2nd International Congress of the World Association for Stress Related and Anxiety Disorders

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2nd International Congress of the World Association for Stress Related and Anxiety Disorders
www.wasad2019.org

2nd International Congress of the
World Association for Stress Related
and Anxiety Disorders
in conjunction with the
Collaborative Research Center SFB TRR 58,
Fear, Anxiety, Anxiety Disorders (funded by the DFG)
Stress, Anxiety and Mental Health

03-05 October 2019

Würzburg, Germany

Final Program
2nd International Congress of the World Association for Stress Related and Anxiety Disorders
Congress Information

Congress Venue
Julius-Maximilians-Universität Würzburg Building Z6
Hubland Süd (Zentrales Hörsaal- u. Seminargebäude)
Am Hubland
97074 Würzburg, Germany

Host Organization
World Association for Stress Related and Anxiety Disorders (WASAD)
Schwanenhof 4, 97070 Würzburg, Germany
Phone: +49 (0) 931 – 207 90248; Fax: + 49 (0) 931 – 207 90246
info@wasad.de

Affiliate Organizer
SFB-TRR 58 Fear, Anxiety, Anxiety Disorders
Institut für Physiologie I, Robert-Koch-Straße 27, 48149 Münster, Germany

Congress Presidents
Prof. Dr. H. C. Pape, Germany; Prof. Dr. A. J. Fallgatter, Germany

Local Organizing Committee
Chairs: M. Gamer and P. Riederer, Germany
J. Deckert, Germany; M. Gamer, Germany; P. Pauli, Germany; P. Riederer, Germany;
M. Romanos, Germany

Scientific Committee
Chairs: H. C. Pape and A. J. Fallgatter, Germany
Scientific Committee WASAD
E. Binder, Germany, A.J. Fallgatter, Germany, J. Fayyad(†), Beirut, C. Jacob, Germany, J. Li, China,
H. Ozawa, Japan, A. Reif, Germany, T. Renner, Germany, P. Riederer, Germany, E. Seifritz,
Switzerland, S. Walitza, Switzerland
Scientific Committee SFB-TRR 58
C. Büchel, Germany, U. Dannlowski, Germany, K. Domschke, Germany, J. Haaker, Germany, C.
Heim, Germany, M. Gamer, Germany, K. Jüngling, Germany, H.C. Pape, Germany, P. Pauli,
Germany

2
2nd International Congress of the World Association for Stress Related and Anxiety Disorders
Congress Information

Session formats
Keynote Lectures
Keynote lectures of 60 minutes will be given by a distinguished and renowned expert and will
be devoted to a specific topic of major interest.
Symposia
These sessions of 90 minutes will focus on a particular topic and present the very latest data
related to it. The symposia will include four speakers who present their research followed by
discussion. These sessions will combine presentations by invited speakers and the best
submitted papers accepted for the congress by the scientific committees.
Posters
Authors present their latest research findings or ongoing research as posters.
Industry Sponsored Sessions
Industry sponsored sessions of 60 minutes are organized by the industry in consultation with
the scientific committee.

Information for speakers:
We kindly ask all speakers to come to their assigned room 15 minutes before the session starts.
Please have your presentation ready in MS Powerpoint format on a USB stick. Please do not
bring your own laptop.
Someone will be available to assist you with uploading your presentation.

Information for poster presenters:
We kindly ask all poster presenters to mount their poster on
       Thursday, October 3rd, 13.15 - 17.00 or on Friday, October 4th, 08.15 - 11.00.
Assistance and mounting material (poster strips) are available.
Please see detailed program (p. 10) for the time you are requested to be present at your poster.
The posters can remain on display until Saturday, October 5th, 18.30 (removal by the author is
possible on Saturday afternoon), and will be removed by the organizers afterwards.
Three posters will be selected for a WASAD Poster Award (Award Ceremony during Closing
Session).

Rooms:
HS 0.001, HS 0.002 - ground floor
SR 1.012, SR 1.003 - 1st floor

CME points:
The scientific program of the congress is certified by the Bayerische Landesärztekammer (BLÄK)
with 22 CME points. Certificates can be obtained at the registration desk.

Please note that only presenting authors are stated in the program due to space restrictions. All
authors will be named in the printed abstracts.

                                                                                               3
2nd International Congress of the World Association for Stress Related and Anxiety Disorders
Program overview

Thursday
         HS 0.001                HS 0.002                SR 1.012             SR 1.003
Oct 3rd

14.00-                           Opening ceremony,
14.30                            Welcome addresses

          New insights into      Clinical perspectives
                                                         Imaging of stress-
15.00-    (dys-) regulation of   in the treatment of
                                                         induced brain
16.30     fear and anxiety in    anxiety disorders
                                                         functional changes
          rodents                (GAF-Symposium)

17.00-    Keynote lecture by
18.00     Rachel Yehuda

18.00-
          Welcome reception at the congress venue
20.00

Friday
          HS 0.001               HS 0.002                SR 1.012             SR 1.003
Oct 4th

09.00-    Keynote lecture by
10.00     Mathias Schmidt

                                                                              Mapping
                                                                              mechanisms of gene
10.30-    How anxiety            Stress resilience and                        x environment
12.00     modulates attention    vulnerability                                interaction in stress -
                                                                              from endophenotype
                                                                              to disease

12.15-
                                                         Industry symposium
13.15

13.30-    Keynote lecture by
14.30     Martin Paulus

                                                                              15.30-16.30:
14.30-
          Poster session                                                      WASAD General
17.00
                                                                              Assembly

          Anxiety Disorders -
17.00-    Prediction,
                               Stress and dementia                            SGAD Symposium
18.30     prevention and
          personalized therapy

4
2nd International Congress of the World Association for Stress Related and Anxiety Disorders
Program overview

Saturday
         HS 0.001              HS 0.002              SR 1.012               SR 1.003
Oct 5th

09.00-   Keynote lecture by
10.00    Brenda Penninx

                                                     Clinical targets for
                               Temperament, gene
         Individual                                  stress related and
10.30-                         and nutrition in
         differences in fear                         anxiety disorders in
12.00                          anxiety and related
         and anxiety                                 children and
                               disorders
                                                     adolescents

12.15-                                                                      Meeting of SFB TRR
                               Industry symposium
13.15                                                                       58 members

13.30-   Keynote lecture by
14.30    Thomas Kash

                               (Maternal) Stress
                                                     Anxiety, depression
15.00-   Neural dynamics of    and its
                                                     and cognition in
16.30    aversive learning     consequences: from
                                                     brain and heart
                               animals to humans

         Telemedicine and
                              Anxiety: genetics,     Adult ADHD and
17.00-   mobile assessment in
                              social interactions    stress: cause or
18.30    stress related
                              and therapy            consequence?
         disorders

18.45-
                               Closing ceremony
19.00

                                                                                                 5
2nd International Congress of the World Association for Stress Related and Anxiety Disorders
Welcome address

Dear colleagues,

The World Association for Stress-Related and Anxiety Disorders (WASAD) aims to promote basic
research and to foster effective and safe treatments and prevention strategies for mental
illnesses related to abundant stress and anxiety. Such illnesses include depression, panic
disorders, social anxiety disorders, specific phobias or separation anxiety disorders, PTSD,
ADHD, sleep disorders and others. These are the most prevalent mental disorders and they are
definitely related to increased levels of stress and associated with immense health care costs
and a high burden of disease.

According to large population-based surveys, roughly one third of the population is affected by
an anxiety disorder during their lifetime. Substantial underrecognition and undertreatment of
these disorders have been shown and recent efforts underline the importance of resilience.
Untreated, stress related and anxiety disorders frequently follow a chronic course, and they are
highly comorbid with other mental disorders, in particular with affective and substance abuse
disorders. While research on pathophysiological mechanisms as well as diagnosis and treatment
made substantial progress during the last years, translation into clinical practice is still lacking
behind.

At this joint conference, WASAD and the "SFB-TRR 58, Fear, Anxiety, Anxiety Disorders” offer a
total of 23 scientific sessions addressing those problems and provide a forum for scientists,
clinicians, practicing physicians, psychotherapists, PostDocs and PhDs, students and other
health care professionals to exchange knowledge and experiences in the fields of basic and
clinical research and to transfer this information into successful clinical applications for the
benefit of our patients.

In this sense, we wish you all a fruitful and stimulating conference!

Yours sincerely,

Prof. Dr. Peter Riederer      Prof. Dr. Andreas J. Fallgatter       Prof. Dr. Hans-Christian Pape
President WASAD               Vice-President WASAD                  Coordinator SFB-TRR 58
                              and Congress President                and Congress President

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2nd International Congress of the World Association for Stress Related and Anxiety Disorders
Scientific Program – Thursday, October 3rd

14.00 - 14.30 | Opening Ceremony

HS 0.002
Welcome Addresses
Alfred Forchel, President, University of Würzburg
Matthias Frosch, Dean, Faculty of Medicine, University of Würzburg
Andreas Fallgatter, Congress President
Hans Christian Pape, Congress President
Peter Riederer, President WASAD

15.00 - 16.30 | Parallel Sessions

HS 0.001
SFB Symposium | New insights into (dys-) regulation of fear and anxiety in rodents
Chair: Andreas Draguhn, Heidelberg, and Hans-Christian Pape, Münster

                               Studying neural mechanisms of stress vulnerability and
 15.00     Gal Richter-Levin
                               resilience in an animal model of PTSD
                               Brainstem circuits mediating behavioral and autonomic
 15.20     Philip Tovote
                               defensive states
                               Novel vistas on Neuropeptide S-mediated fear regulation from
 15.40     Kay Jüngling
                               a humanized mouse model
                               Encoding of social information by subpopulations of amygdala
 16.00     M. S. Fustiñana
                               neurons

HS 0.002
WASAD Symposium | Clinical perspectives in the treatment of anxiety disorders
                       (Symposium of the GAF)
Chair: Katharina Domschke, Freiburg, and Peter Zwanzger, Wasserburg

                               D-cycloserine (DCS) adjunct treatment in combination with
 15.00     Andreas Ströhle
                               cognitive behavioral therapy (CBT)

 15.20     Miriam Schiele      Prevention of anxiety disorders

                               Non-invasive brain-stimulation and its impact on extinction
 15.40     Martin Herrmann
                               learning

 16.00     Julia Diemer        Virtual reality as a new tool for the treatment of anxiety

                                                                                              7
2nd International Congress of the World Association for Stress Related and Anxiety Disorders
Scientific Program – Thursday, October 3rd

SR 1.012
WASAD Symposium | Imaging of stress-induced brain functional changes
Chair: Martin Walter, Jena, and Andreas J. Fallgatter, Tübingen

           Marie-José van
 15.00                            Imaging stress effects in depression and anxiety
           Tol

 15.20     Martin Walter          Imaging of stress-induced brain functional changes

                                  Neuroimaging results from the Leiden Family Lab study on
           Janna Marie Bas-
 15.40                            Social Anxiety Disorder: a multiplex, multigenerational
           Hoogendam
                                  endophenotype study
                                  Temporal unpredictability increases BNST and Amygdala
 16.00     Niklas Siminski
                                  activity during threat processing

17.00 - 18.00 | Keynote Lecture
HS 0.001
Chair: Elisabeth Binder, Munich

Rachel Yehuda, New York
Intergenerational effects of trauma

18.00 - 20.00 | Welcome Reception

Ground floor

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2nd International Congress of the World Association for Stress Related and Anxiety Disorders
Scientific Program – Friday, October 4th

9.00 - 10.00 | Keynote Lecture
HS 0.001
Chair: Norbert Sachser, Münster

Mathias Schmidt, Munich
Ramping up stress resilience: Genetic and environmental factors

10.30 - 12.00 | Parallel Sessions

HS 0.001
SFB Symposium | How anxiety modulates attention
Chair: Herta Flor, Heidelberg, and Matthias Gamer, Würzburg

                               How to conceptualize, measure, and modify anxiety-related
 10.30     Ernst Koster
                               attentional bias
                               Fear and anxiety in the visual brain - Differential visuocortical
 10.50     Matthias Wieser
                               processing of predictable and unpredictable threat
                               Space, time and anxiety: Survival decisions along defensive
 11.10     Dean Mobbs
                               circuits
                               Fear generalization of implicit conditioned facial features –
 11.30     Kati Roesmann
                               Behavioral and magnetoencephalographic correlates

HS 0.002
WASAD Symposium | Stress resilience and vulnerability
Chair: Annamaria Cattaneo, London, and Marco A. Riva, Milano

           Annamaria           Role of miRNA19 in the mechanisms associated with stress
 10.30
           Cattaneo            vulnerability and stress resilience
                               Molecular signatures of prenatal stress exposure and
 10.50     Marco A. Riva
                               relevance for the susceptibility and resilience to mental illness
                               Stress reactivity in individuals with high vs low interoceptive
 11.10     Hina Ghafoor
                               accuracy
                               Long-term effectiveness of prolonged exposure for adolescents
 11.30     Soraya Seedat       with PTSD using a task-shifted intervention: Randomised
                               controlled trial with supportive counselling as a comparator

                                                                                                   9
2nd International Congress of the World Association for Stress Related and Anxiety Disorders
Scientific Program – Friday, October 4th

SR 1.003
WASAD Symposium | Mapping mechanisms of gene x environment interaction in stress -
                         from endophenotype to disease
Chair: Elisabeth Binder, Munich, and Thora Halldorsdottir, Reykjavik

                              Neurobiology of self-regulation: Longitudinal influence of
           Thora
 10.30                        FKBP5 early life stress on emotional and cognitive
           Halldorsdottir
                              development in childhood
                              A polygenic score of molecular sensitivity to GR-stimulation
 10.50     Immanuel Elbau     maps to stress related changes of the brains hemodynamic
                              response function
           Charlotte          Interactions between FKBP5 variation and environmental
 11.10
           Piechaczek         stressors in adolescent major depression
                              Posttraumatic stress disorder in a war-exposed sample from
           Alma Džubur
 11.30                        Balkan countries: The impact of (epi-) genetic variation on
           Kulenović
                              disease susceptibility and the severity of symptoms

12.15 - 13.15 | Industry Sponsored Session

SR 1.012

13.30 - 14.30 | Keynote Lecture
HS 0.001
Chair: Paul Pauli, Würzburg

Martin Paulus, Tulsa
Computational models of anxiety

14.30 - 17.00 | Poster Session

Open areas on 1st and 2nd floor
List of posters: see pages 19-23
Posters with even numbers are to be presented between 14.30 and 15.45,
posters with odd numbers are to be presented between 15.45 and 17.00.

10
Scientific Program – Friday, October 4th

17.00 - 18.30 | Parallel Sessions

HS 0.001
SFB Symposium | Anxiety Disorders – Prediction, prevention and personalized therapy
Chair: Andreas Papassotiropoulos, Basel, and Katharina Domschke, Freiburg

           Vijaya             Separation anxiety grows up: an overview of separation
 17.00
           Manicavasagar      anxiety in adults

 17.20     Marcel Romanos     Developmental fear generalization

           Katharina
 17.40                        Epigenetics of anxiety
           Domschke
                              Genetic variability of GLRB impact cognitive behavioral
 18.00     Heike Weber
                              therapy response in panic disorder

HS 0.002
WASAD Symposium | Stress and dementia
Chair: Peter Riederer, Würzburg, and Frank Jessen, Cologne

 17.00     Frank Jessen       The role of stress in the development of dementia
                              Early life stress and its programming effects and lasting
 17.20     Paul J. Lucassen
                              consequences
                              Stress and neuroinflammation as possible mediators of acute
 17.40     Ana Babić Perhoč   cognitive dysfunction in a streptozotocin-induced rat model of
                              sporadic Alzheimer’s disease

 18.00     Thomas Polak       Anxiety in old age – data of the Vogel study

                                                                                           11
Scientific Program – Friday, October 4th

SR 1.003
WASAD Symposium | Symposium of the SGAD (Schweizerische Gesellschaft für Angst und
                            Depression)
Chair: Erich Seifritz, Zurich, and Susanne Walitza, Zurich

17.00    Birgit Kleim      Predictors of stress resilience
                           The effect of psychosocial and craving-induced stress on social
17.20    Boris Quednow     cognition and decision-making in cocaine users: a longitudinal
                           approach
                           The relationship between sleep and brain plasticity and its
17.40    Reto Huber
                           relevance for psychiatric disorders
                           Preclinical view on the mechanism of antidepressant activity of
18.00    Hans Kalkmann
                           eicosapentaenoic acid

12
Scientific Program – Saturday, October 5th

9.00 - 10.00 | Keynote Lecture
HS 0.001
Chair: Marcel Romanos, Würzburg

Brenda Penninx, Amsterdam
Towards reducing the public health impact of anxiety disorders

10.30 - 12.00 | Parallel Sessions

HS 0.001
SFB Symposium | Individual differences in fear and anxiety
Chair: Tina Lonsdorf, Hamburg, and Ulrike Lüken, Berlin

           Isaac R. Galatzer- Hacking behavior to understand brain based disorders: the role
 10.30
           Levy               of computation to re-define clinical phenotypes
                               Using individual differences to construct machine learning
 10.50     Kevin Hilbert       based models for single-subject classification and prediction in
                               anxiety and related disorders
                               Theranostic markers for personalized therapy of spider phobia:
 11.10     Elisabeth Leehr     Methods of a bicentric external cross-validation machine
                               learning approach
                               Do individual patterns of attentional exploration predict
 11.30     Mario Reutter
                               differences in fear generalization?

                                                                                              13
Scientific Program – Saturday, October 5th

HS 0.002
WASAD Symposium | Temperament, gene and nutrition in anxiety and related disorders
Chair: Hiroki Ozawa, Nagasaki, and Takeshi Inoue, Tokyo

 10.30     Ken Yonezawa       Relationship between omega-3 fatty acid and mental disorder
           Yoshirou           Gene-based rare variants association test implicates PLA2G4E
 10.50
           Morimoto           as a risk gene for panic disorder
                              Temperaments, child abuse and stressful events in anxiety and
 11.10     Takeshi Inoue
                              related disorders
                              Gene polymorphisms are associated with treatment-resistant
 11.30     Jie Li
                              depression in Han Chinese

SR 1.012
WASAD Symposium | Clinical targets for stress related and anxiety disorders in children and
                         adolescents
Chair: Susanne Walitza, Zurich, and Lizbeth Utens, Amsterdam

                              The link between the genetic risk load, anxiety and stress in
 10.30     Edna Grünblatt
                              individuals at clinical high risk for psychosis
                              Anxiety in children with somatic conditions: outcome of CBT
 10.50     Lizbeth Utens      and EMDR for the clinical targets IBD and congenital heart
                              disease
                              Potential DNA methylation and miRNA markers for
 11.10     Ulrike Schmidt
                              posttraumatic stress disorder (PTSD)
           Madlena
 11.30                        Psychological risk factors of gifted adolescents
           Arakelyan

12.15 - 13.15 | Industry Sponsored Session

HS 0.002

14
Scientific Program – Saturday, October 5th

13.30 - 14.30 | Keynote Lecture
HS 0.001
Chair: Christian Büchel, Hamburg

Thomas Kash, Chapel Hill
The role of the extended amygdala in alcohol-drinking driven alterations in threat response

15.00 - 16.30 | Parallel Sessions

HS 0.001
SFB Symposium | Neural dynamics of aversive learning
Chair: Marta Andreatta, Würzburg, and Jan Haaker, Hamburg

 15.00     Andreas Olsson      Social learning and decision making under threat
                               Dissociable influences of anxiety on pain and arousal during
 15.20     Lauren Atlas
                               aversive reversal learning
                               Influencing and modulating factors of aggression and
 15.40     Ute Habel
                               impulsivity

 16.00     Christian Büchel    Neural mechanisms of fear generalization

HS 0.002
WASAD Symposium | (Maternal) Stress and its consequences: from animals to humans
Chair: Birgit Derntl, Tübingen, and Andreas J. Fallgatter, Tübingen

 15.00     Liisa Galea         Stress effects in postpartal depression
                               Stress and its consequences on cognition and emotion in
 15.20     Birgit Derntl
                               women and men
                               Psychological outcomes after pediatric hospitalization: the role
 15.40     Maya Meentken
                               of trauma type
                               Truth lies in the hair: Prenatal hair steroids predict postpartum
 16.00     Thorsten Mikoteit
                               depression

                                                                                               15
Scientific Program – Saturday, October 5th

SR 1.012
WASAD Symposium | Anxiety, depression and cognition in brain and heart
Chair: Jürgen Deckert, Würzburg, and Stefan Frantz, Würzburg

                             Investigating the brain-heart connection: the Depression
15.00     Andreas Menke
                             Associated Cardiac Failure (DACFAIL) Study
                             A web-based intervention for improving psychosocial distress
15.20     Stefan M. Schulz   in heart failure patients with an implantable cardioverter
                             defibrillator
          Sarah Kittel-      Anxiety, depression and heart function – The genetic
15.40
          Schneider          connection

16.00     Anna Frey          Cognition matters in patients with chronic heart failure

17.00 - 18.30 | Parallel Sessions

HS 0.001
WASAD Symposium | Telemedicine and mobile assessment in stress related disorders
Chair: Tobias J. Renner, Tübingen, and Gudmundur Skarphedinsson, Reykjavik

17.00     Karsten Hollmann E-health interventions in pediatric OCD
          Gudmundur          Developing and implementing iCBT for pediatric obsessive-
17.20
          Skarphedinsson     compulsive disorder in Iceland
                             An online based stress management intervention for patients
17.40     Sonja Kleih
                             with Parkinson’s disease
                             Clinical, behavioral and magnetoencephalographic correlates
18.00     Kati Roesmann      of fear generalization before and after virtual reality exposure
                             therapy in spider phobia

16
Scientific Program – Saturday, October 5th

HS 0.002
WASAD Symposium | Anxiety: genetics, social interactions and therapy
Chair: Grit Hein, Würzburg, and Manuel Mattheisen, Würzburg

           Manuel              OCD genetics: updates from the Danish OCD and Tourette’s
 17.00
           Mattheisen          study and the Psychiatric Genomics Consortium

 17.20     Angelika Erhardt    Genetics and epigenetics of panic disorder

 17.40     Grit Hein           Social buffering of anxiety

                               Expectancy violation as mechanism of change in exposure-
 18.00     André Pittig
                               based cognitive-behavioural therapy

SR 1.012
WASAD Symposium | Adult ADHD and stress: cause or consequence?
Chair: Christian Jacob, Esslingen, and Gara Arteaga Henríquez, Barcelona

           Gara Arteaga
 17.00                         Cortisol awakening response and ADHD
           Henríquez

 17.20     Corina Greven       ADHD and stress-reducing psychotherapy

 17.40     Francisco Esteves   Attention, eating disorders and body dissatisfaction

           Sarah
 18.00                         Chronic stress and quality of life in adult ADHD
           Kittel-Schneider

18.45 - 19.00 | Closing Ceremony

HS 0.002
Awards Ceremony for poster awards
Closing remarks
Peter Riederer, Germany

                                                                                      17
Speakers

Keynote speakers                    Kay Jüngling, Münster
Thomas Kash, Chapel Hill            Hans Kalkmann, Basel
Martin Paulus, Tulsa                Sarah Kittel-Schneider, Würzburg
Brenda Penninx, Amsterdam           Sonja Kleih, Würzburg
Mathias Schmidt, Munich             Birgit Kleim, Zurich
Rachel Yehuda, New York             Ernst Koster, Ghent
                                    Elisabeth Leehr, Münster
                                    Jie Li, Tianjin
Speakers in plenary symposia        Paul J. Lucassen, Amsterdam
(listed in alphabetical order)      Vijaya Manicavasagar, Sydney
Madlena Arakelyan, Yerevan          Manuel Mattheisen, Würzburg
Lauren Atlas, Bethesda              Maya Meentken, Rotterdam
Ana Babić Perhoč, Zagreb            Andreas Menke, Würzburg
Janna Marie Bas-Hoogendam, Leiden   Thorsten Mikoteit, Solothurn
Christian Büchel, Hamburg           Dean Mobbs, Pasadena
Annamaria Cattaneo, London          Yoshirou Morimoto, Nagasaki
Birgit Derntl, Tübingen             Andreas Olsson, Stockholm
Julia Diemer, Wasserburg            Charlotte Piechaczek, Munich
Katharina Domschke, Freiburg        Andre Pittig, Würzburg
Alma Džubur Kulenović, Sarajevo     Thomas Polak, Würzburg
Immanuel Elbau, Munich              Boris Quednow, Zurich
Angelika Erhardt, Munich            Gal Richter-Levin, Haifa
Francisco Esteves, Östersund        Mario Reutter, Würzburg
Anna Frey, Würzburg                 Marco Riva, Milano
M. S. Fustiñana, Basel              Marcel Romanos, Würzburg
Liisa Galea, Vancouver              Kati Roesmann, Münster
Isaac R. Galatzer-Levy, New York    Miriam Schiele, Freiburg
Hina Ghafoor, Würzburg              Ulrike Schmidt, Göttingen
Corina Greven, Nijmegen             Stefan M. Schulz, Würzburg
Edna Grünblatt, Zurich              Soraya Seedat, Stellenbosch
Ute Habel, Aachen                   Niklas Siminski, Würzburg
Thora Halldorsdottir, Reykjavik     Gudmundur Skarphedinsson, Reykjavik
Grit Hein, Würzburg                 Andreas Ströhle, Berlin
Gara Arteaga Henríquez, Barcelona   Marie-José van Tol, Utrecht
Martin Hermann, Würzburg            Philip Tovote, Würzburg
Kevin Hilbert, Berlin               Lizbeth Utens, Amsterdam
Karsten Hollmann, Tübingen          Martin Walter, Jena
Reto Huber, Zurich                  Heike Weber, Würzburg
Takeshi Inoue, Tokyo                Matthias Wieser, Rotterdam
Frank Jessen, Cologne               Ken Yonezawa, Nagasaki

18
Posters

Poster Session | Friday, October 4th, 14.30 - 17.00

Posters with even numbers are to be presented between 14.30 and 15.45,
posters with odd numbers are to be presented between 15.45 and 17.00.

 Group A
                                      Serotonergic system of the anterodorsal BNST is involved
 1     Hessel, Margarita   Münster
                                      in phasic and sustained fear in freely behaving mice
       Krakenberg,                    Effect of serotonin transporter deficiency on the cognitive
 2                         Münster
       Viktoria                       judgment bias of mice
                                      Towards highly specific genetic manipulation of the mouse
       Remmers,                       cannabinoid CB1 receptor using CRISPR/Cas9: cell-type
 3                         Mainz
       Floortje                       selective and region-specific CB1 knockout in the adult
                                      brain and generation of a CB1 point-mutation mouse line
 4     Kästner, Niklas     Münster    Brain serotonin deficiency affects female aggression
                                      Impact of Brain-Derived Neurotrophic Factor on synaptic
 5     Fiedler, Dominik    Münster    transmission and plasticity in the oval nucleus of Bed
                                      Nucleus of the Stria Terminalis
                                      OCD and neurodegeneration in SPRED2-deficient mice is
 6     Hepbasli, Denis     Würzburg   associated with brain ventricle enlargement and ultrasonic
                                      vocalization changes
                                      Local deletion of Y2 receptors in BNSTav mediates
 7     Jamil, Sara         Münster
                                      extinction and return of remote fear memory
                                      Altered expression of genes related to the vasopressin and
       Hamann,
 8                         Würzburg   oxytocin brain systems: A study with 5-HTT deficient mice
       Catharina
                                      after experiencing prenatal stress
                                      Stress-induced epigenetic programming in serotonin
 9     Zöller, Johanna     Würzburg   transporter deficient mice: Epigenetic editing – a strategy
                                      to cope with anxiety
                                      A human relevant polymorphism in the Neuropeptide-S
 10    Goedecke, Lena      Münster    receptor (NPSR1 I107N) alters receptor signaling and fear-
                                      related behavior in mice
       Cortes Cortes,                 Neuroanatomical tracing of glutamatergic brainstem
 11                        Würzburg
       Orlando Jose                   circuits for behavioral and autonomic defense responses
       Signoret-Genest,               Brainstem circuits for cardiac interoception and control of
 12                        Würzburg
       Jérémy                         defensive states
                                      Impact of the human neuropeptide-S receptor
 13    Jüngling, Kay       Münster
                                      polymorphism (I107N) on fear and anxiety in mice

                                                                                               19
Posters

 Group B
                         Brno, Czech Life-long effects of extreme stress on brain structures – a
 14   Fňašková, Monika
                         Republic    holocaust survivor MRI study
                                       Temporal dynamics of threat processing: Modulation of
 15   Sperl, Matthias    Marburg       event-related potential components during a sequential-
                                       set fear acquisition paradigm
                                       Anxiety sensitivity as a modulator of fear generalization in
 16   Vietz, Melanie     Würzburg
                                       healthy adults
      Berking, Ann-
 17                      Würzburg      The role of DNA methyltransferases in anxiety disorders
      Cathrine
                                       The TGFB-Inducible Early Growth Response Protein 2
 18   Kollert, Leonie    Würzburg      (TIEG2) gene as a new candidate in the etiology of panic
                                       disorder?
                                       Deep learning can increase the reliability, objectivity,
 19   Segebarth, Dennis Würzburg
                                       reproducibility and transparency in image data analysis
                                       Reward prediction error signaling during reinforcement
 20   Becker, Michael    Münster       learning in social anxiety disorder is altered by social
                                       observation
      Nieratschker,                    Investigation of MORC1 DNA methylation as biomarker of
 21                      Tübingen
      Vanessa                          early life stress and depressive symptoms
                                       Fear generalization in children and adolescents: a cross-
 22   Slyschak, Anna     Würzburg
                                       sectional study across ages
                                       Investigating attentional mechanisms during                   the
 23   Stegmann, Yannik   Würzburg
                                       interaction of phasic fear and sustained anxiety
      Klinke,                          Distal stress     induction     facilitates    fear        memory
 24                      Würzburg
      Christopher M.                   consolidation
                                       Nx4 effect on stress-induced changes in EEG frequency
 25   Krylova, Marina    Tübingen
                                       powers
                                       Magnetoencephalographic           correlates          of      fear
 26   Wessing, Ida       Münster
                                       generalization in adolescence
                                       Early negative attentional bias in persons with high
 27   Riepl, Korbinian   Würzburg
                                       depressive symptoms during a facial oddball task
      Muehlhan,                        Dose-dependent effects of cortisol on functional large-
 28                      Hamburg
      Markus                           scale connectivity of the visual cortex
                                       Association between rs734194 genetic variant of nerve
                         Yerevan,
 29   Avetyan, Diana                   growth factor receptor (NGFR) and peripheral telomere
                         Armenia
                                       length with posttraumatic stress disorder
                                       Freezing of gaze supports action preparation under threat
 30   Rösler, Lara       Würzburg
                                       imminence

20
Posters

                                        Adenosine A1 receptor availability in healthy human
31   Hohoff, Christa      Münster       brains: Modulation by interacting adenosinergic gene
                                        variants and sleep habit in anxiety-related brain regions
32   Weber, Heike         Würzburg      Allelic variation in PPID predisposes to anxiety disorders
     Ridderbusch,                       Stability and reliability of the delayed extinction fMRI-
33                        Marburg
     Isabelle Caroline                  paradigm of the multicentric trial PROTECT-AD
     Leimeister,
34                        Würzburg      Subsequent memory effects in threat and safety learning
     Franziska
                                        Modulation of pain by social stress - the role of positive and
35   Schneider, Sarah     Würzburg
                                        negative feedback
                                        Reducing Generalization of Conditioned Fear: comparison
36   Herzog, Katharina    Würzburg      of a fear-specific discrimination training with fear-
                                        unrelated control tasks
     Merscher, Alma-                    Freezing of gaze in conditions that require distributed
37                        Würzburg
     Sophia                             attention
38   Zillig, Anna-Lena    Würzburg      The influence of learned safety on pain perception
                                        Temporal dynamics of costly avoidance in newly acquired
39   Boschet, Juliane     Würzburg
                                        fears
                                        Context conditioning and extinction in virtual reality:
40   Winkler, Markus      Würzburg
                                        effects on self-report in anxiety patients
                                        Habitual and goal-directed           avoidance     behavior:
41   Glück, Valentina     Marburg
                                        associations with trait anxiety
                          Zurich,       Associations between the genetic burden, anxiety and
42   Smigielski, Lukasz
                          Switzerland   stress in the at-risk state for psychosis
                                        Sleep quality and salivary biomarkers: A pilot study
                                        connecting the cortisol awakening response and the dim
43   Dubberke, Anne       Trier
                                        light melatonin onset with an overnight polygraphy
                                        assessment

                                                                                                     21
Posters

 Group C
                                        Single or multiple dose applications of Silexan do not
 44   Klement, Stephan    Karlsruhe     impair fitness to drive – results from a placebo-controlled
                                        crossover trial
                                        Repeated stress leads to enhanced cortisol stress response
 45   Asbrand, Julia      Freiburg      in child social anxiety disorder but this effect can be
                                        prevented with CBT
      Kreifelts,                        The neural correlates of face-voice-integration in social
 46                       Tübingen
      Benjamin                          anxiety disorder
                                        Associations between resting state connectivity, symptom
 47   Seeger, Fabian      Würzburg      severity and within-session extinction in the treatment of
                                        spider phobia
      Schwarzmeier,                     Brain-morphometric      predictors    of    within-session
 48                       Würzburg
      Hanna                             extinction during behavioral exposure in spider phobia
                                        Work tandems of psychiatry and anxiety self-help: Can
 49   Goede, Wolfgang     Munich        research and society benefit from the collaboration of
                                        academic experts and experience experts?
                          Sarajevo,
                          Bosnia and Combination of aripiprazole and clozapine in first episode
 50   Hasanagic, Senad
                          Herze-     of psychosis and metabolic syndrome: report of five cases
                          govina
      Baumgartner,        Zurich,       Inter-informant agreement of the Children’s Depression
 51
      Noemi               Switzerland   Rating Scale Revised in depressed children and adolescents
                                        Excitatory transcranial direct current stimulation of the
      Junghöfer,
 52                       Münster       anterior ventromedial prefrontal cortex reveals add-on
      Markus
                                        effects for the therapy of Major Depressive Disorder (MDD)
                                        The comparative analysis of cognitive function and
                          Tianjin,
 53   Li, Pan                           neuropsychiatric behavior between Alzheimer's disease
                          China
                                        and frontotemporal dementia patients
      Scherf-Clavel,                    How smoking cigarettes affects the serum concentrations
 54                       Würzburg
      Maike                             of escitalopram
      Scherf-Clavel,                    Baseline HPA axis activity predict improvement in HPA axis
 55                       Würzburg
      Maike                             function during antidepressant treatment
                          Paris,
 56   Lellouch, Laurent                 Vocal markers of pre-operative anxiety: a pilot study
                          France
                          Zurich,
      Häberling,                        Anxious depression as a clinically relevant subtype of
 57                       Switzer-
      Isabelle                          pediatric major depressive disorder
                          land
 58   Herrmann, Martin Würzburg         Non-invasive brain stimulation augments fear extinction
                                        Association of pain relief for chronic musculoskeletal pain
                                        after interdisciplinary multimodal pain treatment (IMPT)
 59   Breisinger, Sarah   Würzburg
                                        with serum concentrations of antidepressant drugs in a
                                        real-life analysis
                          Tianjin,      The prevalence, risk factors of burnout in Chinese
 60   Li, Shen
                          China         preschool teachers

22
Posters

                                         Heart rate variability associated with suicidality in
 61     Sauter, Amelie       Würzburg
                                         depressed patients
                             Tianjin,    Suicide rates changing in China and suicide prevention in
 62     Li, Jie
                             China       Tianjin

 63
                                         Genetic variability of GLRB impact cognitive
        Weber, Heike         Würzburg
                                         behavioral therapy response in panic disorder
                                         Transcranial ultrasound neuromodulation as a new
                                         potential intervention for affective disorders - Recent
 64     Ziebell, Philipp     Würzburg
                                         findings and ideas for the future from a differential
                                         psychology perspective
        Pfaffinger,                      Development and test of a new scale for the measurement
 65                          Munich
        Katharina F.                     of digital anxiety
 66     Hellmuth, Anna       Würzburg    SGK1 signaling predict response in major depression
                             Jakarta,
 67     Andri, Andri                     Somatic Symptoms in Depression: Indonesian Perspective
                             Indonesia
                                         Microdeletion syndrome 22q11.2 – Clinical and Molecular
 68     Hock, Anja           Würzburg
                                         Characterization of a High-Risk Cohort
                                         Treatment overview of mentally ill patients at Bugando
                             Mwanza,
 69     Wambura, Matiko                  Medical Centre in Mwanza, Tanzania with a focus on PTSD,
                             Tanzania
                                         Depression and Anxiety
                             Stellen-
                             bosch,      Childhood trauma and hippocampal subfield volumes in
 70     du Plessis, Stéfan
                             South       first-episode schizophrenia and healthy controls
                             Africa

Three poster award winners – one from each group, in order to represent the entire spectrum
of topics – will be selected by the award committee:
R. Blum, Würzburg; A. Fallgatter, Tübingen; J. Haaker, Hamburg; M. Herrmann, Würzburg;
C. Jacob, Esslingen; S. Kittel-Schneider, Würzburg; T. Lonsdorf, Hamburg; U. Lüken, Berlin;
A. Ströhle, Berlin

                                                                                                 23
General Information

Registration and Organizer of the Industrial Exhibition & Sponsoring
INTERPLAN
Congress, Meeting & Event Management AG
Project Management: Jasmin Greger
Landsberger Strasse 155
80687 Munich, Germany
Phone +49 (0) 89 54 82 34 62
Fax +49 (0) 89 54 82 34 62
wasad@interplan.de

Opening Hours of the registration counter
3 October 2019:        10.00 – 18.30
4 October 2019:        08.00 – 19.00
5 October 2019:        08.00 – 19.00
The registration desk is open for registration and assistance during the above mentioned
opening hours. Onsite registration is possible at the registration counter. Registration fees can
be paid in cash or via credit card. Registration for single days is not possible.

Registration Fees
Regular Registration Fee:                    € 390
Student Fee*:                                € 70
SFB Members/GAF Members**:                   € 180

*Only valid for full time students who have not finished their studies yet before the congress starts. A valid/current
student ID copy or letter from advisor is required.
**Validity of membership will be checked

Name Badge
Please wear your name badge for the entire duration of the congress. It serves as your entrance
ticket.

Opening Hours of the industrial exhibition
3 October 2019:     13.30 – 18.00
4 October 2019:     08.30 – 18.30
5 October 2019:     08.30 – 17.00

24
General Information

Catering:
Coffee, cold drinks, snacks, and a light lunch are available in the catering area on the 2nd floor.

Changes of schedule at short notice:
In case of necessary changes of schedule at short notice (cancellation or time changes of single
talks or sessions, change of speaker), the registration fee cannot be refunded.

WiFi:
Free WiFi is available at the congress site either via “eduroam” (if set up by your home
university) or via “BayernWLAN” (free WIFI, no password necessary).

Data Protection
Interplan handles all personal data according to the laws of the EU-Data Protection Regulation
(EU-GDPR) and the Federal Data Protection Act (BDSG New). For your booking within the above
mentioned congress the collecting, saving and processing of your personal data is imperative.
This is done solely as a means of the organization and completion of the event. We will collect
your data on behalf of the World Association for Stress Related and Anxiety Disorders e.V.
(WASAD), Schwanenhof 4, 97070 Würzburg, Germany.
Your data will only be passed onto a third party who is directly involved with the running of the
Congress and when the organizational procedure makes this necessary (operator, hotel). The
registration to this congress is not possible if we do not get this.

For a complete overview of the applicable privacy policy, see the following Link:
https://www.interplan.de/en/data-protection.php#datasec

                                                                                                 25
General Information

Congress Venue:
Zentrales Hörsaal- und Seminargebäude Z6, Am Hubland, 97074 Würzburg

                        Map data © OpenStreetMap contributors

Bus from Würzburg Hauptbahnhof (main station):
           Line 114 – direction “Hubland” – to stop „Hubland/Mensa“
           Line 214 – direction “FHWS” – to stop „Hubland/Mensa “

Bus from Sanderring (stop „Sanderglacisstraße“):
            Line 10 – direction “Sprachenzentrum/Campus Nord” – to stop „Hubland/Mensa“

Taxi dispatch Würzburg:
             Phone +49 931 19410

26
About WASAD

Society Profile
The World Association for Stress-related and Anxiety Disorders, WASAD, is an independent non-
profit organization founded in 2016 by leaders of clinical and translational science.

Board:
President:           Prof. Dr. P. Riederer, Würzburg
Vice-President:      Prof. Dr. A. Fallgatter, Tübingen
Secretary:           Prof. Dr. T. Renner, Tübingen
Treasurer:           Prof. Dr. C. Jacob, Esslingen

WASAD has set itself the goal:
   To promote basic research on stress-related and anxiety disorders
   To ensure effective and safe drug treatment and prevention strategies for these mental
     illnesses
   To make the interdisciplinary scientific findings suitable for clinical and psychological
     institutions and their representatives
   To offer the right framework for clinicians and practicing physicians, psychotherapists,
     physicians and psychotherapists in training, students and health care professionals in
     order to exchange knowledge and experiences in the fields of clinical and basic research,
     stress, stress-related and anxiety disorders
   To make recommendations to current therapy-relevant topics
   To promote international contacts in this field

                                                                                           27
Sponsors

The support of the following sponsors and exhibitors is gratefully acknowledged:

28
Sponsors

      29
Sponsors

30
Industry Sponsored Sessions

Friday, 12.15 - 13.15 | Industry Sponsored Session

SR 1.012
Heel Symposium | Imaging All the data – what can and what can’t we get from
                      pharmacological and other interventional brain imaging studies on
                      stress and anxiety?
Chair: Martin Walter, Jena

          Rupert              Chances and limitation for Multimodal MRI and PET imaging
 12.15
          Lanzenberger        studies on pharmacological mechanisms
                              Resting state and task fMRI insights on mechanisms of
 12.35    Martin Walter
                              mediation and complex therapeutics
                              Limitations and lessons learned from brain imaging studies –
 12.55    Steven Williams
                              implications for studies of stress and anxiety

Saturday, 12.15 - 13.15 | Industry Sponsored Session

HS 0.002
Janssen Symposium | Depression and Suicidality - from Neurobiology to clinical practice
Chair: Martin Walter, Jena, and Claus Normann, Freiburg

 12.15    Claus Normann       Depression

 12.45    Martin Walter       Suicidality

                                                                                          31
Sponsors

Industrial Exhibition

Exhibitor                                     Booth Number
Akademische Buchhandlung Knodt                      5
daacro-Contract Research & Saliva Lab Trier         2
Heel GmbH                                           6
Janssen                                             4
neuraxpharm Arzneimittel GmbH                       3
Recordati Pharma GmbH, Ulm                          1
Schwabe Pharma Deutschland                          7

32
Sponsors

Disclosure
As organizer of the industrial exhibition, Interplan AG is obliged to disclose all sums received by
sponsors and exhibitors in order to comply with the regulations of the Bayerische
Landesärztekammer (BLÄK). For the industry partners mentioned below, we are herewith
informing about their overall support within the framework of the WASAD Congress 2019*.

Company                                              Total Amount
daacro-Contract Research & Saliva Lab Trier          1.000,00 €
Heel GmbH                                            16.000,00 €
Janssen                                              15.000,00 €
neuraxpharm Arzneimittel GmbH                        1.500,00 €
Recordati Pharma GmbH, Ulm                           1.000,00 €
Schwabe Pharma Deutschland                           1.000,00 €

*at the time of printing

Furthermore, WASAD wishes to acknowledge the support of
XXXLutz KG
Springer Nature
VENT e.V.
Dr. med. Edda Neele Stiftung

                                                                                                33
Sponsors

34
For your notes

            35
www.wasad2019.org
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