Covered and non-covered drugs - Drugs not covered - and their covered alternatives for the Aetna Standard Formulary

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Covered and
non-covered
drugs

Drugs not covered — and their covered
alternatives for the Aetna Standard Formulary
2021 Formulary Exclusions Drug List

05.03.948.1I (01/21)
The drugs on this list have been removed from your
                                                                             Key
plan’s formulary. If you continue using a drug listed
under “formulary drug removals”, you may have to                             UPPERCASE             Brand-name medicine
pay the full cost. Ask your doctor to choose one of
                                                                             lowercase italics     Generic medicine
the generic or brand formulary options from the list.

 Category
                                         Formulary drug removals              Formulary options
 Drug class

 Acromegaly                              SANDOSTATIN LAR1                     SOMATULINE DEPOT
                                         SIGNIFOR LAR1
                                         SOMAVERT1

 Allergies                               dexchlorpheniramine                  levocetirizine
 Antihistamines                          Diphen Elixir
                                         RyClora
                                         CARBINOXAMINE TABLET 6 MG

 Allergies                               BECONASE AQ                          flunisolide spray, fluticasone spray, mometasone
 Nasal Steroids / Combinations           OMNARIS                              spray, DYMISTA
                                         QNASL
                                         ZETONNA

 Anticonvulsants                         APTIOM                               carbamazepine, carbamazepine ext-rel, divalproex
                                         BRIVIACT                             sodium, divalproex sodium ext-rel, gabapentin,
                                         FYCOMPA                              lamotrigine, lamotrigine ext-rel, levetiracetam,
                                         ZONEGRAN                             levetiracetam ext-rel, oxcarbazepine, phenobarbital,
                                                                              phenytoin, phenytoin sodium extended, primidone,
                                                                              tiagabine, topiramate, valproic acid, zonisamide,
                                                                              OXTELLAR XR, TROKENDI XR, VIMPAT, XCOPRI

                                         ONFI                                 clobazam, lamotrigine, topiramate, TROKENDI XR

                                         SABRIL1                              vigabatrin

 Anti-infectives, Antibacterials         E.E.S. GRANULES                      erythromycins
 Erythromycins / Macrolides              ERYPED

 Anti-infectives, Antibacterials         CoreMino                             doxycycline hyclate 20 mg, doxycycline hyclate
 Tetracyclines                           doxycycline hyclate delayed-rel      capsule, minocycline, tetracycline
                                           tablet 200 mg
                                         doxycycline hyclate tablet 50 mg
                                           (NDC^ 72143021160 only)
                                         doxycycline hyclate tablet 75 mg
                                         doxycycline hyclate tablet 150 mg
                                         doxycycline monohydrate
                                           capsule 75 mg
                                         doxycycline monohydrate
                                           capsule 150 mg
                                         minocycline ext-rel
                                         Mondoxyne NL capsule 75 mg
                                         ACTICLATE
                                         DORYX
                                         DORYX MPC
                                         MINOCIN
                                         TARGADOX

 Anti-infectives, Antibacterials         MACRODANTIN                          nitrofurantoin
 Miscellaneous

Health benefits and health insurance plans are offered, underwritten and/or administered by Aetna Health Inc.,
Aetna Health Insurance Company of New York, Aetna HealthAssurance Pennsylvania Inc., Aetna Health
Insurance Company and/or Aetna Life Insurance Company (Aetna). In Florida by Aetna Health Inc. and/or Aetna
Life Insurance Company. In Utah and Wyoming by Aetna Health of Utah Inc. and/or Aetna Life Insurance
Company. In Maryland by Aetna Health Inc., 151 Farmington Avenue, Hartford, CT 06156. Each insurer has sole
financial responsibility for its own products.

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Category
                                       Formulary drug removals           Formulary options
 Drug class

 Anti-infectives, Antifungals          flucytosine capsule 500 mg        fluconazole

                                       posaconazole delayed-rel tablet   fluconazole, itraconazole

 Anti-infectives, Antivirals           VALCYTE                           valganciclovir
 Cytomegalovirus*

 Anti-infectives, Antivirals           BARACLUDE TABLET1                 entecavir, lamivudine, tenofovir disoproxil fumarate,
 Hepatitis B*                          EPIVIR HBV1                       BARACLUDE SOLUTION, VEMLIDY
                                       HEPSERA1

 Anti-infectives, Antivirals           MAVYRET1                          EPCLUSA (genotypes 1, 2, 3, 4, 5, 6),
 Hepatitis C*                                                            HARVONI (genotypes 1, 4, 5, 6), VOSEVI 2

                                       VIEKIRA PAK1                      EPCLUSA (genotypes 1, 2, 3, 4, 5, 6),
                                       ZEPATIER1                         HARVONI (genotypes 1, 4, 5, 6)

 Anti-infectives, Antivirals           acyclovir cream                   acyclovir capsule, acyclovir tablet, valacyclovir
 Herpes*                               VALTREX

 Anti-infectives, Antivirals           COMPLERA1                         ATRIPLA, BIKTARVY, GENVOYA, ODEFSEY, SYMFI,
 HIV                                   STRIBILD1                         SYMFI LO, SYMTUZA, TRIUMEQ

 Anti-infectives                       DARAPRIM                          pyrimethamine
 Miscellaneous

 Antiobesity                           CONTRAVE                          SAXENDA
                                       QSYMIA

 Anxiety*                              XANAX                             alprazolam, clonazepam, diazepam, lorazepam,
 Benzodiazepines                       XANAX XR                          oxazepam

 Asthma*                               PROAIR HFA                        albuterol sulfate CFC-free aerosol, levalbuterol
 Beta Agonists, Short-Acting           PROAIR RESPICLICK                 tartrate CFC-free aerosol
                                       PROVENTIL HFA
                                       VENTOLIN HFA
                                       XOPENEX HFA

 Asthma*                               SINGULAIR                         montelukast, zafirlukast, zileuton ext-rel
 Leukotriene Modulators

 Asthma*                               ALVESCO                           ARNUITY ELLIPTA, FLOVENT DISKUS,
 Steroid Inhalants                     ASMANEX                           FLOVENT HFA, PULMICORT FLEXHALER,
                                       ASMANEX HFA                       QVAR REDIHALER

 Asthma* or Chronic Obstructive        DULERA                            ADVAIR DISKUS, ADVAIR HFA, BREO ELLIPTA,
   Pulmonary Disease (COPD)*                                             SYMBICORT
 Steroid / Beta Agonist Combinations

 Attention Deficit Hyperactivity       ADZENYS ER                        amphetamine-dextroamphetamine mixed salts
 Disorder*                             ADZENYS XR-ODT                    ext-rel †, methylphenidate ext-rel †, MYDAYIS,
                                       APTENSIO XR                       VYVANSE
                                       DAYTRANA

                                       EVEKEO                            amphetamine-dextroamphetamine mixed salts,
                                                                         methylphenidate

                                       INTUNIV                           amphetamine-dextroamphetamine mixed
                                                                         salts ext-rel †, atomoxetine, guanfacine ext-rel,
                                                                         methylphenidate ext-rel †, MYDAYIS, VYVANSE

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Category
                                       Formulary drug removals        Formulary options
 Drug class

 Autoimmune Agents                     CIMZIA1                        COSENTYX, ENBREL, HUMIRA
 Ankylosing Spondylitis*               SIMPONI1
                                       TALTZ1

 Autoimmune Agents                     CIMZIA1                        HUMIRA, STELARA SUBCUTANEOUS #
 Crohn's Disease*                      ENTYVIO1

 Autoimmune Agents                     CIMZIA1                        HUMIRA, OTEZLA, SKYRIZI, STELARA
 Psoriasis*                            COSENTYX1                      SUBCUTANEOUS, TALTZ, TREMFYA
                                       ENBREL1

 Autoimmune Agents                     CIMZIA1                        COSENTYX, ENBREL, HUMIRA, OTEZLA
 Psoriatic Arthritis*                  ORENCIA CLICKJECT1
                                       ORENCIA INTRAVENOUS1
                                       ORENCIA SUBCUTANEOUS1
                                       SIMPONI1
                                       STELARA SUBCUTANEOUS1
                                       TALTZ1
                                       TREMFYA1
                                       XELJANZ1
                                       XELJANZ XR1

 Autoimmune Agents                     ACTEMRA1                       ENBREL, HUMIRA, KEVZARA, ORENCIA
 Rheumatoid Arthritis*                 CIMZIA1                        CLICKJECT, ORENCIA SUBCUTANEOUS,
                                       KINERET1                       RINVOQ, XELJANZ, XELJANZ XR
                                       ORENCIA INTRAVENOUS1
                                       SIMPONI1

 Autoimmune Agents                     ENTYVIO1                       HUMIRA, STELARA SUBCUTANEOUS #,
 Ulcerative Colitis*                   SIMPONI1                       XELJANZ #, XELJANZ XR

 Autoimmune Agents                     ACTEMRA1                       ENBREL, HUMIRA
 All Other Conditions*                 KINERET1
                                       ORENCIA CLICKJECT1
                                       ORENCIA INTRAVENOUS1
                                       ORENCIA SUBCUTANEOUS1

 Cancer                                GLEEVEC1                       imatinib mesylate, BOSULIF, SPRYCEL
 Chronic Myelogenous Leukemia*         TASIGNA1

 Cancer                                BORTEZOMIB1                    NINLARO, VELCADE
 Multiple Myeloma*                     KYPROLIS1
 Proteasome Inhibitors

 Cancer                                ALIQOPA1                       COPIKTRA
 PI3K Inhibitors for                   ZYDELIG1
 Follicular Lymphoma*

 Cancer                                NILANDRON                      abiraterone, bicalutamide, XTANDI, YONSA
 Prostate*                             ZYTIGA1
 Hormonal Agents, Antiandrogens

 Cancer                                LUPRON DEPOT1                  ELIGARD
 Prostate*                               (For Prostate Cancer Only)
 Hormonal Agents,
 Luteinizing Hormone-Releasing
   Hormone (LHRH) Agonists

 Cardiovascular                        BETAPACE                       sotalol
 Antiarrhythmics                       BETAPACE AF

# after failure of HUMIRA
Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Category
                                       Formulary drug removals        Formulary options
 Drug class

 Cardiovascular                        ZETIA                          ezetimibe
 Antilipemics
 Cholesterol Absorption Inhibitors

 Cardiovascular                        fenofibrate tablet 120 mg      fenofibrate (except fenofibrate tablet 120 mg),
 Antilipemics                          FENOGLIDE TABLET 120 MG        fenofibric acid delayed-rel
                                       TRICOR
 Fibrates

 Cardiovascular                        ALTOPREV                       atorvastatin, ezetimibe-simvastatin, fluvastatin,
 Antilipemics                          CRESTOR                        lovastatin, pravastatin, rosuvastatin, simvastatin
                                       LESCOL XL
 HMG-CoA Reductase Inhibitors          LIPITOR
  (HMGs or Statins) / Combinations3    LIVALO

 Cardiovascular                        niacin tablet 500 mg           niacin ext-rel
 Antilipemics                          Niacor
 Niacins

 Cardiovascular                        REPATHA1                       PRALUENT
 Antilipemics
 PCSK9 Inhibitors

 Cardiovascular                        LANOXIN TABLET                 digoxin
 Digitalis Glycosides                    (125 MCG and 250 MCG only)

 Cardiovascular                        DYRENIUM                       amiloride, triamterene
 Diuretics

 Cardiovascular                        isosorbide dinitrate 40 mg     isosorbide dinitrate (except isosorbide
 Nitrates                                                             dinitrate 40 mg), isosorbide mononitrate

 Cardiovascular                        LETAIRIS1                      ambrisentan, bosentan, OPSUMIT
 Pulmonary Arterial Hypertension       TRACLEER1
 Endothelin Receptor Antagonists

 Cardiovascular                        ADCIRCA1                       sildenafil, tadalafil
 Pulmonary Arterial Hypertension*      REVATIO1
 Phosphodiesterase Inhibitors

 Carnitine Deficiency                  CARNITOR                       levocarnitine
                                       CARNITOR SF

 Chronic Obstructive Pulmonary         INCRUSE ELLIPTA                SPIRIVA, YUPELRI
  Disease (COPD)*                      TUDORZA
 Anticholinergics

 Chronic Obstructive Pulmonary         BEVESPI AEROSPHERE             ANORO ELLIPTA, STIOLTO RESPIMAT
  Disease (COPD)*
 Anticholinergic / Beta Agonist
  Combinations
 Long Acting

 Contraceptives                        BEYAZ                          ethinyl estradiol-drospirenone,
 Monophasic                            MINASTRIN 24 FE                ethinyl estradiol-drospirenone-levomefolate,
                                       TAYTULLA                       ethinyl estradiol-norethindrone acetate,
                                       YAZ                            ethinyl estradiol-norethindrone acetate-iron

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Category
                                        Formulary drug removals           Formulary options
 Drug class

 Contraceptives                         NATAZIA                           ethinyl estradiol-drospirenone,
 Four Phase                                                               ethinyl estradiol-drospirenone-levomefolate,
                                                                          ethinyl estradiol-levonorgestrel,
                                                                          ethinyl estradiol-norethindrone acetate,
                                                                          ethinyl estradiol-norethindrone acetate-iron,
                                                                          ethinyl estradiol-norgestimate, LO LOESTRIN FE

 Contraceptives                         LILETTA1                          KYLEENA, MIRENA, SKYLA
 Progestin Intrauterine Devices

 Contraceptives                         NUVARING                          ethinyl estradiol-etonogestrel, ANNOVERA
 Vaginal

 Cystic Fibrosis*                       TOBI1                             tobramycin inhalation solution, BETHKIS
 Inhaled Antibiotics                    TOBI PODHALER1

 Dental                                 PREVIDENT                         Consult doctor
 Cavity/Caries Prevention

 Depression*                            fluoxetine tablet 60 mg           citalopram, escitalopram, fluoxetine
 Antidepressants, Selective Serotonin   LEXAPRO                           (except fluoxetine tablet 60 mg, fluoxetine
  Reuptake Inhibitors (SSRIs)           PAXIL                             tablet [generics for SARAFEM]), paroxetine HCl,
                                        PAXIL CR                          paroxetine HCl ext-rel, sertraline, TRINTELLIX
                                        PEXEVA
                                        PROZAC
                                        VIIBRYD

 Depression*                            venlafaxine ext-rel tablet        desvenlafaxine ext-rel, duloxetine, venlafaxine,
 Antidepressants, Serotonin               (except 225 mg)                 venlafaxine ext-rel capsule
  Norepinephrine Reuptake Inhibitors    CYMBALTA
  (SNRIs)                               EFFEXOR XR
                                        PRISTIQ

 Depression*                            bupropion ext-rel tablet 450 mg   bupropion, bupropion ext-rel
 Antidepressants,                       APLENZIN                          (except bupropion ext-rel tablet 450 mg)
 Miscellaneous Agents                   OLEPTRO                           trazodone

 Depression and/or Schizophrenia*       ABILIFY                           aripiprazole, clozapine, olanzapine, quetiapine,
 Antipsychotics, Atypicals              FANAPT                            quetiapine ext-rel, risperidone, ziprasidone,
                                        SEROQUEL XR                       LATUDA, VRAYLAR

                                        INVEGA SUSTENNA                   ABILIFY MAINTENA, PERSERIS

 Dermatology                            clindamycin gel                   adapalene, benzoyl peroxide, clindamycin gel
 Acne*                                     (NDC^ 68682046275 only)        (except NDC^ 68682046275), clindamycin
                                        Vanoxide-HC                       solution, clindamycin-benzoyl peroxide,
                                        ACANYA                            erythromycin solution, erythromycin-benzoyl
                                        AZELEX                            peroxide, tretinoin, EPIDUO, ONEXTON
                                        BENZACLIN
                                        DIFFERIN LOTION
                                        FABIOR
                                        TAZORAC
                                        VELTIN
                                        ZIANA

 Dermatology                            fluorouracil cream 0.5%           fluorouracil cream 5%, fluorouracil solution,
 Actinic Keratosis*                     CARAC                             imiquimod, PICATO, TOLAK, ZYCLARA

 Dermatology                            mupirocin cream                   gentamicin, mupirocin ointment
 Antibiotics

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Category
                                       Formulary drug removals       Formulary options
 Drug class

 Dermatology                           calcipotriene cream           calcipotriene ointment, calcipotriene solution
 Antipsoriatics                        calcitriol ointment
                                       SORILUX
                                       TAZORAC
                                       VECTICAL

                                       calcipotriene-betamethasone   calcipotriene ointment or calcipotriene solution
                                                                     WITH desoximetasone, fluocinonide (except
                                                                     fluocinonide cream 0.1%) or BRYHALI

 Dermatology                           doxepin cream                 desonide, hydrocortisone, pimecrolimus,
 Atopic Dermatitis*                                                  tacrolimus, EUCRISA

 Dermatology                           doxycycline monohydrate       ORACEA
 Rosacea*                                delayed-rel capsule

                                       FINACEA GEL                   azelaic acid gel, metronidazole, FINACEA FOAM,
                                       MIRVASO                       SOOLANTRA
                                       NORITATE

 Dermatology                           BEAU RX                       Consult doctor
 Scars                                 CICATRACE
                                       POLYTOZA
                                       RECEDO
                                       SCARSILK PAD
                                       SIL-K PAD
                                       SILIVEX
                                       SILTREX

 Dermatology                           ketoconazole foam 2%          ketoconazole shampoo 2%,
 Seborrheic Dermatitis*                Ketodan                       selenium sulfide lotion 2.5%

                                       XOLEGEL                       ciclopirox, ketoconazole cream 2%

 Dermatology                           clobetasol spray              clobetasol foam
 Skin Inflammation and Hives*          CLOBEX SPRAY
                                       OLUX-E
 Corticosteroids
                                       fluocinonide cream 0.1%       clobetasol cream

                                       flurandrenolide lotion        desonide, hydrocortisone
                                          (NDC^ 24470092112 only)

                                       flurandrenolide ointment      hydrocortisone butyrate cream, hydrocortisone
                                       hydrocortisone butyrate       butyrate lotion, hydrocortisone butyrate ointment,
                                          lipophilic cream 0.1%      hydrocortisone butyrate solution, mometasone,
                                       triamcinolone acetonide       triamcinolone cream, triamcinolone lotion,
                                          aerosol 0.2%               triamcinolone ointment
                                       CORDRAN OINTMENT

                                       diflorasone cream             desoximetasone, fluocinonide (except fluocinonide
                                       diflorasone ointment          cream 0.1%), BRYHALI
                                       APEXICON E
                                       PSORCON

 Dermatology                           VEREGEN                       imiquimod
 Warts

 Dermatology                           ALEVICYN GEL                  desonide, hydrocortisone
 Wound Care Products                   ALEVICYN SG
                                       ALEVICYN SOLUTION

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Category
                                       Formulary drug removals          Formulary options
 Drug class

 Dermatology                           ALCORTIN A                       desonide, hydrocortisone
 Miscellaneous Skin Conditions         ATOPADERM
                                       BENSAL HP
                                       EPICERAM
                                       KAMDOY
                                       NOVACORT
                                       SYNERDERM

                                       oxiconazole (NDCs^ 0168035830, ciclopirox, clotrimazole, econazole,
                                         51672135902 only)            ketoconazole cream 2%, luliconazole

 Diabetes*                             metformin ext-rel                metformin, metformin ext-rel (except
 Biguanides                              (generics for FORTAMET         generics for FORTAMET and GLUMETZA)
                                         and GLUMETZA only)
                                       FORTAMET
                                       GLUMETZA
                                       RIOMET

 Diabetes*                             NESINA                           JANUVIA
 Dipeptidyl Peptidase-4 (DPP-4)        ONGLYZA
   Inhibitors                          TRADJENTA

 Diabetes*                             JENTADUETO                       JANUMET, JANUMET XR
 Dipeptidyl Peptidase-4 (DPP-4)        JENTADUETO XR
   Inhibitor Combinations              KAZANO
                                       KOMBIGLYZE XR

                                       OSENI                            JANUMET, JANUMET XR; JANUVIA WITH
                                                                        pioglitazone

 Diabetes*                             BYDUREON                         OZEMPIC, RYBELSUS, TRULICITY, VICTOZA
 Injectable Incretin Mimetics          BYETTA

 Diabetes*                             APIDRA                           FIASP, NOVOLOG
 Insulins                              HUMALOG

                                       HUMALOG MIX 50/50                NOVOLOG MIX 70/30

                                       HUMALOG MIX 75/25                NOVOLOG MIX 70/30

                                       HUMULIN 70/304                   NOVOLIN 70/304

                                       HUMULIN N4                       NOVOLIN N4

                                       HUMULIN R4                       NOVOLIN R4

                                       NOTE: Humulin R U-500
                                        concentrate will not be
                                        subject to removal and will
                                        continue to be covered.

 Diabetes*                             LANTUS                           BASAGLAR, LEVEMIR
 Long Acting Insulins   5

 Diabetes*                             ACTOS                            pioglitazone
 Insulin Sensitizers

 Diabetes*                             INVOKANA                         FARXIGA, JARDIANCE
 Sodium-Glucose
 Co-transporter 2 (SGLT2) Inhibitors

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Category
                                        Formulary drug removals               Formulary options
 Drug class

 Diabetes*                              INVOKAMET                             SYNJARDY, SYNJARDY XR, XIGDUO XR
 Sodium-Glucose                         INVOKAMET XR
 Co-transporter 2 (SGLT2) Inhibitor /
  Biguanide Combinations

 Diabetes*                              QTERN                                 GLYXAMBI
 Sodium-Glucose
 Co-transporter 2 (SGLT2) Inhibitor /
  Dipeptidyl Peptidase-4 (DPP-4)
  Inhibitor Combinations

 Diabetes*                              NOVO NORDISK NEEDLES                  BD ULTRAFINE NEEDLES
 Supplies, Needles6                     OWEN MUMFORD NEEDLES
                                        PERRIGO NEEDLES
                                        ULTIMED NEEDLES
                                        All other insulin needles that are
                                          not BD ULTRAFINE brand

 Diabetes*                              ALLISON MEDICAL                       BD ULTRAFINE INSULIN SYRINGES
 Supplies, Syringes6                      INSULIN SYRINGES
                                        TRIVIDIA INSULIN SYRINGES
                                        ULTIMED INSULIN SYRINGES
                                        All other insulin syringes that are
                                          not BD ULTRAFINE brand

 Diabetes*                              ACCU-CHEK AVIVA PLUS               ONETOUCH ULTRA STRIPS AND KITS7,
 Supplies, Test Strips and Kits
                              7, 8        STRIPS AND KITS                  ONETOUCH VERIO STRIPS AND KITS7
                                        ACCU-CHEK COMPACT
                                          PLUS STRIPS AND KITS
                                        ACCU-CHEK GUIDE STRIPS
                                        AND KITS
                                        ACCU-CHEK SMARTVIEW
                                          STRIPS AND KITS
                                        BREEZE 2 STRIPS AND KITS
                                        CONTOUR NEXT STRIPS AND KITS
                                        CONTOUR STRIPS AND KITS
                                        FREESTYLE STRIPS AND KITS
                                        All other test strips that are not
                                          ONETOUCH brand

                                        ENLITE CONTINUOUS GLUCOSE             DEXCOM CONTINUOUS GLUCOSE MONITORING
                                          MONITORING SYSTEM                   SYSTEM
                                        EVERSENSE CONTINUOUS
                                          GLUCOSE MONITORING
                                          SYSTEM
                                        FREESTYLE LIBRE CONTINUOUS
                                          GLUCOSE MONITORING
                                          SYSTEM
                                        GUARDIAN CONNECT
                                          CONTINUOUS GLUCOSE
                                          MONITORING SYSTEM

 Dietary Supplements                    FOSTEUM                               alendronate, ibandronate, risedronate
                                        FOSTEUM PLUS

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Category
                                       Formulary drug removals      Formulary options
 Drug class

 Dietary Supplements                   Activite                     folic acid
 (continued)                           DaVite
                                       Dexifol
                                       Folvik-D
                                       Folvite-D
                                       Genicin Vita-S
                                       HylaVite
                                       Lorid
                                       TronVite
                                       Vitasure
                                       Xvite
                                       FERIVA 21/7
                                       FOLIC-K
                                       NICADAN
                                       NICAPRIN
                                       NICAZEL
                                       NICAZEL FORTE
                                       NICOMIDE
                                       OMNIVEX
                                       ORTHO D
                                       ORTHO DF
                                       RHEUMATE
                                       RIBOZEL
                                       TALIVA
                                       XYZBAC
                                       ZYVIT

                                       MultiPro                     Consult doctor
                                       PRODIGEN
                                       VASCULERA

 Erectile Dysfunction*                 CIALIS                       sildenafil, tadalafil
 Phosphodiesterase Inhibitors          STENDRA
                                       VIAGRA

 Estrogen Replacement*                 MINIVELLE                    estradiol, DIVIGEL, EVAMIST
                                       VIVELLE-DOT

 Fertility*                            FOLLISTIM AQ1                GONAL-F

                                       CHORIONIC GONADOTROPIN1      OVIDREL
                                       NOVAREL1
                                       PREGNYL1

 Gastrointestinal                      chlordiazepoxide-clidinium   dicyclomine
 Anticholinergics                        (NDC^ 42494040901 only)
                                       GLYCOPYRROLATE
                                         TABLET 1.5 MG

 Gastrointestinal                      ENTERAGAM                    alosetron, VIBERZI, XIFAXAN 550 MG
 Antidiarrheals
                                       MYTESI                       diphenoxylate-atropine, loperamide

 Gastrointestinal                      TRANSDERM SCOP               meclizine, scopolamine transdermal
 Antiemetics
                                       ZUPLENZ                      granisetron, ondansetron, SANCUSO

 Gastrointestinal                      AMITIZA                      LINZESS, MOVANTIK, SYMPROIC
 Irritable Bowel Syndrome
                                       TRULANCE                     LINZESS

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Category
                                       Formulary drug removals         Formulary options
 Drug class

 Gastrointestinal                      LACTULOSE PAK                   lactulose solution
 Laxatives
                                       GOLYTELY                        peg 3350-electrolytes, CLENPIQ
                                       MOVIPREP
                                       OSMOPREP
                                       SUPREP

 Gastrointestinal                      PROVAD                          Consult doctor
 Probiotics                            ZELAC

 Gastrointestinal                      omeprazole-sodium bicarbonate   esomeprazole, lansoprazole, omeprazole,
 Proton Pump Inhibitors (PPIs)         ACIPHEX                         pantoprazole, DEXILANT
                                       ACIPHEX SPRINKLE
                                       NEXIUM
                                       PREVACID
                                       PROTONIX
                                       ZEGERID

 Gastrointestinal                      sucralfate suspension           sucralfate tablet
 Ulcer Treatment                       CARAFATE

 Gaucher Disease                       ELELYSO1                        CERDELGA, CEREZYME

 Genitourinary                         RIMSO-50                        Consult doctor
 Interstitial Cystitis

 Gout*                                 COLCRYS                         colchicine tablet

 Growth Hormones                       GENOTROPIN1                     NORDITROPIN
                                       HUMATROPE1
                                       NUTROPIN AQ1
                                       OMNITROPE1
                                       SAIZEN1

 Hematologic                           PRADAXA                         warfarin, ELIQUIS, XARELTO
 Anticoagulants (oral)

 Hematologic                           EPOGEN1                         ARANESP, RETACRIT
 Erythropoiesis-Stimulating Agents     PROCRIT1

 Hematologic                           ELOCTATE1                       ADYNOVATE, JIVI, KOGENATE FS, KOVALTRY,
 Hemophilia A                                                          NOVOEIGHT, NUWIQ

 Hematologic                           ALPROLIX1                       Consult doctor
 Hemophilia B

 Hematologic                           FULPHILA1                       ZIEXTENZO
 Neutropenia Colony                    NEULASTA1
                                       NEULASTA ONPRO1
 Stimulating Factors                   UDENYCA1

                                       GRANIX1                         NIVESTYM
                                       NEUPOGEN1
                                       ZARXIO1

 Hematologic                           PLAVIX                          clopidogrel, prasugrel, BRILINTA
 Platelet Aggregation Inhibitors
                                       ZONTIVITY                       Consult doctor

 High Blood Pressure*                  ATACAND                         candesartan, irbesartan, losartan, olmesartan,
 Angiotensin II Receptor Antagonists   BENICAR                         telmisartan, valsartan
                                       DIOVAN
                                       EDARBI

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Category
                                          Formulary drug removals       Formulary options
 Drug class

 High Blood Pressure*                     ATACAND HCT                   candesartan, irbesartan, losartan, olmesartan,
 Angiotensin II Receptor                  BENICAR HCT                   telmisartan, valsartan
                                          DIOVAN HCT
 Antagonist / Diuretic Combinations       EDARBYCLOR

 High Blood Pressure*                     EXFORGE                       amlodipine-olmesartan, amlodipine-telmisartan,
 Angiotensin II Receptor                                                amlodipine-valsartan
 Antagonist / Calcium Channel Blocker
  Combinations

 High Blood Pressure*                     EXFORGE HCT                   amlodipine-valsartan-hydrochlorothiazide,
 Angiotensin II Receptor                                                olmesartan-amlodipine-hydrochlorothiazide
 Antagonist / Calcium Channel Blocker /
  Diuretic Combinations

 High Blood Pressure*                     INDERAL LA                    atenolol, carvedilol, carvedilol phosphate ext-rel,
 Beta-blockers                            INDERAL XL                    metoprolol succinate ext-rel, metoprolol tartrate,
                                          INNOPRAN XL                   nadolol, pindolol, propranolol, propranolol ext-rel,
                                          TOPROL-XL                     BYSTOLIC

 High Blood Pressure*                     DUTOPROL                      metoprolol succinate ext-rel WITH
 Beta-blocker Combinations                                              hydrochlorothiazide

 High Blood Pressure*                     NORVASC                       amlodipine
 Calcium Channel Blockers
                                          diltiazem ext-rel (generics   diltiazem ext-rel (except generics for
                                             for CARDIZEM LA only)      CARDIZEM LA)
                                          Matzim LA
                                          CARDIZEM
                                          CARDIZEM CD
                                          CARDIZEM LA

 High Blood Pressure*                     CONSENSI                      amlodipine WITH celecoxib
 Calcium Channel Blocker /
  Nonsteroidal Anti-inflammatory
  Drugs (NSAIDs) Combinations

 Huntington's Disease                     XENAZINE1                     tetrabenazine, AUSTEDO

 Immunology                               CELLCEPT1                     mycophenolate mofetil, mycophenolate sodium
 Antimetabolites                          MYFORTIC1

 Immunology                               ASTAGRAF XL1                  tacrolimus
 Calcineurin Inhibitors                   ENVARSUS XR1

 Immunology                               OTREXUP1                      RASUVO
 Disease Modifying
   Antirheumatic Agents

 Immunology                               BERINERT1                     FIRAZYR, RUCONEST
 Hereditary Angioedema*

 Immunology                               RAPAMUNE1                     everolimus, sirolimus
 Rapamycin Derivatives                    ZORTRESS1

 Inflammatory Bowel Disease (IBD)         ASACOL HD                     balsalazide, mesalamine delayed-rel, mesalamine
 Ulcerative Colitis*                      DELZICOL                      ext-rel, sulfasalazine, sulfasalazine delayed-rel,
                                          LIALDA                        PENTASA
 Aminosalicylates
                                          COLAZAL                       balsalazide

 Interferons*                             PEGASYS1                      Consult doctor

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Category
                                       Formulary drug removals           Formulary options
 Drug class

 Kidney Disease*                       lanthanum carbonate               calcium acetate, sevelamer carbonate, PHOSLYRA,
 Phosphate Binders                     FOSRENOL                          VELPHORO

 Multiple Sclerosis                    AVONEX1                           dimethyl fumarate delayed-rel, glatiramer,
                                       EXTAVIA1                          AUBAGIO, BETASERON, COPAXONE, GILENYA,
                                       PLEGRIDY1                         KESIMPTA, MAYZENT, OCREVUS, REBIF, TYSABRI,
                                       TECFIDERA1                        VUMERITY, ZEPOSIA

 Musculoskeletal                       chlorzoxazone 375 mg              cyclobenzaprine (except cyclobenzaprine
                                       chlorzoxazone 500 mg              tablet 7.5 mg)
                                         (NDC^ 73007001303 only)
                                       chlorzoxazone 750 mg
                                       cyclobenzaprine ext-rel capsule
                                       cyclobenzaprine tablet 7.5 mg
                                       Fexmid
                                       Lorzone
                                       metaxalone 400 mg
                                       methocarbamol 500 mg
                                         (NDC^ 69036091010 only)
                                       methocarbamol 750 mg
                                         (NDCs^ 69036093090,
                                         70868090190 only)
                                       orphenadrine-aspirin-caffeine
                                       Orphengesic Forte
                                       AMRIX
                                       CHLORZOXAZONE 250 MG
                                       NORGESIC FORTE

 Narcolepsy                            NUVIGIL                           armodafinil, SUNOSI
 Wakefulness Promoters

 Nephropathic Cystinosis               PROCYSBI1                         CYSTAGON

 Ophthalmic                            ALREX                             azelastine, cromolyn sodium, olopatadine,
 Allergies                             BEPREVE                           LASTACAFT, PAZEO

 Ophthalmic                            ZYLET                             neomycin-polymyxin B-bacitracin-hydrocortisone,
 Anti-infective / Anti-inflammatory                                      neomycin-polymyxin B-dexamethasone,
                                                                         tobramycin-dexamethasone, TOBRADEX
                                                                         OINTMENT, TOBRADEX ST

 Ophthalmic                            PROLENSA                          bromfenac, diclofenac, ketorolac,
 Anti-inflammatory, Nonsteroidal                                         ACUVAIL, ILEVRO, NEVANAC

 Ophthalmic                            FML LIQUIFILM                     dexamethasone, loteprednol, prednisolone
 Anti-inflammatory, Steroidal          LOTEMAX                           acetate 1%, DUREZOL, FML FORTE, FML S.O.P.,
                                       LOTEMAX SM                        MAXIDEX, PRED MILD
                                       PRED FORTE

 Ophthalmic                            ZIRGAN                            trifluridine
 Antivirals

 Ophthalmic                            LACRISERT                         RESTASIS, XIIDRA
 Artificial Tears

 Ophthalmic                            bimatoprost solution 0.03%        latanoprost, travoprost, LUMIGAN, ZIOPTAN
 Glaucoma
                                       TIMOPTIC OCUDOSE                  timolol maleate solution, BETIMOL, BETOPTIC S

 Ophthalmic                            AVENOVA                           Consult doctor
 Miscellaneous

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Category
                                       Formulary drug removals      Formulary options
Drug class

Opioid Dependency                      SUBOXONE                     buprenorphine-naloxone sublingual, ZUBSOLV

Opioid Reversal                        EVZIO                        naloxone injection, NARCAN NASAL SPRAY

Osteoarthritis*                        GEL-ONE1                     DUROLANE, EUFLEXXA, GELSYN-3, SUPARTZ FX
Viscosupplements                       HYALGAN1
                                       MONOVISC1
                                       ORTHOVISC1
                                       SYNVISC1
                                       SYNVISC-ONE1
                                       VISCO-31

Osteoporosis*                          MIACALCIN INJECTION          alendronate, calcitonin-salmon, ibandronate,
Calcium Regulators                                                  risedronate, FORTEO, PROLIA, TYMLOS

                                       MIACALCIN NASAL SPRAY        calcitonin-salmon

Otic                                   CIPRO HC                     ciprofloxacin-dexamethasone, ofloxacin otic
Anti-infective / Anti-inflammatory     CIPRODEX

Overactive Bladder / Incontinence*     DETROL LA                    darifenacin ext-rel, oxybutynin ext-rel, solifenacin,
Urinary Antispasmodics                 ENABLEX                      tolterodine, tolterodine ext-rel, trospium,
                                       OXYTROL                      trospium ext-rel, MYRBETRIQ, TOVIAZ

Pain                                   Bupap                        diclofenac sodium, ibuprofen, naproxen
Headache*                              butalbital-acetaminophen     (except naproxen CR or naproxen suspension)
                                         tablet 50-300 mg
                                       butalbital-acetaminophen-
                                         caffeine capsule
                                       Vanatol LQ
                                       Vanatol S
                                       BUTALBITAL-ACETAMINOPHEN
                                         (NDC^ 69499034230 only)
                                       CAMBIA
                                       FIORICET CAPSULE

                                       dihydroergotamine spray      eletriptan, naratriptan, rizatriptan, sumatriptan,
                                       ergotamine-caffeine          zolmitriptan, NURTEC ODT, ONZETRA XSAIL,
                                       Migergot                     REYVOW, UBRELVY, ZEMBRACE SYMTOUCH,
                                       CAFERGOT                     ZOMIG NASAL SPRAY

                                       sumatriptan-naproxen         diclofenac sodium, ibuprofen or naproxen
                                       TREXIMET                     (except naproxen CR or naproxen suspension)
                                                                    WITH eletriptan, naratriptan, rizatriptan,
                                                                    sumatriptan, zolmitriptan, NURTEC ODT,
                                                                    ONZETRA XSAIL, REYVOW, UBRELVY,
                                                                    ZEMBRACE SYMTOUCH or ZOMIG NASAL SPRAY

Pain                                   BUTRANS                      buprenorphine transdermal, BELBUCA
Opioid Analgesics
                                       LAZANDA                      fentanyl transmucosal lozenge, SUBSYS

                                       levorphanol                  fentanyl transdermal, hydrocodone ext-rel,
                                       oxymorphone ext-rel          hydromorphone ext-rel, methadone, morphine
                                       HYSINGLA ER                  ext-rel, NUCYNTA ER, XTAMPZA ER
                                       OXYCONTIN
                                       ZOHYDRO ER

                                       PERCOCET                     hydrocodone-acetaminophen, hydromorphone,
                                       PRIMLEV                      morphine, oxycodone-acetaminophen, NUCYNTA

                                       tramadol                     tramadol (except NDC^ 52817019610),
                                          (NDC^ 52817019610 only)   tramadol ext-rel

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Category
                                        Formulary drug removals         Formulary options
 Drug class

 Pain                                   LIDOCAINE-TETRACAINE CREAM lidocaine-prilocaine
 Topical Local Anesthetics                (NDC^ 71800063115 only)
                                        LIDOTREX

 Pain and Inflammation*                 MILLIPRED                       dexamethasone, hydrocortisone,
 Corticosteroids                        RAYOS                           methylprednisolone, prednisolone solution,
                                                                        prednisone

 Pain and Inflammation*                 ARTHROTEC                       celecoxib; diclofenac sodium, ibuprofen, meloxicam
 Nonsteroidal Anti-inflammatory Drugs                                   or naproxen (except naproxen CR or naproxen
  (NSAIDs) / Combinations                                               suspension) WITH esomeprazole, lansoprazole,
                                                                        omeprazole, pantoprazole or DEXILANT

                                        Diclofex DC                     diclofenac sodium, diclofenac sodium gel 1%,
                                           (NDC^ 51021037201 only)      diclofenac sodium solution, ibuprofen,
                                        Diclosaicin                     meloxicam, naproxen (except naproxen CR or
                                        Inflammacin                     naproxen suspension)
                                        NuDiclo SoluPak
                                        NuDiclo TabPak
                                        PENNSAID

                                        fenoprofen                      diclofenac sodium, ibuprofen, meloxicam, naproxen
                                        indomethacin capsule 20 mg      (except naproxen CR or naproxen suspension)
                                        ketoprofen capsule 25 mg
                                        ketoprofen ext-rel capsule
                                        mefenamic acid
                                          (NDC^ 69336012830 only)
                                        naproxen CR
                                        naproxen suspension
                                        FENOPROFEN CAPSULE
                                        INDOCIN
                                        NAPRELAN
                                        SPRIX
                                        ZORVOLEX

                                        naproxen-esomeprazole           diclofenac sodium, ibuprofen, meloxicam or
                                                                        naproxen (except naproxen CR or naproxen
                                                                        suspension) WITH esomeprazole, lansoprazole,
                                                                        omeprazole, pantoprazole or DEXILANT

 Parkinson’s Disease                    APOKYN1                         INBRIJA

 Postherpetic Neuralgia                 HORIZANT                        gabapentin, GRALISE

 Prostate Condition                     JALYN                           dutasteride-tamsulosin; dutasteride or finasteride
 Benign Prostatic Hyperplasia*                                          WITH alfuzosin ext-rel, doxazosin, silodosin,
                                                                        tamsulosin or terazosin

                                        RAPAFLO                         alfuzosin ext-rel, doxazosin, silodosin, tamsulosin,
                                        UROXATRAL                       terazosin

 Respiratory                            ARALAST NP1                     PROLASTIN-C
 Alpha-1 Antitrypsin Deficiency         GLASSIA1
                                        ZEMAIRA1

 Respiratory                            benzonatate (NDCs^ 69336012615, benzonatate (except NDCs^ 69336012615,
 Cough                                    69499032915 only)             69499032915)

 Sleep Disorder                         quazepam                        doxepin, eszopiclone, ramelteon, zolpidem,
 Hypnotics, Non-benzodiazepines         INTERMEZZO                      zolpidem ext-rel, zolpidem sublingual, BELSOMRA
                                        LUNESTA
                                        ROZEREM
                                        ZOLPIMIST

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Category
                                       Formulary drug removals           Formulary options
 Drug class

 Testosterone Replacement*             testosterone gel 1% (authorized   testosterone gel (except authorized generics for
 Androgens                               generics for TESTIM and         TESTIM and VOGELXO), testosterone solution,
                                         VOGELXO only)                   ANDRODERM
                                       ANDROGEL 1%
                                       FORTESTA
                                       NATESTO
                                       TESTIM
                                       VOGELXO

 Thyroid Supplements                   TIROSINT                          levothyroxine, SYNTHROID

 Transplant*                           PROGRAF1                          tacrolimus
 Immunosuppressants,
   Calcineurin Inhibitors

 Urea Cycle Disorders                  BUPHENYL1                         sodium phenylbutyrate
                                       RAVICTI1

 Women’s Health                        MENEST                            estradiol
 Menopausal Symptom Agents             OSPHENA
                                       PREMARIN
 Oral

 Women’s Health                        ESTRING                           estradiol, IMVEXXY
 Menopausal Symptom Agents             FEMRING
                                       INTRAROSA
 Vaginal                               PREMARIN CREAM

 Women’s Health                        fluoxetine tablet                 fluoxetine (except fluoxetine tablet 60 mg,
 Premenstrual Dysphoric Disorder          (generics for SARAFEM only)    fluoxetine tablet [generics for SARAFEM]),
   (PMDD)                                                                paroxetine HCl ext-rel, sertraline

 Women’s Health                        AZESCO                            prenatal vitamins, CITRANATAL
 Prenatal Vitamins                     ZALVIT

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
Drug class                Other considerations

 All Drugs                 On a quarterly basis, new and existing products - including limited source generics, products
                           with significant cost inflation, and specialty and non-specialty products - may be re-evaluated
                           to determine appropriate formulary placement. These evaluations will assess whether clinically
                           appropriate and cost-effective options remain available on the formulary and may result in removal,
                           addition or deletion of a product.

 Autoimmune and            For some clients, an Indication-Based Formulary will be utilized for products in these classes and may
  Hepatitis C*             result in additional removals for certain conditions only.

 Drugs for Infusion        A drug that must be infused into a space other than the blood will generally not be covered under the
   Into Spaces Other       prescription drug benefit.
   Than the Blood

 New-to-Market Agents1     New-to-market products and new variations of products already in the marketplace will not be added
                           to the formulary immediately. Each product will be evaluated for clinical appropriateness and cost-
                           effectiveness. Recommended additions to the formulary will be presented to the CVS Caremark®
                           National Pharmacy and Therapeutics Committee (or other appropriate reviewing body) for review
                           and approval.

The listed formulary options are subject to change.

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
List of formulary drug removals

 ABILIFY                      BEPREVE                          CRESTOR                         EVERSENSE CONTINUOUS
 ACANYA                       BERINERT1                        cyclobenzaprine ext-rel            GLUCOSE MONITORING
 ACCU-CHEK AVIVA PLUS         BETAPACE                            capsule                         SYSTEM
   STRIPS AND KITS8           BETAPACE AF                      cyclobenzaprine tablet 7.5 mg   EVZIO
 ACCU-CHEK COMPACT PLUS       BEVESPI AEROSPHERE               CYMBALTA                        EXFORGE
   STRIPS AND KITS8           BEYAZ                            DARAPRIM                        EXFORGE HCT
 ACCU-CHEK GUIDE STRIPS       bimatoprost solution 0.03%       DaVite                          EXTAVIA1
   AND KITS8                  BORTEZOMIB1                      DAYTRANA                        FABIOR
 ACCU-CHEK SMARTVIEW          BREEZE 2 STRIPS AND KITS8        DELZICOL                        FANAPT
   STRIPS AND KITS8           BRIVIACT                         DETROL LA                       FEMRING
                              Bupap                            dexchlorpheniramine             fenofibrate tablet 120 mg
 ACIPHEX
                              BUPHENYL1                        Dexifol                         FENOGLIDE TABLET 120 MG
 ACIPHEX SPRINKLE                                              Diclofex DC
                              bupropion ext-rel                                                fenoprofen
 ACTEMRA1                        tablet 450 mg                    (NDC^ 51021037201 only)
 ACTICLATE                                                                                     FENOPROFEN CAPSULE
                              butalbital-acetaminophen         Diclosaicin
 Activite                                                                                      FERIVA 21/7
                                 tablet 50-300 mg              DIFFERIN LOTION                 Fexmid
 ACTOS                        BUTALBITAL-                      diflorasone cream
 acyclovir cream                                                                               FINACEA GEL
                                 ACETAMINOPHEN                 diflorasone ointment
 ADCIRCA1                                                                                      FIORICET CAPSULE
                                 (NDC^ 69499034230 only)       dihydroergotamine spray
                                                                                               flucytosine capsule 500 mg
 ADZENYS ER                   butalbital-acetaminophen-        diltiazem ext-rel (generics     fluocinonide cream 0.1%
 ADZENYS XR-ODT                  caffeine capsule                 for CARDIZEM LA only)        fluorouracil cream 0.5%
 ALCORTIN A                   BUTRANS                          DIOVAN                          fluoxetine tablet (generics
 ALEVICYN GEL                 BYDUREON                         DIOVAN HCT                         for SARAFEM only)
 ALEVICYN SG                  BYETTA                           Diphen Elixir                   fluoxetine tablet 60 mg
 ALEVICYN SOLUTION            CAFERGOT                         DORYX                           flurandrenolide lotion
                              calcipotriene cream              DORYX MPC                          (NDC^ 24470092112 only)
 ALIQOPA1
                              calcipotriene-betamethasone      doxepin cream                   flurandrenolide ointment
 ALLISON MEDICAL
                              calcitriol ointment              doxycycline hyclate             FML LIQUIFILM
   INSULIN SYRINGES6
                              CAMBIA                              delayed-rel tablet 200 mg    FOLIC-K
 ALPROLIX1                                                                                     FOLLISTIM AQ1
                              CARAC                            doxycycline hyclate
 ALREX                                                            tablet 50 mg (NDC^           Folvik-D
                              CARAFATE
 ALTOPREV                     CARBINOXAMINE                       72143021160 only)            Folvite-D
 ALVESCO                         TABLET 6 MG                   doxycycline hyclate             FORTAMET
 AMITIZA                      CARDIZEM                            tablet 75 mg                 FORTESTA
 AMRIX                        CARDIZEM CD                      doxycycline hyclate             FOSRENOL
 ANDROGEL1%                                                       tablet 150 mg                FOSTEUM
                              CARDIZEM LA
 APEXICON E                                                    doxycycline monohydrate         FOSTEUM PLUS
                              CARNITOR                            capsule 75 mg
 APIDRA                       CARNITOR SF                                                      FREESTYLE LIBRE
                                                               doxycycline monohydrate
 APLENZIN                     CELLCEPT1                                                           CONTINUOUS GLUCOSE
                                                                  capsule 150 mg
 APOKYN1                      chlordiazepoxide-clidinium       doxycycline monohydrate            MONITORING SYSTEM
 APTENSIO XR                     (NDC^ 42494040901 only)          delayed-rel capsule          FREESTYLE STRIPS AND KITS8
 APTIOM                       CHLORZOXAZONE 250 MG             DULERA                          FULPHILA1
 ARALAST NP1                  chlorzoxazone 375 mg                                             FYCOMPA
                                                               DUTOPROL
 ARTHROTEC                    chlorzoxazone 500 mg (NDC^                                       GEL-ONE1
                                 73007001303 only)             DYRENIUM
 ASACOL HD                                                                                     Genicin Vita-S
                              chlorzoxazone 750 mg             EDARBI
 ASMANEX                                                                                       GENOTROPIN1
                              CHORIONIC GONADOTROPIN1          EDARBYCLOR
 ASMANEX HFA                                                                                   GLASSIA1
                              CIALIS                           E.E.S. GRANULES
 ASTAGRAF XL1                                                                                  GLEEVEC1
                              CICATRACE                        EFFEXOR XR
 ATACAND                                                                                       GLUMETZA
                              CIMZIA1                          ELELYSO1
 ATACAND HCT                                                                                   GLYCOPYRROLATE
                              CIPRO HC                         ELOCTATE1
 ATOPADERM                                                                                        TABLET 1.5 MG
                              CIPRODEX                         ENABLEX
 AVENOVA                                                                                       GOLYTELY
                              clindamycin gel (NDC^            ENLITE CONTINUOUS
 AVONEX1                         68682046275 only)                                             GRANIX1
                                                                  GLUCOSE MONITORING           GUARDIAN CONNECT
 AZELEX                       clobetasol spray
                              CLOBEX SPRAY                        SYSTEM                          CONTINUOUS GLUCOSE
 AZESCO
                              COLAZAL                          ENTERAGAM                          MONITORING SYSTEM
 BARACLUDE TABLET1
                              COLCRYS                          ENTYVIO1                        HEPSERA1
 BEAU RX
                              COMPLERA1                        ENVARSUS XR1                    HORIZANT
 BECONASE AQ
 BENICAR                      CONSENSI                         EPICERAM                        HUMALOG
 BENICAR HCT                  CONTOUR NEXT STRIPS AND          EPIVIR HBV1                     HUMALOG MIX 50/50
 BENSAL HP                       KITS 8                        EPOGEN1                         HUMALOG MIX 75/25
                              CONTOUR STRIPS AND KITS8         ergotamine-caffeine             HUMATROPE1
 BENZACLIN
 benzonatate                  CONTRAVE                         ERYPED                          HUMULIN 70/304
   (NDCs^ 69336012615,        CORDRAN OINTMENT                 ESTRING                         HUMULIN N4
   69499032915 only)          CoreMino                         EVEKEO                          HUMULIN R4

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
List of Formulary Drug Removals

 HYALGAN1                     metformin ext-rel                Orphengesic Forte       ROZEREM
 hydrocortisone butyrate        (generics for FORTAMET         ORTHO D                 RyClora
    lipophilic cream 0.1%       and GLUMETZA only)             ORTHO DF                SABRIL1
 HylaVite                     methocarbamol 500 mg             ORTHOVISC1              SAIZEN1
 HYSINGLA ER                    (NDC^ 69036091010 only)                                SANDOSTATIN LAR1
                              methocarbamol 750 mg             OSENI
 INCRUSE ELLIPTA                                               OSMOPREP                SCARSILK PAD
                                (NDCs^ 69036093090,
 INDERAL LA                                                    OSPHENA                 SEROQUEL XR
                                70868090190 only)
 INDERAL XL                                                    OTREXUP1                SIGNIFOR LAR1
                              MIACALCIN INJECTION
 INDOCIN                      MIACALCIN NASAL SPRAY            OWEN MUMFORD NEEDLES6   SIL-K PAD
 indomethacin capsule 20 mg   Migergot                         oxiconazole             SILIVEX
 Inflammacin                                                     (NDCs^ 00168035830,   SILTREX
                              MILLIPRED
 INNOPRAN XL                                                     51672135902 only)     SIMPONI1
                              MINASTRIN 24 FE
 INTERMEZZO                                                    OXYCONTIN               SINGULAIR
                              MINIVELLE
 INTRAROSA                                                     oxymorphone ext-rel     SOMAVERT1
                              MINOCIN
 INTUNIV                      minocycline ext-rel              OXYTROL                 SORILUX
 INVEGA SUSTENNA              MIRVASO                          PAXIL                   SPRIX
 INVOKAMET                    Mondoxyne NL capsule 75 mg       PAXIL CR                STENDRA
 INVOKAMET XR                 MONOVISC1                        PEGASYS1                STRIBILD1
 INVOKANA                     MOVIPREP                         PENNSAID                SUBOXONE
 isosorbide dinitrate 40 mg   MultiPro                         PERCOCET                sucralfate suspension
 JALYN                        mupirocin cream                  PERRIGO NEEDLES6        sumatriptan-naproxen
 JENTADUETO                   MYFORTIC1                        PEXEVA                  SUPREP
 JENTADUETO XR                MYTESI                           PLAVIX                  SYNERDERM
 KAMDOY                       NAPRELAN                         PLEGRIDY1               SYNVISC1
 KAZANO                       naproxen-esomeprazole            POLYTOZA                SYNVISC-ONE1
 ketoconazole foam 2%         naproxen CR                      posaconazole            TALIVA
 Ketodan                      naproxen suspension                delayed-rel tablet    TARGADOX
 ketoprofen capsule 25 mg     NATAZIA                          PRADAXA                 TASIGNA1
 ketoprofen ext-rel capsule   NATESTO                          PRED FORTE              TAYTULLA
 KINERET1                     NESINA                           PREGNYL1                TAZORAC
 KOMBIGLYZE XR                NEULASTA1                        PREMARIN                TECFIDERA1
 KYPROLIS1                    NEULASTA ONPRO1                  PREMARIN CREAM          TESTIM
 LACRISERT                    NEUPOGEN1                        PREVACID                testosterone gel 1%
 LACTULOSE PAK                NEXIUM                           PREVIDENT                  (authorized generics for
 LANOXIN TABLET (125 MCG      niacin tablet 500 mg             PRIMLEV                    TESTIM and VOGELXO only)
    AND 250 MCG ONLY)         Niacor                                                   TIMOPTIC OCUDOSE
                                                               PRISTIQ
 lanthanum carbonate          NICADAN
                                                               PROAIR HFA              TIROSINT
 LANTUS                       NICAPRIN
                                                               PROAIR RESPICLICK       TOBI1
 LAZANDA                      NICAZEL
                                                               PROCRIT1                TOBI PODHALER1
 LESCOL XL                    NICAZEL FORTE
                                                               PROCYSBI1               TOPROL-XL
 LETAIRIS1                    NICOMIDE                                                 TRACLEER1
                                                               PRODIGEN
 levorphanol                  NILANDRON
                                                               PROGRAF1                TRADJENTA
 LEXAPRO                      NORGESIC FORTE                                           tramadol
                                                               PROLENSA
 LIALDA                       NORITATE                                                    (NDC^ 52817019610 only)
                                                               PROTONIX
 LIDOCAINE-TETRACAINE         NORVASC                                                  TRANSDERM SCOP
                                                               PROVAD
    CREAM (NDC^               NOVACORT                                                 TREXIMET
                                                               PROVENTIL HFA
    71800063115 only)         NOVAREL1                                                 triamcinolone
                                                               PROZAC
 LIDOTREX                     NOVO NORDISK NEEDLES6                                       acetonide aerosol 0.2%
                              NuDiclo SoluPak                  PSORCON
 LILETTA1                                                                              TRICOR
                              NuDiclo TabPak                   QNASL                   TRIVIDIA INSULIN SYRINGES6
 LIPITOR
                              NUTROPIN AQ1                     QSYMIA                  TronVite
 LIVALO
 Lorid                        NUVARING                         QTERN                   TRULANCE
 Lorzone                      NUVIGIL                          quazepam                TUDORZA
 LOTEMAX                      OLEPTRO                          RAPAFLO                 UDENYCA1
                              OLUX-E                           RAPAMUNE1               ULTIMED INSULIN SYRINGES6
 LOTEMAX SM
                              omeprazole-sodium                RAVICTI1                ULTIMED NEEDLES6
 LUNESTA
                                bicarbonate                    RAYOS                   UROXATRAL
 LUPRON DEPOT1
                              OMNARIS                          RECEDO                  VALCYTE
 MACRODANTIN
 Matzim LA                    OMNITROPE1                       REPATHA1                VALTREX
 MAVYRET1                     OMNIVEX                          REVATIO1                Vanatol LQ
 mefenamic acid               ONFI                             RHEUMATE                Vanatol S
    (NDC^ 69336012830 only)   ONGLYZA                          RIBOZEL                 Vanoxide-HC
 MENEST                       ORENCIA INTRAVENOUS1             RIMSO-50                VASCULERA
 metaxalone 400 mg            orphenadrine-aspirin-caffeine    RIOMET                  VECTICAL

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
List of Formulary Drug Removals

 VELTIN                       XENAZINE1                        ZIANA
 venlafaxine ext-rel tablet   XOLEGEL                          ZIRGAN
   (except 225 mg)            XOPENEX HFA                      ZOHYDRO ER
 VENTOLIN HFA                 Xvite                            ZOLPIMIST
 VEREGEN                      XYZBAC                           ZONEGRAN
 VIAGRA                       YAZ                              ZONTIVITY
 VIEKIRA PAK1                 ZALVIT                           ZORTRESS1
 VIIBRYD                      ZARXIO1                          ZORVOLEX
 VISCO-31                     ZEGERID                          ZUPLENZ
 Vitasure                     ZELAC                            ZYDELIG1
 VIVELLE-DOT                  ZEMAIRA1                         ZYLET
 VOGELXO                      ZEPATIER1                        ZYTIGA1
 XANAX                        ZETIA                            ZYVIT
 XANAX XR                     ZETONNA

Aetna Standard Plan Formulary Exclusions Drug List (01/2021)
*
    This list indicates the common uses for which the drug is prescribed. Some drugs are prescribed for more than one
    condition.
†
    Listing does not include certain NDCs^.
^
    Drug products are identified by unique numerical product identifiers, called National Drug Codes (NDC), which identify
    the manufacturer, strength, dosage form, formulation and package size.
1
    An exception process may exist for specific clinical or regulatory circumstances that may require coverage of a
    non-covered medication. If your doctor believes you have a specific clinical need for a non-covered product, he
    or she should fax an exception request to: 1-888-487-9257.
2
    For use in patients previously treated with an HCV regimen containing an NS5A inhibitor (for genotypes 1-6) or
    sofosbuvir without an NS5A inhibitor (for genotypes 1a or 3).
3
    If approved for coverage and prescribed for primary prevention of cardiovascular disease, may be covered without
    cost sharing through an exceptions process.
4
    Rebranded or private label formulations are not covered (i.e., RELION).
5
    Long Acting Insulins - First Generation.
6
    BD ULTRAFINE syringes and needles are the only preferred options.
7
     ONETOUCH blood glucose meter may be provided at no charge by the manufacturer to those individuals
    A
    currently using a meter other than ONETOUCH. For more information on how to obtain a blood glucose meter,
    call: 1-877-418-4746.
8
    ONETOUCH brand test strips are the only preferred options.

This is not a complete list of medications covered or excluded under your plan. We only list the most common ones.
Certain drugs may not be covered by your particular pharmacy plan. Diabetic supplies may be covered under your
medical plan.
Information is believed to be accurate as of the production date; however, it is subject to change.
To check coverage and copay information for a specific medicine, log into your member website. For questions, please
call the toll free number on the back of your member ID card.

©2020 Aetna Inc.
05.03.948.1I (01/21)
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