Air Pollution and Health in Developing Asia - China Specific Impacts from the Global Burden of Disease

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Air Pollution and Health in Developing Asia - China Specific Impacts from the Global Burden of Disease
Air Pollution and Health in Developing Asia
China Specific Impacts from the Global Burden of
                    Disease
      A dialogue on air science and policies in China and Hong Kong

                        Robert O’Keefe
             Vice President, Health Effects Institute
                     Chair Clean Air Asia
                          Hong Kong
Air Pollution and Health in Developing Asia - China Specific Impacts from the Global Burden of Disease
Public Health Impact can be a major
             driver of decisions
• It demonstrates that air pollution is an important
  factor affecting people, nations
  • Provides health-based rationale for air quality and
    source standards worldwide
  • Provides the health basis for assessing costs & benefits
  • Standards, in turn, drive technology decisions with air
    and climate implications
     • Cleaner vehicles & alternate transport
     • Less coal-fired electricity, efficiency, alternate fuels
Air Pollution and Health in Developing Asia - China Specific Impacts from the Global Burden of Disease
Most Chinese Cities Substantially Exceed WHO,
                                              Chinese Air Quality Guidelines
          160
                                                   2009 Annual Mean PM10 Levels in Chinese Cities
          140

                                                       China Standard: 100µg/m3
          120
Annual Mean PM10 Levels (µg/m3 )

          100

                     80

                     60
                                         WHO Guideline: 20 µg/m3

                     40

                     20

                                   0

                                                                                                    Source: WHO 2011
Air Pollution and Health in Developing Asia - China Specific Impacts from the Global Burden of Disease
Estim ated population-w eighted am bient air pollution
levels - PM 2.5 -increased w orldw ide and in China 1990-
                           2010
                                  50% increase in
1990 → 2010:                      population-weighted
10% increase in global
population-weighted PM2.5
                                  PM2.5
Air Pollution and Health in Developing Asia - China Specific Impacts from the Global Burden of Disease
The Global Burden of Disease (GBD)

• A systematic scientific effort to quantify the magnitude of health
  loss from disease and injuries in 187 countries around the world
  from 1990 to 2010
   • E.g. cardiovascular disease, respiratory disease, HIV-AIDS, cancer road
     traffic injuries and
• Risks associated with conditions linked with those diseases
   • E.g. smoking, diet, high blood pressure, air pollution, overweight
   • Measured as “Disability Adjusted Life Years (DALYs) and Mortality”
• Last completed with WHO for Year 2000
• Newest version, funded by Gates Foundation, was published in
  December, 2012
   • HEI leadership for outdoor air pollution analysis
Air Pollution and Health in Developing Asia - China Specific Impacts from the Global Burden of Disease
Published in
Special Triple
 Issue of The
    Lancet
December 2012
Air Pollution and Health in Developing Asia - China Specific Impacts from the Global Burden of Disease
GBD 2010 Team
    488 authors from 303 institutions in 50 countries.

7
Air Pollution and Health in Developing Asia - China Specific Impacts from the Global Burden of Disease
The Evidence:
What are the GBD estimates based on?
Air Pollution and Health in Developing Asia - China Specific Impacts from the Global Burden of Disease
Particulate Matter (PM)
• High levels of PM (> 500 µg/m3)
  known to cause premature death
   • e.g. London 1952
• Thousands of studies in US, Europe,
  elsewhere have found association of
  PM with mortality at much lower
  levels (
Air Pollution and Health in Developing Asia - China Specific Impacts from the Global Burden of Disease
Chinese PM10 Evidence from the
                 PAPA Multi-City, Coordinated Studies
                    HEI Research Report 154, November 2010

•Conducted in partnership with principal
investigators Dr. Kan Haidong (Fudan),;
Dr. CM Wong (University of Hong
Kong), among others

•Consistent small increase in risk with
daily increase in PM10

•Communication 13, available at
www.healtheffects.org/publications

                                           Excess risk (%) of mortality for a 10mg/m3 increase in
                                           average concentration of pollutants (lag 0-1 days)
Asia in a Global Context
                 (PM10 and Daily Mortality)
The effects of pollution are more similar than different …
     …and global science can be broadly relevant
Asia in a Global Context:
Recent China results on long term effects of air pollution are
 consistent with the results of the Global Burden of Disease

                                                        GBD risk
                                                        functions
                                                        China results:
                                                        Cao et al.
                                                        2011
The GBD 2010
Results for Air
  Pollution
Previous Global Burden of Disease in
                           2000
                  Mortality attributable to leading risk factors
                High blood pressure
                            Tobacco
                    High cholesterol
                        Underweight
                          Unsafe sex
       Low fruit and vegetable intake
              Overweight and obesity
                   Physical inactivity
                              Alcohol
Unsafe water, sanitation, and hygiene
                                                                         High-mortality developing
       Indoor smoke from solid fuels
                      Iron deficiency
                                                                         Lower-mortality developing

                  Urban air pollution                                    Developed
                      Zinc deficiency
                Vitamin A deficiency
                                                                  Outdoor Air Pollution
 Contaminated health care injections
   Occupational airborne particulates
                                                                      ranked 13th
  Occupational risk factors for injury
                      Lead exposure
                          Illicit drugs

                                          0   1000       2000    3000    4000        5000      6000   7000   8000

     Ezzati et al. 2002; WHO 2002                    Mortality in thousands (Total 55.86 million)
2010: Ambient PM2.5 now among the leading global risks
       for mortality and lost years of healthy life
      (Lim et al 2012, and http://viz.healthmetricsandevaluation.org/gbd-compare/)

                                                                  Contributes
                                                                  to 3.2 million
                                                                  premature
                                                                  deaths
                                                                  worldwide
Dramatic Demographic Shifts: People Living Much
             Longer Worldwide
But increased susceptibility to “diseases of aging”
(heart disease, stroke, COPD, lower respiratory
infection, lung Cancer…diseases most associated
with air pollution

                                     East Asia

                        South Asia
New, More Extensive Global Estimates Based on
        Measurements, Remote Sensing
                    (Brauer, et al, 2011)

Combined estimates from satellites (AOD), chemical
transport models and ground-level measurements

                     -Highest regional averages in East /South
                     Asia
                     -Many breathe concentrations much higher
                     than regional average
                     -89% population in areas exceeding WHO PM
Top 20 Mortality Risk Factors in China for 2010
      Ambient PM2.5 is 4th leading factor
  (Lim et al 2012, and http://viz.healthmetricsandevaluation.org/gbd-compare/)

                                                                   Ambient PM2.5
                                                                   contributed to
                                                                   estimated 1,2
                                                                   million
                                                                   premature
                                                                   deaths in 2010
Public Health Impact of Air Pollution
       is well-documented and substantial
• GBD 2010 documents that air pollution is a very important factor
  affecting global public health
• High levels of outdoor air pollution are responsible for over 3.2
  million premature deaths annually and 76 million years of healthy
  life years lost around the world
• Developing Asia, including India and China bears over 2/3 of the
  world wide global health burden in this key area
• 60 years of western health studies and an increasing base of high
  quality Asian health studies provide confidence in this assessment

• Health, economic and ecological reasons to take action
• Actions typically highly cost effective
Thank You!
   Robert O’Keefe
rokeefe@healtheffects.org
Positive Steps in China, to Reduce Air Pollution
            …by government that can benefit air pollution and climate
Significant new national monitoring program for PM2.5 and O3 underway
    o China-Wide by 2016
    o Real time transparent reporting will maintain public focus
2012 --Recent pollution limits for PM and Ozone
    o Standards are comparable to WHO interim targets (IT); Grade II PM2.5, PM10
       and O3
2013 National Action Plan;
      -Bans new coal plants around Beijing, Shanghai, key regions
      -Begin shift from coal to gas, renewables, nuclear (2017 reduction to 65% total
         coal in energy consumption) …though recent projections show increases in
         coal mining, due to growth in overall energy use
-Target 10% reduction in urban fine particle pollution by 2017, additional
         reductions in 3 major regions

-2013 State Council Clean Fuels Roadmap for China: fuel quality (10 PPM
    Sulfur), aggressive scrappage, other transport measures

    Much more work needed….compliance and follow through
    critical …As are the recommendations of RAQM
Air Quality, PM, and Cancer
               • New review of all air pollution
                 and cancer
               • Follows reviews of many
                 components: PAHs, benzene,
                 butadiene, diesel
               • Called Air Pollution, and PM,
                 known human carcinogens
                 (Group 1) based on:
                   • US (ACS) and Europe
                     (ESCAPE) long term cohorts
                     that found associations with
                     lung cancer
               • According to GBD,
                 approximately 220,000 lung
                 cancer deaths attributable to air
                 pollution worldwide

              22
K ey Features of the GBD AQ im pact estim ates for China
                    (Yang GH et al. The Lancet 2013)

• Includes the entire population
  both urban and rural
   • Prior studies had only estimated
     urban
• Estimates PM2.5 exposure
  using satellites, air quality
  models, and data from >100
  Chinese monitors
• Risk estimates based on
  systematic review and
  synthesis of all latest
  epidemiologic studies
   • These are consistent with the
     results of newest Chinese studies
• Methods and results published
  in peer-reviewed journals - all
  data are publically available
Estimated 2010 levels of PM2.5 in China
Household solid fuel emissions also contribute
           to Ambient Air Pollution

• Global: Household emissions contribute ~15% (4 µg/m3) of ambient PM2.5
• China: Household emissions contribute ~ 15% (7 µg/m3) of PM2.5
• India: Household emissions contribute ~25-30% (10µg/m3) of PM2.5

•The fifth leading risk factor for mortality in China in 2010
~ 1 million premature deaths
IARC Meeting on Diesel
                               June 5 – 12, 2012
• Noted substantial (>98%) improvements in new technology diesel in US, Europe
• Based review on animal and human exposures to old (and much older) diesel
• Concluded that:
    • Animal studies provided sufficient evidence of link between diesel and cancer
    • Human studies (with DEMS added) provided sufficient evidence of link
    • Mechanistic studies provided strong evidence of plausible mechanisms by
      which diesel could cause cancer in humans

Classified diesel exhaust
as a “known” human
carcinogen
Summary
• The Public health impact of air pollution key to informing, driving policy

• GBD, the new global standard for credible health impact assessment,
  finds the greatest burden in developing Asia, with over 630,000 premature
  deaths and 74 million health years of life lost 2010
• Vehicles are not the only source of concern for air pollution, but high
  urban exposures and proximity to roadways of dense populations in
  India’s cities makes it a special concern
• Emissions from older diesel engines, with significant PM impacts, and
  new IARC designation as Known Human Carcinogen is an important
  source to reduce
• HEI ACES continues to document that new technology diesel, with low
  sulfur fuel and particle filters yields dramatic emission reductions and
  negligible health effects, is an important way forward
In China: Health Concerns Driving New PM2.5 and Ozone
   Air Quality Standards (2012 - 2016), New Transparency

Extreme pollution episodes result in citizen unrest, international
embarrassment, expat flight, Chinese official press GBD coverage:
                    Air pollution sped death of 1.2 million in
 China
                Global
Together, drive flurry of Times
                          action by|Chinese
                                     2013-4-2   0:53:0
                                            Government

Recent directions
•2012 --New pollution limit and monitoring requirements for PM and Ozone
    o Standards are comparable to WHO interim targets (IT); Grade II PM2.5, PM10 and
       O3

Significant new monitoring phased in over next four years
    o National monitoring program for PM2.5 and O3 underway
    o China-Wide by 2016
    o Real time transparent reporting will maintain public focus

An increasingly affluent middle-class can afford to care about pollution
Am bient Air Pollution Ex pert Group
H Ross Anderson (Co-Chair)       SGHM S U London
Markus Amann                     I I ASA/ Vienna
Michelle Bell                    Yale University
Michael Brauer                   U British Colum bia
Bert Brunekreef                  U Utrecht
Richard Burnett                  Health Canada
Aaron Cohen (Co-Chair)           Health Effects I nstitute
Frank Dentener                   EC-JR C
Majid Ezzati                     Harvard University
Bryan Hubbell                    USEPA
Kan Haidong                      Fudan University
Michal Krzyzanowski              W HO/ Euro-Bonn
Francine Laden                   Harvard University
Stephanie London                 NI EHS
Randall Martin                   Dalhousie University
Sumi Mehta                       UN Fnd Clean Stoves Program
Bart Ostro                       California EPA
Kiran Dev Pandey                 W orld Bank
Arden Pope                       Brigham Young U
Beate Ritz                       UCLA
Isabelle Romieu                  I AR C
Amir Sapkota                     U M aryland
Kirk Smith                       UC Berkeley
George Thurston                  New York University
Rita van Dingenen                EC –JR C
Aaron van Donkelaar              Dalhousie University
Asia PM 2.5 Source Apportionment: Vehicles ~20% - 35%

                               Source: Chowdhury, HEI
Coal consumption key contributor to
regional background
Household and Ambient Air Pollution:
           India and China face a double burden

• Household air pollution (HAP) was:
   • the second leading risk factors for mortality in India in 2010: ~1 million
   • The fifth leading risk factor for mortality in China in 2010: ~ 1 million
• HAP contributes to ambient PM2.5 and so is responsible for
  some proportion of the burden of disease attributed to ambient
  PM2.5
• Reducing household air pollution is necessary in some settings
  in order to improve outdoor air quality
1,234,000 Deaths Attributable to Ambient PM2.5
          by Cause in China in 2010
India: Many Cities Substantially Exceed WHO and
         Indian Air Quality Guidelines

                      India Standard: 60µg/m3
Indian Results:
          PM10 Evidence from Chennai PAPA study
Approximately 0.3% -0.6% increase in mortality per 10 µg/m3 PM10
               Similar Results in Delhi as Well…
                               Fig. 23: A comparison of the estimated RR’s for PM10 obtained from the core
                               zonal model, alternative models and sensitivity analysis.

Dr. Kalpana Balakrishnan
and colleagues HEI 2011
Short-term exposure: CAPES

                    CAP ES cities
                     CAP ES研究的城市
The Health Effects Institute
         Trusted Science Cleaner Air                    Better Health
• An independent non-profit institute providing trusted science on the
  health effects of air pollution for 30 years
• Balanced Core Support
   •   US EPA and Industry (Worldwide Motor Vehicle)
• Partnerships
   • Also WHO, ADB, Clean Air Asia, major universities and medical institutions,
     EU, US DOE, industries, foundations, others
• Independent Board and Expert Science Committees
   • Oversee and intensively peer review all science
   • International experts India, China, many others)
• Hundreds of policy-relevant studies and scientific reviews, reanalysis
  conducted around the world, with strong Asia focus
• Understanding local impacts in a global context to inform policy
GBD 2010: China (and others) have seen health progress
                 1990 to 2010: Much lower death from infectious disease
                    (tuberculosis, diarrhea, early childhood illness)

Yang GH et al.
Top 20 Mortality Risk Factors in India for 2010
   Ambient PM2.5 is 5th leading mortality risk factor

                                            Ambient PM2.5
                                            caused an
                                            estimated
                                            627,000
                                            deaths
                                             ̴ 6% of all
                                            deaths in 2010
Extensive Press on China Global Burden of Disease
           Including detailed coverage in China official
           press   - China’s toxic smog battle
                   worse than first feared
                        -Air Pollution Linked to 1.2
                        Million Premature Deaths in
                   - China's
                        ChinaAir Pollution Linked
                   To Millions Of Early Deaths
                         -City Air Makes Us Sick,
                          Chinese Tell Doctor
                   - Air Pollution Killing
                   Children and Elderly in China
                          -‘Airpocalypse’ in China: Air
                          Pollution Kills Over a Million
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