11 NOVIEMBRE 2021 RESULTADOS DE LA ENCUESTA TRIPARTITA DE AUTOEVALUACIÓN DE LOS PAÍSES SOBRE LA RAM (TRACSS) 2021 PARA LOS INDICADORES DE SALUD HUMANA

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11 NOVIEMBRE 2021 RESULTADOS DE LA ENCUESTA TRIPARTITA DE AUTOEVALUACIÓN DE LOS PAÍSES SOBRE LA RAM (TRACSS) 2021 PARA LOS INDICADORES DE SALUD HUMANA
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                                Resultados de la encuesta tripartita de
                                autoevaluación de los países sobre la RAM
                                (TrACSS) 2021 para los indicadores de salud
                                humana

                                   11 noviembre 2021

Dra. Pilar Ramon-Pardo
Coordinadora
Programa Especial de Resistencia a los Antimicrobianos
OPS/OMS
11 NOVIEMBRE 2021 RESULTADOS DE LA ENCUESTA TRIPARTITA DE AUTOEVALUACIÓN DE LOS PAÍSES SOBRE LA RAM (TRACSS) 2021 PARA LOS INDICADORES DE SALUD HUMANA
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   LÍNEAS ESTRATÉGICAS PLAN DE ACCIÓN GLOBAL

1. Mejorar la concientización y la comprensión;
2. Reforzar los conocimientos a través de la vigilancia y la
   investigación;
3. Reducir la incidencia de las infecciones;
4. Utilizar de forma óptima losantimicrobianos; y
5. Asegurar una inversión sostenible.

        WHO, 2015. Global Action Plan on Antimicrobial Resistance.
        http://apps.who.int/iris/bitstream/10665/193736/1/9789241509763_eng.pdf?ua=1
11 NOVIEMBRE 2021 RESULTADOS DE LA ENCUESTA TRIPARTITA DE AUTOEVALUACIÓN DE LOS PAÍSES SOBRE LA RAM (TRACSS) 2021 PARA LOS INDICADORES DE SALUD HUMANA
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                 Participación de la OMS         Tasas de respuesta TrACSS
                                                        2021, N (%)

                 Global (N=194)                           163 (84%)
                 AFR, 41                                  41 (87%)
                 AMER, 35                                 23 (66%)

Tasas de         EMR, 21                                  21 (100%)

participación
                 EUR, 53                                  50 (94%)
                 SEAR, 11                                 11 (100%)

en TrACSS 2021
                 WPR, 27                                  17 (63%)

                            Tasas de respuesta de TrACSS en los
                                       últimos 5 años
                                        79%       82%                   84%
                 100%         78%
                                      (n=154)   (n=159)      70%      (n=163)
                            (n=151)
                  80%                                      (n=136)
                  60%
                  40%
                  20%
                   0%
                            2017       2018      2019      2020        2021
11 NOVIEMBRE 2021 RESULTADOS DE LA ENCUESTA TRIPARTITA DE AUTOEVALUACIÓN DE LOS PAÍSES SOBRE LA RAM (TRACSS) 2021 PARA LOS INDICADORES DE SALUD HUMANA
COVID-1 9 y RAM
                                                                         Aumento de vulnerabilidad                                       4
                                                                         en los pacientes:
                                                                         enfermedades subyacentes y
                                                                         factores de riesgo

                                                                              9 Nov 2021

                                                                         -Inicialmente, sobreinfecciones bacterianas en el 50% de
                                                                         las muertes por COVID-19.
                                                                         -Uso de antibióticos (94% -100%) más alto que la
                                                                         incidencia informada de infección secundaria (7 - 10% ).
                                                                         - Durante la pandemia de COVID-19, los hospitales están
                                                                         sobrecargados.
                                                                             -Impacto en las infecciones asociadas a la atención de la salud.
                                                                         -Ensayos clínicos con azitromicina e hidroxicloroquina
Fuente foto: https://www.nbcnews.com/news/latino/chile-hospital-gives-
covid-19-patients-families-rare-chance-say-n1231870
11 NOVIEMBRE 2021 RESULTADOS DE LA ENCUESTA TRIPARTITA DE AUTOEVALUACIÓN DE LOS PAÍSES SOBRE LA RAM (TRACSS) 2021 PARA LOS INDICADORES DE SALUD HUMANA
Impacto de la COVID-1 9 en los PNA de RAM                                                                                                         5

                                                                      % of countries responding ‘YES’
                                    0%   10%         20%        30%      40%       50%        60%       70%   80%          90%          100%

                                                                                                                                  93%
          Covid impact AMR NAPs
                                                                                                                                           100%

    Governance and administrative                                                                                    82%

              impacts                                                                                                            91%

                                                                                                               79%
              Operational impacts
                                                                                                               78%

                                               Global (n=163)   AMER (n=23)
Planes de Acción Nacionales sobre la RAM                                                                                                                 6

                                                                            Progreso de los PAN

                                           50%

                                                                                                                  39%
                                           40%                                                                   (39%)                                     ¡Trabajo en progreso!
Responding countries at each level % (N)

                                                                       30% (7)
                                                                                            28%
                                           30%                                                                               26%
                                                                                            (45)
                                                                                                                              (6)
                                                                                                       22%                                     22%
                                                                                                        (5)                         20%         (5)
                                                                                                                                    (32)
                                           20%

                                                                                                                                                      A No national AMR action plan.
                                                                11%
                                                                (18)                                                                                  B National AMR action plan under development.
                                           10%                                                                                                        C National AMR action plan developed.
                                                 3%                                                                                                   D   National AMR action plan being implemented.
                                                 (5)
                                                                                                                                                      E   National AMR action plan being implemented and actively
                                                           0%
                                           0%                                                                                                             monitored through a monitoring and evaluation
                                                                                                                                                          framework.
                                                       A               B                           C                     D                 E

                                                                           Global (n=163)          AMER (n=23)
PNA RAM: vínculos con sectores y otros temas de salud
                                                                                                                                                                               7

                                                                                           PNA vinculados a estrategias/planes de acción de
                          Sectores que participan                                                       otros temas de salud
                                                                                                            AMER (n=23)     Global (n=163)
                            AMER (YES)     Global (YES)
                                                                                         AMR NAP linked with other…                                                    70%
                                                                                                                                                                 61%
        Human                                                                100%
        Health                                                               100%

                                                                                         National Food Safety/Food…                                                65%
         Animal                                                                                                                                      40%
                                                                             96%
         Health                                                              96%                                  TB                                       52%
                                                                                                                                                    38%

                                                                                                                 HIV                                       52%
                                                                       87%                                                                     33%
    Food Safety
                                                                 79%                                                                            35%
                                                                                                     Health Security                          31%
    Environmen                                          65%                                                   WASH                                  39%
                                                                                                                                          28%
         t                                              64%
                                                                                     Sexually Transmitted Infections                                       52%
                                                                                                                                         26%
        Food                                             65%                                                                             26%
                                                       61%
                                                                                                      Immunization                       26%
     Production
                                                                                                             Malaria                          30%
                                                                                                                                        23%
                                                               74%
    Plant Health                                                                                                                       22%
                                               50%                                     National Environmental plans                    21%

                                                                                    NTD- Neglected Tropical Diseases                     26%
                   0%       20%      40%         60%           80%       100%                                               9%
                        Percentage of countries responding ‘YES’                                                       0%        20%            40%         60%          80%

                                                                                                                Percentage of countries responding ‘YES’
8

                                             Grupos de Trabajo Multisectoriales

                                       80%

                                       70%

                                                                                                                                          ¡Trabajo en progreso!
Responding countries at each level %

                                                                     61%
                                       60%

                                       50%
                                                           42%
                                       40%

                                       30%                                                                                          26%   A No formal multi-sectoral governance or coordination
                                                                                                                                            mechanism on AMR exists.
                                                                                                                          22%
                                                                                                                                          B   Multi-sectoral working group(s) or coordination committee on
                                       20%
                                                                                       15%                                                    AMR established with Government leadership.
                                                                                                           13%
                                                                                                                                          C   Multi-sectoral working group(s) is (are) functional, with clear
                                             8%       9%
                                       10%                                                                                                    terms of reference, regular meetings, and funding for working
                                                                                                 4%                                           group(s) with activities and reporting/accountability
                                                                                                                     0%                       arrangements defined.
                                       0%
                                                                                                                                          D Joint working on issues including agreement on common
                                                  A              B                           C                   D              E
                                                                                                                                            objectives.
                                                                                                                                          E   Integrated approaches used to implement the national AMR
                                                                      Global (n=163)         AMER (n=23)                                      action plan with relevant data and lessons learned from all
                                                                                                                                              sectors used to adapt implementation of the action plan.
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Objetivo 1 – Aumentar la concientizacion frente a la RAM

                                                           AMR awareness raising campaigns

                                       80%

                                       70%
Responding countries at each level %

                                       60%
                                                                                            52%
                                       50%                                        47%

                                       40%

                                                                                                      29%
                                       30%                                                                      26%
                                                                                                                                     A No significant awareness-raising activities on relevant aspects of risks of
                                                                                                                                       antimicrobial resistance.
                                       20%
                                                                                                                                     B Some activities in parts of the country to raise awareness about risks of
                                                                                                                      10%               antimicrobial resistance and actions that can be taken to address it.
                                                      9%   9%       9%
                                       10%                                                                                           C Limited or small-scale antimicrobial resistance awareness campaign
                                             4%                                                                                 4%
                                                                                                                                        targeting some but not all relevant stakeholders.

                                       0%                                                                                            D Nationwide, government-supported antimicrobial resistance awareness
                                                  A             B                       C                   D               E          campaign targeting all or the majority of priority stakeholder groups,
                                                                                                                                       based on stakeholder analysis, utilizing targeted messaging accordingly
                                                                     Global (n=163)     AMER (n=23)                                    within sectors.
                                                                                                                                     E Targeted, nationwide government-supported activities regularly
                                                                                                                                       implemented to change behavior of key stakeholders within sectors,
                                                                                                                                       with monitoring undertaken over the last 2-5 years.
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                                                           Objetivo 1 : Formación y educación sobre RAM

                                                  Training and education on AMR in human helath sector

                                       80%

                                                                                               70%
                                       70%
Responding countries at each level %

                                       60%
                                                                                     53%
                                       50%

                                       40%
                                                                                                                                      A   No training for AMR.

                                       30%                                                                                                Ad hoc AMR training courses.
                                                                                                                                      B
                                                                                                                                          AMR is covered in curricula of some pre-service training and in 2)
                                                              19%                                                                         some in-service training or other continuing professional
                                       20%                                                               17%
                                                                                                                                      C   development (CPD) for human health workers.
                                                                        13%
                                                                                                                   9%   9%       9%
                                       10%
                                                                                                                                          AMR is covered in pre-service training for all relevant cadres. In-
                                             1%                                                                                           service training or other CPD covering AMR is available for all types of
                                                      0%                                                                              D   human health workers nationwide.
                                       0%
                                                  A                 B                      C                   D             E
                                                                                                                                          AMR is systematically and formally incorporated in pre-service
                                                                                                                                          training curricula for all relevant human health cadres. In-service
                                                                    Global (n=161)         AMER (n=23)                                    training or other CPD on AMR is taken up by relevant groups for
                                                                                                                                      E
                                                                                                                                          human health nationwide, in public and private sectors.
Objetivo 2 – Monitoreo del uso/venta de antimicrobianos                                                                                                               11

                                                             National monitoring system for antimicrobial use
                                                                            in human health
                                       60%

                                       50%
Responding countries at each level %

                                       40%

                                                       30%
                                       30%
                                                                                                         26%                                       A No national plan or system for monitoring use of antimicrobials.
                                             23%                                                                                   23%               System designed for surveillance of antimicrobial use, that includes
                                                                   22%                                                       22%
                                                                                               20%
                                       20%
                                                                                                                                                   B monitoring national level sales or consumption of
                                                                                                                                                     antibiotics in health services.

                                                                                                                                             13%     Total sales of antimicrobials are monitored at national level and/or some
                                                                                                                   12%
                                                                                                                                                   C monitoring of antibiotic use at sub-national
                                       10%                                   9%                                                                      level.

                                                                                                                                                      Prescribing practices and appropriate antibiotic use are monitored in a
                                                                                                                                                   D national sample of healthcare settings.

                                       0%                                                                                                             On a regular basis (every year/two years) data is collected and reported
                                                   A                     B                           C                   D               E            on:
                                                                                                                                                     a)     Antimicrobial sales or consumption at national level for human use;
                                                                                                                                                   E
                                                                              Global (n=163)         AMER (n=23)                                            and
                                                                                                                                                     b)     Antibiotic prescribing and appropriate/rational use, in a
                                                                                                                                                            representative sample of health facilities, public and private.
12
                                             Objetivo 2 – Vigilancia de la RAM en la salud humana

                                                               National AMR surveillance systems
                                                                        in human health
                                       80%

                                       70%
Responding countries at each level %

                                       60%

                                       50%                                                                           48%
                                                                                                           43%

                                       40%
                                                                                                 35%                                         No capacity for generating data (antibiotic susceptibility testing and
                                                                                                                                          A accompanying clinical and epidemiological data) and reporting on
                                       30%                                                                                                  antibiotic resistance.
                                                                                                                                            AMR data is collated locally for common bacterial infections in
                                                               23%                                                                          hospitalized and community patients, but data collection may not
                                                                                       19%                                                B
                                       20%   ,                                                                                              use a standardized approach and lacks national coordination and/or
                                                                         13%                                                                quality management.
                                                                                                                           11%              AMR data are collated nationally for common bacterial infections in
                                       10%                                                                                                C hospitalized and community patients, but national coordination and
                                                 3%                                                                                  4%     standardization are lacking.
                                                          0%                                                                                There is a standardized national AMR surveillance system collecting
                                       0%                                                                                                   data on common bacterial infections in hospitalized and community
                                                      A              B                       C                   D               E        D patients, with established network of surveillance sites, designated
                                                                                                                                            national reference laboratory for AMR,, and a national coordinating
                                                                          Global (n=159)     AMER (n=23)                                    centre producing reports on AMR.
                                                                                                                                            The national AMR surveillance system links AMR
                                                                                                                                          E surveillance with antimicrobial consumption and/or use
                                                                                                                                            data for human health.
Objetivo 2 – Red de laboratorios de RAM en salud humana                                                                                                                                                                       13
(nueva pregunta en 2021 TrACSS) -

                                                              National AMR lab network
                                            80%
                                                                                                                                                                      National lab structure
     Responding countries at each level %

                                            70%                                                                                                                                       0%      20%         40%   60%         80%         100%
                                            60%
                                                                                                                        48%
                                            50%                                                                                Majority of bacteriology laboratories in the public
                                                                                                                              health sector part of a National Laboratory network                         78%                     22%     0%
                                            40%                                                                                                       (n=23)
                                                                                                              33%
                                            30%                                                   25%
                                                              18%
                                            20%                                  14% 13%
                                                        13%             13%                             13%
                                                  10%
                                            10%                                                                                     Regulatory authority exists to certify/accredit
                                                                                                                                                                                                        70%                  30%          0%
                                                                                                                                          bacteriology laboratories (n=23)
                                            0%
                                                    A               B               C               D               E

                                                                Global (n=158)      AMER (n=23)

                                                                                                                              Regulatory authority exists to provide accreditation
A   Information not available.                                                                                                 based on International Standards for Bacteriology                    56%               31%          13%
    The National Reference Laboratory (NRL) and/or the National Regulatory Authority                                                         Laboratories (n=16)
B   (NRA) has not agreed and approved national guidelines for AST (e.g CLSI or EUCAST),
    bacterial isolation and identification protocols
    The NRL and/or NRA have issued national guidelines, based on international standards
C   for AST (e.g CLSI or EUCAST), bacterial isolation and identification for use within the
    bacteriology laboratory network.
                                                                                                                                                                          Yes     No       Don't Know
    The NRL and/or NRA have issued national guidelines for AST (e.g CLSI or EUCAST),
    bacterial isolation and identification for use within the bacteriology laboratory network
D   and National Reference Laboratory participates in an international external quality
    assurance.
    The National Reference Laboratory supports the bacteriology laboratory network in
    identification of pathogens and AMR through a systematic approach to cascade training
E   and supportive supervision and it has established a National External Quality Assurance
    program provided to the national bacteriology laboratory network.
14
    Utilización de datos pertinentes sobre el consumo/uso de
antimicrobianos y/o la RAM para modificar la estrategia nacional
                     en los siguientes sectores

                            0%        10%          20%      30%         40%      50%       60%   70%         80%   90%   100%

                                                                                                 67%
           Human Health                                                                                73%

                                                                                   50%
            Animal Health                                                                55%

                                            12%
             Plant Health                         16%

                                                          26%
          Food Production                                         33%

                                                                        38%
              Food Safety                                                        47%

                                      7%
             Environment         0%

                                                         Global (Yes)         AMER (Yes)
15

                                       Objetivo 3- Reducir la RAM en la salud humana
                                                             Programa nacional de la PCIP

                                       80%

                                       70%
                                                                                                                                               ¡Trabajo en progreso!
Responding countries at each level %

                                       60%
                                                                                                  52%
                                       50%

                                       40%
                                                                                        32%                                                A No national IPC programme or operational plan is available.
                                       30%                            26%                                                                      A national IPC programme or operational plan is available.
                                                                                                                                               National IPC and water, sanitation and hygiene (WASH) and
                                                            22%                                                                            B
                                                                                                                           19%                 environmental health standards exist but are not fully
                                       20%                                                                                                     implemented.
                                                                                                            15%
                                                                                                                                     13%       A national IPC programme and operational plan are available and
                                             11%                                                                                               national guidelines for health care IPC are available and
                                       10%                                                                                                 C
                                                                                                                                               disseminated. Selected health facilities are implementing the
                                                       4%                                                             4%                       guidelines, with monitoring and feedback in place.
                                                                                                                                               National IPC programme available according to the WHO IPC core
                                        0%                                                                                                     components guidelines and IPC plans and guidelines implemented
                                                   A              B                           C                   D              E         D   nationwide. All health care facilities have a functional built
                                                                                                                                               environment (including water and sanitation), and necessary
                                                                                                                                               materials and equipment to perform IPC, per national standards.
                                                                       Global (n=162)         AMER (n=23)                                      IPC programmes are in place and functioning at national and
                                                                                                                                               health facility levels according to the WHO IPC core components
                                                                                                                                           E   guidelines. Compliance and effectiveness are regularly evaluated
                                                                                                                                               and published. Plans and guidance are updated in response to
                                                                                                                                               monitoring.
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Objetivo 4 – Optimizar el uso de antimicrobianos en
la salud humana
                                              Políticas para optimizar el uso de antimicrobianos en la salud humana

                                        80%

                                        70%
 Responding countries at each level %

                                                                                                      61%
                                        60%

                                        50%

                                                                                            39%
                                        40%

                                        30%                                                                     27%       26%                 A No/weak national policies for appropriate use.
                                                                                                                                                 National policies for antimicrobial governance
                                                                                                                                              B developed for the community and health care
                                        20%
                                               16%                                                                                              settings.
                                                                13%                                                                             Practices to assure appropriate antimicrobial use
                                        10%                                                                                                     being implemented in some healthcare facilities and
                                                                                                                                6%            C
                                                         4%               4%                                                             4%     guidelines for appropriate use of antimicrobials
                                                                                                                                                available.
                                        0%                                                                                                      Guidelines and other practices to enable appropriate
                                                     A                B                           C                   D              E          use are implemented in most health facilities
                                                                                                                                              D nationwide. Monitoring and surveillance results are
                                                                                                                                                used to inform action and to update treatment
                                                                           Global (n=161)         AMER (n=23)                                   guidelines and essential medicines lists.
                                                                                                                                                Guidelines on optimizing antibiotic use are
                                                                                                                                              E implemented for all major syndromes and data on
                                                                                                                                                use is systematically fed back to prescribers.
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                                              Objetivo 4 – AWaRe en la lista nacional de
                                              medicamentos esenciales
                                                                                                                                                         ¡Trabajo en progreso!
                                                             Adopción de AWaRe en LME nacional
                                       80%

                                       70%

                                       60%
Responding countries at each level %

                                                                53%

                                       50%
                                                                          43%

                                       40%

                                       30%

                                                                                                     22%
                                                                                           20%
                                       20%             17%                                                                                      Country has no knowledge or information about the AWaRe
                                                                                                                                            A
                                                                                                                                                classification of antibiotics.
                                             11%                                                                             10%                Country has knowledge about the AWaRe classification of
                                       10%                                                                              9%             9%   B   antibiotics and country has intention to adopt it in the next
                                                                                                               6%
                                                                                                                                                few years.
                                                                                                                                                Country has adopted the AWaRe classification of antibiotics
                                                                                                                                            C
                                                                                                                                                in their National Essential Medicines List.
                                       0%
                                                                                                                                                Country is monitoring its antibiotic consumption based on
                                                   A                  B                          C                  D              E        D
                                                                                                                                                the AWaRe classification of antibiotics.
                                                                                                                                                Country has incorporated AWaRe classification of antibiotics
                                                                          Global (n=161)         AMER (n=23)                                E
                                                                                                                                                into its antibiotic stewardship strategies.
18
Regulaciones en el uso de antimicrobianos (ventas y uso)

                                                                                                                                  Yes        No        Don't Know

                                                                                       0%   10%   20%   30%     40%         50%     60%       70%       80%         90%        100%

      Laws/regulations on prescription and sale of antimicrobials for human use.                                      91%                                                 9%      0%

      Laws/regulations on prescription and sale of antimicrobials for animal use.                             74%                                             22%          4%

                                     Prohibit antimicrobials for growth promotion                 39%                                      57%                             4%

Legislation on marketing of pesticides, including antimicrobial pesticides, in plant
                                                                                                              74%                                     9%            17%
                                    production

                                                                                                                             Source: TrACSS 2021 data n=23
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                                              PAHO/WHO

                    Reflexiones hacia TraCSS 2023

     Datos confiables para el uso                     Oportunidades de mejora
     • Herramienta para la abogacia               - Mejorar la tasa de respuesta
     • Datos para el desarrollo de políticas y    - Mejorar la calidad de las respuestas,
         líneas de cooperación técnica                   que reflejen la situacion real de los
     •   Oportunidad de discusión sobre los              paises (Una Salud, multisectorial,
         avances y desafíos del país                     metodología)
                                                  -      Estandarizar la comprensión de las
                                                         preguntas y respuestas (intra e inter)
                                                  -      Apoyo de los colegas de FAO y OIE
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