HOW CAN GOOD RESULTS BE EVEN BETTER? - (Part 1) - RCPCH

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HOW CAN GOOD RESULTS BE EVEN BETTER? - (Part 1) - RCPCH
THE SAHLGRENSKA ACADEMY

HOW CAN GOOD RESULTS BE EVEN BETTER?
(Part 1)
NATIONAL PAEDIATRIC DIABETES AUDIT
ANNUAL CONFERENCE 2020, JANUARY 17
HOLIDAY INN, REGENTS PARK

GUN FORSANDER, ASSOCIATE PROF
THE QUEEN SILVIA CHILDRENS HOSPITAL
SAHLGRENSKA UNIVERSITY HOSPITAL
GOTHENBURG SWEDEN
HOW CAN GOOD RESULTS BE EVEN BETTER? - (Part 1) - RCPCH
THE SAHLGRENSKA ACADEMY

DISCLOSURE

I HAVE RECEIVED LECTURE HONORARIES FROM LILLY, NOVO NORDISK, SANOFI, RUBIN-MEDICAL
HOW CAN GOOD RESULTS BE EVEN BETTER? - (Part 1) - RCPCH
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Examples of ongoing work to improve quality of
pediatric diabetes care …

• Internationally; Sweet Study, ISPAD
• Nationally; Swediabkids, IQ-project
• Locally; Policy paper, the Angered
  project

                  Picture: Edvard Munch
HOW CAN GOOD RESULTS BE EVEN BETTER? - (Part 1) - RCPCH
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Common treatment targets for a child with diabetes

• A high quality of life - both now
  and for the future
• Normal mental and physical
  growth

• No DKA and severe
  hypoglycaemia
• No long-term complications
HOW CAN GOOD RESULTS BE EVEN BETTER? - (Part 1) - RCPCH
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Were all the problems solved one hundred years ago
when the access to insulin treatment appeared?

• A lack of insulin is still globally the most common reason behind
  death in children with diabetes
• Insulin is no cure, only a life-supporting treatment
• During the decades after introducing insulin treatment 1922, the
  complications of the disease were shown
• The question araised: does the way how the insulin treatment is
  implemented influence the risk for cardiovascular
  complications?
HOW CAN GOOD RESULTS BE EVEN BETTER? - (Part 1) - RCPCH
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Complications must be avoided-
also of monitary reasons:

• Diabetes complications causes at least 80 % of the diabetes
  related costs in society

       … must more than insulin, CGM, insulin pumps etc…
HOW CAN GOOD RESULTS BE EVEN BETTER? - (Part 1) - RCPCH
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                                                                                                                             )

Summary of consensus definitions
Diabetes Care 2017 Dec; 40(12): 16221630. https://doi.org/10.2337/dc17-1624

Outcome                                                                               Definition

                                                              Level 1: glucose 250 mg/dL
                                                              (13.9 mmol/L)

                                                              Percentage of readings in the range of 70–180 mg/dL
Time in range
                                                              (3.9–10.0 mmol/L) per unit of time
Time in target                                                3.9-7.8 mmol/l (70-140 mg/dl)

                                                              Elevated serum or urine ketones (greater than the upper
DKA                                                           limit of the normal range) and serum bicarbonate
HOW CAN GOOD RESULTS BE EVEN BETTER? - (Part 1) - RCPCH
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   Well and insufficiently controlled patients
   all centres, 01/01/2018 - 31/12/2018

- the width of the bubble represents the size of the centre
- yellow bubble: your center
- minimum requirement: 50 patients
                                                                                8
HOW CAN GOOD RESULTS BE EVEN BETTER? - (Part 1) - RCPCH
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          HbA1c: standard, median of patients’ medians
          T1DM, 0-18y, 01/01/2018 - 31/12/2018

STANDARDIZED:
mathematical correction of the HbA1c-values: HbA1cSTANDARDIZED = (HbA1c-RAW / mean HbA1c of your lab-
method) x 5
Median of patients’ medians: first calculate the median per patient per period, then the median of these medians
Number of patients must be at least 20 for being displayed.
                                                                                                                                     9
HOW CAN GOOD RESULTS BE EVEN BETTER? - (Part 1) - RCPCH
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            BMI-SDS: T1DM, patients 0-18y, WHO 2007reference
            01/01/2018 - 31/07/2018

                                                                                                                       10

N = number of patients with a calculated BMI standard deviation score(SDS)
Based on the mean of the patient’s medians (every patient with a calculated SDSvalues contributes with onemedian.
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Some national Swedish diabetes
quality initiatives and results
Painting by E Munch
Swedish National Pediatric
Diabetes Registry

• Incidence of type 1 diabetes is 45/100 000 in children below 18 years
  of age

• Second highest incidence in the world

• Almost everyone diagnosed with diabetes is included in the registry

• All 42 pediatric clinics that treat children with diabetes report data
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https://swediabkids.ndr.nu
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The Button A push   of a button for improvement
         work                   NDR.nu
                               ”Knappen”

                                   The Button
                                with results from
                                 all of Sweden
HbA1c ≤ 6.5%   HbA1c ≤ 6.6-6.8%      HbA1c ≤ 6.9-7.3%   HbA1c ≤ 7.4-8.6%   HbA1c > 8.6%
                             ISPAD 2019 Karin
ISPAD 2019 Karin Åkesson
%                            Proportion CGM users, %

                           Age
Proportion pump users, %
%

    Age
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Effective team work

          Study of Swedish pediatric diabetes clinics via
• Higher compliance with guidelines
•                                  SWEDIABKIDS
    Clear message of lower HbA1c-goal
• Well functioning teams

     Five centers were selected:
• Lower proportion of diabetes specialist educated team members …
•    lowest/
    Shorter       highest/largest
            professional working time … decrease center regarding mean value
•    of HbA1c
    Engaged   team members with a positive attitude

• Higher mean insulin dose
     Team members were asked to fill out questionnaires:
• Larger diabetes center
     Structure, Process and Policy
• “Team members’ policy and approaches affect glycaemic control in children and adolescents.
  Team members need to be aware of their approach and of the importance of using resources
  within the team”.

                                        L Hanberger, Diabetes Res Clin Pract, 2012
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Insulin dose
Compliance to guidelines at HbA1c levels                                      Process
above target value

Centre size
Team size
                                                                              Structure
Years of diabetes experience
Specific diabetes education

HbA1c target value                                                              Policy

 The national Swedish HbA1c target at the time of the study was
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 Effective team work with lower HbA1c values were
 characterized by:

• Higher compliance with guidelines
• Clear message of lower HbA1c-goal
• Well functioning teams

• Shorter professional working time (!)
• Engaged team members with a positive attitude

   ISPAD 2019 Karin Åkesson   L Hanberger, Diabetes Res Clin Pract, 2012
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As a consequence of this study, a new national project was
launched …

                    … The IQ-project!
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             Improving the quality of Swedish pediatric diabetes care

•   Initiative taken by the steering group of SWEDIABKIDS
•   Improvement would be reached by changes in work processes and not by an increased
    work load

              Peterson A, PLoS One 2014;9:e97875.
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              Improving the quality of Swedish pediatric diabetes care

•   Initiative taken by the steering group of SWEDIABKIDS
•   Improvement would be reached by changes in work processes and not by an increased
    work load

•   Learning sessions included lectures on improvement methods, teamwork and learning,
    and sharing data and ideas
•   In the intervals between the learning sessions, the team identified problems and
    improvement areas at their centres, created action plans, tested effect of changes, and
    followed up on the results

              Peterson A, PLoS One 2014;9:e97875.
THE SAHLGRENSKA ACADEMY
              Improving the quality of Swedish pediatric diabetes care

•   Initiative taken by the steering group of SWEDIABKIDS
•   Improvement would be reached by changes in work processes and not by an increased
    work load

•   Learning sessions included lectures on improvement methods, teamwork and learning,
    and sharing data and ideas
•   In the intervals between the learning sessions, the team identified problems and
    improvement areas at their centres, created action plans, tested effect of changes, and
    followed up on the results

•   Outcome variables were clinical, and included HbA1c, severe hypoglycemia
    (unconsciousness, seizures) and DKA
•   The process measures were documentation of smoking habits and the degree of physical
    activity

              Peterson A, PLoS One 2014;9:e97875.
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                           IQ project

                              LM = Lunch Meeting, PM = Phone Meeting

ISPAD 2019 KARIN ÅKESSON                                               Peterson A et al, PLOS, 2014
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          Tools

•   Problem inventory

•   5P (Purpose, Patients, People, Process, Patterns)
•   Clinical value compass                              Changes that
                                                        lead to
• Flow charts                                           improvements

• Activity plans
•   PDSA-wheel
    (Plan, Do, Study, Act)

• 12-14 diabetes teams at
  each course
                                Ideas, theories
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                        Fishbone diagram used in the IQ project
                                                            External collaboration
                                  Staff

    Structure of team meetings                    Day care / School

  Attitudes to the team work                            Social service

   Large turnover of dieticians                         Child Psychiatry

     Vague guidelines from the team                               Pharmacy
 Update of local policies and guidelines
            Insufficient education of the staff                                                                           Decrease
                                                                                                                          HbA1c
    Different ability to cope                  The patients
    with the disease                           lack tools                           100 /500-rule
 Unmotivated to meet                   Education about                     Clarify the leadership of
 with dietitian                        late complications                  the team
     Forgets insulin               More pumps                         Revise the care plan?
     doses                                                                                             Clarify the care plan for the patient
                              Talk about blood glucose,               Adherence to
Too few blood
                              not HbA1c!                              the care plan?
glucose tests
 Age                     Group meeetings

            Patient                            Self-care                               Care plan
                                          Patient education
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What were the project ideas of the individual teams
about?

  Examples:
  • Frequent visits if high HbA1c
  • Carbohydrate counting from onset
  • Increased use of CGM and pumps
  • Increase the proportion of patients with
      HbA1c < 57 mmol/mol
  • Reduce proportion HbA1c > 70 mmol/mol
  • Lowering target HbA1c to < 52 mmol/mol
  • No increase in severe hypoglycemia

        Peterson A, PLoS One 2014;9:e97875.
       Samuelsson U. Pediatric Diabetes 2016
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