BioMAT 2019 08 - May 2019 Weimar, Germany - Program - Deutsche Gesellschaft für ...
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Program
5th Euro
BioMAT 2019
European Symposium and Exhibition
on Biomaterials and Related Areas
08. - 09. May 2019
Weimar, Germany
https://biomat2019.dgm.de
1
Table of Content Welcome Note
Based on the huge success of the previous four Euro BioMAT Symposia 2011 in Jena and in
2013, 2015 and 2017 in Weimar this international conference will be held every two years
in the Jena-Weimar region.
The symposium Euro BioMAT 2019, 08.-09. May 2019, addresses the growing interest of
science and industry in the different aspects of the creation, characterization, testing and
application of biomaterials and closely related areas. The motivation is not only the recent
scientific progress and new challenges of this exciting, strongly interdisciplinary field of
science and engineering. Materials scientists, physicists, chemists, biologists in industrial
R&D as well as medical professionals are increasingly facing situations, where materials are
confronted with high performance requirements and a challenging biological environment
at the same time.
Much of the growth in the area of biomaterials emerged in the USA and Asia over the last
years, but Europe is gaining ground with a fast and steady growth in this field. The German
Materials Society (DGM) and its panel of experts in biomaterials address these developments
with the Euro BioMAT 2019 in Weimar. Euro BioMAT 2019 will present and discuss the
current state of progress and novel trends in the development, characterization, application,
testing and modelling of biomaterials in basic science and industry. In addition, this
symposium will bring together experts in closely related areas, such as biomimetics,
General Information 4
biomineralization and biopolymers.
The Venue 5
Program Committee 6 The organizers at the DGM feel a need to serve the European biomaterials community
beyond other European and world biomaterials congresses with a compact two-day
Topics 8
meeting which brings together fascinating science and inspiring people in a delightful
Program Overview 10 setting in historic Weimar in the very heart of Europe. The program of the Euro BioMAT
Program Wednesday 12 2019 will comprise several invited plenary lectures as well as oal and poster presentations.
Program Wednesday Oral Poster Session 23
We look forward to see you in Weimar 2019!
Poster Session 26
Program Thursday 30
List of Authors and Participants 38
List of Exhibitors & Sponsors 42
DGM Panel of Experts for Biomaterials 44
The Otto Schott Institute of Materials Research/
Chair of Materials Science 45
Tourist Information & Sightseeing-Tour Weimar 46
Klaus D. Jandt Thomas F. Keller
Chairman Vice Chairman
Friedrich Schiller University Jena, Germany DESY Hamburg, Germany
2 3
General Information The Venue
Date Conference Fees Poster Award Location of the Ramada by Distances from the RAMADA
08.-09. May 2019 Young Researchers up to A prize for the best poster will be Wyndham BY WYNDHAM Hotel Weimar
30 years awarded by a jury. The winner
Conference Chairs DGM members 200 EUR will be announced and awarded The hotel is only a few Goethe‘s Home: 6 km
Klaus D. Jandt Non-members 240 EUR on Thursday 09. May 2019 at kilometers from Weimar city Bauhaus Museum: 10 km
Chairman 09:00 a.m. center. You can reach Weimar City Palace and
Friedrich Schiller University Jena, Expert Researchers 31-45 years City and its numerous sights in Marstall (stables): 10 km
Germany DGM members 300 EUR Poster Award Sponsor: just 10 minutes by car and 20 Buchenwald Monument: 16 km
Non-members 360 EUR minutes by public transport. Park at the River Ilm: 5 km
Thomas F. Keller Bus number 6 stops just Deutsches Nationaltheater
Vice Chairman Professionals University 20 meters from the hotel. The (German National Theater): 7 km
DESY Hamburg, Germany DGM members 500 EUR hotel‘s proximity to the A4 Anna Amalia Library: 7 km
Non-members 600 EUR Abstracts motorway is ideal for those Park caves: 6 km
Congress Office All abstracts are on display on arriving by car. Jakobskirche: 8 km
Deutsche Gesellschaft für Industry the conference website and will Herderkirche: 7.5 km
Materialkunde e.V. DGM members 650 EUR remain online after the Directions to the Hotel Belvedere Palace: 6 km
c/o INVENTUM GmbH Non-members 780 EUR conference. Tiefurt Mansion: 10 km
Alexia Ploetz Arrival to the hotel by car: Erfurt and Jena: 30 km
Marie-Curie-Straße 11-17 Lunch List of Participants A4 motorway: Take the Weimar
53757 Sankt Augustin, Germany Lunch is included in the confe- An updated List of Participants is exit (junction 49); follow the B85
biomat@dgm.de rence fees and will be served on availble on the conference towards Rudolstadt. Then follow
Wednesday and Thursday in the homepage. the Hotelroute Süd (South hotel
Conference Website hotel restaurant. route). At the roundabout in
https://biomat2019.dgm.de Legefeld, take the first exit. The
Coffee Breaks Hotel Weimar is situated on the
Conference Language Coffee and refreshments will be left after approx. 200m.
The official congress served during the official breaks.
language will be English Arrival to the hotel by public
Oral Poster Session transport from the railway
Conference Venue The oral poster session will be station:
RAMADA BY WYNDHAM held on Wednesday Plenty of taxis are available at
Weimar 08. May 2019 starting at 18:40 the railway station. The journey
Kastanienallee 1 in the lecture Room Goethe I. from the station to the hotel
99428 Weimar costs around 20.- Euro. There is
Germany Poster Discussion Evening also the option of taking the city
T +49 (0) 30 610819461 Poster authors will have the bus number 6 towards Legefeld.
F +49 (0) 351 21777499 opportunity to discuss their sub- The transfer takes around 20-25
reservation.dresden@ ject with delegates and answer minutes. Current bus timetables
gchhotelgroup.com questions in front of their poster can be requested when making
https://www.ramada-hotel- after the oral poster session. your reservation.
weimar.com/en Snacks and beverages will be
offered.
Internet Access
Internet vouchers for
conference visitors can be
purchased at the hotel reception
There is free internet access for
the hotel guests.
4 5
Program Committee
Aldo R. Kaiyong Cai Gabriela Ciapetti David Eglin Matthias Epple Helder A. Santos Thomas Scheibel Norman Stark Bo Su Wojciech
Boccaccini Chongqing Rizzoli AO Research Ruhr-University University of University of Straub Medical University of Swieszkowski
University of University, China Orthopaedic Institute Davos, Duisburg- Helsinki, Finland Bayreuth, AG, Wangs, Bristol, UK Warsaw
Erlangen- Institute, Switzerland Essen, Germany Switzerland University of
Nürnberg, Bologna, Italy Germany Technology,
Germany Poland
Jack Ferrcane Ehud Gazit Maria-Pau Dirk Grijpma Klaus D. Jandt Annelie-Martina Frank Witte Fergal J. O'Brien
Oregon Health Tel Aviv Ginebra University of Friedrich Schiller Weinberg Charité Berlin, Royal College
& Science Uni- University, Technical Univer- Twente, The University Jena, Medizinische Germany of Surgreons
versity, Portland, Israel sity of Catalonia, Netherlands Germany Universität Graz, Ireland RCSI,
USA Spain Austria Dublin, Ireland
Adrian Keller Thomas F. Keller Petra Kluger Veikko Linko João F. Mano
Paderborn Uni- Deutsches Reutlingen Aalto University, University of
versity, Germany Elektronen- University, Finland Minho,
Synchrotron Germany Braga, Portugal
DESY, Hamburg,
Germany
Giovanni Alvaro Mata Werner E.G. Bradley Nelson Kurosch Rezwan,
Marletta Queen Mary Müller ETH Zürich, University of
University of University of Johannes Switzerland Bremen,
Catania, Italy London, UK Gutenberg Germany
University Mainz,
Germany
6 7
KONGRESS
Topics UND
FACHAUSSTELLUNG
FÜR INNOVATIVE WERKSTOFFE,
The following subjects will be discussed: VERFAHREN UND ANWENDUNGEN
A Structure and properties of biomaterials
• A1 Bio-nano materials
•
•
A2 Bioactive materials, bioglass and calciumphosphates
A3 Biodegradable materials
SYMPOSIUM
• A4 Bioinspired materials / biomimetic materials ZUR WERKSTOFFWOCHE
• A5 Biological materials and biomineralization
• A6 Computational biomaterials science
BIOMATERIALIEN
• A7 Hydrogels and biobased & synthethic polymers
• A8 Imaging of biomaterials
B Biological response to biomaterials
•
•
B1 Biofilms & antimicrobial biomaterials
B2 Biocompatibility
DONNERSTAG & FREITAG
• B3 Biointerfaces and microenvironments 19.–20. SEPTEMBER 2019
• B4 Clinical performance and microenvironments
• B5 Multi-functional biomaterials
SYMPOSIUMSORGANISATOREN
C Biomaterials applications
PROF. DR. KLAUS D. JANDT
• C1 Current and future challenges for the MedTech industry
Friedrich-Schiller-Universität Jena
• C2 Dental materials
Leiter Lehrstuhl für Materialwissenschaften
• C3 Drug and gene delivery
• C4 Innovation in fabrication including 3D printing / additive manufacturing /
biofabrication of biomaterials
• C5 Responsive and smart biomaterials PROF. DR.-ING. HABIL. ALDO R. BOCCACCINI
• C6 Tissue engineering / regenerative medicine Friedrich-Alexander-Universität Erlangen-Nürnberg
• C7 Materials for ophthalmology Leiter Lehrstuhl Biomaterialien
D Biopolymer-based biomaterials
• D1 Special Session „Biopolymer-based biomaterials“ PROF. DR. THOMAS SCHEIBEL
Universität Bayreuth
Leiter Lehrstuhl Biomaterialien
PD DR.-ING. THOMAS F. KELLER
Deutsches Elektronen-Synchrotron, Hamburg
8 Erfahrung . Kompetenz . Wissen 9
WWW.WERKSTOFFWOCHE.DE
Deutsche Gesellschaft für Materialkunde e.V.
Program Overview Wednesday Program Overview Thursday
Wednesday Thursday
08:00 Poster Mounting and Registration Room Goethe I
08:00 Plenary Lecture: J. Groll
Room Goethe I
09:00 Opening Address: K.D. Jandt 08:30 Plenary Lecture: L.E. Bertassoni
09:15 Plenary Lecture: L. Adler-Abramovich 09:00 Announcement of the Poster Award Winner
09:45 Plenary Lecture: C. Rieker 09:10 Coffee Break
10:15 Coffee Break Room Goethe III Room Bach Room Schiller
Room Goethe III Room Bach Room Schiller 09:40 A5: Biological materials A2: Bioactive materials, C2: Dental materials
and biomineralization bioglass and
11:00 A7: Hydrogels and B3: Biointerfaces and C4: Innovation in fabri-
biobased & synthetic microenvironments cation including 3D calciumphosphates
polymers printing/
additive manufacturing/ 11:00 Coffee Break
biofabrication of
biomaterials 11:30 A4: Bioinspired materials A2: Bioactive materials, C6: Tissue engineering/
/ biomimetic materials bioglass and regenerative medicine
calciumphosphates
13:00 Lunch Break
13:10 Lunch Break
14:10 A7: Hydrogels and B3: Biointerfaces and D1: Special Session:
biobased & synthetic microenvironments Biopolymer-based Room Goethe I
polymers biomaterials 14:20 Round Table Discussion
Room Goethe III Room Bach Room Schiller
15:30 C3: Drug and gene
15:40 A4: Bioinspired materials A3: Biodegradable C6: Tissue engineering/
delivery
/ biomimetic materials materials regenerative medicine
16:30 Coffee Break
Room Goethe I
17:00 C3: Drug and gene B1: Biofilms & C8: SFB 1278 16:40 Closing Remarks
delivery antimicrobial Polytarget - Polymer
biomaterials Nanoparticles for Drug
Delivery
17:40 A8: Imaging of bioma-
terials
Room Goethe I
18:40 Oral Poster Session
Foyer of the conference hotel
20:00 Poster Discussion Evening
10 11
Program Wednesday 08:00 - 09:45 Program Wednesday 09:45 - 11:00
Wednesday Plenary Lecture
08:00 Poster Mounting and Registration 09:45 Metal-on-metal bearings, where is the scandal?
C. Rieker, Zimmer Biomet EMEA (Switzerland)
Room Goethe I
09:00 Opening Address
K.D. Jandt, Chairman of the conference, Friedrich Schiller University Jena (Germany)
Plenary Lecture Metal-on-metal bearings for total hip arthroplasties have an 80-year long clinical history
Chair K.D. Jandt, Chairman of the conference, Friedrich Schiller University Jena (Germany) with a first implantation done in England in 1938. With a few early exceptions, the alloy
used for these metal-on-metal bearings was always a cobalt-chromium-molybdenum
09:15 Learning from Nature to Form New Organic alloy, which is a very common alloy in modern orthopaedic technology.
Materials for Tissue Regeneration
L. Adler-Abramovich, Tel Aviv University (Israel) Based on the good clinical results seen in the early 80’s with some patients with a
metal-on-metal bearing implanted in the 60’s, a research development was conducted by
Sulzer Medizinaltechnik in Switzerland to better understand the tribology of these
bearings. Two major improvements were made: (1) development of a wrought high
carbon cobalt-chromium-molybdenum alloy and (2) optimization of the bearing
The high demand for scaffolds capable of inducing tissue regeneration using minimally clearance. These two improvements allow Allo Pro and Protek to re-introduce small
invasive techniques prompts the need for the development of new biomaterials. Herein, diameter metal-on-metal bearings in the early 90’s under the tradename Metasul™.
we investigate the ability of different compositions of short self-assembling peptides and
polysaccharides to form extracellular mimicking scaffolds for tissue regeneration. For this As the clinical results of these small diameter metal-on-metal bearings were excellent,
aim, we used various polysaccharides such as hyaluronic acid, a major component of they were used as a basis for the development of large diameter metal-on-metal bearings,
the extracellular matrix and alginate, a natural anionic biopolymer derived from brown especially for resurfacing prostheses. The research conducted in the late 90’s
seaweeds.These polysaccharides were incorporated with short peptides and amino acids demonstrated that large diameter metal-on-metal bearings have definitively an excellent
building blocks that can form ordered assemblies such as nanotubes, nanospheres, and in-vitro tribological behaviour based on partial or full film lubrication. These good in-vitro
3D-hydrogels with unique biological and physical properties. However, the control over results lead to the market introduction of these large diameter metal-on-metal bearings,
the physical properties of the structure, including mechanical strength, degradation not only for resurfacing prostheses, but also for total hip arthroplasties. These bearings
profile and injectability has remained challenging. In molecular self-assembly, the physical were rapidly “adopted” by orthopaedic surgeons for their multiple advantages (stability
properties of the formed assemblies are directed by the inherent characteristics of the and range of motion). Their early clinical results were promising, but a small number of
composing building blocks. Moreover, molecular co-assembly at varied stoichiometry patients developed some adverse biological reactions with these bearings.
substantially increases the structural and functional diversity of the formed assemblies,
allowing to tailor both their architecture as well as their physical properties. This plenary talk will analyse the reasons for these adverse biological reactions and
In line with polymer chemistry paradigms, we applied a supramolecular polymer co-as- investigate the patients’ consequences, the media and legal implications of these large
sembly methodology to modulate the physical properties of hydrogel scaffolds. Using this diameter metal-on-metal bearings.
approach, we developed a new peptide-based hydrogel with extraordinary rigidity, deri-
ved from a synergism between two different short peptides that were co-assembled. Due 10:15 Coffee Break
to its high stiffness, this hydrogel may serve as a scaffold for bone regeneration. Also, its
tuneable mechanical properties may affect stem cells differentiation to different lineages
as well. The co-assembly approach together with the incorporation of bone ceramics
further enabled us to design a composite organic-inorganic scaffold with high affinity to
hydroxyapatite, allowing bone tissue regeneration.
This work provides a conceptual framework for the utilization of co-assembly strategies to
push the limits of nanostructures physical properties obtained through self-assembly.
12 13
Program Wednesday 11:00 - 11:40 Program Wednesday 11:40 - 12:20
Room Goethe III Room Bach Room Schiller Room Goethe III Room Bach Room Schiller
A7: Hydrogels and B3: Biointerfaces and C4: Innovation in A7: Hydrogels and B3: Biointerfaces and C4: Innovation in fab-
biobased & synthetic microenvironments fabrication including 3D biobased & synthetic microenvironments rication including 3D
polymers printing/ polymers (cont.) printing/
additive manufacturing/ (cont.) additive manufacturing/
biofabrication of biofabrication of
biomaterials biomaterials
(cont.)
Chair K.D. Jandt T.F. Keller A. Dorner-Reisel,
11:40 Hydrogel-based surfaces In vitro short-time 3D printed PLA for
Friedrich Schiller University Deutsches Elektronen-Syn- Schmalkalden University of
for stem cell process method for the multipurpose
Jena (Germany) chrotron DESY, Hamburg Applied Sciences
engineering determination of applications in chemistry
(Germany) (Germany)
M. Gepp (Sp)1; A. Serr2; long-term stability of and biology
B. Fischer1; A. Vahtrik2; implant materials M. Schneider (Sp)1;
11:00 Functional materials for Bone marrow analogs 3D Printing of Porous
J.C. Neubauer1; N. Wegner (Sp)1; A. Taubert1
applications in the brain for studying stem cell Scaffold Designed for
H. Zimmermann2 R. Scholz1; M. Klein1; 1
University of Potsdam
C. Selhuber-Unkel (Sp)1 niches in health and Biomedical Implant 1
Fraunhofer Project Center M. Knyazeva1; F. Walther1 (Germany)
1
Kiel University (Germany) disease Development
for Stem Cell Process 1
TU Dortmund University
C. Lee-Thedieck (Sp)1; F. Shalchy (Sp)1; C. Lovell2;
Engineering, Würzburg (Germany)
A. Raic1; D. Kratzer1; A. Bhaskar1
(Germany); 2Fraunhofer
S. Zippel1;
1
University of Southamp-
Institute for Biomedical
A. Ludwig-Husemann1 ton (United Kingdom);
Engineering, Sulzbach
1
Leibniz University
2
Lucideon ltd., STOKE-ON-
(Germany)
Hannover (Germany) TRENT (United Kingdom)
12:00 Microstructure, Creating standardized 3D printing of bone
11:20 3D Environments for Interfacing of human Biomaterial properties mechanical and wells on solid substitute materials
Cells - Adaptable stem cell derived to protect cells in 3D tribological biomaterials for based on capillary
Microchannels in neurons with vertically bioprinting performance of PVA biocompatibility testing suspensions
Biofunctionalized aligned nanowires as E. Courtial (Sp)1; hydrogels for cartilage C. Ißleib (Sp)1; E. Preuße1; D. Menne (Sp)1;
Hydrogels function of nanowire C.A. Marquette1; E. Petiot1 replacement S. Kurz1; J. Spohn1 N. Willenbacher1
K. Siemsen (Sp)1; length, diameter and 1
Université Claude Bernard A. Oliveira (Sp)1; O. Seidi2; 1
Fraunhofer Institute for 1
Karlsruhe Institute of
S. Gutekunst1; S. Huth1; array pitch Lyon1, Villeurbanne R. Colaço1; A. Serro3 Ceramic Technologies and Technology (KIT) (Germany)
H.C. Trinh1; F. Rasch1; J. Harberts (Sp)1; (France) 1
Universidade de Lisboa Systems IKTS, Dresden
Y.K. Mishra1; R. Adelung1; R. Zierold1; C. Fendler1; (Portugal); (Germany)
C. Selhuber-Unkel1 J. Teuber1; W. Kim2; 2
École supérieure
1
Kiel University (Germany) A. Fontcuberta i Morral2; d‘ingénieurs de Paris-Est
R.H. Blick1 Créteil (France);
1
Universität Hamburg 3
Instituto Universitário Egas
(Germany); Moniz, Lisboa (Portugal)
2
École Polytechnique
Fedérale de Lausanne
(Switzerland)
14 15
Program Wednesday 12:20 - 14:10 Program Wednesday 14:10 - 15:10
Room Goethe III Room Bach Room Schiller
A7: Hydrogels and B3: Biointerfaces and C4: Innovation in fab- Room Goethe III Room Bach Room Schiller
biobased & synthetic microenvironments rication including 3D A7: Hydrogels and B3: Biointerfaces and D1: Special Session:
polymers (cont.) printing/ biobased & synthetic microenvironments Biopolymer-based
(cont.) additive manufacturing/ polymers (cont.) biomaterials
biofabrication of (cont.)
biomaterials
(cont.) Chair A. Keller
Paderborn University
12:20 New approaches in Corrosion at modular Properties of (Germany)
designable 3D hydrogel taper junctions in lightweight fibrous
scaffolds via anatomical shoulder structures made by a 14:10 Hyaluronan-based Nanostructured Surfa- Hierarchical Assembly of
Polyoxazoline prosthesis - a retrieval foam forming technique hydrogels as ophthalmic ce-Induced Changes in DNA Filaments with
T. Wloka (Sp)1; study S. Burke (Sp)1 drug carriers Protein Adsorption and Designer Elastic
M. Gottschaldt1; M. Crackau (Sp)1; 1
Trinity College Dublin T. Walter (Sp)1; Implications on Platelet Properties
T. Wloka1; S. Czich2; N. Märtens1; T. Halle1; (Ireland) M. Schnabelrauch1; Adhesion and Activation W. Pfeifer (Sp)1
K. Liefeith3 C.H. Lohmann1; R. Wyrwa1; C. Altmann1 I. Firkowska-Boden (Sp)1; 1
University of Duisburg-
1
Friedrich Schiller University J. Bertrand1
1
INNOVENT e. V., Jena C. Helbing1; X. Zhang1; Essen (UDE) (Germany)
Jena (Germany); 1
Otto von Guericke (Germany) K.D. Jandt1
2
University of Bayreuth, University Magdeburg
1
Friedrich Schiller University
Heilbad Heiligenstadt (Germany) Jena (Germany)
(Germany); 14:30 A biocompatible Tuning Protein DNA-functionalization
3
Institute for Bioprocessing reversible thermal Orientation for Bioactive of surfaces based on
and Analytical actuator with tunable Surfaces recombinant spider silk
Measurement Techniques transition temperature G. Marletta (Sp)1; proteins
(iba), Heilbad Heiligenstadt N. Wilharm (Sp)1; G.M.L. Messina1; M. Humenik (Sp)1;
(Germany) T. Fischer2; W. Knolle1; N. Tuccitto1; G. Li Destri1; T. Scheibel1
12:40 Trends, challenges, and Tribological behaviour F. Ott2; A. Beck-Sickinger2; C. Mazzuca2; A. Palleschi2 1
University of Bayreuth
future advancements in of wet bovine bone with M. Zink2; S. Mayr1 1
University of Catania (Germany)
ophthalmological respect to a metallic
1
Leibniz Institute of (Italy);
materials and devices implant: effects of load, Surface Engineering (IOM), 2
University of Roma Tor
I. Firkowska-Boden (Sp)1 sliding speed, material Leipzig (Germany); 2Leipzig Vergata (Italy)
1
Friedrich Schiller University and sliding orientation University (Germany)
Jena (Germany) J. Nohava (Sp)1; C. Voutat2; 14:50 Mechanically stable Two-Photon-Lithogra- Plant-Derived Scaffolds
O. Marzieh2; P. Zysset2 sulfobetainc Hydrogels - phy and Atomic Layer for Tissue Engineering
1
Anton Paar TriTec SA, A candidate for Deposition: A Tailor-Ma- Applications
Peseux (Switzerland); biomedical application de Route for Artificial 3D B. Garipcan (Sp)1;
2
University of Bern R. Ihlenburg (Sp)1; Scaffold-Mediated Neu- M. Toker1; S. Rostami1;
(Switzerland) A.F. Thünemann2; ronal Network Studies M. Kesici2; Ö. Gül2;
13:00 Lunch Break K. Brademann-Jock2; C. Fendler (Sp)1; Ö. Kocatürk1
K. Saalwaechter3; R. Zierold1; C. Denker2; 1
Bogazici University,
A. Taubert1 J. Harberts1; G. Loers3; Istanbul (Turkey);
1
University of Potsdam M. Münzenberg2; 2
Bilgi University, Istanbul
(Germany); 2Bundesanstalt R.H. Blick1 (Turkey)
für Materialforschung und 1
Universität Hamburg
-prüfung (BAM), Berlin (Germany);
(Germany); 2
University of Greifswald
3
Martin-Luther-University (Germany); 3University Me-
Halle-Wittenberg, Halle dical Center Hamburg-Ep-
a.d. Saale (Germany) pendorf (UKE) (Germany)
16 17
Program Wednesday 15:10 - 15:50 Program Wednesday 15:50 - 17:00
Room Goethe III Room Bach Room Schiller Room Goethe III Room Bach Room Schiller
C3: Drug and gene B3: Biointerfaces and D1: Special Session: C3: Drug and gene B3: Biointerfaces and D1: Special Session:
delivery microenvironments Biopolymer-based delivery microenvironments Biopolymer-based
(cont.) biomaterials (cont.) (cont.) biomaterials
(cont.) (cont.)
Chair B. Garipcan, Bogazici
15:50 Functionalization of Nanoconfinement Enzymes as architects of
University, Istanbul
Polymer Fibers for and Santsetsukon-like surface structures
(Turkey)
Neuronal Regeneration Nanocrawling Govern O. Strube (Sp)1
15:10 Adhesive drug Bioactive cellulose I. Wille (Sp)1; N. Schmidt1; Fibrinogen Dynamics 1
Paderborn University
delivery systems for non-woven materials P. Behrens1; J. Schulze2; and Self-Assembly on (Germany)
bone healing based on using natural A. Warnecke2 Nanostructured
polyelectrolyte complex ingredients
1
Leibniz University Polymeric Surfaces
nanoparticles K. Römhild (Sp)1; Hannover (Germany); I. Firkowska-Boden (Sp)1;
M. Müller (Sp)1 B. Kosan1; F. Meister1;
2
Hannover Medical School X. Zhang1; M.M.L. Arras2;
1
Leibniz Institute of M. Gericke2; T. Heinze2; (MHH) (Germany) M.J. Kastantin3;
Polymer Research Dresden T. Müller3; J. Müller3; C. Helbing1; A. Özogul1;
(Germany) B. Giese3 E. Gnecco1;
1
Thuringian Institute D.K. Schwartz3; K.D. Jandt1
of Textile and Plastics
1
Friedrich Schiller University
Research Rudolstadt e. V. Jena (Germany);
(Germany);
2
Oak Ridge National
2
Friedrich Schiller University Laboratory (United States);
Jena (Germany);
3
University of Colorado
3
SYNLAB Analytics & Boulder (United States)
Services Germany GmbH, 16:10 Mitotane Loaded Low-temperature-
Jena (Germany) Poly(2-oxazoline) sterilization method
15:30 Inorganic nanoparticle TiO2 Nanotube Arrays as Programmable Micelles: Physico- for thermal sensitive
mediated delivery of platform for long-term pH-responsive DNA Chemical biomaterials
siRNA organotypic culture and nanocapsule for loading, Characterization and D. Voigt (Sp)1; E. Klüver1;
K. Besecke (Sp)1; mechanical encapsulation, and Cytotoxicity Studies in M. Meyer1
P. Behrens1; characterization of displaying of cargo 2D & 3D in Vitro Models. 1
Forschungsinstitut für
P. Dillschneider2; retina explants – from H. Ijäs (Sp)1 M. Haider (Sp)1; Leder und
M. Stiesch2; A. Hoffmann2; imaging to mechanical 1
University of Jyväskylä, J. Schreiner2; S. Kendl2; Kunststoffbahnen gGmbH
H. Hartwig2 response Espoo (Finland) M. Kroiss2; R. Luxenhofer1 (FILK), Freiberg (Germany)
1
Leibniz University S. Friebe (Sp)1; S. Weigel1;
1
University of Würzburg
Hannover (Germany); M. Francke1; M. Zink1; (Germany);
2
Hannover Medical School S. Mayr1
2
University Hospital of
(MHH) (Germany) 1
Leipzig University Würzburg (Germany)
(Germany)
16:30 Coffee Break
18 19Program Wednesday 17:00 - 17:40 Program Wednesday 17:40 - 18:20
Room Bach Room Schiller Room Goethe III Room Bach Room Schiller
B1: Biofilms & C8: SFB 1278 A8: Imaging of B1: Biofilms & anti- C8: SFB 1278
antimicrobial Polytarget - Polymer biomaterials microbial biomaterials: Polytarget - Polymer
biomaterials Nanoparticles for Drug Biofilms & antimicrobial Nanoparticles for Drug
Delivery biomaterials Delivery based
(cont.) Biomaterials
Chair I. Firkowska-Boden, C. Helbing
Friedrich Schiller University Friedrich Schiller University (cont.)
Jena (Germany) Jena (Germany) Chair N.N.
17:00 Electro-chemical Formulation and 17:40 Angle-resolved light Adhesion of E. coli on Synthesis and
Inactivation of Bacteria characterization of scattering as versatile nano-rough titanium Formulation of
on Titanium Implants by drug-loaded characterization tool for surfaces – image and Functional Polymeric
Boron-doped Diamond nanoparticles using surfaces and biological genetic analyses Nanoparticles based on
Coating conventional and new cells N. Stefani (Sp)1; Poly(methacrylate)s
S. Rosiwal (Sp)1; biodegradable polymers N. Felde (Sp)1; M. Schürmann2; P. Klemm (Sp)1;
H. Ghanem1; M. Stiesch2; B. Shkodra-Pula (Sp)1; A.-S. Munser, A. Gärtner; V. Schroeckh1; S. Dietrich1; T. Yildirim1; U.S. Schubert1;
A. Burkovski1; A. Vollrath1; C. Kretzer1; S. Schröder1; T. Wolf1; K.D. Jandt2; U.S. Schubert1
M. Schuman1; A. Labitzke1 I. Nischang1; O. Werz1; A. Tünnermann1 M.T. Figge1; 1
Friedrich Schiller University
1
Friedrich-Alexander- U.S. Schubert1 1
Fraunhofer Institute for G. Panagiotou1; Jena (Germany)
Universität Erlangen- 1
Friedrich Schiller University Applied Optics and A.A. Brakhage1
Nürnberg (FAU) (Germany); Jena (Germany) Precision Engineering IOF, 1
Leibniz Institute for
2
Hannover Medical School Jena (Germany) Natural Product Research
(MHH) (Germany) and Infection Biology e. V.,
Jena (Germany);
17:20 The Antimicrobial Eliminating the third 2
Friedrich Schiller University
Actions of Supported variable: The effect of
Jena (Germany);
Silver Nanoparticles crystallinity of polyester
H. Cao (Sp)1 based nanoparticles for 18:00 3D characterization of Nano-rough titanium Polyesteramide
1
Shanghai Institute of drug delivery, isolated scaffolds for culturing surfaces created by wet Nanoparticles with
Ceramics, Chinese from the influence of and tissue engineering alkaline etching and PVD “stealth polymer” shell
Academy of Sciences the hydrophilic/ A. Cecilia (Sp)1; M. Schürmann (Sp)1; M. Dirauf (Sp)1;
(China) hydrophobic balance V. Weinhardt2; B. Zhao1; J. Bossert1; I. Muljajew1; C. Weber1;
K. Scheuer (Sp)1; R. Hofmann1; K.D. Jandt1 U.S. Schubert1
K.D. Jandt1; M. Zuber1; F. Gruhl1; 1
Friedrich Schiller University 1
Friedrich Schiller University
U.S. Schubert1; C. Weber1; A. Bäcker1; Jena (Germany) Jena (Germany)
D. Bandelli1; C. Helbing1; R. Surmenev³;
J. Alex1 M. Surmeneva³;
1
Friedrich Schiller University N. Aadepu¹;
Jena (Germany) S. Shkarina³;
T. Baumbach¹
¹Karlsruhe Institute of
Technology (KIT),
Eggenstein-Leopoldshafen
(Germany);
²Heidelberg University
(Germany);
³Tomsk Polytechnic
University (Russia)
20 21Program Wednesday 18:20 - 18:40 Oral Poster Session Wednesday 18:40 - 20:00
Room Goethe III Room Schiller Room Goethe I
A8: Imaging of C8: SFB 1278 18:40 Oral poster session
biomaterials Polytarget - Polymer Chair T.F. Keller
(cont.) Nanoparticles for Drug Deutsches Elektronen-Synchrotron DESY, Hamburg (Germany)
Delivery based
Biomaterials C4-33 Effect of surface processing on roughness, wettability and cytotoxicity of carbon
(cont.) fiber-reinforced polyetheretherketone (PEEK) composite fabricated by fused
deposition modeling
18:20 Perspectives for Imaging Hydrodynamic and Light
X. Han (Sp)1; C. Yang2; S. Spintzyk1; L. Scheideler1; D. Li2; J. Geis-Gerstorfer1; F. Rupp1
of Biomaterials utilizing Scattering Study of 1
University Hospital Tübingen (Germany); 2Xi’an Jiaotong University, Xi‘an (China)
highly brilliant X-ray Carboxymethyl
sources Celluloses B1-23 Characterisation of bactericidal titanium surfaces using electron microscopy
T.F. Keller (Sp)1 M. Grube (Sp)1; J. Jenkins (Sp)1; S. Kulkarni2; T.F. Keller2; A. Nobbs1; P. Verkade1; B. Su1;
1
Deutsches Elektronen- U.S. Schubert1;
1
University of Bristol (United Kingdom); 2Deutsches Elektronen-Synchrotron DESY,
Synchrotron DESY, I. Nischang1 Hamburg (Germany)
Hamburg (Germany) 1
Friedrich Schiller University C4-1 Fabrication of Alginate/Honey Scaffolds by 3D bio-printing and studying their
Jena (Germany) Mechanical, Morphological and Cell Viability Properties for in-situ Skin Tissue
Engineering Applications
S. Datta (Sp)1; V. Vyas1; R. Barua1; R. Sarkar1; A. Barui1; A. RoyChowdhury1; P. Datta1
1
Indian Institute of Engineering Science and Technology (IIEST), West Bengal (India)
A1-6 Parvovirus B19 virus-like particles as platform for the development of
biomaterials
I. Bustos-Jaimes (Sp)1; M. Cayetano-Cruz1; C.E. Segovia-Trinidad1
1
National Autonomous University of Mexico (Mexico)
A1-18 The Influence of Surface Nanopatterns with varying Periodicities on Protein
adsorption
Y. Yang (Sp)1; M. Yu1; G. Grundmeier1; A. Keller1
1
Paderborn University (Germany)
A4-72 Opaque, Translucent and Transparent Flower Petals
T. Arakawa (Sp)1; O. Karthaus1
1
Chitose Institute of Science and Technology (Japan)
B3-38 Impact of Surface Morphology and Net Charge of Spider Silk based Materials on
Interactions with Human Blood Components
S. Lentz (Sp)1; A.C.G. Weiss2; H. Herold1; M. Faria2; Q. Besford2; C. Borkner1; C.-S. Ang2;
E.J. Crampin2; E. Müller3; M. Rottmar3; F. Caruso2; T. Scheibel1
1
University of Bayreuth (Germany); 2The University of Melbourne (Australia);
3
EMPA Swiss Federal Laboratories for Materials Science and Technology, St. Gallen
(Switzerland)
B1-75 Modulation of Bacteria on Titanium Surfaces via Nanotopography and
Antimicrobial Peptides
M. Eales (Sp)1; A. Nobbs1; W. Briscoe1; M. Ryadnov2; T.F. Keller3; B. Su1
1
University of Bristol (United Kingdom);
2
National Physical Laboratory (NPL), Teddington, London (United Kingdom);
3
Deutsches Elektronen-Synchrotron DESY, Hamburg (Germany)
A3-78 Degradable hybrid polymers for tissue engineering
J. Schwaiger (Sp)1; S. Nique1; H. Wolter1
1
Fraunhofer Institute for Silicate Research ISC, Würzburg (Germany)
22 23Oral Poster Session Wednesday 18:40 - 20:00 Oral Poster Session Wednesday 18:40 - 20:00
Oral poster session (cont.) Oral poster session (cont.)
B1-141 Antibacterial functionalization of plasma-chemical oxidized titanium surfaces C7-153 Diclofenac and moxifloxacin simultaneous delivery from intraocular lenses for
S. Kranz (Sp)1; A. Guellmar1; J. Schmidt2; S. Tonndorf-Martini1; M. Diefenbeck3; endophthalmitis prophylaxis
B. Sigusch1 A. Serro (Sp)1; B. Saramago2; A. Topete1
1
University Hospital Jena (Germany); 2INNOVENT e.V., Jena (Germany); 1
Instituto Universitário Egas Moniz, Lisbon (Portugal); 2Instituto Superior Técnico, Lisbon
3
Schön Klinik Hamburg-Eilbek (Germany) (Portugal)
A7-93 Thermal crosslinking of hydrophilic polymers using polyperoxides A2-161 Optimization of a calcium phosphate based bone cement formulation
S. Borova (Sp)1; R. Luxenhofer1; V. Tokarev2 R. Colaço (Sp)1; M. Reis1; N. Ribeiro2; L. Figueiredo3; A. Pimenta3; A. Serro1
1
University of Würzburg (Germany); 2Lviv Polytechnic National University (Ukraine) 1
Instituto Superior Técnico, Lisbon (Portugal); 2Hospital dos Lusiadas, Lisbon (Portugal);
3
Bioceramed, Lisbon (Portugal)
A4-81 Poly(peptoid)s: Peptidomimetics as potential Biomaterials
C. Schlutt (Sp)1; R. Luxenhofer1 A2-60 Nanostructured bone apatite-like thin films for bone prostheses
1
University of Würzburg (Germany) G. Graziani (Sp)1; M. De Carolis1; M. Bianchi1; E. Sassoni2; M. Berni1; A. Gambardella1;
N. Baldini1
A1-111 A Nanoscaled Hybrid Coating for Neuronal Electrodes: Nanoporous Silica NPs 1
Rizzoli Orthopaedic Institute, Bologna (Italy); 2Università di Bologna (Italy)
Embodied into Nanoporous Platinum
T. Pinkvos (Sp)1; J. Schulze2; V. Hagemann1; H.A. Schulze1; D.P. Warwas1; S. Zailskas1; A2-177 Low-dose BMP-2 enhances the bone-forming effects of an injectable, PLGA
A. Schierz1; A. Mohmeyer1; M. Jahns1; K.D. Kreisköther1; H.C. Schwarz1; A. Warnecke2; fiber-reinforced, brushite-forming cement in sheep lumbar osteopenia defects
P. Behrens1 F. Gunnella (Sp)1; E. Kunisch1; S. Maenz2; B. Illerhaus3; M. Bungartz4; O. Brinkmann4;
1
Leibniz University Hannover (Germany); 2Hannover Medical School (MHH) (Germany) J. Bossert5; R.W. Kinne1
1
University Hospital Jena, Eisenberg (Germany); 2Aesculap AG, Tuttlingen (Germany);
C2-116 Drug Delivery from Nanoporous Titania Coatings for Dental Application 3
Bundesanstalt für Materialforschung und -prüfung (BAM), Berlin (Germany);
S. Zailskas (Sp)1; P. Abendroth1; M. Stiesch2; P. Behrens1 4
Waldkrankenhaus Rudolf Elle GmbH, Eisenberg (Germany);
1
Leibniz University Hannover (Germany); 2Hannover Medical School (MHH) (Germany) 5
Friedrich-Schiller-Universität Jena (Germany)
A3-119 Waste to resource: Biopolymer from industrial wastewater
A2-178 The PLGA fiber component of brushite-forming calcium phosphate cement
R. Nogueira (Sp)1; P. Tamang1
induces the osteogenic differentiation of human adipose tissue-derived stem cells
1
Leibniz University Hannover (Germany)
F. Gunnella (Sp)1; E. Kunisch1; S. Wagner1; F. Dees2; S. Maenz3; J. Bossert4; K.D. Jandt4;
A1-120 Divide and Comprehend: Separating the Effects of Hydrophobicity/ R.W. Kinne1
Hydrophilicity and Crystallinity on the Thermal Properties of Polyester Based 1
University Hospital Jena, Eisenberg (Germany);
Drug Delivery Systems 2
Alere Technologies GmbH, Jena (Germany); 3Aesculap AG, Tuttlingen (Germany);
K. Scheuer (Sp)1; K.D. Jandt1; U.S. Schubert1; C. Weber1; D. Bandelli1; J. Alex1; 4
Friedrich-Schiller-Universität Jena, Jena (Germany)
C. Helbing1
1
Friedrich Schiller University Jena (Germany) C6-134 Surface functionalization of nanofibers by plasma processing in Ar/CO2/C2H4
discharge
A2-122 Elastic Polymer-Coated Nano- and Macroporous Bioactive Glass-Composites for E. Permyakova (Sp)1; A. Manakhov1; P. Kiruhancev-Korneev1; N. Gloushankova2;
Bone Regeneration D. Shtansky1
M. Lietzow (Sp)1; K. Besecke1; R. Hinterding1; L. Burmeister2; A. Hoffmann2; 1
National University of Science and Technology MISiS, Moskau (Russia);
A. Kampmann2; M. Stiesch2; N. Ehlert1 2
N.N. Blokhin Russian Cancer Research Centre of RAMS, Moscow (Russia)
1
Leibniz University Hannover (Germany); 2Hannover Medical School (MHH) (Germany)
C6-130 Keratinocytes HaCaT Proliferation on a 3D-Printed Chitosan-Collagen Scaffold
E. Hermida (Sp)1; M. Pérez Recalde1; A. González Wusener1; J. Polenta1; A. Bolgiani2
1
National University of San Martin - UNSAM (Argentina); 2BIOMATTER S.A., Buenos Aires
(Argentina)
A7-133 Alginate/ silk fibroin-based hydrogels for vascularized tissue constructs
R. Singh (Sp)1; H. Genc1; T. Distler2; R. Detsch2; B. Dietel1; A.R. Boccaccini2; C. Alexiou1;
I. Cicha1
1
Universitätsklinikum Erlangen (Germany); 2Friedrich-Alexander-Universität
Erlangen-Nürnberg (FAU) (Germany)
24 25Poster Session Poster Session
Foyer of the conference hotel A7-89 Modification of bacterial cellulose to enhance anti-inflammatory wound dressing
properties
20:00 Poster discussion with snacks and drinks in the foyer of the lecture halls
U. Beekmann (Sp)1; P. Zahel1; B. Karl1; L. Schmölz1; S. Lorkowski1; O. Werz1;
poster evening barbecue
D. Fischer1; D. Kralisch1
1
Friedrich Schiller University Jena (Germany)
A1-99 Synthesis, solubility and optical activity of chiral
poly(2,4-disubstituted-2-oxazoline)s A7-147 Absolute Characterization of Synthetic Macromolecules used in Biomaterials
M. Yang (Sp)1 Science Applications
1
University of Würzburg (Germany) M. Grube (Sp)1; U.S. Schubert1; I. Nischang1
1
Friedrich Schiller University Jena (Germany)
A1-156 Cytotoxicity of gold nanorods and nanoribbons in context of biomedical
applications A8-115 Biodegradable thermoplastic materials for bimodal imaging containing the
M. Musielak (Sp)1; J. Patalas1; K. Rucinska1; J. Maksim1; A. Bos-Liedke1; A. Molinski1; mineral present in the human body
M. Kozak1 Z. Górecka (Sp)1; E. Choinska1; W. Swieszkowski1
1
Adam Mickiewicz University, Poznan (Poland) 1
Warsaw University of Technology (Poland)
A1-157 Preliminary studies of synthesis of gold nanoribbons using selected dicationic A8-175 Three-dimensional nanoscale X-ray computed
surfactants tomography for the visualisation of cells grown on fibrous scaffolds
J. Patalas (Sp)1; J. Maksim1; K. Rucinska1; M. Musielak1; A. Bos-Liedke1; A. Molinski1; J. Martins de Souza e Silva (Sp)1; C. Santos de Oliveira2; A. Trompetero González2;
Z. Pietralik1; M. Kozak1 T. Kürbitz3; T. Hedke4; C.E.H. Schmelzer4; R.B. Wehrspohn4
1
Adam Mickiewicz University, Poznan (Poland) 1
Martin-Luther-University Halle-Wittenberg (Germany);
2
Martin-Luther-Universität Halle-Wittenberg, Halle (Saale) (Germany);
A1-160 Ideas on improving the comparability of bio-nano data
³Anhalt University of Applied Science, Köthen (Germany);
H. Cao (Sp)1; X. Liu2; K.D. Jandt1 4
Fraunhofer Institute for Microstructure of Materials and Systems IMWS, Halle (Saale)
1
Friedrich Schiller University Jena (Germany);
(Germany)
2
Shanghai Institute of Ceramics, Chinese Academy of Sciences (China)
B1-90 Nano-rough titanium surfaces created by wet alkaline etching and PVD and their
A1-179 Investigating Dynamic Biological Processes with High-Speed, High-Resolution
influence on bacterial adhesion as well as protein adsorption
Correlative AFM-Light Microscopy
M. Schürmann (Sp)1; N. Stefani2; V. Schroeckh2; A.A. Brakhage2; J. Bossert1; K.D. Jandt1
O. Pabsch (Sp)1; T. Mueller1; H. Haschke1 1
Friedrich Schiller University Jena (Germany);
1
Bruker Nano GmbH, Berlin (Germany) 2
Leibniz Institute for Natural Product Research and Infection Biology, Jena (Germany)
A2-59 Dual-setting brushite-silica gel cements – Variations of the monomer precursors
B1-101 Effective strategies for the controlling and dealing with transmission pathway of
and tuning of the setting parameters
pathogens in air traffi
I. Holzmeister (Sp)1; J. Groll1; U. Gbureck1
C. Helbing (Sp)1; T. Dauben1; C. Dewald1; B. Zhao1; J. Bossert1; K.D. Jandt1
1
University Hospital of Würzburg (Germany) 1
Friedrich Schiller University Jena (Germany)
A2-165 Influence of Cu2+-doping in β-TCP on the hydration kinetics of brushite cement
B1-104 Nanostructured high-pressure laminate surfaces to reduce transmission pathways
investigated by Rietveld analysis and heat flow calorimetry
of pathogens in public transportation
K. Späth (Sp)1; K. Hurle1; F. Goetz-Neunhoeffer1
C. Helbing (Sp)1; T. Dauben1; K. Scheuer1; J. Bossert1; K.D. Jandt1
1
Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) (Germany) 1
Friedrich Schiller University Jena (Germany)
A3-31 Corrosion behaviour of potencially biodegradable ternary alloy Zn-Mg-Ca
B2-36 Cytotoxicity evaluation of biodegradable Zn-4Cu alloy using L929, Saos-2 and
J. Pinc (Sp)1; J. Capek1; J. Kubasek2; E. Jablonská2
TAg cell lines
1
Czech Academy of Sciences, Prague (Czech Republic);
P. Li (Sp)1; W. Zhang2; E. Schweizer1; J. Dai1; D. Alexander1; G. Wan2; J. Geis-Gerstorfer1;
2
University of Chemistry and Technology Prague (Czech Republic)
L. Scheideler1
A3-32 Biomineralization of Recombinant Spider Silk Films 1
University Hospital Tübingen (Germany);
V. Neubauer (Sp)1; T. Scheibel1 2
Southwest Jiaotong University, Chengdu (China)
1
University of Bayreuth (Germany)
B2-79 Influence of pulsed bias voltage on the tribological and morphological properties
A3-126 Improvements in PHB production by wild type Cupriavidus necator using of a-C coatings deposited by an anodic arc method
different feeding strategies I. Erdmann (Sp)1; F. Deuerler1; V. Buck2
E. Hermida (Sp)1; O. Yashchuk1; D. Noseda1; D. Nygaard1 1
University of Wuppertal (Germany); 2University of Duisburg-Essen (UDE) (Germany)
1
National University of San Martin - UNSAM (Argentina)
26 27Poster Session Poster Session
B2-183 Multi scale topography in titanium alloys by electron beam technique: influence C7-158 Diclofenac release from a silicon based hydrogel for contact lenses controlled by
on the tissue adhesion and bacterial contamination a layer-by-layer coating
F. Warchomicka (Sp)1; C. Ramskogler1; S. Ferraris2; A. Cochis3; L. Rimondini3; A. Serro (Sp)1; D. Silva2; H. Sousa3; H. Gil3; C. Alvarez-Lorenzo4; B. Saramago2
A. Weinberg4; S. Spriano2; C. Sommitsch1 1
Instituto Universitário Egas Moniz, Lisbon (Portugal);
1
Graz University of Technology (Austria); 2Politecnico di Torino (Italy); 2
Instituto Superior Técnico, Lisbon (Portugal);
3
Università del Piemonte Orientale, Novara (Italy); 4Medical University Graz (Austria) 3
Universidade de Coimbra (Portugal); 4Universidade de Santiago de Compostela (Portugal)
B3-35 Chairside plasma activation of encapsulated implants: how fast is it? D1-16 Durability analysis of the cryopreservation of DNA origami nanostructures
M. Garcia Chame (Sp)1; F. Rupp1; C. Diener2; J. Geis-Gerstorfer1 Y. Xin (Sp)1; C. Kielar1; X. Xu1; S. Zhu1; N.G. Gorin1; G. Grundmeier1; A. Keller1
1
University Hospital Tübingen (Germany); 1
Paderborn University (Germany)
2
Diener electronic GmbH + Co. KG, Ebhausen (Germany) D1-57 Effects of staple age on DNA origami nanostructure assembly and stability
B3-50 Novel QCM-D/microscopy set-up for real-time analysis of bacterial binding onto C. Kielar (Sp)1; X. Xu1; S. Zhu1; N.G. Gorin1; G. Grundmeier1; A. Keller1
biomaterial-coated sensors 1
Paderborn University (Germany)
Z. Xu (Sp)1; T. Reiner2; L. Scheideler1; S. Krajewski1; J. Geis-Gerstorfer1; F. Gehring2;
F. Rupp1
1
University Hospital Tübingen (Germany); 23T analytik, Tuttlingen (Germany)
B3-86 Analytical investigation of the influence of micro- and nanoplastic particles in
crop plants by electron microscopic imaging and spectroscopy
J. Wissler (Sp)1; D. Dierksen1
1
TESCAN GmbH, Dortmund (Germany)
C2-52 Influence of fluoride corrosion attack on the metal-porcelain bond strength of
TiCr20 compared to titanium
C. Schille (Sp)1; J. Geis-Gerstorfer1; T. Sawada2; S. Takemoto2
1
University Hospital Tübingen (Germany); 2Iwate Medical University (Japan)
C3-84 Bacterial nanocellulose loaded with frankincense extract as natural wound
dressing to treat local dermal inflammations
B. Karl (Sp)1; Y. Alkhatib1; U. Beekmann1; G. Blume2; D. Kralisch1; O. Werz¹;
S. Lorkowski1; D. Fischer1
1
Friedrich Schiller University Jena (Germany); 2Sopharcos, Steinau an der Straße (Germany)
C4-128 Characterization of 3D printed bioesorbable scaffolds for bone regeneration
E. Hermida (Sp)1; B. Aráoz1; T. Federico1; G. Gueron2; A. González Wusener1;
E. Vazquez2; A.R. Boccaccini3
1
National University of San Martin - UNSAM (Argentina);
2
University of Buenos Aires (Argentina);
3
Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) (Germany)
C6-98 Graded functionalization of polydopamine coated fiber mats as potential implant
for tendon-bone-transition
S. Oehmichen (Sp)1; S. Sydow1; A. Becker2; J. Sundermann1; H. Bunjes1; B. Glasmacher1;
H. Menzel1
1
TU Braunschweig (Germany); 2Leibniz University Hannover (Germany)
C6-138 Enhancing the functionalities of bioactive glass-based scaffolds by novel
polymeric coatings
L. Liverani (Sp)1; E. Christodoulou2; G.S. Theodorou2; S. Heid1; D. Patsiaoura2; D. Bikiaris2;
E. Kontonasaki2; A.R. Boccaccini1
1
Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) (Germany);
2
Aristotle University of Thessaloniki (Greece)
28 29Program Thursday 08:00 - 09:00 Program Thursday 09:00 - 10:20
Room Goethe I 09:00 Announcement of the Poster Award winner
Plenary Lectures K.D. Jandt, Chairman of the conference, Friedrich Schiller University Jena (Germany)
Chair N.N.
Poster Award Sponsor
08:00 Biofabrication – Chances, Challenges and Limits
J. Groll, University Hospital Wuerzburg (Germany)
09:10 Coffee Break
Room Goethe III Room Bach Room Schiller
A5: Biological materials A2: Bioactive materials, C2: Dental materials
and biomineralization bioglass and
Biofabrication is a young field of research that aims at the automated generation of calciumphosphates
hierarchical tissue-like structures from cells and materials through automated procedures Chair O. Karthaus R.W. Kinne N.N.
in Bioprinting or Bioassembly. This approach has the potential to overcome a number of Chitose Institute of Science University Hospital Jena,
classical challenges in relating to organization, personalized shape and mechanical and Technology (Japan) Eisenberg (Germany
integrity of generated constructs.
Although this has allowed achieving some remarkable early successes, it has recently 09:40 Human Aorta under Bioactive Glass Aging First Steps in Oral
become evident that the lack of variety in materials that can be formulated together with Tensile Stress and Its Impact on Biofilm Formation - The
cells for Bioprinting, so called Bioinks, is one major drawback for the complete field. S. Friebe (Sp)1; Sintering Interplay of Biopolymers
Mainly, such materials are hydrogels or hydrogel precursor formulations; however, J. Haunschild1; C. Etz1; L. Lefebvre (Sp)1; A. Mari2; in Adsorption Processes
alternative approaches both regarding materials and printing techniques have recently S. Mayr1 P.F. Menci2; on Dental Materials
been developed to extend this shortcoming. This contribution will give an introduction to 1
Leipzig University C. Charbonneau1; S. Ehnert (Sp)1
the field, critically review the current status, including examples of our recent work, and (Germany) L. De Nardo2 1
TU Kaiserslautern
also concern some of the current challenges. 1
National Research Council (Germany)
Canada, Boucherville
(Canada);
08:30 Digital Light Projection Stereolithography 2
Politecnico di Milano (Italy)
Bioprinting and Guided Mineralization of Microscale
Tissue Models to Study Stem Cell Differentiation and 10:00 Honeycomb films Beyond the shape Subtractive vs additive
Bone Tissue Engineering prepared by the breath control of manufacturing in the
L.E. Bertassoni, Oregon Health and Science University figure technique can be hydroxyapatite nanopar- production of Zirconia
(USA) used as templates for ticles: on the relevance pieces for dental
inorganic compounds of the relative amount applications
Fabrication of three-dimensional tissues with controlled microarchitectures has been O. Karthaus (Sp)1 of A. Branco (Sp)1; R. Silva2;
shown to enhance tissue functionality. Our group has been interested in developing
1
Chitose Institute of (01-10)_Ca-rich and M. Polido1;
3D bioprinting, biofabrication and materials chemistry-based technologies to enhance Science and Technology HA(01-10)_P-rich C. Figueiredo-Pina3;
our ability to regenerate tissues with controlled microarchitectures, physical properties (Japan) surfaces and related R. Colaço2; A. Serro1
and overall function. In this seminar, we will present novel SLA/DLP-based 3D printing impact on water and 1
Instituto Universitário Egas
methods to fabricate high-throughput screening platforms to probe mechanotransduction protein adsorption Moniz, Monte da Caparica
and geometry-controlled mechanisms of stem cell differentiation. Further, we will discuss P. Ivanchenko (Sp)1; (Portugal);
recent biomineralization methods that our lab has developed to engineer bone-like tissues F. Catalano1; P. Ugliengo1; 2
Instituto Superior Técnico,
with nanoscale precision. This novel method will be discussed in light of its ability to M. Iafisco2; G. Martra1; Lisbon (Portugal);
replicate the native bone vasculature, innervation, composition, and osteoinductive A. Tampieri2 3
Instituto Politécnico de
properties, as well as its ability of replicating the process of cancer invasion (metastasis)
1
University of Turin, Torino Setúbal (Portugal)
into bone. (Italy);
2
National Research Council
(CNR), Faenza (Italy)
30 31Program Thursday 10:20 - 11:30 Program Thursday 11:30 - 12:10
Room Goethe III Room Bach
Room Goethe III Room Bach Room Schiller
A5: Biological materials A2: Bioactive materials, C2: Dental materials
A4: Bioinspired A2: Bioactive materials, C6: Tissue engineering/
and biomineralization bioglass and (cont.)
materials/ bioglass and regenerative medicine
(cont.) calciumphosphates
biomimetic materials calciumphosphates
(cont.)
(cont.)
10:20 Structural Differences of Multifunctional nano- Chair W. E.G. Müller C. Lee-Thedieck,
Human and Yak Hair and macroporous Johannes Leibniz University
A. Müllner (Sp)1; bioactive Gutenberg University Hannover (Germany)
H. Peterlik1; glass-composites for Mainz, Germany
D. Brandhuber2 bone regeneration
1
University of Vienna N. Ehlert (Sp)1; M. Lietzow1; 11:30 Understanding bacterial Hydration mechanism 4D Printing Objects:
(Austria); J. Schaeske2; N. Stumpp2; interactions awith of an injectable apatite A New Approach
2
Less Is More Cosmetics M. Stiesch2; L. Burmeister2; nanostructured surfaces cement modified with Toward Complex Tissue
GmbH, Vienna (Austria) A. Hoffmann2; M. Ishak (Sp)1; A. Nobbs1; sodium phytate Engineering
S. Gniesmer2; W. Briscoe1; S. Kulkarni1; K. Hurle (Sp)1; C. Devillard (Sp)1;
A. Kampmann2; T.F. Keller2; B. Su1 J. Weichhold2; U. Gbureck2; C. Mandon1;
K. Besecke1 1
University of Bristol F. Goetz-Neunhoeffer1 C.A. Marquette1
1
Leibniz University (United Kingdom); 1
Friedrich-Alexander- 1
3D.FAB, Villeurbanne
Hannover (Germany); 2
Deutsches Elektronen- Universität Erlangen- (France)
2
Hannover Medical School Synchrotron DESY, Nürnberg (FAU) (Germany);
(MHH) (Germany) Hamburg (Germany) 2
University of Würzburg,
Wuerzburg (Germany)
10:40 Effect of calcium
phosphate 11:50 Self-Assembled Plasma Improved mechanical DLC coated CoCrMo
reinforcement on Protein Hybrid properties of femural parts for knee
Gelatin-Chitosan for Nanofibers brushite-forming calcium prostheses and
developing a 3D porous C. Helbing (Sp)1; phosphate cements by biomimetic
composite scaffold for T. Deckert-Gaudig2; polymer fiber micro-pattering with
bone tissue engineering- G. Wei3; K. Scheuer1; reinforcement femto-second laser
a comparative study K.D. Jandt1 I. Firkowska-Boden (Sp)1; technique
K. Maji (Sp)1 1
Friedrich Schiller University K.D. Jandt1 A. Dorner-Reisel (Sp)1;
1
National Institute of Jena (Germany); 1
Friedrich Schiller University S. Weißmantel2
Technology (NIT), Rourkela 2
Leibniz Institute of Jena (Germany) 1
Schmalkalden University
(India) Photonic Technology, Jena of Applied Sciences
(Germany); (Germany);
11:00 Coffee Break 3
University of Bremen 2
Laserinstitut Mittweida
(Germany) (Germany)
32 33Program Thursday 12:10 - 12:30 Program Thursday 12:30 - 14:20
Room Goethe III Room Bach Room Schiller Room Goethe III Room Bach Room Schiller
A4: Bioinspired A2: Bioactive materials, C6: Tissue engineering/ A4: Bioinspired A2: Bioactive materials, C6: Tissue engineering/
materials/ bioglass and regenerative medicine materials/ bioglass and regenerative medicine
biomimetic materials calciumphosphates (cont.) biomimetic materials calciumphosphates (cont.)
(cont.) (cont.) (cont.) (cont.)
12:10 Fibrinogen + Salt The GDF5 mutant BB-1 Scaffolds with 12:30 Blood plasma like Alkaline Nanofibersflakes for 3D
= 3D-nanofibrous may be superior to GDF5 Multiscale Mechanical material for phosphatase (ALP) tissue engineering
scaffolds: A new self for the enhancement Properties for multiphoton activity of the ATDC-5 A. Heilmann (Sp)1;
assembly method of bone formation Endochondral Healing of polymerization cell line following K. Tobias2; N. Michler2;
D. Brüggemann (Sp)1; induced by an injectable, Large Bone Defects L. Zeußel (Sp)1; exposure to GDF-5 as a A. Friedmann1;
K. Stapelfeldt1; PLGA-fiber reinforced, M. Tortorici (Sp)1; M. Gebinoga1; A. Schober1 basis for its therapeutic CE.H. Schmelzer1;
P. Mednikova1; brushite-forming cement G.N. Duda1; H. Leemhuis2; 1
Ilmenau University or diagnostic M. Götze3; O. Krimig3;
J. Markhoff1 in a sheep defect model C. Gayer3; S. Checa1; (Germany) application in pre-clinical G. Hillrichs3
1
University of Bremen of lumbar osteopenia A. Petersen1 large animal models 1
Fraunhofer Institute for
(Germany) F. Gunnella (Sp)1; 1
Charité - Universitäts- M. Stoica (Sp)1; Microstructure of Materials
E. Kunisch2; S. Maenz3; medizin Berlin (Germany); F. Gunnella1; J. Bossert2; and Systems IMWS, Halle
B. Illerhaus4; M. Bungartz5; 2
Matricel GmbH, A. Borowski3; R.W. Kinne1 (Saale) (Germany);
O. Brinkmann5; J. Bossert6; Herzogenrath (Germany); 1
University Hospital Jena, 2
Anhalt University for
R.W. Kinne1 3
Fraunhofer Institute for Eisenberg (Germany); Applied Sciences, Köthen
1
University Hospital Jena, Laser Technology ILT, 2
Friedrich Schiller (Germany);
Eisenberg (Germany); Aachen (Germany) University Jena (Germany); 3
Merseburg University of
2
Heidelberg University 3
ImmunoTools GmbH, Jena Applied Sciences
Hospital (Germany); (Germany) (Germany)
3
Aesculap AG, Reutlingen 12:50 Development of Enrichment of a grafting
(Germany); bio-inspired material for bone
4
Bundesanstalt für protein-based materials regeneration and
Materialforschung und as novel anti-corrosive infection prophylaxis
-prüfung (BAM), Berlin coatings and B. Wildemann (Sp)1;
(Germany); transparent adhesives N. Bormann2; E. Beuttel2;
5
Waldkrankenhaus Rudolf G. van Keulen (Sp)1 A.-M. Pobloth2; G.N. Duda2
Elle GmbH, Eisenberg 1
Swansea University 1
University Hospital Jena
(Germany); (United Kingdom)
(Germany);
6
Friedrich Schiller University 2
Charité-Universitätmedizin
Jena (Germany) Berlin (Germany)
13:10 Lunch Break
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