ECR TODAY THURSDAY, FEBRUARY 28 - European Society of Radiology

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ECR TODAY THURSDAY, FEBRUARY 28 - European Society of Radiology
THURSDAY, FEBRUARY 28

ECR TODAY
ECR TODAY THURSDAY, FEBRUARY 28 - European Society of Radiology
WOMEN IN FOCUS – THE BIGGER PICTURE

                WF 1 – LEADING BY EXAMPLE
         Thursday, February 28, 12:30–14:00, The Church
                                      CHAIRPERSON
                                H. Hricak; New York, NY/US

                                  SPEAKERS & PANELLISTS
D. Akata; Ankara/TR, L.E. Derchi; Genoa/IT, C. Estrampes; Paris/FR, M.H. Fuchsjäger; Graz/AT,
        H. Hricak; New York, NY/US, L. Leong; Hong Kong/CN, C. Palmer; London/UK

        WF 2 – CHANGING THE IMAGE OF WOMEN
     IN LEADERSHIP: GENERATIONAL DIFFERENCES
                     AND SIMILARITIES
        Thursday, February 28, 15:45–17:00, The Church
                                       MODERATOR
                                R.A. Kubik-Huch; Baden/CH

                                  SPEAKERS & PANELLISTS
U.I. Attenberger; Mannheim/DE, C. Hess; San Francisco, CA/US, R.A. Kubik-Huch; Baden/CH,
          E.A. Morris; New York, NY/US, M.F. Reiser; Munich/DE, V. Vilgrain; Paris/FR

   WF 3 – WOMEN IN CHALLENGING ENVIRONMENTS
          Friday, March 1, 14:00–15:15, The Church
                                       MODERATOR
                              R.G.H. Beets-Tan; Amsterdam/NL

                                 SPEAKERS & PANELLISTS
   Ş. Bahar Özvarış; Ankara/TR, E. Balogun; Lagos/NG, R.G.H. Beets-Tan; Amsterdam/NL,
      D. Husseiny Salama; Cairo/EG, S.F. Khan; Islamabad/PK, L. O’Riordan; Ipswich/UK

             WF 4 – LEADERSHIP AND MENTORSHIP
              Friday, March 1, 16:00–17:25, The Church
                                       MODERATOR
                                 J.E. Husband; London/UK

                               SPEAKERS & PANELLISTS
   M. Abdel-Wahab; Vienna/AT, C. Beardmore; Guildford/UK, H. Hricak; New York, NY/US,
    J.E. Husband; London/UK, V.P. Jackson; Tucson, AZ/US, G.P. Krestin; Rotterdam/NL,
                             G. McGinty; New York, NY/US

                 All sessions will have dedicated rooms for remote viewing
                and will be streamed live online. More info at myESR.org/wif.
ECR TODAY THURSDAY, FEBRUARY 28 - European Society of Radiology
ECR TODAY 2019                 EUROPEAN CONGRESS OF RADIOLOGY
    DAILY NEWS FROM EUROPE’S LEADING IMAGING MEETING | THURSDAY, FEBRUARY 28, 2019

                    3                                                  9                                                  17                                                  25
            HIGHLIGHTS                                     CLINICAL CORNER                              TECHNOLOGY & RESEARCH                                      COMMUNITY NEWS
     African radiologists call for                        Can you do more to improve                    New MRI scanners and patient-centric                    A success story with new challenges:
    more cooperation with the ESR                          communication of critical                   accessories target productivity and better                   European Radiology, the ESR’s
       in radiation protection                              information to patients?                                clinical outcomes                            flagship journal continues to grow

BY FRANCES RYLANDS-MONK

Knowing your differentials
will unlock migration-related
diagnoses
Migration has created new challenges for clinical radiology, largely due to the number
of imported diseases that it generates.
   This trend necessitates the use of    and crucially to raise awareness of
novel imaging strategies and differ-     them among radiologists and other
ent ways of approaching interpre-        health professionals.
tation. At today’s session, ‘Radiology      “The health issues of immigrants
and migrations’, ECR 2019 delegates      are manifold and in many situa-
will hear about the latest think-        tions they are very challenging to
ing from specialists in the field and    physicians. Awareness of these con-
learn how to tackle migration-re-        ditions is mandatory to ensure good
lated cases.                             clinical practice for these patient
   The total number of asylum seek-      populations that carry a huge bur-
ers in countries across the Euro-        den in chronic, infectious, mental,
pean Union has increased from            and neurological diseases,” Akhan
around 15,000 to almost 1.4 million      said.
annually in the last two decades,           Radiologists need to be aware       This photo shows part of a search-
stated Prof. Okan Akhan, who will        of the types of infectious diseases    and-rescue exercise that simulated
moderate the session. These people       immigrants suffer from, such as        migrants arriving by boat during
are fleeing from violence, torture,      tuberculosis, HIV, viral hepatitis,    a Summer School on Refugee and
persecution, and political or eth-       malaria, schistosomiasis, echinococ-   Migrant Health, held in July 2017
nic oppression, and are unable to        cosis, neurocysticercosis or similar   in Syracuse, Italy. If migrants are
return to their country of origin. In    diseases that reflect epidemiology     in a serious medical condition and
addition, the number of economic         in the country of origin. Addition-    treatment cannot wait until arrival      Every migrant that arrives on board undergoes security screening, has their
migrants seeking a better life has       ally, immigrants may present with      in port, the Italian Coast Guard         identification checked and photo taken, and undergoes initial medical screen-
also increased, he noted.                psychological problems, chronic        launches a medical evacuation            ing by the Italian Relief Corps of the Order of Malta (CISOM). Any potentially
   Whatever the reason for migra-        diseases resulting in polymorbid-      operation by helicopter to immedi-       urgent or infectious cases are reported to representatives of the Maritime,
tion, the health of these individ-       ity, cancer, and neurological dis-     ately transfer them to a medical fa-     Air and border Health Office (USMAF) of the Italian Ministry of Health for
uals is important for their social       eases and acute or chronic malnu-      cility onshore. (Provided by WHO/        treatment isolation or emergency evacuation as required. (Provided by WHO/
inclusion and integration in society,    trition. These conditions may result   Paolo di Pietro)                         Paolo di Pietro)
which in turn has an impact on the       in anaemia, growth disorders, men-
sociopolitical and economic out-         tal and physical development dis-
come for this population, accord-        orders, immunosuppression, neu-        spreading across Europe, mainly          their daily practice, and they must      plications, lower mortality rates,
ing to Akhan, professor of radi-         ropathy, bone disorders and other      due to migration. CE has a preva-        remember that what they think is         shorter hospital stays, and lower
ology and chief of interventional        organ dysfunction, and it is easy to   lence of 1% in rural Turkey, and it is   a simple cyst may in reality be more     recurrence rates, he said.
radiology and abdominal imaging          overlook these aspects during daily    also endemic in southern Europe,         complex and dangerous for the               Dr. Bernadette Abela-Ridder,
at Hacettepe University Hospital         clinical work, he explained.           including the Balkan countries,          patient, Akhan suggested.                team leader on neglected zoonotic
in Ankara, Turkey. Besides gener-           Radiological examination of         southern Italy, France, Spain, and          After ultrasound diagnosis of         diseases and neglected tropical dis-
ating discussion about the reasons       these patients is crucial because      Portugal. Case numbers are also          CE and classification, radiologists      eases (NTDs) in the Department
for migration and its humanitarian       imaging plays an important role in     growing in other parts of Europe         should follow up with MRI and MR         for the Control of NTDs of the
consequences, he hopes speakers          the diagnosis and differential diag-   due to immigration and travel to         cholangiopancreatography (MRCP)          World Health Organization (WHO)
will provide analysis of the impor-      nosis of most of these diseases, but   and from endemic regions. This           when communication between the           in Geneva, Switzerland, will pro-
tance of migration-related diseases      many radiologists in western Euro-     means that diagnostic imaging and        cystic cavity and the biliary system     vide her insight into how migra-
and how to recognise them clini-         pean countries are not familiar        interventional procedures for CE         is suspected. Whenever possible,         tion is impacting incidence and
cally and radiologically.                with them.                             treatment is becoming an impor-          the disease should be treated with       outcomes.
   He added that it was important           For instance, the incidence of      tant topic for western and northern      different percutaneous techniques
to keep discussing the phenome-          cystic echinococcosis (CE), other-     European radiologists, who increas-      which, compared to surgery, are
non of migration-related diseases,       wise known as hydatid cysts, is        ingly will encounter this disease in     associated with fewer major com-         continued on page 3

myESR.org                                                                               #ECR2019
ECR TODAY THURSDAY, FEBRUARY 28 - European Society of Radiology
EUROPEAN DIPLOMA IN RADIOLOGY – QUESTION OF THE DAY

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will raffle amongst the winners a free
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                                                     righ                ill
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                                                        14:00h toda
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                                                          BLOG.MYEBR.ORG
ECR TODAY THURSDAY, FEBRUARY 28 - European Society of Radiology
ECR TODAY | THURSDAY, FEBRUARY 28, 2019                                                                                                                  HIGHLIGHTS                              3

continued from page 1                       Outbreaks of dengue, Leishmani-     because of health problems. Better
                                         asis and schistosomiasis have been     data on disease prevalence and bur-     Professional Challenges Session
   With increasing levels of con-        recorded in low prevalence areas       den in migrant populations remain
                                                                                                                        Thursday, February 28, 08:30–10:00, Studio 2019
flict, civil unrest, poverty, and per-   where intermediate hosts could         key to increased awareness in host
secution, there are an estimated         allow for local transmission. The      countries, and timely access to         PC 5 Radiology and migrations
68.5 million people currently for-       prevalence of Chagas disease (also     appropriate care for migrants, she          »»Chairperson’s introduction
cibly displaced worldwide. Mal-          known as American trypanosomi-         continued.                                    O. Akhan; Ankara/TR
nourished people with poor hous-         asis), strongyloidiasis and schisto-      Providing radiology tips dur-
                                                                                                                            »»Impact of migration on health: WHO perspective
ing and sanitation and restricted        somiasis in migrant populations        ing the session, Dr. Tim Weber, sen-
                                                                                                                              S. Severoni; Copenhagen/DK
access to healthcare results in          ranges from 4.2% to 48.5%, 11% to      ior physician at Heidelberg Univer-
populations at a high risk of dis-       56.1%, and 5.8% to 44% respectively.   sity Hospital in Germany, will shed         »»Importance of migration for neglected tropical diseases: WHO
ease, especially NTDs, stated               Picking up on the issue of hyatid   light on the patterns to look for             perspective
Abela-Ridder.                            cysts, Abela-Ridder noted that cases   and how to evaluate unusual radi-             B. Abela-Ridder; Geneva/CH
   Global migration is changing          of CE and neurocysticercosis have      ological conditions, after combin-          »»Clinical importance of the diseases related to migration
the epidemiology of many of these        also been detected in Europe, with     ing patients’ radiological and epide-         T. Junghanss; Heidelberg/DE
diseases with the emergence and          53% of neurocysticercosis cases        miological features for differential        »»Radiology of the diseases related to migration
re-emergence of NTDs in non- or          attributed to immigrants.              diagnosis.                                    T. Weber; Heidelberg/DE
low-endemic countries. The lack             Systematically screening migrant       Finally, the panel discussion will
of awareness, diagnostics and            populations on arrival to a host       focus not only on raising aware-            »»Panel discussion: How do we raise awareness among health
treatment in host countries poses        country to reduce disease progres-     ness among health professionals               professionals to recognise diseases related to migration? How
a challenge to appropriately diag-       sion and severity should be consid-    but also on how future education              can we adapt migration and migration related diseases into our
nosing and treating affected indi-       ered, but she cautioned that effort    programmes might adopt migra-                 education?
viduals, and to establishing the         was needed to ensure that individ-     tion-related disease imaging into
endemic foci of disease, she said.       uals are not discriminated against     the curriculum.

BY MÉLISANDE ROUGER

African radiologists call for more
cooperation with the ESR in
radiation protection
ESR meets Session                                                               African radiologists will share their knowledge and
Thursday, February 28, 10:30–12:00, RoomB                                       experience of medical imaging practice in their
ESR meets Africa
EM 1 Radiology in Africa: facing challenges and opportunities                   respective countries, today during the ‘ESR meets
Presiding:      L.E. Derchi; Genoa/IT                                           Africa’ session. Examples of cooperation with the
                H.A. Gharbi; Tunis/TN
                                                                                European Society of Radiology will be presented,
    »»Chairperson’s introduction
      L.E. Derchi; Genoa/IT
                                                                                notably in radiation protection, a field where efforts
     H.A. Gharbi; Tunis/TN                                                      between Europe and Africa are starting to pay off.
    »»Structured strategies to combat radiation protection
      challenges in Africa. What can the ESR do?
      D. Husseiny Salama; Cairo/EG                                                 Africa is big, diverse and full of     “Our main challenges are in           and this has led to an increase in
    »»Is imaging underused in Africa? East Africa as an example.                possibilities. Its myriad of coun-      training and the implementation         medical imaging procedures using
      Solutions: what can the ESR do?                                           tries (54), languages, cultures         of national legislation that can        radiation, also in Africa.
      S. Vinayak; Nairobi/KE                                                    and economic scenarios offers           help organise the field, especially       Unlike most of the continent,
                                                                                unmatched potential, but it can         regarding radiation protection,”        Tunisia, Algeria and Morocco have
    »»Interlude 1: Enjoy the difference between African and
                                                                                also complicate the organisation of     said Prof. Hassen Gharbi from           dedicated guidelines on ionis-
      European music
                                                                                radiology.                              Tunis, Tunisia, who will co-chair       ing radiation use. But even there,
      H.A. Gharbi; Tunis/TN
                                                                                   Equipment and workforce tend         the session with ESR President          rules must be implemented to help
    »»How to promote radiation protection in West Africa. Needs and             to vary considerably from one           Lorenzo Derchi from Genoa, Italy.       healthcare professionals prescribe
      expected role of the ESR                                                  country to another. For exam-             Technological advances have           examinations adequately.
      E.H. Niang; Dakar Fann/SN                                                 ple, the radiologists’ ratio ranges     opened new horizons for the appli-
    »»Most important challenges for imaging in North Africa                     from 1 to 80 per million population,    cation of ionising radiation in
      L. Rezgui Marhoul; Tunis/TN                                               depending on the country.               healthcare all around the world         continued on page 4
    »»» Interlude 2: Enjoy the difference between Arabic and
      European music
      H.A. Gharbi; Tunis/TN
    »»The WHO’s programme in Africa: the past, the present and the
      future
      M.D.R. Perez; Geneva/CH
    »»Panel discussion: Radiology in Africa, reality and dreams
      G. Frija; Paris/FR
     L.E. Derchi; Genoa/IT
     H.A. Gharbi; Tunis/TN
     D. Husseiny Salama; Cairo/EG
     S. Vinayak; Nairobi/KE
     E.H. Niang; Dakar Fann/SN
     L. Rezgui Marhoul; Tunis/TN
     M.D.R. Perez; Geneva/CH
     B. Mansouri; Algiers/DZ
     K.M. Naidu; Cape Town/ZA
    »»Conclusion
      L.E. Derchi; Genoa/IT
     H.A. Gharbi; Tunis/TN                                                      Prof. Dina Husseiny Salama and Prof. Hassen Gharbi, together with ESR President Prof. Lorenzo E. Derchi and Prof.
                                                                                Guy Frija, Chair of EuroSafe Imaging, surrounded by delegates at the 5th African Society of Radiology conference in
This session is part of the EuroSafe Imaging campaign.                          January 2019, in Cairo, Egypt.

myESR.org                                                                               #ECR2019
ECR TODAY THURSDAY, FEBRUARY 28 - European Society of Radiology
4    HIGHLIGHTS                                                                                                   ECR TODAY | THURSDAY, FEBRUARY 28, 2019

continued from page 3                      Justification of examinations         ciate Institutional Members from
                                        is another key aspect of radiation       Africa, including Algeria, Egypt,
   “There is a growing need for         protection and the ESR is support-       Ivory Coast, Mauritania, Morocco,
structured strategies and a holistic    ing the use and uptake of imaging        Nigeria, South Africa, Tanzania,
approach towards the full integra-      referral guidelines, especially in       Tunisia and Uganda.
tion of radiation safety and clinical   LMICs. The ESR iGuide web por-              Professionals in the field out-
imaging guidelines in Africa,” said     tal is free to use for ESR radiologist   side of Europe can also become cor-
Prof. Dina Husseiny Salama from         members, and a model with unre-          responding members of the ESR.
Cairo, Egypt.                           stricted access for LMICs is cur-        Corresponding members are enti-
   Prof. Husseiny Salama, who will      rently under development.                tled to a wide range of benefits,
talk about radiation protection            “The ESR iGuide is an excellent       including reduced registration fees
during the session, will highlight      online tool to help clinicians jus-      for ECR 20201, free access to all con-
the role of strategic planning for      tify examinations, and it’s already      tents of the ESR e-learning plat-
more cooperation between the ESR        showing results in Egypt. Coop-          form Education on Demand, the
and African radiology societies.        eration with the ESR works on            option to participate in the Euro-
   “There have been proactive           our side, so why not in the rest of      pean Diploma in Radiology (EDiR)         Prof. Dina Husseiny Salama from          Prof. Hassen Gharbi from Tunis,
actions in Africa to improve the        Africa?” Prof. Husseiny Salama           and all the activities of the Euro-      Cairo, Egypt will highlight the role     Tunisia, will co-chair the ‘ESR meets
situation and enhance the imple-        said.                                    pean School of Radiology (ESOR),         of strategic planning for more           Africa’ session with ESR President
mentation of radiation protection          The process for a stepwise imple-     and many more.                           cooperation between the ESR and          Lorenzo Derchi.
in several countries, however fur-      mentation of the ESR iGuide was             Both memberships are com-             African radiology societies in today’s
ther actions and joint activities       started last year at four centres        pletely free of charge.                  ‘ESR meets Africa’ session.
are needed to enhance the process.      of excellence in Cairo. A recently          A 92% increase in abstracts from
Local initiatives work, but we need     performed audit showed that the          Africa was registered for ECR 2019,      that ‘ESR meets Africa’ will be the         Ultrasound can play a major role
to accelerate things through coop-      number of inappropriate referrals        as a result of inviting Africa to the    right place and moment to get to         in promoting radiation protection,
eration with the ESR. Africa needs      declined significantly, especially       ‘ESR meets’ programme. The num-          know each other better,” he said.        as it provides easy access to sophis-
free, evidence-based tools, which a     in the emergency setting. “So far,       ber of African ESR members also             African radiologists have high        ticated diagnostic methods for the
global player like the ESR can pro-     we’ve had 15% fewer inappropri-          rose from 3% to 5% in just over a        hopes regarding their cooperation        poorest patients. “Two thirds of the
vide,” she said.                        ate referrals, which is quite impor-     year. The benefits of joining the        with Europeans, according to Prof.       global population have no access to
   The ESR launched the EuroSafe        tant for patient radiation protec-       ESR must be made even clearer            Gharbi.                                  medical imaging. Ultrasound must
Imaging campaign three years ago        tion and the financial budget of the     south of the Mediterranean, so              “Medical imaging is advanc-           play an important role in radiation
to promote the safe use of ionis-       radiology department,” Prof. Hus-        that African radiologists can enjoy      ing rapidly in Africa but we want        protection and in tropical diseases,
ing radiation in medicine, and is       seiny Salama said.                       all the support the ESR can offer,       things to develop in the utmost          for example hydatid disease, a sce-
now developing a EuroSafe Imag-            The ESR is also supporting Afri-      according to ESR President Prof.         safety conditions and in respect         nario we are commonly faced with
ing Star assessment scheme for          can radiologists by offering the         Lorenzo Derchi.                          with our guidelines. Africa hopes        in Africa,” Gharbi concluded.
low and middle-income coun-             opportunity for non-European                “We hope this is just the start. It   the ESR can help with radiation
tries (LMICs), to recognise imag-       radiological national societies to       is only a matter of making us visi-      protection, and also to help pro-
ing departments that embody best        become Associate Institutional           ble and making the advantages of         mote, advance and homogenise             1 Provided that ESR 2019 membership is activated and

practice in radiation protection.       Members. The ESR has ten Asso-           ESR membership known. We hope            training,” he said.                       approved by August 31, 2019.

                                                                New Frontier: Predicting Breast
                                                                Cancer through Artificial Intelligence

      Leaders in breast cancer detection will share
      their clinical experience with ProFound AI™
      for digital breast tomosynthesis and clinical
      research on risk assessment.

      Networking. Cocktails. Food.

      When: Friday, March 1st, 18:00 CET
      Where: DO & CO Hotel Vienna

                                                                 Space is limited, advanced RSVP required.
                                                                 Please visit X1, booth AI-17 to register and be
                                                                 entered to win an Apple Watch.

                                                                                         #ECR2019                                                                                              myESR.org
ECR TODAY THURSDAY, FEBRUARY 28 - European Society of Radiology
ECR TODAY | THURSDAY, FEBRUARY 28, 2019                                                                                                                    HIGHLIGHTS                                  5

BY MÉLISANDE ROUGER

A new beginning in cancer imaging
                                                                                                                                                                                            O
                                                                                                                                                                                                NC           IC
                                                                                                                                                                                                     OLO G

has just begun, says Beets-Tan
Professor Regina Beets-Tan is chair of the department of radiology at The Netherlands
Cancer Institute in Amsterdam, full professor of radiology at the University of Maastricht
and adjunct professor of abdominal and oncological radiology at the University of
Southern Denmark. She will present the Wilhelm Conrad Röntgen Honorary Lecture,
entitled ‘Oncologic imaging: a new beginning has just begun’ at ECR 2019.
                                       The world of cancer medicine is          colleagues on a 20-minute journey          ing technology (functional MRI,        acts. As much as we learn from cli-
                                       changing rapidly. Major steps for-       towards their future.                      molecular imaging) together with       nicians, we need to be willing to
                                       ward have been taken. Advanced              ECRT: Your field of research is         endoscopy brings us very far. Yet      teach back. We cannot monopo-
                                       imaging and computing technol-           abdominal and oncologic imaging,           some problems remain unsolved,         lise knowledge. We can invent and
                                       ogy, screening programmes; these         especially MRI of rectal cancer.           like the accurate assessment of        investigate, but after that we need
                                       all will result in the early detection   What are the latest developments           nodal disease. There is still a lot    to share. By sharing our knowl-
                                       of more tumours. Minimally inva-         in rectal cancer medicine?                 of work to do and investment in        edge we gain respect. It is with-
                                       sive treatment, including inter-            Regina Beets-Tan: Colorectal            research investigating the role of     out doubt that imaging technology
                                       ventional therapy, will have an          cancer screening programmes and            modern imaging and computing           and diagnosis remain the main-
                                       increasingly important role. Tar-        modern technology in imaging and           imaging in colorectal cancer man-      stay of radiology. These are skills
                                       geted therapy, which specifically        endoscopy have resulted in the             agement is much needed.                that are truly ours, for which our
                                       hits the cancer genes, and immu-         detection of early and smaller rec-           ECRT: What are the challenges       clinical colleagues really need us
                                       notherapy, which uses the patient’s      tal tumours. Multimodality treat-          facing radiologists today and          and, above all, respect us. I am con-
                                       own immune system to kill can-           ment of advanced rectal cancer that        tomorrow?                              vinced that by combining the tech-
                                       cer cells, will result in prolonged      combines radiotherapy with che-               Regina Beets-Tan: Radiology         nological and digital progress with
Prof. Regina Beets-Tan from Amster-    survival of patients who are in          motherapy, or even with immuno-            surely has challenges lying ahead,     a thorough understanding of the
dam will talk about future aspects     the final stage of metastatic dis-       therapy, has resulted in more com-         but challenges create new oppor-       disease and treatment options, we
of oncologic imaging in today’s        ease. It will be ‘precision medicine’;   plete responses, which brings the          tunities. Imaging technology and       will strengthen our role in the mul-
honorary lecture.                      we do not want to give the wrong         need for surgery in these cases into       computational imaging are used         tidisciplinary team.
                                       treatment to the wrong patient.          question. The focus will be on qual-       not only in our own discipline            There could not be a more excit-
                                       As advocated by Prof René Ber-           ity of life. It is going to be more min-   but also in the clinical specialties   ing time for the oncological radiol-
  She shared a few thoughts with       nards, a respected leader in can-        imal invasive treatment and local          around us. We should not be pro-       ogist, because a new beginning in
us on the future of her specialty in   cer research at the Netherlands          tumour excision rather than rectal         tective. Fear should not dictate our   cancer imaging has just begun.
an interview ahead of the congress.    Cancer Institute: ‘Within 15 years,      amputation. We are going for active
  ECR Today: You have chosen           cancer will become a chronic dis-        surveillance (Watch and Wait) for
quite an iconic and broad topic        ease’. And I believe this is true.       complete responders after treat-
                                                                                                                           Wilhelm Conrad Röntgen Honorary Lecture
for this honorary lecture. What        This transformation will change          ment. It will be paramount to per-
points will you cover exactly?         the way we will practice oncologic       form accurate selection and fol-           Thursday, February 28, 12:15–12:45, Room A
  Regina Beets-Tan: The audience       imaging. This will require us to rec-    low-up of patients, and accurately
                                                                                                                           Oncologic imaging: a new beginning has just begun
will get a glimpse of the future of    reate our discipline. With this lec-     predict who will truly benefit from
cancer care and the role of imaging.   ture, I would like to take my young      organ preservation. Modern imag-           Regina G.H. Beets-Tan; Amsterdam/NL

        Dive into
        interventional
        radiology at the
        Cube 2.0
         Open 8:30-17:30
         February 27 - March 2
         at the DC Tower, ECR City

         For more information visit                                                                                                                                      The Cube is located

         www.myESR.org/cube                                                                                                                                              in the cuboid annex
                                                                                                                                                                             of the DC Tower.

myESR.org                                                                                #ECR2019
ECR TODAY THURSDAY, FEBRUARY 28 - European Society of Radiology
ET2019
EUROPEAN CONFERENCE ON EMBOLOTHERAPY
                                                                           EARLY BIR
                                                                           FEES UNTI
                                                                           MARCH 21
                                                                                     D
                                                                                     L
                                                                                     !

EMBOLOTHERAPY
The latest addition to the CIRSE conference family
focusing exclusively on a key area of interventional radiology:
embolisation in all its applications.

June 26-29 | Valencia | Spain
M A S T E R I N G              E M B O L I S AT I O N

Some highlights from the ET 2019 programme
Special Topic Sessions
Examining the current evidence on new or controversial developments
in embolotherapy.

Technical Focus Sessions
Highlighting the latest trends in specific embolic materials, delivery
systems and advanced guiding modalities.

Case Remedy Sessions
Featuring case discussions including therapy options, technical aspects,
outcome and follow-up.

Morbidity and Mortality Conferences
Looking at the “bad days” as well as the “good days” in the angiosuite.

www.ETconference.org

Cardiovascular and Interventional Radiological Society of Europe   C RSE
ECR TODAY THURSDAY, FEBRUARY 28 - European Society of Radiology
ECR TODAY | THURSDAY, FEBRUARY 28, 2019                                                                                                                  HIGHLIGHTS                                       7

BY VIVIENNE RAPER

3D printing makes steady

                                                                                                                                                                           IN
                                                                                                                                                                             FO              C   PH

                                                                                                                                                                                         S
                                                                                                                                                                                  R M AT I            Y SI C S

transition from laboratory bench
to patient bedside
Three-dimensional printing has spread from craniomaxilliofacial surgery to a wide range
of medical disciplines, and can help demonstrate the value of radiologists in a future with
artificial intelligence and machine learning. That’s the view of Dr. Philipp Brantner, joint
head of the 3D Printing Lab at the University Hospital of Basel, Switzerland.
                                        tines because it lies at the cross-     phantoms to help them find and           the hospital where clinicians from       In general, the benefits of 3D
                                        roads of many disciplines and takes     quantify distortions and artefacts       multiple specialties can discuss       printing still need to be proven
                                        the technological lead within hos-      in CT and PET. However, one of the       ideas and get feedback on projects.    in some specialities, according
                                        pitals. Surgeons need radiologists      biggest challenges to implementing       Because the lab is integrated into     to Brantner. He is running tri-
                                        to advise them on the limits of 3D      a 3D printing lab is securing fund-      the hospital PACS, surgeons can        als to see whether the technology
                                        printing and to choose the correct      ing, he continues.                       easily commission 3D print jobs for    brings quantifiable benefits to sur-
                                        imaging protocols for 3D printing          “We rely on research grants to        work – or for training purposes –      gery – an important step to secur-
                                        because the accuracy of the under-      have staff, we don’t have the hos-       via a centralised form.                ing acceptance and funding. He is
                                        lying image controls the fidelity       pital pay somebody to do the 3D             Yet, despite the benefits, Eley     also looking at whether, for exam-
                                        of the resulting anatomical rep-        printing process, because 3D print-      said some people in the hospi-         ple, a 3D model can reduce the time
                                        resentation, he commented.              ing in our centre is not institu-        tal are still unaware of the 3D lab    taken for orbital fracture surgery.
                                           Advising surgeons on the appli-      tionalised yet,” he explained, add-      and its services. In addition, some    Early results look promising. Print-
                                        cations of 3D printing is part of Dr.   ing that he is trying to establish       clinicians feel it would be faster     ing an orbital mesh before surgery
                                        Francesco Moscato’s work at the         3D printing as part of the clinical      to implement their own cheap           can reduce by 30% the time spent
                                        Medical University of Vienna. Mos-      routine.                                 printer rather than using the cen-     in the operating room.
                                        cato, who is an associate professor        The challenge of ongoing fund-        tralised lab.
                                        at the Center for Medical Physics       ing also affects Dr. Karen Eley, a
                                        and Biomedical Engineering, coop-       clinical lecturer in radiology and
                                        erates with a wide variety of sur-      lead on the project to establish a
                                        geons and specialist radiologists       centralised 3D printing lab located
                                        to apply 3D printing to medical         in the media studio at Addenbro-
                                        problems.                               oke’s Hospital, Cambridge, U.K.
                                           “Usually the clinician comes with       “We were funded entirely by
3D printed models in the media          a very diverse set of wishes and        charitable money, which included
studio at Addenbrooke’s Hospital in     thinks the technology can solve         the initial salary costs of our dedi-
Cambridge. (Provided by Dr. Karen       everything, and we have to spend        cated 3D printing technician. Ongo-
Eley)                                   a couple of meetings to understand      ing salary costs are now having to
                                        what they want and what we can          be supplemented by him taking on
                                        offer,” he explained.                   additional roles in the media stu-
   “We don’t know what the future          Moscato, who is primarily a uni-     dio,” she explained.
will look like, but I think we will     versity researcher, usually deals          At today’s session, Eley will dis-
be faced with a very different way      with difficult cases where a sur-       cuss the benefits of setting up a
of working,” he said. “3D print-        geon has a problem with a specific      centralised 3D printing lab. Avoid-
ing might be a useful extension         procedure or a desire to improve it.    ing the high cost of duplicate equip-
to add value to existing imaging        He has obtained a research grant to     ment and consumables is the big-
                                                                                                                                                                                                            B
techniques.”                            study patients at risk of thrombo-      gest benefit, especially in the U.K.’s   A photo of the main 3D printer used at Addenbrooke’s Hospital. (Provided by
   His talk today will cover estab-     embolic complications by using CT       National Health Service. Another         Dr. Karen Eley)
lished and emerging surgical appli-     scans to create transparent silicon     advantage of a centralised facility
cations of 3D printing. These include   casts that can be used to visualise     is having a dedicated technician
creating a 3D model of a fractured      and study intracardiac flow.            who specialises in 3D printing.          Special Focus Session
bone or kidney to help plan mini-          Among his cases was a patient           “The 3D printing technician is
mally invasive procedures.              with a hard-to-find paravalvu-          the most valuable person in the          Thursday, February 28, 16:00–17:30, Room G
   “3D prints help surgeons get a       lar leak around the mitral valve.       lab,” she said. “If we lost him, the     SF 8f The 3D printing lab from bench to bedside
closer understanding of the ana-        The hole was hard to find and the       service would be lost, because no
tomical situation they’re about to      patient had an unsuccessful pro-        one has any spare capacity to take          »»Chairperson’s introduction
see,” Brantner noted. “In the oper-     cedure to close it. “We printed a       on these additional tasks.”                   F. Kainberger; Vienna/AT
ating theatre they don’t have the       model and it turned out there were         The technician saves radiologists        »»Creating a 3D printing lab in radiology
field of view like radiologists do      three possible holes, the largest of    time doing routine image segmen-              F. Moscato; Vienna/AT
with cross-sectional imaging, so a      which was not a straight hole from      tations, allowing them to focus on          »»Cardiovascular applications of 3D printing
3D representation can give a better     the atrium to ventricle,” Moscato       the more specialist and complex               M. Tam; Southend/UK
roadmap to a tumour, for example.”      said. “The interventional cardiolo-     parts of their job. He also ensures
   The future role of radiology         gists could then plan the procedure     the equipment is maintained to a            »»Supporting the surgeon with 3D printing
might be to expand existing imag-       and finally successfully treat the      high standard and keeps abreast of            P. Brantner; Basle/CH
ing services to include the creation    patient.”                               U.K. regulations.                           »»Challenges of centralised 3D printing
of 3D models, and radiology is per-        He is also helping a colleague          Other benefits include informa-            K.A. Eley; Cambridge/UK
fectly positioned to incorporate        who works in hybrid multimodal-         tion sharing and easy commission-
this technology into clinical rou-      ity imaging, by creating anatomical     ing of services. The lab is a hub in        »»Panel discussion: What are real advantages of 3D printing?

     CLINICAL TRIALS                                                       Watch and listen to the results
                                                                           at the SKY HIGH STAGE

     IN RADIOLOGY
                                                                           Wednesday to Friday
                                                                           10:30 – 12:00

     STRAIGHT FROM THE RESEARCH CENTRE …
     … TO THE WORLD’S MOST INNOVATIVE IMAGING MEETING
                                                                                                                                                     Vienna

myESR.org                                                                                 #ECR2019
ECR TODAY THURSDAY, FEBRUARY 28 - European Society of Radiology
The Artificial
Intelligence
Exhibition (AIX)

Making its grand debut at ECR
2019, the AIX brings the hottest
topic in radiology to the heart of
the technical exhibition.

Meet the innovators applying
machine learning, deep learning
and big data to medical imaging,
and take in illuminating sessions
at the AIX Theatre. You can even
start your own deep learning
adventure thanks to self-paced
training provided by Nvidia’s Deep
Learning Institute in partnership
with the ESR.

Whether you’re exploring AI for
the first time, researching it, or just
want to chat about the future over
a free juice at Algorithms Bar, the
AIX is a must visit at ECR 2019!

   The AIX is located in the X1 hall.
   For more details, and the full
   AIX Theatre programme, visit

   www.myESR.org/ai
ECR TODAY | THURSDAY, FEBRUARY 28, 2019

                                             CLINICAL CORNER                                                                                                                                           9

                                                                                              Is 7 Tesla MRI ready yet to go clinical?                               Discussion centres on imaging’s
          10                                                                       12                                                                  13
                       Fierce debate continues over artificial
                       intelligence’s future impact on radiology                              And how can it make a difference?                                      role in cases of pregnancy-associated
                                                                                                                                                                     breast cancer

BY FRANCES RYLANDS-MONK

Can you do more to improve
communication of critical
information to patients?
The radiological community has done a great deal to quash the idea of ‘the invisible
radiologist’ who has little or no contact with patients, but some uncomfortable truths
remain. Anecdotally at least, some patients perceive radiologist presence to lag well
behind that of other specialists, and many medical universities still don’t incorporate
communication training into their curricula.
   Nobody knows better about the          but during the process, she allowed
importance of effective communi-          what she saw on the screen to show
cation when receiving critical infor-     in her face. She looked deeply wor-
mation than patients themselves.          ried, stopped talking to Justich, and
Austrian-born Caroline Justich            didn’t even come back later to say
was diagnosed with two tumours,           goodbye.
a plexus papilloma and a pituitary           With the increasing focus on
adenoma, in 2004 at the age of 27,        early detection, demand for radi-
and she underwent drastic surgery.        ologists’ communication skills will
She resumed her job in institutional      also grow, she suggested. Therefore,
banking until she started a family        certain techniques that don’t take
in 2009, returning to work after each     too much time will be useful. She
maternity leave.                          pointed to the ‘BATHE’ technique,
   Her back problems began dur-           developed in 1999 by U.S. psychia-       Radiologists helped Caroline Justich find the courage to choose to take the plunge into therapy rather than stand
ing her third pregnancy, and when         trists Dr. Joseph A. Lieberman and       hesitant and fearful on the sidelines. (Provided by Diego Artioli www.escapista.net)
the baby was seven months old in          Dr. Marian Stuart. This psychother-
the summer of 2016, Justich broke         apeutic method involves asking
a lumbar vertebra while water-ski-        about patients’ current situation        with incomprehensible examina-             ogists towards their role as clini-     or image-guided intervention and
ing. Doctors had put the recurrent        (Background), how they feel (Affect),    tion results, or receive a letter, which   cally involved doctors has changed      therapy.
pain and fragility down to repeated       their anxieties (Troubles), and their    they might open at a time when             patients’ expectations – and those        “The shortage of clinicians
pregnancies, but two months later         coping strategies (Handling), while      they can’t contact anyone who              of other specialists, according to      in many countries is leading to
she could no longer move and she          being Empathetic.                        could explain its contents, she rec-       Prof. Christian Loewe, co-chair         even heavier schedules in usual
was diagnosed in the October with            Her own studies in industrial psy-    ommended. Instead, wherever pos-           of the session, along with Prof.        outpatient services, and increas-
breast cancer, which had metasta-         chology in the U.S., and her subse-      sible a radiologist needs to be pres-      Michael Fuchsjäger.                     ingly higher numbers of oncology
sised to the liver, L2 to L4 vertebrae,   quent career in sales and corporate      ent to discuss results and to prepare         Besides the traditional need for     patients asking for direct commu-
lymph nodes, and femur. Further-          finance, as well as her direct expe-     patients positively for further steps,     precise written language, radiolo-      nication with the radiologist right
more, there were two types of can-        rience as a patient, has taught Jus-     and they should give hope, show            gists nowadays should be skilled in     after staging CT. Consequently,
cer present.                              tich that a person can say the same      empathy, and deal with this first          direct communication with other         radiologists need to find the right
   She believes that without positive     thing in many different ways, with       stage of shock.                            clinical colleagues and, even more      empathetic words,” Loewe said.
and clear messages from her radiol-       varying impact.                             Justich advocates establishing          importantly, with patients, said          In his introduction today, he
ogist and other healthcare profes-           “How information is transmitted       one radiologist in each institute to       Loewe, who is head of the Cardi-        aims to remind delegates about
sionals, she would have been far less     plays a major role in a patient’s med-   provide patients with clarity and          ovascular & Interventional Radi-        the need to communicate directly
optimistic and more fearful when          ical pathway. My situation was very      support immediately after results,         ology Department at the Medical         with patients as well as highlight
starting her therapy.                     bad, but I had a smart oncologist. He    though she admits that cost implica-       University of Vienna.                   the possible problems, namely the
   Speaking to delegates at today’s       told me that they were already able      tions needed to be weighed against            Increasingly radiologists are the    potential gap that may arise in
session, Justich, who recently            to completely cure 3% of patients        the increase in patient well-being.        first doctors to inform patients        some cases between what is said by
became a member of the ESR’s              at the same clinical stage as myself,       “In my case, it was my two radi-        about a possibly unfavourable find-     radiologists and what is heard by
Patient Advisory Group (ESR-PAG),         and that in many cases they could        ologists who gave me the hope and          ing, particularly during ultrasound,    patients.
will emphasise that radiologists          transform the cancer into a chronic      certainty that I could make it. In my
need to be mindful of their nonver-       disease with patients living well for    mind I thank them both every day
bal communication.                        five to 15 years. There and then I       for their empathy during my first          Special Focus Session
   “As a patient, you always try to       decided I would be a part of the 3%,”    stage of shock and the way they
read the radiologist’s face, or study     she noted.                               stopped me feeling so powerless,”          Thursday, February 28, 16:00–17:30, Room O
how they talk to colleagues while            She pointed to the flipside of how    she said.                                  SF 8c The art to transmit and to receive: how to communicate
your examination takes place. These       the scenario could have played out.         Justich believes that for trainee       critical information to our patients
nonverbal clues lead to uncertainty          “Imagine if he had told me that       radiologists, education programmes
and misinterpretation that result in      97% of diagnosed patients die within     should focus on communication,                »»Chairpersons’ introduction
distress for the patient. This needs      the first five years? My willpower       and in hospitals, there should be a             M.H. Fuchsjäger; Graz/AT
to stop,” she told ECR Today.             would not have been so strong. I         routine review of communication               »»Chairpersons’ introduction (Part 2)
   She believes that some doc-            might not have started therapy at        techniques every other year. Cru-               C. Loewe; Vienna/AT
tors are overwhelmed by the fate          all but rather spent the remaining       cially, when radiologists deliver crit-       »»How patients feel about communication
of their patients and may react           time with my loved ones,” Justich        ical information, patients shouldn’t            C. Justich; Vienna/AT
strangely because they are trying         said.                                    be sent away or left to deal with it
to protect themselves or simply do           Another problem patients face         alone.                                        »»Fundamentals of physician/patient communication
not know what to say. As a case in        is the delay between diagnostic             No doubt many of Justich’s                   L. Fallowfield; Brighton/UK
point, she revealed how the profes-       findings until finally getting an        comments will resonate with the               »»How can we improve communication with our patients?
sional performing her lumbar CT           appointment with the specialist.         panel at today’s session. The con-              F.J. Gilbert; Cambridge/UK
had been friendly before the exam,        Patients should not be sent home         tinuous transformation of radiol-             »»Panel discussion: How to convey that we care

myESR.org                                                                                   #ECR2019
10    CLINICAL CORNER                                                                                                  ECR TODAY | THURSDAY, FEBRUARY 28, 2019

BY VIVIENNE RAPER

Fierce debate continues over                                                                                                                                                                        AI

artificial intelligence’s future
impact on radiology
Whether artificial intelligence (AI) will replace radiologists or make their jobs easier
continues to be a source of intense discussion, but is the speed of technological
development keeping pace with the hype surrounding AI, and what does the future hold?
Today’s Special Focus session will examine the evidence.
   In late 2016, Geoffrey Hinton was      become more of a comprehensive            differences between general image         supervised learning algorithms            Given these challenges for AI, van
famously quoted as saying it was          collector, integrator and interpreter     recognition and medical imaging.          need to use images from multiple        Ginneken expects radiology to sur-
obvious ‘we should stop training          of information – and not just imag-       Langs pointed out that radiologists       sites. Langs, on the other hand, will   vive at least another 50 years. Long-
radiologists’ because they’ll soon be     ing information,” he told ECR Today.      and machine learning researchers          discuss weakly supervised learning,     term predictions, however, are
replaced by AI. His words spurred         “AI is helpful because this role          must work closely together to over-       which has more images available to      always hard to make, he said. The
fierce debate among radiologists          wouldn’t be possible without it.”         come these problems and create            train an algorithm because it uses      invention of deep learning was a
and academics, which shows no                Another participant at today’s         truly novel approaches.                   imaging data and linked informa-        surprise in his field, and nobody can
sign of disappearing today. That’s        session is Prof. Polina Golland, the         “When an algorithm for general         tion generated during clinical rou-     ever be sure when the next unex-
according to Prof. Bram van Gin-          Henry Ellis Warren (1894) professor       visual recognition is applied to med-     tines to train AI software.             pected breakthrough might be.
neken, a professor from the Depart-       of electrical engineering and com-        ical imaging as it is, it struggles to
ment of Radiology, Radboud Uni-           puter science at the Massachusetts        deliver clinically meaningful results
versity, the Netherlands, who will        Institute of Technology in Cam-           since the dominant variability it
explain the basics of deep and            bridge, U.S.                              faces is just natural variability –
machine learning in today’s session.         “Machine learning will free radi-      everyone’s liver and lung are differ-
   AI promises to automate simple,        ologists from tedious work, so they       ent – and most of the variability isn’t
repetitive tasks. Some work, such as      can do more cerebral tasks,” she said.    linked to disease,” he explained.
screening routine mammograms,             “You could ask the question ‘how             Another challenge is what Stieltjes
won’t need radiologists, unless an        would a PC change how people do           describes as the ‘dirtiness’ of medical
abnormality is found – which hap-         accounting in business?’ Looking          data. Data to feed into an algorithm
pens in 1–2% of cases, noted Van          back, the answer is people stopped        may be of low quality compared to
Ginneken. Thirona, a company he           doing arithmetic by hand or on            other non-medical fields, and are
co-founded in 2014, already has a         a calculator – everything is done         often mixed with free text that needs
product on the market that anal-          automatically by a spreadsheet.”          interpretation. This is an issue that
yses CT scans to check if patients           Although specific tasks can be         hospitals and technological partners
are eligible for certain treatments       done with software, AI has not            can face quite often.
for chronic obstructive pulmonary         delivered on all its early promise,          The technology to develop algo-
disease (COPD).                           according to some observers.              rithms also faces challenges. In his
   “We have hundreds of hospitals            “You can see Google Health, etc.       talk, Stieltjes will discuss his two-
worldwide sending us CT scans,” he        struggling in medicine, whereas           year study to develop an algorithm
explained. “Our customers are pul-        they’ve been successful in other          to classify tumours. The study
monary physicians, and they used          fields,” says Dr. Bram Stieltjes, head    annotated 4,000 lesions for super-
to ask a radiologist to look at certain   of research at University Hospital        vised learning, where an algorithm
things, but now they send the scans       Basel, Switzerland.                       is trained using images where the
to an external company and the               Some technologies, such as deep        lesion is manually labelled.
radiologist is out of the loop.”          learning, haven’t made much pro-             “I think this is one of the largest
   Algorithms might help radiolo-         gress after initial breakthroughs,        studies ever done, but it’s – by far –
gists make predictions about the          says van Ginneken, and hospital           not good enough to do the job, basi-
likely prognosis of a disease or the      IT departments are often slow to          cally,” he commented.
effect of a treatment by exploiting       install the software that is avail-          Even with 4,000 labelled images,
information beyond known mark-            able. He anticipates that in 5–10         the group’s dataset wasn’t big
ers, according to Dr. Georg Langs,        years, radiologists will be able to       enough to train the algorithm. Mean-
an associate professor heading the        buy 10–30 software packages that,         while, unsupervised learning, where
Computational Imaging Research            if he’s optimistic, will replace 10–15%   the algorithm learns about tumours
Lab at the Department of Biomed-          of their most tedious tasks. The          from random images, wasn’t good
ical Imaging and Image-guided             hype around AI is being driven by         enough to carry out tasks as com-         Shown here is an ‘image feature’ assay that identifies clusters in large-
Therapy, Medical University of            companies trying to secure money          plex as staging tumours.                  scale medical imaging data of the lung. The clusters carry very specific
Vienna. The data generated by             from investors, he argues.                   To increase the images available to    clinical properties, suggesting that large-scale data can be mined for
unsupervised learning might then             “They promise fantastic things         train an algorithm, Stieltjes and his     disease phenotypes and corresponding markers. It is an illustration of how
be used to create hypotheses for          and make strong promises, but you         colleagues are currently working to       machine learning can be used to discover new patterns and make them
medical research, or to enable the        can already see they’re not deliver-      include annotation for AI as part of      useful for diagnosis and prognosis. (Provided by Johannes Hofmanninger,
delivery of personalised medicine.        ing,” van Ginneken said.                  the radiological workflow. Another        Computational Imaging Research Lab, Medical University of Vienna)
   “The role of radiologists will            The relatively slow pace of devel-     take-home message from his talk
change and I’ll speculate that they’ll    opment can be attributed to the           will be that projects to develop

                                                                                                                              Special Focus Session

                                                                                                                              Thursday, February 28, 16:00–17:30, Room B
                                                                                                                              SF 8a Artificial intelligence (AI): our future cannot be
                                                                                                                              predicted, but we have to be prepared
                                                                                                                                  »»Chairpersons’ introduction
                                                                                                                                    G. Langs; Vienna/AT
                                                                                                                                  »»Basics of machine learning and deep learning
                                                                                                                                    B. Van Ginneken; Nijmegen/NL
                                                                                                                                  »»AI for lesion detection and characterisation
                                                                                                                                    B. Stieltjes; Basle/CH
                                                                                                                                  »»Machine learning in medical imaging going forward
                                                                                                                                    P. Golland; Cambridge, MA/US
                                                                                                                                  »»Which impact does AI have on medicine?
                                                                                                                                    S.O. Schönberg; Mannheim/DE
                                                                                                                                  »»Panel discussion: What is the future role of a radiologist in the
Examples of medical image analysis results that support interventions and enable clinical research.                                 diagnostic process?
(Provided by Dr. Polina Golland and colleagues)

                                                                                             #ECR2019                                                                                  myESR.org
ECR TODAY | THURSDAY, FEBRUARY 28, 2019                                                                                                            CLINICAL CORNER                                                  11

BY MÉLISANDE ROUGER

Deep learning and radiomics:
                                                                                                                                                                                              PH
                                                                                                                                                                                                   Y SI C S    AI

could future lie in combining
best of both?
In an exciting multidisciplinary session today, a panel of experts will highlight the powerful
potential of deep learning in medical imaging and introduce promising solutions, such as
distributed learning, which uses radiomics.
                                                                                       Maastricht, the Netherlands, who                Collecting millions of images from       with a predetermined signature that
                                                                                       now advises the university spinoff           different countries remains an issue,       needs to be validated in the study.
                                                                                       Oncoradiomics                                since data confidentiality legislation         Software must then receive a CE
                                                                                          “There are not that many quanti-          can affect data sharing. To overcome        mark or FDA approval and must be
                                                                                       tative data in the radiology report.         that challenge, Lambin and his team         integrated into workflow. Very often,
                                                                                       Occasionally you have something              propose to distribute learning from         this means integration within an
                                                                                       on maximum tumour diameter.                  federated databases, i.e. to send the       already chaotic hospital IT system.
                                                                                       Healthcare, in general, is a little late.    learning modules to each hospital           Reimbursement can prove difficult
                                                                                       Machines using AI screen your lug-           database instead of having the hospi-       even when added value has been
                                                                                       gage and perform facial recognition          tal send their data into a centralised      shown. “Using our radiomics signa-
                                                                                       at the airport, but healthcare lags          system.                                     ture, we can reduce the number of
                                                                                       behind the rest of the world,” he said.         “The benefit is that hospitals keep      useless interventions in kidney cysts,
                                                                                          With radiomics, five categories of        their databanks within their systems,       for example, but in some countries
                                                                                       quantitative and measurable infor-           which are protected by firewalls,           hospital managers argue that they
                                                                                       mation can be extracted: intensity;          rather than centralising the multiple       are paid per intervention. Financial
                                                                                       tumour shape; tumour texture; wave-          databases from different countries,”        incentives may go in the wrong direc-
                                                                                       length; and complex semantic fea-            he said.                                    tion,” Lambin said.
                                                                                       tures that can represent friction, such         The researchers already tested the          Today radiomics is in the valley of
                                                                                       as contact between the tumour and            solution in various hospitals around        death, a compelling metaphor that
                                                                                       the bone.                                    the world, with results just as good as     is often used to describe the gap
                                                                                          Radiomics can generate 15,000 to          when data is centralised.                   between scientific validation and
                                                                                       20,000 quantitative image charac-               Implementing a radiomics solu-           application in clinical routine. But
                                                                                       teristics, which may indicate gene           tion into clinical practice is a long and   within five to ten years, every hos-
                                                                                       mutations, and enable the differenti-        winding road. Quality research must         pital will use a radiomics solution
                                                                                       ation of aggressive from non-aggres-         be used and evaluated. A quality score      because extracting information
                                                                                       sive tumours, or whether a tumour            for assessing studies is available on       from an existing image is cheaper
                                                                                       responds to immunotherapy or radi-           the radiomics.world website, which          and more attractive than a genomic
                                                                                       otherapy or not. All these tasks can         makes sure there are enough patients        signature, which requires a tissue
                                                                                       be done without using a single drop          involved and no external validation.        sample to be taken and sent to a
                                                                                       of contrast and one can determine               The TRIPOD classification is             lab, or a biopsy that may not repre-
Image from Radiomics: extracting more information from medical images                  the histological type of the tumour          another resource for assessing the          sent a tumour’s evolution over time,
using advanced feature analysis. Lambin P, Rios-Velazquez E, Leijenaar                 by mining the biological information         quality of the biomarkers that are          Lambin predicted. “All these issues
R, Carvalho S, van Stiphout RG, Granton P, Zegers CM, Gillies R, Boellard              from a CT scan.                              used in a trial. Radiomics signatures       disappear with radiomics, but it
R, Dekker A, Aerts HJ. Eur J Cancer. 2012 Mar;48(4):441-6. doi: 10.1016/j.                DL covers pretty much the same            must meet the TRIPOD level 4 crite-         needs to be rigorously validated
ejca.2011.11.036. Epub 2012 Jan 16.                                                    applications as radiomics – auto-            ria to be deemed worthy. Prospective        and fulfil an unmet clinical need to
                                                                                       mated tumour segmentation, patient           studies are sometimes also required,        pay off,” he concluded.
   Artificial intelligence (AI) will pro-      All these numbers can be collected      classification, etc. – but it uses a radi-
foundly change medicine within              and machines can learn from this           cally different method. While in radi-
the next ten years, and radiologists        information, using DL for a large          omics one selects image character-           EFOMP Workshops (European Federation of
and medical physicists have a role          number of tasks, from image pro-           istics with an already known image           Organisations for Medical Physics)
to play in this process, according to       duction to image reconstruction,           signature, such as heterogeneity, this
Prof. Marco Brambilla from Novara,          dose optimisation, image processing        process is not transparent with DL,          Thursday, February 28, 08:30–10:00, Room G
Italy and Prof. John Damilakis from         and more.                                  which also requires huge horsepower.         EF 1 Big data and the big picture: deep learning in
Iraklion, Greece, both medical physi-          Dose optimisation is paramount to       “We don’t know what the image char-          optimisation of medical imaging (part A)
cists who will co-chair the session at      minimising radiation and maintain-         acteristics are that can differentiate
the ECR.                                    ing the highest possible quality. “At      between a malignant and a benign             Moderator:       J. Damilakis; Iraklion/GR
   Algorithms used in AI are based          the moment this task is done manu-         tumour with DL. DL is a super com-
                                                                                                                                        »»Chairperson’s introduction
and trained on huge amounts                 ally, but AI could help adjust dose for    puter. It is powerful but needs at least
of data to be able to distinguish           every patient according to their size,     10,000 images to work. But it is a black           J. Damilakis; Iraklion/GR
whether a tumour is malignant or            weight, sensitivity and other parame-      box; we do not really know how this              »»Imaging and dose biobanks
benign. This is especially true with        ters,” Damilakis suggested.                works and this is annoying because                 E. Neri; Pisa/IT
deep learning (DL), which uses more            Another area is justification, espe-    doctors like to understand the pro-              »»Statistical methods for analysis of multidimensional imaging data
horsepower than other methods.              cially in examinations that use ion-       cess,” Lambin said.                                K. Van Leemput; Copenhagen/DK
   Whatever the AI solution, data           ising radiation. Justification is cur-        DL demands a lot of data to create
robustness must be checked. This            rently based on information in books,      learning databases and sometimes                 »»The use of radiomics in medical imaging
is, to a large extent, part of the med-     but AI could very well help retrieve       this means using synthetic data. “If               P. Lambin; Maastricht/NL
ical physicists’ duties, Brambilla          information from the literature or         we can have a million data, I would
explained. “When it comes to data,          refine tools that already exist, such as   bet that DL would be better than             Thursday, February 28, 10:30–12:00, Room G
we have the old saying of ‘garbage in,      the ESR iGuide, the clinical decision      traditional radiomics, but we would          EF 2 Big data and the big picture: deep learning in
garbage out’. We medical physicists         support system for European imag-          still have the issue of an uninter-          optimisation of medical imaging (part B)
have to check the consistency of the        ing referral guidelines developed by       pretable algorithm,” he said.
data that is provided. We are respon-       the ESR.                                      Current research combines the             Moderator:       M. Brambilla; Novara/IT
sible for the acceptance of all radiol-        DL could also support research in       best of DL – particularly automated
ogy machines and software,” he said.        medical imaging to develop non-in-         segmentation, which is very useful               »»Chairperson’s introduction
   Radiology departments are cur-           vasive imaging-based biomarkers            in clinical trials – with radiomics, by            M. Brambilla; Novara/IT
rently flooded with information.            for radiomics, a field that involves       enforcing robust image characteris-              »»Computer analysis in chest imaging: from rule-based to
Just for an image acquisition proto-        the extraction and mining of a large       tics on DL. “This looks like a promis-             machine learning to deep learning
col, the medical team has to decide         amount of data and quantitative fea-       ing approach for the future,” he said.             B. Van Ginneken; Nijmegen/NL
how the examination should be per-          tures from medical images.                    Many conditions must be met
                                                                                                                                        »»Deep learning in CT optimisation
formed and determine parameters                Radiomics is a major advance for        for this alliance to work. Data is
                                                                                                                                          M. Kachelrieß; Heidelberg/DE
on tube potential, tube current, time,      healthcare, as the information deliv-      required for both approaches,
etc. These decisions generate a lot of      ered by radiology is still based on        so AI modules would need to                      »»From image quality to care outcome
numbers. “For each examination, we          a qualitative and semi-subjective          be constantly updated, as new                      M. Kortesniemi; Helsinki/FI
can have 100 or more values,” Dami-         assessment, according to Philippe          machines and treatments emerge
lakis said.                                 Lambin, a radiation oncologist from        continuously.                                These sessions are part of the EuroSafe Imaging campaign.

myESR.org                                                                                       #ECR2019
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