PATIENT-CENTRIC CARE DRIVES HEALTHCARE IT AND TELEHEALTH MARKETS - HEALTHCARE IT INDUSTRY UPDATE | MAY 2021

 
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PATIENT-CENTRIC CARE DRIVES HEALTHCARE IT AND TELEHEALTH MARKETS - HEALTHCARE IT INDUSTRY UPDATE | MAY 2021
PATIENT-CENTRIC CARE DRIVES HEALTHCARE IT
AND TELEHEALTH MARKETS
HEALTHCARE IT INDUSTRY UPDATE | MAY 2021

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PATIENT-CENTRIC CARE DRIVES HEALTHCARE IT AND TELEHEALTH MARKETS - HEALTHCARE IT INDUSTRY UPDATE | MAY 2021
TABLE OF CONTENTS
       Key Industry Takeaways       4
       Industry Outlook             5
       Key Trends & Drivers         6
       Enterprise Activity           7
       M&A Overview                 8
       Notable Transactions         9
       Select Transactions          10
       Buyer Universe               12
       Financing Activity           13
       Public Company Data          14
       Report Contributors          15
       Firm Track Record            16
       Endnotes                     17

CONTACT OUR HEALTHCARE IT
INDUSTRY EXPERTS

            David DeSimone
            Managing Director
            617-619-3324
            ddesimone@capstonepartners.com

            David Michaels
            Managing Director
            Head of TMT Practice
            858-926-5950
            dmichaels@capstonepartners.com
PATIENT-CENTRIC CARE DRIVES HEALTHCARE IT AND TELEHEALTH MARKETS - HEALTHCARE IT INDUSTRY UPDATE | MAY 2021
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PATIENT-CENTRIC CARE DRIVES HEALTHCARE IT AND TELEHEALTH MARKETS - HEALTHCARE IT INDUSTRY UPDATE | MAY 2021
Healthcare IT Industry
Patient-centric Care Drives HCIT & Telehealth Markets

KEY INDUSTRY TAKEAWAYS

Capstone Partners’ Technology, Media, and Telecom (TMT) Group is pleased to share its Healthcare
Information Technology (HCIT) report. Through our analysis of emerging enterprises in the space and the
evolution of virtual care, we have identified several key takeaways below, followed by an in-depth overview of
industry dynamics on the following pages.

   1.   HCIT transformed the Healthcare industry amid COVID-19, enabling patients and providers to connect
        through online platforms for virtual consults, medication delivery, and health record documentation.

   2.   Healthcare providers increasingly invested in cloud infrastructure and artificial intelligence to bolster
        IT bandwidth and workflow automation enterprise-wide.

   3.   The entrance of non-traditional players in the HCIT industry has created a heavily fragmented market,
        with enterprises extending telehealth offerings beyond employees and their families.

   4. Strategic and private equity buyers in the sector are well-capitalized and increasingly focused on
      acquiring targets with proprietary platforms to propel growth in 2021.

   5.   Venture capital funding reached record levels in 2020, with investors shifting focus to sector-specific
        providers and larger funding transactions.

Capstone Partners has developed a full suite of corporate finance solutions, including M&A advisory, debt
advisory, financial advisory, and equity capital financing to help privately owned businesses and private equity
firms through each stage of the company’s lifecycle, ranging from growth to an ultimate exit transaction.

To learn more about Capstone’s wide range of advisory services and Healthcare IT industry expertise, please
contact Capstone Managing Director David DeSimone.

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PATIENT-CENTRIC CARE DRIVES HEALTHCARE IT AND TELEHEALTH MARKETS - HEALTHCARE IT INDUSTRY UPDATE | MAY 2021
Healthcare IT | May 2021

    INDUSTRY OUTLOOK

  Healthcare information technology (HCIT) played a
  key role in the transformation of the Healthcare
                                                                                                    Five Stages for Healthcare Institutions
  industry in 2020, with elevated demand for virtual
  care offerings and streamlined processes
  instituted across modalities. As a result, the                                                      1.   Resolve: Industry players, including
  Healthcare industry underwent five stages of                                                             governments and providers,
  evolution (resolve, resilience, return, reimagination,                                                   determined the scale, pace, and depth
  and reform) to combat COVID-19 through digital                                                           of the action necessary to address
  solutions, according to McKinsey & Company.1                                                             COVID-19.
  With the rollout of COVID-19 vaccines in 2021, HCIT
                                                                                                      2.   Resilience: Healthcare institutes and
  companies have partnered with manufacturers to
                                                                                                           business leaders prepared for the
  track the effectiveness and distribution among
                                                                                                           rapid succession of financial
  eligible participants. For example, China’s leading
                                                                                                           challenges including liquidity,
  healthcare community platform DXY partnered
                                                                                                           solvency, and profitability hurdles.
  with vaccine manufacturer Pfizer (NYSE:PFE) to
  provide accessible vaccination records.                                                             3.   Return: Returned businesses to
                                                                                                           operational health amid shutdowns
  Telehealth companies have expanded to provide                                                            and continued to provide care to
  additional digital capabilities such as prescription                                                     patients with time-sensitive or
  delivery and remote monitoring. Notably, 57% of                                                          immediate needs.
  consumers are open to in-home care and remote
  monitoring through wearable devices, according to                                                   4.   Reimagination: Technological
  Accenture.2 Publicly traded telehealth companies                                                         solutions were heavily adopted to
  recorded a total return of +77.7% from January 1,                                                        provide telehealth services,
  2020 to May 17, 2021, outpacing the Nasdaq and                                                           prescription delivery services, and
  broader HCIT market. Public players experienced a                                                        manage remote operations.
  surge in annual revenue, led by Teledoc Health’s
  (NYSE:TDOC) 145% increase in revenue in 2020                                                        5.   Reform: Industry participants
  ($1.1 billion) compared to the 2019 ($553.3 million),                                                    continue to shift business models to
  according to its Q4 2020 earnings call.3                                                                 integrate IT solutions, elevating the
                                                                                                           accessibility of health services with a
  Strong industry tailwinds and the innovations                                                            focus on patient-centric care.
  outlined on the following pages have led to record
  levels of venture capital investments and
                                                                                                                                       Source: McKinsey & Company
  heightened merger and acquisition (M&A) activity
  in 2020 and 2021 year-to-date (YTD).

                                            Capstone Telehealth Index Outpaces HCIT Index & Nasdaq
                                          Capstone Telehealth Index                    Capstone HCIT Index                     Nasdaq Composite Index
Index Value Percent Change

                             400%

                             300%

                             200%
                                                                                                                                                          +77.7%
                             100%

                               0%

                             -100%
                                 Jan-20   Mar-20      May-20           Jul-20          Sep-20          Nov-20           Jan-21         Mar-21          May-21
                                                                                                        Source: Capital IQ and Capstone Research as of May 17, 2021
                                                                                                          Telehealth Index Includes: AMWL, HIMS, LFMD, OTRK, TDOC
                                             HCIT Index Includes: ACCD, MDRX, ASCN, BNFT, CSLT, CERN, CHNG, EVH, HSTM, GOCO, INOV, OMCL, ONEM, PINC, VCRA, IQV

                                                                                                                                                                      5
PATIENT-CENTRIC CARE DRIVES HEALTHCARE IT AND TELEHEALTH MARKETS - HEALTHCARE IT INDUSTRY UPDATE | MAY 2021
Healthcare IT | May 2021

   KEY TRENDS & DRIVERS

    18.1%                                  ANNUAL GROWTH FOR HCIT
                                           CLOUD INFRASTRUCTURE
                                                                                          Digital front door systems originated with Zipnosis,
                                                                                          Inc., developer of an automated virtual care
                                                                                          platform to maximize clinician’s time and provide
    HCIT industry participants combated elevated                                          patients with a greater choice of care. Zipnosis’s
    production challenges at the height of the                                            Digital Front Door® is designed for third-party
    pandemic, driven by significant supply chain                                          healthcare providers as a platform to increase
    disruptions. Demand for HCIT hardware including                                       patient access and reduce clinical burnout.
    laptops, tablets, mobile devices, and computer
    chips substantially outpaced supply, which led to                                     The entrance of non-traditional players in the HCIT
    the refurbishment of existing systems for remote                                      industry has created a heavily fragmented market.
    work. Funds reserved for new hardware were                                            Enterprises     have    disrupted     the   already
    repurposed by organizations to support revenue                                        competitive market with a range of consumer-
    disruptions, contingency plans, and to invest in                                      focused healthcare services including prescription
    cloud infrastructure.                                                                 delivery, virtual consultations, and in-home visits.
                                                                                          Although the offerings were originally introduced
    The increase in data collected by industry players                                    to employees, enterprises have expanded to serve
    from remote care, electronic health records, and                                      the broader market (see page seven).
    prescription information propelled the adoption of
    cloud infrastructure to effectively manage the
    large volume of data and increase IT bandwidth.
    With this shift, the Global Healthcare IT Cloud
                                                                                          44%            OF HEALTHCARE LEADERS
                                                                                                         INCREASED AI INVESTMENT
    market is expected to reach $64.7 billion by 2025                                     Healthcare providers have experienced workflow
    with a compound annual growth rate (CAGR) of                                          and processing challenges as COVID-19 exposed
    18.1%, according to Markets and Markets.4                                             weaknesses in providers’ data intelligence.
                                                                                          Historically, artificial intelligence (AI) automation
                                 Global Healthcare IT Cloud Market                        tools have been used in the Healthcare industry
                     $100                                                                 for specific use cases. During COVID-19 44% of
                                                                                          healthcare leaders reported an increase in AI
U.S. Dollars in Billions

                           $80                                                            investments enterprise-wide to enhance clinical
                                                                              $64.7       decision-making regarding virtual care, according
                           $60                                       $54.7
                                                            $46.3                         to the Center for Connected Medicine.6 AI tools
                                                    $39.2                                 providing operational efficiency are also in high
                           $40              $33.2
                                   $28.1                                                  demand as healthcare facilities track remote
                                                                                          patient utilization and manage revenue cycles.
                           $20
                                                                                          Notably, Microsoft Azure collaborated with UC San
                           $0                                                             Francisco's Center for Digital Health Innovation
                                   2020     2021    2022    2023     2024     2025        (CDHI), Fortanix, and Intel to establish CDHI’s
                                                                                          BeeKeeper AI, a platform generating a clinical
                                                            Source: Markets and Markets
                                                                                          algorithm to bolster confidential data access.7

    70%                                    OF PATIENTS PREFER DIGITAL
                                           FRONT DOOR HEALTH SYSTEMS
                                                                                                Effects of COVID-19 on AI Investment

                                                                                                                                             3%
    COVID-19 has presented a paradigm shift in the                                                                                  9%
    HCIT industry, with providers increasing focus on                                        Decreased Investment
    patient-centric solutions, particularly digital front                                    Unsure                    44%
    door systems. With 70% of patients preferring                                            No Impact
    consolidated digital health solutions, digital front                                     Increased Investment
                                                                                                                                          44%
    door systems provide a variety of telehealth and
    telemedicine offerings on a single platform
    allowing consumers to select specific providers,
    according to L&T’s Digital Front Door Survey.5                                                                Source: Center for Connected Medicine

                                                                                                                                                          6
PATIENT-CENTRIC CARE DRIVES HEALTHCARE IT AND TELEHEALTH MARKETS - HEALTHCARE IT INDUSTRY UPDATE | MAY 2021
Healthcare IT | May 2021

ENTERPRISE ACTIVITY

In response to COVID-19 and the need for prompt digital health solutions, many leading companies have
focused on launching or expanding virtual health solutions for their customers and employees. Select
enterprises and their growth initiatives are outlined below.

                                        Amazon.com, Inc. (Nasdaq:AMZN) launched Amazon Care 18 months ago
                                        to provide Amazon employees and their families access to medical care
                                        through its proprietary platform. The service allows employees to
                                        connect with medical professionals through an online chat forum or
                                        video conferencing. The Amazon Care application (app) connects its
                                        employees directly with nurses and doctors via in-app messaging or
                                        video. Amazon Care also operates as a digital front door, dispatching
Founded: 1994                           medical professionals to a patient’s home and delivering prescriptions.
Ownership: Publicly Traded (NAS:AMZN)
Stock Price as of 5/17/21: $3,222.90    As of March 2021, Amazon expanded Amazon Care to provide virtual
Headquarters: Seattle, WA               health services to all Amazon employees in the U.S. and other
FY 2020 Revenue: $386.1 Billion
                                        Washington-based companies, according to a press release.8

                                        CVS Health Corp. (NYSE:CVS) through its subsidiary, CVS Caremark,
                                        operates a digital health platform specializing in prescription benefit
                                        management (PBM). For consumers, the platform enables patients to
                                        order prescriptions online or via mobile app, in addition to checking
                                        prices and processing digital payments.

                                        CVS also provides a Point Solutions Management platform for health
Founded: 1963                           plan sponsors to manage and contract third-party digital health tools.
Ownership: Publicly Traded (NYSE:CVS)   Launched in 2019, CVS has grown the platform by adding specialized
Stock Price as of 5/17/21: $84.33       health applications to its database. Notably, Hinge Health, Hello Heart,
Headquarters: Woonsocket, RI
                                        Livongo, Torchlight, and Whil were added to the platform in March 2021,
FY 2020 Revenue: $268.0 Billion
                                        as stated in a press release.9

                                        Walmart Inc. (NYSE:WMT) partnered with Doctor on Demand, Inc. in
                                        January 2020 to provide telehealth services to its employees and their
                                        families through a Walmart-operated portal. At the start of COVID-19,
                                        Walmart opened its platform to enable customers to access virtual
                                        health consultations from Doctor on Demand’s medical professionals.
                                        Additionally, Walmart announced its initiative to provide customers
                                        access to their electronic health records in March, beginning with
Founded: 1962                           COVID-19 vaccine records, according to a press release.10
Ownership: Publicly Traded (NYSE:WMT)
Stock Price as of 5/17/21: $139.52      Furthermore, Walmart enhanced the digital capabilities of its
Headquarters: Bentonville, AR           pharmacies with the acquisition of CareZone, developer of a healthcare
FY 2020 Revenue: $524.0 Billion
                                        platform to streamline pharmacy delivery services (June, $200 million).

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PATIENT-CENTRIC CARE DRIVES HEALTHCARE IT AND TELEHEALTH MARKETS - HEALTHCARE IT INDUSTRY UPDATE | MAY 2021
Healthcare IT | May 2021

M&A OVERVIEW

Demand in the HCIT industry accelerated in 2020                                             Healthcare IT M&A Volume
as COVID-19 forced healthcare providers to adapt
to remote care. This has been reflected in
                                                                                 400
heightened M&A activity in 2020, increasing 36%
year-over-year (YOY) and outpacing 2019 in each                                  350

                                                        Number of Transactions
quarter, reaching a total of 293 transactions.                                                                          293
                                                                                 300
Following record levels in Q1 2020, deal volume
dipped in Q2 and Q3 as top healthcare providers                                  250                           216
focused internally to defend revenues and mitigate                                         184       195
                                                                                 200
risk attributed to delayed elective procedures and
                                                                                                                                             141
non-urgent healthcare visits. With the adoption of                               150                                               117
software services and telehealth, transaction
                                                                                 100
volume rebounded in Q4, resulting in an increase
of 27% quarter-over-quarter (76 deals). M&A                                       50
activity has continued to thrive in 2021 YTD, with
                                                                                   0
141 deals announced or completed as strategic and
private equity (PE) buyers identified HCIT’s                                              2017      2018      2019     2020 YTD '20 YTD '21
indisputable impact on          the distribution and
accessibility    of    digitally-based     healthcare
products and services.

Strategic buyers accounted for ~61% of
transactions in 2020, as HCIT companies sought
synergistic opportunities to integrate additional                                              2020 Buyer Breakdown
capabilities within existing frameworks. Notably,
Hinge Health, Inc. announced its acquisition of
Thimble Bioelectronics, Inc. to amalgamate                                        STRATEGIC                                     15.7%
Thimble’s wearable pain relief sensor and mobile                                     Public                       32.5%
application with Hinge Health’s application for                                      Private
tracking chronic pain levels (March, undisclosed).
PE add-on acquisitions represented 33% of deals                                   FINANCIAL
in 2020 and 37% in 2021 YTD, outpacing the                                           Platform
greater Healthcare market as firms looked to                                         Add-on                                       45.7%
                                                                                                           6.1%
efficiently bolster digital health offerings for
existing portfolio companies. Of note, The Carlyle
Group-backed Grand Rounds Inc. announced its
merger with Doctor on Demand, Inc. to create a
combined entity providing telehealth and patient                                                                    Year-to-date (YTD) ended May 17
advocacy tools (March, undisclosed).                                                   Source: Capital IQ, PitchBook, FactSet, and Capstone Research

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PATIENT-CENTRIC CARE DRIVES HEALTHCARE IT AND TELEHEALTH MARKETS - HEALTHCARE IT INDUSTRY UPDATE | MAY 2021
Healthcare IT | May 2021

NOTABLE TRANSACTIONS

               Optum, Inc. to Acquire Change Healthcare, Inc.
               (January 2021, $13.5 Billion, 5.6x Revenue)

               UnitedHealth Group’s (NYSE:UNH) Optum, Inc., developer of a health care system
               designed to connect patients and providers across the healthcare ecosystem,
               announced its acquisition of Change Healthcare, Inc. (Nasdaq:CHNG) in January for $13.5
               billion (equivalent to 5.6x revenue). Change Healthcare provides software, data analytics,
               research, revenue cycle management, and technology-enabled services for the
               Healthcare industry. Following Optum’s acquisition of AbleTo in the Telehealth market,
  To Acquire   this acquisition will bolster Optum’s clinical-analytics capabilities and technology to
               integrate evidenced-based criteria into clinician workflow management and optimize in-
               person and virtual visits.

               “This opportunity is about advancing connectivity and accelerating innovations and
               efficiencies essential to a simpler, more intelligent and adaptive health system,”
               commented Neil de Crescenzo, CEO of Change Healthcare, and future CEO of
               OptumInsights, according to a press release.11 The deal exemplifies the larger movement
               of consolidation to improve patient outcomes and reduce costs.

               WELL Health Technologies Corp. Announced Three Acquisitions in Q1 2021

               WELL Health Technologies Corp. (TSX:WELL), owner and operator of a portfolio of primary
               health clinics delivering clinical, electronic medical record, and digital health services,
               announced or completed six acquisitions in Q4 2020 and three in Q1 2021. WELL Health
               attributed its 51% total annual revenue increase in 2020 ($50.2 million) to the acquisitions
               made over the past year, specifically highlighting the software and telehealth revenue
               increase of 393% for the year ($12.3 million) in its investor presentation.12 Summarized
  To Acquire   below are WELL Health’s three acquisition targets in Q1 2020.

               • Intrahealth Systems Limited (March 2021, $15.2 Million) - Intrahealth Systems
                 Limited, developer of medical software solutions, entered into a definitive
                 agreement to be acquired by WELL Health in March for an enterprise value of
                 $15.2 million. Based in Auckland, New Zealand, Intrahealth’s software platform
                 supports mobile care, virtual care, and telehealth solutions, serving hospitals,
                 public health outpatient centers, and home care providers.
      &
               • CRH Medical Corp. (February 2021, $426.2 Million) - WELL Health announced
                 their acquisition of CRH Medical Corp. (TSX:CRH), a healthcare products and
                 services company, for an enterprise vale of $426.2 million in February. CRH
                 utilizes its proprietary platform, CRH O’Regan System, to distribute, market,
                 and track services directly to gastroenterologists. The company specializes
      &
                 in single-use, disposable hemorrhoid treatment in the U.S. and Canada.

               • Open Health Software Solutions, Inc. (January 2021, Undisclosed): WELL
                 Health acquired Open Health Software Solutions, Inc. in January for an
                 undisclosed sum. Open Health provides services for installing and supporting
                 affordable software and hardware for the healthcare community. Its services
                 include software assessment, readiness assessment, and electronic medical
                 record integration and adoption.

                                                                                                              9
Healthcare IT | May 2021

SELECT TRANSACTIONS

                                                                                                                   Enterprise           EV / LTM
Date       Target                Acquirer              Target Business Description                                 Value (mm)       Revenue EBITDA

           d-Wise                                      Provides software solutions and IT consulting services
03/22/21                         Instem (AIM:INS)                                                                       $31.0            -            -
           Technologies                                to Healthcare and Life Sciences industry.

                                                       Develops an online platform allowing patients to consult
03/16/21   Doctor on Demand      Grand Round                                                                              -              -            -
                                                       doctors and healthcare providers.

           Cumberland                                  Offers healthcare consulting services to implement
03/16/21                         Tegria                                                                                   -              -            -
           Consulting                                  technologies to maximize operational efficiency.

                                 Compel Capital        Provides COVID-19 digital passport medical services
03/11/21   GoStop                                                                                                         -              -            -
                                 (CNSX:SCRN)           through a digital medical passport.

                                                       Develops software products and IT solutions to help
03/09/21   Bio-Optronics         Advarra                                                                                  -              -            -
                                                       healthcare professionals in optimizing workflow.

                                                       Provides a platform that automates patient care
03/09/21   Karuna Health         Commure                                                                                  -              -            -
                                                       management tasks for hospitals.

           Thimble                                     Develops wearable devices and applications that tracks
03/09/21                         Hinge Health                                                                             -              -            -
           Bioelectronics                              patient progress towards reducing pain.

                                 WELL Health Tech.     Provides electronic medical records (EMR) and clinical
03/08/21   Intrahealth Systems                                                                                          $15.2            -            -
                                 (TSX:WELL)            healthcare software solutions.

                                                       Designs and develops electronic health records and
03/04/21   Bizmatics             N. Harris Computer                                                                       -              -            -
                                                       health practice management software.

03/03/21   BlipIQ                BioIQ                 Provides SaaS-based telehealth to healthcare providers.            -              -            -

                                                       Provides online and on-demand telehealth delivery
02/26/21   MDLIVE                Evernorth                                                                                -              -            -
                                                       services and software.

           HGE Health Care       Vapotherm             Develops a clinical services platform enabling providers
02/24/21                                                                                                               $24.5             -            -
           Solutions             (NYSE:VAPO)           and patients to track day-to-day symptoms.

                                 Mind Medicine         Provides an artificial intelligence based digital
02/18/21   Healthmode                                                                                                  $33.2             -            -
                                 (OTCPK:MMED.F)        measurement solutions for medicine and clinical trials.

                                                       Offers SaaS-based track and trace solutions for the
02/16/21   rfxcel                Antares Vision                                                                        $150.0           8.8x          -
                                                       pharmaceutical supply chain.

                                 Nuance Comm.          Designs and develops a mobile AI assistant to automate
02/08/21   SayKara                                                                                                        -              -            -
                                 (NAS:NUAN)            clinical documentation for physicians.

                                                       Provides a platform that provides health information for
02/03/21   Lab Tests Online      OneCare Media                                                                            -              -            -
                                                       patients, caregivers, and medical professionals.

           Park Place                                  Offers healthcare information technology (IT) solutions
02/01/21                         ABRY Partners                                                                            -              -            -
           International                               including cloud and IT infrastructure solutions.

                                                       Develops and offers software and mobile applications to
01/28/21   Docent Health         GetWellNetwork                                                                           -              -            -
                                                       organize and monitor patient care.

           Preventice            Boston Scientific     Provides healthcare solutions by utilizing portfolio of
01/21/21                                                                                                               $1,153.1         7.3x          -
           Solutions             (NYSE:BSX)            services, sensors, and software.

           Discovery Health      MultiPlan             Offers cloud-based healthcare cost solutions to
01/21/21                                                                                                               $155.0            -            -
           Partners              (NYSE:MPLN)           healthcare providers and payers.

           Capsule               Koninklijke Philips   Provides device connectivity solutions that enable
01/19/21                                                                                                               $635.0           6.4x          -
           Technologies          (ENXTAM:PHIA)         medical device manufacturers to deliver wireless health.

                                                       Offers patient-centric telehealth engagement and
01/19/21   TouchPointCare        CareXM                                                                                   -              -            -
                                                       monitoring solutions for healthcare providers.

                                 Beyond Medical        Develops an artificial intelligence-based healthcare
01/14/21   Kayan Health                                                                                                   -              -            -
                                 (OTCPK:DOCK.F)        platform for streamlining communications.

                                                                                                 Source: Capital IQ, PitchBook, FactSet, and Capstone Research

                                                                                                                                                                 10
Healthcare IT | May 2021

SELECT TRANSACTIONS (CONTINUED)

                                                                                                                 Enterprise          EV / LTM
Date       Target              Acquirer              Target Business Description                                 Value (mm)      Revenue EBITDA

           Innovation          Accolade              Provides medical video consultation services for
01/14/21                                                                                                            $433.8          12.4x          -
           Specialists         (NAS:ACCD)            physicians and patients.

                                                     Offers an application to simplify the healthcare provider
01/13/21   Avhana Health       Amalgam Rx                                                                              -              -            -
                                                     workflow integrated with their EHR.

                               Advanced Medical      Develops an application that allows members to shop
01/12/21   Drexi                                                                                                       -              -            -
                               Pricing Solutions     for the lowest priced prescriptions in their area.

           Mavens                                    Designs, builds, and implements software used by
01/11/21                       Komodo Health                                                                           -              -            -
           Consulting                                healthcare professionals, patients, and consumers.

           Change Healthcare                         Provides data analytics solutions to enhance patient
01/06/21                       Optum                                                                               $13,547.9        5.6x           -
           (NAS:CHNG)                                engagement in the healthcare system.

                                                     Develops a healthcare communication platform for
12/24/20   Updox               EverCommerce                                                                            -              -            -
                                                     records sharing and virtual care for patients.

           Tenet Healthcare                          Provides a health care platform for urgent care needs.
12/18/20                       FastMed Urgent Care                                                                  $80.0             -            -
           (NYSE:THC)

                               WELL Health Tech.     Develops a cloud-based software, which provides
12/17/20   Adracare                                                                                                    -              -            -
                               (TSX:WELL)            services for managing electronic health records.

           Highmark            Stormcrow             Provides software development services for health care
12/11/20                                                                                                             $12.9            -            -
           Innovations         (TSXV:CROW.P)         providers including medical diagnostics.

           myClinical          HealthStream          Develops a SaaS application that allows healthcare
12/10/20                                                                                                               -              -            -
           Exchange            (NAS:HSTM)            organizations to track rotations of healthcare staff.

           Comprehensive                         Offers a healthcare administrative software for the
12/09/20                      Greenstone Capital                                                                       -              -            -
           Healthcare Systems                    healthcare industry.

                                                     Designs artificial intelligence-based prior authorization
12/03/20   Verata Health       Olive AI                                                                             $120.0            -            -
                                                     process software solutions for healthcare providers.

                                                     Provides a virtual care management (VCM) platform for
11/30/20   VirTrial            Signant Health                                                                          -              -            -
                                                     the health care industry.

                               CompuGROUP            Offers integrated HER and digital management solutions
11/23/20   e-MDs                                                                                                   $240.0            2.7x        18.2x
                               Holding               for physician practices and enterprises.

           Cloudbreak          GigCapital2
11/23/20                                             Provides telehealth and language access services.              $139.0            -            -
           Health              (NYSE:GIX)

           Health Care         Carebook Tech.        Develops a health navigation platform software for
11/19/20                                                                                                             $11.5           3.3x          -
           Services Intl.      (TSXV:CRBK)           healthcare organizations and individuals.

                               WELL Health Tech.     Offers an online telehealth platform which connects
11/09/20   INSIG                                                                                                    $36.3             -            -
                               (TSX:WELL)            patients with healthcare providers.

                               Grifols Shared        Provides Web and handheld-based software solutions
11/09/20   Goetech                                                                                                  $122.9            -            -
                               Services              to hospitals and retail pharmacies.

                               WELL Health Tech.
11/02/20   DoctorCare                                Develops billing and optimization software for doctors.         $13.5           5.1x        17.0x
                               (TSX:WELL)

           Medical             CloudMD               Provides a health care navigation platform which
10/22/20                                                                                                             $5.1            3.3x          -
           Confidence          (TSXV:DOC)            connects individuals with health care providers.

           Canadian Medical    CloudMD               Offers an online directory of profile and contact
10/21/20                                                                                                               -              -            -
           Directory           (TSXV:DOC)            information on physicians and nurse practitioners

                                                     Develops care coordination software solutions to
10/13/20   CarePort Health     WellSky                                                                             $1,350.0         13.0x        21.0x
                                                     manage patient transitions.

                               HealthStream          Designs and develops healthcare workforce
10/12/20   ShiftWizard                                                                                              $32.0             -            -
                               (NAS:HSTM)            management software solutions.

                                                                                              Source: Capital IQ, PitchBook, FactSet, and Capstone Research

                                                                                                                                                              11
Healthcare IT | May 2021

BUYER UNIVERSE

Capstone has built relationships with and tracked buyers that have been highly acquisitive in the Healthcare IT
industry, particularly those that have completed notable HCIT transactions. Our industry expertise and network
provides us with unique insights into this buyer universe and industry and growth drivers for the companies
within it.

                                        Leading Strategic Buyers

                                        Leading Financial Buyers

                                                                                           Source: Capstone Research

                                                                                                                       12
Healthcare IT | May 2021

   FINANCING ACTIVITY

 Patient-driven care has heightened demand in the HCIT industry as providers have adapted to the remote
 healthcare environment. Emerging startup companies and enterprises expanding digital capabilities saw a rise in
 venture capital funding among HCIT providers, with total funding setting an annual record of $14.1 billion in 2020,
 an increase of 93% YOY. Total venture capital transaction volume experienced an uptick of only 1% in 2020 (1,449
 deals) YOY, as investors focused on sector-specific providers and much larger funding transactions. Total
 venture capital funding and deal volume in Q1 2021 has been on pace with the prior quarter. Highlighted below
 are several notable venture funding deals from Q1 2021 and Q4 2020.

                                                       Healthcare IT Venture Capital Raises
                                                                  (2010 – 2020)
                                                                Total Volume       Total Value

                         2,000                                                                                                     $20.0
Number of Transactions

                         1,750
                                                                                                                        $14.1

                                                                                                                                           U.S. Dollars in Billions
                         1,500                                                                                                     $15.0
                         1,250
                                                                                                   $8.9       $7.3
                         1,000                                                             $7.5                                    $10.0
                          750                                                      $5.4
                                                                  $3.6    $3.9
                          500                   $1.5     $2.2                                                                      $5.0
                                         $1.3
                          250     $0.7
                                         287     398     641      832     1,101   1,253    1,361   1,466     1,436      1,449
                            0    175                                                                                               $0.0
                                 2010    2011   2012     2013    2014     2015    2016     2017    2018      2019       2020
                                                                                                      Source: PitchBook and Capstone Research

   NOTABLE VENTURE CAPITAL TRANSACTIONS
                                         GoForward, Inc., operator of concierge primary care clinics, secured $225 million in series
                                         D funding in March, led by SoftBank Group. GoForward offers a subscription-based
                                         package through its mobile app to provide patients with real-time blood testing and
                                         home monitoring of vitals. The funding will be utilized to enhance its Forward at Home
                                         program, sending patients specialized sensors for remote care and progress tracking.

                                         San Francisco-based Hinge Health, Inc., provider of digital healthcare kits to treat chronic
                                         musculoskeletal conditions (MSK), raised $300 million in series D funding led by Tiger
                                         Global Management in January. With a 300% revenue increase in 2020 and a post-
                                         money valuation of $3 billion, investors expect revenue to triple in 2021, according to a
                                         press release.13

                                         China’s leading healthcare community platform, DXY, secured $500 million in series E
                                         funding in December, led by TrustBridge Partners. DXY’s platform connects Chinese
                                         consumers with healthcare organizations such as Pfizer (NYSE:PFE) for medical
                                         consultations. The funds will be utilized to strengthen cooperation with hospitals and
                                         pharmaceutical companies as it continues to provide real-time COVID-19 tracking.14

                                         ScriptDrop, Inc., a startup developer of a prescription delivery platform, secured $15
                                         million in series A funding in October, generating a $130 million post-money valuation.
                                         “They [ScriptDrop] were bringing their health care expertise to a new company, including
                                         technology and cybersecurity knowledge, along with partnerships with major pharmacy
                                         chains,” commented lead investor and Ohio Innovation Fund Managing Director Bill
                                         Baumel, according to a press release.15

                                                                                                                                                                      13
Healthcare IT | May 2021

PUBLIC COMPANY DATA

                                           Price    % 52 Wk     Market      Enterprise                   LTM                          EV / LTM
Company                                 05/17/21       High        Cap             Value     Revenue       EBITDA      Margin    Revenue    EBITDA
Accolade, Inc.                            $42.51      65.1%    $2,494.1       $2,060.2         $170.4            NM       NA      12.1x        NM

Allscripts Healthcare Solutions, Inc.     $16.94      94.3%    $2,391.3        $2,157.7       $1,489.7         $76.6     5.1%      1.4x       28.2x

Ascom Holding AG                         $15.40       88.1%     $554.4            $540.2       $317.6          $16.7     5.3%      1.7x        NM

Benefitfocus, Inc.                        $14.22      80.9%      $471.8           $634.2       $267.1          $32.2    12.0%     2.4x        19.7x

Castlight Health, Inc.                     $1.80      76.3%     $284.3            $240.5       $142.7           $1.7     1.2%      1.7x        NM

Cerner Corporation                       $76.80       91.2%    $23,141.2     $23,534.0       $5,481.8      $1,299.7     23.7%     4.3x        18.1x

Change Healthcare Inc.                   $22.88       94.5%    $6,973.5       $11,797.8       $2,432.1         $0.0     0.0%      4.9x         NM

Evolent Health, Inc.                      $19.98      89.4%    $1,706.2        $1,766.7       $1,016.3          $7.6     0.7%      1.7x        NM

HealthStream, Inc.                       $25.87       97.6%      $816.0           $787.7       $246.7          $36.2    14.7%     3.2x        21.8x

GoHealth, Inc.                            $11.44      43.6%     $1,143.9      $2,322.0        $940.5           $44.5     4.7%     2.5x         NM

Inovalon Holdings, Inc.                   $30.71      98.2%    $4,786.7       $5,675.9        $690.5       $204.4      29.6%      8.2x        27.8x

Omnicell, Inc.                            $131.91     89.7%    $5,697.2        $5,679.1        $914.4          $99.4    10.9%     6.2x         NM

One Medical (1LifeHealthcare)            $32.76       54.8%    $4,497.6       $4,287.3         $422.8            NM       NA      10.1x        NM

Premier, Inc.                            $34.34       90.9%    $4,198.7       $4,749.5        $1,582.4     $406.3       25.7%     3.0x        11.7x

Vocera Communications, Inc.              $33.34      60.0%      $1,145.8       $1,070.7       $206.4            $7.8     3.8%     5.2x         NM

IQVIA Holdings Inc.                     $234.04       98.6%   $44,856.4      $55,365.4       $12,014.0     $1,981.0     16.5%     4.6x        27.9x

EV = enterprise value; LTM = last twelve months                            Mean                                         11.0%     4.6x        22.2x
$ in millions, except per share data
NM = Not Meaningful, above 30x EBITDA                                      Median                                        8.1%     3.7x        21.8x

                                                                           Harmonic Mean                                  NA       3.1x      20.3x

PUBLIC COMPANY DATA: TELEHEALTH

                                           Price    % 52 Wk     Market      Enterprise                   LTM                          EV / LTM
Company                                 05/17/21       High        Cap             Value     Revenue       EBITDA      Margin    Revenue    EBITDA
American Well Corporation                  $11.71     26.8%    $2,822.5        $1,853.5        $249.2            NM       NA      7.4x         NM

Hims & Hers Health, Inc.                  $8.84       34.8%    $1,695.4           $1,845.1      $171.0           NM       NA      10.8x        NM

LifeMD, Inc.                              $8.78       26.6%     $228.9             $219.4        $51.2           NM       NA      4.3x         NM

Ontrak, Inc.                              $32.18      32.2%     $570.8            $527.8        $99.2            NM       NA      5.3x         NM

Teladoc Health, Inc.                    $139.68       45.4%   $21,584.2      $22,290.6       $1,366.8            NM       NA      16.3x        NM

                                                                           Mean                                           NA      8.8x         NA

                                                                           Median                                         NA      7.4x         NA

                                                                           Harmonic Mean                                  NA      7.0x         NA

                                                                                                                   Source: Capital IQ as of May 17, 2021

                                                                                                                                                           14
Healthcare IT | May 2021

HEALTHCARE IT REPORT CONTRIBUTORS

           David DeSimone
           Managing Director
           ddesimone@capstonepartners.com | 617-619-3324

           David is a Managing Director in the Technology Media & Telecom Group. David brings
           more than 20 years of investment banking experience to Capstone Partners and will
           help expand the firm’s technology sector coverage. David has worked on equity, debt
           and M&A transactions collectively valued at more than $4 billion. Previously, David was a
           member of the Capstone team for nearly seven years where he led efforts in the
           Technology Solutions vertical as a Vice President and Director. Prior to rejoining
           Capstone, David served as a Principal at Bowen Advisors, an M&A and strategic advisory
           firm focused on technology companies including communications and healthcare IT.

           David has also worked as a Vice President at Boenning & Scattergood, a Philadelphia-
           based middle market investment bank, where he worked with clients across a variety of
           industries and developed the firm’s technology practice. He spent his early career
           working at Needham & Company, RobertsonStephens and J.P. Morgan.

           David Michaels
           Managing Director, Head of Technology, Media, & Telecom Practice
           dmichaels@capstonepartners.com | 858-926-5950

           David is a Managing Director of Capstone where he is responsible for managing the
           firm’s Technology, Media & Telecom Group. David founded SagePoint Advisors in 2008,
           a boutique investment banking firm focused on providing M&A advisory services to
           technology and telecom companies. Prior to founding SagePoint, David was a Co-
           Founder, Partner and Managing Director at Montgomery & Co., a leading investment
           bank focused on serving emerging-growth technology companies. David co-founded
           Montgomery’s investment banking business in 1996 and played an instrumental role in
           building the business to over $50 million in revenues and 80 employees. He also ran the
           firm’s Communications and Digital Media Technology practice areas prior to his
           departure.

           David has intimate knowledge of the strategic landscape, market dynamics and
           technology underpinnings of several high technology market segments including Mobile
           Software & Services, Consumer Internet, E-Commerce, Enterprise SaaS, Cloud &
           Infrastructure Software and Consumer, IT & Telecom Hardware. Prior to joining
           Montgomery in 1994, David worked as an investment banker at Bankers Trust and prior
           to that, as a structural engineer at General Dynamics.

           Max Morrissey
           Research Associate
           mmorrissey@capstonepartners.com | 617-619-3336

           Max is a Research Associate at Capstone Partners with a primary focus on the
           Technology, Media, & Telecom, Business Services, and Education & Training industries.
           Before joining the corporate Research Team at Capstone Partners, Max was an analyst at
           Lab42 Research, a Chicago-based market research firm. At Lab42 Research he
           specialized in the development and analysis of propriety research projects with a focus
           in quantitative methodology. Max has a BS in Economics and a BS in Marketing from
           DePaul University.

                                                                                                       15
Healthcare IT | May 2021

FIRM TRACK RECORD

                   CONFIDENTIAL                             CONFIDENTIAL                          CONFIDENTIAL

                        CORPORATE SALE                       CORPORATE SALE                            CORPORATE SALE
                          (IN MARKET)                          (IN MARKET)                               (IN MARKET)

                        ARTIFICIAL
                                                                 ARTIFICIAL                               SENSOR
                     INTELLIGENCE &
                                                             INTELLIGENCE & EHR                         TECHNOLOGY
                    MACHINE LEARNING

                                           SERVICES GROUP

                                         HAS RECEIVED DEBT                                                                 HAS BEEN
 HAS BEEN ACQUIRED BY                                                       HAS BEEN ACQUIRED BY
                                          FINANCING FROM                                                                RECAPITALIZED BY

 HAS BEEN ACQUIRED BY               HAS BEEN ACQUIRED BY                     HAS PARTNERED WITH                      HAS BEEN ACQUIRED BY

HAS RAISED $30 MILLION
                                    HAS BEEN ACQUIRED BY                    HAS BEEN ACQUIRED BY                     HAS BEEN ACQUIRED BY
OF EQUITY CAPITAL FROM

                                                                              a portfolio company of
                                                                            AUDAX GROUP, INC.

 HAS BEEN ACQUIRED BY               HAS BEEN ACQUIRED BY                    HAS BEEN ACQUIRED BY                     HAS BEEN ACQUIRED BY

                                                                                                                                            16
Healthcare IT | May 2021

ENDNOTES

1.       McKinsey & Company, “Five Stages for Healthcare Institutions in Battle Against COVID-19,”
         https://www.mckinsey.com/industries/healthcare-systems-and-services/our-insights/from-wartime-to-peacetime-five-stages-
         for-healthcare-institutions-in-the-battle-against-covid-19, accessed March 24, 2021.
2.       Accenture, “How Can Leaders Make Recent Digital Health Gains Last,” https://www.accenture.com/us-en/insights/health/leaders-
         make-recent-digital-health-gains-last, accessed March 24, 2021.
3.       Teledoc Health, “Teledoc Health Reports Fourth-Quarter and Full-Year 2020 Results,”
         https://s21.q4cdn.com/672268105/files/doc_financials/2020/q4/TDOC-EPR-4Q20.pdf, accessed March 24, 2021.
4.       Markets and Markets, “Healthcare Cloud Computing Market Global Forecasts to 2025,”
         https://www.marketsandmarkets.com/Market-Reports/cloud-computing-healthcare-market-347.html, accessed March 23, 2021.
5.       L&T Technology Services, “Digital Front Door Survey Whitepaper,” https://bizclik-cms-prod.s3.eu-west-
         2.amazonaws.com/mailchimp/downloads/DFD+WhitepaperV9_compressed.pdf, accessed March 23, 2021.
6.       Center for Connected Medicine, “Research Report: COVID-19 Pandemic Shifts Innovation Priorities at Health Systems,”
         https://connectedmed.com/resources/research-report-covid-19-pandemic-shifts-innovation-priorities-at-health-systems/,
         accessed March 23, 2021.
7.       HIT Infrastructure, “Microsoft Azure Forms Collaboration to Enhance AI in Healthcare,”
         https://hitinfrastructure.com/news/microsoft-azure-forms-collaboration-to-enhance-ai-in-healthcare, accessed March 22, 2021.
8.       Amazon, “Amazon Care to Launch across U.S. this Summer,” https://www.aboutamazon.com/news/workplace/amazon-care-to-
         launch-across-u-s-this-summer-offering-millions-of-individuals-and-families-immediate-access-to-high-quality-medical-
         care-and-advice-24-hours-a-day-365-days-a-year, accessed March 22, 2021.
9.       MedCityNews, “CVS Caremark Adds Five Companies to Digital Health Platform,” https://medcitynews.com/2020/03/caremark-
         adds-five-companies-to-digital-health-platform/?rf=1, accessed March 22, 2021.
10.      Walmart, “Walmart Empowering Individuals with Access to Digital Health Records,”
         https://corporate.walmart.com/newsroom/2021/03/17/walmart-empowering-individuals-with-access-to-digital-health-records-
         in-partnership-with-the-commons-project-foundation-and-clear, accessed March 22, 2021.
11.      Healthcare IT News, “Optum to Acquire Change Healthcare in $13B Deal,” https://www.healthcareitnews.com/news/optum-
         acquire-change-healthcare-13b-deal, accessed March 21, 2021.
12.      WELL Health, “WELL Health Achieves Record Revenue and Positive Adjusted EBITDA in Q4-2020,”
         https://www.well.company/_resources/News/nr_20210318.pdf, accessed March 21, 2021.
13.      Tech Crunch, “Hinge Health has Raised $300M Series D at a $3B Valuation,” https://techcrunch.com/2021/01/05/hinge-healthy-
         d/, accessed March 21, 2021.
14.      Tech Crunch, “Tencent Backs Chinese Healthcare Portal DXY in $500M Round,” https://techcrunch.com/2020/12/28/china-dxy-
         500-million-funding-tencent/, accessed March 21, 2021.
15.      Crunchbase, “ScriptDrop Raises $15M Series A For Pharmacy Delivery Platform,” https://news.crunchbase.com/news/scriptdrop-
         raises-15m-series-a-for-pharmacy-delivery-platform/, accessed March 21, 2021.

                                          Common Goals. Uncommon Results.

      Disclosure
      This report is a periodic compilation of certain economic and corporate information, as well as completed and announced merger and
      acquisition activity. Information contained in this report should not be construed as a recommendation to sell or buy any security. Any
      reference to or omission of any reference to any company in this report should not be construed as a recommendation to buy, sell or
      take any other action with respect to any security of any such company. We are not soliciting any action with respect to any security
      or company based on this report. The report is published solely for the general information of clients and friends of Capstone
      Partners. It does not take into account the particular investment objectives, financial situation or needs of individual recipients.
      Certain transactions, including those involving early-stage companies, give rise to substantial risk and are not suitable for all investors.
      This report is based upon information that we consider reliable, but we do not represent that it is accurate or complete, and it should not
      be relied upon as such. Prediction of future events is inherently subject to both known and unknown risks and other factors that may
      cause actual results to vary materially. We are under no obligation to update the information contained in this report. Opinions
      expressed are our present opinions only and are subject to change without notice. Additional information is available upon request.
      The companies mentioned in this report may be clients of Capstone Partners. The decisions to include any company in this report is
      unrelated in all respects to any service that Capstone Partners may provide to such company. This report may not be copied or
      reproduced in any form or redistributed without the prior written consent of Capstone Partners. The information contained herein should
      not be construed as legal advice.

                                                                                                                                                     17
Market Presence
With a long-established U.S. footprint, together with an international partner
platform, we provide clients with broad expertise and access to key market
relationships on a global basis. Our presence is backed by ~200 professionals in the
U.S. with 450+ professionals across 43 countries.

          218                      $12.5B                                           30%                                  6th
   M&A transactions                   aggregate                                     of our deals                   globally ranked for
  completed in 2020               transaction value                                  are cross-                    deals under $500m
                                                                                       border

               $65.1M                                           51                                       65%
                     average                       deals involving foreign                          completed with a
                   transaction                      private equity firms                            European partner
                      value

     United States                                                        International

 170+ professionals               450+ professionals
 12 offices                       60+ offices in 43 countries

 Boston · Chicago · Dallas ·      Asia: China · India · Japan · Thailand
 Denver Detroit · Los Angeles ·   Africa: Congo · Egypt · Ghana · Ivory Coast · Mauritius · Morocco · Nigeria · Senegal · South Africa
 New York Orange County ·         Americas: Toronto · Vancouver · Argentina · Brazil · Chile · Colombia · Mexico · Panama & Central
 Philadelphia Richmond · San      America · Peru
 Diego · Tampa                    Europe: Belgium · Bosnia & Herzegovina · Croatia · Czech Republic · Finland · France · Germany ·
                                  Hungary · Ireland
                                  Italy · Netherlands · Poland · Portugal · Russia · Serbia · Slovakia · Slovenia · Spain · Sweden ·
                                  United Kingdom

                                               capstonepartners.com
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