (Sp), J. Jaroszewicz, B. tiation. But disruptive change is under- Engineering at Temple University. Dr. Advanced Textile Research and Innovati- Goethe University at Frankfurt, and a
Ostrowska, J. Idaszek, W. Swieszko- way. Companies will no longer get pre- Lelkes is also the Inaugural Director of on Center, focusing on BioNanoTextiles Prof. h.c. from FAMEMA Marilia, Sao
wski, Warsaw Univ. of Techn. (PO); T. mium reimbursement by simply selling the Institute for Regenerative Medicine and Stem Cell Biology. Paulo. His career includes positions at
Debski, Med.Centre of Postgraduate clinical features and new devices in and Engineering (TIME) at Temple Uni- Dr. Lelkes has received numerous UCLA, Freiburg University and Goethe
Education, Warsaw; J. Wysocki, Z. established markets. Furthermore cen- versity's School of Medicine and Profes- honors and awards, nationally and University in Frankfurt. He is a distin-
Pojda, Marie Sklodowska-Curie Can- tralized purchasing based on compara- sor for Cancer Biology at the Fox Chase internationally. Amongst them a Forch- guished speaker, lecturer, and editor,
cer Memorial Centre, Warsaw tive value and evidence of efficacy will Cancer Center. Prior to that he was heimer Visiting Fellowship at the Hebr- and is the author of numerous peer-
change the commercial model. A.T. from 2000-2011 the Calhoun Chair ew University, Jerusalem, Honorary Pro- reviewed scientific articles.
Kearney together with executives from Professor in the School of Biomedical fessorships at the University of Applied
16:00 Biodegradable microelectro- Atomic Force Microscope- leading medical device manufacturers Engineering, Science and Health Sciences Aachen, Germany and the
des to deposit a viable coupled Infrared Spectrosco- identified their five major disruptors Systems at Drexel University in Philadel- Changchun Institute of Polymer Chemi-
structured cell-protein layer py for sensing ultra-thin shaping current and future medical phia with adjunct appointments in the stry and Physics, Chinese Academy of
F. Schmidt (Sp), R. Zehbe, C. Fleck, biomaterial device industry. Departments of Mechanical Engineering Sciences, and a Distinguished Visiting Dr. Claude Rieker
TU Berlin (Germany); U. Gross, Freie A. Deniset (Sp), A. Dazzi, Universite and Mechanics (College of Engineering) Fellowship of the Royal Academy of Director Scientific Affairs -
Universität Berlin (Germany); O. Paris-Sud, Orsay (France); C. Mar- 1. Power shift to payers and providers and Pathology, Biochemistry and Sur- Engineering at Imperial College, Lon- Zimmer GmbH, Winterthur,
Görke, TU Berlin (Germany) cott, Light Light Solutions, Athens, 2. Heightened regulatory scrutiny gery (College of Medicine). Currently don, UK. In 2011 he was inducted as a Switzerland
GA (USA); K. Kjoller, M. Lo, E. Dillon, 3. Unclear sources of innovation Prof. Lelkes directs a broad interdiscipli- Fellow of the AIMBE (American Institute After having studied material sciences
R. Shetty, Anasys Instruments Corp, 4. New healthcare delivery models nary program in regenerative tissue for Medical and Biological Engineering) at the Swiss Institute of Technology in
Santa Barbara, CA (USA); T. Gross, 5. Need to serve lower socioeconomic engineering, focusing on nanotechnolo- and received the 2012 Ben Franklin Key Lausanne (EPFL), Claude Rieker studied
Phi Europe GMBH, Munich classes gy-based biomaterials and soft tissue Award from IEEE, the Institute of Elec- the rapid solidification of stainless
....please follow page 21..... engineering, employing developmental trical and Electronics Engineers. steels at the University of Neuchâtel
16:20 Announcement of the Posteraward and Closing address,
K.D. Jandt and T.F. Keller, Chairmen of the Conference
16:40
20 21Tuesday 21. April through Wednesday 22. April
Oralposter and Poster
Round-Table Discussion: Current and future challenges for MedTech Industry
A: Antimicrobial
Introduction of the speakers: biomaterials & biofilms
and obtained his PhD in 1990 from this a Johnson & Johnson company. From and Glass-ceramics (Chap. 12) in the
A-44 Thermally sprayed calci- A-117 Antimicrobial surfaces A-203 Preparation of Mutiva-
university. He started to work in ortho- 1997 to 2011 he served in R&D roles of book “Advanced Ceramics for Denti-
paedics immediately after his PhD, desi- increasing responsibility for Sulzer stry”, Elsevier, edited by James Shen. He um phosphate coatings with release properties lent Surface Coatings of
gning hip implants and working closely Medica, which in 2003 became acqui- was educated in France and Sweden, with antibacterial pro- for dental implants J. Phosphoryl Choline on
with key European surgeons like M.E. red by Zimmer. During this time he and received his PhD in Materials Che- perties Barz, Fraunhofer Institu- PTFE Surfaces
Müller, H. Wagner, E. Morscher, and L. initiated the project and secured fun- mistry in 2005 from the University of P. Krieg (Sp), University of Stutt- te for Interfacial R. Hammer (Sp), PVA tePla AG,
Spotorno. From 1995 to 2006, Claude dings to develop the first implantable Lund where he was conducting research gart (Germany); A. Bernstein, Engineering and Bio- Prien (Germany); M. Barden,
Rieker had the global responsibility of human knee joint with force sensors to in injectable calcium phosphate bone University of Freiburg (Ger- technology (Germany); PVA tePla America, Corona
all research activities in tribology for measure joint loads of patients in vivo, substitutes for orthopedic applications. many); A. Killinger, R. Gadow, M. Bach (Sp), University of (USA)
Sulzer / Zimmer and developed / optimi- a collaboration with the Charitè Hospi- He also holds an education and wor- University of Stuttgart (Ger- Stuttgart (Germany); R. Bürgers,
zed all the bearings within the portfolio tal. It was followed by a two-year inter- king experience in International Sales & many) Universitätsmedizin Göttingen
of Sulzer / Zimmer. During these 11 national work assignment at Zimmer's Marketing. (Germany)
years of research, Claude Rieker gained headquarter in the US, where he was
extensive knowledge on hard-on-hard responsible for formulating and develo-
bearings, on highly cross-linked poly- ping a product strategy for drug-device-
ethylene technologies, and also on all combination products across Zimmer's Norman Stark A-52 Nano and macro porous A-176 Bacterial adhesion on
tribologic aspects of total joint arthro- product portfolio. Manager Strategic Projects R&D - membranes á la carte nanorough titanium:
plasties. The key results of these activi- Biotronik AG, Bülach, Switzerland M. Lelonek (Sp), M. Lelonek, Preliminary insight into
ties have been published in peer-revie- Mr. Klabunde holds a MSc in Biomedical After starting his career in medical SmartMembranes GmbH, Halle the nanostructure of the
wed journals. For the last 9 years, Clau- Engineering from the University of Industry with Zimmer in 2005 he served (Germany) microbe-material-interfa-
de Rieker has the responsibility of the Rostock and an MBA in General Mana- as Manager of the Polymer Research ce and adhesion mecha-
European Scientific Affairs for Zimmer. gement from the University of St. Gal- Group before taking over extended res- nisms
len. ponsibility for the Metals, Processes and C. Lüdecke-Beyer (Sp), Friedrich
Retrieval analysis teams and laborato- Schiller University Jena (Ger-
ries. In his functions he supported and A-82 Development of nano- many); M. Roth, Bio Pilot Plant,
led various important new technology porous titanium dioxide Leibniz Institute for Natural Pro-
Dr. Simon Jegou, and process optimization projects and surfaces with antimicro- dukt Research and Infection
Divonne-les-Bains, France authored and coauthored numerous bial activity for control- Biology, Jena (Germany); J. Bos-
Dr. Simon Jegou is an expert in ceramics publications and patents. Since 2014 led drug delivery sert, K.D. Jandt, Friedrich Schil-
Ralf Klabunde and ceramic processing technologies, Norman is leading task forces and systems in dental appli- ler University Jena (Germany)
VP Engineering - specializing in ceramics for medical major projects as a Strategic R&D Pro- cations
icotec AG, Altstätten, Switzerland applications. He has more than 8 years ject Manager for Biotronik AG in Swit- P. Abendroth (Sp), Leibniz Uni-
Mr. Klabunde brings close to 20 years international experience in the Medical zerland. Besides his responsibilities wit- versität Hannover (Germany); K.
of experience and leadership in the Device Industry occupying management hin Biotronik he serves as an active Doll, J. Schaeske, Hannover A-177 Microbial adhesion on
medical device industry to his current roles in both R&D and Sales and Marke- member of the German Society for Bio- Medical School; H. Fullriede, physically nanostructu-
role. At icotec he is leading icotec's ent- ting. He worked the past 6 years at materials, the European Society for Bio- Leibniz Universität Hannover; A. red biomaterials surfaces
ire product development functions to Nobel Biocare managing and driving materials and the ESB Educational Winkel, M. Stiesch, Hannover C. Dewald (Sp), C. Lüdecke, Frie-
apply icotec's high strength, continuous Research and Early Development projec- Committee. Norman holds a Master in Medical School; P. Behrens, drich Schiller University Jena
fiber composite technology to medical ts within the field of ceramic-based Engineering with a major in biomateri- Leibniz Universität Hannover (Germany); M. Roth, Bio Pilot
devices (trauma and spine) and to high prosthetic and implant treatment soluti- als and a Master in Business Admini- Plant, Leibniz Institute for Natu-
performance industrial applications, ons, in collaboration with universities, stration focusing on leadership and ral Produkt Research and Infec-
such as in automotive and aerospace. industry, and leading clinicians and human capital management. tion Biology, Jena (Germany); J.
Before joining icotec in 2014, he held technicians. He has authored several Bossert, K.D. Jandt, Friedrich
responsibility for the EMEA product scientific papers and patent applicati- Schiller University Jena (Ger-
development functions of DePuy Spine, ons, and a chapter on Dental Glasses many)
22 23Tuesday 21. April through Wednesday 22. April Tuesday 21. April through Wednesday 22. April
Oralposter and Poster Oralposter and Poster
B: Bio-nano materials C: Bioactive materials
B-26 Ionic liquid-assisted for- B-89 Nanoscale Imaging and B-136 Ultrathin biocompatible C-5 Spin-coated and dip-coa- C-86 Biocomposites for tooth C-118 Chemical and Morpholo-
Oral mation of cellulose/calci- Oral Quantitative Nanome- coatings of fluorescent ted calcium hydroxyapa- regeneration based on Oral gical Changes of
Poster um phosphate hybrid Poster chanical Characterization diamonds tite thin films on titani- collagen matrix, nano- Poster hydroxyapatite Cold Gas
materials with potential of Biomaterials by Ato- J. Vavra (Sp), I. Rehor, P. Cigler, um, silicon and quartz porous silica nanopar- Spray coatings during
application as biomateri- mic Force Microscopy Academy of Sciences of the substrates: preparation ticles and bone morpho- Immersion in Simulated
als T. Müller, D. Stamov, J. Barner, T. Czech Republic, Prague (Czech and characterization genetic proteins (BMPs) Physiological Solutions
A. Salama, A. Taubert (Sp), Uni- Henze, F. Kumpfe, C. Pettersson Republic) M. Malakauskaite-Petruleviciene A. Satalov (Sp), P. Behrens, Leib- A. Martín Vilardell (Sp), N.
versity of Potsdam, Golm (Ger- (Sp), T. Jahnke, JPK Instruments (Sp), Z. Stankeviciute, A. niz Universität Hannover (Ger- Cinca, A. Concustell, S. Dosta,
many) AG, Berlin (Germany) Prichodko, A. Kareiva, Vilnius many); M. Steindorff, E. Geller- I.G. Cano, J.M. Guilemany, Uni-
Development of University (Lithuania) mann, H. Hartwig, A. Winkler, versity of Barcelona (Spain)
B-155
Engineered Iron-Oxide M. Stiesch, Hannover Medical
Oral
Round diamond nano- Carbon Nanotube Coa- Poster Nanoparticles by Lentivi- School (Germany)
B-58 B-101
particles tings on Electrodes for ral Vectors for Target
H. Raabova (Sp), IOCB AS CR, Neural Interface Applica- Cancer Therapy and C-21 Morphological patterns C-120 Structuring surfaces of
Prague (Czech Republic); I. tions Hyperthermia Oral in the micrometer and Oral bioactive glasses at the
Poster
Rehor, IOCB AS CR, Prague N. Burblies (Sp), K. Kreiskoether, E. Borroni (Sp), E. Catalano, A. Poster nanometer range to C-90 Plasma spraying as a micro scale by mould
(Czech Republic); P. Cigler, IOCB H.-C. Schwarz, P. Behrens, Leib- Cochis, F. Oltolina, M. Prat, L. influence biological res- Oral tool for the generation casting
AS CR, Prague (Czech Republic) niz Universität Hannover (Ger- Rimondini, University of Pie- ponse to titanium based Poster of bioactive surfaces B. Pföss (Sp), RWTH Aachen
many); J. Schulze, K. Kranz, K. monte Orientale, Novara (Italy); substrates H. Testrich (Sp), A. Quade, A. University (Germany); M. Höner,
Wissel, A. Warnecke, Hannover S. Ferraris, M. Miola, E. Vernè, M.M. Subhani (Sp), X. Wang, R. Kruth, M. Fröhlich, K.-D. Welt- University Hospital RWTH
Medical School (Germany) Politecnico di Torino, Turin Hess, D. Langheinrich, R. Beut- mann, M. Polak, Leibniz Institu- Aachen (Germany); M. Wirth, T.
B-65 Fabrication and SERS (Italy); S. Novek, Jo√ef Stefan ner, A.-F. Lasagni, D. Scharnewe- te for Plasma Science and Tech- Vossel, RWTH Aachen University
Applications of Uni- Institute, Ljubljana (Slovenia); A. ber, Technische Universität Dres- nology, Greifswald (Germany) (Germany); H. Fischer, University
directional Gold and Sil- Follenzi, den (Germany) Hospital RWTH Aachen (Ger-
ver Nanorod Arrays B-103 Nanoporous Platinum many); A. Bührig-Polaczek, R.
Enhanced by Colloidal Coatings for Electrodes PEG-based Hydrogels Conradt, RWTH Aachen Univer-
B-175
Nanoparticles in Biomedical Applicati- Surface Patterned with C-111 Investigation of bio- sity (Germany)
E. Piskin (Sp), G. Demirel, E. ons Gold Nanoparticles for C-66 In vitro effects of Cu- glass-ceramics contai-
Piskin, Hacettepe University, K.D. Kreisköther (Sp), K. Kranz, Selective Immobilization doped 45S5 bioactive ning natural bones
Ankara (Turkey) K. Wissel, J. Schulze, P. Behrens, of Biomolecules glass and lipid peroxida- A. Dobrádi (Sp), M. Enisz-Bódo-
Leibniz Univerisität Hannover C. Yesildag (Sp), Z. Zhang, M.C. tion on the growth of gh, K. Kovács, University of Pan- Design of functionalized
C-140
(Germany) Lensen, TU Berlin (Germany) human osteoblast-like nonia, Veszprém (Hungary) beta-TCP spray-dried
Gold Decorated Magne- cells granules for HVOF ther-
B-69
tite Nanoparticles as a L. Milkovic, Rudjer Boskovic mal spray applications
Oral
Non-viral vector Applied Institute, Zagreb (Croatia); A. I. Arhire (Sp), A. Killinger, R.
Poster
in Cell Cultures on B-119 Nanodiamonds surface Hoppe, T. Zehnder, J. Will, R. Gadow, University of Stuttgart
Tumor Cell Lines design – particle jigsaw Detsch, University of Erlangen- (Germany)
D.D. Usta, Hacettepe University, in solution Nürnberg (Germany); N. Zarko-
Ankara (Turkey); M. Turk, Kirik- J. Havlik (Sp), Academy of Scien- vic, Rudjer Boskovic Institute,
kale University (Turkey); E. ces of the Czech Republic, Pra- Zagreb; A.R. Boccaccini (Sp),
Piskin (Sp), Hacettepe Universi- gue (Czech Republic); P. Cigler, University of Erlangen-Nürnberg
ty, Ankara (Turkey) Academy of Sciences of the (Germany)
Czech Republic, Prague (Czech
Republic)
24 25Tuesday 21. April through Wednesday 22. April Tuesday 21. April through Wednesday 22. April
Oralposter and Poster Oralposter and Poster
C: Bioactive materials D: Biodegradable F: Bioinspired Materials G: Biointerfaces / H: Biological materials
materials microenvironments
C-143 Development and activi- D-25 Toughening of porous D-106 Effect of Morphology on F-14 Assembly and Structure G-161 The micro-porous blood H-75 Biogenic Wood Plastic
ty of human osteoclast bioceramic scaffolds by Oral Ageing Characteristics of Oral of Spider Silk Nano- contact surface manufac- Oral Composites from bio-
cells on 45S5 bioactive bioresorbable polymeric Poster Poly(Lactic Acid) in Diffe- Poster Fibrils tured on titanium by Poster based Polyamide 11 and
glass coatings rent Media M. Humenik (Sp), T. Scheibel, glow-discharge assisted chemically modified
R. Detsch, A.R. Boccaccini (Sp), S. Dorozhkin, Moscow (Russian K. Bruckmoser (Sp), K. Resch, University of Bayreuth (Ger- nitriding process for Beech Fibers
A. Hoppe, A. Grünewald, Uni- Federation) University of Leoben (Austria) many) application in the rotary P. Zierdt (Sp), S. Wittchen,
versity of Erlangen-Nürnberg blood pump elements Fraunhofer Institute for Mecha-
(Germany); E. Strasser, P. Steini- M. Gonsior (Sp), R. Kustosz, M. nics of Materials IWM, Halle
ger, University Hospital Erlangen D-38 Hydration of partially D-121 Establishment of a new F-78 New biomaterials based Darak, I. Altyntsev, M. Kocielni- (Germany); A. Weber, Institut für
(Germany) Oral amorphized Sr2+ Oral method to quantify the Oral on self-folding films ak-Ziemniak, M. Gawlikowski, Holztechnologie Dresden (Ger-
Poster - containing alpha- TCP Poster immune cell response to Poster L. Ionov, Leibniz Institute of Foundation for Cardiac Surgery many); H. Costard, Flasin
powder samples subcutaneously or intra- Polymer Research Dresden (Ger- Development, Zabrze (Poland); GmbH, Neu Wulmstorf (Ger-
K. Hurle (Sp), M. Goebbels, J. musculary implanted many) T. Wierzcho, Warsaw University many)
C-202 Development and eva- Neubauer, F. Goetz-Neunhoeffer, materials of Technology (Poland)
Oral luation of 45S5 bioactive Friedrich-Alexander-Universität F. Witte (Sp), T. Schmidt, Z.
Poster glass based scaffolds Erlangen-Nürnberg (Germany) Kronbach, M. Heinze, M. Gei- F-107 Hydroxyapatite composi- H-129 A combined nanoinden-
coated with selenium ling, S. Krummsdorf, Charité - te cryogels as potential G-204 EU AmbuLung: Oral tation and finite ele-
nanoparticles or with Universitätsmedizin Berlin (Ger- scaffolds for tissue Biofunctionalization of Poster ment study of the bio-
poly(lactide-co-glycoli- D-56 Polarization measure- many) engineering PMP fibres for endothe- mechanics of Passiflora
de)/selenium nanopar- Oral ments with rotating disk S. Oehmichen (Sp), A. Prager, R. lialized gas exchanger discophora attachment
ticles Poster electrode for characte- Konieczny, N. Schönherr, I. Rein- membranes pads
A.R. Boccaccini (Sp), University rization of the degrada- D-124 Processing of Zn based hardt, S. Reichelt, Leibniz Insti- K. Borchers, Fraunhofer Institute C. Bos (Sp), R. Kappel, O. Kraft,
of Erlangen-Nürnberg (Ger- tion of Mg-Gd and Mg- Oral alloy tubes for biodegra- tute of Surface Modification, for Interfacial Engineering and R. Schwaiger, Karlsruhe Institute
many); M. Stevanovic, N. Filipo- Ag binary alloys Poster dable stent applications Leipzig (Germany) Biotechnology, Stuttgart (Ger- of Technology, Eggenstein-Leo-
vic, Serbian Academy of Science I. Marco (Sp), KU Leuven (Belgi- E. Mostaed (Sp), M. Hashem- many) poldshafen (Germany)
and Arts, Belgrade (Serbia) um); F. Feyerabend, R. Willu- pour, M. Sikora-Jasinska, M.
meit-Römer, Helmholtz-Zentrum Bestetti, Politecnico di Milano F-127 3D-Printing of bio-inspi-
Geesthacht (Germany); O. Van (Italy); A. Tuissi, National Rese- Oral red anti-reflective nano- H-169 Irradiated human dentin
der Briest, KU Leuven (Belgium) arch Council, Milan (Italy); M. Poster structures Oral reveals structure-toug-
Vedani, Politecnico di Milano J. Purtov (Sp), E. Kroner, Leibniz- Poster hness relations in teeth
(Italy) Institute for New Materials, A. Märten (Sp), J. Seddig, C.
D-92 Biodegradable Mg-alloys Saarbrücken (Germany) Fleck, TU Berlin (Germany); P.
Oral implants in a short-term Zaslansky, Charité-Universitäts-
Poster study D-178 Controlling the interfaci- medizin Berlin (Germany)
A. Myrissa (Sp), Medical Univer- Oral al strength in PLGA fiber
sity of Graz (Austria); G. Poster reinforced brushite
Szakács, Helmholtz-Zentrum cements H-185 Potentials of biological
Geesthacht, Hamburg (Ger- S. Maenz (Sp), M. Henning, M. Oral waste products for the
many); E. Martinelli, J. Eichler, S. Mühlstädt, Friedrich Schiller Poster reinforcement of poly-
Srinivasaiah, U. Schäfer, A.M. University of Jena (Germany); E. mer materials
Weinberg, Medical University of Kunisch, R.W. Kinne, Waldkran- J. Kaufhold (Sp), S. Geller, C.
Graz (Austria) kenhaus “Rudolf Elle“, Eisen- Läßig, M. Gude, TU Dresden
berg (Germany); J. Bossert, K.D. (Germany)
Jandt, Friedrich Schiller Universi-
ty of Jena (Germany)
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