BioMAT 2019 08 - May 2019 Weimar, Germany - Program - Deutsche Gesellschaft für Materialkunde eV
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Program
5th Euro
BioMAT 2019
European Symposium and Exhibition
on Biomaterials and Related Areas
08. - 09. May 2019
Weimar, Germany
https://biomat2019.dgm.de
1
Table of Content Welcome Note
Based on the huge success of the previous four Euro BioMAT Symposia 2011 in Jena and in
2013, 2015 and 2017 in Weimar this international conference will be held every two years
in the Jena-Weimar region.
The symposium Euro BioMAT 2019, 08.-09. May 2019, addresses the growing interest of
science and industry in the different aspects of the creation, characterization, testing and
application of biomaterials and closely related areas. The motivation is not only the recent
scientific progress and new challenges of this exciting, strongly interdisciplinary field of
science and engineering. Materials scientists, physicists, chemists, biologists in industrial
R&D as well as medical professionals are increasingly facing situations, where materials are
confronted with high performance requirements and a challenging biological environment
at the same time.
Much of the growth in the area of biomaterials emerged in the USA and Asia over the last
years, but Europe is gaining ground with a fast and steady growth in this field. The German
Materials Society (DGM) and its panel of experts in biomaterials address these developments
with the Euro BioMAT 2019 in Weimar. Euro BioMAT 2019 will present and discuss the
current state of progress and novel trends in the development, characterization, applica-
tion, testing and modelling of biomaterials in basic science and industry. In addition, this
symposium will bring together experts in closely related areas, such as biomimetics, biomi-
General Information 4
neralization and biopolymers.
The Venue 5
Program Committee 6 The organizers at the DGM feel a need to serve the European biomaterials community
beyond other European and world biomaterials congresses with a compact two-day mee-
Topics 8
ting which brings together fascinating science and inspiring people in a delightful setting
Program Overview 10 in historic Weimar in the very heart of Europe. The program of the Euro BioMAT 2019 will
Program Wednesday 12 comprise several invited plenary lectures as well as oal and poster presentations.
Program Wednesday Oral Poster Session 23
We look forward to see you in Weimar 2019!
List of Posters in the Foyer of the Conference Hall 26
Program Thursday 30
List of Authors and Participants 38
List of Exhibitors & Sponsors 42
DGM Panel of Experts for Biomaterials 44
The Otto Schott Institute of Materials Research
/ Chair of Materials Science 45
Tourist Information & Sightseeing-Tour Weimar 46
Klaus D. Jandt Thomas F. Keller
Chairman Vice Chairman
Friedrich Schiller University Jena, Germany DESY Hamburg, Germany
2 3
General Information The Venue
Date Conference Fees on Thursday 09. May 2019 at Location of the Ramada by Distances from the RAMADA
08.-09. May 2019 Young Researchers up to 09:00 a.m. Wyndham BY WYNDHAM Hotel Weimar
30 years
Conference Chairs DGM members 230 EUR Poster Prize Sponsor: The hotel is only a few kilome- Goethe‘s Home: 06 km
Klaus D. Jandt Non-members 300 EUR ters from Weimar city center. Bauhaus Museum: 10 km
Chairman You can reach Weimar City and City Palace and
Friedrich Schiller University Jena, Expert Researchers 31-45 years its numerous sights in just 10 Marstall (stables): 10 km
Germany DGM members 300 EUR minutes by car and 20 minutes Buchenwald Monument: 16 km
Non-members 360 EUR Abstracts by public transport. Park at the River Ilm: 05 km
Thomas F. Keller All abstracts are on display on Bus number 6 stops just Deutsches Nationaltheater
Vice Chairman Professionals University the conference website and will 20 meters from the hotel. The (German National Theater):07 km
DESY Hamburg, Germany DGM members 500 EUR remain online after the hotel‘s proximity to the A4 mo- Anna Amalia Library: 07 km
Non-members 600 EUR conference. torway is ideal for those arriving Park caves: 06 km
Congress Office by car. Jakobskirche: 08 km
Deutsche Gesellschaft für Industry List of Participants Herderkirche: 7.5 km
Materialkunde e.V. DGM members 650 EUR An updated List of Participants is Directions to the Hotel Belvedere Palace: 06 km
c/o INVENTUM GmbH Non-members 780 EUR availble on the conference Tiefurt Mansion: 10 km
Alexia Ploetz homepage: Arrival to the hotel by car: Erfurt and Jena: 30 km
Marie-Curie-Straße 11-17 Lunch A4 motorway: Take the Weimar
53757 Sankt Augustin, Germany Lunch is included in the confe- exit (junction 49); follow the B85
biomat@dgm.de rence fees and will be served on towards Rudolstadt. Then follow
Wednesday and Thursday in the the Hotelroute Süd (South hotel
Conference Website hotel restaurant. route). At the roundabout in
https://biomat2019.dgm.de Legefeld, take the first exit. The
Coffee Breaks Hotel Weimar is situated on the
Conference Language Coffee and refreshments will be left after approx. 200m.
The official congress served during the official breaks.
language will be English Arrival to the hotel by public
Oral Poster Session transport from the railway
Conference Venue The oral poster session will be station:
RAMADA BY WYNDHAM held on Wednesday Plenty of taxis are available at
Weimar 08. May 2019 starting at 18:40 the railway station. The journey
Kastanienallee 1 in the lecture Room Goethe I. from the station to the hotel
99428 Weimar costs around 20.- Euro. There is
Germany Poster Discussion Evening also the option of taking the city
T +49 (0) 30 610819461 Poster authors will have the bus number 6 towards Legefeld.
F +49 (0) 351 21777499 opportunity to discuss their sub- The transfer takes around 20-25
reservation.dresden@gchhotelg- ject with delegates and answer minutes. Current bus timetables
roup.com questions in front of their poster can be requested when making
https://www.ramada-hotel-wei- after the oral poster session. your reservation.
mar.com/en Snacks and beverages will be
offered.
Internet Access
Internet vouchers for
conference visitors can be
purchased at the hotel reception
There is free internet access for Poster Award
the hotel guests. A prize for the best poster will be
awarded by a jury. The winner
will be announced and awarded
4 5
Program Committee
Aldo R. Kaiyong Cai Gabriela Ciapetti David Eglin Matthias Epple Helder A. Santos Thomas Scheibel Norman Stark Bo Su Wojciech Swiesz-
Boccaccini Chongqing Uni- Rizzoli AO Research Ruhr-University University of Hel- University of Bay- Straub Medical University of kowski
University of versity, China Institute Davos, Duisburg- sinki, Finland reuth, Germany AG, Wangs,Swit- Bristol, UK Warsaw Universi-
Orthopaedic
Erlangen- Switzerland Essen, zerland ty of Technology,
Nürnberg, Institute, Germany Poland
Germany Bologna, Italy
Jack Ferrcane Ehud Gazit Maria-Pau Dirk Grijpma Klaus D. Jandt Annelie-Martina Frank Witte Fergal J. O'Brien
Oregon Health Tel Aviv Ginebra University of Friedrich Schiller Weinberg Charité Berlin, Royal College
& Science Uni- University, Technical Univer- Twente, The University Jena, Medizinische Germany of Surgreons
versity, Portland, Israel sity of Catalonia, Netherlands Germany Universität Graz, Ireland RCSI,
USA Spain Austria Dublin, Ireland
Adrian Keller Thomas F. Keller Petra Kluger Veikko Linko João F. Mano
Paderborn Uni- DESY Reutlingen Uni- Aalto University, University of
versity, Germany Hamburg, versity, Germany Finland Minho,
Germany Braga, Portugal
Giovanni Alvaro Mata Werner E.G. Bradley Nelson Kurosch Rezwan,
Marletta Queen Mary Müller ETH Zürich, University of
University of University of Johannes Switzerland Bremen,
Catania, Italy London, UK Gutenberg Uni- Germany
versity Mainz,
Germany
6 7
Topics KONGRESS
UND
FACHAUSSTELLUNG
FÜR INNOVATIVE WERKSTOFFE,
The following subjects will be discussed: VERFAHREN UND ANWENDUNGEN
A Structure and properties of biomaterials
• A1 Bio-nano materials
• A2 Bioactive materials, bioglass and calciumphosphates
• A3 Biodegradable materials SYMPOSIUM
• A4 Bioinspired materials / biomimetic materials ZUR WERKSTOFFWOCHE
• A5 Biological materials and biomineralization
• A6 Computational biomaterials science
• A7 Hydrogels and biobased & synthethic polymers
• A8 Imaging of biomaterials
B Biological response to biomaterials
BIOMATERIALIEN
•
•
B1 Biofilms & antimicrobial biomaterials
B2 Biocompatibility
DONNERSTAG & FREITAG
• B3 Biointerfaces and microenvironments 19.–20. SEPTEMBER 2019
• B4 Clinical performance and microenvironments
• B5 Multi-functional biomaterials
SYMPOSIUMSORGANISATOREN
C Biomaterials applications
PROF. DR. KLAUS D. JANDT
• C1 Current and future challenges for the MedTech industry
Friedrich-Schiller-Universität Jena
• C2 Dental materials
Leiter Lehrstuhl für Materialwissenschaften
• C3 Drug and gene delivery
• C4 Innovation in fabrication including 3D printing / additive manufacturing /
biofabrication of biomaterials
• C5 Responsive and smart biomaterials PROF. DR.-ING. HABIL. ALDO R. BOCCACCINI
• C6 Tissue engineering / regenerative medicine Friedrich-Alexander-Universität Erlangen-Nürnberg
• C7 Materials for ophthalmology Leiter Lehrstuhl Biomaterialien
D Biopolymer-based biomaterials
• D1 Special Session „Biopolymer-based biomaterials“ PROF. DR. THOMAS SCHEIBEL
Universität Bayreuth
Leiter Lehrstuhl Biomaterialien
PD DR.-ING. THOMAS F. KELLER
Deutsches Elektronen-Synchrotron, Hamburg
Erfahrung . Kompetenz . Wissen
8 WWW.WERKSTOFFWOCHE.DE
Deutsche Gesellschaft für Materialkunde e.V. 9
Program Overview Wednesday Program Overview Thursday
Wednesday Thursday
08:00 Poster Mounting and Registration Room Goethe I
08:00 Plenary Lecture: J. Groll
Room Goethe I
09:00 Opening Address: K.D. Jandt 08:30 Plenary Lecture: L.E. Bertassoni
09:15 Plenary Lecture: L. Adler-Abramovich 09:00 Announcement of the Poster Award Winner
09:45 Plenary Lecture: C. Rieker 09:10 Coffee Break
10:15 Coffee Break Room Goethe III Room Bach Room Schiller
Room Goethe III Room Bach Room Schiller 09:40 A5: Biological materials A2: Bioactive materials, C2: Dental materials
and biomineralization bioglass and calcium-
11:00 A7: Hydrogels and B3: Biointerfaces and C4: Innovation in fabri-
biobased & synthetic microenvironments cation including 3D prin- phosphates
polymers ting / additive manufac-
turing / biofabrication of 11:00 Coffee Break
biomaterials
11:30 A4: Bioinspired materials A2: Bioactive materials, C6: Tissue engineering /
/ biomimetic materials bioglass and calcium- regenerative medicine
13:00 Lunch Break phosphates
14:10 A7: Hydrogels and B3: Biointerfaces and D1: Special Session: 13:10 Lunch Break
biobased & synthetic microenvironments Biopolymer-based
polymers biomaterials Room Goethe I
14:20 Round Table Discussion
15:30 C3: Drug and gene Room Goethe III Room Bach Room Schiller
delivery
15:40 A4: Bioinspired materials A3: Biodegradable C6: Tissue engineering /
/ biomimetic materials materials regenerative medicine
16:30 Coffee Break
Room Goethe I
17:00 C3: Drug and gene B1: Biofilms & antimicro- C8: SFB 1278 Polytarget
delivery bial biomaterials - Polymer Nanoparticles 16:40 Closing Remarks
for Drug Delivery
17:40 A8: Imaging of bioma-
terials
Room Goethe I
18:40 Oral Poster Session
Foyer of the conference hotel
20:00 Poster Discussion Evening
10 11
Program Wednesday 08:00 - 09:45 Program Wednesday 09:45 - 10:15
Wednesday Plenary Lecture
08:00 Poster Mounting and Registration 09:45 Metal-on-metal bearings, where is the scandal?
C. Rieker, Zimmer Biomet EMEA (Switzerland)
Room Goethe I
09:00 Opening Address
K.D. Jandt, Chairman of the conference, Friedrich Schiller University Jena (Germany)
Plenary Lecture Metal-on-metal bearings for total hip arthroplasties have an 80-year long clinical history
Chair K.D. Jandt, Chairman of the conference, Friedrich Schiller University Jena (Germany) with a first implantation done in England in 1938. With a few early exceptions, the alloy
used for these metal-on-metal bearings was always a cobalt-chromium-molybdenum
09:15 Learning from Nature to Form New Organic alloy, which is a very common alloy in modern orthopaedic technology.
Materials for Tissue Regeneration
L. Adler-Abramovich, Tel Aviv University (Israel) Based on the good clinical results seen in the early 80’s with some patients with a
metal-on-metal bearing implanted in the 60’s, a research development was conducted
by Sulzer Medizinaltechnik in Switzerland to better understand the tribology of these be-
arings. Two major improvements were made: (1) development of a wrought high carbon
cobalt-chromium-molybdenum alloy and (2) optimization of the bearing clearance. These
The high demand for scaffolds capable of inducing tissue regeneration using minimally two improvements allow Allo Pro and Protek to re-introduce small diameter metal-on-me-
invasive techniques prompts the need for the development of new biomaterials. Herein, tal bearings in the early 90’s under the tradename Metasul™. As the clinical results of
we investigate the ability of different compositions of short self-assembling peptides and these small diameter metal-on-metal bearings were excellent, they were used as a basis
polysaccharides to form extracellular mimicking scaffolds for tissue regeneration. For this for the development of large diameter metal-on-metal bearings, especially for resurfacing
aim, we used various polysaccharides such as hyaluronic acid, a major component of prostheses. The research conducted in the late 90’s demonstrated that large diameter
the extracellular matrix and alginate, a natural anionic biopolymer derived from brown metal-on-metal bearings have definitively an excellent in-vitro tribological behaviour based
seaweeds.These polysaccharides were incorporated with short peptides and amino acids on partial or full film lubrication. These good in-vitro results lead to the market introducti-
building blocks that can form ordered assemblies such as nanotubes, nanospheres, and on of these large diameter metal-on-metal bearings, not only for resurfacing prostheses,
3D-hydrogels with unique biological and physical properties. However, the control over but also for total hip arthroplasties. These bearings were rapidly “adopted” by ortho-
the physical properties of the structure, including mechanical strength, degradation paedic surgeons for their multiple advantages (stability and range of motion). Their early
profile and injectability has remained challenging. In molecular self-assembly, the physical clinical results were promising, but a small number of patients developed some adverse
properties of the formed assemblies are directed by the inherent characteristics of the biological reactions with these bearings.
composing building blocks. Moreover, molecular co-assembly at varied stoichiometry
substantially increases the structural and functional diversity of the formed assemblies, This plenary talk will analyse the reasons for these adverse biological reactions and investi-
allowing to tailor both their architecture as well as their physical properties. gate the patients’ consequences, the media and legal implications of these large diameter
In line with polymer chemistry paradigms, we applied a supramolecular polymer co-as- metal-on-metal bearings.
sembly methodology to modulate the physical properties of hydrogel scaffolds. Using this
approach, we developed a new peptide-based hydrogel with extraordinary rigidity, deri- 10:15 Coffee Break
ved from a synergism between two different short peptides that were co-assembled. Due
to its high stiffness, this hydrogel may serve as a scaffold for bone regeneration. Also, its
tuneable mechanical properties may affect stem cells differentiation to different lineages
as well. The co-assembly approach together with the incorporation of bone ceramics
further enabled us to design a composite organic-inorganic scaffold with high affinity to
hydroxyapatite, allowing bone tissue regeneration.
This work provides a conceptual framework for the utilization of co-assembly strategies to
push the limits of nanostructures physical properties obtained through self-assembly.
12 13
Program Wednesday 11:00 - 11:40 Program Wednesday 11:40 - 12:20
Room Goethe III Room Bach Room Schiller Room Goethe III Room Bach Room Schiller
A7: Hydrogels and B3: Biointerfaces and C4: Innovation in fabri- A7: Hydrogels and B3: Biointerfaces and C4: Innovation in fabri-
biobased & synthetic microenvironments cation including 3D prin- biobased & synthetic microenvironments cation including 3D prin-
polymers ting / additive manufac- polymers (cont.) ting / additive manufac-
turing / biofabrication of (cont.) turing / biofabrication of
biomaterials biomaterials
(cont.)
Chair K.D. Jandt T.F. Keller A. Dorner-Reisel, Chair K.D. Jandt T.F. Keller N.N.
Friedrich Schiller University Deutsches Elektronen-Syn- Schmalkalden University of Friedrich Schiller University Deutsches Elektronen-
Jena (Germany) chrotron DESY, Hamburg Applied Sciences Jena (Germany) Synchrotron DESY,
(Germany) (Germany) Hamburg (Germany)
11:00 Functional materials for Bone marrow analogs 3D Printing of Porous
applications in the brain for studying stem cell Scaffold Designed for 11:40 Hydrogel-based surfaces In vitro short-time 3D printed PLA for mul-
C. Selhuber-Unkel (Sp)1 niches in health and Biomedical Implant for stem cell process method for the deter- tipurpose applications in
1
Kiel University (Germany)
(cont.) Development engineering mination of long-term chemistry and biology
disease
C. Lee-Thedieck (Sp)1; F. Shalchy (Sp)1; C. Lovell2; M. Gepp (Sp)1; A. Serr2; B. stability of implant M. Schneider (Sp)1;
A. Raic1; D. Kratzer1; A. Bhaskar1 Fischer1; A. Vahtrik2; materials A. Taubert1
S. Zippel1;
1
University of Southamp- J.C. Neubauer1; N. Wegner (Sp)1; 1
University of Potsdam
A. Ludwig-Husemann1 ton (United Kingdom); H. Zimmermann2 R. Scholz1; M. Klein1; (Germany)
1
Leibniz University
2
Lucideon ltd., STOKE-ON-
1
Fraunhofer Project Center M. Knyazeva1; F. Walther1
Hannover (Germany) TRENT (United Kingdom) for Stem Cell Process 1
TU Dortmund University
Engineering, Würzburg (Germany)
11:20 3D Environments for Interfacing of human Biomaterial properties (Germany); 2Fraunhofer
Cells – Adaptable Micro- stem cell derived to protect cells in 3D Institute for Biomedical
channels in Biofunctio- neurons with vertically bioprinting Engineering, Sulzbach
nalized Hydrogels aligned nanowires as E. Courtial (Sp)1; (Germany)
(Sp)1; function of nanowire C.A. Marquette1; E. Petiot1
S. Gutekunst1; S. Huth1; length, diameter and 1
Université Claude Bernard
H.C. Trinh1; F. Rasch1; array pitch Lyon1, Villeurbanne
Y.K. Mishra1; R. Adelung1; J. Harberts (Sp)1; (France)
C. Selhuber-Unkel1 R. Zierold1; C. Fendler1;
1
Kiel University (Germany) J. Teuber1; W. Kim2;
A. Fontcuberta i Morral2;
R.H. Blick1
1
Universität Hamburg
(Germany); 2École Poly-
technique Fedérale de
Lausanne (Switzerland)
14 15
Program Wednesday 12:00 - 14:10 Program Wednesday 14:10 - 15:10
Room Goethe III Room Bach Room Schiller 13:00 Lunch Break
A7: Hydrogels and B3: Biointerfaces and C4: Innovation in fabri-
biobased & synthetic microenvironments cation including 3D prin- Room Goethe III Room Bach Room Schiller
polymers (cont.) ting / additive manufac-
(cont.) turing / biofabrication of A7: Hydrogels and B3: Biointerfaces and D1: Special Session:
biomaterials biobased & synthetic microenvironments Biopolymer-based
(cont.) polymers (cont.) biomaterials
(cont.)
12:00 Microstructure, mecha- Creating standardized 3D printing of bone sub- Chair N.N. N.N. A. Keller
nical and tribological wells on solid biomate- stitute materials based Paderborn University
performance of PVA rials for biocompatibility on capillary suspensions (Germany)
hydrogels for cartilage testing D. Menne (Sp)1;
14:10 Hyaluronan-based Nanostructured Surfa- Hierarchical Assembly of
replacement C. Ißleib (Sp)1; E. Preuße1; N. Willenbacher1
hydrogels as ophthalmic ce-Induced Changes in DNA Filaments with
A. Oliveira (Sp)1; O. Seidi2; S. Kurz1; J. Spohn1 1
Karlsruhe Institute of
drug carriers Protein Adsorption and Designer Elastic
R. Colaço1; A. Serro3 1
Fraunhofer Institute for Technology (KIT) (Germany)
T. Walter (Sp)1; Implications on Platelet Properties
1
Universidade de Lisboa Ceramic Technologies and
M. Schnabelrauch1; Adhesion and Activation W. Pfeifer (Sp)1
(Portugal); 2École supérieu- Systems IKTS, Dresden
R. Wyrwa1; C. Altmann1 I. Firkowska-Boden (Sp)1; 1
University of Duisburg-
re d‘ingénieurs de Paris-Est (Germany) 1
INNOVENT e.V., Jena C. Helbing1; X. Zhang1; Essen (UDE) (Germany)
Créteil (France); 3Instituto
(Germany) K.D. Jandt1
Universitário Egas Moniz, 1
Friedrich Schiller University
Lisboa (Portugal)
Jena (Germany)
12:20 New approaches in Corrosion at modular Properties of light-
14:30 A biocompatible rever- Tuning Protein Orien- DNA-functionalization
designable 3D hydrogel taper junctions in anato- weight fibrous struc-
sible thermal actuator tation for Bioactive of surfaces based on
scaffolds via Polyoxa- mical shoulder prosthe- tures made by a foam
with tunable transition Surfaces recombinant spider silk
zoline sis - a retrieval study forming technique temperature G. Marletta (Sp)1; proteins
T. Wloka (Sp)1; M. Crackau (Sp)1; S. Burke (Sp)1 N. Wilharm (Sp)1; G.M.L. Messina1; M. Humenik (Sp)1;
M. Gottschaldt1; N. Märtens1; T. Halle1; 1
Trinity College Dublin T. Fischer2; W. Knolle1; N. Tuccitto1; G. Li Destri1; T. Scheibel1
T. Wloka1; S. Czich2; C.H. Lohmann1; (Ireland) F. Ott2; A. Beck-Sickinger2; C. Mazzuca2; A. Palleschi2 1
University of Bayreuth
K. Liefeith3 J. Bertrand1
M. Zink2; S. Mayr1 1
University of Catania (Germany)
1
Friedrich Schiller University
1
Otto von Guericke Univer- 1
Leibniz Institute of Surface (Italy); 2University of Roma
Jena (Germany); 2Univer- sity Magdeburg (Germany)
Engineering (IOM), Leipzig Tor Vergata (Italy)
sity of Bayreuth, Heilbad (Germany); 2Leipzig Univer-
Heiligenstadt (Germany); sity (Germany)
3
Institute for Bioprocessing
and Analytical Measure- 14:50 Mechanically stable sul- Two-Photon-Lithogra- Plant-Derived Scaffolds
ment Techniques (iba), fobetainc Hydrogels - A phy and Atomic Layer for Tissue Engineering
Heilbad Heiligenstadt candidate for biomedi- Deposition: A Tailor-Ma- Applications
(Germany) cal application de Route for Artificial 3D B. Garipcan (Sp)1;
R. Ihlenburg (Sp)1; Scaffold-Mediated Neu- M. Toker1; S. Rostami1;
12:40 Trends, challenges, and Tribological behaviour A.F. Thünemann2; ronal Network Studies M. Kesici2; Ö. Gül2;
future advancements in of wet bovine bone with K. Brademann-Jock2; Fendler (Sp)1; Ö. Kocatürk1
ophthalmological mate- respect to a metallic K. Saalwaechter3; R. Zierold1; C. Denker2; 1
Bogazici University,
rials and devices implant: effects of load, A. Taubert1 J. Harberts1; G. Loers3; Istanbul (Turkey);
I. Firkowska-Boden (Sp)1 sliding speed, material 1
University of Potsdam M. Münzenberg2; 2
Bilgi University, Istanbul
1
Friedrich Schiller University and sliding orientation (Germany); 2Bundesanstalt R.H. Blick1 (Turkey)
Jena (Germany) J. Nohava (Sp)1; C. Voutat2; für Materialforschung 1
Universität Hamburg
O. Marzieh2; P. Zysset2 und –prüfung (BAM), (Germany); 2University of
1
Anton Paar TriTec SA, Berlin (Germany); 3Mar- Greifswald (Germany);
Peseux (Switzerland); tin-Luther-University Hal- 3
University Medical Center
2
University of Bern (Swit- le-Wittenberg, Halle(Saale) Hamburg-Eppendorf (UKE)
16 zerland) 17
(Germany) (Germany)
Program Wednesday 15:10 - 15:50 Program Wednesday 15:50 - 17:00
Room Goethe III Room Bach Room Schiller Room Goethe III Room Bach Room Schiller
C3: Drug and gene B3: Biointerfaces and D1: Special Session: C3: Drug and gene B3: Biointerfaces and D1: Special Session:
delivery microenvironments Biopolymer-based delivery microenvironments Biopolymer-based
(cont.) biomaterials (cont.) (cont.) biomaterials
(cont.) (cont.)
Chair B. Garipcan, Bogazici Uni-
versity, Istanbul (Turkey) 15:50 Functionalization of Nanoconfinement
Polymer Fibers for Neu- and Santsetsukon-like
15:10 Adhesive drug deli- Bioactive cellulose
ronal Regeneration Nanocrawling Govern
very systems for bone non-woven materials
I. Wille (Sp)1; N. Schmidt1; Fibrinogen Dynamics
healing based on using natural ingre-
P. Behrens1; J. Schulze2; and Self-Assembly on
polyelectrolyte complex dients
A. Warnecke2 Nanostructured Polyme-
nanoparticles K. Römhild (Sp)1; 1
Leibniz University Hanno- ric Surfaces
M. Müller (Sp)1 B. Kosan1; F. Meister1;
ver (Germany); 2Hannover I. Firkowska-Boden (Sp)1;
1
Leibniz Institute of M. Gericke2; T. Heinze2;
Medical School (MHH) X. Zhang1; M.M.L. Arras2;
Polymer Research Dresden T. Müller3; J. Müller3;
(Germany) M.J. Kastantin3;
(Germany) B. Giese3
C. Helbing1; A. Özogul1;
1
Thuringian Institute of
E. Gnecco1;
Textile and Plastics Rese-
D.K. Schwartz3; K.D. Jandt1
arch Rudolstadt e.V (Ger- 1
Friedrich Schiller Univer-
many); 2Friedrich Schiller
sity Jena (Germany); 2Oak
University Jena (Germany);
Ridge National Laboratory,
3
SYNLAB Analytics & Ser-
Oak Ridge, (United States);
vices Germany GmbH, Jena 3
University of Colorado
(Germany)
Boulder, Boulder, Colorado
15:30 Inorganic nanoparticle TiO2 Nanotube Arrays as Programmable pH-res- (United States)
mediated delivery of platform for long-term ponsive DNA nanocapsu-
16:10 Mitotane Loaded Po- Low-temperature-ste-
siRNA organotypic culture and le for loading, encapsu-
ly(2-oxazoline) Micel- rilization method for
K. Besecke (Sp)1; mechanical characteriz- lation, and displaying of
les: Physico-Chemical thermal sensitive bioma-
P. Behrens1; ation of retina explants cargo
Characterization and terials
P. Dillschneider2; – from imaging to H. Ijäs (Sp)1
Cytotoxicity Studies in D. Voigt (Sp)1; E. Klüver1;
M. Stiesch2; A. Hoffmann2; mechanical response 1
University of Jyväskylä,
2D & 3D in Vitro Models. M. Meyer1
H. Hartwig2 S. Friebe (Sp)1; S. Weigel1; Espoo (Finland)
M. Haider (Sp)1; 1
Forschungsinstitut für
1
Leibniz University Hanno- M. Francke1; M. Zink1;
J. Schreiner2; S. Kendl2; Leder und Kunststoffbah-
ver (Germany); 2Hannover S. Mayr1
M. Kroiss2; R. Luxenhofer1 nen gGmbH (FILK), Freiberg
Medical School (MHH) 1
Leipzig University (Ger- 1
University of Würzburg (Germany)
(Germany) many)
(Germany); 2University
Hospital of Würzburg
(Germany)
16:30 Coffee Break
18 19Program Wednesday 17:00 - 17:40 Program Wednesday 17:40 - 18:00
Room Bach Room Schiller Room Goethe III Room Bach Room Schiller
B1: Biofilms & antimicro- C8: SFB 1278 Polytarget A8: Imaging of bioma- B1: Biofilms & anti- C8: SFB 1278 Polytarget
bial biomaterials - Polymer Nanoparticles terials microbial biomaterials: - Polymer Nanoparticles
for Drug Delivery Biofilms & antimicrobial for Drug Delivery based
biomaterials Biomaterials
Chair I. Firkowska-Boden, C. Helbing
Friedrich Schiller University Friedrich Schiller University (cont.) (cont.)
Jena (Germany) Jena (Germany)
17:00 Electro-chemical Inac- Formulation and charac- N.N. N.N.
tivation of Bacteria on terization of drug-loa- 17:40 Angle-resolved light Adhesion of E. coli on Synthesis and Formulati-
Titanium Implants by ded nanoparticles using scattering as versatile nano-rough titanium on of Functional Polyme-
Boron-doped Diamond conventional and new characterization tool for surfaces – image and ric Nanoparticles based
Coating biodegradable polymers surfaces and biological genetic analyses on Poly(methacrylate)s
S. Rosiwal (Sp)1; B. Shkodra-Pula (Sp)1; cells N. Stefani (Sp)1; P. Klemm (Sp)1;
H. Ghanem1; M. Stiesch2; A. Vollrath1; C. Kretzer1; N. Felde (Sp)1; M. Schürmann2; T. Yildirim1; S. Schubert1;
A. Burkovski1; I. Nischang1; O. Werz1; A.-S. Munser, A. Gärtner; V. Schroeckh3; S. Dietrich3; U.S. Schubert1
M. Schuman1; A. Labitzke1 U. S. Schubert1 S. Schröder1; T. Wolf3; K.D. Jandt2; 1
Friedrich Schiller University
1
Friedrich-Alexander-Uni- 1
Friedrich Schiller University A. Tünnermann1 M.T. Figge3; Jena (Germany)
versität Erlangen-Nürnberg Jena (Germany) 1
Fraunhofer Institute for G. Panagiotou3;
(FAU) (Germany); 2Hanno- Applied Optics and Preci- A.A. Brakhage3
ver Medical School (MHH) sion Engineering IOF, Jena 1
Leibniz Institute for
(Germany) (Germany) Natural Product Research
and Infection Biology e. V.,
17:20 The Antimicrobial Ac- Eliminating the third
Jena (Germany); 2Friedrich
tions of Supported Silver variable: The effect of
Schiller University Jena
Nanoparticles crystallinity of polyester
(Germany); 3Leibniz Insti-
H. Cao (Sp)1 based nanoparticles for
tute for Natural Product
1
Shanghai Institute of Cera- drug delivery, isolated
Research and Infection
mics, Chinese Academy of from the influence of
Biology, Jena (Germany)
Sciences (China) the hydrophilic / hydro-
phobic balance
K. Scheuer (Sp)1;
K.D. Jandt1;
U.S. Schubert1; C. Weber1;
D. Bandelli1; C. Helbing1;
J. Alex1
1
Friedrich Schiller University
Jena (Germany)
20 21Program Wednesday 18:20 - 18:40 Oral Poster Session Wednesday 18:40 - 20:00
Room Goethe III Room Bach Room Schiller Room Goethe I
A8: Imaging of bioma- 18:40 Oral poster session
terials Chair T.F. Keller
(cont.) Deutsches Elektronen-Synchrotron DESY, Hamburg (Germany)
C4-33 Effect of surface processing on roughness, wettability and cytotoxicity of carbon
18:00 3D characterization of Nano-rough titanium Polyesteramide Nano- fiber-reinforced polyetheretherketone (PEEK) composite fabricated by fused
scaffolds for culturing surfaces created by wet particles with “stealth deposition modeling
and tissue engineering alkaline etching and PVD polymer” shell X. Han (Sp)1; C. Yang2; S. Spintzyk1; L. Scheideler1; .D. Li 2; J. Geis-Gerstorfer1; F. Rupp1
A. Cecilia (Sp)1; M. Schürmann (Sp)1; M. Dirauf (Sp)1; 1
University Hospital Tübingen (Germany); 2Xi’an Jiaotong University, Xi‘an (China)
V. Weinhardt2; B. Zhao1; J. Bossert1; I. Muljajew1; C. Weber1; B1-23 Characterisation of bactericidal titanium surfaces using electron microscopy
R. Hofmann1; K.D. Jandt1 U.S. Schubert1 J. Jenkins (Sp)1; S. Kulkarni2; T.F. Keller2; A. Nobbs1; P. Verkade1; B. Su1;
M. Zuber1; F. Gruhl1; 1
Friedrich Schiller University 1
Friedrich Schiller University 1
University of Bristol (United Kingdom); 2Deutsches Elektronen-Synchrotron DESY, Ham-
A. Bäcker1; Jena (Germany) Jena (Germany) burg (Germany)
R. Surmenev³;
M. Surmeneva³; C4-1 Fabrication of Alginate/Honey Scaffolds by 3D bio-printing and studying their
N. Aadepu¹; Mechanical, Morphological and Cell Viability Properties for in-situ Skin Tissue
S. Shkarina³; Engineering Applications
T. Baumbach¹ S. Datta (Sp)1; V. Vyas1; R. Barua1; R. Sarkar1; A. Barui1; A. RoyChowdhury1; P. Datta1
¹Karlsruhe Institute of
1
Indian Institute of Engineering Science and Technology (IIEST), West Bengal (India)
Technology (KIT), Eg- A1-6 Parvovirus B19 virus-like particles as platform for the development of biomateri-
genstein-Leopoldshafen als
(Germany); ²Heidelberg I. Bustos-Jaimes (Sp)1; M. Cayetano-Cruz1; C.E. Segovia-Trinidad1
University (Germany); 1
National Autonomous University of Mexico (Mexico)
³Tomsk Polytechnic Univer-
A1-18 The Influence of Surface Nanopatterns with varying Periodicities on Protein
sity (Russia)
adsorption
Room Schiller Y. Yang (Sp)1; M. Yu1; G. Grundmeier1; A. Keller1
C8: SFB 1278 Polytarget
1
Paderborn University (Germany)
- Polymer Nanoparticles A4-72 Opaque, Translucent and Transparent Flower Petals
for Drug Delivery based T. Arakawa (Sp)1; O. Karthaus1
Biomaterials 1
Chitose Institute of Science and Technology (Japan)
B3-38 Impact of Surface Morphology and Net Charge of Spider Silk based Materials on
18:20 Perspectives for Imaging Hydrodynamic and Light Interactions with Human Blood Components
of Biomaterials utilizing Scattering Study of Car- S. Lentz (Sp)1; A.C.G. Weiss2; H. Herold1; M. Faria2; Q. Besford2; C. Borkner1; C.-S. Ang2;
highly brilliant X-ray boxymethyl Celluloses E.J. Crampin2; E. Müller3; M. Rottmar3; F. Caruso2; T. Scheibel1
sources M. Grube (Sp)1; 1
University of Bayreuth (Germany); 2The University of Melbourne (Australia); 3EMPA Swiss
T.F. Keller (Sp)1 U.S. Schubert1; Federal Laboratories for Materials Science and Technology, St. Gallen (Switzerland)
1
Deutsches Elektro- I. Nischang1
B1-75 Modulation of Bacteria on Titanium Surfaces via Nanotopography and Antimicro-
nen-Synchrotron DESY, 1
Friedrich Schiller University
bial Peptides
Hamburg (Germany) Jena (Germany)
M. Eales (Sp)1; A. Nobbs1; W. Briscoe1; M. Ryadnov2; T.F. Keller3; B. Su1
1
University of Bristol (United Kingdom); 2National Physical Laboratory (NPL), Teddington,
London (United Kingdom); 3Deutsches Elektronen-Synchrotron DESY, Hamburg (Germany)
A3-78 Degradable hybrid polymers for tissue engineering
J. Schwaiger (Sp)1; S. Nique1; H. Wolter1
1
Fraunhofer Institute for Silicate Research ISC, Würzburg (Germany)
22 23Oral Poster Session Wednesday 18:40 - 20:00 Oral Poster Session Wednesday 18:40 - 20:00
Oral poster session (cont.) Oral poster session (cont.)
B1-141 Antibacterial functionalization of plasma-chemical oxidized titanium surfaces C7-153 Diclofenac and moxifloxacin simultaneous delivery from intraocular lenses for
S. Kranz (Sp)1; A. Guellmar1; J. Schmidt2; S. Tonndorf-Martini1; M. Diefenbeck3; endophthalmitis prophylaxis
B. Sigusch1 A. Serro (Sp)1; B. Saramago2; A. Topete1
1
University Hospital Jena (Germany); 2INNOVENT e.V., Jena (Germany); 1
Instituto Universitário Egas Moniz, Lisbon (Portugal); 2Instituto Superior Técnico, Lisbon
3
Schön Klinik Hamburg-Eilbek (Germany) (Portugal)
A7-93 Thermal crosslinking of hydrophilic polymers using polyperoxides A2-161 Optimization of a calcium phosphate based bone cement formulation
S. Borova (Sp)1; R. Luxenhofer1; V. Tokarev2 R. Colaço (Sp)1; M. Reis1; N. Ribeiro2; L. Figueiredo3; A. Pimenta3; A. Serro1
1
University of Würzburg (Germany); 2Lviv Polytechnic National University (Ukraine) 1
Instituto Superior Técnico, Lisbon (Portugal); 2Hospital dos Lusiadas, Lisbon (Portugal);
3
Bioceramed, Lisbon (Portugal)
A4-81 Poly(peptoid)s: Peptidomimetics as potential Biomaterials
C. Schlutt (Sp)1; R. Luxenhofer1 A2-60 Nanostructured bone apatite-like thin films for bone prostheses
1
University of Würzburg (Germany) G. Graziani (Sp)1; M. De Carolis1; M. Bianchi1; E. Sassoni2; M. Berni1; A. Gambardella1;
N. Baldini1
A1-111 A Nanoscaled Hybrid Coating for Neuronal Electrodes: Nanoporous Silica NPs 1
Rizzoli Orthopaedic Institute, Bologna (Italy); 2Università di Bologna (Italy)
Embodied into Nanoporous Platinum
T. Pinkvos (Sp)1; J. Schulze2; V. Hagemann1; H.A. Schulze1; D.P. Warwas1; S. Zailskas1; A2-177 Low-dose BMP-2 enhances the bone-forming effects of an injectable, PLGA fi-
A. Schierz1; A. Mohmeyer1; M. Jahns1; K.D. Kreisköther1; H.C. Schwarz1; A. Warnecke2; ber-reinforced, brushite-forming cement in sheep lumbar osteopenia defects
P. Behrens1 F. Gunnella (Sp)1; E. Kunisch1; S. Maenz3; B. Illerhaus3; M. Bungartz5; O. Brinkmann5;
1
Leibniz University Hannover (Germany); 2Hannover Medical School (MHH) (Germany) J. Bossert6; R.W. Kinne1
1
University Hospital Jena, Eisenberg (Germany); 2Universitätsklinikum Jena, Jena (Ger-
C2-116 Drug Delivery from Nanoporous Titania Coatings for Dental Application
many); 3Aesculap AG, Tuttlingen (Germany); 4Bundesanstalt für Materialforschung und
S. Zailskas (Sp)1; P. Abendroth1; M. Stiesch2; P. Behrens1
-prüfung (BAM), Berlin (Germany); 5Waldkrankenhaus Rudolf Elle GmbH, Eisenberg (Ger-
1
Leibniz University Hannover (Germany); 2Hannover Medical School (MHH) (Germany)
many); 6Friedrich-Schiller-Universität Jena, Jena (Germany)
A3-119 Waste to resource: Biopolymer from industrial wastewater
A2-178 The PLGA fiber component of brushite-forming calcium phosphate cement in-
R. Nogueira (Sp)1; P. Tamang1
duces the osteogenic differentiation of human adipose tissue-derived stem cells
1
Leibniz University Hannover (Germany)
F. Gunnella (Sp)1; E. Kunisch2; S. Wagner1; F. Dees3; S. Maenz4; J. Bossert5; K.D. Jandt5;
A1-120 Divide and Comprehend: Separating the Effects of Hydrophobicity / Hydrophili- R.W. Kinne1
city and Crystallinity on the Thermal Properties of Polyester Based Drug Delivery 1
University Hospital Jena, Eisenberg (Germany); 2Universitätsklinikum Jena, Jena (Germa-
Systems ny); 3Alere Technologies GmbH, Jena (Germany); 4Aesculap AG, Tuttlingen (Germany);
K. Scheuer (Sp)1; K.D. Jandt1; U.S. Schubert1; C. Weber1; D. Bandelli1; J. Alex1; 5
Friedrich-Schiller-Universität Jena, Jena (Germany)
C. Helbing1
C6-134 Surface functionalization of nanofibers by plasma processing in Ar/CO2/C2H4
1
Friedrich Schiller University Jena (Germany)
discharge
A2-122 Elastic Polymer-Coated Nano- and Macroporous Bioactive Glass-Composites for E. Permyakova (Sp)1; A. Manakhov1; P. Kiruhancev-Korneev1; N. Gloushankova2;
Bone Regeneration D. Shtansky1
M. Lietzow (Sp)1; K. Besecke1; R. Hinterding1; L. Burmeister2; A. Hoffmann2; 1
National University of Science and Technology MISiS, Moskau (Russia); 2N.N. Blokhin
A. Kampmann2; M. Stiesch2; N. Ehlert1 Russian Cancer Research Centre of RAMS, Moscow (Russia)
1
Leibniz University Hannover (Germany); 2Hannover Medical School (MHH) (Germany)
C6-130 Keratinocytes HaCaT Proliferation on a 3D-Printed Chitosan-Collagen Scaffold
E. Hermida (Sp)1; M. Pérez Recalde1; A. González Wusener1; J. Polenta1; A. Bolgiani2
1
National University of San Martin - UNSAM (Argentina); 2BIOMATTER S.A., Buenos Aires
(Argentina)
A7-133 Alginate/silk fibroin-based hydrogels for vascularized tissue constructs
R. Singh (Sp)1; H. Genc1; T. Distler2; R. Detsch2; B. Dietel1; A.R. Boccaccini2; C. Alexiou1;
I. Cicha1
1
Universitätsklinikum Erlangen (Germany); 2Friedrich-Alexander-Universität Erlangen-Nürn-
berg (FAU) (Germany)
24 25Poster Presentations Poster Presentations
20:00 Poster discussion with snacks and drinks in the foyer of the lecture halls A7-89 Modification of bacterial cellulose to enhance anti-inflammatory wound dressing
poster evening barbecue properties
U. Beekmann (Sp)1; P. Zahel1; B. Karl1; L. Schmölz1; S. Lorkowski1; O. Werz1;
Foyer of the conference hotel D. Fischer1; D. Kralisch1
A1-99 Synthesis, solubility and optical activity of chiral
1
Friedrich Schiller University Jena (Germany)
poly(2,4-disubstituted-2-oxazoline)s A7-147 Absolute Characterization of Synthetic Macromolecules used in Biomaterials
M. Yang (Sp)1 Science Applications
1
University of Würzburg (Germany) M. Grube (Sp)1; U.S. Schubert1; I. Nischang1
A1-156 Cytotoxicity of gold nanorods and nanoribbons in context of biomedical
1
Friedrich Schiller University Jena (Germany)
applications A8-115 Biodegradable thermoplastic materials for bimodal imaging containing the mine-
M. Musielak (Sp)1; J. Patalas2; K. Rucinska2; J. Maksim2; A. Bos-Liedke2; A. Molinski2; ral present in the human body
M. Kozak2 Z. Górecka (Sp)1; E. Choinska1; W. Swieszkowski1
1
Adam Mickiewicz University, Poznan (Poland); 2Adam Mickiewicz University in Poznan, 1
Warsaw University of Technology (Poland)
Poznan (Poland)
A8-175 Three-dimensional nanoscale X-ray computed
A1-157 Preliminary studies of synthesis of gold nanoribbons using selected dicationic tomography for the visualisation of cells grown on fibrous scaffolds
surfactants J. Martins de Souza e Silva (Sp)1; C. Santos de Oliveira2; A. Trompetero González2;
J. Patalas (Sp)1; J. Maksim1; K. Maksim1; M. Musielak1; A. Bos-Liedke1; A. Molinski1; T. Kürbitz3; T. Hedke4; C.E.H Schmelzer4; R. B. Wehrspohn4
Z. Pietralik1; M. Kozak1 1
Martin-Luther-University Halle-Wittenberg (Germany); 2Martin-Luther-Universität Hal-
1
Adam Mickiewicz University in Poznan, (Poland) le-Wittenberg, Halle (Saale) (Germany); ³Anhalt University of Applied Science, Köthen
A1-160 Ideas on improving the comparability of bio-nano data (Germany); 4Fraunhofer Institute for Microstructure of Materials and Systems IMWS, Halle
H. Cao (Sp)1; X. Liu2; K.D. Jandt1 (Saale) (Germany)
1
Friedrich Schiller University Jena (Germany); 2Shanghai Institute of Ceramics, Chinese B1-90 Nano-rough titanium surfaces created by wet alkaline etching and PVD and their
Academy of Sciences (China) influence on bacterial adhesion as well as protein adsorption
A1-179 Investigating Dynamic Biological Processes with High-Speed, High-Resolution M. Schürmann (Sp)1; N. Stefani2; V. Schroeckh2; A.A. Brakhage2; J. Bossert1; K.D. Jandt1
Correlative AFM-Light Microscopy
1
Friedrich Schiller University Jena (Germany); 2Leibniz Institute for Natural Product Research
O. Pabsch (Sp)1; T. Mueller1; H. Haschke1 and Infection Biology, Jena (Germany)
1
Bruker Nano GmbH, Berlin (Germany) B1-101 Effective strategies for the controlling and dealing with transmission pathway of
A2-59 Dual-setting brushite-silica gel cements – Variations of the monomer precursors pathogens in air traffi
and tuning of the setting parameters C. Helbing (Sp)1; T. Dauben1; C. Dewald1; B. Zhao1; J. Bossert1; K.D. Jandt1
I. Holzmeister (Sp)1; J. Groll1; U. Gbureck1
1
Friedrich Schiller University Jena (Germany)
1
University Hospital of Würzburg (Germany) B1-104 Nanostructured high-pressure laminate surfaces to reduce transmission pathways
A2-165 Influence of Cu2+-doping in β-TCP on the hydration kinetics of brushite cement of pathogens in public transportation
investigated by Rietveld analysis and heat flow calorimetry C. Helbing (Sp)1; T. Dauben1; K. Scheuer1; J. Bossert1; K.D. Jandt1
K. Späth (Sp)1; K. Hurle1; F. Goetz-Neunhoeffer1
1
Friedrich Schiller University Jena (Germany)
1
Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) (Germany) B2-36 Cytotoxicity evaluation of biodegradable Zn-4Cu alloy using L929, Saos-2 and
A3-31 Corrosion behaviour of potencially biodegradable ternary alloy Zn-Mg-Ca TAg cell lines
J. Pinc (Sp)1; J. Capek1; J. Kubasek2; E. Jablonská2 P. Li (Sp)1; W. Zhang2; E. Schweizer1; J. Dai1; D. Alexander1; G. Wan2; J. Geis-Gerstor-
1
Czech Academy of Sciences, Prague (Czech Republic); 2University of Chemistry and Tech- fer1; L. Scheideler1
nology Prague (Czech Republic)
1
University Hospital Tübingen (Germany); 2Southwest Jiaotong University, Chengdu (Chi-
na)
A3-32 Biomineralization of Recombinant Spider Silk Films
V. Neubauer (Sp)1; T. Scheibel1 B2-79 Influence of pulsed bias voltage on the tribological and morphological properties
1
University of Bayreuth (Germany) of a-C coatings deposited by an anodic arc method
I. Erdmann (Sp)1; F. Deuerler1; V. Buck2
A3-126 Improvements in PHB production by wild type Cupriavidus necator using diffe- 1
University of Wuppertal (Germany); 2University of Duisburg-Essen (UDE) (Germany)
rent feeding strategies
E. Hermida (Sp)1; O. Yashchuk1; D. Noseda1; D. Nygaard1
1
National University of San Martin - UNSAM (Argentina)
26 27Poster Presentations Poster Presentations
B2-183 Multi scale topography in titanium alloys by electron beam technique: influence C7-158 Diclofenac release from a silicon based hydrogel for contact lenses controlled by
on the tissue adhesion and bacterial contamination a layer-by-layer coating
F. Warchomicka (Sp)1; C. Ramskogler1; S. Ferraris 2; A. Cochis3; L. Rimondini3; A. Serro (Sp)1; D. Silva2; H. Sousa3; H. Gil3; C. Alvarez-Lorenzo4; B. Saramago2
A. Weinberg4; S. Spriano2; C. Sommitsch1 1
Instituto Universitário Egas Moniz, Lisbon (Portugal); 2Instituto Superior Técnico, Lisbon
1
Graz University of Technology (Austria); 2Politecnico di Torino (Italy); 3Università del (Portugal); 3Universidade de Coimbra (Portugal); 4Universidade de Santiago de Compostela
Piemonte Orientale, Novara (Italy); 4Medical University Graz (Austria) (Portugal)
B3-35 Chairside plasma activation of encapsulated implants: how fast is it? D1-16 Durability analysis of the cryopreservation of DNA origami nanostructures
M. Garcia Chame (Sp)1; F. Rupp1; C. Diener2; J. Geis-Gerstorfer1 Y. Xin (Sp)1; C. Kielar1; X. Xu1; S. Zhu1; N.G. Gorin1; G. Grundmeier1; A. Keller1
1
University Hospital Tübingen (Germany); 2Diener electronic GmbH + Co. KG, Ebhausen 1
Paderborn University (Germany)
(Germany) D1-57 Effects of staple age on DNA origami nanostructure assembly and stability
B3-50 Novel QCM-D/microscopy set-up for real-time analysis of bacterial binding onto C. Kielar (Sp)1; X. Xu1; S. Zhu1; N.G. Gorin1; G. Grundmeier1; A. Keller1
biomaterial-coated sensors 1
Paderborn University (Germany)
Z. Xu (Sp)1; T. Reiner2; L. Scheideler1; S. Krajewski1; J. Geis-Gerstorfer1; F. Gehring2;
F. Rupp1
1
University Hospital Tübingen (Germany); 23T analytik, Tuttlingen (Germany)
B3-86 Analytical investigation of the influence of micro- and nanoplastic particles in
crop plants by electron microscopic imaging and spectroscopy
J. Wissler (Sp)1; D. Dierksen1
1
TESCAN GmbH, Dortmund (Germany)
C2-52 Influence of fluoride corrosion attack on the metal-porcelain bond strength of
TiCr20 compared to titanium
C. Schille (Sp)1; J. Geis-Gerstorfer1; T. Sawada2; S. Takemoto2
1
University Hospital Tübingen (Germany); 2Iwate Medical University (Japan)
C3-84 Bacterial nanocellulose loaded with frankincense extract as natural wound dres-
sing to treat local dermal inflammations
B. Karl (Sp)1; Y. Alkhatib1; U. Beekmann1; G. Blume2; D. Kralisch1; O. Werz¹;
S. Lorkowski1; D. Fischer1
1
Friedrich Schiller University Jena (Germany); 2Sopharcos, Steinau an der Straße (Germany)
C4-128 Characterization of 3D printed bioesorbable scaffolds for bone regeneration
E. Hermida (Sp)1; B. Aráoz1; T. Federico1; G. Gueron2; A. González Wusener1;
E. Vazquez2; A.R. Boccaccini3
1
National University of San Martin - UNSAM (Argentina); 2University of Buenos Aires
(Argentina); 3Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) (Germany)
C6-98 Graded functionalization of polydopamine coated fiber mats as potential implant
for tendon-bone-transition
S. Oehmichen (Sp)1; S. Sydow1; A. Becker2; J. Sundermann1; H. Bunjes1; B. Glasmacher1;
H. Menzel1
1
TU Braunschweig (Germany); 2Leibniz University Hannover (Germany)
C6-138 Enhancing the functionalities of bioactive glass-based scaffolds by novel
polymeric coatings
L. Liverani (Sp)1; E. Christodoulou2; G.S. Theodorou2; S. Heid1; D. Patsiaoura2; D. Bikiaris2;
E. Kontonasaki2; A.R. Boccaccini1
1
Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) (Germany); 2Aristotle University
of Thessaloniki (Greece)
28 29Program Thursday 08:00 - 09:00 Program Thursday 09:00 - 10:20
Room Goethe I 09:00 Announcement of the poster award winner
Plenary Lectures K.D. Jandt, Chairman of the conference, Friedrich Schiller University Jena (Germany)
Chair
08:00 Biofabrication – Chances, Challenges and Limits Poster Award Sponsor
J. Groll, University Hospital Wuerzburg (Germany)
09:10 Coffee Break
Room Goethe III Room Bach Room Schiller
A5: Biological materials A2: Bioactive materials, C2: Dental materials
and biomineralization bioglass and calcium-
Biofabrication is a young field of research that aims at the automated generation of
phosphates
hierarchical tissue-like structures from cells and materials through automated procedures
in Bioprinting or Bioassembly. This approach has the potential to overcome a number of Chair O. Karthaus R.W. Kinne N.N.
classical challenges in relating to organization, personalized shape and mechanical integri- Chitose Institute of Science University Hospital Jena,
ty of generated constructs. and Technology (Japan) Eisenberg (Germany
Although this has allowed achieving some remarkable early successes, it has recently
become evident that the lack of variety in materials that can be formulated together 09:40 Human Aorta under Bioactive Glass Aging First Steps in Oral
with cells for Bioprinting, so called Bioinks, is one major drawback for the complete field. Tensile Stress and Its Impact on Sin- Biofilm Formation – The
Mainly, such materials are hydrogels or hydrogel precursor formulations; however, alter- S. Friebe (Sp)1; tering Interplay of Biopolymers
native approaches both regarding materials and printing techniques have recently been J. Haunschild1; C. Etz1; L. Lefebvre (Sp)1; A. Mari2; in Adsorption Processes
developed to extend this shortcoming. This contribution will give an introduction to the S. Mayr1 P.F. Menci2; C. Charbon- on Dental Materials
field, critically review the current status, including examples of our recent work, and also
1
Leipzig University neau1; L. De Nardo2 S. Ehnert (Sp)1
concern some of the current challenges. (Germany) 1
National Research Council 1
TU Kaiserslautern (Ger-
Canada, Boucherville many)
(Canada); 2Politecnico di
08:30 Digital Light Projection Stereolithography Bioprin- Milano (Italy)
ting and Guided Mineralization of Microscale Tissue
10:00 Honeycomb films prepa- Beyond the shape con- Subtractive vs additive
Models to Study Stem Cell Differentiation and Bone
red by the breath figure trol of hydroxyapatite manufacturing in the
Tissue Engineering
technique can be used nanoparticles: on the production of Zirconia
L.E. Bertassoni, Oregon Health and Science University
as templates for inorga- relevance of the relative pieces for dental appli-
(USA)
nic compounds amount of (01-10)_Ca- cations
O. Karthaus (Sp)1 rich and HA(01-10)_P- A. Branco (Sp)1; R. Silva2;
Fabrication of three-dimensional tissues with controlled microarchitectures has been 1
Chitose Institute of Scien- rich surfaces and related M. Polido1;
shown to enhance tissue functionality. Our group has been interested in developing ce and Technology (Japan) impact on water and C. Figueiredo-Pina3;
3D bioprinting, biofabrication and materials chemistry-based technologies to enhance protein adsorption R. Colaço2; A. Serro1
our ability to regenerate tissues with controlled microarchitectures, physical properties P. Ivanchenko (Sp)1; 1
Instituto Universitário Egas
and overall function. In this seminar, we will present novel SLA/DLP-based 3D printing F. Catalano1; P. Ugliengo1; Moniz, Monte da Caparica
methods to fabricate high-throughput screening platforms to probe mechanotransduction M. Iafisco2; G. Martra1; (Portugal); 2Instituto Superi-
and geometry-controlled mechanisms of stem cell differentiation. Further, we will discuss A. Tampieri2 or Técnico, Lisbon (Portu-
recent biomineralization methods that our lab has developed to engineer bone-like tissues 1
University of Turin, Torino gal); 3Instituto Politécnico
with nanoscale precision. This novel method will be discussed in light of its ability to repli- (Italy); 2National Research de Setúbal (Portugal)
cate the native bone vasculature, innervation, composition, and osteoinductive properties, Council (CNR), Faenza
as well as its ability of replicating the process of cancer invasion (metastasis) into bone. (Italy)
30 31Program Thursday 10:20 - 11:30 Program Thursday 11:30 - 12:10
Room Goethe III Room Bach 11:00 Coffee Break
A5: Biological materials A2: Bioactive materials, C2: Dental materials
Room Goethe III Room Bach Room Schiller
and biomineralization bioglass and calcium- (cont.)
(cont.) phosphates A4: Bioinspired ma- A2: Bioactive materials, C6: Tissue engineering /
(cont.) terials / biomimetic bioglass and calcium- regenerative medicine
materials phosphates
10:20 Structural Differences of Multifunctional nano-
(cont.)
Human and Yak Hair and macroporous bioac-
A. Müllner (Sp)1; tive glass-composites for Chair W. E.G. Müller N.N. C. Lee-Thedieck,
H. Peterlik1; bone regeneration Johannes Leibniz University
D. Brandhuber2 N. Ehlert (Sp)1; M. Liet- Gutenberg University Hannover (Germany)
1
University of Vienna zow1; J. Schaeske2; N. Mainz,
(Austria); 2Less Is More Stumpp2; M. Stiesch2; Germany
Cosmetics GmbH, Vienna L. Burmeister2;
(Austria) A. Hoffmann2; 11:30 Understanding bacterial Hydration mechanism 4D Printing Objects: A
S. Gniesmer2; interactions awith nano- of an injectable apatite New Approach Toward
A. Kampmann2 structured surfaces cement modified with Complex Tissue Enginee-
K. Besecke1 M. Ishak (Sp)1; A. Nobbs1; sodium phytate ring
1
Leibniz University Hanno- W. Briscoe1; S. Kulkarni1; K. Hurle (Sp)1; C. Devillard (Sp)1;
ver (Germany); 2Hannover T.F. Keller2 J. Weichhold2; U. Gbureck2; C. Mandon1;
Medical School (MHH) B. Su1 F. Goetz-Neunhoeffer1 C.A. Marquette1
(Germany) 1
University of Bristol 1
Friedrich-Alexander-Uni- 1
3D.FAB, Villeurbanne
(United Kingdom); 2Deut- versität Erlangen-Nürn- (France)
10:40 Effect of calcium
sches Elektronen-Syn- berg (FAU) (Germany);
phosphate reinforce-
chrotron DESY, Hamburg 2
University of Würzburg,
ment on Gelatin-Chi-
(Germany) Wuerzburg (Germany)
tosan for developing a
3D porous composite 11:50 Self-Assembled Plasma Improved mechanical DLC coated CoCrMo
scaffold for bone tissue Protein Hybrid Nano- properties of brushi- femural parts for knee
engineering- a compara- fibers te-forming calcium prostheses and biomi-
tive study C. Helbing (Sp)1; phosphate cements by metic micro-pattering
K. Maji (Sp)1 T. Deckert-Gaudig2; polymer fiber reinforce- with femto-second laser
1
National Institute of G. Wei3; K. Scheuer1; ment technique
Technology (NIT), Rourkela K.D. Jandt1 I. Firkowska-Boden (Sp)1; A. Dorner-Reisel (Sp)1;
(India) 1
Friedrich Schiller University K.D. Jandt1 S. Weißmantel2
Jena (Germany); 2Leibniz 1
Friedrich Schiller University 1
Schmalkalden Univer-
Institute of Photonic Tech- Jena (Germany) sity of Applied Sciences
nology, Jena (Germany); (Germany); 2Laserinstitut
3
University of Bremen Mittweida (Germany)
(Germany)
32 33Program Thursday 12:10 - 12:30 Program Thursday 12:30 - 14:20
Room Goethe III Room Bach Room Schiller Room Goethe III Room Bach Room Schiller
A4: Bioinspired ma- A2: Bioactive materials, C6: Tissue engineering / A4: Bioinspired ma- A2: Bioactive materials, C6: Tissue engineering /
terials / biomimetic bioglass and calcium- regenerative medicine terials / biomimetic bioglass and calcium- regenerative medicine
materials phosphates (cont.) materials phosphates (cont.)
(cont.) (cont.) (cont.) (cont.)
12:10 Fibrinogen + Salt The GDF5 mutant BB-1 Scaffolds with Multisca- 12:30 Blood plasma like ma- Alkaline phosphata- Nanofibersflakes for 3D
= 3D-nanofibrous may be superior to GDF5 le Mechanical Proper- terial for multiphoton se (ALP) activity of tissue engineering
scaffolds: A new self for the enhancement ties for Endochondral polymerization the ATDC-5 cell line A. Heilmann (Sp)1;
assembly method of bone formation Healing of Large Bone L. Zeußel (Sp)1; following exposure to K. Tobias2; N. Michler2;
D. Brüggemann (Sp)1; induced by an injectable, Defects M. Gebinoga1; A. Scho- GDF-5 as a basis for its A. Friedmann1;
K. Stapelfeldt1; PLGA-fiber reinforced, M. Tortorici (Sp)1; ber1 therapeutic or diagnostic CE.H. Schmelzer1;
P. Mednikova1; brushite-forming cement G.N. Duda2; H. Leemhuis3; 1
Ilmenau University application in pre-clinical M. Götze3; O. Krimig3;
J. Markhoff1 in a sheep defect model C. Gayer3; S. Checa2; (Germany) large animal models G. Hillrichs3
1
University of Bremen of lumbar osteopenia A. Petersen2 M. Stoica (Sp)1; 1
Fraunhofer Institute for
(Germany) F. Gunnella (Sp)1; 1
Charité - Universitätsmedi- F. Gunnella1; J. Bossert2; Microstructure of Materials
E. Kunisch2; S. Maenz3; zin Berlin (Germany); 2Cha- A. Borowski3; R.W. Kinne1 and Systems IMWS, Halle
B. Illerhaus3; M. Bungartz5; rité – Universitätsmedizin 1
University Hospital Jena, (Saale) (Germany); 2Anhalt
O. Brinkmann5; J. Bossert6; Berlin (Germany); 3Matricel Eisenberg (Germany); University for Applied
R.W. Kinne1 GmbH, Herzogenrath 2
Friedrich Schiller Uni- Sciences, Köthen (Germa-
1
University Hospital Jena, (Germany); 4Fraunhofer Ins- versity Jena (Germany); ny); 3Merseburg Univer-
Eisenberg (Germany); 2Hei- titute for Laser Technology 3
ImmunoTools GmbH, Jena sity of Applied Sciences
delberg University Hospital ILT, Aachen (Germany) (Germany) (Germany)
(Germany); 3Aesculap AG, 12:50 Physicochemical Pro- Enrichment of a grafting
Reutlingen (Germany); perties of Sharkskin material for bone rege-
4
Bundesanstalt für Materi- Mimicked Polymeric neration and infection
alforschung und -prüfung Membranes prophylaxis
(BAM), Berlin (Germany); S. Rostami (Sp)1; B. Wildemann (Sp)1;
5
Waldkrankenhaus Rudolf B. Garipcan1 N. Bormann2; E. Beuttel2;
Elle GmbH, Eisenberg (Ger- 1
Bogazici University, Istan- A.-M. Pobloth2; G.N. Duda2
many); 6Friedrich Schiller bul (Turkey 1
University Hospital Jena
University Jena (Germany) (Germany); 2Charité-Uni-
versitätmedizin Berlin
(Germany)
13:10 Lunch Break
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