SDC/GAVI WEBINAR - TOWARD EQUITABLE ACCESS TO SARS- COV-2 VACCINES FOR ALL - DANIEL THORNTON, SENIOR ADVISER, GAVI 17 FEBRUARY 2021 - TOWARD ...
←
→
Page content transcription
If your browser does not render page correctly, please read the page content below
Classified as Internal
SDC/Gavi Webinar - Toward equitable access to SARS-
CoV-2 vaccines for all
Daniel Thornton, Senior Adviser, Gavi
17 February 2021
www.gavi.org
Classified as Internal
The pandemic poses the greatest threat to global health security
in a century
2.4m+
deaths 110m+
cases
“we estimate
that faster progress on
ending the health crisis
will raise global income
cumulatively by $9 trillion
over 2020–25, with benefits
for all countries, including
around $4 trillion for
advanced economies.”
IMF’s Chief Economist
2
Classified as Internal
The COVAX pillar is the engine to deliver on the ACT-A objectives by
accelerating fair and equitable access to vaccines at scale
Access to COVID-19 Tools Accelerator (ACT-A) “COVAX” pillar Key players
Therapeutics Diagnostics Vaccine
partnership partnership partnership
Development & Procurement Policy and
Manufacturing and delivery at allocation
Therapeutics Find CEPI Led by CEPI, scale Led by WHO
Accelerator (co-convener) (co-convener) with industry Led by Gavi
(co-convener)
WHO
UNITAID Global fund Gavi, the vaccine
(co-convener) (co-convener) alliance COVAX Coordination Meeting (CCM)
(co-convener)
Health systems strengthening
3
Classified as Internal
4
Progress on Agreements with Suppliers
To date, the COVAX Facility has signed
SII deal gives AMC92 agreements with six candidates…
economies access to
vaccines licensed Deal with SII to provide doses for AMC92
from Novavax and economies
SII / AstraZeneca collaboration announced on
AstraZeneca Aug 7, 20201
SII / Novavax collaboration announced on Sep
29, 20202
Deal with AstraZeneca announced on Dec 17,
20203
Deal with Pfizer / BioNTech announced on
Jan. 22, 20215
MoU with Janssen / J&J announced on Dec
17, 20203
Statement of Intent with
Sanofi / GSK, announced on October 28,
20204
1. Gavi press release COVAX is actively negotiating deals with
2. Gavi press release
3. Gavi press release several candidates, with further
4. Gavi press release announcements expected in the near-term
5. Gavi press release
Speed, Scale, Access 5
Classified as Internal
COVAX AMC: a reality underway
US$ 2.6 billion raised, and an additional US$ 4 billion from the US
At least 1.3 billion doses secured in 2021
Half a billion roll out scheduled in first half of 2021
The priority is to procure and roll out the vaccines in low- and middle-income
countries
To reach our goal we need at least an additional US$ 2 billion by Q2 2021.
6
Classified as Internal
The COVAX AMC needs additional funding of $2bn by Q2 2021
• $2.5bn + $4bn from US pledged
Contribution (US$ Donor Contribution (US$ Donor Governments Contribution
Donor Governments
million) Goverments million) and other donors (US$ million)
Australia 58 Netherlands 35
Austria 2.9 Other sovereign donors
New Zealand 11
(including Belgium,
Canada 246
Norway 140 Bhutan, Colombia,
European Commission 117
Denmark, Estonia, 117
Qatar 10 Greece, Iceland,
France 117 Luxembourg, Monaco,
Saudi Arabia 153
Singapore)
Germany 121
Spain 59
Italy 103
Sweden 22 Bill & Melinda Gates
Japan 200 156
Foundation
Switzerland 22
Korea 10
Kuwait 10 United Kingdom 735 Private Sector 85
7
*Team Europe (European Commission/EIB) has also pledged 400m EUR in guarantees
Classified as Internal CAVEATS
COVAX AMC global supply forecast Contracts: Some of the supply included in the
projections are linked to deals that are already
concluded and some are currently being
by AMC-eligible participants - 2021 negotiated. Terms are subject to change.
Candidate attrition: Some candidates are still in
clinical development. If they do not achieve
positive clinical trial outcomes (safety and
AS PER 2021-01-19 efficacy) and regulatory approval, these volumes
will not be procured by COVAX.
PRELIMINARY AND SUBJECT TO ASSUMPTIONS
Regulatory approval: Supply timing will depend
on regulatory success and timelines, including
COVAX AMC Available Supply, Cumulative, Mn doses, 20211 reviews of individual batches (“batch release”).
1,785
Manufacturing: In many cases, manufacturing is
AMC yet to reach full scale. Manufacturing productivity
1,460 will be influenced by multiple factors, which will in
turn influence volume and timing of supply.
1,175 Delivery: Timing of delivery will depend on
Further
volumes various factors, including local regulatory
940
to become approval, country readiness, logistics,
785 available indemnification and liability in place, in-country
in 2022, distribution etc.
630
subject to Funding availability: Total potential supply is
Corresponding to supply
465 funding shown; procurement of these doses will depend
availability, regulatory approvals
may cause delays to deliveries
availability on COVAX AMC fundraising, AMC92 cost-
235 sharing beyond donor-funded doses, and the final
170
105 prices and volumes of doses allocated to AMC92.
Allocation: These supply forecasts reflect a
preliminary distribution of doses based on each
Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec Early
participant’s share of available supply pro rata by
2022 demand and are to be treated as indicative. Final
1
timing and volumes will be determined by the
Supply refers to volumes of vaccine available from the manufacturer. Timing of forecasts is based on anticipated release of doses from
8 WHO Allocation Mechanism.
manufacturers. Volumes for expected single-dose regimen vaccine candidates doubled to ensure comparability across vaccine candidates.
8
Volumes have been rounded to the nearest 5M (except for those smaller than 5M), and so totals may not equal sum of segments.Classified as Internal
COVAX AMC global supply forecast by region - 2021
AMC91-supported
countries and
number of doses,
to end of 2021
[ Design note: Marshall Islands no longer included (version 15 Feb 2021) ]Classified as Internal
Breakdown of AMC expenditures
10Classified as Internal
Additional donor pledges needed ahead of March 2021 to exercise
firm orders
11Preparing for delivery
Thank you Communications workshop
Classified as Internal
Building the AMC: the path to equitable access
Country Engagement
92 low- and middle- COVAX announces
& Vaccine Deals
More than 150 COVAX Publicly announced
income economies additional deals to access
countries engaged in announces COVAX deals, to
eligible to get access to promising COVID-19
COVID-19 vaccine secure
COVID-19 vaccines vaccine candidates; signed deal
global access facility additional
through Gavi COVAX plans global rollout with Pfizer for
AMC 40m doses doses in 2021
starting Q1 2021
The COVAX AMC
Resource Mobilisation
Gavi launches the Over US $2 billion Gavi welcomes needs at least an
innovative financing raised to support US contribution additional US $2
mechanism COVAX equitable access to of $4 billion in billion by June 2021
AMC as the first COVID vaccines supplemental
building block of with additional US$ to deliver equitable
funding for
the COVAX Facility. 5 billion needed in procurement and access to COVID-19
$500m raised. 2021 delivery. vaccines
Vaccine
Summit
COVAX AMC
Global Goal:
Advocacy Key Moment
EC hosts UNGA
Coronavirus Unite for Our
Global Future
Response UK Hosts
Pledging Global G20 Call Paris Peace
Event Vaccine to Action Forum
Summit
4 June Today June 2021
15 2020 [Progress to date]
2021
Note: conceptual visual, not shown to scaleClassified as Internal
The Campaign ahead: cascading moments to build up
momentum
Phase I: Securing AMC initial Support Phase II: Outreach to donors – securing at least US$ 2 billion Phase III: define 2022 scenarios
• Adjust plans after taking stock of
Munich the results achieved with Phase II
World Economic
Security
Forum Annual
Conference
Meeting "The • Close coordination with the ACT-A
Weekly CSOs (TBC) Africa CEO platform
Launch AMC Great Reset"
June 2020 engagement Forum – Gavi Vaccine Technology
GVS meeting event Summit
G7 • Clear, consistent, and mutually
London
Early reinforcing messaging
summit
Media brief Vaccine Summit
Coronavirus Global Media brief TBC 2021 • Engage with key journalists and
Response Media brief IO Launch media outlets in targeted markets
2021
Global Goal Unite our Paris peace G7 Summit
future forum
• Publishing compelling digital
G20 health World content across multiple channels to
working group Immunization
G20 G20 finance and enlisting influential champions to
Opening Week WB Springs
UNGA
meeting
Dev extend its public reach, including in
Event tracks
G20
G20 finance
AMC eligible countries.
AMC Donor meeting Vaccines launch
African and Dev
tracks In country
Union Summit 2021
G20 EU - World Health Summit
International Chamber of
WEF Annual meeting Health Summit Regional meeting
Commerce (ICC)
Singapore Kampala
roundtable breakfast
AMC Country Leadership Engagement
Close coordination with ACT-A
platform
Building momentum and securing pledges G7/ G20 Engagement
US$ 2.5 billion
Targeted media engagement
16 Clear, consistent, and mutually
16 CSO Advocacy and Campaign reinforcing messagingYou can also read
