São Paulo Brazil February 07-08, 2019 - International Cartilage Repair Society
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Final Programme
#ICRSWORLDSERIES
São Paulo
February 07–08, 2019
Brazil
3rd ICRS World Series
International Cartilage Regeneration
& Joint Preservation Society
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International Cartilage Regeneration & Joint Preservation Society International Cartilage Regeneration
3
70% Improvement
& Joint Preservation Society
in Osteoarthritic I N T E R N AT I O N A L C A R T I L A G E
R E G E N E R AT I O N & J O I N T P R E S E R VAT I O N
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I N T E R N AT I O N A L C A R T I L A G E
R E G E N E R AT I O N & J O I N T P R E S E R VAT I O N
SOCIETY
Knee Pain at
2 years following I NT ERN ATI O N A L CA RTI L AG E REG EN ER ATI O N
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I N T ERN AT I O N A L C A RT I L AG E R EG EN ER AT I O N
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a Single Injection3,#
International Cartilage Regeneration
INTERNATIONAL CARTI L AGE REGEN ER ATIO N
&
& J O I N T P R ES E RVAT I O N S O C I E T Y Joint Preservation Society
nSTRIDE® Autologous
Protein Solution Kit
Treating Osteoarthritic Knee Pain
Autologous Anti-Inflammatory Therapy for Knee Osteoarthritis nSTRIDE Autologous Protein Solution (APS) was developed after an extensive
The nSTRIDE APS Kit is designed to produce a novel autologous anti- research program which focused on understanding the osteoarthritic disease
inflammatory therapy to treat osteoarthritis pain in the knee via a single process in the knee and understanding the mode of action that an autologous
intra-articular injection. blood-based product could have.
The nSTRIDE APS Kit is a point of care cell-concentration system designed • Significantly Reduces Pain Associated with Knee OA up to 2 years1-3
to concentrate anti-inflammatory cytokines and anabolic growth factors to • Significantly Improves function in the Knee Joint associated with OA1-3
significantly decrease pain and promote cartilage health. nSTRIDE APS is • Effective for patients with Kellgren and Lawrence stage 2 and 3 following
suitable for treating patients who have Kellgren & Lawrence Stage 2 or 3 and a single injection 1-3,
who have failed conservative care. • 70% Improvement in Knee Pain at 2 years following a Single Injection3,#
1. Kon E, Engebretsen L , Peter Verdonk P, Nehrer S and Filardo G. “Clinical Outcomes of Knee Osteoarthritis Treated with an Autologous Protein Solution. A 1-year Pilot Double-Blinded Randomized Control Trial. American Journal of Sports Medicine, Oct. 2017.
2. Van Drumpt RA, van der Weegen W, King WJ, Toler K, Macenski M. Safety and treatment effectiveness of a single autologous protein solution injection in patients with knee osteoarthritis. BioResearch Access, Vol 5.1, 2016.
3. Kon E, Engebretsen L , Peter Verdonk P, Nehrer S and Filardo G. “Two-year Clinical Outcomes of An Autologous Protein Solution Injection For Knee Osteoarthritis.” ICRS 14th World Congress, presented, 2018.
# As measured by WOMAC pain scores reported by patients continuing follow-up through 2 years (n = 22).
This material is intended for health care professionals. Check for country product clearances and reference product specific instructions for use. For product information, including indications, contraindications, warnings, precautions, and potential adverse
effects, see the package insert and www.zimmerbiomet.com. Not for distribution in France. ©2018 Zimmer Biomet
AN FDA-APPROVED OPTION FOR PATIENTS WITH ARTICULAR CARTILAGE DEFECTS OF THE KNEE AVAILABLE ONLY IN THE U.S.
AUTOLOGOUS
CHONDROCYTE
DELIVERY, SIMPLIFIED
autologous cultured
chondrocytes
on porcine
collagen membrane
MACI builds on over 20 years success with Articular Cartilage Implantation (ACI)1
Utilizing a unique biocompatible membrane, MACI offers potential benefits over
traditional ACI through minimal incision, simplified delivery, and suture-free fixation
for the treatment of articular cartilage defects of the knee.
INDICATION IMPORTANT SAFETY INFORMATION
MACI (autologous cultured chondrocytes on porcine collagen
®
MACI is contraindicated in patients with a known history of hypersensitivity to gentamicin, other aminoglycosides, or products
membrane) is an autologous cellularized scaffold product that of porcine or bovine origin. MACI is also contraindicated for patients with severe osteoarthritis of the knee, inflammatory
is indicated for the repair of single or multiple symptomatic, arthritis, inflammatory joint disease, or uncorrected congenital blood coagulation disorders. MACI is also not indicated for
full-thickness cartilage defects of the adult knee, with or use in patients who have undergone prior knee surgery in the past 6 months, excluding surgery to procure a biopsy or a
without bone involvement. concomitant procedure to prepare the knee for a MACI implant.
MACI is intended for autologous use and must only be MACI is contraindicated in patients who are unable to follow a physician-prescribed post-surgical rehabilitation program.
administered to the patient for whom it was manufactured. The The safety of MACI in patients with malignancy in the area of cartilage biopsy or implant is unknown. Expansion of present
implantation of MACI is to be performed via an arthrotomy to malignant or dysplastic cells during the culturing process or implantation is possible.
the knee joint under sterile conditions. Patients undergoing procedures associated with MACI are not routinely tested for transmissible infectious diseases. A cartilage
The amount of MACI administered is dependent upon the biopsy and MACI implant may carry the risk of transmitting infectious diseases to healthcare providers handling the tissue.
size (surface in cm2) of the cartilage defect. The implantation Universal precautions should be employed when handling the biopsy samples and the MACI product.
membrane is trimmed by the treating surgeon to the size and Final sterility test results are not available at the time of shipping. In the case of positive sterility results, health care provider(s)
shape of the defect, to ensure the damaged area is completely will be contacted.
covered, and implanted cell-side down.
To create a favorable environment for healing, concomitant pathologies that include meniscal pathology, cruciate ligament
Limitations of Use instability and joint misalignment, must be addressed prior to or concurrent with the implantation of MACI.
Effectiveness of MACI in joints other than the knee has not Local treatment guidelines regarding the use of thromboprophylaxis and antibiotic prophylaxis around orthopaedic surgery
been established. should be followed. Use in patients with local inflammations or active infections in the bone, joint, and surrounding soft tissue
Safety and effectiveness of MACI in patients over the age of 55 should be temporarily deferred until documented recovery.
years have not been established. The MACI implant is not recommended during pregnancy. For implantations post-pregnancy, the safety of breast feeding to
infant has not been determined.
Use of MACI in pediatric patients (younger than 18 years of age) or patients over 65 years of age has not been established.
The most frequently occurring adverse reactions reported for MACI (≥5%) were arthralgia, tendonitis, back pain, joint swelling,
and joint effusion.
Serious adverse reactions reported for MACI were arthralgia, cartilage injury, meniscus injury, treatment failure, and osteoarthritis.
For more information, please see Highlights of Prescribing Information about MACI, or visit MACI.com
1. Saris D, Price A, Widuchowski W, et al. Matrix-applied characterized autologous cultured chondrocytes versus microfracture: Two-year follow-up of a prospective randomized trial. Am J Sports Med. 2014;42(6):1384-94.
MACI® is a registered trademark of Vericel Corporation. ©2018 Vericel Corporation. All rights reserved. PP.US.MAC.0261
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Caros Colegas & Amigos, I N T E R N AT I O N A L C A R T I L A G E
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A cirurgia de reparo da cartilagem articular encontra-se em desenvolvi-
mento no Brasil e na América Latina. Temos acessos a diversas técnicas,
porém é senso comum que para as lesões de cartilagem grandes, há
limitações e diferenças em relação a vários países do exterior, tornando
o tratamento de grandes defeitos um desafio para o ortopedista. Com
I NT ERN ATI O N A L CA RTI L AG E REG EN ER ATI O N I N T ERN AT I O N A L C A RT I L AG E R EG EN ER AT I O N
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grande prazer, nós lhe convidamos para o Curso de Reparo de Lesões
da Cartilagem Articular realizado sob égide da ICRS no Brasil. O curso
acontecerá em São Paulo, no Hotel Maksoud Plaza, de 07 a 09 de International Cartilage Regeneration
fevereiro de 2019. Hospedagem no hotel oficial do evento, com tarifas
INTERNATIONAL CARTI L AGE REGEN ER ATIO N
& J O I N T P R ES E RVAT I O N S O C I E T Y
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Joint Preservation Society
especiais. Pretendemos discutir e trocar experiência sobre o tratamento
de lesões grandes da cartilagem articular, com enfoque em soluções
possíveis com as tecnologias existentes para uso clínico no Brasil. Ter-
emos também aulas sobre novas tecnologias e perspectivas futuras no
tratamento de lesões condrais e osteocondrais, mas o principal objetivo
do curso é discutir soluções possíveis de serem realizadas no nosso meio.
Consideramos este aspecto a maior diferença e o maior benefício para
o ortopedista brasileiro em comparação a assistir eventos realizados no
exterior. Temos convicção que será um excelente curso!
Camila Kaleka Cohen, Moisés Cohen, Marco Demange,
Luis Eduardo Passarelli Tirico, Comissão Organizadora
Dear Friends & Colleagues,
The subspecialty of Cartilage repair is emerging in South America and es-
pecially in Brazil. We recognize that cartilage defects remain a challenge
for orthopaedic surgeons and their patients, especially for larger defects.
It is a great pleasure to invite you to the ICRS Course in Brazil, which will
be held in São Paulo from February 07 to 09, 2019 at the Maksoud Plaza
Hotel. We intend to discuss and exchange experience regarding the treat-
ment of large cartilage defects considering technology that is available
for clinical use in Brazil. Although there will be lectures discussing future
trends and novel treatments of cartilage defects, the primary aim of this
course is to present practical solutions currently available to our surgeons.
We feel this will be the most important benefit of our course comparing to
attending meetings abroad.
Camila Kaleka Cohen, Moisés Cohen, Marco Demange,
Luis Eduardo Passarelli Tirico, Local Organization Committee
Nós acreditamos em regeneração! Conheça a melhor opção para o tratamento das lesões de cartilagem! > Matriz de colágeno porcina > Experiência clínica com mais de 10 anos > Influencia na diferenciação condrogênica de células-tronco mesenquimais
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The International Cartilage Regeneration & Joint Preservation Society would like
to thank its industry partners for their generous support to the ICRS World Series.
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Diamond Partners:
International Cartilage Regeneration
INTERNATIONAL CARTI L AGE REGEN ER ATIO N
&
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Platinum Sponsors:
Silver Sponsor:
Exhibitors:
O ÚNICO VISCOSSUPLEMENTO COM
A TECNOLOGIA CROSSLINKING.1,2
• Synvisc-One® posterga a ATJ por mais
de 7 anos em
75% dos pacientes com OA Grau IV.3
• Synvisc-One®: longa duração no
alívio da dor por até 12 meses.*2,4
• Synvisc-One® é desenvolvido
especificamente Referências: 1. Instruções de uso do produto Synvisc e Synvisc One. 2. Raman R, et al. Efficacy of Hylan G-F 20
and Sodium Hyaluronate in the treatment of osteoarthritis of the knee -- A prospective randomized clinical trial. The
Knee 2008;15:318 -324. 3. Waddell DD. Delayed Total Knee Replacement with Hylan G-F 20. J Knee Surg. 2016
Feb;29(2):159-68. 4. Pal S, Thuppal S, Reddy KJ, Avasthi S, Aggarwal A, Bansal H, et al. Long-term (1-year) safety and
para imitar o líquido sinovial jovem e efficacy of a single 6-mL injection of hylan G-F 20 in indian patients with symptomatic knee osteoarthritis. The Open
Rheumatology Journal 2014;8:54-68. 5. Balazs EA, et al. Hyaluronic Acid in Synovial Fluid. I. Molecular Parameters of
Hyaluronic Acid in Normal and Arthritic Human Fluids. Arthritaisn D Rheumatismw. 1967.10(4):357-376. 6. Balazs EA1,
saudável.5-7 Denlinger JL. Viscosupplementation: a new concept in the treatment of osteoarthritis. J Rheumatol Suppl.1993;39:3-9.
7. Weiss. Musculoskeletal applications of hyaluronan and hylan. Potential uses in the foot and ankle. Clin Podiatr Med
Surg 1995;12(3): 497-517.
* OSTEOARTRITE DO JOELHO
SYNVISC-ONE (hilano G-F 20) é comercializado em uma seringa de vidro de 10 mL contendo 6 mL de hilano G-F 20. Indicações: Para administração intra-articular a ser
efetuada por um médico, para o tratamento da dor associada a osteoartrite do joelho em pacientes que falharam em responder adequadamente a terapia conservadora
não-farmacológica e analgésicos simples. Instruções para dosagem: O esquema de tratamento recomendado é de uma injeção na articulação do joelho. A injeção
pode ser repetida seis meses após a primeira injeção, se os sintomas do paciente justificarem a aplicação. Reg. MS: 80149670008.
SYNVISC OU SYNVISC-ONE. Contraindicações: Synvisc ou Synvisc-One não devem ser injetados na articulação se existir uma estase venosa ou linfática no membro
afetado. Não devem ser utilizados em articulações infectadas ou gravemente inflamadas, ou em doentes com doenças de pele ou infecções na área do local da injeção.
Advertências: Não injetar por via intravascular. Não injetar extra-articularmente ou nos tecidos ou na cápsula sinovial. Não faça uso concomitante de desinfetantes
que contenham sais quaternários de amônio para o preparo da pele, pois o hialuronato pode precipitar na presença deles. Precauções: Synvisc ou Synvisc-One não
devem ser usados se houver grande derrame intra-articular anterior à injeção. Como em qualquer procedimento invasivo em articulação, recomenda-se que o paciente
evite atividades intensas após a injeção intra-articular, e só retorne às atividades habituais depois de alguns dias. Não há estudos clínicos realizados com Synvisc e
com Synvisc-One em gestantes ou em menores de 18 anos de idade. Synvisc e Synvisc-One contêm pequenas quantidades de proteína aviária e não deve ser usado
em pacientes com hipersensibilidades relacionadas a este tipo de produto. Eventos Adversos: Eventos adversos envolvendo a articulação onde foi feita a injeção: dor
passageira e/ou inchaço e/ou derrame da articulação injetada podem ocorrer após injeções intra-articulares de Synvisc ou Synvisc-One. Em alguns casos o derrame
pode ser extenso e causar dor acentuada; é importante remover e analisar o líquido para descartar a possibilidade de infecção ou artropatias. Essas reações geralmente
diminuem no prazo de alguns dias. O benefício clínico do tratamento pode ainda ser aparente após essas reações. Última revisão: 17/01/2014
Contraindicações: Synvisc ou Synvisc-One não devem ser injetados na articulação se existir uma estase venosa ou linfática
no membro afetado. Não devem ser utilizados em articulações infectadas ou gravemente inflamadas, ou em doentes com
doenças de pele ou infecções na área do local da injeção. Nenhum outro medicamento deve ser injetado no joelho durante
o período de tratamento de Synvisc ou Synvisc One, a não ser que o médico que presta assistência ao paciente considerar o
medicamento necessário.
1
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G E R EG EN ER AT I O N
T I O N S O C I E T Y
O R G A N I S AT I O N /
&
INTERNATIONAL CARTILAGE
REGENERATION
ORGANIZAÇÃO
JOINT PRESERVATION
SOCIETY
International Cartilage Regeneration & Joint Preservation Society International Cartilage Regeneration
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International Cartilage Regeneration
I NT ERN ATI O N A L CA RTI L AG E REG EN ER ATI O N I N T ERN AT I O N A L C A RT I L AG E R EG EN ER AT I O N
& Joint Preservation Society Sociedade Internacional de Regeneração da
& J O I NT PRESERVATI O N SO CI E T Y & J O I N T PR ES ERVAT I O N S O C I E T Y
& Jointe Preservação
Cartilagem PreservationdasSociety
Articulações
International Cartilage Regeneration
INTERNATIONAL CARTI L AGE REGEN ER ATIO N
&
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Local Committee / Diretores Locais Organizing Office / Organização
Camila Kaleka Cohen (BR)
& J O I N T P R E S E R VAT I O N
SOCIETY
Moisés Cohen(BR)
Marco Demange (BR)
&
I N T E R N AT I O N A L C A R T I L A G E
R E G E N E R AT I O N
Cartilage Executive Office GmbH
J O I N T P R E S E R VAT I O N
SOCIETY
Spitalstrasse 190
Luis Eduardo Passarelli Tirico (BR) 8623 Wetzikon, Switzerland
Phone: +41 (44) 503 73 70
Email: sseiler@cartilage.org
International Faculty / Web: www.cartilage.org
Palestrantes Internacionais
Bill Bugbee, USA Course Venue / Local do Curso
Jack Farr, USA
Andreas Gomoll, USA HOTEL MAKSOUD PLAZA
Sabrina Strickland, USA Rua São Carlos do Pinhal, 424
Kenneth Zaslav, USA 01333.000 – São Paulo / SP, Brazil
G E REG EN ER ATI O NLüring, GER I N T ERN AT I O N A L C A RT I L AG E R EG EN ER AT I O N
Christian www.maksoud.com.br
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I O N SO CI E T Y
International Cartilage Regeneration
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Mark Your Agenda / Upcoming ICRS Events
GE REGEN ER ATION
ION SOCIETY Joint Preservation Society
ICRS Focus Meeting – One Step Cartilage Repair
June 05–07, 2019 – Rome, Italy
ICRS 2019 World Congress
October 05–08, 2019 – Vancouver, Canada
ICRS Focus Meeting – Imaging, Diagnosis, Treatment
November 21–23, 2019 – Vienna, Austria
FINAL PROGRAMME
Thursday, February 7, 2019
08.00–12.00 Registration
09.00–12.00 Pre-Course (Geistlich Hands-on Workshop)
Moderator: Cohen Moises (BR)
10 min O que é scaffolds? Qual é a sua função?
Lüring Christian (DE)
10 min Fluxograma do tratamento das lesões condrais
Cohen Moises (BR)
10 min Alinhamento dos membros inferiores e cartilagem. Qual é a relação?
Tirico Luis (BR)
10 min Princípios da terapia celular e aplicação prática
Cohen Kaleka Camila (BR)
10 min Procedimento em um x dois tempos cirúrgicos
Gracitelli Guilherme (BR)
10 min Lesão Focal x Artrose: o que há de evidência para uso da terapia celular
Demange Marco (BR)
10 min Preservação articular é uma realidade? Como fazemos na Alemanha?
Lüring Christian (DE)
110 min Casos Tratados
13.00–14.00 Module 1: Basic Science and Imaging in Cartilage Defects
Moderator: Cohen Moises (BR)
10 min Welcome & Introduction
Cohen Moises (BR)
10 min Clinically Relevant Aspects of Structure & Biomechanics of Articular Cartilage
Cohen Kaleka Camila (BR)
10 min Imaging on Chondral and Osteochondral Lesions
Skaf Abdalla (BR)
10 min Cartilage Markers
Antonioli Eliane (BR)
10 min Treatment Algorithms & Evidence Based Evaluation of Surgical
Cartilage Repair Techniques
Gomoll Andreas (US)
10 min Discussion& J O I N T P R E S E R VA T I O N S O C I E T Y REGENERATION & SOCIETY
FINAL PROGRAMME International Cartilage Regeneration & Joint Preservation Society International Cartilage Regeneration
& Joint Preservation Society 11
14.00–14.50 Module 2: PRP, Cytokines, & Hyaluronic
&
Acid
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Moderator: Tirico Luis (BR)
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10 min PRP & PRF – How to Prepare in the Lab and in Clinical Practice.
Conventional Centrifuges, Closed System Centrifuges and Apheresis
Almeida Adriano (BR)
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10 min Basic Science and Differences among Hyaluronic Acid
Uchoa de Rezende Marcia (BR)
10 min Clinical Evidence in the Use of PRP & Hyaluronic AcidInternational
for CartilageCartilage Regeneration
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Defects and Early OA INTERNATIONAL CARTI L AGE REGEN ER ATIO N
Joint Preservation Society
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Constantino de Campos Gustavo (BR)
10 min Genicular Nerve Block: Clinical Evidence and Clinical Results
Krause Marcelo (BR)
10 min Discussion
14.50–15.40 Module 3A: Microfracture, Autologous Osteochondral
Transplant & Mosaicplasty
Moderator: Cohen Moises (BR)
10 min Basic Science Behind Scaffolds
Demange Marco (BR)
10 min Microfracture & AMIC – Surgical Technique : Tips and Pearls
Cohen Moises (BR)
10 min Biomaterials for the Treatment of Cartilage Defects with Matrix-
augmented Bone Marrow Stimulation Technique – Technique & Literature
Lüring Christian (DE)
20 min Discussion
15.40–16.10 Coffee Break/Exhibition
16.10–17.00 Module 3B: Microfracture, Autologous Osteochondral
Transplant & Mosaicplasty
Moderator: Cohen Moises (BR)
10 min OATS, COR, Multiple Plugs Mosaicplasty Surgical Technique: Tips and Pearls
Tirico Luis (BR)
10 min Imaging on Microfracture Repair and Mosaicplasty Repair
MOCART SCORE & What to Look for?
Cavalcanti Conrado (BR)
10 min Rehabilitation, Return to Sports, Expected Short and Long-Term Results after
Microfracture & Autologous Osteochondral Transplantation
Tambascia Rafael (BR)
20 min DiscussionFINAL PROGRAMME
17.00–18.00 Module 4: Osteotomy/Osteotomia
Moderator: Demange Marco (BR)
10 min Long Limb Axis Evaluation, Patellofemoral Joint Evaluation &
Osteotomy Planning
Bugbee William (US)
10 min Valgus Tibial Osteotomy – Surgical Technique: Tips & Pearls
Gomoll Andreas (US)
10 min Varus Femoral Osteotomy- Surgical Technique: Tips & Pearls
Bugbee William (US)
10 min Patellofemoral Joint Osteotomy & Simple Trochleoplasty Surgical
Technique: Tips and Pearls
Farr Jack (US)
20 min Discussion
18.00–19.00 Module 5: Case Discussions
Moderator: Cohen Moises (BR)
50 min Clinical Cases of Simple and Complex Chondral and Osteochondral Lesions
10 min Take Home Points
Demange Marco (BR)
Friday, February 8, 2019
7.45–8.00 Highlights & Take Home Points from Day 1
8.00–9.00 Module 6: Meniscus Repair, Transplant & Substitutes
Moderator: Cohen Kaleka Camila (BR)
10 min Imaging Evaluation of Meniscal Tear and Repair
Rosemberg Laercio (BR)
10 min In-Side Out, All-Inside and Out-Side In Meniscal Suture Surgical
Technique: Tips and Pearls
Tirico Luis (BR)
10 min Meniscal Root Repair and Ramp Lesion
Cohen Moises (BR)
10 min Meniscal Transplant: Surgical Technique: Tips & Pearls
Farr Jack (US)
10 min Meniscal Substitutes, Implants and Future Trends
Cohen Kaleka Camila (BR)
10 min Discussion& J O I N T P R E S E R VA T I O N S O C I E T Y REGENERATION & SOCIETY
FINAL PROGRAMME International Cartilage Regeneration & Joint Preservation Society International Cartilage Regeneration
& Joint Preservation Society 13
9.00–9.40 Module 7: Fresh Osteochondral Transplantation
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Moderator: Tirico Luis (BR)
R E G E N E R AT I O N SOCIETY R E G E N E R AT I O N SOCIETY
10 min Historical Development & Basic Science behind Fresh
Osteochondral Transplantation
Gracitelli Guilherme (BR)
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10 min Fresh Osteochondral Allograft – Surgical Technique: Tips & Pearls
Bugbee William (US)
10 min Clinical Indications, Rehabilitation, Return to Sports, Expected Short
International Cartilage &
Regeneration
&
Long-Term Results INTERNATIONAL CARTI L AGE REGEN ER ATIO N
Joint Preservation Society
& J O I N T P R ES E RVAT I O N S O C I E T Y
Tirico Luis (BR)
10 min Discussion
9.40–10.30 Module 8: Case Discussions
Moderator: Tirico Luis (BR)
50 min Clinical Cases – Meniscus Repair, Transplant and Substitutes
What to do with and without Osteochondral Allograft available?
10.30–11.00 Coffee Break/Exhibition
11.00–12.00 Module 9: Cell Therapy – Autologous Chondrocyte Implantation (ACI)
Moderator: Cohen Moises (BR)
10 min From ACI to MACI: Cell Transplantation for Cartilage Repair
Zaslav Kenneth (US)
10 min ACI – Surgical Technique: Tips & Pearls
Zaslav Kenneth (US)
10 min ACI in the Patellofemoral Joint – Clinical Evidence
Strickland Sabrina (US)
10 min ACI Rehabilitation & Return to Sports- Expected Short & Long-Term Results
Gomoll Andreas (US)
20 min Discussion
12.00–13.00 Module 10: Case Discussions – Cell Therapy/ACI
Moderator: Demange Marco (BR)
60 min Clinical Cases – What to do With & Without Cell Therapy Available?
13.00–13.45 Lunch BreakVancouver 15Th World Congress
Canada of the International Cartilage
Regeneration &
October 5–8, 2019 Joint Preservation Society
Abstract Submission: Feb 15 – April 15, 2019
Mark your agenda!
International Cartilage Regeneration
& Joint Preservation Society www.cartilage.org& J O I N T P R E S E R VA T I O N S O C I E T Y REGENERATION & SOCIETY
FINAL PROGRAMME International Cartilage Regeneration & Joint Preservation Society International Cartilage Regeneration
& Joint Preservation Society 15
13.45–14.30 Industry Sponsored Session I N T E R N AT I O N A L C A R T I L A G E
R E G E N E R AT I O N & J O I N T P R E S E R VAT I O N
SOCIETY
I N T E R N AT I O N A L C A R T I L A G E
R E G E N E R AT I O N & J O I N T P R E S E R VAT I O N
SOCIETY
45 Minutes Sala Araguaia – Traumacamp Hands-on Workshop
The Superior Technology of a Collagen Type 1 Hydrogel
45 Minutes Sala Brasil – Sanofi Satellite Symposium – Avanços no Tratamento
Conservador da Osteoartrite do Joelho
I NT ERN ATI O N A L CA RTI L AG E REG EN ER ATI O N I N T ERN AT I O N A L C A RT I L AG E R EG EN ER AT I O N
Moderator: Tirico Luis (BR) & J O I NT PRESERVATI O N SO CI E T Y
& J O I N T PR ES ERVAT I O N S O C I E T Y
14.30–15.30 Module 11: Stem Cells & Cartilage Fragments in Cartilage Repair
Moderator: Cohen Kaleka Camila (BR) International Cartilage Regeneration
INTERNATIONAL CARTI L AGE REGEN ER ATIO N
&
Joint Preservation Society
10 min Stem Cells and Adult Mesenchymal Pluripotent Cells – Basic Science
& J O I N T P R ES E RVAT I O N S O C I E T Y
Cohen Moises (BR)
10 min Bone Marrow Derived MSC (BMAC) – Clinical Application
Demange Marco (BR)
10 min Adipose-Derived MSC – Clinical Application
Cohen Kaleka Camila (BR)
10 min Juvenile Cartilage Fragments and Minced Cartilage
Farr Jack (US)
20 min Discussion
15.30–16.00 Coffee Break/Exhibition
16.00–17.10 Module 12: Subchondral Bone and Unicompartimental Osteoarthritis
Moderator: Demange Marco (BR)
10 min Clinical Evidence on Subchondral Bone Lesions, Bone Edema &
OA Progression
Bonadio Marcelo (BR)
10 min Sub-chondral Bone Reconstruction in Cartilage Repair
Zaslav Kenneth (US)
10 min Subchondroplasty: Basic Science and Surgical Procedure
Demange Marco (BR)
10 min Tibio-Femoral Partial Arthroplasty – UKA
Bugbee William (US)
10 min Partial Ressurfacing Knee Arthroplasty & Patellofemoral Arthroplasty
Strickland Sabrina (US)
20 min Discussion
17.10–18.00 Module 13: Case Discussions / Discussão de Casos
Moderator: Demange Marco (BR)
50 min Casos Clínicos – Células Tronco, Osso Subcondral e
Osteoartrose unicompartimental
18.00–18.10 Take Home PointsPOTENCIALIZE A MOBILIDADE COM
ÁCIDO HIALURÔNICO SORBITOL
Uma formulação de Gel Inteligente que proporciona, em menos de uma semana,
RÁPIDO, INTENSO e PROLONGADO alívio da dor
em pacientes com OSTEOARTRITE.
PROPRIEDADES VISCOELÁSTICAS PATENTEADAS
QUEBRA O CICLO OXIDATIVO
MELHORA A ELASTICIDADE DA CARTILAGEM
EXCLUSIVO EFEITO VISCOANTÁLGICO
Aptíssen Brasil
DOSES ADAPTÁVEIS AO TIPO DE ARTICULAÇÃO E-mail: comercial@aptissen.com.br& J O I N T P R E S E R VA T I O N S O C I E T Y REGENERATION & SOCIETY
I N T E R N AT I O N A L FA C U L T Y International Cartilage Regeneration & Joint Preservation Society International Cartilage Regeneration
& Joint Preservation Society 17
Almeida Adriano, MD, MsC, PhD, MBA
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I N T E R N AT I O N A L C A R T I L A G E
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J O I N T P R E S E R VAT I O N I N T E R N AT I O N A L C A R T I L A G E J O I N T P R E S E R VAT I O N
Clínica Atlas Knee Surgery and Sports Medicine Sao Paulo, Brazil
R E G E N E R AT I O N SOCIETY R E G E N E R AT I O N SOCIETY
Graduated at University of São Paulo Medical School (2000), Masters and PhD at Uni-
versity of São Paulo, Brazil, Specialization: Knee Surgery, Sports Medicine at University
of São Paulo Department of Orthopedics and Traumatology, Member of the scientific
committee of SBRATE – Brazilian Society of Arthroscopy and Sports Traumatology, Ac-
tive member of: AAOS, ISAKOS, ICRS. & J OSBOT (Brazilian Society of Orthopedics and
I NT ERN ATI O N A L CA RTI L AG E REG EN ER ATI O N I N T ERN AT I O N A L C A RT I L AG E R EG EN ER AT I O N
& J O I N T PR ES ERVAT I O N S O C I E T Y
I NT PRESERVATI O N SO CI E T Y
Traumatology), SBMEE (Brazilian Society of Sports Medicine and Exercise), SBCJ (Brazil-
ian Society of Knee Surgery), Winner of the Gastao Veloso Award at Brazilian Meeting
of Orthopedics and Traumatology 2010, with the paper: “Patellar tendon regeneration
with platelet rich plasma: a prospective randomized study” International Cartilage Regeneration
INTERNATIONAL CARTI L AGE REGEN ER ATIO N
&
& J O I N T P R ES E RVAT I O N S O C I E T Y Joint Preservation Society
Antonioli Eliane, Dr., PhD
Hospital Israelita Albert Einstein Programa Locomotor São Paulo, Brazil
Eliane Antonioli is a PhD in Cellular Biology by UNICAMP (State University of Campi-
nas/SP/Brazil). Currently, Dr. Antonioli is a researcher of Orthopedic Department of
Hospital Israelita Albert Einstein, São Paulo. Her main research interests are cartilage
repair, especially in cell therapy, mesenchymal stem cells, cellular aging, and biomark-
ers for osteoarthritis. Bióloga, doutora em Biologia Celular e Estrutural pelo Instituto de
Biologia, Unicamp (2007). Realizou pós-doutoramento no Instituto Israelita de Ensino e
Pesquisa (IIEP) do Hospital Albert Einstein (2008-2011), com apoio financeiro da FAPESP.
Coordenadora do curso de Pós-Graduação Lato Sensu em Ortopedia Multiprofissional,
do Hospital Israelita Albert Einstein. Docente-colaboradora do curso de Pós-graduação Stricto-sensu Ciências
da Saúde da Sociedade Beneficente Israelita Brasileira Hospital Albert Einstein. Pesquisadora do Programa
Locomotor, do Hospital Albert Einstein. Desenvolve pesquisas com foco na regeneração da cartilagem com o
uso de terapia celular e desenvolvimento de biomateriais e envelhecimento celular.
Bonadio Marcelo, Mr., MD
São Paulo, Brazil
Marcelo Bonadio is a knee surgeon at the University of São Paulo. He is a member of
the Knee Surgery division at the University of São Paulo. He received his medical de-
gree from Medical School of the University of São Paulo in 2009. He has finished his
Residency in Orthopedics in 2012 in the Orthopedic and Traumatology Department at
the Clinics Hospital – University of São Paulo. He has done his Knee Surgery Fellowship
in the University of São Paulo in 2013 and in the University of Pennsylvania in 2016. He
is a member of the Brazilian Society of Orthopedics and Traumatology and a member
of the Brazilian Society of Knee Surgery. His main clinical and research interests are
subchondral bone and cartilage repair procedures in knee surgery.
Bugbee William, Prof., MD
Scripps Clinic Medical Group Orthopaedics La Jolla, United States of America
William Bugbee is an attending physician at Scripps Clinic, La Jolla and Professor, de-
partment of Orthopaedics, university of California, San Diego. His clinical interests are
in arthritis surgery of the hip, knee and ankle, joint replacement, osteochondral allograft
transplantation and cartilage restoration. Research interests include biologic response
to implants, innovation in knee replacement technique and design, Osteochondral trans-
plantation, cartilage tissue engineering and biologic joint repair. For CV please proceed
to www.drbugbee.comI N T E R N AT I O N A L FA C U L T Y
Cavalcanti Conrado, Dr.
Hospital Sírio-Libanês Sao Paulo, Brazil
Médico Radiologista formado pela FMUSP, com Fellow em Radiologia pela New York
University. Trabalho no Hospital Sírio-Libanês desde 2006, como gestor médico do
setor de Ressonância Magnética. Diretor acionista das empresas de diagnóstico UltraX
e Unique em São José do Rio Preto. Acionista da clínica Sua Saúde em Campinas. Dire-
tor do Colégio Brasileiro de Radiologia. Vice-presidente do Conselho Deliberativo da
Abramed.
Cohen Kaleka Camila, Dr.
Sao Paulo, Brazil
Camila Cohen Kaleka is an attending physician at Instituto Cohen and Hospital Israelita
Albert Einstein, São Paulo. Master degree at Faculdade de Ciências Médicas Santa
Casa de São Paulo. Her clinical interests are in surgery of the knee, focused in meniscus
and cartilage restoration. Research interests include mesenchymal stem cells, meniscus
preservation and substitutes, cartilage tissue engineering and biologic joint repair.
Cohen Moises, Prof., PhD
Cohen Orthopaedic Sports Medicine Institute Orthopaedic Sports
Medicine Division São Paulo, Brazil
Moises Cohen is a Full Professor and Chief of the Orthopaedic, Traumatology and
Sports Medicine Department of the Federal University of São Paulo, Brazil. He is the
Director and see the patients at the Cohen Institute of Orthopaedic, Sports Medicine
and Rehabilitation and the surgeries at the Hospital Israelita Albert Einstein, São Paulo.
His clinical interests are in degenerative and sports Knee disorders, Orthopaedic Sports
Medicine, Cartilage repair. Hes a CNPQ and FAPESP scientific investigator and he is
coordinating an important project in Genetic Study of some disorders of the Knee and
Shoulder Joints. He is a past president of the Brazilian Knee Society, Brazilian Orthopaedic Sports Medicine
Society, SLARD, ISAKOS (2011-2013). Since the beginning, he is a ICRS member as well as a member of
AAOS, ESSKA, ACL Study Group and others. Moises is the Chairman of the Medical Committee of the Fed-
eração Paulista de Futebol (2014 – Now) and member of the Board of directors of the Medical Committee of
the Confederação Brasileira de Futebol CBF (2014- Now). Also he is the Chairman of the FIFA Center of Excel-
lence of the UNIFESP. He is a current reviewer of Arthroscopy Journal, American Journal of Sports Medicine,
Revista Brasileira de Ortopedia. Moises is a professor of the Post-graduation program in Translational Surgery
and published 10 books, 183 articles in scientific journal, oriented 28 master degree, 16 PhD candidates and
2 post PhD.
Constantino de Campos Gustavo, Dr., MD, PhD
University of Campinas (UNICAMP) Department of Orthopedics
Campinas, Brazil
PhD at University of São Paulo (USP), Coordinator of UNICAMP’s musculosketelat tissue
bank, Knee surgeon at Campinas’s State University (UNICAMP) – Department of Ops,
Fellowship at Lyon’s School of knee surgery – Lyon, France, Postgraduate in osteometa-
bolic diseases at University of São Paulo (USP), Active member of Brazilian Society of
Orthopedics and Traumatology (SBOT), Brazilian Society of Knee Surgery (SBCJ) and
Brazilian intra-articular therapy studies association (ABETI)& J O I N T P R E S E R VA T I O N S O C I E T Y REGENERATION & SOCIETY
I N T E R N AT I O N A L FA C U L T Y International Cartilage Regeneration & Joint Preservation Society International Cartilage Regeneration
& Joint Preservation Society 19
Demange Marco, Dr., PhD.
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I N T E R N AT I O N A L C A R T I L A G E
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J O I N T P R E S E R VAT I O N I N T E R N AT I O N A L C A R T I L A G E J O I N T P R E S E R VAT I O N
University of São Paulo Orthopedics Department Sao Paulo, Brazil
R E G E N E R AT I O N SOCIETY R E G E N E R AT I O N SOCIETY
Assistant Professor of Orthopedic Surgery, University of São Paulo – Brazil, Chief of Knee
Surgery Division, Hospital das Clínicas – FMUSP, Private Practice at HCor – SP – Brazil,
Medical Degree – Unicamp – State University of Campinas – Brazil, Orthopaedic Train-
ing – University of São Paulo – Brazil, Knee Surgery Training – University of São Paulo
– Brazil Master of Science (M.Sc.) – University of São O N SOPaulo – Brazil, Ph.D. – University of
I NT ERN ATI O N A L CA RTI L AG E REG EN ER ATI O N I N T ERN AT I O N A L C A RT I L AG E R EG EN ER AT I O N
& J O I N T PR ES ERVAT I O N S O C I E T Y
& J O I NT PRESERVATI CI E T Y
São Paulo – Brazil, Post Doctoral Fellowship – Harvard Medical School – Brigham and
Women’s Hospital – Cartilage Repair Center – Boston – USA, Post Doctoral Fellowship –
Hospital for Special Surgery – NY – USA, Memberships: SBOT (Sociedade Brasileira de
Ortopedia e Traumatologia), SBCJ, SLARD, ISAKOS, International Affiliate Member – AAOS. ECFMG
International Certi-
Cartilage Regeneration
&
fied (U.S. – Educational Committee for Foreign Medical Graduates) INTERNATIONAL CARTI L AGE REGEN ER ATIO N
Joint Preservation Society
& J O I N T P R ES E RVAT I O N S O C I E T Y
Farr Jack, MD, MD
Cartilage Restoration Center of Indiana OrthoIndy Greenwood,
United States of America
Jack Farr received his undergraduate degree in biological engineering from Rose Hul-
man Institute of Technology in 1975, where he also was awarded an honorary doctor-
ate of biological engineering. He earned his medical degree from Indiana University
in 1979. He completed his orthopedic surgery residency at Indiana University Medical
Center in 1986. Dr. Farr has a subspecialty practice in knee and cartilage restoration.
His numerous appointments and affiliations include a voluntary clinical full professor-
ship in orthopedic surgery at Indiana University Medical Center, a board position with
the Cartilage Research Foundation, the International Cartilage Repair Society general board (Meetings and
Education Committee Chair) and Patellofemoral Foundation vice president. For more information, please go
to www.Cartilage Restoration.org. As a leader in U.S. cartilage restoration advances, Dr. Farr has written
numerous articles, book chapters and has completed and edited two cartilage books published in 2013. He
serves as associate editor for the journals Cartilage and American Journal of Orthopedics. For a full listing of
publications, please visit www.Cartilage Restoration.org. He lectures both nationally and internationally and
participates in several ongoing articular and meniscal cartilage clinical trials. He also was a design surgeon
for a meniscal allograft transplant system and two knee patellofemoral osteotomy systems. For patients with
knee changes too far advanced for restoration, Dr. Farr worked as a design surgeon for a current partial knee
replacement system (Sigma High Performance Partial Knee Replacement). Dr. Farr is actively affiliated with
the OrthoIndy Hospital and Community Hospital South. He is a member of the American Academy of Ortho-
paedic Surgeons, the American Orthopaedic Society of Sports Medicine, Arthroscopy Association of North
America, the International Cartilage Repair Society, International Patellofemoral Study Group, International
Society of Arthroscopy, Knee Surgery & Orthopaedic Sports Medicine and the European Society of Sports
Traumatology, Knee Surgery & Arthroscopy.
Gomoll Andreas, Ass. Prof., MD
Hospital for Special Surgery New York, United States of America
Born and raised in Germany, Dr. Gomoll attended Ludwig-Maximilians-Medical School
in Munich prior to spending 2 years at Brigham and Womens Hospital as a research
fellow. He then completed his residency training at the Harvard Combined Orthopaedic
Residency Program in Boston, MA, and a Sports Medicine Fellowship at Rush Univer-
sity in Chicago, IL. After his return to Boston, he joined the Cartilage Repair Center at
Brigham and Womens Hospital, where he rose to Associate Professor of Orthopaedic
Surgery, Harvard Medical School, and Director of the Orthopedic Program, BWH Cen-
ter for Regenerative Medicine. He moved his practice to the Hospital for Special Surgery
in 2018. He specializes in joint preservation and biologic knee reconstruction, such as cartilage repair, menis-
cal transplantation and osteotomy. His main research interests are clinical outcome studies of existing, as well
as the investigation of new cartilage repair procedures.I N T E R N AT I O N A L FA C U L T Y
Gracitelli Guilherme, Dr., Phd
Federal University of Sao Paolo Sao Paulo, Brazil
Graduated from Medical School – Federal University of São Paulo in 2007. Orthopedic
and Traumatology Residency at Department of Orthopedic and Traumatology of Federal
University of Sao Paulo 2009-2011. Fellowship in Knee Reconstruction and Arthroscopy
at Hospital Sao Paulo- Federal University of São Paulo in 2012. Member of knee group
at Federal University of São Paulo, member of the Brazilian Knee society. Current posi-
tion: Research fellow at The Scripps Research Institute (San Diego-USA) and visiting fel-
low at the University of California San Diego.
Krause Marcelo, Prof.
ITORK – Instituto de Traumatologia e Ortopedia Romeu Krause, Recife, Brazil
Professor of Traumatology and Orthopedic Surgery at UNINASSAU / Pernambuco –
Brazil, Staff of Knee Surgery and Shoulder and Elbow Surgery Division at ITORK / PE –
Brazil, Private Practice at ITORK – SP – Brazil, Medical Degree – UFPE – State University
of Pernambuco – Brazil, Orthopaedic Training – University of São Paulo – Brazil, Sport
Medicine, Knee Surgery and Shoulde and Elbow Training – University of São Paulo –
Brazil, Memberships: SBOT (Sociedade Brasileira de Ortopedia e Traumatologia), SBCJ,
SLARD, SBCOC
Lüring Christian, Prof., Dr. Med
Klinikum Dortmund Dortmund, Germany
Rosemberg Laercio, MD PhD,
Einstein Hospital, Sao Paulo, Brazil
Born in Sao Paulo, attended University of Sao Paulo Medical School. Residency in the
same institution was visitor fellowship for NYU, Emory , UCSF and HUP. Dr Laercio was
part of the first group to work with MRI in Latin America, in Hospital Albert Einstein Sao
Paulo , Brazil. He works at Hospital Albert Einstein and at Institute of Orthopaedic of
Hospital das Clinicas FMUSP where he started the service of Radiology and Interven-
tional Radiology in Orthopaedics. He works in close collaboration with Orthopaedic
surgeons that are involved in Cartilage Implants and repair.& J O I N T P R E S E R VA T I O N S O C I E T Y REGENERATION & SOCIETY
I N T E R N AT I O N A L FA C U L T Y International Cartilage Regeneration & Joint Preservation Society International Cartilage Regeneration
& Joint Preservation Society 21
Skaf Abdalla, Dr., MD
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J O I N T P R E S E R VAT I O N I N T E R N AT I O N A L C A R T I L A G E J O I N T P R E S E R VAT I O N
Hospital do Coração Sao Paulo, Brazil
R E G E N E R AT I O N SOCIETY R E G E N E R AT I O N SOCIETY
Chefe do departamento de diagnóstico por imagem do HCor (Hospital do Coração)
– São Paulo, Diretor médico da Teleimagem; Radiologista responsável pelo setor de
tomografia e Ressonância da clinica ALTA., Diretor da CAECIM – Centro de Aper-
feiçoamento e Educação em Imagem Médica; Membro titular do Colégio Brasileiro de
Radiologia e associado das sociedades & Americana e CIFrancesa de Radiologia; Research
I NT ERN ATI O N A L CA RTI L AG E REG EN ER ATI O N I N T ERN AT I O N A L C A RT I L AG E R EG EN ER AT I O N
& J O I N T PR ES ERVAT I O N S O C I E T Y
J O I NT PRESERVATI O N SO ETY
fellow na Universidade da Califórnia, San Diego (1999 – 2000); Médico-assistente
estrangeiro dos Hospitais de Paris (1997- 1998); Clinical fellow no Hospital Cochin e
Pitié-Salpetriere – Paris (1998 – 1999).
International Cartilage Regeneration
INTERNATIONAL CARTI L AGE REGEN ER ATIO N
&
& J O I N T P R ES E RVAT I O N S O C I E T Y Joint Preservation Society
Strickland Sabrina, Ass. Prof., MD
Hospital for Special Surgery Orthopedics New York City, United
States of America
Sabrina Strickland is board-certified in Sports Medicine and Orthopaedic Surgery at
Hospital for Special Surgery (HSS), where she specializes in surgery of the knee and
shoulder. Currently, Dr. Strickland is an Associate Professor of Orthopaedic Surgery at
HSS and Weill Cornell Medical College. Dr. Strickland is a co-founder along with col-
league Dr. Beth Shubin Stein of the HSS Patellofemoral Center. This center was created
to addresses the current lack of formalized research into patellofemoral disorders, treat-
ments and outcomes. The center focuses on clinical outcome studies that evaluate current
surgical techniques and improve patient outcomes as well as develop new ones. A comprehensive approach
is taken to investigating patient outcomes in a variety of patellofemoral disorders and treatment procedures.
By utilizing a combination of prospective, retrospective, and biomechanical studies, our group assesses the
efficacy of current procedures and improves upon them to develop even better treatment options. The Patel-
lofemoral Center is also focused on conducting collaborative research efforts with other institutions in the form
of multi-center studies, in order to maximize the quality and power of patellofemoral patient data available.
The comprehensive research efforts of the Patellofemoral Center play a critical role in improving the quality of
life of the many patients suffering from knee pain and instability.
Tambascia Rafael, Prof.
Instituto Wilson Mello Campinas, Jd. Santa Genebra , Brazil
DSc student at the Surgery Postgraduate Program at Unicamp – State University of
Campinas – Brazil, MSc from the Medical School of Ribeirão Preto – University of São
Paulo/ Brazil, Physiotherapist at The Wilson Mello Institute – Campinas/SP, Degree in
Physical Therapy from Unesp – State University of São Paulo/Campus Marília/SP, Mem-
ber of Physio&Science Group, Professor of Post Graduate Degree courses at the Facul-
dades Inspirar/MS and Universidade Barão de Mauá/SP, Post graduated in Orthopae-
dic and Traumatology at Unicamp – State University of Campinas – Brazil, Fellowship
at Guildford Physiotherapy Sports Centre – Sydney/AUS, Certificated in Spinal Manual
Therapy – Sydney/ AUS, Clinical interests are in degenerative and sports knee disorders and Orthopaedic
Sports MedicineI N T E R N AT I O N A L FA C U L T Y
Tirico Luis, Dr., M.D.
University of São Paulo - Medical School Orthopedic and
Traumatology Sao Paulo, Brazil
Luis Tirico is an Orthopedic Surgeon in São Paulo, Brazil. Born and raised in Brazil, he
received his medical degree from the University of São Paulo Medical School in 2003.
He worked as an attending physician in the Brazilian Army in 2004 and completed his
residency in Orthopedics in 2007 in the Orthopedic and Traumatology Department –
Hospital das Clinicas – University of São Paulo Medical School. In 2008 he finished his
fellowship in Knee Surgery in University of São Paulo and did a shortterm fellowship
with Dr. William Bugbee at Scripps Clinic, Green and Anderson Hospital in San Diego
CA in 2010. Since then, he has developed and been responsible for the Fresh Osteochondral Allograft pro-
gram in Knee Surgery at the Orthopedic and Traumatology Department, University of São Paulo,
Brazil. He was awarded the ICRS – Zimmer Scholarship Programme in 2012, spending time with Dr. Tom
Minas and Dr. Andreas Gomoll in Boston, MA. In 2015 he completed his Doctor of Medicine thesis entitled
“Protocol of procurement, processing and transplantation of fresh osteochondral allografts in the knee joint”
from the University of São Paulo, Brazil. In 2017 he was awarded by ICRS with the Lars Peterson Travelling
Fellowship representing the epitome of education and international partnership through thought leaders in
cartilage repair. His main clinical and research interests are cartilage repair procedures in knee surgery.
Uchoa de Rezende Marcia, Dr., MD, PhD
São Paulo, Brazil
Márcia Uchoa de Rezende is head of the Osteometabolic Group at the Instituto de
Ortopedia e Traumatologia do Hospital das Clínicas da Faculade de Medicina da
Universidade de São Paulo (IOTHC-FMUSP). Graduated from medical school (FMUSP)
in 1988, Member of the Brazilian Orthopedic Society (SBOT) since 1992. Overseas fel-
lowship at Duke University in 1995. Masters in 1996 and PhD in 2000 both at FMUSP.
Member of the board of directors of the Brazilian Knee Society since 2001. President of
the Brazilian Knee Society in 2009 and 2010. Post-doc in orthopedics in 2015. Heads
a program for education and conservative treatment of knee osteoarthritis.
Zaslav Kenneth, Prof., MD
Ortho Virginia Sports Medicine and Cartilage Restoration Center
Richmond, United States of America
Ken Zaslav is an Orthopaedic Surgeon and the founding director of Advanced Ortho-
paedic Centres: Sports Medicine and Cartilage Regeneration Centres, in Richmond,
Virginia in the U.S.A. He is a Clinical Professor of Orthopaedic Surgery at Virginia Com-
monwealth University and has published and lectured worldwide on Cartilage Repair,
and non-operative treatments for Articular Cartilage injury over the past 10 years. Dr.
Zaslav performed the first Articular Cartilage Transplant in Virginia in 1996 and since
then articular cartilage has been his prime clinical research interest. He has been a fel-
low of the ICRS since 1999 and has served on its Executive Committee and Board of Directors. He was the
president of the ICRS from 2016-2018. He is a member of the AOSSM, AAOS and AANA and has served on
its research, education and membership committees. He has spoken as an invited speaker at The FDA’s Cel-
lular, Tissue and Gene Therapies Advisory Committee meeting and was the lead author of The STAR Study of
Articular Cartilage repair published in AJSM in 2009. He serves on the Scientific Advisory Boards of several
Biologics companies in the United States and Israel and has previously served as The Chief Science Officer
of The Virginia Bio-commercialization Center at Virginia Commonwealth University and now serves on The
Board of Directors of The Virginia Life Science Investment Fund. He has been the Company Physician for The
Richmond Ballet for the past 20 years.& J O I N T P R E S E R VA T I O N S O C I E T Y REGENERATION & SOCIETY
International Cartilage Regeneration & Joint Preservation Society International Cartilage Regeneration
& Joint Preservation Society 23
I N T E R N AT I O N A L C A R T I L A G E
R E G E N E R AT I O N & J O I N T P R E S E R VAT I O N
SOCIETY
I N T E R N AT I O N A L C A R T I L A G E
R E G E N E R AT I O N & J O I N T P R E S E R VAT I O N
SOCIETY
I NT ERN ATI O N A L CA RTI L AG E REG EN ER ATI O N I N T ERN AT I O N A L C A RT I L AG E R EG EN ER AT I O N
& J O I N T PR ES ERVAT I O N S O C I E T Y
& J O I NT PRESERVATI O N SO CI E T Y
The ICRS is the Main Forum for International Collaboration
in Cartilaginous Tissue Research & Joint Preservation
INTERNATIONAL CARTI L AGE REGEN ER ATIO N
& J O I N T P R ES E RVAT I O N S O C I E T Y
International Cartilage Regeneration
&
Joint Preservation Society
Recognizing that there is a continuum from cartilage injury to degenerative joint disease we bring
together basic scientists, clinical researchers, physicians, other healthcare providers and members of
industry, engaged or interested in the field of articular biology, its genetic basis and regenerative medi-
cine. We seek to improve our patients´ quality of life, decrease their disability and reduce the impact of
degenerative joint disease on healthcare systems worldwide by preserving joints and maintaining func-
tion.” The Society has currently 1300 active members from 65 countries.
The purpose of ICRS is charitable: The society envisages the scientific research and the exchange of
knowledge among physicians, scientists, patients and researchers of the industry in the field of Cartila-
ge Regeneration and Joint Preservation. To serve its purpose, the society organizes international con-
gresses and events, publishes journals and provides a universal internet platform.
Join ICRS Now! Benefits for ICRS Members
• 4 Issues of the official ICRS Journal Cartilage, published by SAGE
• Highly reduced registration fees for all ICRS educational events
• Eligibility for ICRS Scholarships
• Eligibility for ICRS Travelling Fellowships
• Access to the “Member Only” section of the ICRS Website (incl. Membership
Database and access to the Cartilage Knowledge Database, Electronic Posters,
Abstracts and selected Symposia presentations)
• Free advertising of your cartilage meeting /course in the ICRS Newsletter
The Annual Membership Fees are: and online event calendar
Ordinary Members: € 220.00
Junior Members: € 100.00
Corporate Members: € 3000.00
Join ICRS online at
Our Mission
www.cartilage.org Advancing Science & Education of the Prevention
office@cartilage.org & Treatment of Cartilage Disease Worldwide
International Cartilage Regeneration
& Joint Preservation SocietyYou can also read
