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Items 1-47 of 47 (Display the 47 citations in PubMed)

1. Multimodality multiparametric imaging of early tumor response to a novel
   antiangiogenic therapy based on anticalins.
   Meier R, Braren R, Kosanke Y, Bussemer J, Neff F, Wildgruber M,
   Schwarzenböck S, Frank A, Haller B, Hohlbaum AM, Schwaiger M, Gille H,
   Rummeny EJ, Beer AJ.
   PLoS One. 2014 May 6;9(5):e94972. doi: 10.1371/journal.pone.0094972.
   eCollection 2014.
   PMID: 24801709 Free PMC article.
2. Prediction of Tumor Cellularity in Resectable PDAC from Preoperative
   Computed Tomography Imaging.
   Jungmann F, Kaissis GA, Ziegelmayer S, Harder F, Schilling C, Yen HY,
   Steiger K, Weichert W, Schirren R, Demir IE, Friess H, Makowski MR,
   Braren RF, Lohöfer FK.
   Cancers (Basel). 2021 Apr 25;13(9):2069. doi: 10.3390/cancers13092069.
   PMID: 33922981 Free PMC article.
3. Hyperpolarized 13C Spectroscopy with Simple Slice-and-Frequency-Selective
   Excitation.
   Topping GJ, Heid I, Trajkovic-Arsic M, Kritzner L, Grashei M,
   Hundshammer C, Aigner M, Skinner JG, Braren R, Schilling F.
   Biomedicines. 2021 Jan 27;9(2):121. doi: 10.3390/biomedicines9020121.
   PMID: 33513763 Free PMC article.
4. Hyperpolarized 13C pyruvate magnetic resonance spectroscopy for in vivo
   metabolic phenotyping of rat HCC.
   Bliemsrieder E, Kaissis G, Grashei M, Topping G, Altomonte J,
   Hundshammer C, Lohöfer F, Heid I, Keim D, Gebrekidan S, Trajkovic-Arsic
   M, Winkelkotte A, Steiger K, Nawroth R, Siveke J, Schwaiger M, Makowski
   M, Schilling F, Braren R.
   Sci Rep. 2021 Jan 13;11(1):1191. doi: 10.1038/s41598-020-80952-4.
   PMID: 33441943 Free PMC article.
5. Qualitative and Quantitative Comparison of Respiratory Triggered Reduced
   Field-of-View (FOV) Versus Full FOV Diffusion Weighted Imaging (DWI)
   in Pancreatic Pathologies.
   Harder FN, Kamal O, Kaissis GA, Heid I, Lohöfer FK, McTavish S, Van AT,
   Katemann C, Peeters JM, Karampinos DC, Makowski MR, Braren RF.
   Acad Radiol. 2020 Dec 31:S1076-6332(20)30704-2. doi:
   10.1016/j.acra.2020.12.011. Online ahead of print.
   PMID: 33390324
6. Deep Convolutional Neural Network-Assisted Feature Extraction for
   Diagnostic Discrimination and Feature Visualization in Pancreatic Ductal
   Adenocarcinoma (PDAC) versus Autoimmune Pancreatitis (AIP).
Ziegelmayer S, Kaissis G, Harder F, Jungmann F, Müller T, Makowski M,
      Braren R.
      J Clin Med. 2020 Dec 11;9(12):4013. doi: 10.3390/jcm9124013.
      PMID: 33322559 Free PMC article.
7.    [Artificial intelligence and machine learning in oncologic imaging].
      Kleesiek J, Murray JM, Strack C, Prinz S, Kaissis G, Braren R.
      Pathologe. 2020 Nov;41(6):649-658. doi: 10.1007/s00292-020-00827-3.
      PMID: 33052431 German.
8.    Implementing cell-free DNA of pancreatic cancer patient-derived organoids
      for personalized oncology.
      Dantes Z, Yen HY, Pfarr N, Winter C, Steiger K, Muckenhuber A, Hennig A,
      Lange S, Engleitner T, Öllinger R, Maresch R, Orben F, Heid I, Kaissis G,
      Shi K, Topping G, Stögbauer F, Wirth M, Peschke K, Papargyriou A, Rezaee-
      Oghazi M, Feldmann K, Schäfer AP, Ranjan R, Lubeseder-Martellato C,
      Stange DE, Welsch T, Martignoni M, Ceyhan GO, Friess H, Herner A, Liotta
      L, Treiber M, von Figura G, Abdelhafez M, Klare P, Schlag C, Algül H,
      Siveke J, Braren R, Weirich G, Weichert W, Saur D, Rad R, Schmid RM,
      Schneider G, Reichert M.
      JCI Insight. 2020 Aug 6;5(15):e137809. doi: 10.1172/jci.insight.137809.
      PMID: 32614802 Free PMC article.
9.    Prognostic factors in hepatocellular carcinoma patients undergoing
      transarterial chemoembolization and radioembolization: a retrospective study.
      Jeliazkova P, Umgelter A, Braren R, Kaissis G, Mustafa M, Einwächter H.
      Eur J Gastroenterol Hepatol. 2020 Aug;32(8):1036-1041. doi:
      10.1097/MEG.0000000000001625.
      PMID: 31851090
10.   Multiparametric Modelling of Survival in Pancreatic Ductal Adenocarcinoma
      Using Clinical, Histomorphological, Genetic and Image-Derived Parameters.
      Kaissis GA, Jungmann F, Ziegelmayer S, Lohöfer FK, Harder FN, Schlitter
      AM, Muckenhuber A, Steiger K, Schirren R, Friess H, Schmid R, Weichert
      W, Makowski MR, Braren RF.
      J Clin Med. 2020 Apr 25;9(5):1250. doi: 10.3390/jcm9051250.
      PMID: 32344944 Free PMC article.
11.   Image-Based Molecular Phenotyping of Pancreatic Ductal Adenocarcinoma.
      Kaissis GA, Ziegelmayer S, Lohöfer FK, Harder FN, Jungmann F, Sasse D,
      Muckenhuber A, Yen HY, Steiger K, Siveke J, Friess H, Schmid R, Weichert
      W, Makowski MR, Braren RF.
      J Clin Med. 2020 Mar 7;9(3):724. doi: 10.3390/jcm9030724.
      PMID: 32155990 Free PMC article.
12.   Combined DCE-MRI- and FDG-PET enable histopathological grading
      prediction in a rat model of hepatocellular carcinoma.
      Kaissis GA, Lohöfer FK, Hörl M, Heid I, Steiger K, Munoz-Alvarez KA,
      Schwaiger M, Rummeny EJ, Weichert W, Paprottka P, Braren R.
      Eur J Radiol. 2020 Mar;124:108848. doi: 10.1016/j.ejrad.2020.108848. Epub
      2020 Jan 23.
PMID: 32006931
13.   [A primer on machine learning].
      Kleesiek J, Murray JM, Strack C, Kaissis G, Braren R.
      Radiologe. 2020 Jan;60(1):24-31. doi: 10.1007/s00117-019-00616-x.
      PMID: 31811324 Review. German.
14.   [A primer on radiomics].
      Murray JM, Kaissis G, Braren R, Kleesiek J.
      Radiologe. 2020 Jan;60(1):32-41. doi: 10.1007/s00117-019-00617-w.
      PMID: 31820014 Review. German.
15.   Acceleration of chemical shift encoding-based water fat MRI for liver proton
      density fat fraction and T2* mapping using compressed sensing.
      Lohöfer FK, Kaissis GA, Müller-Leisse C, Franz D, Katemann C, Hock A,
      Peeters JM, Rummeny EJ, Karampinos D, Braren RF.
      PLoS One. 2019 Nov 15;14(11):e0224988. doi:
      10.1371/journal.pone.0224988. eCollection 2019.
      PMID: 31730658 Free PMC article.
16.   A machine learning model for the prediction of survival and tumor subtype in
      pancreatic ductal adenocarcinoma from preoperative diffusion-weighted
      imaging.
      Kaissis G, Ziegelmayer S, Lohöfer F, Algül H, Eiber M, Weichert W, Schmid
      R, Friess H, Rummeny E, Ankerst D, Siveke J, Braren R.
      Eur Radiol Exp. 2019 Oct 17;3(1):41. doi: 10.1186/s41747-019-0119-0.
      PMID: 31624935 Free PMC article.
17.   A machine learning algorithm predicts molecular subtypes in pancreatic
      ductal adenocarcinoma with differential response to gemcitabine-based versus
      FOLFIRINOX chemotherapy.
      Kaissis G, Ziegelmayer S, Lohöfer F, Steiger K, Algül H, Muckenhuber A,
      Yen HY, Rummeny E, Friess H, Schmid R, Weichert W, Siveke JT, Braren R.
      PLoS One. 2019 Oct 2;14(10):e0218642. doi: 10.1371/journal.pone.0218642.
      eCollection 2019.
      PMID: 31577805 Free PMC article.
18.   Camera-based respiratory triggering improves the image quality of 3D
      magnetic resonance cholangiopancreatography.
      Harder F, Lohöfer FK, Kaissis GA, Zoellner C, Kamal O, Katemann C, Hock
      A, Senegas J, Peeters JM, Rummeny EJ, Karampinos D, Braren RF.
      Eur J Radiol. 2019 Nov;120:108675. doi: 10.1016/j.ejrad.2019.108675. Epub
      2019 Sep 23.
      PMID: 31585303
19.   Differential Diagnosis for Pancreatic Cysts in CT Scans Using Densely-
      Connected Convolutional Networks.
      Li H, Shi K, Reichert M, Lin K, Tselousov N, Braren R, Fu D, Schmid R, Li
      J, Menze B.
      Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul;2019:2095-2098. doi:
      10.1109/EMBC.2019.8856745.
      PMID: 31946314
20. Pancreatic cancer detection and characterization-state of the art cross-
    sectional imaging and imaging data analysis.
    Kaissis G, Braren R.
    Transl Gastroenterol Hepatol. 2019 May 21;4:35. doi:
    10.21037/tgh.2019.05.04. eCollection 2019.
    PMID: 31231702 Free PMC article. Review.
21. Magnetic resonance cholangiopancreatography at 3 Tesla: Image quality
    comparison between 3D compressed sensing and 2D single-shot acquisitions.
    Lohöfer FK, Kaissis GA, Rasper M, Katemann C, Hock A, Peeters JM,
    Schlag C, Rummeny EJ, Karampinos D, Braren RF.
    Eur J Radiol. 2019 Jun;115:53-58. doi: 10.1016/j.ejrad.2019.04.002. Epub
    2019 Apr 15.
    PMID: 31084759
22. Borderline-resectable pancreatic adenocarcinoma: Contour irregularity of the
    venous confluence in pre-operative computed tomography predicts
    histopathological infiltration.
    Kaissis GA, Lohöfer FK, Ziegelmayer S, Danner J, Jäger C, Schirren R,
    Ankerst D, Ceyhan GO, Friess H, Rummeny EJ, Weichert W, Braren RF.
    PLoS One. 2019 Jan 2;14(1):e0208717. doi: 10.1371/journal.pone.0208717.
    eCollection 2019.
    PMID: 30601813 Free PMC article.
23. Improved detection rates and treatment planning of head and neck cancer
    using dual-layer spectral CT.
    Lohöfer FK, Kaissis GA, Köster FL, Ziegelmayer S, Einspieler I, Gerngross
    C, Rasper M, Noel PB, Koerdt S, Fichter A, Rummeny EJ, Braren RF.
    Eur Radiol. 2018 Dec;28(12):4925-4931. doi: 10.1007/s00330-018-5511-2.
    Epub 2018 May 28.
    PMID: 29808428
24. Apparent Diffusion Coefficient (ADC) predicts therapy response in pancreatic
    ductal adenocarcinoma.
    Trajkovic-Arsic M, Heid I, Steiger K, Gupta A, Fingerle A, Wörner C,
    Teichmann N, Sengkwawoh-Lueong S, Wenzel P, Beer AJ, Esposito I, Braren
    R, Siveke JT.
    Sci Rep. 2017 Dec 6;7(1):17038. doi: 10.1038/s41598-017-16826-z.
    PMID: 29213099 Free PMC article.
25. Imaging and targeted therapy of pancreatic ductal adenocarcinoma using the
    theranostic sodium iodide symporter (NIS) gene.
    Schmohl KA, Gupta A, Grünwald GK, Trajkovic-Arsic M, Klutz K, Braren
    R, Schwaiger M, Nelson PJ, Ogris M, Wagner E, Siveke JT, Spitzweg C.
    Oncotarget. 2017 May 16;8(20):33393-33404. doi:
    10.18632/oncotarget.16499.
    PMID: 28380420 Free PMC article.
26. Integrin-Targeted Hybrid Fluorescence Molecular Tomography/X-ray
    Computed Tomography for Imaging Tumor Progression and Early Response
    in Non-Small Cell Lung Cancer.
Ma X, Phi Van V, Kimm MA, Prakash J, Kessler H, Kosanke K, Feuchtinger
      A, Aichler M, Gupta A, Rummeny EJ, Eisenblätter M, Siveke J, Walch AK,
      Braren R, Ntziachristos V, Wildgruber M.
      Neoplasia. 2017 Jan;19(1):8-16. doi: 10.1016/j.neo.2016.11.009. Epub 2016
      Dec 7.
      PMID: 27940248 Free PMC article.
27.   Targeting PI3K/mTOR signaling exerts potent antitumor activity in
      pheochromocytoma in vivo.
      Lee M, Minaskan N, Wiedemann T, Irmler M, Beckers J, Yousefi BH, Kaissis
      G, Braren R, Laitinen I, Pellegata NS.
      Endocr Relat Cancer. 2017 Jan;24(1):1-15. doi: 10.1530/ERC-16-0324. Epub
      2016 Nov 3.
      PMID: 27811202
28.   Co-clinical Assessment of Tumor Cellularity in Pancreatic Cancer.
      Heid I, Steiger K, Trajkovic-Arsic M, Settles M, Eßwein MR, Erkan M,
      Kleeff J, Jäger C, Friess H, Haller B, Steingötter A, Schmid RM, Schwaiger
      M, Rummeny EJ, Esposito I, Siveke JT, Braren RF.
      Clin Cancer Res. 2017 Mar 15;23(6):1461-1470. doi: 10.1158/1078-
      0432.CCR-15-2432. Epub 2016 Sep 23.
      PMID: 27663591
29.   Tumor Uptake of Anti-CD20 Fabs Depends on Tumor Perfusion.
      Mendler CT, Feuchtinger A, Heid I, Aichler M, D'Alessandria C, Pirsig S,
      Blechert B, Wester HJ, Braren R, Walch A, Skerra A, Schwaiger M.
      J Nucl Med. 2016 Dec;57(12):1971-1977. doi: 10.2967/jnumed.116.176784.
      Epub 2016 Jul 14.
      PMID: 27417649
30.   Multiparametric human hepatocellular carcinoma characterization and therapy
      response evaluation by hyperpolarized (13) C MRSI.
      Düwel S, Durst M, Gringeri CV, Kosanke Y, Gross C, Janich MA, Haase A,
      Glaser SJ, Schwaiger M, Schulte RF, Braren R, Menzel MI.
      NMR Biomed. 2016 Jul;29(7):952-60. doi: 10.1002/nbm.3561. Epub 2016
      May 16.
      PMID: 27195474
31.   Transarterial Administration of Oncolytic Viruses for Locoregional Therapy
      of Orthotopic HCC in Rats.
      Altomonte J, Muñoz-Álvarez KA, Shinozaki K, Baumgartner C, Kaissis G,
      Braren R, Ebert O.
      J Vis Exp. 2016 Apr 15;(110):53757. doi: 10.3791/53757.
      PMID: 27167921 Free PMC article.
32.   Multiplexed pancreatic genome engineering and cancer induction by
      transfection-based CRISPR/Cas9 delivery in mice.
      Maresch R, Mueller S, Veltkamp C, Öllinger R, Friedrich M, Heid I, Steiger
      K, Weber J, Engleitner T, Barenboim M, Klein S, Louzada S, Banerjee R,
      Strong A, Stauber T, Gross N, Geumann U, Lange S, Ringelhan M, Varela I,
Unger K, Yang F, Schmid RM, Vassiliou GS, Braren R, Schneider G,
      Heikenwalder M, Bradley A, Saur D, Rad R.
      Nat Commun. 2016 Feb 26;7:10770. doi: 10.1038/ncomms10770.
      PMID: 26916719 Free PMC article.
33.   Modeling Therapy Response and Spatial Tissue Distribution of Erlotinib in
      Pancreatic Cancer.
      Grüner BM, Winkelmann I, Feuchtinger A, Sun N, Balluff B, Teichmann N,
      Herner A, Kalideris E, Steiger K, Braren R, Aichler M, Esposito I, Schmid
      RM, Walch A, Siveke JT.
      Mol Cancer Ther. 2016 May;15(5):1145-52. doi: 10.1158/1535-7163.MCT-
      15-0165. Epub 2016 Jan 28.
      PMID: 26823494
34.   [Multifocal tumors in a 56-year-old male patient].
      Kaissis G, Eiber M, Becker V, Holzapfel K, Rummeny EJ, Braren R.
      Radiologe. 2015 Nov;55(11):1009-13. doi: 10.1007/s00117-015-0037-y.
      PMID: 26515284 German. No abstract available.
35.   CRISPR/Cas9 somatic multiplex-mutagenesis for high-throughput functional
      cancer genomics in mice.
      Weber J, Öllinger R, Friedrich M, Ehmer U, Barenboim M, Steiger K, Heid I,
      Mueller S, Maresch R, Engleitner T, Gross N, Geumann U, Fu B, Segler A,
      Yuan D, Lange S, Strong A, de la Rosa J, Esposito I, Liu P, Cadiñanos J,
      Vassiliou GS, Schmid RM, Schneider G, Unger K, Yang F, Braren R,
      Heikenwälder M, Varela I, Saur D, Bradley A, Rad R.
      Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):13982-7. doi:
      10.1073/pnas.1512392112. Epub 2015 Oct 27.
      PMID: 26508638 Free PMC article.
36.   Next-generation metabolic imaging in pancreatic cancer.
      Braren RF, Siveke JT.
      Gut. 2016 Mar;65(3):367-9. doi: 10.1136/gutjnl-2015-310518. Epub 2015 Oct
      13.
      PMID: 26464413 No abstract available.
37.   Model Matters: Differences in Orthotopic Rat Hepatocellular Carcinoma
      Physiology Determine Therapy Response to Sorafenib.
      Groß C, Steiger K, Sayyed S, Heid I, Feuchtinger A, Walch A, Heß J, Unger
      K, Zitzelsberger H, Settles M, Schlitter AM, Dworniczak J, Altomonte J,
      Ebert O, Schwaiger M, Rummeny E, Steingötter A, Esposito I, Braren R.
      Clin Cancer Res. 2015 Oct 1;21(19):4440-50. doi: 10.1158/1078-0432.CCR-
      14-2018. Epub 2015 May 20.
      PMID: 25995341
38.   Targeting PI3K/mTOR Signaling Displays Potent Antitumor Efficacy against
      Nonfunctioning Pituitary Adenomas.
      Lee M, Wiedemann T, Gross C, Leinhäuser I, Roncaroli F, Braren R,
      Pellegata NS.
      Clin Cancer Res. 2015 Jul 15;21(14):3204-15. doi: 10.1158/1078-0432.CCR-
      15-0288. Epub 2015 Apr 2.
PMID: 25838390
39.   Characterization of magnetic viral complexes for targeted delivery in
      oncology.
      Almstätter I, Mykhaylyk O, Settles M, Altomonte J, Aichler M, Walch A,
      Rummeny EJ, Ebert O, Plank C, Braren R.
      Theranostics. 2015 Mar 18;5(7):667-85. doi: 10.7150/thno.10438. eCollection
      2015.
      PMID: 25897333 Free PMC article.
40.   Multimodal molecular imaging of integrin αvβ3 for in vivo detection of
      pancreatic cancer.
      Trajkovic-Arsic M, Mohajerani P, Sarantopoulos A, Kalideris E, Steiger K,
      Esposito I, Ma X, Themelis G, Burton N, Michalski CW, Kleeff J, Stangl S,
      Beer AJ, Pohle K, Wester HJ, Schmid RM, Braren R, Ntziachristos V, Siveke
      JT.
      J Nucl Med. 2014 Mar;55(3):446-51. doi: 10.2967/jnumed.113.129619. Epub
      2014 Feb 18.
      PMID: 24549287
41.   Microvascular dysfunction in the course of metabolic syndrome induced by
      high-fat diet.
      Aoqui C, Chmielewski S, Scherer E, Eissler R, Sollinger D, Heid I, Braren R,
      Schmaderer C, Megens RT, Weber C, Heemann U, Tschöp M, Baumann M.
      Cardiovasc Diabetol. 2014 Feb 3;13:31. doi: 10.1186/1475-2840-13-31.
      PMID: 24490784 Free PMC article.
42.   Free-breathing quantitative dynamic contrast-enhanced magnetic resonance
      imaging in a rat liver tumor model using dynamic radial T(1) mapping.
      Braren R, Curcic J, Remmele S, Altomonte J, Ebert O, Rummeny EJ,
      Steingoetter A.
      Invest Radiol. 2011 Oct;46(10):624-31. doi: 10.1097/RLI.0b013e31821e30e7.
      PMID: 21577121
43.   Validation of preclinical multiparametric imaging for prediction of necrosis in
      hepatocellular carcinoma after embolization.
      Braren R, Altomonte J, Settles M, Neff F, Esposito I, Ebert O, Schwaiger M,
      Rummeny E, Steingoetter A.
      J Hepatol. 2011 Nov;55(5):1034-40. doi: 10.1016/j.jhep.2011.01.049. Epub
      2011 Feb 24.
      PMID: 21354233
44.   Assessing antiangiogenic therapy response by DCE-MRI: development of a
      physiology driven multi-compartment model using population
      pharmacometrics.
      Steingoetter A, Menne D, Braren RF.
      PLoS One. 2011;6(10):e26366. doi: 10.1371/journal.pone.0026366. Epub
      2011 Oct 18.
      PMID: 22028864 Free PMC article.
45. Reference region-based pharmacokinetic modeling in quantitative dynamic
    contract-enhanced MRI allows robust treatment monitoring in a rat liver
    tumor model despite cardiovascular changes.
    Steingoetter A, Svensson J, Kosanke Y, Botnar RM, Schwaiger M, Rummeny
    E, Braren R.
    Magn Reson Med. 2011 Jan;65(1):229-38. doi: 10.1002/mrm.22589.
    PMID: 20872863
46. Synergistic antitumor effects of transarterial viroembolization for multifocal
    hepatocellular carcinoma in rats.
    Altomonte J, Braren R, Schulz S, Marozin S, Rummeny EJ, Schmid RM,
    Ebert O.
    Hepatology. 2008 Dec;48(6):1864-73. doi: 10.1002/hep.22546.
    PMID: 19003878
47. X-ray phase-contrast CT of a pancreatic ductal adenocarcinoma mouse model.
    Tapfer A, Braren R, Bech M, Willner M, Zanette I, Weitkamp T, Trajkovic-
    Arsic M, Siveke JT, Settles M, Aichler M, Walch A, Pfeiffer F.
    PLoS One. 2013;8(3):e58439. doi: 10.1371/journal.pone.0058439. Epub 2013
    Mar 11.
    PMID: 23536795 Free PMC article.
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