Understanding the Updated SCRIPT National E-prescribing Standard

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Understanding the Updated SCRIPT National E-prescribing Standard
Understanding the Updated SCRIPT National E-prescribing Standard

                             Understanding the Updated
                             SCRIPT National E-prescribing
                             Standard
                             Wednesday, September 15, 2021

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                             The handout for today’s presentation can be found at:

                        www.nabp.pharmacy/webinar

2

NABP Webinar – September 15, 2021

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Understanding the Updated SCRIPT National E-prescribing Standard
Understanding the Updated SCRIPT National E-prescribing Standard

                                         UNDERSTANDING THE UPDATED SCRIPT

                                             NATIONAL E-PRESCRIBING STANDARD

                                                                     KEN WHITTEMORE, JR, RPH, MBA
                                                                VP, PROFESSIONAL & REGULATORY AFFAIRS

                                                                      LIVE WEBINAR—SEPTEMBER 15, 2021

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3

    FINANCIAL DISCLOSURE

    Ken Whittemore, Jr, declares that, as an employee of Surescripts, LLC, he has a current affiliation or
    financial relationship with an organization that may have a direct interest in the subject matter of this
    continuing pharmacy education program.

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NABP Webinar – September 15, 2021

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Understanding the Updated SCRIPT National E-prescribing Standard
Understanding the Updated SCRIPT National E-prescribing Standard

                                                                     SCRIPT Standard Background

                          SCRIPT is a standard created to facilitate the electronic
                            transfer of prescription data between pharmacists,
                          prescribers, intermediaries, facilities, and PBM/payers.
               •        First published in 1997 by NCPDP and updated at least annually
               •        Medicare Modernization Act (MMA) of 2003 requires that the Secretary of HHS
                        decide which e‐prescribing standard will be used for Medicare Part D—2006
                        MMA pilots pointed to NCPDP SCRIPT
               •        CMS required the industry to move to a new version of SCRIPT on January 1,
                        2020, which is known as Version 2017071 (the previous version of SCRIPT known
                        as Version 10.6 had been in use since 2013)

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               SCRIPT VERSION 2017071                                                    (1) Incorporated new or
                                                                                            enhanced data
                                                                                            segments, elements,
                        HAS UPDATED                                                         and codes to existing
                                                                                            messages
                E-PRESCRIBING IN TWO
                                                                                         (2) Added new message
                         BASIC WAYS                                                          types that allow the
                                                                                             exchange of
                                                                                             information not
                                                                                             contemplated when
                                                                                             SCRIPT was first
                                                                                             created

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NABP Webinar – September 15, 2021

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Understanding the Updated SCRIPT National E-prescribing Standard
Understanding the Updated SCRIPT National E-prescribing Standard

    WHAT’S CHANGED?

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                                      WHAT CHANGED: SCRIPT 2017071 –
                                      Patient
                                                                                  Topic                                  Brief Description

                                                                                 Allergies                      Patient’s allergies can be sent via eRx
                                   Patient
                                  Attributes
                                                                              Former Name          Patient’s former (e.g., Maiden) name may be included in the eRx

                                                                           International Address   XML schema updated to accommodate international addresses

                                                                            Non‐Humans (Pets)        Species can be indicated on eRx, e.g., Canine, Bovine, Feline

                                                                            Primary Language         Patient’s preferred language can be indicated if non‐English

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NABP Webinar – September 15, 2021

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Understanding the Updated SCRIPT National E-prescribing Standard
Understanding the Updated SCRIPT National E-prescribing Standard

                                 WHAT CHANGED: SCRIPT 2017071 –
                                 Prescriber
                                                                             Topic                                         Brief Description

                                                                                                      Mid‐level practitioner Certificate To Prescribe may be sent in
                                                                     Certificate to Prescribe
                             Prescriber                                                                              applicable states/jurisdictions

                             Attributes                             Prohibit Refill Requests &
                                                                                                   Prescribers may indicate that they do not want Renewal Requests
                                                                                                     and also designate an alternate prescriber for follow‐up (e.g.,
                                                                      Follow‐Up Prescriber
                                                                                                                           Urgent Care, ERs)
                                                                                                       Prescriber’s former (e.g., Maiden) name may be included
                                                                         Former Name
                                                                                                                               in the eRx

                                                                      Prescriber Identifiers           Additional prescriber license numbers may be sent in eRx

                                                                    Practice Location Segment      Prescriber’s Practice location may now be sent (e.g., telemedicine)

                                                                          Veterinarians                       Veterinary prescribers now able to send eRx

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                                 WHAT CHANGED: SCRIPT 2017071 –
                                 Prescription
                                                                                  Topic                                          Brief Description

                                                                          1000‐Character Sig (!)            The Directions field has been expanded to 1,000 characters
                           Prescription
                            Attributes                                                                  Proactive approval documentation for pharmacist administration of
                                                                       Authorization to Administer
                                                                                                                        medications (e.g., immunizations)

                                                                                                         Updated indicator for Brand Medically Necessary that is compliant
                                                                       Brand Medically Necessary
                                                                                                                                with CMS guidelines

                                                                                                       Standardized messages to patients – such as “Needs Appointment” –
                                                                             Codified Notes
                                                                                                                          now sent in codified format

                                                                                                        Up to 25 individual ingredients and quantities now available on eRx
                                                                             Compounds (!)
                                                                                                                                  for compounds

                                                                                Delivery                      Prescribers may indicate patient preference for delivery

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NABP Webinar – September 15, 2021

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Understanding the Updated SCRIPT National E-prescribing Standard
Understanding the Updated SCRIPT National E-prescribing Standard

                                 WHAT CHANGED: SCRIPT 2017071 –
                                 Prescription (cont.)
                                                                                Topic                                        Brief Description

                                                                      Insurance Updates (COO
                                                                                                         Realignment/streamlining of third‐party payer‐related info
                           Prescription                                      Segment)

                            Attributes                                                                  Follow‐up reminders for pending requests may now be sent
                                                                        Electronic Follow‐Up
                                                                                                                              electronically

                                                                                                      Prescribers may indicate multiple prescription vials required for
                                                                         Home & School Use
                                                                                                                           home and school use

                                                                           Substance Use             Patient’s social history for substance use may now be sent via eRx

                                                                              Urgent Rx               Prescribers may request expedited processing for a prescription

                                                                                                       The size of a wound may now be sent to assist pharmacist with
                                                                         Wound Information
                                                                                                                      appropriate package size selection

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                                 WHAT CHANGED: SCRIPT 2017071 –
                                 Prescription (cont.)
                                                                               Topic                                       Brief Description

                                                                                                     Additional information needed for Medicare billing of diabetic
                                                                      Diabetic Testing Supplies
                           Prescription                                                                             testing supplies now sent on eRx

                            Attributes                                       Do Not Fill
                                                                                                     Prescribers may indicate a prescription should not be filled for
                                                                                                    cover prescriptions, drug‐to‐drug interactions, or hold for patient
                                                                                                                                 request.

                                                                         Flavoring Indicator           Prescribers may proactively authorize medication flavoring

                                                                    Office of Pharmacy Affairs ID            Enhanced support for 340B information on eRx

                                                                          Order Grouping              Prescriptions may now be grouped together (such as #1 of 3)

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NABP Webinar – September 15, 2021

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Understanding the Updated SCRIPT National E-prescribing Standard

     RXCHANGE
     • BIDIRECTIONAL COMMUNICATION BETWEEN PHARMACISTS AND PRESCRIBERS
     • NOT NEW, BUT HAS BEEN EXPANDED

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13

     PROCESS STEPS: MAIN USE CASE

                                             1. The pharmacist
                                                  sends an                   2. The Surescripts   3. The prescribing    4. The prescriber
                                             RxChange to the                 Network validates     system returns a      responds either
                                                prescriber to                the message and      verify message to        approving or
                                             request a change                   sends to the      confirm the receipt      denying the
                                                 to a fillable               prescriber system.    of the RxChange           change
                                                prescription.

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NABP Webinar – September 15, 2021

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Understanding the Updated SCRIPT National E-prescribing Standard

     SCRIPT 2017071 EXPANDS THE RXCHANGE USE CASES
                                                                                                             Generic
                                                                                                            Substitution

                                                                                             Generic            Prior
                                                                                            Substitution    Authorization

                                                                             Version 10.6
                                                                                                            Therapeutic

                                                                                                                            Version 2017071
                                                                                                            Interchange
                                                                                                Prior
                                                                                            Authorization
                                                                                                              Drug Use
                                                                                                             Evaluation

                                                                                            Therapeutic        Script
                                                                                            Interchange     Clarification

                                                                                                            Out of Stock

                                                                                                             Prescriber
                                                                                                            Authorization

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15

     CANCELRX
     • PRESCRIBER TO PHARMACIST
     • NOT NEW, BUT USE IS GROWING DUE TO PRESCRIBER INTEREST & CONCERNS
       (SEE “UNDERUSE OF ELECTRONIC HEALTH RECORD FEATURES—THE CASE FOR
       CANCELRX,” JAMA INTERNAL MEDICINE ONLINE, AUGUST 30,2021)

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Understanding the Updated SCRIPT National E-prescribing Standard

     CANCELRX WORKFLOW

                                       CancelRx is sent from prescriber’s system to a pharmacist’s system to:
                                        • Discontinue an active prescription with additional fills remaining, OR
                                        • Cancel a prescription that has not been filled.

                                       CancelRx Response is sent from pharmacist’s system to prescriber’s system
                                       to acknowledge or reject the CancelRx (due to inability to match).

                                                                       CancelRx

                                                             EHR                                    CancelRxResponse   PHARMACY
                                                            SYSTEM                                                      SYSTEM

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17

                                                                            RXCHANGE & CANCELRX
                                                                            ENABLEMENT
                                                                              RxChange               CancelRx
                                                                              Pharmacies             Pharmacies
                                                                              • Enabled = 70%        • Enabled = 85%
                                                                              • Active = 28%         • Active = 80%

                                                                              Prescribers            Prescribers
                                                                              • Enabled = 52%        • Enabled = 72%
                                                                              • Active = 24%         • Active = 44%

                                                                                       Current as of August 2021

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Understanding the Updated SCRIPT National E-prescribing Standard

     WHAT’S NEW?

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19

                                                               NEW SCRIPT
                                                                 MESSAGE
                                                                             NewRx-
                                                                             Request

                                                                    TYPES            RxTransfer

                                                                                Plus
                                                                               LTPAC,
                                                                             REMS, and
                                                                                 P/A
        These new SCRIPT messages are optional at this
     time, so they haven’t yet been implemented by all
                 health information technology vendors

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20

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Understanding the Updated SCRIPT National E-prescribing Standard

     NEWRX REQUEST
     • PHARMACIST TO PRESCRIBER MESSAGE

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21

                                     NEWRX REQUEST

                                        Function
                                                                              Use Case Examples
                                      • Pharmacist to prescriber
                                      • Allows a pharmacist to send a         • New therapy
                                        request for a new prescription        • Patient goes to new pharmacy
                                      • Prescriber responds with either a     • Never filled and expired
                                        NewRx or a denial                     • Regularly gets refills but expired
                                                                              • Original pharmacy closed

                                                                              Value
                                                                              • Patient satisfaction – directly
                                                                                address patient need/request
                                                                              • Eliminate manual workflows at
                                                                                pharmacy (call or fax from
                                                                                pharmacist to prescriber)
                                                                              • Improved adherence

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NABP Webinar – September 15, 2021

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Understanding the Updated SCRIPT National E-prescribing Standard

     RXTRANSFER
     • BIDIRECTIONAL MESSAGES BETWEEN PHARMACISTS/PHARMACIES

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                                     RXTRANSFER
                                         Function                                  Use Case Examples
                                        • Pharmacist to pharmacist                 • Patient moved/on vacation
                                        • Pharmacist requests the transfer of      • Patient went to incorrect location
                                          a prescription (i.e., “pulls” the eRx;   • Change in patient preference
                                          a “push” option is in development)       • Medication out of stock
                                        • Provides an “ALL” Option

                                                                                   Value
                                                                                   • Satisfy the patient – directly
                                                                                     address patient need/request
                                                                                   • Provides significant
                                                                                     improvements in the efficiency
                                                                                     and accuracy of the transfers of
                                                                                     prescriptions
                                                                                   • Minimizes manual workflows at
                                                                                     pharmacy (call or fax from
                                                                                     pharmacy to pharmacy)
                                                                                   • Method to forward a C-II
                                                                                     medication in certain situations
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NABP Webinar – September 15, 2021

                                                                                                                          12
Understanding the Updated SCRIPT National E-prescribing Standard

                                                                          • “Pull” contrasted with “push”
                                                                            use cases

                                                             RXTRANSFER   • Telephone contact between
                                                                            pharmacists might still be
                                                                            necessary
                                                                NUANCES   • Suitability for transfers of e-
                                                                            prescriptions for controlled
                                                                            substances

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                                                                          • Pharmacist and
                            REMINDER:                                       prescriber end-user
                                                                            requests to pharmacy
      THE NEWRX REQUEST & RXTRANSFER                                        technology and
     MESSAGES ARE OPTIONAL, SO NOT ALL                                      electronic health
                                                                            record (EHR) vendors
       VENDORS HAVE IMPLEMENTED THEM                                        are therefore very
                                                                            important

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Understanding the Updated SCRIPT National E-prescribing Standard

     CPE BONUS…

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27

                                                                             BONUS IN-DEPTH
                                                                             INFORMATION
                                                                             (PLUS, CPE CREDIT!)
                                                                             For those interested in
                                                                             more information on the
                                                                             industry’s transition to the
                                                                             new version of SCRIPT, a
                                                                             continuing pharmacy
                                                                             education (CPE) article
                                                                             was published in the
                                                                             November 2019 issue of the
                                                                             National Community
                                                                             Pharmacists Association’s
                                                                             (NCPA) monthly journal,
                                                                             America’s Pharmacist. CPE
                                                                             credit is available for
                                                                             reviewing this article
                                                                             through November 1, 2022.

                                                                             The article is attached at
                                                                             the end of this handout.

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Understanding the Updated SCRIPT National E-prescribing Standard

     SELF-ASSESSMENT QUESTIONS

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     QUESTION #1

     The health information technology industry (HIT) moves to a new version of the NCPDP SCRIPT
     Standard when:
        a. NCPDP’s staff has decided that the time has come.
        b. The Secretary of HHS adopts a new SCRIPT version via CMS rulemaking.
        c. A sufficient number of prescriber and pharmacy HIT end users petition Congress.
        d. None of the above.

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NABP Webinar – September 15, 2021

                                                                                                   15
Understanding the Updated SCRIPT National E-prescribing Standard

     QUESTION #2

     NCPDP SCRIPT Version 2017071 has updated the e-prescribing process by:
      a. Incorporating new or enhanced features to existing message types.
      b. Adding new message types to meet previously unrecognized needs.
      c. Deleting several message types to make room for expanded e-prescribing functionalities.
      d. Both a. and b. are correct.
      e. Both b. and c. are correct.

      31   Copyright © 2020 by Surescripts, LLC. All rights reserved.

31

     QUESTION #3

     Which of the following is not true regarding SCRIPT 2017071:
      a. RxChange and CancelRx messages are new with this version.
      b. NewRx Requests and RxTransfer messages are new with this version.
      c. Some e-prescribing message types are not mandatory for e-prescribing participants.
      d. Two of its most significant improvements are the expanded Sig field and the ability to transmit
         compounded prescription information.

      32   Copyright © 2020 by Surescripts, LLC. All rights reserved.

32

NABP Webinar – September 15, 2021

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Understanding the Updated SCRIPT National E-prescribing Standard

                                          SURESCRIPTS QUERY                                     • Increasingly, we are being
                                                                                                  approached by entities

                                              FOR ATTENDEES                                       calling themselves “non-
                                                                                                  dispensing pharmacies” or
                                                                                                  “hubs” that want to
                                                                                                  connect to our network.
                                                                                                • Workflows and business
                                                                                                  models vary, but all want to
                                                                                                  be involved in the flow of
                                                                                                  prescriptions between
     We’re very interested in your perspective if                                                 prescribers and pharmacies.
                                 you have one.                                                  • Neither appear to be
                                                    Ken.Whittemore@Surescripts.com                mentioned specifically in
                                                                                                  most pharmacy board rules.
                                                                                                • Always striving for regulatory
                                                                                                  compliance, we’re
                                                                                                  generally unsure how to
                                                                                                  respond to such requests.

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33

                                                               QUESTIONS?
                                                                       KEN.WHITTEMORE@SURESCRIPTS.COM

                            (REGULATORY IS IN MY TITLE, SO FEEL FREE TO PING ME ANYTIME)

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Understanding the Updated SCRIPT National E-prescribing Standard

                                                                                                       NABP® and NABP
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                                                                                                                                      18
A giant leap: The industry
                                                                                                          CONTINUING
adopts a new version of
the national e-prescribing
                                                                                                         EDUCATION
standard

by Lisa Schwartz, PharmD, RPh;
and Ken Whittemore, Jr., RPh, MBA

  Nov. 1, 2019 (expires Nov. 1, 2022)
  Activity Type: Knowledge-based
  To earn continuing education credit:
  ACPE UAN: 0207-0000-19-398-H04-P;
  ACPE UAN: 0207-0000-19-398-H04-T

  Upon successful completion of this article, the pharmacist should be
  able to:
  1. Discuss how the adoption of a new, updated version and the effective
      date of the national NCPDP SCRIPT e-prescribing standard is deter-
      mined.
  2. Discuss policy and operational aspects that led to rapid growth in
      e-prescribing volume between 2008-2018.
  3. List the new messages in NCPDP SCRIPT 2017071 and several of the
      data elements or codes that will improve data exchange between pre-
      scribers and pharmacists.
  4. Explain the role of independent pharmacies in adopting the full range
      of messages available
                                                                                                               FREE ONLINE CE. To take advantage
  Upon successful completion of this article, the pharmacy technician                                          of free continuing pharmacy educa-
  should be able to:                                                                                           tion (CPE) for this program, pharma-
  1. Discuss how the adoption of a new, updated version and the effective                                     cists and pharmacy technicians must
      date of the national NCPDP SCRIPT e-prescribing standard is deter-                                       achieve a passing score of 70% on
      mined.                                                                                                   the online continuing education quiz
  2. Discuss policy and operational aspects that led to rapid growth in                                       for the program. If a passing score is
      e-prescribing volume between 2008-2018.                                                                  not achieved, one free reexamination
  3. List the new messages in NCPDP SCRIPT 2017071 and several of the                                         is permitted. To take this test, go to
      data elements or codes that will improve data exchange between pre-                                      www.ncpalearn.org. This activity is
      scribers and pharmacists.                                                                                listed under Online Activities. If you
  4. Explain the role of independent pharmacies in adopting the full range                                    have not registered with this site,
      of messages available                                                                                    you must do so before being able to
                                                                                                               access the CE Center. You will receive
                                                                                                               immediate online test results and
                                                                                                               credits will be posted to CPE Monitor
             NCPA® is accredited by the Accreditation Council for Pharmacy Education as a provider             within six weeks. To obtain your CPE
             of continuing pharmacy education. NCPA has assigned 1.5 contact hours (0.15 CEU) of
             continuing education credit to this article. Eligibility to receive continuing education credit   Monitor e-Profile ID, please go to
             for this article expires three years from the month published.                                    www.cpemonitor.com to register.

www.ncpanet.org/ap                                                                                                                                      43
                                                                                                                                                             19
STANDARDS … WHO NEEDS THEM?                                   WHY SO LONG BETWEEN UPDATES?
As it turns out, in this modern world, everyone does.         The members of NCPDP, which includes representatives
They are found everywhere, though most people are             from the pharmacy profession, are constantly working
probably unaware of their existence. For example, how         to make sure that SCRIPT is a complete and responsive
is it that you can buy light bulbs from dozens of different   standard for e-prescribing and related messages that
manufacturers and they all easily fit in your fixtures at     meets the varied professional and business needs of
home? Because there is a national standard that speci-        all users (please see Table 1). You can just imagine the
fies the width, the length, and what the thread pitch on      number of changes packed into an update when the past
a light bulb should be. What about tires? How is it that      seven years have seen rapid adoption of e-prescribing
a variety of tires can fit on countless different vehicles?   due to prescriber use incentives, new data requirements
Standards. Compact discs and DVDs can be played on            to improve patient care, and a preference for codes in-
many different types of hardware. Why? Standards. You         stead of free text to streamline and improve automation.
can send emails, texts, photos, and videos back and           This said, somewhat incongruously, it is not really up to
forth with ease between cellphones, tablets, laptops, and     NCPDP or its members to decide when the industry will
personal computers all because of information technolo-       move to a new version of SCRIPT. Instead, it is actual-
gy standards. And, since 1997, there has been a national      ly the Centers for Medicare & Medicaid Services that
standard available to transmit prescriptions electronical-    makes this decision.
ly from prescribers to pharmacies in the U.S.
                                                              Why is CMS in charge when it comes to deciding which
So what does the national e-prescribing standard look         version of SCRIPT the industry will use? You have to
like? Well, it’s pretty complicated — probably far more       go all the way back to 2003, when the Medicare
complicated than most pharmacists or pharmacy techni-         Modernization Act — also known as Medicare Part D
cians would imagine. After all, the information required      — was enacted. Among the 400 plus pages of the
to be included in prescriptions by most state boards of       MMA, one section on one page gave the Department
pharmacy and the federal Drug Enforcement Administra-         of Health and Human Services secretary the respon-
tion consists of the following:                               sibility for determining which e-prescribing standards
•	The patient’s name and address.                            should be used for Medicare Part D. Given the size of
•	Drug name, strength, and form.                             that program, this effectively means that HHS, through
•	Directions for use, such as the sig.                       CMS, determines which e-prescribing standard is used
•	Number of refills, if any.                                 nationwide. Most recently, in April 2018, in response to
•	The prescriber’s name, address, and license                the industry’s petitions, CMS published a final rule that
     number(s).                                               gave the industry until Jan. 1, 2020, to move to SCRIPT
                                                              2017071, which is what the entire industry is now
Yes, on occasion, regulatory authorities require a bit more   focused upon. (Interestingly, SCRIPT is not the named
than those bullet points on prescriptions, but not to the     standard in the Part D program for electronic prior
extent that it would require several hundred data fields to   authorization, or ePA, which helps explain why ePA
transmit the information. Yet that is easily the number of    solutions have had a harder time in terms of adoption
fields that make up just the new prescription portion of      and utilization.)
the national e-prescribing standard known as SCRIPT.

SCRIPT — which is capitalized but isn’t an acronym — is
the backbone of nationwide e-prescribing. It is a stan-          Table 1: Examples of related messages
dardized set of data elements and codes developed and
maintained by the members of the National Council for
Prescription Drug Programs, or NCPDP. Another way to             Prescriber-initiated:          Pharmacy-initiated:
say it is that there is a group of people from all sides of      • Cancel Rx                   • NewRx request
the e-prescribing world that developed a big set of form         • Census                      • RxChange request
fields and preselected codes used to quickly and accu-           • Drug administration         • Cancel Rx response
rately fill in an electronic form. The currently adopted         • Recertification             • Rx fill
version of this standard is known as NCPDP SCRIPT                • Resupply                    • Rx renewal request
Version 10.6, but on Jan. 1, 2020, the industry will be          • Rx change response          • RxTransfer
adopting the first update in almost seven years                  • Rx renewal response
by moving to NCPDP SCRIPT Version 2017071.

44                                                                                        America’s PHARMACIST | November 2019
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A BRIEF HISTORY OF E-PRESCRIBING                              permitted until 2010, when the DEA published rules permit-
To promote a baseline level of understanding of e-pre-        ting it, and after that about half of the states had to revise
scribing before getting into the substantial upgrades         their statutes and/or regulations to align with those of the
included in SCRIPT 2017071, let’s review the 20-plus          DEA to allow EPCS. This delay in regulatory authorization
years the standard has been available. After a relatively     has meant that at this time slightly fewer pharmacies are
slow first decade, in 2009, Congress enacted MIPPA —          able to accept EPCSs, and prescribers in states without
the Medicare Improvements for Patients and Providers          active EPCS mandate laws lag significantly behind in the
Act — which offered modest financial enticements for          adoption of EPCS (see Table 2). In response, both states
providers to adopt and utilize e-prescribing. Not long        and the federal government are adopting rules that require
thereafter, adoption took a giant leap forward after the      prescribers to adopt e-prescribing. Specifically, 28 states
enactment of the Health Information Technology for            have now enacted legislation that will require e-prescribing
Economic and Clinical Health Act, which offered huge          across the board, e-prescribing for all controlled substances,
incentives for prescribers to adopt electronic health re-     or e-prescribing for just a subset of controlled substances,
cords. All such EHRs were required to include an e-pre-       such as opioids. On the federal side, the SUPPORT for
scribing functionality. HITECH’s goal was to encourage        Patients and Communities Act of 2018 includes a mandate
electronic health information exchange, but the rush          that prescriptions for controlled substances billed to
to comply with the program’s numerous certification           Medicare must be prescribed electronically by Jan. 1, 2021.
requirements translated into some EHR systems being
poorly designed and implemented, the results of which         WINTER IS COMING … BUT FOR PHARMACIES
were often felt downstream in community pharmacies.           RECEIVING E-PRESCRIPTIONS, IT’S A GOOD
Over the past several years, critical performance im-         THING
provement efforts have been directed at correcting such       Let’s now return to the primary subject at hand — the
deficiencies and perfecting the e-prescribing process.        aforementioned January 2020 industry move to the new
                                                              version of the national e-prescribing standard known as
Today, 98 percent of pharmacies and 76 percent of pre-        SCRIPT 2017071. Broadly, the enhancements brought to
scribers have adopted e-prescribing in general, and 96 per-   bear by this version fall into two categories:
cent of pharmacies and 40 percent of prescribers are now      •	The incorporation of new data segments, elements,
enabled for e-prescribing for controlled substance drugs.          and codes to existing messages such as new
E-prescribing for controlled substances, or EPCS, was not          prescriptions (NewRx).

   Table 2: Electronic Prescribing requirements NOW EXIST IN 28 STATES (07/17/2019)

       All prescription electronic
       requirement in effect
       All prescription electronic
       requirement in future
       All EPCS requirement in effect                                                           L
       All EPCS requirement in future

       EPCS subset requirement
       (e.g., opioids) in effect
       EPCS subset requirement
       (e.g., opioids) in future
       EHR EPCS adoption requirement

       eRx/EPCS legislation in progress (L)

   Copyright © 2019 by Surescripts, LLC.
   All rights reserved.                                               Note: CO and MO requirements exclude Schedule V.

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                                                                                                                               21
•	The addition of new messages that allow the ex-               As was mentioned previously, there are many addition-
   change of information not originally contemplated             al improvements contained in the new e-prescribing
   by SCRIPT, such as the ability to transfer electronic         standard, so let’s touch on several more examples
   prescription information between pharmacies (Rx-              from among the hundreds of changes made in SCRIPT
   Transfer).                                                    2017071 in the form of a “lighting round:”
                                                                 • Allergies: A patient’s allergies can be sent using
All told, SCRIPT 2017071 makes hundreds of improve-                   SNOMED codes.
ments to the e-prescribing process, but most of them are         •	  Brand medically necessary: This data element is
not likely of day-to-day interest to pharmacy personnel.              being updated to meet CMS guidelines.
Thus, for the purposes of this discussion, the focus will        •	Codified notes: A brief list of standardized notes,
be on changes that most directly and significantly affect             such as “Needs Appointment,” is being added.
pharmacy practice, some of which pharmacists and                 •	  Do not fill: Prescribers may indicate that the
pharmacy technicians have been wishing would happen                   prescription should not be filled because it is a
for some time.                                                        cover prescription or should be kept on file until the
                                                                      patient requests it.
It might be going out on a limb a bit, but experience            •	  International address: A country code will be
suggests that the first SCRIPT upgrade that should be                 available to support international addresses.
mentioned is that the new standard is designed to ac-            •	  Prescriber identifiers: Additional fields are being
commodate the electronic prescribing of compounded                    added to accommodate multiple prescriber
prescriptions. None of the earlier versions of SCRIPT                 identifiers, such as DATA 2000/NADEAN (the ‘X’
were designed to convey information about compounded                  DEA number).
prescriptions, but as many pharmacists and pharmacy              •	  Primary language: The patient’s preferred language
technicians have experienced, prescribers have often                  can be indicated if other than English, which is use-
tried to shoehorn such information into electronic pre-               ful in general and is a requirement in some states.
scriptions anyway, leading to much confusion among               •	  Prohibit refill requests & follow-up prescriber
those receiving such prescriptions. This should no lon-               information: Prescribers may indicate that they do
ger happen after January 2020, because the new version                not want to receive renewal requests (such as in
of SCRIPT is able to incorporate the drug name and                    the case of emergency rooms or urgent care) and/or
quantity for up to 25 different ingredients in one electron-          they can designate an alternate prescriber for
ic prescription. And if all else fails, for the applications          follow up.
that support it, the compounding pharmacy can request            •	  Substance use: If applicable, the patient’s sub-
a new prescription.                                                   stance abuse history can be shared with pharmacy
                                                                      personnel.
Another component of electronic prescriptions that has           •	  Urgent Rx: Allows a prescriber to request expedited
been problematic for pharmacy personnel over the                      dispensing of a particular prescription.
years is the sig, or patient instructions, field. All previous   •	  Weight: Not new, but frequently requested, a
versions of SCRIPT have limited the length of this field              patient’s weight can be sent in kilograms in the
to 140 characters, which in many cases was insufficient               “Observation” field.
for prescribers to express their instructions to patients
as they wished. This, too, often led to confusion and            All of these examples are considered to be of special
delays in pharmacies, requiring pharmacy personnel to            interest to pharmacy personnel, but please be advised
reach out to prescribers to clarify what they meant. To          that this list represents only a small portion of what is in
address this e-prescribing challenge, NCPDP members              store in the new version of the e-prescribing standard.
approved a sig field expansion to 1,000 characters
in SCRIPT 2017071. Hopefully there will be very few              Now let’s look at just a couple of the entirely new
instances in which a prescriber will actually use all 1,000      messages being introduced in SCRIPT 2017071. As was
characters available to write a sig, because that would          mentioned earlier, these messages deal with unmet
cause a different type of problem at the pharmacy end            needs that earlier versions of the e-prescribing standard
(think about trying to fit all of that on a prescription         did not anticipate:
label!), but the added capacity should definitely resolve        •	  RxTransfer: This message is exactly what you
more issues than it causes. It also is anticipated that               would think from its name — it’s an electronic way
pharmacy software vendors will devise methods of han-                 to perform the age-old procedure of transferring a
dling sigs that are toward the higher end of this new limit.          patient’s prescription from one pharmacy to another.

46                                                                                         America’s PHARMACIST | November 2019
                                                                                                                                22
Frankly, it is a little surprising that NCPDP didn’t               it to another pharmacy at the patient’s request. This
  tackle this need earlier, but the oversight will be                is not possible with the version of RxTransfer that
  corrected soon.                                                    currently is being adopted. Once the pharmacy that
	From a workflow standpoint, RxTransfer is modeled                  originally dispensed the prescription receives the
  on the current process in that the pharmacy where                  transfer request, it will send a response with the
  the patient would like to have his or her prescription             prescription information or a response denying the
  filled initiates a message to “pull” the prescription              request (such as the prescription was already trans-
  from the pharmacy that originally dispensed it. It is              ferred, no refills remain, or the prescription was not
  important to understand this point, because there                  found).
  are some in the industry who have the mistaken                   	Additionally, unlike other e-prescribing messages,
  impression that RxTransfer can also be used as a                   this communication takes place solely between
  “push” message, meaning the pharmacy that orig-                    pharmacies, which means that both the receiving
  inally dispensed a prescription can simply forward                 and sending pharmacies must be enabled to handle

   An underutilized e-prescribing message becomes more muscular

   There are multiple reasons why a pharmacist might want to suggest that a prescriber make a change in a patient’s
   prescription, and traditionally such recommendations have been made in verbal or paper form. For many years, however,
   there has been an electronic message available for transmission via the e-prescribing infrastructure that can convey
   change recommendations from pharmacists to prescribers. This message is called RxChange, and thus far the pharmacy
   community has not taken advantage of its functionality to the degree that you might expect. SCRIPT 2017071 significantly
   expands the number of circumstances in which this message can be used, though, so it is hoped that dramatic increases
   in the use of this message will be noted in the future.

   Presently, there are three uses cases available for RxChange:
   •G
     eneric substitution: This is suitable when a new generic becomes available during ongoing treatment, the prescriber
    has indicated dispense as written but the patient still wants a generic, a brand is not covered, a high copay or coinsurance
    makes the brand unaffordable, the patient desires a biosimilar that requires prescriber authorization, or the pharmacy
    does not carry a specific product.
   •P
     rior authorization: It’s used when a pharmacy receives a prescription claim reject indicating that a prior authorization
    number is needed from the prescriber before the prescription will be covered by a patient’s insurance.
   •T
     herapeutic interchange: It’s appropriate whenever a pharmacist determines a change in therapy would benefit the
    patient.

   These are beneficial to be sure, but the industry has added several more valuable use cases in the new version of
   SCRIPT:
   •D
     rug use evaluation: This is applicable when a pharmacist determines there are alternative drugs that could be
    dispensed with fewer adverse effects.
   •S
     cript clarification: This is employed when a pharmacist or pharmacy technician needs clarification to the medication
    information contained in a prescription to be able to dispense it.
   •O
     ut of stock: The pharmacy does not have any of the medication in stock and does not anticipate it will obtain it soon
    enough for the patient.
   •P
     rescriber authorization: This is useful when the pharmacist wishes to confirm the prescriber’s authority to prescribe
    (a limited use case).

   Judging by feedback that has been received from pharmacy personnel over the years, script clarification might end up being
   the most helpful of all of the new RxChange use cases. Pharmacy owners and managers interested in using RxChange for
   this new purpose should reach out to their pharmacy software vendor to ensure that this new feature is going to be made
   available to them with their SCRIPT 2017071 update.

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                                                                                                                                        23
RxTransfer messages. For this to happen, pharma-           and e-prescribing intermediaries have been preparing
  cy software vendors must incorporate RxTransfer            intently for more than a year for CMS’s Jan. 1, 2020
  message capabilities into their applications. Phar-        deadline, and most industry participants should be ready
  macy owners and managers who have an interest in           for the cutover on that date. It is hoped that by sharing
  using RxTransfer messages should therefore have a          information in this article on the most noteworthy new
  conversation with their pharmacy software vendors          features to be delivered by SCRIPT 2017071, practicing
  sharing their interest. Finally, pharmacists must con-     pharmacists and pharmacy technicians will come to
  sider whether such electronic prescription transfers       understand the importance of this critical transition and
  are allowed by their state’s laws and regulations.         will be encouraged to do what they can to participate in
  NewRxRequest: This, too, is a message designed
•	                                                          the process and fully utilize the new and/or enhanced
  to attend to a previously unmet need, although this        technological tools that they will be given. ■
  type of communication is not as commonplace as
  transferring prescriptions. It allows a pharmacist to      Lisa Schwartz is NCPA senior director, professional affairs.
  request a new prescription from a prescriber with ei-      Ken Whittemore is Surescripts vice president of professional
  ther minimal information or expired prescription in-       and regulatory affairs. Questions of a technical nature should be
  formation. For example, a patient might come to the        sent to Whittemore at ken.whittemore@surescripts.com.
  pharmacy saying that his or her physician was going        Other questions may be sent to lschwartz@ncpanet.org.
  to send a prescription for an antibiotic to the phar-
  macy, but no such prescription is in the pharmacy’s
  records. In this case, a NewRxRequest can be sent
  to the prescriber indicating simply that the patient
  has requested an antibiotic, and then the prescriber
  can respond as they see fit. Another possible use
  for this transaction is related to prescriptions for
  which patients have an ongoing — yet very intermit-
  tent — need, such as allergy medications or asthma
  inhalers. If a patient’s prescription is too old, or the
  information about the prescription is incomplete, a
  NewRxRequest will probably be the best choice to
  attempt to attend to the patient’s medication need.

Again, similar to the data elements mentioned earlier,
these are just two out of the 10 new messages made avail-
able by SCRIPT 2017071, but they are likely the ones that
will be of the greatest interest to pharmacy personnel.

TAKING ADVANTAGE OF ALL THAT SCRIPT
2017071 HAS TO OFFER
The adoption and utilization of e-prescribing over the
past two decades has delivered on much of the technol-
ogy’s promise of increased accuracy and safety, greater
pharmacy and prescriber efficiencies, more robust
communication between medical professionals, and
reduced costs. This said, as is the case with virtually
every modern technology, regular updates are critical to
maintaining relevance, delivering enhanced capabilities,
and yes, remediating deficiencies and imperfections.

Because the industry is constrained by federal require-
ments in terms of how often it can move to new versions
of the SCRIPT standard, it is that much more important
that maximum utility and value are wrung out of every
upgrade. EHR vendors, pharmacy software vendors,

48                                                                                      America’s PHARMACIST | November 2019
                                                                                                                                 24
CE
     QUIZ

Continuing Education Quiz                                    7. Which federal legislation was most responsible for
Select the correct answer.                                   stimulating the adoption of e-prescribing in the U.S.?
                                                             a. Health Information Technology for Economic and
1. The SCRIPT standard is used to transfer data between          Clinical Health Act
which of the following:                                      b. Medicare Improvements for Patients and Providers Act
a. Prescribers and pharmacies                               c. SUPPORT Act for Patients and Communities of 2018
b. Pharmacies and PBMs                                      d. None of the above
c. Pharmacies and LTC facilities
d. Prescribers and PBMs                                     8. Currently, at the national level, what percent of phar-
e. All of the above                                         macies and prescribers are enabled for e-prescribing in
                                                             general?
2. Starting Jan. 1, 2020, pharmacies should not fill paper   a. 55 percent of pharmacies and 27 percent of prescribers
prescriptions for controlled substances for Medicare         b. 72 percent of pharmacies and 52 percent of prescribers
patients.                                                    c. 98 percent of pharmacies and 76 percent of prescribers
a. True                                                     d. 100 percent of pharmacies and 95 percent of
b. False                                                        prescribers

3. Which federal agency is responsible for determining       9. As of September 2019, what number of states have
which e-prescribing standard is used for the Medicare        adopted mandates requiring e-prescribing in general,
Part D program?                                              e-prescribing for controlled substances, or e-prescribing
a. Food and Drug Administration                             for a subset of controlled substances?
b. Center for Medicare & Medicaid Services                  a. Eight
c. National Institute of Standards and Technology           b. 15
d. Federal Communications Commission                        c. 22
                                                             d. 28
4. The NCPDP SCRIPT standard is only capable of trans-
mitting data that is required by state boards of pharmacy    10. The new version of the NCPDP SCRIPT standard will:
and Drug Enforcement Administration regulations.             a. Incorporate new data segments, elements, and codes
a. True                                                        to existing messages such as new prescriptions.
b. False                                                    b. A dd new messages that allow the exchange of
                                                                 information not originally contemplated by SCRIPT.
5. It has been approximately ___ years since the industry    c. B
                                                                 oth of the above
has moved to a new version of the NCPDP SCRIPT               d. B oth of the above, but (a) will occur one year before
standard for e-prescribing?                                      (b)
a. Two
b. Three                                                    11. Which of the following is true with respect to
c. F
    ive                                                     NCPDP SCRIPT Version 2017071?
d. Seven                                                    a. Compounded prescriptions will finally be properly
                                                                transmitted using e-prescribing.
6. The NCPDP SCRIPT standard includes many types of          b. T he sig field will be expanded from 140 to 1,000
messages in addition to new prescriptions.                       characters.
a. True                                                     c. A
                                                                 patient’s primary language will be transmittable.
b. False                                                    d. A ll of the above

                                                              Continued on page 50

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                                                                                                                           25
12. The new version of the NCPDP SCRIPT Standard will                            14. The NewRxRequest message is sent by patients to
include the ability to indicate “Do Not Fill” and “Urgent                        their prescriber when they would rather not schedule a
Rx” in an e-prescription.                                                        face-to-face encounter.
a. True                                                                         a. True
b. False                                                                        b. False

13. Which of the following is true regarding the new                             15. Of the currently available NCPDP SCRIPT standard
NCPDP SCRIPT standard message known as RxTransfer:                               messages, which is the least utilized:
a. U
    nlike the current telephone method of transferring                          a. New prescriptions
   prescriptions, it is a “push” message.                                        b. Refill renewal requests
b. This new message can be used to transfer prescriptions                       c. Prescription change requests
   between pharmacies and from pharmacies to payers                              d. Prescription cancellations
   and pharmaceutical companies.
c. T
    he receiving pharmacy must accept an RxTransfer                             16. The new RxChange (prescription change request) use
   when it is “pushed” to it.                                                    case that will likely be of most value to pharmacists is:
d. P harmacists must ascertain whether their state’s rules                      a. Drug use evaluation
    allow the electronic transfer of prescriptions prior to                      b. Script clarification
    using RxTransfer.                                                            c. Out of stock
                                                                                 d. Prescriber authorization

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