Soluzioni Innovative per la Radioterapia - Highlights ...

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Soluzioni Innovative per la Radioterapia - Highlights ...
Soluzioni Innovative
per la Radioterapia
Soluzioni Innovative per la Radioterapia - Highlights ...
GammaPod™

AlignRT® Advance

   SpaceOAR™

    Zephyr®
Soluzioni Innovative per la Radioterapia - Highlights ...
GammaPod                                                         ™

GammaPod™ è un’unità di radioterapia stereotassica specifica per
il trattamento del tumore della mammella.

La modalità di irraggiamento consiste in 25 archi radianti non co-
planari con collimatori conici focalizzati in un punto (“punto foca-
le”) all’interno della cavità di trattamento (“Pod”) in cui viene posi-
zionata la mammella. I collimatori sono di due dimensioni, 25 mm e
15 mm di diametro all’isocentro, interscambiabili automaticamente
in maniera dinamica.

                                   3
Soluzioni Innovative per la Radioterapia - Highlights ...
Introducing the system designed to revolutionize
               the management of early stage breast cancer

STEREOTACTIC BODY
RADIATION THERAPY
Noninvasive Breast Immobilization & Prone Positioning

                                           4
Soluzioni Innovative per la Radioterapia - Highlights ...
Creating New Possibilities for Breast Cancer Treatment
Born out of the vision to extend the dosimetric benefits
of stereotactic radiotherapy to patients undergoing breast
conserving treatment, GammaPodTM is a new precision tool
with the potential to change the way early stage breast cancer
is managed. The ability to safely and confidently deliver a focal
dose of radiation to a target within the breast is giving clinicians
the opportunity to elevate the role of breast radiotherapy in
managing patients with early-stage disease.

With GammaPod, radiation oncologists have a new solution for
delivering ultra-accelerated courses of adjuvant stereotactic
partial breast irradiation, neoadjuvant treatments at ablative         GammaPod combines a continuously rotating, 25-source irradiation
                                                                       unit with 15 mm, 25 mm collimators and dynamic table motion
dose levels and reducing tumor bed boosts to a single fraction         during treatment to paint the radiation dose to the target.
for WBI patients.

                       NONINVASIVE                                       Immobilization and
                                                                         Stereotactic Localization
                      The GammaPod breast cup system is designed to provide secure immobilization of
                      the affected breast and ensures setup reproducibility of the patient between imaging
                      and treatment. The two-cup design allows air from between the cups to be evacuated
                      using a suction pump to create a vacuum seal. Many cup sizes are available.

  Inner Cup                                                                               Silicone Flange
  Affected breast conforms to the shape                                                   Adheres the breast cup system
  of the lightweight inner cup when air is                                                to the patient’s chest while joining the
  evacuated from between the cups for                                                     inner and outer cups
  vacuum-assisted immobilization
  Outer Cup                                                                               Fiducial Wire
  Rigid construction to minimize breast                                                   Stereotactic localization tool embedded
  motion when the cup is docked to the                                                    in the outer cup used to create a 3D
  imaging and treatment tables                                                            stereotactic coordinate system

                                                           Efficient Clinical Workflow for Same D
                                                                                                   •   Breast cup locks to
                              •   Breast cup adheres to
                                                                                                       imaging couch
                                  chest wall with adhesive
                                                                                                   •   Imager loader lifts,
                              •   Suction pump creates a
                                                                                                       rotates patient from
                                  mild negative pressure,
                                                                                                       standing to prone
                                  minimizing breast motion
                                                                                                       position and transfers
                                  throughout imaging and
        Immobilize                treatment                                      Scan                  patient couch to
                                                                                                       CT table

                                                                 5
Soluzioni Innovative per la Radioterapia - Highlights ...
DOSE DISTRIBUTIONS MATTER
                                                      A highly conformal dose distribution with
                                                      sharp falloff.
                                                      Uniform target coverage.
                                                      Low doses to the whole breast volume.
                                                      Low heart doses, even with minimal spacing
                                                      from the target.
                                                      It’s a difference you can see.
                                  Heart

                                                              40 Gy (8 Gy x 5 fractions)
                                                         Dosimetric Example - Left Sided Case
                                                                      Fraction 1

                                                      PTV: 53.37 cc       Heart        Chest Wall
                                                      Rx: 8 Gy to     V5: 0.6%      Dmax: 64 cGy
                                                      95% of PTV      Dmean: 11 cGy Rib Dmax: 41 cGy
                PTV

d

e Day Imaging, Planning and Treatment

                 •    Single click stereotactic
                      localization                                                 •   Breast cup locks to
                                                                                       treatment couch as
                 •    Clinician contours VOIs,                                         patient stands on
                      enters prescription                                              treatment loader
                 •    TPS develops plan with                                       •   Loader rotates patient
        Plan          optimal travel path of
                      table for delivery                          Treat            •   Treatment delivered

                                                  6
Soluzioni Innovative per la Radioterapia - Highlights ...
Rethinking “Value” in Breast Radiotherapy for
     Providers and Patients
     GammaPod aligns with the goals of today’s

                                                                                                         USMK18GR01-1
     initiatives to transform the healthcare
     system. Consider the impact that the shift to
     GammaPod stereotactic radiotherapy could
     make in meeting the needs for high-quality,
     cost-effective and patient friendly breast
     cancer care. The shift to noninvasive external
     beam treatments with highly conformal dose
     distributions delivered in less time has the
     potential to drive value for all stakeholders.

                                                               OPTIMIZED FOR
                                                               BREAST CANCER

                                                                 NONINVASIVE

                                                                SHORT COURSE

     POTENTIAL BENEFITS
     Quality                                              Comfort
     •   Minimizing dose to the whole breast              •   Noninvasive immobilization and treatment
         volume, heart and lungs
                                                          •   Automated prone positioning
     •   Confidence in targeting accuracy

     Efficiency                                           Convenience
     •   Shortening treatment to between one and
         five fractions                                   •   Fewer visits to the clinic

     •   Improving patient throughput                     •   Once daily treatments

www.xcision.com

                                                      7
Soluzioni Innovative per la Radioterapia - Highlights ...
AlignRT Advance                ®

AlignRT® Advance rappresenta lo stato dell’arte dei sistemi per Surface
Guided Radiation Therapy (SGRT).

Grazie all’utilizzo di 6 telecamere stereoscopiche HD permette di trac-
ciare la posizione del paziente in tempo reale, sia prima che durante il
trattamento, con precisione sub-millimetrica. Il set-up del paziente sarà
notevolmente più rapido con la sicurezza di rispettare il posizionamento
corretto.

                                    8
Soluzioni Innovative per la Radioterapia - Highlights ...
BREATHTAKING SPEED.
FROM THE LEADERS IN SGRT.

A NEW PLATFORM,                                                         A BETTER FIT WITH YOUR WORKFLOW
                                                                        • Frame rates up to 3x faster providing improved real time performance

A NEW PARADIGM                                                          • One-click SSD reporting

                                                                        • Auto-default to preferred setup option (plan or previous reference
AlignRT® Advance transforms the AlignRT user interface and                capture) and view
workflow with a faster, more streamlined and intuitive experience,
whilst enhancing patient safety.
                                                                        STREAMLINED PATIENT PREPARATION
From the leaders in SGRT, AlignRT Advance is the result of              • Auto-alert for new or replanned patients
invaluable feedback received from hundreds of AlignRT users
                                                                        • Auto-patient creation when plan sent from treatment planning system
whilst treating thousands of cancer patients.
                                                                        • Streamlined import of plan to intuitive patient planning structure

                                                                        MORE FLEXIBLE TREATMENT MANAGEMENT
                                                                        • Option to change to any surface while monitoring

                                                                        • Add and edit regions of interest at any time

                                                                        • Improved bolus workflow

                                                                            I promise you won’t ever look back! AlignRT
                                                                              Advance is very quick & easy to use and
                                                                               means treatment times are minimized.
                                                                                Postural Video makes patient setup and
                                                                                 monitoring in real-time much easier.
                                                                                   Kyle Woods, Lead Therapy Radiographer, Genesis Care Cambridge

                                                                    9
Soluzioni Innovative per la Radioterapia - Highlights ...
FREEDOM TO TRY.
FREEDOM TO CHOOSE.
With AlignRT® Advance, new horizons open in the field
of Surface Guided Radiotherapy. Now you have the
option to explore additional functionality before
choosing what to purchase.

POSTURAL VIDEOTM
• Gain clear positional guidance from multiple angles during
  setup and monitoring

• High resolution and fast frame rate to make patient set up
  and correction much faster

3D PHOTOTM DISPLAY
• Make selecting regions for tracking easier, faster and more accurate

• Clearly identify and avoid hair, clothing, and other obstructions

  NOT ENABLED                                                                 ENABLED

                                                                                        ©2019 Vision RT Ltd. All rights reserved.
                                                                                                          1016-0299 Issue 3.0

                                                                         10
BREATHTAKING SPEED.
FROM THE LEADERS IN SGRT.

ALIGNRT® A NEW PLATFORM,
A NEW PARADIGM
                                                            IMPROVED ACCURACY FOR
                                                            ALL TREATMENTS

A BETTER FIT WITH YOUR WORKFLOW
• Dramatic improvement in frame rate, providing              ADVANCED CAMERA
                                                                                                                MEASURED DATA
  real-time performance                                      OPTIMIZATION TEST
• One-click SSD reporting                                    Absolute positioning
                                                                                                                ≤0.5mm / ≤0.5°
                                                             accuracy
• Auto-default to preferred setup option (plan or
  previous reference capture) and view                       Motion monitoring
                                                                                                                ≤0.2mm / ≤0.1°
                                                             accuracy

STREAMLINED PATIENT PREPARATION                              Non-coplanar tracking
                                                                                                                ≤0.3mm / ≤0.2°
                                                             accuracy*
• Auto-alert for new or replanned patients
                                                          * Includes the most challenging, clinically realistic configurations: couch rotations,
                                                            pod occlusions, and deep isocenters.
• Auto-patient creation when plan sent from
  treatment planning system
• Streamlined import of plan to intuitive patient
  planning structure

MORE FLEXIBLE TREATMENT MANAGEMENT
• Option to change to any surface while monitoring
• Add and edit regions of interest at any time
• Improved bolus workflow

                                                                                                                Specifications subject to change.

                                                     11
FREEDOM TO TRY.
FREEDOM TO CHOOSE.

With AlignRT 6, new horizons open in the field of Surface Guided
Radiotherapy. Now you have the option to explore additional functionality
before choosing what to purchase.

3D PHOTO DISPLAY
                                                                            NOT ENABLED
Make selecting regions for tracking easier and faster
Clearly identify and avoid hair, clothing, and other obstructions

POSTURAL ALIGNMENT
                                                                            ENABLED
Gain clear direction for setup to maximize efficiency
Pink guidelines to preserve patient dignity

                                                                                          ©2019 Vision RT Ltd. All rights reserved.
                                                                                                            1016-0299 Issue 1.2

                                                                    12
SpaceOAR                                             ™

Il sistema SpaceOARTM è un dispositivo ideato allo scopo
di allontanare temporaneamente la parete anteriore del
retto dalla prostata durante la Radioterapia per il
carcinoma della prostata.

SpaceOARTM consiste in idrogel derivato da glicole
polietileni-co (PEG) ottenuto in situ: è biocompatibile,
sintetico, idroso-lubile, non tossico e non immunogeno. Lo
spazio prodotto da SpaceOARTM prende forma mediante la
sua iniezione diretta tra prostata e retto.

                            13
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(İFDFLDFOLQLFD                                                                                                                Idrogel

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• KDQQRPDQWHQXWRODSRWHQ]DQHOGHLFDVLULVSHWWRDOQHO                                                for Health and Care Excellence - NICE
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1. Hamstra DA, Mariados N, Sylvester J, et al. Continued benefit to rectal separation for prostate radiation therapy: Final results of a phase III trial. Int J Radiat
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           DA, Mariados N, Sylvester J, et al. Sexual quality of life following prostate intensity modulated radiation therapy (IMRT) with a rectal/prostate
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 spacer:  Secondary analysis of a phase 3 trial. Pract Radiat Oncol. 2018 Jan - Feb;8(1):e7-e15.
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Ze ph yr   ®

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Zephyr®
  Zephyr®Positioning and
  Patient
  Patient Positioning
  Transfer Systems and
  Transfer Systems
  Implementing Image-Guided
  Radiotherapy
  Implementingwith  Zephyr
               Image-Guided
  Radiotherapy with Zephyr

Zephyr®
Patient Positioning and
Transfer Systems

  Zephyr Patient Positioning and Transfer Systems
  The Zephyr systems utilize patented hover technology to allow patient transfer from imaging
  to treatment while maintaining patient positioning. The Zephyr family consists of the
  following:

    ‡ Zephyr High Dose Rate for Image Guided Brachytherapy
        ‡ Zephyr HDR

    ‡ Zephyr External Beam series for Image Guided Radiotherapy
        ‡ Zephyr XL
        ‡ Zephyr HP
        ‡ Zephyr HP PRO

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Zephyr®
Patient Positioning and
Transfer Systems

  The Zephyr systems allow transfers of immobilized patients
  from imaging to treatment couch with ease.
  ‡   Departments can utilize EXISTING CT/MR scanners and
      treatment machines to bring image-guided radiation
      therapy to the market TODAY.
  ‡   Patients can be setup and immobilized prior to treatment in
      a separate staging area, which will maximize machine
      imaging/treatment time to increase patient throughput.

Zephyr®
Patient Positioning and
Transfer Systems                                                              System Components
                     Zephyr Hover Boards                                    Zephyr Stretchers

                                       Zephyr XL
             Zephyr HDR            For external beam          Zephyr MR Conditional            Zephyr Procedural
        For HDR GYN/Prostate        thoracic/pelvic                 Stretcher                      Stretcher

                                                                             Zephyr Blower

               Zephyr HP             Zephyr HP PRO
         For external beam H/N   For external beam H/N
                                                                               Zephyr Blower

                                                         18
Zephyr®
Patient Positioning and                                                              Ͳ KǀĞƌǀŝĞǁ
Transfer Systems                                                    Image-Guided Brachytherapy

   The Zephyr HDR system utilizes patented hover technology to
   allow patient transfer from procedure to imaging to treatment
   while maintaining patient positioning and minimizing the risk of
   needle/applicator displacement. Integrating the Zephyr HDR
   allows the incorporation of highly accurate planning for image-
   guided brachytherapy (IGBT).

   Zephyr HDR Highlights
   ‡   Allows GYN and prostate HDR procedures
   ‡   Side rails for mounting of stirrups and steppers
   ‡   Footrest permits supine positioning
   ‡   Fits small bore CT and MR systems
   ‡   Capable of multi-directional transfers: lateral (side to side)
       and/or longitudinal (head to foot) transfers

   Benefits of the Zephyr HDR Solution
   ‡   Incorporate IGBT Treatment planning
   ‡   Improve accuracy of HDR treatment
   ‡   Reduce staff requirements and injuries
   ‡   Utilize in CT or MR for IGBT
Zephyr®
Patient Positioning and
Transfer Systems                                                    Image-Guided Brachytherapy

                                  Incorporate IGBT Treatment Planning
                                  ‡   Deliver a higher dose to the target volume
                                  ‡   Deliver a reduced dose to the surrounding tissue and organs-at-risk
                                  ‡   Reduce the occurrence of side-effects

  Improve Accuracy of HDR Treatment
  ‡ Minimizes risk of applicator/needle movement during transfer utilizing hover
    technology
  ‡ Stirrups mounted directly to Zephyr side rails enable the patient to remain in
    the same position throughout imaging and treatment reducing procedure
    start to finish time
  ‡ Easily adjust and remove applicators/needles without repositioning patient
    while providing enhanced access to implant area

                                  Reduce Staff Requirements & Injuries
                                  ‡ Meets No-Lift Policy standards
                                  ‡ Virtually effortless lateral and longitudinal movement alleviating undue
                                    burden and physical strain on staff
                                  ‡ Two people can safely and easily transfer a patient between implant
                                    procedure, imaging, and treatment
                                  ‡ Increase patient comfort and safety by hovering rather than lifting

                                                           19
Zephyr®
Patient Positioning and
Transfer Systems                                                                        HDR Accessories

   A wide range of accessory items allow customization of the Zephyr HDR system to meet the unique needs of
   your department.

   Available Accessories Include:

   ‡   Premium adult and pediatric stirrups
   ‡   Arm board with full articulation
   ‡   Universal clamp bracket for mounting
       articulating arm on the Zephyr HDR hover board
                                                                                                  Stirrups
   ‡   Side rails for mounting of additional accessory
       items
   ‡   Extended rails for mounting dual mount
       steppers                                                   Armboard
   ‡   Docking kits available for a variety of image
       tables

Zephyr®
Patient Positioning and                                                                 Universal Clamp Bracket

Transfer Systems                                                   Image-Guided Radiotherapy

   Zephyr External Beam Series allows physicians to implement Image-guided
   radiotherapy and adaptive therapy strategies using their existing external beam
   treatment equipment and imaging equipment to bring IGRT to the market today.
   With the Zephyr series, maximum use of image-based planning data is possible.
   The patient is scanned and treated in the same position, which will minimize the                 Zephyr XL
   risk of translational and/or rotational positional changes during transfer between          for thoracic/pelvic
   imaging and treatment devices.

   Zephyr External Beam Highlights
   ‡   Designed specifically for proton/photon therapy’s unique requirements
   ‡   Utilization of industry standard patient immobilization and positioning devices
       via Varian’s Exact™ Technology
   ‡   Internal design minimizes imaging artifacts, as well as treatment attenuation
                                                                                                   Zephyr HP
   ‡   Hover technology allows for multi-directional transfers: lateral (side to side)         for head and neck
       and/or longitudinal (head to foot) transfers

   Benefits of the Zephyr External Beam Solution
   ‡   Enabling Adaptive Radiotherapy techniques
   ‡   Increase patient throughput without sacrificing treatment accuracy
   ‡   A variety of Zephyr systems are available which are uniquely tailored to meet
       the requirements in the radiation therapy environment
                                                                                                  Zephyr HP PRO
                                                                                            for proton head and neck

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Zephyr®
Patient Positioning and
Transfer Systems                                                 Image-Guided Radiotherapy

                        Enable adaptive radiotherapy techniques
                        ‡ Incorporating MR imaging enhances visibility of soft tissue differentiation and
                          improves identification of structures
                        ‡ Lowers rate of acute and late toxicities and organs at risk
                        ‡ Improves tumor coverage with a more efficient dose delivery

   Increase patient throughput without sacrificing treatment accuracy
   ‡ Maximizes machine utilization by removing patient setup time from the
     treatment room
   ‡ Maintains patient immobilization and clinical accuracy throughout the
     patient workflow
   ‡ Increases patient comfort and staff safety utilizing patented hover
     technology

                          A variety of Zephyr systems are available which are uniquely tailored to
                          meet the requirements in the radiation therapy environment
                          ‡ Zephyr XL for general patient transfer/treatment
                          ‡ Zephyr HP for head and neck treatments using industry standard thermoplastics
Zephyr®                   ‡ Zephyr HP PRO for use with Orfit’s HP PRO® thermoplastic photon and proton
                            solution
Patient Positioning and
Transfer Systems                                                        External Beam Accessorie

   A wide range of accessory items allow customization of external beam Zephyr systems to meet the unique
   needs of your department.

    Available Accessories Include:

    ‡   Docking kits compatible with industry standard
        indexing solutions
    ‡   MRI coil torso supports
    ‡   MRI coil support for head and neck imaging
    ‡   MRI flat table tops for major OEM MRI systems
                                                                                      MR Head Coil Supports

                             Docking Kits
                                                                                      MR Torso Coil Supports

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Zephyr®
Patient Positioning and
Transfer Systems                                                                           Stretchers

  Benefits of the Zephyr Procedural Stretcher
  ‡    Continuous flat surface with translating top enables smooth
       patient transfer from imaging/treatment to stretcher
  ‡    Safety stops at head/foot stretcher surface
  ‡    Customizable end stops are available
  ‡    Brake and steer activated foot pedals with true direction steering

  Benefits of the Zephyr MR Conditional Stretcher
                                                                              Procedural Stretcher
  ‡    MR conditional up to 3T
  ‡    Continuous flat surface with folding bridge enables smooth
       patient transfer from imaging/treatment to stretcher
  ‡    Four-wheel braking system

Zephyr®
Patient Positioning and                                                     MR Conditional Stretcher

Transfer Systems                                                               Blowers and Hose

   The Zephyr Blowers and Hoses are designed
   specifically for the Zephyr Patient Positioning and
   Transfer Systems, allowing ease of movement by
   providing air flow to the hover board.

   Zephyr Blower
   ‡   Provides low pressure, high volume air flow to the
       hover boards
   ‡   Blower harnesses designed for various                                     Wall Mount
       configurations such as wall mount or stretcher
       mount

   Zephyr Blower Hose
   ‡   Integrated on/off button provides easy access for
       controlling airflow
   ‡   Quick release design
   ‡   Varying lengths available

                                                   Blower Hose                      Stretcher Mount

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Zephyr®
Patient Positioning and
Transfer Systems                         Zephyr Systems

     Zephyr HDR                          Zephyr XL

             Zephyr HP PRO        Zephyr HP

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