Hidradenitis Suppurativa - Karger Publishers
←
→
Page content transcription
If your browser does not render page correctly, please read the page content below
Dermatology
236(1) 1–70 (2020) 236 | 1 | 20 print
ISSN 1018–8665
online
e-ISSN 1421–9832
www.karger.com/drm
ISBN 978–3–318–06695–1
Hidradenitis Suppurativa
Selected papers from the 8th Conference of the
European Hidradenitis Suppurativa Foundation;
6–8 February 2019 – Wroclaw, Poland
EiC/Guest Editor
Gregor B.E. Jemec, Roskilde, Denmark
Jacek C. Szepietowski, Wroclaw, Poland
S. Karger
Medical and Scientific Publishers
Basel . Freiburg . Hartford . Oxford
Bangkok . Dubai . Kuala Lumpur .
Melbourne . Mexico City .
Moscow . New Delhi . Paris .
Shanghai . TokyoA balancing act
pH of the Skin:
Current Problems in Dermatology
Editors: P. Itin, G.B.E. Jemec
Vol. 54
Issues and Challenges
pH of the Skin:
Issues and Challenges
Editors
C. Surber
C. Abels
H. Maibach
Editors
Christian Surber
4.5-5.3
7.0
serine proteases:
kallikrein 5 (KLK5) = (SCTE)
kallikrein 7 (KLK7) = (SCCE)
Christoph Abels
5.8
Β-glucocerebrosidase
acid sphingosinmyelinase
9.0
alkaline
ceramidase
6.8-7.3
DIFFERENTIATION
secretory phospholipase A2
steroid sulfatase
4 5
Normal
pH
6 7 8 9
Degradation of SC
10
pH
Howard Maibach
pH of the Skin: Issues and Challenges The concept of expressing acidity as the negative Contents
Editors: Surber, C. (Basel/Zurich); Abels, C.
(Bielefeld); Maibach, H. (San Francisco, CA)
logarithm of the hydrogen ion concentration was • Preface: Surber, C.; Abels C.; Maibach, H.
VIII + 206 p., 41 fig., 32 in color, 13 tab., 2018 defined and termed pH in the beginning of the 20th Background and Introduction
CHF 198.00 / EUR 185.00 / USD 233.00 century. The general usefulness of the pH concept • The Acid Mantle: A Myth or an Essential Part of Skin Health?
Hard cover or online prices for personal
customers
for life science was recognized and later gained im- Surber, C.; Humbert, P. Abels C.; Maibach, H.
Prices subject to change, VAT not included portance to analytical research. Reports on results of Chemistry of pH/pH Measurement
EUR price for eurozone countries, pH measurements from living skin established the • Buffering Capacity: Proksch, E.
USD price for USA and Latin America only
ISBN 978–3–318–06384–4
term acid mantle – the skin’s own protective shield • Measurement of Skin Surface pH: du Plessis, J.L.;
e-ISBN 978–3–318–06385–1 that maintains a naturally acid pH. Stefaniak, A.B.; Wilhelm, K.-P.
Physiology of the Skin pH
Current Problems in Dermatology, Vol. 54
Series Editors: Itin, P. (Basel);
It is invisible to the eye but crucial to the overall well- • Skin Surface pH in Newborns: Origin and Consequences:
being of skin. Chronic alkalization can throw this acid Fluhr, J.W.; Darlenski, R.
Jemec, G.B.E. (Roskilde)
• Intrinsic and Extrinsic Factors Affecting Skin Surface pH:
ISSN 1421–5721 / e-ISSN 1662–2944 mantle out of balance, leading to inflammation, der- Farage, W.A.; Hood, W.; Berardesca, E.; Maibach, H.
Listed in MEDLINE/PubMed
matitis, and atopic skin diseases. It is therefore no • Gender, Age, and Ethnicity as Factors That Can Influence
surprise, that skin pH shifts have been observed in Skin pH: Choi, E.H.
various skin pathologies. It is also obvious that the pH • Endogenous Factors That Can Influence Skin pH:
in topically applied preparations may play an impor- Bíró, T.; Oláh, A.; Tóth, B.I.; Szöllősi, A.G.
• Lipids in the Skin and pH: Wohlrab, J.; Gebert, A.;
tant role. Optimal pH and buffer capacity within Neubert, R.H.H.
topical preparations not only support stability of ac- • Influence of pH on Skin Stem Cells and Their
tive ingredients and auxiliary materials, but may also Differentiation: Charruyer, A.; Ghadially, R.
increase absorption of the non-ionized species of an • The Influence of Calcium on the Skin pH and Epidermal
acidic or a basic active ingredient. They may even Barrier During Aging: Rinnerthaler, M.; Richter, K.
open up opportunities to modify and “correct” skin pH in Skin Pathophysiology
pH and hence accelerate barrier recovery and main- • pH and Microbial Infections: Rippke, F.; Berardesca, E.;
tain or enhance barrier integrity. Further efforts are Weber, T.M.
• pH in Atopic Dermatitis: Danby, S.G.; Cork, M.J.
needed to standardize and improve pH measure- • Role of Skin pH in Psoriasis: Bigliardi, P.L.
ments in biological media or pharmaceutical/cos- • pH and Acne: Schürer, N.
metic vehicles to increase and ensure quality, com-
pH in Cosmetic Products/Topical Formulations
parability, and relevance of research data. • pH and Buffer Capacity of Topical Formulations:
Wohlrab, J.; Gebert, A.
Dear Librarian In this volume, we present a unique collection of pa- • The Relation of pH and Skin Cleansing: Blaak, J.; Staib, P.
pers that address past, present and future issues of • pH and Drug Delivery: Østergaard Knudsen, N.;
I have reviewed this publication and Pommergaard Pedersen, G.
would like to recommend it for our library. the pH of healthy and diseased skin. It is hoped that
• Metamorphosis of Vehicles: Mechanisms and
Recommended by: this collection will foster future efforts in clinical and Opportunities: Surber, C.; Knie, U.
experimental skin research. • Influence of Topical Formulations: Lipid Lamella
Organization and Lipid Composition of Stratum Corneum
as a Surrogate Marker for Barrier Integrity: Dähnhardt, D.;
Surber, C.; Dähnhardt-Pfeiffer, S.
Department: • Skin Care Products: Age-Appropriate Cosmetics:
Abels, C.; Angelova-Fischer, I.
• Skin Care Products for Healthy and Diseased Skin:
Surber, C.; Dragicevic, N.; Kottner, J.
Date: Author Index / Subject Index
Signature: The easiest way to order: w w w.karger.com/cpd
KI18307
Karger – Medical and Scientific Publishers
Orders may be placed with any bookshop, CH–4009 Basel, Switzerland
subscription agency, directly with the publisher orders@karger.com, f: +41 61 306 12 34
or through a Karger representative. www.karger.comAn International Journal founded as
“Dermatologische Zeitschrift” by Oskar Lassar (1893–1907)
Continued by Erich Hoffmann (1908–1938), continued as “Dermatologica” (1939–1991),
by Wilhelm Lutz (1939–1958), Rudolf Schuppli (1959–1985) and J.-H. Saurat (1986–2015),
continued as “Dermatology” since 1992
Editor-in-Chief
Gregor B.E. Jemec – Zealand University Hospital, Roskilde, Denmark
Section Editor “Atopic Dermatitis”
Tove Agner – Bispebjerg University Hospital, Copenhagen, Denmark
Section Editor “Dermato-Endocrinology”
Jörg Reichrath – Saarland University, Homburg, Germany
Section Editor “Dermoscopy and Clinical Imaging”
Giuseppe Argenziano – University of Campania, Naples, Italy
Section Editor “Genetics”
Official Organ of
Pierre Vabres – CHU Dijon Bourgogne, Dijon, France
Swiss Society for Dermatology
and Venereology Section Editor “Outcome Measures”
Schweizerische Gesellschaft für
Dermatologie und Venerologie Amit Garg – Hofstra Northwell School of Medicine, Lake Success, NY, USA
Société Suisse de
Dermatologie et Vénéréologie
Section Editor “Skin Cancer”
Ketty Peris – Catholic University, Rome, Italy
Section Editor “Tattoo and Body Art”
Jørgen Serup – Bispebjerg University Hospital, Copenhagen, Denmark
(Continued on next page)
Printed in Germany on acid-free and non-aging paper
(ISO 9706) by Stückle Druck, EttenheimAssociate Editors
Perla Calderón – University of Chile, Santiago, Chile
Lars E. French – University Hospital Munich, Munich, Germany
Robert Gniadecki – University of Alberta, Edmonton, AB, Canada
Qiang Ju – Renji Hospital, Shanghai Jiao Tong University, Shanghai, China
Brian Kirby – St. Vincent’s University Hospital, Dublin, Ireland
Dan Lipsker – University of Strasbourg, Strasbourg, France
Branka Marinović – University Hospital Center Zagreb, Zagreb, Croatia
Tetsuo Shiohara – Kyorin University, Tokyo, Japan
H. Peter Soyer – The University of Queensland, Brisbane, QLD, Australia
Dae Hun Suh – Seoul National University, Seoul, Republic of Korea
Jacek C. Szepietowski – University of Wroclaw, Wroclaw, Poland
Christos C. Zouboulis – Dessau City Clinic, Dessau, Germany
Editorial Board
Tania Cestari – Federal University of Rio Grande do Sul, Porto Alegre, Brazil
Maja-Lisa Clausen – Bispebjerg University Hospital, Copenhagen, Denmark
Veronique del Marmol – Université Libre de Bruxelles, Brussels, Belgium
Lennart Emtestam – Karolinska University Hospital and Institutet, Stockholm, Sweden
Alice Gottlieb – New York Medical College, Valhalla, NY, USA
Dimitrios Ioannides – Aristotle University Medical School, Thessaloniki, Greece
Jürgen Lademann – Charité – Universitätsmedizin Berlin, Berlin, Germany
Sirkku Peltonen – University of Turku and Turku University Hospital, Turku, Finland
Errol P. Prens – Erasmus Medical Center, Rotterdam, Netherlands
Luis Puig – Autonomous University of Barcelona, Barcelona, Spain
Jean Revuz – Private Practice – Dermatology, Paris, France
Devinder Mohan Thappa – Jawaharlal Institute of Postgraduate Medical Education and
Research, Puducherry, India
© 2020 S. Karger AG, Basel
www.karger.com
karger@karger.comJournal Information
Aims and Scope
Published since 1893, Dermatology provides a worldwide survey of clinical and investigative
dermatology. Original papers report clinical and laboratory findings. In order to inform read-
ers of the implications of recent research, reviews prepared by invited, internationally rec-
ognized scientists are regularly featured. In addition, the journal publishes papers on novel
treatments, surgical pearls, consensus guidelines and industry news.
Dermatology offers the analytical dermatologist a broad range of information, from practical
problem solving to a deeper mechanistic understanding of skin diseases, while at the same
time providing space for further hypotheses that may help to find new solutions to old prob-
lems. The journal publishes contributions from across the globe on a wide range of skin-
related topics including epidemiology, skin biology, clinical dermatology, and therapy. It
enjoys a high reputation in the field of dermatology.
ISSN Print Edition: 1018–8665
ISSN Online Edition: 1421–9832 Guidelines for Authors Journal Contact
We strongly encourage authors to read For questions or comments, please contact
Journal Homepage: www.karger.com/drm the Guidelines for Authors at the persons responsible who can be found at
Bibliographic Indices: This journal is listed in biblio- www.karger.com/drm_guidelines prior to http://www.karger.com/Journal/Contact/224164.
graphic services, including PubMed, MEDLINE, Web submitting an article.
of Science, Science Citation Index, Science Citation
Index Expanded, Current Contents – Clinical Medi-
cine, BIOSIS Previews, Google Scholar, Chemical Ab- Subscription Orders: Subscription Rates: Subscriptions run for a full
stracts Service, FSTA: Food Science and Technology Orders can be placed at agencies, bookstores, calendar year. Prices are given per year.
Abstracts, CAB Abstracts, Global Health, Scopus, Em- or directly with the Publisher.
base, Pathway Studio, CINAHL Complete, Health Re- Personal subscription:
search Premium Collection, Medical Database, S. Karger AG
Print or Online Print+Online combined
Health & Medical Collection, ProQuest Central, Medical and Scientific Publishers
CHF 1692.00 CHF 1946.00
WorldCat. Allschwilerstrasse 10
EUR 1524.00 EUR 1753.00
CH–4009 Basel
USD 1781.00 USD 2048.00
Publication Data: Dermatology is published 6 times Switzerland
a year. Volume 236 with 6 issues appears in 2020. postage and handling
t: +41 61 306 11 11
(added to print and print+online)
f: +41 61 306 12 34
Copyright: © 2020 S. Karger AG, Basel (Switzerland). CHF 52.80 Europe, CHF 74.40 Overseas
e: karger@karger.com
All rights reserved. No part of this publication may be EUR 48.00
w: www.karger.com
translated into other languages, reproduced or uti- USD 72.00
lized in any form or by any means, electronic or me- (for courier services only:
chanical, including photocopying, recording, micro- Allschwilerstrasse 10 Institutional subscription:
copying, or by any information storage and retrieval CH–4055 Basel)
Print or Online Print+Online combined
system, without permission in writing from the pub-
CHF 3501.00 CHF 4026.00
lisher. Change of Address:
EUR 3154.00 EUR 3627.00
Both old and new addresses should be sent
USD 3685.00 USD 4238.00
Disclaimer: The statements, opinions and data con- to the subscription source.
tained in this publication are solely those of the indi- postage and handling
vidual authors and contributors and not of the pub- (added to print and print+online)
lisher and the editor(s). The appearance of advertise- CHF 66.00 Europe, CHF 93.00 Overseas
ments in the journal is not a warranty, endorsement, EUR 60.00
or approval of the products or services advertised or USD 90.00
of their effectiveness, quality or safety. The publisher
and the editor(s) disclaim responsibility for any injury Back Volumes and Single Issues: Information on
to persons or property resulting from any ideas, availability and prices of single print issues and print
methods, instructions or products referred to in the or electronic back volumes can be obtained from
content or advertisements. Customer Service at service@karger.com.
© 2020 S. Karger AG, Basel
www.karger.com
karger@karger.comAdvances in facial rejuvenation
Dermal Fillers
Aesthetic Dermatology
Editor: D.J. Goldberg
Vol. 4
Dermal
Fillers Editor
Editor
D.J. Goldberg
David J. Goldberg
Dermal Fillers The aging process affects every aspect of the body, Contents
Editor: Goldberg, D.J. (New York, NY)
VI + 144 p., 66 fig., 62 in color, 7 tab., 2018
with the face being one of the first places to show
CHF 112.00 / EUR 105.00 / USD 132.00 signs. The search for the perfect injectable filler has • Preface: Goldberg, D.J.
Hard cover or online prices for personal taken an interesting path with the majority of innova- • History of Fillers: Narins, R.S.; Mariwalla, K.
customers
tions having been introduced in the last 30 years. The • Anatomy for Facial Fillers: The Skin Surface and
Prices subject to change, VAT not included
EUR price for eurozone countries, patient-driven demand for safe and effective mini- Beyond: Sykes, J.; Allak, A.; Palhazi, P.; Cotofana, S.
USD price for USA and Latin America only mally invasive aesthetic procedures has led to the • Neocollagenesis: Handler, M.Z.; Goldberg, D.J.
ISBN 978–3–318–06124–6
development of an expanding and competitive mar- • Hyaluronic Acid in Dermal Fillers: Goldie, K.;
e-ISBN 978–3–318–06125–3
ket for dermal fillers. The demand for soft tissue aug- Voropai, D.
Aesthetic Dermatology, Vol. 1–4 mentation has grown rapidly since its start in 1981 • Calcium Hydroxylapatite (Radiesse): Friedman, D.P.
Series Editor: Goldberg, D.J. (New York, NY) • Safe and Effective Injection Technique: Funt, D.K.
ISSN 2235–8609 / e-ISSN 2235–8595
with collagen fillers. Fillers using hyaluronic acid,
calcium hydroxyapatite, poly-L-lactic acid, and poly- • Novel Use of Fillers (Chin, Nose, Hands): Marmur, E.
Listed in MEDLINE/PubMed methylmethacrylate provide a wide range of options • Soft Tissue Augmentation in the US: Nestor, M.S.;
Bass, A.M.; Gold, M.H.
so that the best cosmetic outcome can be attained.
• Complications of Cosmetic Fillers: Grunebaum, L.D.;
The ability to correct facial rhytides and folds, to aug-
Funt, D.K.
ment lips and cheeks, to correct acne scars, and now
even to replenish volume loss in the dorsum of the Author Index / Subject Index
hands is something that many practitioners thought
would never be possible. This publication reviews the
history of fillers, injection techniques, complications
and safety as well as the novel use of fillers and fillers
of the future.
Dear Librarian
I have reviewed this publication and
would like to recommend it for our library.
Recommended by:
Department:
Date:
Signature: The easiest way to order: w w w.karger.com/aed
KI18111
Karger – Medical and Scientific Publishers
Orders may be placed with any bookshop, CH–4009 Basel, Switzerland
subscription agency, directly with the publisher orders@karger.com, f: +41 61 306 12 34
or through a Karger representative. www.karger.com28. JAHRESTAGUNG
Arbeitsgemeinschaft
Dermatologische Histologie
Dermatohistologie zwischen
Tradition und Moderne
Duisburg 15.–17. Mai 2020
www.adh-kongress.de
F20072
© Marcus Retkowietz - stock.adobe.com30th German Skin
Cancer Congress
DeCOG-Annual Meeting
09–12 September
2020
NUREMBERG
© 82041532 l Instantly l Fotolia.com
Annual Meeting of the Dermatologic Cooperative
Oncology Group (DeCOG)
of the German Cancer Society (DKG)
and the German Society of Dermatology (DDG)
F2005315th World Congress of the
International Academy of
Cosmetic Dermatology
© 232816660/3232816666/300299096 l Shevi • 301444949 l Paganin – shutterstock.com
18–20 June 2020 | Dresden | Germany
Progress meets (needs) Tradition
www.iacd2020.de
F20022FOBI 27. Fortbildungswoche
für praktische Dermatologie
2020 und Venerologie
MÜNCHEN
FORTSCHRITT durch FORTBILDUNG
07.07.2020 – 11.07.2020
Internationales Congress
Center München (ICM)
Neu in 2020:
kostenfreie Kurse Neues Team,
Praktisches Krankheitsmanagement neuer Termin,
bewährtes
What‘s new?
Plenarvorträge am Samstag in denen Konzept mit vielen
Ihnen kurz und bündig neue praxis- Neuerungen!
relevante Entwicklungen der letzten
2 Jahre aus 9 Themenbereichen von
der Ästhetischen Dermatologie bis zu
neuen topischen und systemischen
Therapien präsentiert werden www.fortbildungswoche.de
F19229The first dermatology journal
dedicated exclusively to case reports
www.karger.com/cde
• open access
Editor-in-Chief
• peer-reviewed
K.S. Ibler, Roskilde • fast online publication
Editorial Board This peer-reviewed online-only journal publishes original case reports
R. Antaya, G.B.E. Jemec, Roskilde
New Haven, CT L. Kemeny, Szeged covering the entire spectrum of dermatology, including prevention,
C. Berking, Munich J. Lademann, Berlin diagnosis, treatment, toxicities of therapy, supportive care, quality-of-
K.K. Clemmensen, R.A. Lee, La Jolla, CA life, and survivorship issues. The journal will also accept case reports
Copenhagen K. Matsunaga, Nagoya
F. Dalgard, Oslo M. Mogensen,
dealing with the use of novel technologies, both in the arena of diag-
F.W. Danby, Hanover, NH Copenhagen nosis and treatment. Supplementary material is welcomed.
M.A. de Rie, Amsterdam R. Na, Beijing The intent of the journal is to provide clinicians and researchers with
V. del Marmol, Brussels E.P. Prens, Rotterdam a tool to disseminate their personal experiences to a wider public as
L. Emtestam, Stockholm H. Riad Kottb, Doha
F. Furukawa, Wakayama T. Satoh, Tokorozawa, well as to review interesting cases encountered by colleagues all over
U. Gieler, Giessen T. Shiohara, Tokyo the world.
R. Gniadecki, Edmonton H.H. van der Zee, Universally used terms can be searched across the entire growing
D. Ioannides, Thessaloniki Rotterdam
P. Itin, Basel T. Yamamoto, Fukushima collection of case reports, further facilitating the retrieval of specific
information.
Following the open access principle, the entire contents can be re-
Case Reports in Dermatology trieved at no charge, guaranteeing easy access to this valuable source
Founded: 2009 of anecdotal information at all times.
Category: Clinical Research
Field of Interest: Dermatology
Listed in bibliographic services, including:
PubMed/PubMed Central, Web of Science,
Google Scholar, DOAJ, Scopus, Embase
2020: Vol. 12
3 issues per volume
online only
KF19016
Language: English
e-ISSN 1662–6567 More information at www.karger.com/cdeAn essential reference source
Adverse Reactions
Current Problems in Dermatology
Editors: P. Itin, G.B.E. Jemec
Vol. 53
Adverse Reactions
to Biologics
Editors
L. Puig
to Biologics
W. Gulliver
Editors
Lluís Puig
Wayne Gulliver
Adverse Reactions to Biologics In many areas of medicine physicians still face the Contents
Editors: Puig, L. (Barcelona); Gulliver, W.
great challenge of finding therapies that will meet
(St. John‘s) • Preface: Puig, L.; Gulliver, W.
X + 108 p., 25 fig., 24 in color, 12 tab., 2018 the patients’ needs. In dermatology the challenge has
• Introduction-Biologics in Dermatology:
CHF 139.00 / EUR 130.00 / USD 164.00 arisen on multiple fronts through advances in the
Hard cover or online prices for personal Indications and Off-Label Usage: Gulliver, W.; Puig, L.
understanding of the immunopathogenesis of many
customers • Adverse Reactions to Biologics in Psoriasis:
Prices subject to change, VAT not included inflammatory and malignant cutaneous disorders. Lockwood, S.J.; Prens, L.M.; Kimball, A.B.
EUR price for eurozone countries, Breakthroughs, combined with significant develop- • Clinical Trial and Registry Data: Gooderham, M.;
USD price for USA and Latin America only
ISBN 978–3–318–06100–0
ments in targeted immunotherapy, have resulted in Papp, K.
e-ISBN 978–3–318–06101–7 improved outcomes as these newer therapies are • Immunosuppression/Infections across Indications:
being used for both approved indications and as off- Al-Khalili, A.; Dutz, J.P.
Current Problems in Dermatology, Vol. 53
Series Editors: Itin, P. (Basel), Jemec, G.B.E.
label therapies for various chronic inflammatory skin • The Immunogenicity of Biologic Therapies:
(Roskilde) disorders and many forms of skin cancer. Garcês, S.; Demengeot, J.
ISSN 1421–5721 / e-ISSN 1662–2944 In the expectation that by truly understanding the • Paradoxical Reactions: Anti-Tumor Necrosis Factor
Listed in MEDLINE/PubMed
safety profile of these targeted therapies patients’ Alpha Agents, Ustekinumab, Secukinumab,
outcomes will be significantly improved, this book Ixekizumab, and Others: Puig, L.
offers insights into topics such as adverse reactions, • Bullous Diseases: Corbaux, C.; Joly, P.
infectious complications and the perioperative use • Adverse Reactions of Antibody-Therapy for
of biologics in psoriasis, immunogenicity of biologic Primary Cutaneous Lymphomas: Rituximab,
therapies, paradoxical reactions, safety of biologics Brentuximab Vedotin, Alemtuzumab, and
used to treat psoriasis, autoimmune bullous diseases Mogamulizumab: Saulite, I.; Guenova, E.;
and primary cutaneous lymphomas, adverse reac- Hoetzenecker, W.
tions and skin manifestations of therapies targeting • Adverse Reactions to Biologics: Melanoma
melanoma and non-melanoma skin cancer and (Ipilimumab, Nivolumab, Pembrolizumab):
Hwang, S.J.E.; Fernández-Peñas, P.
other neoplastic diseases.
• Skin Manifestations of Targeted Antineoplastic
Eminent researchers with extensive clinical experi-
ence have contributed to this publication, providing Therapy: Sanmartín, O.
an in-depth overview of the latest knowledge in this Author Index / Subject Index
field.
Dear Librarian
I have reviewed this publication and
would like to recommend it for our library.
Recommended by:
Department:
Date:
Signature: The easiest way to order: w w w.karger.com/cpd
KI18109
Karger – Medical and Scientific Publishers
Orders may be placed with any bookshop, CH–4009 Basel, Switzerland
subscription agency, directly with the publisher orders@karger.com, f: +41 61 306 12 34
or through a Karger representative. www.karger.comThe venue for research on new drugs and therapeutic concepts
Journal of Pharmacological and Biophysical Research
Journal of Pharmacological and Biophysical Research
Editor Associate Editors M. Roberts,
J. Lademann, Berlin P. Elias, Brisbane, QLD
San Francisco, CA C. Surber, Basel
Honorary Editor J.W. Fluhr, Berlin P. van de Kerkhof,
H.F. Merk, Aachen H.I. Maibach, Nijmegen
San Francisco, CA
H. Mukhtar,
Madison, WI
Official Organ of the
Society for Dermopharmacy
In the past decade research into skin pharmacology has rapidly devel- Selected contributions
oped with new and promising drugs and therapeutic concepts being • Commentary on the “Evidence- and Consensus-Based (S3) Guidelines
introduced regularly. Recently, the use of nanoparticles for drug delivery for the Treatment of Actinic Keratosis” Published by the lnternational
in dermatology and cosmetology has become a topic of intensive re- League of Dermatological Societies in Cooperation with the European
search, yielding remarkable and in part surprising results. Another Dermatology Forum: Diepgen, T.L. (Heidelberg); Kresken, J. (Viersen);
Krutmann, J. (Düsseldorf ); et al.
topic of current research is the use of tissue tolerable plasma in wound
• Vitamin D and the Pathophysiology of lnflammatory Skin Diseases:
treatment. Stimulating not only wound healing processes but also the Umar, M.; Sastry, K.S.; Al Ali, F.; Al-Khulaifi, M.; Wang, E.; Chouchane, A.l.
penetration of topically applied substances into the skin, this novel (Doha)
technique is expected to deliver very interesting results. • A Time-Series Study of the Effect of Air Pollution on Outpatient Visits for
There are many open questions which reflect the importance of the Acne Vulgaris in Beijing: Liu W.; Pan X. (Beijing); Vierkötter A. (Düsseldorf ); et al.
subject and the need for an international scientific forum where they • Laser Scanning Microscopic Investigations of the Decontamination of
can be discussed in extenso. Dermatologists, pharmaceutical chemists, Soot Nanoparticles from the Skin: Lademann, J.; Knorr, F.; Patzelt, A.;
pharmacologists, toxicologists, and others interested in the subject are Meinke, M.C.; Richter, H.; Krutmann, J.; Rühl, E.; Doucet, O. (Berlin)
invited to contribute and to submit their best research work for publica- • The Influence of Reactive Oxygen Species and Glucocorticoids on Dry
tion in Skin Pharmacology and Physiology. Skin in a Mouse Model of Arthritis: Goto, K.; Hiramoto, K.; Kawakita, M.;
Yamaoka, M.; Ooi, K. (Suzuka)
• Physiological and Molecular Effects of in vivo and ex vivo Mild Skin
Skin Pharmacology and Physiology Barrier Disruption: Pfannes, E.K.B.; Weiss, L.; Hadam, S. (Berlin); et al.
Founded: 1988 • Effects of Short-Term Moisturizer Application in Different Ethnic Skin
Category: Clinical and Basic Research Types: Noninvasive Assessment with Optical Coherence Tomography
Fields of Interest: Pharmacology, Dermatology and Reflectance Confocal Microscopy: Bağcı, I.S.; Ruini, C.; Niesert, A.-C.;
Horváth, O.N.; Berking, C.; Ruzicka, T.; von Braunmühl, T. (Munich)
Listed in bibliographic services, including: • Development and Evaluation of Lipid Nanoparticles Containing Natural
PubMed/MEDLINE, Web of Science, Botanical Oil for Sun Protection: Characterization and in vitro and in vivo
Google Scholar, Scopus, Embase Human Skin Permeation and Toxicity: Andréo-Filho, N.; Bim, A.V.K;
2019: Volume 32 Kaneko, T.M (São Paulo); et al.
6 issues per volume
Language: English
ISSN 1660–5527
e-ISSN 1660–5535
KF 19105
Impact Factor: 1.974
More information at w w w. karger.com/sppwww.karger.com/drm
236 | 1 | 20
Hidradenitis Suppurativa:
A Challenging Disease
Challenges and Perspectives
Hidradenitis suppurativa (HS) is a chronic inflammatory skin condi-
tion characterized by relapsing abscesses, nodules, and suppurat-
ing lesions mainly located in the intertriginous areas of the skin.
Although data coming from epidemiological studies are divergent,
it is suggested that the disease may affect up to 1% of the general
population. The complex nature of HS constitutes a real challenge
for clinicians in terms of making an appropriate diagnosis, assess-
ing the disease severity and deciding on a suitable therapeutic ap-
proach.
This special issue covers current relevant topics around the man-
agement of HS.
Cover illustration
For details see Vol. 236, No. 1, 2020, p. 48 , Fig. 2.You can also read
