MARIJUANA AND TEENS IN 2016 - DANIELLE RAMO, PHD ASSISTANT PROFESSOR IN RESIDENCE - PARENTS ...

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MARIJUANA AND TEENS IN 2016 - DANIELLE RAMO, PHD ASSISTANT PROFESSOR IN RESIDENCE - PARENTS ...
Marijuana and Teens in 2016
             Danielle Ramo, PhD
             Assistant Professor In Residence
                Department of Psychiatry
           University of California, San Francisco
                 Danielle.ramo@ucsf.edu

    Parents’ CoaliAon of Bay Area High Schools
                 February 1, 2016
MARIJUANA AND TEENS IN 2016 - DANIELLE RAMO, PHD ASSISTANT PROFESSOR IN RESIDENCE - PARENTS ...
Outline

•   Trends in marijuana use
•   Consequences of teen marijuana use
•   Current legal landscape
•   How parents can help
•   Scenarios and quesAons
MARIJUANA AND TEENS IN 2016 - DANIELLE RAMO, PHD ASSISTANT PROFESSOR IN RESIDENCE - PARENTS ...
US: Past Month Use
                                             2014 Monitoring the Future Survey
                                                 8th grade         10th grade       12th grade
                   40            37
                   35

                   30
% Past month use

                   25       24                   24
                                                                  21
                   20                                                                                       17
                                                             17
                   15                                                                         14
                                            11
                   10   9                                                                           9
                                                                            7             7                              8
                                                        7                                               6            6
                                                                        4             4                          3
                   5                    3                                       3

                   0
                        Alcohol       Been drunk Marijuana             SyntheAc     CigareYe E-cigareYes         Other
                                                                       marijuana              (Johnston  et al,et2014)
                                                                                                      Johnston    al., 2014
MARIJUANA AND TEENS IN 2016 - DANIELLE RAMO, PHD ASSISTANT PROFESSOR IN RESIDENCE - PARENTS ...
Past Month Marijuana Use by Age:
                             2002-2014 Na6onal Survey on Drug Use and Health

                        Age 12 or older    Age 12 to 17     Age 18 to 25       Age 26+
                   20
                   18
                   16
% Past Month Use

                   14
                   12
                   10
                   8
                   6
                   4
                   2
                   0

                                                                               SAMHSA, 2015
MARIJUANA AND TEENS IN 2016 - DANIELLE RAMO, PHD ASSISTANT PROFESSOR IN RESIDENCE - PARENTS ...
Daily or Near-Daily Cannabis Use Increasing
                                                2002-2012 NSDUH

                      9

                      8

                      7
Numbers in Millions

                      6

                      5

                      4
                                                                            Used Marijuana in 20 or
                      3                                                     More Days in the Past
                                                                            Month
                      2
                                                                            Used Marijuana on 300 or
                      1                                                     More Days in the Past Year

                      0
                          2002   2003   2004   2005   2006   2007   2008   2009   2010   2011   2012
MARIJUANA AND TEENS IN 2016 - DANIELLE RAMO, PHD ASSISTANT PROFESSOR IN RESIDENCE - PARENTS ...
Marijuana Use Disorder, Past Year, by Age:
                                                 2002-2014 NSDUH

                               Age 12 or older       Age 12 to 17   Age 18 to 25
                           7

                           6
Marijuana Use Disorder %

                           5

                           4

                           3

                           2
                                                                                        4.2 million
                           1

                           0

                                                                                   SAMHSA, 2015
MARIJUANA AND TEENS IN 2016 - DANIELLE RAMO, PHD ASSISTANT PROFESSOR IN RESIDENCE - PARENTS ...
Budney et al., 2007. ASCP
MARIJUANA AND TEENS IN 2016 - DANIELLE RAMO, PHD ASSISTANT PROFESSOR IN RESIDENCE - PARENTS ...
Medical Use of Cannabis
• CondiAons for which marijuana can aid in treatment
  – Pediatric Developmental and Behavioral Disorders
  – Cancer
  – Neurological CondiAons
     • Epilepsy
     • Headache
     • MulAple Sclerosis
  – DigesAve Disorders
     • Chemotherapy induced nausea
     • AppeAte sAmulant
     • Chronic inflammatory bowel disease
                                           Zhang & Ho; J. Addic; 2015
MARIJUANA AND TEENS IN 2016 - DANIELLE RAMO, PHD ASSISTANT PROFESSOR IN RESIDENCE - PARENTS ...
Marijuana Use in the Past Year among
    Individuals Aged 12 or Older:
     2002-2014 Na6onal Survey on Drug Use and Health, by State
MARIJUANA AND TEENS IN 2016 - DANIELLE RAMO, PHD ASSISTANT PROFESSOR IN RESIDENCE - PARENTS ...
Bay Area vs. California
               Adolescent Marijuana Use
                   2013-2014 California Healthy Kids Survey

• Used marijuana one or more Ames in the past year:
   • 9th grade:     30% Bay Area vs 26% California
   • 11th grade:    60% Bay Area vs 45% California

• Heavy use in the past month:
   • 9th grade:     11% Bay Area vs 8% California
   • 11th grade:    27% Bay Area vs 14% California

• 84% of 11th graders say it is fairly or very easy to get

• 73% of 9th graders say it is fairly or very easy to get.
Marijuana Delta-9 THC Levels
14%                                                          12.30%

12%

10%

8%                                      4.87%

6%                3.35%

4%
       0.74%
2%

0%
      1975        1990                  2000                   2012

                         NaAonal Center for Natural Products Research, 2012
How Marijuana is Used: Edibles
SubstanTal discrepancy between labels and actual
          THC content at dispensaries

              • 75 edible cannabis products tested
                (baked goods, beverages, candy/
                chocolate)
              • San Francisco, Los Angeles, SeaYle
              • THC content:
                 – 17% accurately labeled
                 – 23% underlabeled
                 – 60% overlabeled

              • Edible cannabis products fail to meet
                basic label accuracy standards for
                pharmaceuAcals.       Vandrey et al.; JAMA; 2015
Dabbing: Oil, Shatter, Wax

                                                    SACRAMENTO, Calif. (KCRA) —
                                                    “A growing number of
                                                    teenagers are smoking a highly
                                                    potent form of marijuana –
                                                    virtually undetected – with no
                                                    smell and no way for anyone to
                                                    know they’re breaking the
“It’s not for beginners” – Head of Business         law.”
Strategy and Development, Medicine Man                                  Feb 13, 2014
Dispensary, CO
                                         Feb 2014
Dabbing
• THC concentraAons of 20–
  25%, up to 80% vs.
  TradiAonal marijuana: 10%.
• Shared and normalized
  through social media (e.g.,
  YouTube)
• Considerable residual
  solvent and pesAcide
  contaminaAon (80%)

   Mehmedic et al. 2010; Krauss et al. 2015; Raber et al. 2015
Vaping marijuana

    Vaping
ELECTRONIC NICOTINE DELIVERY DEVICES
hYps://www.yahoo.com/tech/bluetooth-e-cigareYe-lets-you-receive-calls-and-listen-77079339081.html
Vaping
• Good epi data not available.

• TheoreAcal benefits:
   – May reduce negaAve health effects associated with
     inhalaAon of cannabis smoke
   – LimiAng the exposure of others to cannabis smoke.
   – Non-health benefits (e.g., discreet, increased delivery
     efficiency)

• Downside…
   – May lead to earlier iniAaAon of use, increased frequency
     or quanAty of use and decreased moAvaAon to quit or
     reduce use.
   – Promotes high concentrated, potenAally contaminated
     (and unregulated) forms of THC.
TesTmonial
Smartphone
                     Apps
• Content analysis of 59 cannabis-related mobile
  apps for Apple and Android devices
• Classified apps by feature and 20 content areas
• Most common content areas:
  – strain classificaAon (33.9%)
  – facts (20.3%)
  – games (20.3%)
• Only one app provided informaAon related to
  abuse, addicAon, or treatment
                                  Ramo et al.; JMIR mHealth uHealth; 2015
Health Consequences:
          Concerns for Teens

•   Risk of addicAon
•   Risk for other drug use
•   RelaAon to mental illness
•   Effects on school performance:
•   Short-term effects: Motor vehicle accidents,
    sexual risk behaviors

                                     Volkow et al. NEJM; 2014
Impact of Marijuana on Teen Users
Auer 7-30 days of absAnence in healthy
samples without independent mental
health problems…

• CogniAve impairments: Decreased
  story memory, poorer processing
  speed, execuAve funcAoning and
  complex aYenAon

• Structural abnormaliAes: PFC,
  cerebellum, amygdala, leu
  hippocampus

• AbnormaliAes in white maYer
  integrity

                                         Lisdahl et al 2013, 2014
Adolescent Onset Marijuana Use is Linked to
              Decline in Adult IQ

• 1,037 followed people from birth (1972-73) to age 38.
• MJ use measured at age 18, 21, 26, 32, & 38.
• Neuropsychological tesAng was conducted at age 13, before
  iniAaAon of MJ use, and again at age 38.
• Persistent MJ use was associated with neuropsychological
  decline FOR ADOLESCENT ONSET USERS (dx at 3 Amepoints ->
  8 IQ points lower at age 38).
• IQ decline persisted auer stopping use, but only for
  adolescent-onset users.

                                        Meier et al. Proc Natl Acad Sci; 2012
Current Legal Landscape
 WA                                 ND
                     MT
                                               MN
                                                                                                            ME
           ID                       SD                    WI                                      VT
OR                                                                   MI
                          WY                                                                NY        NH

                                                    IA                                                      MA
                                    NE                                                            CT
                                                                               OH     PA               RI
                                                          IL    IN                               NJ
      NV        UT             CO
                                         KS         MO                          WV           DE
                                                                                             MD
                                                                     KY              VA
                                                                                             DC
 CA
                                          OK                   TN
                                                     AR                              NC
                AZ             NM                                              SC

                                                          MS   AL         GA
                                         TX
                                                     LA

                                                                               FL

      AK

                               HI

                                                                          Marijuana Legal
                                                                          Medical Marijuana Legal

                                                                          Marijuana Possession Decriminalized
LegalizaTon and teen MJ use: Colorado
       2013-2014 NaTonal Survey on Drug Use and Health

                                              20
A]er legalizaTon in                           18
Colorado, past month                          16
MJ use:                                       14

                                % Age 12-17
• Increased by 20% in                         12
  Colorado                                    10         NaAonal
                                                         Average
• Declined 4% naAonally                       8
                                              6          Colorado
• Colorado youth ranked #1 in                            Average
  the naAon, up from #4                       4
                                              2
• In Colorado was 74% higher
                                              0
  than the naAonal average
  compared to 39%.
                                                    SAMHSA, 2015
2016 IniTaTves
  Control, Regulate and Tax Adult Use   Marijuana LegalizaTon IniTaTve
  of Marijuana Act (AUMA)               Statute (ReformCA)

  • Backed by Sean Parker, Lt.          • CoaliAon for Cannabis Policy
    Governor Gavin Newsom,                Reform
    Drug Policy Alliance,               • Grants authority to the
    Marijuana Policy Project              California Cannabis
  • Grants local authority to             Commission
    local and state governments

BOTH INITIATIVES ALLOW…..
• Industry representaAon in decision-making
• MarkeAng to under age 21
Concerns About Retail
          Cannabis Use
• NormalizaTon of marijuana use
  – In 2013, 19% of HS seniors reported they would
    try if legal for general use.
• Unanswered quesTons about effects of
  secondhand marijuana smoke exposure
• MarkeTng will reach youth
  – Products appealing to youth
  – AdverAsements in youth-consumed media (online).
  – “CigareYe people maintain peer pressure is the culprit in geyng
    kids to start smoking and that adverAsing has liYle effect. That’s
    like saying cosmeAc ads have no effect on girls too young to put
    on lipsAck.” (Commentator in Adver6sing Age trade journal)
• Limited regulaTons on dosing (esp. edibles)
Summary
• Marijuana is used frequently, especially by
  youth and young adults, and can cause short
  and long term health effects
• Lidle is known about the effects of legalizaTon
  on youth use and associated consequences.
• Yet, despite the lack of what is known:
  – Legal landscape is changing rapidly, incl. in CA
  – MarkeAng (incl. to youth) is going full steam ahead
  – In the absence of regulaAon, parents play an
    important role in sending messages about MJ use to
    teens
What Parents Can Do
• What you model is criAcally important
• Establish open communicaAon
  – Ask open-ended quesAons
  – Listen, listen and listen! Use the 3 to 1 rule
  – Control your emoAons
• Show you care (1:1 Ame)
• Set limits (It’s no too late!)
• Show acceptance and respect independence/
  privacy
How to Talk to Teens
              About Marijuana
• Have conversaAons, not lectures
  – Use ballot iniAaAve(s) or this talk as lead-in
  – Ask open-ended quesAons
• Share facts/ask quesAons about marijuana
  that counteract “harmless” noAon.
  – Affects the teen brain
  – Involved in accidents/deaths, especially for teens
  – New laws will create an industry focused on $$
• Share reasons NOT to smoke/vape
• Discuss how MJ is portrayed in the media
• Discuss how to handle peer pressure
More informaTon

• NIDA for Teens
  – hYps://teens.drugabuse.gov
• NIDA info on Marijuana
  – hYp://www.drugabuse.gov/drugs-abuse/marijuana
• CA Blue Ribbon Commission on MJ Policy
  – hYps://www.safeandsmartpolicy.org
• California Society for AddicAon Medicine: Youth
  First IniAaAve
  – hYp://www.csam-asam.org/sites/default/files/
    csam_youth_first_final_14.pdf
Common Scenarios
• “Have you ever smoked marijuana?”
• “How old were you when you first tried marijuana?”

• You overhear your child and a friend talking about an e-cigareYe device
  that “you can use with marijuana and no one can smell it.”

• Your child says that you should vote to legalize marijuana use in CA
  because the drug war is racist and unethical.

• Your son or daughter comes home from a party clearly high.

• Your son or daughter has turned 18 and wants to get a medical
  marijuana card.

• You’ve seen recent changes in mood/friends/school performance and
  you’re worried your son/daughter is using too much marijuana.
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