Neuro GASTRo 2017 24 - 26 August 2017 - University College Cork (UCC), Cork, Ireland - ESNM
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ESNM 2017
www.neurogastro2017.org
© Peter O'Toole / Shutterstock.com
Neuro
GASTRo 2017
Biennial Meeting of the European Society
of Neurogastroenterology and Motility
24 – 26 August 2017
University College Cork (UCC), Cork, Ireland
FINAL PRoGRAMME
01
Congress Venue University College Cork College Road Cork T12 YN60, Ireland Main Entrance on the corner of Western Road and Donovan Road www.ucc.ie Host Organisation ESNM – European Society of Neurogastroenterology & Motility c/o Vienna Medical Academy Alser Strasse 4 1090 Vienna, Austria Phone: +43 (0)1 405138331 Fax: +43 (0)1 4078274 Email: info@esnm.eu www.esnm.eu Congress and Exhibition Office CPO HANSER SERVICE Paulsborner Str. 44 14193 Berlin, Germany Phone: +49 (0)30 3006690 Fax: +49 (0)30 3057391 Email: neurogastro2017@cpo-hanser.de www.cpo-hanser.de
ESNM 2017
Table of Contents
04 Welcome Address 32 Overview of Meeting Rooms
05 Committees and Organiser 33 Congress Information
06 Structure of the Scientific Programme 35 General Information
07 Scientific Information – Overview 38 Acknowledgements / List of Exhibitors
Scientific Programme by Day 39 Exhibition Plan
10 Thursday, 24 August 2017
12 Friday, 25 August 2017 40 Industry Sponsored Sessions
15 Saturday, 26 August 2017
41 List of Chairpersons and Presenters
Poster Presentations / Tours by Day
18 Friday, 25 August 2017
25 Saturday, 26 August 2017
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03
ESNM 2017
Welcome Address
Welcome to Cork at NeuroGASTRO 2017, the Meeting of the European
Society of Neurogastroenterology and Motility (ESNM) in collaboration
with the APC Microbiome Institute and University College Cork.
We are excited to spend the next days with you to present, share and
debate on the latest basic and clinical science and research in the field
of Neurogastroenterology and Motility.
This is a unique opportunity to present your work, discuss your neu-
rogastroenterology research and clinical practice with numerous col- Giovanni Barbara Paul Enck
leagues and a distinguished faculty from Europe and around the globe.
NeuroGASTRO is a well-established European event that brings together
leading experts and emerging young investigators actively involved in
neurogastroenterology, digestive motility and functional gastrointes-
tinal diseases from Europe and from all around the world to discuss
cutting-edge research. The APC Microbiome Institute is recognised as
one of the leaders in the field of microbiome science.
Cork is the international gateway to Ireland’s Wild Atlantic Way with
Cork International Airport serving over 50 international destinations.
Cork is the Food Capital of Ireland, home to the birthplace of modern Niall Hyland Gerard Clarke
Irish Cuisine at Ballymaloe, the famed English Market and also home
to the best artisan food producers in the country. Don’t just take our
word for it – as Lonely Planet themselves said ‘Everything good about
Ireland can be found in County Cork’.
We hope to see you in Cork in 2017.
Giovanni Barbara Paul Enck Niall Hyland Gerard Clarke
ESNM ESNM ESNM Scientific University College
President Treasurer Committe Member Cork, Ireland
04
ESNM 2017
Committees & Organiser
Steering Committee Scientific Programme Committee
President Chairs
Giovanni Barbara, Italy Niall Hyland, Ireland
Gerard Clarke, Ireland
Treasurer
Members
Paul Enck, Germany
Roberto De Giorgio, Italy
David Grundy, United Kingdom
Councillors
Asbjørn Mohr Drewes, Denmark
Fernando Azpiroz, Spain
Sabine Roman, France
Serhat Bor, Turkey
Michael Schemann, Germany
Ram Dickman, Israel
André Smout, The Netherlands
Vasile Drug, Romania
Adam Farmer, United Kingdom
Niall Hyland, Ireland ESNM
Asbjørn Mohr Drewes, Denmark European Society of
Beate Niesler, Germany Neurogastroenterology & Motility
Luis Novais, Portugal c/o Vienna Medical Academy
Daniel Pohl, Switzerland Alser Strasse 4
Sabine Roman, France 1090 Vienna, Austria
Edoardo Savarino, Italy Phone: +43 (0)1 405138331
Jordi Serra, Spain Fax: +43 (0)1 4078274
André Smout, The Netherlands Email: info@esnm.eu
Jan Tack, Belgium www.esnm.eu
Alexander Trukhmanov, Russia
affiliated with
ESNM Awards
A limited number of travel awards are provided to investigators (35 years or
younger) who had an abstract accepted for presentation (oral or poster) based
on scientific quality of submission. The travel award includes a travel grant of
EUR 500 plus a free registration to the NeuroGASTRO congress. Payments will
be made in Euro after the congress. Please note that the presenting authors must
register and attend the meeting to be eligible for the award. All awards will be
delivered during the Closing Ceremony.
05ESNM 2017
Structure of the Scientific Programme
The scientific programme is structured according to days, Posters
time and room. All presenters are listed by name and the Authors are invited to present their latest research findings
title of their presentation. or important ongoing research as posters; these have been
grouped into areas of research by the NeuroGASTRO sci-
entific committee.
Plenary Lectures
The sessions will usually last 60 minutes. They focus on a
particular topic and present the very latest data related to it. TANDEM Session
The plenary lecture will include an expert speaker who will The ESNM and TANDEM are presenting the Young Investi-
first present their research followed by a closing discussion. gator Award supported by Nature Reviews Gastroenterology
Hepatology. The award includes a free registration to the
congress as well as a monetary grant of EUR 400 each for
Symposia the two winning teams of the TANDEM project.
These sessions will usually last 90 minutes. Each sympo-
sium will be chaired by two experts and will include three
speakers who first present their latest research data on a Industry Sponsored Session
particular topic followed by a wrap-up discussion. The Industry sponsored session is organised by the industry
in consultation with the scientific committee. The session
is scheduled for Friday during the congress but outside of
Free Presentations the scientific programme.
Selected abstract submissions will be presented during free
presentations generally lasting 60 minutes. Oral presenters
will be allocated 15 minutes for their presentation including
time for questions from the audience.
CME Accreditation
The NeuroGASTRO 2017 Congress in Cork, Ireland, 24 – 26 August 2017 was granted 16 European CME credits
(ECMEC) by the European Accreditation Council for Continuing Medical Education (EACCME).
06ESNM 2017
Scientific Information – Overview
Thursday, 24 August 2017
Room a Boole 4 Boole 3 Boole 1 Devere Devere Hall Boole 5
Time d Hall /Bearra
08:00
08:30
PGC-01 – Part 1
The Gut microbi-
09:00 ome and diet in
neurogastroenterol-
ogy: A guide for the
09:30 clinician
10:00
10:30
Coffee Break in Devere Hall
11:00 PGC-01 – Part 2
The Gut microbi-
07:30 – 18:30
11:30 ome and diet in
neurogastroenterol- ESNM General
ogy: A guide for the Assembly
12:00 clinician
– members only –
12:30 12:30 – 13:25
Opening of the
congress and life-
registratioin
13:00 time achievement
award
10:30 – 19:00
13:30
S-01 S-02 S-03
Dietary interven- Challenges in Neurogastroenter-
14:00 tions including pro- severe digestive ology: Across the
biotics, prebiotics disorders lifespan
and synbiotics
14:30
exhibition
15:00
Coffee Break in Devere Hall
15:30
FP-01 FP-02 FP-03
Dietary interven- Challenges in Neurogastroenter-
16:00 tions including pro- severe digestive ology: Across the
biotics, prebiotics disorders lifespan
and synbiotics
16:30
PL-01
17:00 The microbiome as
a regulator of the
17:30 brain-gut axis: ...
18:00
18:30 Welcome Reception
in the exhibition area Devere Hall
19:00
07ESNM 2017
Scientific Programme – Overview
Friday, 25 August 2017
Room a Boole 4 Boole 3 Boole 1 Devere Boole 5 Aula
Time d Hall Maxima
08:00
SS-01
GENIEUR-reloaded
08:30
09:00
S-04 S-05 S-06
Enteric plasticity Food allergies, Treatment of visceral
09:30 intolerances and pain – lessons from
FODMAPS pancreatitis
10:00
10:30
p-01 – p-09 poster tours 12:00 – 13:00
Coffee Break in Devere Hall
09:00 – 17:00
11:00 FP-04 FP-05 FP-06
07:00 – 18:30
Enteric plasticity Mixed topic from Treatment
11:30 paper session I of visceral pain
12:00
S-07 12:05 – 13:30
09:00 – 19:00
poster exhibition
Hot topics from the
12:30 Rome Foundation
research agenda Lunch in Devere Hall
registration
13:00
13:30
SA-01
exhibition
Industry sponsored
14:00 Symposium
14:30
PL-02 14:30 – 15:25
Translational perspec-
15:00 tives in Neurogastro-
enterology
15:30
S-10 S-08 S-09
Satellite Symposium New technologies in Stress and functional
16:00 NEUROGUT clinical neurogastro- gastrointestinal
enterology disorders
16:30
17:00
Coffee Break in Devere Hall
17:30 FP-07 FP-08
New technologies in Stress and functional
18:00 clinical neurogastro- gastrointestinal
enterology disorders
18:30
19:00
08ESNM 2017
Scientific Programme – Overview
Saturday, 26 August 2017
Room a Boole 4 Boole 3 Boole 1 Devere Boole 5 Aula
Time d Hall Maxima
08:00
08:30
09:00
FP-11 S-11 S-12
Mixed topic from Enterochromaffin cells, Biomarkers in irritable
09:30 paper session III endocrine cells and bowel syndrome
brush border cells:
Role in signalling from
p-10 – p-18 poster tours 12:00 – 13:00
poster exhibition 09:00 – 15:30
10:00 the lumen
08:00 – 16:30
10:30
Coffee Break in Devere Hall
09:00 – 16:00
11:00 IGM-01 FP-09 FP-10
Tandem Meeting Enterochromaffin cells, Biomarkers in irritable
11:30 endocrine cells and bowel syndrome
brush border cells:...
registration
12:00
exhibition
12:30
13:00
Lunch in Devere Hall
13:30
14:00
14:30
PL-03
Vagal neurocircuits in
15:00 neurogastroenterology
15:30 Closing Ceremony
and presentation of
16:00 best abstract awards
16:30
Abbreviations Scientific Overview
FP Free Presentations PL Plenary Lecture
IGM Tandem Meeting S Symposium
P Posters SA Industry Sponsored Session
PGC Post Graduate Course SS Special Session
09ESNM 2017
Scientific Programme by Day
Thursday, 24 August 2017
PGC-01 Postgraduate Course 004 Fecal microbial transplantation. Current and
future indications
08:30 – 08:40 Boole Lecture Theatre 1 Gianluca Ianiro, Italy
The Gut microbiome and diet in neurogastroenterology
– a guide for the clinician
Chairs: Eamonn Quigley, USA
Magnus Simrén, Sweden Opening Ceremony
001 Welcome and opening comments 12:30 – 13:25 Boole Lecture Theatre 4
Eamonn Quigley, USA Opening of the congress
Giovanni Barbara, Italy Chairs: Paul Enck, Germany
Giovanni Barbara, Italy
08:40 – 09:30 Niall Hyland, Ireland
Characterising the Gut microbiome in clinical practice
12:30 – 12:45
001 Techniques used to characterize the gut micro- Welcome address
biota: A guide for the clinician
Paul Cotter, Ireland 12:45 – 12:55
Presentation of the lifetime achievement award
002 Influence of diet and exercise on the gut micro-
biome 12:55 – 13:25
Orla O‘Sullivan, Ireland Opening Lecture
Developments in clinical neurogastroenterology
09:30 – 10:30 André Smout, The Netherlands
Microbiome profiling as a diagnostic or prognostic bio-
marker of disease
001 Challenges in using gut microbiota analysis as
S-01 Symposium
a diagnostic/prognostic tool in diseases and dis-
orders 13:30 – 15:00 Boole Lecture Theatre 4
Marcus Claesson, Ireland Dietary interventions including probiotics, prebiotics
and synbiotics
002 Microbiota signatures and gastrointestinal symp-
Chairs: Siobhain O´Mahony, Ireland
toms
Fernando Azpiroz, Spain
Magnus Simrén, Sweden
003 The gut microbiome and IBS: The GENIEUR 001 Probiotic effects on gut physiology
approach to clinical phenotyping Vassilia Théodorou, France
Mirjana Rajilic-Stojanovic, Serbia 002 Pharmabiotic manipulation of the microbiota in
gastrointestinal disorders: A clinical perspective
Eamonn Quigley, USA
003 Early life nutritional bioactives in neurogastro-
10:30 – 11:00 Coffee Break in Devere Hall enterology
Sharon Donovan, USA
11:00 – 12:20
Considerations in choosing microbiome targeted therapies
S-02 Symposium
001 Microbiome-gut-brain axis; clinical implications
13:30 – 15:00 Boole Lecture Theatre 3
for neurogastroenterology
Timothy Dinan, Ireland Challenges in severe digestive disorders
Chairs: Jan Tack, Belgium
002 Dietary interventions for functional bowel symp- Nathalie Rommel, Belgium
toms; impact and relevance of diet-microbiome
interactions 001 Oesophageal achalasia
Hans Törnblom, Sweden Guy Boeckxstaens, Belgium
003 Prebiotics, probiotics and synbiotics in neuro- 002 Gastroparesis
gastroenterology – what are the outcomes? Vincenzo Stanghellini, Italy
Alex Ford, United Kingdom
003 Severe intestinal dysfunctions
Roberto De Giorgio, Italy
10ESNM 2017
Scientific Programme by Day
Thursday, 24 August 2017
S-03 Symposium 002 Delivery of neural stem cells to the gut using
mesenterial perfusion
13:30 – 15:00 Boole Lecture Theatre 1 Lisa Marx, Germany
Neurogastroenterology: Across the lifespan
003 Effects of intestinal alkaline phosphatase on in-
Chairs: Michel Neunlist, France
testinal permeability and bacterial translocation
Agata Mulak, Poland
in an experimental model for sepsis
001 The Gut microbiota and healthy aging Philip Plaeke, Belgium
Paul O‘Toole, Ireland 004 Inflammatory state and phenotypic switch of
002 Ageing and neurogastroenterology human smooth muscle in diverticulosis and
Gareth Sanger, United Kingdom complicated diverticular disease
Carola Severi, Italy
003 Paediatric neurogastroenterology: A clinical
perspective
Nikhil Thapar, United Kingdom
FP-03 Free Presentation
15:30 – 16:30 Boole Lecture Theatre 1
Neurogastroenterology: Across the lifespan
15:00 – 15:30 Coffee Break in Devere Hall Chairs: Gareth Sanger, United Kingdom
Nikhil Thapar, United Kingdom
001 Brain-microbiome-behavior associations follow-
FP-01 Free Presentation ing early adversity: A proof of concept study
across development
15:30 – 16:30 Boole Lecture Theatre 4 Bridget Callaghan, USA
Dietary interventions including probiotics, prebiotics
002 Development of coordinated electrical activity
and synbiotics
in the human foetal enteric nervous system
Chairs: Vassilia Théodorou, France
Conor McCann, United Kingdom
Sharon Donovan, USA
003 Infant faecal microbiome diversity and behav-
001 Bifidobacterium Breve NCFB 2258 stimulates ioural outcomes at age two
vagal nerve firing across an intact colonic barrier Amy Loughman, Australia
Dervla O‘Malley, Ireland
004 Development of functional innervation of the
002 Protease activity and tryptase expression is in- gastrointestinal mucosa
creased in a post-inflammatory rat model for Marlene Hao, Australia
visceral hypersensitivity
Hannah Ceuleers, Belgium
003 Influence of the herbal extract combination STW
5 on the human intestinal microbiota in vitro PL-01 Plenary Lecture
Heba Abdel-Aziz, Germany 16:45 – 17:45 Boole Lecture Theatre 4
004 Disruption of colonic microbiome and circulating The microbiome as a regulator of the brain-gut axis:
metabolome in antibiotic-treated mice From stress to visceral pain
Angela Jacan, Austria Chair: Timothy Dinan, Ireland
001 The microbiome as a regulator of the brain-gut
axis: From stress to visceral pain
FP-02 Free Presentation John F. Cryan, Ireland
15:30 – 16:30 Boole Lecture Theatre 3
Challenges in severe digestive disorders
Chairs: Guy Boeckxstaens, Belgium Welcome Reception
Roberto De Giorgio, Italy
18:00 – 19:00 Devere Hall
001 Novel mutations in neurogenic chronic intestinal
pseudo-obstruction identified by high-through-
put sequencing
Francesca Bianco, Italy
11ESNM 2017
Scientific Programme by Day
Friday, 25 August 2017
SS-01 SPECIAL SESSION S-06 Symposium
08:00 – 09:00 Boole Lecture Theatre 1 09:00 – 10:30 Boole Lecture Theatre 1
GENIEUR-reloaded Treatment of visceral pain – lessons from pancreatitis
Chairs: Beate Niesler, Germany Chairs: André Smout, The Netherlands
Magnus Simrén, Sweden Adam Farmer, United Kingdom
001 Up-date GENIEUR activities 001 Basic mechanisms
Beate Niesler, Germany; Magnus Simrén, Sweden Ihsan Ekin Demir, Germany
002 LINK award project ‘HELP EU in IBS’ 002 Translational aspects – central sensitization
Beate Niesler, Germany; Magnus Simrén, Sweden Søren Schou Olesen, Denmark
Lobbying for IBS research 003 Algorithm based personalized treatment
Beate Niesler, Germany; Magnus Simrén, Sweden Asbjørn M. Drewes, Denmark
003 AOB
Beate Niesler, Germany; Magnus Simrén, Sweden
10:30 – 11:00 Coffee Break in Devere Hall
S-04 Symposium
09:00 – 10:30 Boole Lecture Theatre 4
Enteric plasticity FP-04 Free Presentation
Chairs: Nick Spencer, Australia 11:00 – 12:00 Boole Lecture Theatre 4
Kirsteen Browning, USA
Enteric plasticity
001 Enteric neurotransmission Chairs: Michael Schemann, Germany
Michael Schemann, Germany Andreas Friebe, Germany
002 Central nervous system diseases and the gas- 001 Role of semaphorin 3A in the postnatal devel-
trointestinal tract opment of the enteric nervous system
Michel Neunlist, France Jacques Gonzales, France
003 Interstitial cells of cajal 002 Small intestine neuromuscular dysfunctions in
Andreas Friebe, Germany Toll-like receptor 4-null mice: Role of enteric glia
Silvia Cerantola, Italy
003 ANO1 knockdown causes disrupted antral pace-
maker activity, discordinated popagating antral
S-05 Symposium
contractions and delayed gastric emptying
09:00 – 10:30 Boole Lecture Theatre 3 Sean Ward, USA
Food allergies, intolerances and FODMAPS 004 Single cell photo-stimulation elicits neuron-
Chairs: Hans Törnblom, Sweden to-glia communication in the enteric nervous
Magnus Simrén, Sweden system
Werend Boesmans, Belgium
001 Food allergies and eosinophilic esophagitis
Sabine Roman, France
002 Role of FODMAPS
Jessica Biesiekierski, Belgium
003 Gluten and wheat sensitivity
Umberto Volta, Italy
12ESNM 2017
Scientific Programme by Day
Friday, 25 August 2017
FP-05 Free Presentation
11:00 – 12:00 Boole Lecture Theatre 3
12:00 – 14:30 Lunch Break in Devere Hall
Mixed topic free paper session I
Poster Tours in Aula Maxima
Chairs: Jessica Biesiekierski, Belgium
Umberto Volta, Italy
001 Proton pump inhibitor therapy improves esoph- S-07 Symposium
ageal symptoms by restoring a normal esoph- 12:05 – 13:30 Boole Lecture Theatre 4
ageal peristalsis in patients with proton pump
inhibitor-response esophageal eosinophilia Hot topics from the Rome Foundation research agenda
Marco della Coletta, Italy Chairs: Jan Tack, Belgium
Giovanni Barbara, Italy
002 Actions of bis-(p-hydroxyphenyl)-pyridyl-2-
methane – the active metabolite of the laxative 001 The Rome Foundation: Programs and activities
bisacodyl – on human intestine in vitro Jan Tack, Belgium
Dagmar Krueger, Germany 002 Global epidemiological study of the FGIDs
003 Low-dose penicillin exposure in adolescent mice Ami D. Sperber, Israel
has long-term, sex-dependent consequences on 003 Brain imaging and FGID
behaviour and physiology Lukas van Oudenhove, Belgium
Karen-Anne McVey Neufeld, Canada
004 Rome IV: New diagnostic criteria for functional
004 Corticotropin-releasing factor in activated esophageal disorders
mucosal eosinophils is associated with clini- Qasim Aziz, United Kingdom
cal severity in diarrhea-prone Irritable Bowel
Syndrome (IBS)
Eloisa Salvo Romero, Spain
SA-01 Industry sponsored session
13:30 – 14:30 Boole Lecture Theatre 3
FP-06 Free Presentation see page 40
11:00 – 12:00 Boole Lecture Theatre 1
Treatment of visceral pain
Chairs: Asbjørn M. Drewes, Denmark PL-02 Plenary Lecture
Ihsan Ekin Demir, Germany
14:30 – 15:25 Boole Lecture Theatre 4
001 Faecal supernatants from diarrhoea predominant Translational perspectives in neurogastroenterology
Irritable Bowel Syndrome (IBS) patients disrupt Chair: Eamonn Quigley, USA
colonic epithelial barrier function and directly
activate colo-rectal afferent nerves 001 Translational perspectives in neurogastroen-
Hannah Wardill, Australia terology
Jan Tack, Belgium
002 Abdominal pain in hypermobile Ehlers Danlos
Syndrome (hEDS) may be associated with pro-
liferation of colonic nociceptive nerve endings
Rubina Aktar, United Kingdom S-10 Symposium
003 The histamine receptor H4 is functionally ex- 15:30 – 17:00 Boole Lecture Theatre 4
pressed on murine colonic sensory neurons and Satellite Symposium NEUROGUT
contributes to chronic visceral hypersensitivity Chairs: Paul Enck, Germany
Annemie Deiteren, Australia Giovanni Barbara, Italy
004 Involvement of the serotonin pathway in ileal 001 The NEUROGUT Initial Training Network (ITN)
neuromotor dysfunction associated with TLR2 2014 – 2018 – Introduction
and TLR4 inhibition in juvenile mice Paul Enck, Germany
Ilaria Marsilio, Italy
002 NEUROGUT progress, as seen from a PI
David Grundy, United Kingdom
13ESNM 2017
Scientific Programme by Day
Friday, 25 August 2017
003 NEUROGUT Training, seen by a trainee FP-07 Free Presentation
Annikka Polster, Sweden
17:30 – 18:30 Boole Lecture Theatre 3
004 NEUROGUT Training Network, an external ad-
New technologies in clinical neurogastroenterology
visor´s perspective
Chairs: Carolina Malagelada, Spain
Jackie Wood, USA
Serhat Bor, Turkey
001 Optogenetic induction of propagating colonic
motor complexes and propulsion of fecal content
S-08 Symposium induced by light
15:30 – 17:00 Boole Lecture Theatre 3 Nick Spencer, Australia
New technologies in clinical neurogastroenterology 002 Assessment of Duodeno/Jejunal baseline im-
Chairs: Sabine Roman, France pedance as a surrogate of evaluation of mucosal
Martin Buckley, Ireland integrity in patients with functional dyspepsia:
Importance of timing of measurement relative
001 What is the future of impedance planimetry? to phase III of the MMC
Hans Gregersen, Hong Kong SAR, China Kenichiro Nakagawa, United Kingdom
002 Adjunction of impedance measurements to es- 003 A comparison of the efficacy and safety of two
ophageal manometry: Is it really better than dosing regimens, 2 and 5 times per week, of an
manometry alone? intraluminal vibrating capsule in the manage-
Nathalie Rommel, Belgium ment of chronic idiopathic constipation
003 Luminal imaging Eamonn Quigley, USA
Carolina Malagelada, Spain 004 MRI detection and histological localization of
transplanted neural crest derived stem cells
(NCSCs) labeled with superparamagnetic nan-
oparticles in future perspectives for cell therapy
S-09 Symposium of Hirschsprung‘s disease
15:30 – 17:00 Boole Lecture Theatre 1 Jasmin Clasohm, Germany
Stress and functional gastrointestinal disorders
Chairs: Niall Hyland, Ireland
Serhat Bor, Turkey
FP-08 Free Presentation
001 Genetics and epigenetics of the stress response 17:30 – 18:30 Boole Lecture Theatre 1
Rene van den Wijngaard, The Netherlands
Mixed topic free paper session II
002 Brain imaging and stress Chairs: Sigrid Elsenbruch, Germany
Sigrid Elsenbruch, Germany Rene van den Wijngaard, The Netherlands
003 Psychological therapies in functional bowel dis- 001 Satiety is modulated by the intraluminal colonic
orders volume in healthy subjects
Gabriele Moser, Austria Noemi Caballero de Garcia, Spain
002 Duodenal acidification impairs duodenal integ-
rity and activates the duodenogastric reflex,
independently from mast cell activation
17:00 – 17:30 Coffee Break in Devere Hall Tim Vanuytsel, Belgium
003 Dopamine transporter genetic reduction affects
small-bowel neuromuscular contractility in mice
Valentina Caputi, Italy
004 Altered expression of the homeobox transcrip-
tion factor Phox2b in the myenteric plexus of
patients with diverticular disease
François Cossais, Germany
14ESNM 2017
Scientific Programme by Day
Saturday, 26 August 2017
FP-11 Free Presentation S-12 Symposium
09:00 – 10:30 Boole Lecture Theatre 4 09:00 – 10:30 Boole Lecture Theatre 1
Mixed topic free paper sessions III Biomarkers in irritable bowel syndrome
Chairs: Luis Novais, Portugal Chairs: Gerard Clarke, Ireland
Goran Hauser, Croatia Niall Hyland, Ireland
001 Serum from patients with Crohn´s Disease ac- 001 GENIEUR: Genes in IBS
tivates guinea pig enteric neurons Beate Niesler, Germany
Maria Lazarou, Germany
002 Microbiome and IBS
002 Colorectal cancer cells induce neurogenesis in Mirjana Rajilic-Stojanovic, Serbia
the enteric nervous system of the tumor mi-
003 Clinical biomarkers in irritable bowel syndrome
croenvironment via a NGF-dependent pathway
Magnus Simrén, Sweden
Farouk Drissi, France
003 Neurodegeneration of the ENS might be pre-
vented by treatment with nanomodified anti-
oxidants
Karl-Herbert Schäfer, Germany 10:30 – 11:00 Coffee Break in Devere Hall
004 Electrophysiological changes and mucosal per-
meability in phenotypes of gastroesophageal
reflux disease
Pelin Ergun, Turkey IGM-01 TANDEM Meeting
11:00 – 12:00 Boole Lecture Theatre 4
TANDEM meeting
Chairs: Paul Enck, Germany
S-11 Symposium Miriam Goebel-Stengel, Germany
09:00 – 10:30 Boole Lecture Theatre 3
Enterochromaffin cells, endocrine cells and brush bor-
der cells: Role in signalling from the lumen
Chairs: Roberto De Giorgio, Italy FP-09 Free Presentation
Siobhain O´Mahony, Ireland
11:00 – 12:00 Boole Lecture Theatre 3
001 Luminal nutrient transport and signalling Enterochromaffin cells, endocrine cells and brush bor-
Inge Depoortere, Belgium der cells: Role in signalling from the lumen
Chairs: Fiona Gribble, United Kingdom
002 Gut-derived hormones and the brain-gut axis
Catia Sternini, USA
Fiona Gribble, United Kingdom
003 ECC cells as a site of taste for luminal bacteria 001 Intrauterine growth retardation in rats alters
Catia Sternini, USA palmitoleate sensing by duodenal entero-en-
docrine cells, leading to increased-intestinal
permeability
Marieme Ndjim, France
002 Long-term effects of Roux-en-Y gastric bypass
surgery on colonic nutrient-sensing receptors
and enteroendocrine cells
Madusha Peiris, United Kingdom
003 Multiple nutrient stimulation enhances enteroen-
docrine cell responses in human and mouse colon
Madusha Peiris, United Kingdom
004 L-cells are key to cross-barrier signalling to the
host peripheral nervous system by a GLP-1-se-
creting putative probiotic
Eilish Brosnan, Ireland
15ESNM 2017
Scientific Programme by Day
Saturday, 26 August 2017
FP-10 FREE PRESENTATIoN
11:00 – 12:00 Boole Lecture Theatre 1
Biomarkers in irritable bowel syndrome
Chairs: Mirjana Rajilic-Stojanovic, Serbia
Visit the Poster
Daniel Pohl, Switzerland
Exhibition
001 Granins are linked to bacterial richness, innate
immunity, markers for intestinal permeability in Aula Maxima
and symptom severity IBS patients
Johanna Sundin, Sweden
002 Insular brain metabolites are related to somatic on Friday, 25 August 2017
symptom burden and cognitive coping in Irrita- from 09:00 – 17:00 and
ble Bowel Syndrome (IBS)
Adriane Icenhour, Sweden
on Saturday, 26 August 2017
003 Magnetic resonance imaging assessed small
bowel dysmotility and its relationship with pa- from 09:00 – 15:30
tient reported symptoms: An exploration of au-
tomated vs subjective assessment techniques
Ruaridh Gollifer, United Kingdom
004 Lactobacillus rhamnosus GG soluble mediators
ameliorate visceral hypersensitivity and changes
in spinal cord gene expression induced by early
life stress
Karen-Anne McVey Neufeld, Canada
12:00 – 14:30 Lunch Break in Devere Hall
Poster Tours in Aula Maxima
PL-03 PLENARy LECTuRE
14:30 – 15:30 Boole Lecture Theatre 4
Vagal neurocircuits in neurogastroenterology
Chair: David Grundy, United Kingdom
001 Vagal neurocircuits in neurogastroenterology
Kirsteen Browning, USA
CLoSING CEREMoNy
15:30 – 16:30 Boole Lecture Theatre 4
Closing Ceremony and
presentation of best abstract awards
16FNM 2018
3rd Meeting of the Federation of Neurogastroenterology and
Motility and Postgraduate Course on Gastrointestinal Motility
29 August – 1 September 2018
RAI Convention Center
Amsterdam, the Netherlands SAVE TH
E
DATE
vichie81 @ – fotolia.com
Hosting Society Associated Partners
ESNM – European Society of ANGMA – Australasian Neurogastro-
Neurogastroenterology and Motility enterology and Motility Association
SLNG – Sociedad Latinoamericana
Co-organisers de Neurogastroenterología
ANMS – American Neurogastro-
enterology and Motility Society
Congress and Exhibition office
ANMA – Asian Neurogastro-
enterology and Motility
Association CPO HANSER SERVICE
Zum Ehrenhain 34
22885 Barsbüttel // Germany
Phone: +49 – 40 – 670 88 20
Fax: +49 – 40 – 670 32 83
Email: fnm2018@cpo-hanser.de
www.fnm2018.orgESNM 2017
Poster Presentations / Tours by Day
Friday, 25 August 2017
P-01 Poster Presentation 003 Functional compensation of gastro intestinal
motility indicates enteric plasticity in an early
12:00 – 13:00 Aula Maxima onset model of Alzheimer‘s Disease
Dietary interventions including probiotics, prebiotics Jasmin Clasohm, Germany
and synbiotics S. Ull-Sopha, N. Stoye, K. Endres, H. Rabe, K.-H.
Discussant: Schäfer
Sharon Donovan, USA Abstracts 001 – 005
004 nELAV mRNA-binding protein, HuC/D alteration
in adolescent mice small intestine after antibi-
001 Sheep and cow milk and yogurt drinks influence
otic treatment-induced dysbiosis
gastrointestinal transit in a rat model
Cristina Giaroni, Italy
Julie Dalziel, New Zealand
M. Bistoletti, V. Caputi, F. Fagiani, V. Filpa, I.
C. Berry, G. Smolenski, S. Haines, L. Day
Marsilio, S. Cerantola, F. Crema, A. Baj, A. Pas-
002 Obesity-induced alterations in colonic transit cale, M. C. Giron
are normalized by dietary prebiotic supplemen-
005 Glial PGE2 production induced by inflammation
tation: role of gut microbiota
regulates glial response to ATP
Anna Golubeva, Ireland
Malvyne Rolli-Derkinderen, France
D. Kandil, S. Arboleya, A. Burokas, K. Murphy, C.
T. Rousseau, E. Baudu, C. Pochard, M. Neunlist
Stanton, N. Hyland, G. Clarke, T. Dinan, H. Schell-
ekens, J. Cryan 006 Pitfalls in the interpretation of high-resolution
anorectal manometry
003 Diurnal regulation of colonic motility by short-
Eva Sandell, Sweden
chain fatty acids
E. Lindgren, L. Flodqvist, G. Lindberg
Anneleen Segers, Belgium
L. Desmet, T. Thijs, K. Verbeke, J. Tack, I. Depoortere
004 High fat diet-induced depression-like behaviour P-03 Poster Presentation
in mice: Roles of intestinal microbiome, neuro-
peptide Y, and brain metabolome 12:00 – 13:00 Aula Maxima
Ahmed M. Hassan, Austria Neurogastroenterology: Across the lifespan
G. Mancano, K. Kashofer, E. E. Fröhlich, A. Matak, Discussants:
R. Mayerhofer, F. Reichmann, M. Olivares, A. M. Gareth Sanger, United Kingdom Abstracts 001 – 005
Neyrinck, N. M. Delzenne, S. P. Claus, P. Holzer Agata Mulak, Poland Abstracts 006 – 011
Nikhil Thapar, United Kingdom Abstracts 012 – 016
005 Effects of different bacterial strains in the form of
the Probiotics Symbioflor® on the enteric nerv- 001 Motor function of digestive tract at children
ous system and gut motility with the obesity
Maximilian Weyland, Germany Ekaterina Aleshina, Russia
D. Grundmann, L. Marx, M. Martin, M. Hau, K.-H. A. Khavkin, V. Novikova, S. Shoferova, M. Komis-
Schäfer sarova, L. Vorontsova
002 Extracellular matrix composition in the enteric
P-02 Poster Presentation nervous system of mice
Cristiano Bacarin, Brazil
12:00 – 13:00 Aula Maxima
P. Da Silva Watanabe, A. Franciosi, J. D.L. Mendes,
Enteric plasticity R. Aktar, L. A. Blackshaw, E. J.A. Araujo
Discussant:
Michael Schemann, Germany Abstracts 001 - 006 003 Role of NO-GC on long distance contractions in
the murine colon
001 Expression and neurochemical identity of sen- Katharina Beck, Germany
sory fibres is altered in Inflammatory Bowel B. Voussen, A. Vincent, D. Groneberg, S. P. Parsons,
Disease (IBD) J. D. Huizinga, A. Friebe
Madusha Peiris, United Kingdom 004 Distribution of RAD21 immunoreactivity in
R. Kaur Kahlon, R. Aktar, S. Raynel, L. A. Blackshaw mouse and human gut neurons
002 Enteric glial cells reaction to inflammation is Francesca Bianco, Italy
lost in Crohn‘s Disease S. J. Gibbons, E. Bonora, S. T. Eisenman, P. Claven-
Malvyne Rolli-Derkinderen, France zani, R. De Giorgio, G. Farrugia
C. Pochard, T. Clairembault, N. Cenac, E. Duchalais,
A. B. Bourreille, M. Neunlist
18ESNM 2017
Poster Presentations / Tours by Day
Friday, 25 August 2017
005 Patients with all types of congenital anorectal 014 Responsibility of patients towards the manage-
malformation seem to have fecal continence ment of their Irritable Bowel Syndrome (IBS):
reflexes A qualitative study
Jara Jonker, The Netherlands Tudor-Stefan Rotaru, Romania
V. den Hollander, M. Trzpis, P. Broens V.-L. Drug
006 Degree of colonic cholinergic innervation de- 015 Trivalent chromium suppresses gastrointestinal
termines bacterial translocation in pediatric motility and secretion in experimentally altered
Morbus Hirschsprung patients gut homeostasis in laboratory rodents
Simone Keck, Switzerland Olugbenga Odukanmi, Nigeria
S. Holland-Cunz A. Salami, K. Ogunwole, O. Busari, T. Homma, S.
Olaleye
007 Neuromuscular changes in asymptomatic diver-
ticulosis and diverticular disease 016 Innovative technology solutions to explore ef-
Christina Lange, Germany fects of the microbiome on intestine and brain
M. Barrenschee, F. Cossais, I. Hohmeier, M. Ebsen, I. pathophysiology
Vogel, J.-H. Egberts, T. Becker, M. Böttner, T. Wedel Roisin Owens, France
008 The herbal medicine STW 5 is efficacious in
targeting dyspeptic symptoms in all ages:
P-04 Poster Presentation
A meta-analysis of randomized controlled trials
Olaf Kelber, Germany 12:00 – 13:00 Aula Maxima
J. Müller, B. R. Vinson, C. Fink, H. Abdel-Aziz, M. New technologies in clinical neurogastroenterology
Storr, K. Kraft, K. Nieber Discussants:
009 Investigation of the brain gut axis in the rAAV-al- Sabine Roman, France Abstracts 001 – 005
pha-synuclein PD model: Reveals enteric nerv- Martin Buckley, Ireland Abstracts 006 – 010
ous system pathology and alterations in the gut Hans Gregersen, China Abstracts 011 – 015
microbiome Nathalia Rommel, Belgium Abstracts 016 – 020
Sarah O‘Donovan, Ireland
E. K. Crowley, J. Browne, O. O‘Sullivan, O. O‘Leary, 001 Dynamic MRI for bowel motility imaging: How
S. Timmons, Y. M. Nolan, P. O‘Toole, D. J. Clarke, fast and how long?
N. Hyland, S. Joyce, A. M. Sullivan, C. O‘Neill C.S. de Jonge, The Netherlands
R. Gollifer, A. J. Nederveen, D. Atkinson, S. A. Tay-
010 Depressive symptoms during pregnancy disrupt lor, J. Stoker, A. Menys
gut microbiome dynamics during critical prena-
tal and postnatal time windows 002 Spectral bowel motility assessment using dy-
Katie Togher, Ireland namic tagged MRI
A. Khashan, L. Kenny, C. Stanton, I. Carafa, K. Mur- C.S. de Jonge, The Netherlands
phy, G. O‘Keeffe, A. Ryan, J. F. Cryan, T. Dinan, G. A. M. Sprengers, A. J. Nederveen, J. Stoker
Clarke 003 Volume vs. caloric stimulation of small bowel
011 Effects of nitric oxide on small intestinal motility motility in healthy controls
Barbara Voussen, Germany C.S. de Jonge, The Netherlands
K. Beck, N. Mauro, J. Keppler, D. Groneberg, A. Friebe A. Menys, K. L. van Rijn, A. J. Nederveen, J. Stoker
012 The cells and conductance mediating cholinergic 004 Ultrasound and wireless motility capsule find-
neurotransmission in the stomach ings in patients with Familial GUCY2C diarrhea
Tae-Sik Sung, USA syndrome
S.-J. Hwang, S.-D. Koh, Y. Bayguinov, P. Blair, J. Odd Helge Gilja, Norway
Rock, T. Webb, L. O‘Kane, K. Sanders, S. Ward H. von Volkmann, I. Brønstad, D. A. Sangnes, K.
Nylund, R. Tronstad, T. Hausken, G. Dimcevski, T.
013 The influence of calorie restriction on gut mi- Fiskerstrand
crobiota in long-living Ames dwarf mice
Denise Wiesenborn, Germany 005 Fecobionics: A novel integrated bionics test of
A. Schneider, B. Victoria, L. Spinel, D. Grundmann, anorectal function
E. Galvez, T. Strowig, M. Masternak, K.-H. Schäfer Hans Gregersen, Hong Kong SAR, China
006 Standardizing parameters of high resolution
duodenojejunal manometry in healthy controls
William Hasler, USA
J. Baker, J. Dickens, M. Koenigsknecht, A. Fioritto,
K. Shedden, G. Amidon, D. Sun
19ESNM 2017
Poster Presentations / Tours by Day
Friday, 25 August 2017
007 In vivo assessment of foods that stimulate in- 017 Digestive functional scintigraphy for digestive
testinal secretions using magnetic resonance autonomic neuropathy diagnosis: About a case
imaging: Implications for dietary advice in ile- Nesrine Robaine, France
ostomy care J. M. Senard, L. Sailler, I. Berry, G. Victor
Victoria Wilkinson-Smith, United Kingdom
018 Gastric emptying patterns in diabetic patients
G. Major, L. Ashleigh, K. Murray, C. Hoad, L. Mar-
with functional digestive symptoms: First results
ciani, P. Gowland, R. Spiller
in 45 patients
008 Gastrointestinal peptides during chronic gastric Nesrine Robaine, France
electrical stimulation in patients with intractable O. Lairez, P. Pascal, I. Berry, G. Victor
vomiting
019 Per oral endoscopic myotomy for the manage-
Mathieu Meleine, France
ment of pediatric achalasia
C. Melchior, P. Prinz, A. Penfornis, B. Coffin, A.
Tsili Zangen, Israel
Stengel, P. Ducrotte, G. Gourcerol
020 Higher baseline cardiac vagal tone implicates
009 Morpho-functional evaluation of the gut in cystic
a subcortical functional brain network during
fibrosis
acute oesophageal pain
Carolina Malagelada, Spain
James Ruffle, United Kingdom
A. Bendezu, X. Molero, D. Sihuay, A. Nieto, X. Me-
S. Coen, V. Giampietro, S. Williams, A. Farmer,
rino, A. Accarino, J.-R. Malagelada, F. Azpiroz
Q. Aziz
010 A case for developing a preventative swallow
health maintenance program in the elderly
P-05 Poster Presentation
Dilpesh Agrawal, USA
M. Kern, F. Edeani, P. Sanvanson, R. Shaker 12:00 – 13:00 Aula Maxima
011 Rehabilitation of a heterogeneous group of dys- Biomarkers in irritable bowel syndrome/ treatment of
phagic patients by a novel exercise technique visceral pain
of swallowing against laryngeal restriction Discussants:
Dilpesh Agrawal, USA Gerard Clarke, Ireland Abstracts 001 – 006
M. Kern, F. Edeani, P. Sanvanson, R. Shaker Magnus Simrén, Sweden Abstracts 007 – 013
012 The diagnostic value of esophageal mucosal and 001 Longitudinal analysis of IBS patients reveals
baseline impedance measurements in patients that acquired immune responses are inhibited
with gastroesophageal reflux disease in symptom flare vs. symptom free
Sezgi Kipcak, Turkey Patrick Hughes, Australia
P. Ergun, S. Bor C. Mavrangelos, M. Campaniello, J. Andrews, P.
013 Characterization of GERD patients using pres- Bampton
sure-flow analysis 002 A functional SNP of the serotonin transporter
Ans Pauwels, Belgium gene promoter is associated with IBS
C. Scheerens, T. Omari, J. Tack, N. Rommel Beate Niesler, Germany
014 Interobserver and intraobserver agreement S. Mohr, N. Hattensperger, C. Martinez, L. Houghton,
in classification of defaecatory disorders on S. Schmitteckert, M. Goebel-Stengel, M. Kabisch, C.
high-resolution anorectal manometry Hammer, D. Knab, I. Vulic, M. D‘Amato, T. Zheng,
Abhishek Sadalage, India H. Mönnikes, S. Berens, F. Kraus, V. Andresen, T.
A. Shukla, D. Agrawal, D. Gupta, P. Abraham, M. Frieling, J. Keller, C. Pehl, C. Thöringer, G. Clarke,
Meshram, S. Bhatia P. J. Kennedy, J. F. Cryan, T. G. Dinan, E. Quigley, R.
Spiller, C. Beltrán, W. Herzog, G. Sayuk, E. A. Mayer,
015 Post-reflux swallow-induced peristaltic wave M. Gazouli, L. Kapur-Pojskic, M. Bustamante, X.
index and mean nocturnal baseline impedance Estivill, K. Rabionet, G. Boeckxstaens, M. Wouters,
predict heartburn response to proton pump in- M. Simrén, G. A. Rappold, M. Vicario, R. Schäfert,
hibitors better than acid exposure time in GERD J. Lorenzo-Bermejo, J. Santos, B. Niesler
Edoardo Savarino, Italy
M. Frazzoni, N. de Bortoli, S. Tolone, V. Savarino, 003 Heart rate variability characteristics of patients
L. Frazzoni with Irritable Bowel Syndrome (IBS) and asso-
ciation with symptoms
016 The role of biofeedback therapy in functional Annikka Polster, Sweden
disorders P. Friberg, B. Le Nevé, H. Törnblom, M. Simren
Oksana Fomenko, Russia
A. Y. Titov, S. Belousova, D. Egorova
20ESNM 2017
Poster Presentations / Tours by Day
Friday, 25 August 2017
004 IBS subgroups based on combination of GI and 013 Identification of an analgesic lipopeptide pro-
non-GI symptoms in a general population study duced by the probiotic Escherichia coli strain
Annikka Polster, Sweden Nissle 1917: Role in visceral hypersensitivity
H. Törnblom, O. Palsson, W. Whitehead, M. Simren Julien Pujo, France
005 IBS brain signature: Cerebral microstructure in
Irritable Bowel Syndrome (IBS)
Eivind Valestrand, Norway P-06 Poster Presentation
T. Hausken, A. Lundervold 12:00 – 13:00 Aula Maxima
006 IBS brain signature: Cortical thickness in the Challenges in severe digestive disorders
salience network Discussant:
Eivind Valestrand, Norway Roberto De Giorgio, Italy Abstracts 001 – 007
T. Hausken, A. Lundervold
001 Correlation between symptoms, quality of life
007 Serum proteomics in African American females
and gastric empting among dyspectic patients
with IBS: A pilot investigation
Guillaume Gourcerol, France
Kristen Weaver, USA
M. Courde, C. Melchior, A. M. Leroi, P. Ducrotté
G. D.´Eramo Melkus, J. Fletcher, W. A. Henderson
002 Prostacyclin reverses colitis through the down
008 miRNA-16 and miR-103 impact 5-HT4 receptor
regulation of intestinal epithelial permeability
signalling and correlate with symptom profile
Camille Pochard, France
in Irritable Bowel Syndrome (IBS)
P. Aubert, C. Gesret, J. Bregeon, N. Cenac, A. B.
Stefanie Schmitteckert, Germany
Bourreille, G. Meurette, M. Neunlist, M. Rolli Der-
C. Wohlfarth, J. D. Härtle, L. Houghton, H. Dweep,
kinderen
M. Fortea, A. Ghazaleh, A. Braun, T. Mederer, P.
Sarina, P. P. Becker, C. Fischer, M. Granzow, H. 003 Inflammatory and oxidative impairment of antral
Mönnikes, E. A. Mayer, G. Sayuk, G. Boeckxstaens, motility in obese patients
M. Wouters, M. Simrén, G. Lindberg, B. Ohlsson, P. Annunziata Scirocco, Italy
T. Schmidt, A. Dlugosz, L. Agreus, A. Andreasson, L. Pallotta, M. Carabotti, G. Silecchia, A. Ignazzi,
M. D‘Amato, B. Burwinkel, J. Lorenzo, R. Röth, F. P. Chirletti, A. Cicenia, M. A. Maselli, E. Corazziari,
Lastischka, M. Vicario, M. Metzger, J. Santos, G. A. C. Severi
Rappold, C. Martinez, B. Niesler
004 Influence of nitizinon on the performance of
009 Comparative expression profiling in rectal bi- mineralexchange in children with type 1 tyros-
opsies of giardia-induced post-infectious IBS: inemia
A pilot study Galina Volynets, Russia
Beate Niesler, Germany A. Khavkin, A. Nikitin, G. Volynets, T. Skvortsova,
C. Martinez, C. Thöni, C. Wohlfarth, K. Hanevik, T. Bushueva
M. Granzow, F. Lasitschka, V. Dizdar, T. Hausken,
005 Dynamics of liver dysfunction in children with
N. Langeland
hereditary tyrosineemia type 1 on the back-
010 Imaging mast cells by confocal microscopy ground of pathogenetic therapy
without fluorescent staining for the diagnosis Galina Volynets, Russia
of Irritable Bowel Syndrome (IBS) A. Nikitin, T. Skvortsova, A. Khavkin, T. Bushueva,
Kang-Nyeong Lee, Republic of Korea A. Nikitin, O. Komarova
I.-K. Sung, O.-Y. Lee, J.-H. Kim, E.-J. Kim, H.-Y. Lee,
006 Peripheral and central nervous system defects
J.-Y. Lee
are associated with altered neuronal projections
011 Global metabolite profiling of multiple sample and early neonatal lethality in a mouse model
types to identify markers for Irritable Bowel of Goldberg-Shprintzen megacolon syndrome
Syndrome (IBS) Lincon Stamp, Australia
Nicole Roy, New Zealand C. Hirst, S. McKeown, A. Bergner, H. Young
K. Fraser, H. Noh, W. Young, R. Gearry
007 The effect of intraperitoneal placenta-derived
012 Single nucleotide polymorphisms in the control mesenchymal stem cell injection in stomachs
region of mitochondrial genome are associated of diabetic mice
with Irritable Bowel Syndrome: A preliminary Sung-Pyo Hong, Republic of Korea
study S.-H. Lee, J.-M. Park, W.-H. Kim, K.-I. Kim, I. K. Sung
Weifeng Wang, China
Z. Li, X. Guo
21ESNM 2017
Poster Presentations / Tours by Day
Friday, 25 August 2017
P-07 Poster Presentation 008 Microbiota-related changes in bile acid and ser-
otonin metabolism are associated with gastroin-
12:00 – 13:00 Aula Maxima testinal dysfunction in a mouse model of autism
Stress and functional gastrointestinal disorders Anna Golubeva, Ireland
Discussants: S. Joyce, G. Moloney, A. Burokas, A. Sherwin, S.
Siobhain O’Mahony, Ireland Abstracts 001 – 006 Arboleya, K. Murphy, N. Hyland, C. Stanton, G.
Serhat Bor, Turkey Abstracts 007 – 012 Clarke, C. Gahan, T. Dinan, J. Cryan
Rene van den Wijngaard,
009 STW 5 prevents changes in intestinal permea-
The Netherlands Abstracts 013 – 017
bility induced by psychological stress in mice
Sigrid Elsenbruch, Germany Abstracts 018 – 022
Michel Neunlist, France
P. Aubert, J. Chevalier, T. Durand, A. Bessard, O.
001 Handling of complex data in neurogastroenter-
Kelber, H. Abdel-Aziz
ology: Multi-step clustering of preclinical data
for a combination phytomedicine, STW 5 010 Irritable Bowel Syndrome (IBS) and associated
Olaf Kelber, Germany health problems: Insights from a primary care
H. Abdel-Aziz, G. Lorkowski, K. Nieber, M. Storr registry
Egbert Clevers, Sweden
002 The prevalence and impact of overlapping Rome
B. Vaes, S. Henrard, G. Goderis, J. Tack, H. Törn-
IV functional gastrointestinal disorders on so-
blom, M. Simrén, L. van Oudenhove
matisation, quality of life, and healthcare uti-
lisation: Results from a three-country general 011 Irritable Bowel Syndrome (IBS) and its comor-
population study bidities: What comes first?
Imran Aziz, Sweden Egbert Clevers, Sweden
O. Palsson, H. Tornblom, A. D. Sperber, W. White- B. Vaes, S. Henrard, G. Goderis, J. Tack, H. Törn-
head, M. Simren blom, M. Simrén, L. van Oudenhove
003 The prevalence of Rome IV functional dyspepsia 012 Within-person correlations between gastrointes-
and its impact on health impairment: Results tinal and psychological features of the Irritable
from a three-country general population study Bowel Syndrome (IBS)
Imran Aziz, Sweden Egbert Clevers, Sweden
O. Palsson, H. Tornblom, A. Sperber, W. Whitehead, J. Tack, H. Törnblom, G. Ringström, L. van Ouden-
M. Simren hove, M. Simrén
004 Stress differentially alters the plasma and brain 013 The effect of intragastric fructose infusion on
metabolomes and caecal microbiome in Wistar homeostatic and hedonic brain regions interacts
Kyoto and Sprague Dawley rats with the effect of emotional state
Shalome Bassett, New Zealand Julie Iven, Belgium
W. Young, K. Fraser, J. Webster, J. Dalziel, L. Ryan, J. Biesiekierski, D. Zhao, J. Tack, L. van Oudenhove
J. Cryan, T. Dinan, C. Stanton, G. Clarke, N. Hyland,
014 Brain-gut miscommunication: Biopsychosocial
N. Roy
predictors of quality of life in IBS
005 The effect of glycoursodeoxycholic acid on epi- Goran Hauser, Croatia
thelial integrity and bacterial uptake in duodenal S. Pletikosic, M. Tkalcic
biopsies of patients with functional dyspepsia
015 Outcome of breath tests in adult patients with
and healthy volunteers
suspected small intestinal bacterial overgrowth
Dorien Beeckmans, Belgium
Johanna Mattsson, Sweden
R. Farré, A. Keita, J. Soderhölm, J. Tack, H. Vanheel
M. T. Minaya, M. Monegro, B. Lebwohl, S. Lewis,
006 Light therapy (LED 940 nm) recovers colonic P. Green, R. Stenberg
motility in experimental colitis of mice
016 Cav3.2 calcium channels: Targets to relieve co-
Paulo Da Silva Watanabe, United Kingdom
lonic hypersensitivity encountered in Irritable
R. Aktar, M. O Belém, L. A. Blackshaw, E. J.A. Araújo
Bowel Syndrome (IBD)
007 Gastroesophageal reflux disease after radiofre- Elodie Picard, France
quency catheter ablation of atrial fibrillation F. A. Carvalho, E. Bourinet, A. Eschalier, L. Daulhac,
Mariana Floria, Romania C. Mallet
O. Barboi, M. Grecu, C. Cijevschi Prelipcean, G.
Balan, V.-L. Drug, V.-L. Drug
22ESNM 2017
Poster Presentations / Tours by Day
Friday, 25 August 2017
017 NUCB2/nesfatin-1 is associated with the severity 003 Effect of faecal microbiota transplantation on the
of eating disorder symptoms in female obese enteroendocrine cells of the colon in patients
patients with Irritable Bowel Syndrome (IBS): Double
Elena Weibert, Germany blinded-placebo controlled study
T. Hofmann, U. Elbelt, M. Rose, A. Stengel Magdy El-Salhy, Norway
P. Holger Johnsen, T. Mazzawi, M. El-Salhy, T.
018 Antibiotic treatment prevents stress-induced
Hausken, R. Goll, P. C. Valle
plasticity in the PVN
Agnieszka Zurek, Canada 004 Co-storage of enteroendocrine hormones eval-
T.-L. Sterley, D. Baimoukhametova, J. Bains uated at the cell and subcellular levels
Linda Fothergill, Australia
019 Evaluating the efficacy of mixture of boswellia car-
B. Callaghan, B. Hunne, D. Bravo, J. Furness
terii, zingiber officinale and achillea millefolium
on severity of symptoms, anxiety and depression 005 Different proton pump inhibitors are equally
in Irritable Bowel Syndrome (IBS) patients effective in inducing endoscopic and histologic
Ali Toghiani, Islamic Republic of Iran remission in patients with proton pump inhibi-
A. Kazemian, K. Shafiei, H. Afshar, R. Rafei, M. tor-response esophageal eosinophilia
Memari, P. Adibi Edoardo Savarino, Italy
S. Tolone, N. de Bortoli, O. Bartolo, V. Savarino,
020 Anhedonia is related to more severe abdominal
M. della Coletta
pain in Irritable Bowel Syndrome (IBS) and In-
flammatory Bowel Disease (IBD) 006 Proximal esophageal baseline impedance levels
Luna Carpinelli, Italy are able to discriminate between scleroderma pa-
C. Bucci, A. Santonicola, F. Zingone, C. Ciacci, P. Iovino tients with and without esophageal involvement
Edoardo Savarino, Italy
021 Homozygous variants in MYLK and LMOD1
P. Zentilin, E. Marabotto, S. Tolone, G. Bodini, N.
cause Megacystis Microcolon Intestinal Hypop-
de Bortoli, V. Savarino, M. della Coletta
eristalsis Syndrome by disruption of smooth
muscle contractility 007 Severe system reactions at children with intol-
Robert Hofstra, The Netherlands erance to fish
D. Halim, E. Brosens, M. Wangler, M. Wilson, J. Anatoly Khavkin, Russia
Verheij, F. Muller, A. Burns, A. Beaudet, J. Miano, N. Esakova, E. Varlamov, A. Pampura, O. Komarova
M. Alves
008 Gluten causes symptom relapse in a small group
022 Stress gone viral: Chronic social stress induces of patients with suspected non-coeliac gluten
marked changes in the gut virome in mice sensitivity: A randomized, double-blind placebo
Veronica Peterson, Ireland controlled challenge
A. Burokas, L. Draper, M. Dalmassso, R. Cabrera-Ru- Jan Gunnar Hatlebakk, Norway
bio, F. Crispie, P. Cotter, T. Dinan, C. Hill, J. Cryan N. Hovdenak, S. Otteraaen Ystad, G. Arslan Lied,
H. Fjeldheim Dale
009 The influence of gluten free diet on the enteric
P-08 Poster Presentation nervous system and intestinal microbiota of mice
12:00 – 13:00 Aula Maxima David Grundmann, Germany
Luminal signalling/ Food allergies and intolerances V. Zevallos, S. Lehnerts, A. Braun, S. Tauchnitz, S.
Discussants: Weis, M. Egert, D. Schuppan, K.-H. Schäfer
Inge Depoortere, Belgium Abstracts 001 – 006 010 Low FODMAP diet improves symptoms and
Catia Sternini, USA Abstracts 007 – 011 quality of life in patients with radiation-induced
small bowel disease: A pilot study
001 Innervation and chemical taxonomy of gastric Trine Larsen, Norway
enteroendocrine cells T. Hausken, S. Ystad, G. Lied, N. Hovdenak, B.
Brid Callaghan, Australia Mueller
B. Hunne, J. Fakhry, F. Linda, S. Ward, K. Sasse,
011 Peculiarities of the upper gastrointestinal tract
J. Furness
motility in children with atopic dermatitis
002 Abnormal stem cells and differentiation prog- Anatoly Khavkin, Russia
eny into enteroendocrine cells in the colon of V. Novikova, A. Listopadova, O. Demchenkova, Y.
patients with IBS Zamyatina
Magdy El-Salhy, Norway
T. Hausken, O. H. Gilja, J. G. Hatlebakk
23ESNM 2017
Poster Presentations / Tours by Day
Friday, 25 August 2017
P-09 Poster Presentation 010 Chronic gut leakiness induces gender-specific
neurobehavioral alterations in transgenic CA-
12:00 – 13:00 Aula Maxima MLCK mice
Mixed topics Marion Rincel, France
Discussants: L. Xia, C. Monchaux de Oliveira, J. Thomas, V. Bac-
David Grundy, United Kingdom Abstracts 001 – 005 quie, L. Gros, A. Dinca, S. Barnett Burns, Y. Matime,
André Smout, The Netherlands Abstracts 006 – 010 J. Turner, L. Capuron, V. Théodorou, L. Ferrier, M.
Adam Farmer, United Kingdom Abstracts 011 – 015 Darnaudéry
Ihsan Ekin Demir, Germany Abstracts 016 – 021
011 Wireless optogenetics: Development of simul-
taneous activation of multiple light emitting
001 Cost effective of IBDoc as a surrogate marker of
mucosal healing in IBD patients post induction diodes (green and blue) for activation or inhi-
of biological agents bition of multiple different neural pathways
Gafer Elsafi, Ireland Nick Spencer, Australia
L. Barry, K. Sugrue, M. Farman, D. Fitzgerald, A. 012 Influence of dimethyl fumarate on murine post-
Alhanaee, M. Buckley, J. McMarthy operative ileus
002 Acute tryptophan depletion increases esopha- Jonas van Dingenen, Belgium
geal sensitivity to acid perfusion in health R. A. Lefebvre
Charlotte Broers, Belgium
013 Investigation to prevent postoperative ileus via
B. van Houtte, P. Vermeersch, N. Peersman, J. Tack,
A. Pauwels peroral CO
Jonas van Dingenen, Belgium
003 Effect of faecal microbiota transplantation on C. Steiger, M. Zehe, L. Meinel, R. A. Lefebvre
the symptoms and gut microbiota in patients
with Irritable Bowel Syndrome (IBS) 014 Innervation pattern of the distal mucosal squa-
Trygve Hausken, Norway mous epithelium may underlie hyposensitivity to
T. Mazzawi, G. Arslan Lied, D. A. Sangnes, J. E. acid reflux in patients with Barrett‘s oesophagus
Roksund Hov, O. H. Gilja, J. G. Hatlebakk, M. El-Salhy Philip Woodland, United Kingdom
F. Grassi, J. Evans, S. McDonald, M. Peiris, R. Aktar,
004 The levels of pantoprazole in human breast milk
and plasma: Two compartment model J. Ooi, C. Lee, L. A. Blackshaw, D. Sifrim
Pelin Ergun, Turkey 015 Melanin-concentrating hormone receptor 1 ex-
S. Bor, S. Karacaoglu, S. Kipcak, G. Turkyilmaz, pression in colon: A multiplex immunohistochem-
E. Karasulu ical study with colon from „normal“ donors and
005 Validation of the Korean version of the GerdQ patients with Inflammatory Bowel Disease (IBD)
questionnaire for diagnosis of gastro-esophageal Nicholas Barnes, United Kingdom
reflux disease S. Yusoff, G. Grafton, T. Pinkney
Kee-Wook Jung, Republic of Korea
016 Tickling the 5-HT3 receptor: Potential therapeu-
Y.-W. Min, K.-S. Hong, H.-J. Son, O.-Y. Lee
tic opportunities for patients with diarrhea-pre-
006 Pathogenic mechanisms of esophageal peristaltic dominant Irritable Bowel Syndrome (IBS) from
dysfunction by high resolution manometry in the selective 5-HT3 receptor partial agonist,
patients with systemic sclerosis CSTI-300
Joon-Seong Lee, Republic of Korea Nicholas Barnes, United Kingdom
007 Anti-inflammatory mechanisms of action in FD A. Roberts, G. Grafton, Y. Mo, D. Meng, D. Xie, S.
and IBS: The example of STW 5 Liu, P. Guzzo
Olaf Kelber, Germany
017 Radiocontrast media guided interpretation for
K. Nieber
lactulose hydrogen breath test
008 Inflammatory conditions favor the interactions Jong-Sun Rew, Republic of Korea
between T cells and enteric glial cells S.-Y. Park, S.-W. Park, S.-W. Park, J.-H. Seo, E.-A.
Julie Pabois, France Cho, C.-H. Park, H.-S. Kim
T. Durand, J. A. Gonzales, M. Neunlist, I. Neveu,
P. Naveilhan 018 NDRG4 is an enteric neuronal protein which
attenuates intestinal tumor progression and
009 Parasympathomimetic agents inhibit pancreatic protects against colitis-induced injury
cancer growth by suppression of the p44/42 MAPK
Nathalie Vaes, The Netherlands
signalling pathway and increase overall survival
V. Melotte, G. Rademakers, M. J. Gijbels, K. L. Dae-
Paulo Leonardo Pfitzinger, Germany
I. E. Demir, E. Tieftrunk, K. Wang, H. Friess, G. nen, K. A. D. Wouters, R. M. W. Hofstra, M. van
O. Ceyhan Engeland
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