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Conference Program
PARTNERS & SPONSORS
date
Up
Biomanufacturing Symposium
EU BIOTECH DAYS
Industrial Biotechnology
Innovation Forum
Life Science Spotlight
Partnering
YOUR CONTACT
Science to Market
Carola Triebsch Lühr Schneider
Tel. +49 511 89-31139 Tel. +49 511 89-32169
carola.triebsch@messe.de luehr.schneider@messe.de
CONFERENCE REGISTRATION
Andrea Busch Jens Bürger
Tel. +49 511 89-33575 Tel. +49 511 89-31338
Tel. +49 511 89-31348 Tel. +49 511 89-31349 www.bioperspectives.org
andrea.busch@messe.de jens.buerger@messe.de
Deutsche Messe
Messegelände
Hannover | Germany
30521 Hannover 7–9 October 2008
Germany
Fax +49 511 89-31218 International Trade Fair, Conferences,
biotechnica@messe.de Partnering and Award for Biotechnology
www.biotechnica.de www.biotechnica.deVeranstaltungen BIOTECHNICA 2008 Conditions for Participation / Organizational information
Willkommen zur BIOTECHNICA 2008!
BIOTECHNICA Conferences 2008
Das Konferenzprogramm der BIOTECHNICA 2008 gliedert sich in die Themen: ORGANIZERS: Registration Please submit one registration form per
DECHEMA e.V. DECHEMA e.V. formalities participant. To register, use the enclosed
Science & Business mit Europas wichtigstem Biotechnologie-Kongress, den EUROPEAN BIOPERSPECTIVES sowie registration form or register online at
Theodor-Heuss Allee 25
dem Kongress “Science to Market”. http//:www.biotechnica.de/con
60468 Frankfurt am Main – Germany
BioBusiness u.a. mit dem BIOTECHNICA PARTNERING und dem BIOTECHNICA INNOVATIONS-FORUM Matthias Neumann Tickets and You will also receive your trade fair admission
(dieses Jahr erstmals direkt im Ausstellungsbereich der Halle 9). Phone: +49 69 7564 254 documents ticket (if ticket is included) with your confirma-
Email: neumann@dechema.de tion of participation.
BioPolitics ist mit zwei hochkarätigen Veranstaltungen in Zusammenarbeit mit der Europäischen Kommission und You will receive your name badge and other
dem Europäischen Parlament vertreten. Die Biopolitik-Konferenz (vormals Deutsche Biotechnologietage) gibt am EAPB European Association of documents in the foyer of the Convention Cen-
1. Messetag den Auftakt des umfangreichen Konferenzprogramms. Pharma Biotechnology ter (CC) at the “Registration Desk”.
Kelchstr. 31 Last minute To avoid waiting times, we ask you that you
Über 400 exzellente Referenten werden im Convention Center und in den Ausstellungshallen aktuelle Trends und 12169 Berlin – Germany
Forschungsergebnisse sowie erfolgreiche Anwendungen aus der Praxis präsentieren. registration register at least 45 minutes before the start of
the event.
Conference Project Manager:
Wichtige Hinweise für den Besucher: Dr. Inge Mühldorfer Payment Payment of registration fees can be made by:
Konferenzsprachen: Phone: +49 7392 701252 Bank transfer
Email: inge.muehldorfer@rentschler.de After your registration has been received, you
• Die Vortragssprache aller Vorträge geht aus der Sprachfassung des jeweiligen Titels hervor, deutsch und/oder englisch. will receive an invoice requesting you to trans-
BioM WB GmbH BioM WB GmbH fer the amount to one of the accounts which is
• Sofern nicht anders gekennzeichnet, ist die Teilnahme an den Vortragsveranstaltungen für alle BIOTECHNICA-
Am Klopferspitz 19 mentioned on the invoice. Please do not fail to
Besucher kostenfrei. quote the invoice number and the “name of
82152 Martinsried – Germany
Wir wünschen Ihnen einen erfolgreichen Messeaufenthalt! Besuchen Sie unsere vier Veranstaltungssäulen Prof. Dr. Haralabos Zorbas the conference.”
Ausstellung.Konferenzen.Partnering.Award! Phone: +49 89 899679-26 Credit card
Email: zorbas@bio-m.org For payments by credit card, the credit card
company, number, and expiration date must
CapGemini Capgemini Deutschland GmbH be marked on the registration form. The re-
Life Sciences ceipt will be sent to you with the invoice. For
Events at BIOTECHNICA 2008 Löffelstr. 44-46 registration at the event, the registration fee
70597 Stuttgart – Germany has to be paid by credit card.
Dr. Jan Farfsing
Welcome to BIOTECHNICA 2008! Phone: +49 711 50505-137 Cancellation € 20 administrative costs will be charged for
Email: jan.farfsing@capgemini.com cancellations before 15 September 2008.
The conference program of BIOTECHNICA 2008 is divided into the following themed segments: Thereafter 80 % of the registration fee will be
Science & Business, featuring Europe’s foremost biotech congress, EUROPEAN BIOPERSPECTIVES, plus the BiomeTI e.V. BiomeTI e.V. invoiced. Cancellations need to be made in
Garbsener Landstr. 10 writing (email, letter or fax). Refunds are not
“Science to Market” conference.
30419 Hannover available for trade fair admission tickets that
BioBusiness, featuring the revamped BIOTECHNICA PARTNERING and the BIOTECHNICA INNOVATION FORUM Dr.-Ing. habil. Andreas Ostendorf have already been purchased. Admission
(now located right on the exhibition floor in hall 9) and more . . . Phone: +49 511 2772810 tickets already dispatched must be returned to
Email: info@biometi.de Deutsche Messe AG.
BioPolitics, featuring a rich conference program including two high-caliber events being staged in collaboration with
the European Commission and the European Parliament: The Biopolitics Conference (formerly Services – Participation in the congress on the event
Deutsche Messe AG Deutsche Messe AG days as reserved
“Deutsche Biotechnologietage”) will get the program rolling on day on of BIOTECHNICA. Messegelände – Participation pack (different to each
At the Convention Center and in the exhibition halls more than 400 top-flight speakers will be talking about current 30521 Hannover – Germany congress/ conference)
trends and research findings, as well as successful practical applications. Carola Triebsch – Drinks during coffee breaks
Phone: +49 511/89 31139 – Trade fair admission ticket
Email: carola.triebsch@messe.de – Participation in sessions, workshops and
Important information for visitors supporting program as booked
Conference Language REGISTRATION FOR:
REGISTRATION
• The language of all events is revealed by their titles Deutsche Messe AG will handle the registrations for
– English title = lecture in English the following conferences: Contact
– German title = lecture in German European BioPerspectives 2008 Deutsche Messe AG Deutsche Messe AG
– English and German title = simultaneous translation On behalf and the account of DECHEMA e.V Nevin Bozkurt Vesna Koch
Sonja Wicke Niki Ohler
• Unless otherwise specified, admission is free of charge to all BIOTECHNICA fairgoers. Science to Market – EAPB Conference Tel. +49 511/89-3 13 48 Tel. +49 511/89-3 13 38
On behalf and the account of EAPB Tel. +49 511/89-3 13 49 Tel. +49 511/89-3 35 75
Have a great time at the fairground and visit our four event columns Exhibition. Conferences. Partnering. Award!
Biopolitics Conference nevin.bozkurt@messe.de vesna.koch@messe.de
On behalf and the account of Deutsche Messe AG sonja.wicke@messe.de niki.ohler@messe.de
Biomanufacturing Symposium
On behalf and the account of Deutsche Messe AG VENUE Convention Center (CC)
BIOTECHNICA PARTNERING Messegelände
On behalf and the account of Deutsche Messe AG 30521 Hannover – Germany
EU BIOTECH DAYS Program of the The organizers reserves the right to
Participation free of charge to BIOTECHNICA ticket holders conferences make changes to the program.
Foundation of Spin-Offs and Exit Strategies in the
White Biotechnology
On behalf and the account of BioM WB GmbH
BiomeTI Roadshow
On behalf and the account of BiomeTI e.V.
105BioScience
Science & Business
Science to Market – EAPB Conference (07.–08.10.2008) 2–4
European BioPerspectives 2008 (07.–09.10.2008) 5–54
– REBIRTH-Conference
BMBF-Projektforum Biotechnologie (07.–09.10.2008) 55
BioPolitics
BioPolitik-Konferenz (07.10.2008) 63
EU BIOTECH DAYS (I) – Conference of the European Parliament (07.10.2008) 65
EU BIOTECH DAYS (II) – Conference of the European Commission (08.10.2008) 67
BioBusiness
Miniaturisierte Biosystemtechnik: Innovation für Dignostik & Pharma (06.–07.10.2008) 69
BIOTECHNICA INNOVATION FORUM (07.–09.10.2008) 72
BIOTECHNICA PARTNERING (07.–09.10.2008) 80
Forum: Problemlösungen aus Baden-Württemberg (07.–09.10.2008) 81
German-Russian Workshop Biotechnology (07.10.2008) 84
jobvector-Karrierestand (07.–09.10.2008) 86
Life Science Spotlight (07.–09.10.2008) 86
Neue Märkte: Ein Tool im Strategieprozess (07.10.2008) 89
Biomanufacturing Symposium (08.10.2008) 91
VBU BioBusiness Forum (08.10.2008) 93
Ausgründungs- und Exit-Strategien in der Weißen Biotechnologie (09.10.2008) 94
BiomeTi Roadshow (09.10.2008) 96
jobvector-check (09.10.2008) 98
jobvector-Forum (09.10.2008) 98
jobvector-jobtour (09.10.2008) 100
General Information BIOTECHNICA 2008 101
Map of Exhibition Ground 103
Convention Center 104
Conditions for Participation BIOTECHNICA Conferences 105
Status as of 26 September 2008 / Program subject to change.Science & Business
1“Science to Market” – EAPB Conference Dienstag/Tuesday, 07.10.2008
08:30–09:00 Registration in the foyer of Convention Center
Convention Center (CC), Saal/Room 1 A, 11, 12
“Registration Biotechnica Conferences”
07.10.2008, 08:30–21:00 Uhr/hrs
08.10.2008, 08:30–15:00 Uhr/hrs Room 1 A
09:00–09:15 Welcome, Introduction and Opening remarks
Erstmalig richtet die EAPB in Zusammenarbeit mit der BioPerspectives die Konferenz „Science Wieland W. Wolf, President of the EAPB, Rentschler Biotechnologie GmbH,
to Market“ aus. Ziel des europäischen Events ist die Förderung der Zusammenarbeit von Laupheim (D)
Wissenschaft und Industrie im Bereich der pharmazeutischen Biotechnologie, um die
09:15–10:00 Keynote Lecture: “Rational protein design – In vitro evolution of
Weiterentwicklung von kommerzialisierbaren Technologien und Produkten voranzutreiben. Im
antibody therapeutics”
Fokus stehen neue biopharmazeutische Arzneimittel- und Diagnostik-Entwicklungen sowie
Andreas Plückthun, University of Zurich (CH)
innovative Technologien.
10:00–10:15 Coffee Break
For the first time EAPB organizes in cooperation with BioPerspectives the conference “Science
to Market”. The goal of this European event is the promotion of collaborations between science Workshop 1: “Therapeutics and diagnostics“ – Room 11
and industry in the area of pharmaceutical biotechnology to enhance the economical output of
Moderation: Inge Mühldorfer, Rentschler Biotechnologie GmbH, Laupheim (D)
scientific research and direct them into marketable technologies and products. The conference
focuses on biopharmaceutical drug and diagnostic developments and novel technologies for 10:15–10:45 Immune therapy against Alzheimer’s disease
the development and production Richard Dodel, Philipps-University Marburg (D)
10:45–11:15 Gene diagnostics as a tool for individualized medicine
Veranstalter/ European Association of Pharma Biotechnology Johannes Oldenburg, University Clinic Bonn (D)
Organizer Conference Project Manager:
11:15–12:30 Oral poster presentations:
Inge Mühldorfer (contact see below)
(1a) Novel biopharmaceuticals and diagnostics
in cooperation with:
European BioPerspectives 2008 Workshop 2: “Novel technologies“ – Room 12
Sprache/ Englisch/English Moderation: Wieland W. Wolf, Rentschler Biotechnologie GmbH (D)
Language
10:15–10:45 Beyond immunotoxins: Human fusion proteins for tumor therapy
Teilnahme/ Participation fee (no VAT requested according to § 4.22 UStG). Stefan Dübel, Technical University of Braunschweig (D)
Participation 10:45–11:15 The Emerging therapeutic concept of nanobodies
Member of EAPB/EFB: Non-Member: Paul van Bergen en Henegouwen, Utrecht University (NL)
455,00 EUR (Industry) 470,00 EUR (Industry) 11:15–12:30 Oral poster presentations:
195,00 EUR (Academia) 210,00 EUR (Academia (2a) Novel biopharmaceutical drug formats
40,00 EUR (Students) 55,00 EUR (Students)
12:30–14:00 Lunch Break in hall 9 (Lunch is not included in the participation fee)
The conference fee includes Workshop 1: “Therapeutics and diagnostics“ – Room 11
– Participation on October 7 and 8, 2008
– Trade fair admission tickets Moderation: Henrik L. Luessen, Tytonis BV, Alkmaar (NL)
– Coffee breaks 14:00–14:30 Role of toxicogenomics in preclinical drug safety assessment
– BIOTECHNICA Night Roy Forster, International Toxicology Centre CIT, Evreux (F)
– Social event on October 7, 2008 14:30–15:00 Transient PEGylation technology – Preserving the original
Registration required via Deutsche Messe with pharmacology of protein
“REGISTRATION FORM BIOTECHNICA CONFERENCES 2008” online at Dirk Vetter, Ascendis Pharma GmbH, Heidelberg (D)
http//:www.biotechnica.de/con or at the “Registration-desk” in the
15:30–17:00 Oral poster presentations:
Convention Center
(1a) Novel biopharmaceuticals and diagnostics
Conditions for participation and general information see program on (1b) 2nd generation biopharmaceuticals
pages 101
Kontakt/ Contact Inge Mühldorfer Workshop 2: “Novel technologies“ – Room 12
Telefon: + 49 7392 701-252 Moderation: Karoline Bechtold-Peters, Boehringer-Ingelheim Pharma GmbH & Co. KG,
Fax: + 49 7392 701-220 Biberach an der Riss (D)
E-mail: inge.muehldorfer@rentschler.de 14:00–14:30 Innovative upstream processing technologies for the efficient
production of therapeutics
Karl Bayer, University of Natural Resources and Applied Life Sciences,
Vienna (A)
2 314:30–15:00
15:00–15:30
Novel expression system based on Ciliates of the species
Tetrahymena for the production of therapeutic proteins
Marcus Hartmann, Cilian AG, Münster (D)
Coffee Break
2008
2 0 0 8
15:30–17:00 Oral poster presentations:
Foyer Room 1
17:00–18:30
(2b) Novel up-and downstream developments
Networking at poster boards
European
Room 2
18:30–19:15 Special Keynote Lecture:
“Future perspectives on stem cell research”
BioPerspectives
in co-operation with BIOTECHNICA 2008
B I O P E R S P E C T I V E S
Stephen Minger, King´s College London (UK)
Room 3
19:30–21:00 Social Event
Mittwoch/Wednesday, 08.10.2008
08:30–09:00 Registration in the foyer of Convention Center
“Registration Biotechnica Conferences”
Room 1 A
09:00–09:45 Keynote Lecture:
“Gene therapy – balancing toxicity and efficiency”
Christopher Baum, Medical School Hannover (D)
09:45–10:00 Coffee Break
Workshop 1: “Therapeutics and diagnostics“ – Room 11
Moderation: Heiko E. von der Leyen, Hannover Clinical Trial Center GmbH, Hannover (D)
10:00–10:30 Vaccination against high blood pressure
Patrik Maurer, Cytos Biotechnology AG, Schlieren (CH)
10:30–11:00 Mucosal immunization using DNA vaccines
Gerrit Borchard, University of Geneva, Geneva (CH)
11:00–12:15 Oral poster presentations:
(1c) Novel vaccines and gene therapy developments
Workshop 2: “Novel technologies“ – Room 12
Moderation: Barry D. Moore, XstalBiol, Glasgow (UK)
10:00–10:30 Nanotechnology applications in nano medicine
Elena Martinez Fraiz, Institute for Bioengineering of Catalonia – IBEC,
Program
Barcelona (ES)
10:30–11:00 Exploiting precipitation and crystallization of monocional antibo-
dies for drug development E U R O P E A N
Karoline Bechtold-Peters, Boehringer Ingelheim Pharma GmbH & Co. KG,
Biberach/Riss (D)
11:00–12:15 Oral poster presentations:
(2c) Novel biopharmaceutical drug delivery and analytical tools
Room 1 A
12:15–12:45 Panel discussion and closing remarks
Foyer Room 1
12:45–15:00 Networking at poster boards
w w w. b i o p e r s p e c t i v e s . o r g
4European BioPerspectives 2008 CONTENTS
Convention Center (CC), Room 2 (Plenary Lectures)
07.10.2008, 13:30–21:00 Uhr/hrs / 08.10.2008, 09:00–17:30 Uhr/hrs
09.10.2008, 09:00–17:20 Uhr/hrs
Die EUROPEAN BIOPERSPECTIVES 2008 ist der 4. Biotechnologie-Fachkongress, der EUROPEAN BIOPERSPECTIVES 2008
21 Fachgesellschaften und Organisationen aus Biowissenschaften und Biotechnologie in dem
Ziel vereint, ein aktuelles und anspruchsvolles wissenschaftliches Vortragsprogramm anzu- Page
bieten. Die Partner repräsentieren zusammen rund 30.000 individuelle Mitglieder. Das wissen-
schaftliche Komitee setzt sich aus renommierten Fachvertretern zusammen, die hohe Qualität ■
SCIENTIFIC COMMITTEE 8
und thematische Breite des mehrsträngigen Programms gewährleisten.
European BioPerspectives 2008 is the fourth conference of this format which unites 21 major ■
WELCOME TO EUROPEAN BIOPERSPECTIVES 2008 9
biotechnology and biosciences organisations in presenting an excellent scientific program
from many areas of research. The partners have a total of 30,000 individual members. The PROGRAM AT A GLANCE 10
■
scientific committee consists of renowned experts who take care of the high quality and
diversity of the multi-session program.
■
PLENARY LECTURES 16
Veranstalter/ DECHEMA – Gesellschaft für Chemische Technik und Biotechnologie e.V.
Organizer Theodor-Heuss-Allee 25 ■
KEYNOTE LECTURES 17
D-60486 Frankfurt
(for organizers see pages 38 pp) ■
PROGRAM
Sprache/ Englisch/English
Language
Tuesday, October 7 20
Wednesday, October 8 24
Teilnahme/ Participation fee (no VAT requested according to § 4.22 UStG.)
Participation Member:* Non-Member: Thursday, October 9 32
Full Conference Pass Industry 580,00 EUR 595,00 EUR
Academia 250,00 EUR 265,00 EUR ■
ORGANIZATIONS 38
Students 40,00 EUR 55,00 EUR
2 Day Ticket Industry 455,00 EUR 470,00 EUR ■
POSTER SESSIONS 46
Academia 195,00 EUR 210,00 EUR
1 Day Ticket Industry 265,00 EUR 280,00 EUR ■
POSTER PROGRAM 46
Academia 100,00 EUR 115,00 EUR
*Personal member of one of the organizing societies of European BioPerspectives
■
GENERAL INFORMATION 54
The conference fee includes:
– Participation in the congress on the event days as reserved SOCIAL PROGRAM 54
■
– List of participants
– Book of abstracts
– BIOTECHNICA Night
– Drinks during coffee breaks
– Trade fair admission ticket(s)
– Poster party on October 7, 2008
Registration required via Deutsche Messe with “REGISTRATION FORM
BIOTECHNICA CONFERENCES 2008” online at http//:www.biotechnica.de/con,
or at the Registraion desk in the Convention Center
Kontakt/ Contact Matthias Neumann/Dr. Karsten Schürrle October 7–9, 2008,
Telefon: +49(0)69 7564-254 /-162 Telefon:+49 511 8608212
E-mail: contact@bioperspectives.org E-mail: neumann@dechema.de
6
EUROPEAN BIOPERSPECTIVES 2008 7COMMITTEE INVITATION
■
S CIE N T I F I C CO M M IT T E E ■■ Welcome to European BioPerspectives 2008!
Thomas Altmann Golm Since last year’s conference biotechnology has seen a lot
Rudi Balling Braunschweig of developments:
Ulrich Behrendt Sindelsdorf VBIO – German Life Sciences Association, founded du-
Uwe Bornscheuer Greifswald ring European BioPerspectives 2007, has since then
Erwin Flaschel Bielefeld taken up its full activities now representing more than
T. Scheper R. Balling
Ronald Frank Braunschweig 35.000 individual members from the life sciences area in
Bernward Garthoff Leverkusen Germany.
Hinrich Harling Einbeck
Hansjörg Hauser Braunschweig We have seen the European Commission’s 7th Framework Program starting with the first calls.
Stefanie Heiden Osnabrück IMI – the Innovative Medicines Initiative, a joint venture of the European Commission and EFPIA
Manfred Kircher Marl – European Federation of Pharmaceutical Industries and Associations, just has launched its first
Konrad Kohler Tübingen call. The German BioIndustry 2021 Clusters started their activities and the national BioPharma
Christine Lang Berlin program was announced. We have seen new products coming to the market and new facilities
Hans Lehrach Berlin starting their production. Substantial progress has been made in many science areas, offering
Andreas Liese Hamburg new chances for new products in different industrial applications.
Friedrich Lottspeich Martinsried
Ulrich Martin Hannover Learn about all these developments at European BioPerspectives 2008!
Heike Mertsching Stuttgart
Hans-Peter Meyer Visp (Switzerland) This year, European BioPerspectives visits Hannover, one of Northern Germany‘s biotechno-
Beat Mollet Lausanne (Switzerland) logy capitals with a large number of research institutes, universities and companies. Hannover
Peter Nürnberg Cologne is well known among biotechnologists because it is home of BIOTECHNICA, Europe’s most
Dietmar Peters Gülzow important annual biotechnology trade show.
Jörn Piel Bonn With the decision to move to Hannover this year the 21 partner organizations of European
Alfred Pingoud Giessen BioPerspectives agreed to have both events in parallel.
Alfred Pühler Bielefeld The result will be an event with a new dimension for Europe: the full diversity of biotechnology
Oscar-Werner Reif Göttingen in one place at a time!
Carsten Roller Munich
Felicia Rosenthal Freiburg We are looking forward to welcoming you to Hannover.
Thomas Scheper Hannover
Andreas Schmid Dortmund
Dietmar Schomburg Braunschweig
Andreas Schütte Gülzow
Thomas Scheper Rudi Balling
Helmut Schwab Graz (Austria)
Chairman of DECHEMA Biotechnology Chairman of VBIO
Arne Skerra Freising-Weihenstephan
Konrad Soyez Wilhelmshorst
Roland Ulber Kaiserslautern
Dirk Weuster-Botz Garching
Wolfgang Wiechert Siegen
8 EUROPEAN BIOPERSPECTIVES 2008 EUROPEAN BIOPERSPECTIVES 2008 9TUESDAY, OCTOBER 7, 2008 PROGRAM AT A GLANCE PROGRAM AT A GLANCE TUESDAY, OCTOBER 7, 2008
Science to Market
organized by EAPB –
European Association of Pharma
Biotechnology
8:30 Registration
9:00 Room 1A Welcome
W. Wolf
9:15 Room 1A KEYNOTE
A. Plückthun
10:00 Coffee break
Room 11 Room 12
10:15 R. Dodel S. Dübel
10:45 P.M.P. van Bergen en
J. Oldenburg
Henegouwen
11:15 Room 1A Oral poster presentations
13:30 Welcome
12:30 Lunch break
13:40 Room 2 PLENARY LECTURE
M. Flickinger
Room 12 Room 11
Room 18 Room 13/14 Room 15/16 Room 17
14:00 R. Forster K. Bayer
Prokaryotic Genomics Biocatalysis Fermentation Natural Products
14:30 D. Vetter M. Hartmann Chair A. Pühler A. Liese E. Flaschel R. Frank
15:00 Coffee break 14:35 KEYNOTE G. Antranikian G. Steinhorn T.L.H. Pham
15:00 R. Müller M. Struhalla P.-J. Lin J. Imhoff
15:25 A. Schlüter N. Weizenmann M. Rhiel F. de la Calle
15:30 Room 1A
15:50 Coffee break
Oral poster presentations
16:20 W. Wohlleben J. Schrader KEYNOTE R. Cox
16:45 K. Niehaus M. Martinez C. Wyman D. O‘Hagan
17:00 Networking 17:10 J. Kalinowski J. von Langermann T. Purkarthofer J. Pietruszka
17:35 M. Brocker KEYNOTE H. Schmidt A. Kirschning
18:00 M. Bott R. Kazlauskas S.N. Lindner M. Müller
18:30 Room 1A PLENARY LECTURE
S. Minger
Room 1A BIOTECHNICA GRADUATE AWARD
R. Balling
19:30 Hall 9 General Assembly
Social event 19:30 Poster Party
of DECHEMA Biotechnology
10 EUROPEAN BIOPERSPECTIVES 2008 EUROPEAN BIOPERSPECTIVES 2008 11WEDNESDAY, OCTOBER 8, 2008 PROGRAM AT A GLANCE PROGRAM AT A GLANCE WEDNESDAY, OCTOBER 8, 2008
Science to Market
organized by EAPB –
European Association of Pharma
Biotechnology 9:00 Room 2 PLENARY LECTURE
9:00 Room 1A J. Mattick
KEYNOTE
C. Baum Room 2 DECHEMA AWARDS CEREMONY
A. Oberholz
9:45 Coffee break Room 17 Room 18 Room 13/14 Room 15/16 Room 3A Room 3B Room Frankfurt
Bioinformatics / Eukaryotic Genomics Measuring & Control Downstream ChemBioTec German Platform White VBU BioBusiness
Metabolome Analysis Processing Biotechnology Forum*
Room 11 Room 12 Chair D. Schomburg H. Blöcker T. Scheper R. Ulber F. Eiden B. Garthoff U. Behrendt
10:00 P. Maurer E. Martinez Fraiz 10:00 J. Spura K. Stangier V. Schünemann L. Villain H. Zorn A. Oberholz M. Partl
10:30 G. Borchard K. Maynard 10:25 T. Koal C. Maercker T. Becker N. Tippkötter B. Geueke P. Lange G. Lustyik
10:50 Coffee Break
11:00 Room 1A 11:15 S.R. Talbot F. Weise E. Heinzle KEYNOTE T. Eggert C. Wandrey P. Grigorjev
Oral poster presentations
11:40 M. Sultan A. Vester R. DiCosimo U. Bornscheuer H. Zinke T. Twardowski
KEYNOTE
12:05 O. Kohlbacher A. Pscherer A. Glindkamp L. Eggeling F. Giffhorn M. Schnee V. Eryomin
12:15 Room 1A Panel discussion
12:30 Lunch break
12:45 Networking / Lunch break
14:00 Room 2 PLENARY LECTURE
W. Weber
Room 11 Room 17 Room 18 Room 13/14 Room 15/16 Room 3A Room 3B Room Frankfurt
REBIRTH* Bioinformatics / Proteomics Measuring & Control Downstream ChemBioTec German Platform White VBU BioBusiness
Metabolome Analysis Processing Biotechnology Forum*
Chairs A. Haverich / U. Martin Chair O. Kohlbacher F. Lottspeich E. Heinzle C. Wandrey U. Bornscheuer D. Sell C. Lang
14:55 U. Martin 14:55 A. Torda KEYNOTE R. Luttmann E.M. del Amor Villa P. Fröhlich J. Ryan
Highlights 2021-
B. Lange Clusters
15:20 J. Borstlap 15:20 M. Rarey C. Buckl M. Mirata B. Bühler L. Vingiani
15:45 J.M. Braun 15:45 I. Koch A. Brunner A. Bluma J. Arfsten L. Greiner V. Sieber W. Skibar
16:10 Coffee break 16:10 Coffee break
16:40 K. Kratz 16:40 G. Poschmann A.-P. Zeng S. Billig G. Schembecker T. Hirth, C. Syldatk, B. Gilarranz
KEYNOTE
B. Gilleßen,
16:55 C. Kasper 17:05 C. Proctor H. Göhler S. Steigmiller K. Ralla A. Spieß C. Schulze Gronover
17:10 K. Boztug 17:15
General Assembly of the
18:30 German Association of
BIOTECHNICA Night Biotechnology
Companies (VBU)
* organized by Hannover Medical School (MHH) * attendance of VBU BioBusiness Forum is free of charge/organized by VBU – Association of German Biotechnology Companies
12 EUROPEAN BIOPERSPECTIVES 2008 EUROPEAN BIOPERSPECTIVES 2008 13THURSDAY, OCTOBER 9, 2008 PROGRAM AT A GLANCE PROGRAM AT A GLANCE THURSDAY, OCTOBER 9, 2008
9:00 Room 2 PLENARY LECTURE
R. Aebersold
Room 3A Room 13/14 Room 17 Room 15/16 Room 18
Protein Engineering Systems Biology Cell Culture Technology/ Medical Renewables DBU Fellowship
Applications Session
Chair A. Pingoud B. Junker R. Pörtner R. Ulber A. Liese
9:55 KEYNOTE T. Fürch KEYNOTE R. Hausmann T. Fischer
10:20 F. Buchholz A. Kremling J. Itskovitz-Eldor M. Rarbach J. Rehdorf
10:45 Coffee break
11:15 M. Schlapschy S. Noack M. Mehtali KEYNOTE K. Ullrich
11:40 B. Stosik P. Götz S. Mayfield J. Rühl
KEYNOTE
12:05 S. Dorscheid L. Wiehlmann F.M. Wurm P. Welters N. Luniak
12:30 Lunch break
14:00 Room 2 PLENARY LECTURE
J. Chin
Room 3A Room 13/14 Room 17 Room 15/16 Room 18
Protein Engineering Synthetic Biology Cell Culture Technology/ Medical Renewables ChemBioTech
Applications
Chair A. Skerra W. Weber H. Hauser C. Syldatk A. Schmid
14:55 KEYNOTE T. May A. Rath V. Lürbke U. Kragl
15:20 D. Hilvert B. Wiltschi R. Pörtner D. Ihrig S. Bräutigam
15:45 P. Kornberger M. Tigges D. Wirth O. Pulz M. Berheide
16:10 Coffee break
16:30 C. Lange A. Tauch T. Cantz H. Dörnenburg M. Bureik
16:55 V. Urlacher C. Cavelier V. Georgiev A. Neumann
17:20 End of conference
14 EUROPEAN BIOPERSPECTIVES 2008 EUROPEAN BIOPERSPECTIVES 2008 15PLENARY LECTURES KEYNOTE LECTURES
Tuesday, October 7, 2008 13:30 ■
KEYNOTE L ECTURES ■■
WELCOME Tuesday, October 7, 2008
Prof. Thomas Scheper Myxobacterial functional genomics for the 14:35
University of Hannover/D production of bioactive natural products
Prof. Rolf Müller, Saarland University, Saarbrücken/D
■
P LEN ARY L E CT U R E S ■■
Tuesday, October 7, 2008 Biological production of sustainable transportation 16:20
fuels from plants: progress, challenges and opportunities
Microbial biocatalysis in nanostructured adhesive coatings 13:40
Dr. Charles E. Wyman, University of California, Riverside, CA/USA
Prof. Michael C. Flickinger, North Carolina State University,
Raleigh, NC/USA
Teaching enzymes to catalyze new reactions 17:35
Therapeutic and research potential of human stem cells: 18:30 Prof. Romas Kazlauskas, University of Minnesota,
prospects and challenges St. Paul, MN/USA
Dr. Stephen Minger, King‘s College London/UK
Wednesday, October 8, 2008 Wednesday, October 8, 2008
The human genome as an RNA machine 9:00 Enzymatic production of peracetic acid 11:15
Prof. John Mattick, The University of Queensland, Brisbane/AUS Dr. Robert DiCosimo, Du Pont Company, Wilmington, DE/USA
Synthetic biology in mammalian cells – novel perspectives for drug
discovery and bioengineering Computational proteomics – making sense of gigabytes 11:40
Dr. Wilfried Weber, ETH Zurich/CH Prof. Oliver Kohlbacher, University of Tübingen/D
Thursday, October 9, 2008 A molecular interaction network characterising composition 14:55
Quantitative proteomics and systems biology 9:00 and protein complex function in cell division pathways
Prof. Rudolf Aebersold, ETH Zurich and University of Zurich/CH and PD Dr. Bodo Lange, Max Planck Institute for Molecular Genetics,
Institute for Systems Biology, Seattle, WA/USA Berlin/D
Molecular mechanisms of ageing – an in silico approach 16:40
Ribosome engineering and new genetic codes 14:00 C.J. Proctor, University of Newcastle/UK
Dr. Jason W. Chin, MRC Laboratory of Molecular Biology,
Cambridge/UK
16 EUROPEAN BIOPERSPECTIVES 2008 EUROPEAN BIOPERSPECTIVES 2008 17KEYNOTE LECTURES REVIEW BIOPERSPECTIVES 2007
■
K EY N O T E L E CT U R E S ■■
Thursday, October 9, 2008
Development of site-specific recombinases for genome surgery 9:55
Dr. Frank Buchholz, Max Planck Institute of Molecular Cell Biology
and Genetics, Dresden/D
Production and expansion of human embryonic stem cells 9:55
for clinical and industrial applications
Prof. Joseph Itskovitz-Eldor, Technion – Israel Institute of Technology,
Haifa/IL
Micro-algae as a platform for the production of therapeutic 11:15
proteins and biofuels
Dr. Stephen P. Mayfield, The Scripps Research Institute,
La Jolla, CA/USA
25 years of cell culture based manufacturing for a 11:40
multi-billion $ market with recombinant biopharmaceuticals –
from gene to process
Prof. Florian M. Wurm, Swiss Federal Institute of Technology,
Lausanne/CH and ExcellGene SA, Monthey/CH
Teaching old enzymes new tricks 14:55
Prof. Donald Hilvert, ETH Zurich/CH
18 EUROPEAN BIOPERSPECTIVES 2008 EUROPEAN BIOPERSPECTIVES 2008 19TUESDAY, OCTOBER 7 – AFTERNOON PROGRAM PROGRAM AFTERNOON – TUESDAY, OCTOBER 7
13:30 Room 2 WELCOME Room 2 WELCOME 13:30
13:40 Room 2 PLENARY LECTURE Room 2 PLENARY LECTURE 13:40
Microbial biocatalysis in nanostructured adhesive coatings Microbial biocatalysis in nanostructured adhesive coatings
M.C. Flickinger, North Carolina State University, Raleigh, NC/USA M.C. Flickinger, North Carolina State University, Raleigh, NC/USA
Room 18 Room 13/14 Room 15/16 Room 17
Prokaryotic Genomics Biocatalysis Fermentation Natural Products
Chair A. Pühler A. Liese E. Flaschel R. Frank
14:35 KEYNOTE LECTURE Extremophiles as a source of enzymes for The continuously operated shaken bioreactor Investigation of secondary metabolites from 14:35
industrial application system COSBIOS as a novel tool for testing microorganisms by using a combination of
Myxobacterial functional genomics for the
G. Antranikian, Hamburg University of Technology plasmid stability on-line and off-line chromatographic and
production of bioactive natural products
(TUHH)/D G. Steinhorn, RWTH Aachen University/D; C. Müller, spectroscopic methods
R. Müller, Saarland University, Saarbrücken/D
m2p-labs GmbH, Aachen/D; J. Weber, T.L.H. Pham, TU Berlin/D; I. Zaspel, D. Ewald,
TU Dresden/D; T. Anderlei, Kühner AG, Basel/CH; Federal Research Institute for Rural Areas, Forestry
J. Büchs, RWTH Aachen University/D and Fisheries, Waldsieversdorf/D; C. Mügge,
Humboldt Universität Berlin/D; E. Krause, Leibniz
Institute for Molecular Pharmacology, Berlin/D
15:00 A new mutagenesis method for the engineering Effect of agitation and aeration on pelleted mor- Marine biotechnology: bio-mining the treasures 15:00
of enzymes for biocatalysis phology and product formation of Aspergillus of the ocean
M. Struhalla, c-LEcta GmbH, Leipzig/D niger J.F. Imhoff, A. Labes, I. Kajahn, M. Krämer, R. Stöhr,
P.-J. Lin, T. Hagemann, A. Stintzing, C. Appel, D.C. V. Thiel, J. Wiese, Kieler Wirkstoffzentrum am
Hempel, R. Krull, TU Braunschweig/D IFM-GEOMAR/D
15:25 Insight into the metagenome of a biogas plant Side-directed mutagenesis of the amylomaltase First-time-right process development with a From marine biodiversity to innovative drugs. 15:25
microbial community from Thermus aquaticus ATCC 33923 fully automated 32 bioreactor system operated The experience of PharmaMar
A. Schlüter, A. Goesmann, Bielefeld University/D; N. Weizenmann, C. Roth, N. Straeter, W. Zimmer- as scale-down model of the final production F. de la Calle, PharmaMar S.A., Madrid/ES
L. Krause, Nestle Research Center, Lausanne/CH; mann, University of Leipzig/D bioreactors
R. Szczepanowski, A. Pühler, Bielefeld University/D M. Rhiel, R. Faller, L. Hostettler, J. Sieck, T. Grün,
C. Leist, Novartis Pharma AG, Basel/CH
15:50 Coffee break Coffee break 15:50
20 EUROPEAN BIOPERSPECTIVES 2008 EUROPEAN BIOPERSPECTIVES 2008 21TUESDAY, OCTOBER 7 – AFTERNOON PROGRAM PROGRAM AFTERNOON – TUESDAY, OCTOBER 7
Room 18 Room 13/14 Room 15/16 Room 17
Prokaryotic Genomics Biocatalysis Fermentation Natural Products
Chair A. Pühler A. Liese E. Flaschel R. Frank
16:20 Antibiotic biosynthesis: from the DNA sequence Novel application and improved production of KEYNOTE LECTURE Fungal polyketide synthase – non-ribosomal 16:20
to the product chloroperoxidase from Caldariomyces fumago peptide synthetases: programmed
Biological production of sustainable transpor-
W. Wohlleben, E. Stegmann, T. Weber, B.-A. Kaup, K. Ehrich, M. Pescheck, M. Buchhaupt, nanomachines
tation fuels from plants: progress, challenges
University of Tübingen/D D. Holtmann, J. Schrader, DECHEMA e.V., Frankfurt R. Cox, University of Bristol/UK
and opportunities
am Main/D
C.E. Wyman, University of California, Riverside,
CA/USA
16:45 Functional genomics of the xanthan-producing Valorization of isosorbide. Optimal biosynthesis S-Adenosyl-L-methionine hydroxide: 16:45
phytopathogen Xanthomonas campestris pv. of mono ricinoleyl ester adenosyl transferase, the Duf-62 gene product
campestris M. Martínez, N. El Boulifi, J. Aracil, has biochemical and chemical similarity to the
K. Niehaus, Bielefeld University/D Compluentse University, Madrid/E fluorinase
D. O‘Hagan, H. Deng, University of St. Andrews/UK
17:10 The transcriptional regulatory network cont- Total suppression of the non-enzymatic reaction Fine-tuning of protein expression – Pichia Chemoenzymatic synthesis of marine oxylipins 17:10
rolling sulfur metabolism in Corynebacterium in hydroxynitrile lyase catalysed cyanohydrin pastoris AOX1-promoter library J. Pietruszka, M. Bischop, T. Fischer,
glutamicum synthesis F.S. Hartner, C. Ruth, Graz University of A.C.M. Rieche, D. Sandkuhl, Universität Düsseldorf
C. Rückert, A. Albersmeier, J. Milse, A. Lömker, J. von Langermann, U. Kragl, University of Technology/A; R. Weis, T. Purkarthofer, im Forschungszentrum Jülich/D
D. Koch, D. Rey, A. Pühler, J. Kalinowski, Bielefeld Rostock/D VTU Technology GmbH, Graz/A;
University/D A. Glieder, Graz University of Technology/A
17:35 The response regulator MtrA of C. glutamicum: KEYNOTE LECTURE Expression profiling and rational optimization of Ansamitocin compound libraries by 17:35
target genes, consensus binding site and influ- a prokaryotic host-/vector-expression system mutasynthesis
ence of phosphorylation Teaching enzymes to catalyze new reactions H. Schmidt, R. Schmuck, Roche Diagnostics K. Harmrolfs, F. Taft, M. Brünjes, A. Meyer,
M. Brocker, M. Bott, Research Centre Jülich R. Kazlauskas, University of Minnesota, St. Paul, GmbH, Penzberg/D; G. Unden, University of T. Frenzel, A. Kirschning, University of Hannover/D
GmbH/D MN/USA Mainz/D; H. Düfel, Roche Diagnostics GmbH,
Penzberg/D
18:00 Phosphorylation of the 2-oxoglutarate dehyd- Engineering of a glycerol utilization Natural products as a source of ‚new‘ building 18:00
rogenase inhibitor protein OdhI in Corynebac- pathway for amino acid production by blocks
terium glutamicum by multiple Ser/Thr protein Corynebacterium glutamicum M. Müller, University of Freiburg/D
kinases D. Rittmann, Research Centre Jülich GmbH/D;
C. Schultz, M. Bott, Research Centre Jülich S.N. Lindner, V.F. Wendisch, University of Münster/D
GmbH/D
18:30 Room 2 PLENARY LECTURE Room 2 PLENARY LECTURE 18:30
Therapeutic and research potential of human stem cells Therapeutic and research potential of human stem cells
S. Minger, King‘s College London/UK S. Minger, King‘s College London/UK
Room 2 BIOTECHNICA GRADUATE AWARD Room 2 BIOTECHNICA GRADUATE AWARD
R. Balling, President of VBIO R. Balling, President of VBIO
19:30 Hall 9 Poster party Hall 9 Poster party General Assembly of DECHEMA Biotechnology 19:30
22 EUROPEAN BIOPERSPECTIVES 2008 EUROPEAN BIOPERSPECTIVES 2008 23WEDNESDAY, OCTOBER 8 – MORNING PROGRAM PROGRAM MORNING – WEDNESDAY, OCTOBER 8
09:00 Room 2 PLENARY LECTURE* Room 2 PLENARY LECTURE* 09:00
The human genome as an RNA machine The human genome as an RNA machine
J. Mattick, The University of Queensland, Brisbane/AUS J. Mattick, The University of Queensland, Brisbane/AUS
Room 2 DECHEMA AWARDS CEREMONY Room 2 DECHEMA AWARDS CEREMONY
A. Oberholz, Chairman of DECHEMA A. Oberholz, Chairman of DECHEMA
Room 17 Room 18 Room 13/14 Room 15/16
Bioinformatics / Metabolome Analysis Eukaryotic Genomics Measuring & Control Downstream Processing
Chair D. Schomburg H. Blöcker T. Scheper R. Ulber
10:00 Screening of transposon mutants of Coryne- Next-gen sequencing technologies: drawbacks Mössbauer spectroscopy: a tool for characteri- Virus retentive filtration of polyclonal immuno- 10:00
bacterium glutamicum using a high-throughput and opportunities zation of iron depending enzymatic reactions globulins: dominant filtration mechanisms and
method for microbial metabolome analysis K. Stangier, GATC Biotech AG, Konstanz/D V. Schünemann, K. Muffler, R. Ulber, strategies to prevent fouling
J. Spura, L. Reimer, T. Lühr, D. Schomburg, TU Kaiserslautern/D L. Villain, University of Hannover/D; I. Masselin,
TU Braunschweig/D V. Thom, Sartorius-Stedim Biotech GmbH,
Göttingen/D; T. Scheper, University of Hannover/D
10:25 Targeted metabolomics – simultaneous and A new assay in functional genomics: monitoring Ultrasonic based sensor array for the simul- An automated pilot plant for the bioengineering 10:25
quantitative LC/MS/MS analysis of energy me- of cell differentiation in live cell chips by electric taneous analysis of sugar and ethanol for the processing of concentrated whey
tabolism and prostaglandine intermediates and cell-substrate impedance sensing bioethanol production N. Tippkötter, W. Roikaew, R. Ulber, University of
cholesterol derivatives in biological samples C. Maercker, Mannheim University of Applied T. Becker, T. Schöck, University of Hohenheim, Kaiserslautern/D
T. Koal, D. Kirchberg, P. Enoh, I. Unterwurzacher, Sciences/D; D. Breitkreutz, German Cancer Stuttgart/D
C. Röhring, H.-P. Deigner, S. Dammeier, M. Keller, Research Center (DKFZ), Heidelberg/D; A. Bieser,
K. Weinberger, BIOCRATES Life sciences AG, ibidi GmbH, Martinsried/D; K. Bieback, University of
Innsbruck/A Heidelberg, Mannheim/D; M. Angstmann,
Mannheim University of Applied Sciences/D
10:50 Coffee break Coffee break 10:50
11:15 Identification of potential bacterial biological High-throughput screening of an shRNA library Parallel optical online measurement of DO and KEYNOTE LECTURE 11:15
warfare agents with spectroscopic methods generated by enzymatic engineering of cDNA pH during cultivation in shake flasks
Enzymatic production of peracetic acid
using multivariate statistics from human pancreatic tumour tissue K. Schneider, V. Schütz, E. Heinzle, Saarland
R. DiCosimo, Du Pont Company, Wilmington,
S.R. Talbot, H. Russmann, Bundeswehr Institute M. Thomas, A. Oehmig, F. Weise, H. Volkmer, University, Saarbrücken/D; G.T. John, C. Krause,
DE/USA
for Protective Technologies and NBC Protection, Natural and Medical Sciences Institute at the Presens GmbH, Regensburg/D
Munster/D; T. Scheper, University of Hannover/D University of Tübingen, Reutlingen/D
11:40 KEYNOTE LECTURE EURExpress, a web-based gene expression Automated high-throughput fermentation pro- 11:40
atlas of the developing mouse embryo cess optimization
Computational proteomics – making sense of
M. Sultan, Max Planck Institute for Molecular A. Vester, TU München, Garching/D; M. Hans,
gigabytes
Genetics, Berlin/D H.-P. Hohmann, L. Tijhuis, DSM Nutritional
O. Kohlbacher, University of Tübingen/D
Products AG, Kaiseraugst/CH; D. Weuster-Botz,
TU München, Garching/D
12:05 Functional oncogenomics in mantle cell lympho- Ratiometric optical sensing of temperature and Relevance of export for bacterial metabolite 12:05
ma: a model cell system for complex diseases oxygen based on luminescence quenching production
A. Pscherer, A. Farfsing, D. Magalei, S. Ohl, A. Glindkamp, M. Fritzsche, University of L. Eggeling, R. Diesveld, Research Centre Juelich/D
F. Engel, M. Schnoelzer, German Cancer Research Hannover/D; R. Baumfalk, Sartorius AG,
Center (DKFZ), Heidelberg/D; C. Schwaenen, Göttingen/D; S. Beutel, T. Scheper, University of
H. Döhner, S. Stilgenbauer, Medical School Ulm/D; Hannover/D
P. Lichter, German Cancer Research Center (DKFZ),
Heidelberg/D
12:30 Hall 9 Lunch break Hall 9 Lunch break 12:30
* Plenary Lecture kindly supported by Qiagen
24 EUROPEAN BIOPERSPECTIVES 2008 EUROPEAN BIOPERSPECTIVES 2008 25WEDNESDAY, OCTOBER 8 – MORNING PROGRAM PROGRAM MORNING – WEDNESDAY, OCTOBER 8
09:00 Room 2 PLENARY LECTURE* Room 2 PLENARY LECTURE* 09:00
The human genome as an RNA machine The human genome as an RNA machine
J. Mattick, The University of Queensland, Brisbane/AUS J. Mattick, The University of Queensland, Brisbane/AUS
Room 2 DECHEMA AWARDS CEREMONY Room 2 DECHEMA AWARDS CEREMONY
A. Oberholz, Chairman of DECHEMA A. Oberholz, Chairman of DECHEMA
Room 3A Room 3B Room Frankfurt
ChemBioTec German Platform White Biotechnology VBU BioBusiness Forum**
Europe’s Biotech Markets: Facts & Figures
Chair F. Eiden B. Garthoff U. Behrendt Chair
10:00 Fungal secretomes – versatile toolbox for white White Biotechnology – at the eve of a Biotechnology in the Czech Republic
biotechnology revolution M. Partl, CzechInvest - Investment and Business 10:00
H. Zorn, I. Schüttmann, H. Bouws, TU Dortmund/D A. Oberholz, Evonik Industries AG, Essen/D Development Agency, Prague/CZ
10:25 Enzyme-catalyzed synthesis of beta-peptides White biotechnology – the BMBF perspective Biotechnology in Hungary
T. Heck, H.P.E. Kohler, B. Geueke, Eawag, P. Lange, BMBF, Berlin/D G. Lustyik, Soft Flow Hungary Ltd, Hungarian 10:25
Dübendorf/CH Biotechnology Association, Pécs/HU
10:50 Coffee break Coffee break
10:50
st
11:15 Enantioselective biosynthesis of hydroxyketones White Biotechnology in the 21 century Biotechnology in the Baltic States
catalyzed by novel glycerol dehydrogenases C. Wandrey, Research Centre Jülich GmbH/D P. Grigorjev, Estonian Biotechnology Association, 11:15
T. Eggert, N. Richter, evocatal GmbH, Düsseldorf/D; Tallin/EST
W. Hummel, University of Düsseldorf; A. Liese,
M. Neumann, Hamburg University of Technology
(TUHH); R. Wohlgemuth, Sigma-Aldrich Chemie
GmbH, Buchs/CH
11:40 Laccases for the synthesis of fine chemicals Contribution of SME to the white biotech Biotechnology in Poland 11:40
U. Bornscheuer, M. Schmidt, L. Hilterhaus, industrial transformation process T. Twardowski, Polish Federation of Biotechnology,
S. Herter, A. Mikolasch, F. Schauer, Greifswald H. Zinke, BRAIN AG, Zwingenberg/D Poznań /PL
University/D; K. Liebeton, J. Eck, BRAIN AG,
Zwingenberg/D; R. Wohlgemuth, Sigma Aldrich
Chemie GmbH, Buchs/CH; S. Illner, D. Hameister,
U. Kragl, Rostock University/D
12:05 Sustainable and efficient sythesis of rare phar- White Biotechnology at the capital market Biotechnology in Russia 12:05
maceutical sugars based on biocatalysis with M.J. Schnee, Schnee Research, Maintal/D; V. Eryomin, Bakh Institute of Biochemistry of the
engineered enzymes and reaction engineering T. Heine, DIB, Frankfurt am Main/D RAS, Moscow/RUS (to be confirmed)
S. Dorscheid, B. Stosik, M. Pitz, K. Schneider,
G. Kohring, E. Heinzle, F. Giffhorn, Saarland
University, Saarbrücken/D
12:30 Hall 9 Lunch break Hall 9 Lunch break 12:30
* Plenary Lecture kindly supported by Qiagen ** attendance of VBU BioBusiness Forum is free of charge / organized by VBU - Association of German Biotechnology
Companies
26 EUROPEAN BIOPERSPECTIVES 2008 EUROPEAN BIOPERSPECTIVES 2008 27WEDNESDAY, OCTOBER 8 – AFTERNOON PROGRAM PROGRAM AFTERNOON – WEDNESDAY, OCTOBER 8
14:00 Room 2 Room 2 14:00
PLENARY LECTURE PLENARY LECTURE
Synthetic biology in mammalian cells – novel perspectives Synthetic biology in mammalian cells – novel perspectives
for drug discovery and bioengineering for drug discovery and bioengineering
W. Weber, ETH Zurich/CH W. Weber, ETH Zurich/CH
Room 17 Room 18 Room 13/14 Room 15/16
Bioinformatics / Proteomics Measuring & Control Downstream Processing
Metabolome Analysis
Chair O. Kohlbacher F. Lottspeich E. Heinzle C. Wandrey Chair
14:55 RNA: design, structure and why we do not like KEYNOTE LECTURE Applications of mathematical modeling in moni- Development of an integrated process for 14:55
computer scientists toring and control of bioreaction processes the production and isolation of invertase from
A molecular interaction network characterising
A. Torda, University of Hamburg/D R. Luttmann, E. Hukelmann, K. Lögering, M. Poppe, Saccharomyces cerevisiae
composition and protein complex function in
J. Flothmann, J. Fricke, J. Hülsmann, C. Nowacki, E.M. del Amor Villa, R. Wichmann,
cell division pathways
Hamburg University of Applied Sciences/D TU Dortmund/D
M.-L. Fogeron, H. Müller, K. Habermann,
V. Lehmann, T. Kurtz, A.-K. Scholz, A. Haupt,
15:20 Index-driven structure-based virtual screening Sensor networks Integrated bioprocess for the production of the 15:20
H. Lehrach, Max Planck Institute for Molecular Gene-
M. Rarey, J. Schlosser, University of Hamburg/D C. Buckl, A. Knoll, TU München, Garching/D natural antimicrobial monoterpene R-(+)-perillic
tics, Berlin/D; S. Steinbrink, German Cancer
acid with P. putida
Research Center (DKFZ), Heidelberg/D; J. Gobom,
M. Mirata, J. Schrader, DECHEMA e.V., Frankfurt/D
Max Planck Institute for Molecular Genetics, Berlin/D;
M. Boutros, German Cancer Research Center
(DKFZ), Heidelberg/D; B.M.H. Lange, Max Planck
Institute for Molecular Genetics, Berlin/D
15:45 Petri nets analysis techniques for modeling How to find significantly regulated proteins in Inline monitoring of crystallization processes Correlation of the micromechanical properties 15:45
metabolic networks isotope-labeling based proteomics with in-situ microscopy of S. cerevisiae with the cell disintegration
I. Koch, Technical University of Applied Sciences, A. Brunner, Max Planck Institute of Biochemistry, A. Bluma, T. Höpfner, P. Lindner, G. Rudolph, behavior
Berlin/D Martinsried/D S. Beutel, B. Hitzmann, University of Hannover/D; J. Arfsten, I. Kampen, A. Kwade,
G. Martinez, Universidad de Costa Rica, TU Braunschweig/D
San Jose/CR; T. Scheper, University of Hannover/D
16:10 Coffee break Coffee break 16:10
16:40 KEYNOTE LECTURE Tissue-based proteome analysis: the first stage Modelling and control of cell culture: from a Purification and characterization of a carboxyl 16:40
in the biomarker discovery pipeline black-box to systems biology esterase from Thermobifida fusca KW3
Molecular mechanisms of ageing – an in silico
G. Poschmann, B. Sitek, University of Bochum/D; A.-P. Zeng, Hamburg University of Technology degrading poly(ethylene terephthalate) trimers
approach
B. Sipos, G. Klöppel, University of Kiel/D; (TUHH)/D S. Billig, W. Zimmermann, University of Leipzig/D
C.J. Proctor, R.J. Boys, C.S. Gillespie, C. Lawless,
F. Ramaekers, University of Maastricht/NL;
D.P. Shanley, D.J. Wilkinson, T.B.L. Kirkwood,
H.E. Meyer, K. Stühler, University of Bochum/D
University of Newcastle/UK*
17:05 Characterisation of the autoimmune antibody BaychroMAT bioplatform as a tool for quality by Adsorption and separation of proteins with 17:05
repertoire of Parkinson’s disease patients by design smectitic clay minerals
systematic screening of protein arrays M. Gerlach, S. Steigmiller, H. Tups, Bayer Technology K. Ralla, D. Riechers, University of Hannover/D;
H. Göhler, A. Kowald, University of Bochum/D; Services GmbH, Leverkusen/D U. Sohling, Süd-Chemie AG, Moosburg/D;
A. Lueking, C. Scheer, University of Würzburg/D; C. Kasper, T. Scheper, University of Hannover/D
M. Gerlach, K. Marcus, D. Woitalla, H.E. Meyer,
University of Bochum/D
18:30 Munich Hall BIOTECHNICA Night Munich Hall BIOTECHNICA Night 18:30
* Keynote lecture kindly supported by GBM
28 EUROPEAN BIOPERSPECTIVES 2008 EUROPEAN BIOPERSPECTIVES 2008 29WEDNESDAY, OCTOBER 8 – AFTERNOON PROGRAM PROGRAM AFTERNOON – WEDNESDAY, OCTOBER 8
14:00 Room 2 Room 2 14:00
PLENARY LECTURE PLENARY LECTURE
Synthetic biology in mammalian cells – novel perspectives Synthetic biology in mammalian cells – novel perspectives
for drug discovery and bioengineering for drug discovery and bioengineering
W. Weber, ETH Zurich/CH W. Weber, ETH Zurich/CH
Room 3A Room 3B Room Frankfurt Room 11
ChemBioTec German Platform White Biotechnology VBU BioBusiness Forum*
REBIRTH**
Europe’s Biotech Markets: Facts & Figures
Chair U. Bornscheuer D. Sell C. Lang A. Haverich / U. Martin Chair
14:55 Biocatalytic functionalisation of alkyl substituted Highlights from the BioIndustry 2021-Clusters 14:55 Biotechnology in Ireland Exzellence Cluster REBIRTH – „From 14:55
polysiloxanes R. Grote, Biokatalyse 2021 J. Ryan, CIRCA Group Europe Limited, Dublin/IRL Regenerative Biology to Reconstructive
P. Fröhlich, University of Freiberg/D; J. Stohrer, R. Kindervater, Biopolymers, Biomaterials Therapy“ and Stem cell research: induced
E. Fritz-Langhals, Wacker Chemie AG, Munich/D; M. Kircher, CLIB 2021 pluripotent stem cells (iPS cells)
P. Dünkelmann, Codexis AG, Jülich/D; M. Bertau, D. Terzenbach, Integrated Bioindustry U. Martin, Hannover Medical School (MHH)/D
University of Freiberg/D H. Zorbas, Cluster IBP
15:20 Using systems biotechnology and eco-efficiency 15:20 Biotechnology in Italy Regenerative Medicine Initiative Germany 15:20
analyses to enable sustainable redox L. Vingiani, Assobiotec, Milano/I (RMIG) and Berlin-Brandenburg Center for
biocatalysis Regenerative Therapies (BCRT)
B. Bühler, D. Kuhn, TU Dortmund/D; A. Kholiq, J. Borstlap, Berlin-Brandenburg Center for
E. Heinzle, Saarland University, Saarbrücken/D; Regenerative Therapies, Berlin/D
L.M. Blank, A. Schmid, TU Dortmund and ISAS-
Institute for Analytical Sciences, Dortmund/D
15:45 Ionic liquids in biocatalysis: technical White Biotech: from biomass to product 15:45 Biotechnology in UK Translational Centre for Regenerative Medicine 15:45
applications and general perspective V. Sieber, A. Koltermann, Süd-Chemie AG, W. Skibar, Bioscience for Business, Chester/UK (TRM Leipzig) and preclinical models for cell
L. Greiner, C. Kohlmann, P. Müller, Munich/D therapies
M. Eckstein, RWTH Aachen University/D; J.M. Braun, University of Leipzig/D
S. Na‘amnieh, X-Zyme GmbH, Düsseldorf/D;
S. Lütz, Research Centre Jülich GmbH/D
16:10 Coffee break Coffee break 16:10
16:40 Modeling and simulation of downstream New enzymes and processes for biobased 16:40 Biotechnology in Spain Degradation behavior of hydrolyzable 16:40
processes products via the integration of biotechnological B. Gilarranz, Genoma España, Madrid/ES biomaterials
P. Balling, M. Günther, INOSIM GmbH, and chemical methods (BioSysPro) K. Kratz, A. Lendlein, GKSS Research Centre,
Ammersbek/D; T. Hellenkamp, G. Schembecker, T. Hirth, Fraunhofer Institute for Interfacial Geesthacht/D
TU Dortmund/D; T. Schwarz, bitop AG, Witten/D Engineering and Biotechnology IGB, Stuttgart/D;
C. Sydatk, University of Karlsruhe/D; D. Prüfer, Large Scale Cultivation 16:55
17:05 Enzyme catalysed reactions using gaseous University of Münster/D; B. Gilleßen, RWTH Aachen C. Kasper, T. Scheper, University of Hannover/D
substrates University/D; C. Schulze Gronover, Fraunhofer
A.C. Spieß, K. Dimoula, K. Nagayama, R. Mikolajek, Institute for Molecular Biology and Applied Ecology, A novel immunodeficiency syndrome with 17:10
RWTH Aachen University/D Aachen/DUniversity/D 17:15 defects in hematopoietic stem cell differentiation
K. Boztug, A. Ashikov, G. Appaswamy,
General Assembly of the German Association A.A. Schäffer, U. Salzer, J. Diestelhorst,
of Biotechnology Companies (VBU) M. Germeshausen, G. Brandes, J. Lee-Gossler,
K. Welte, H. Bakker, R. Gerardy-Schahn, C. Klein;
Hannover Medical School/D
18:30 Munich Hall BIOTECHNICA Night Munich Hall BIOTECHNICA Night 18:30
* attendance to VBU BioBusiness Forum is free of charge / organized by VBU – Association of German Biotechnology
Companies
** organized by Hannover Medical School (MHH)
30 EUROPEAN BIOPERSPECTIVES 2008 EUROPEAN BIOPERSPECTIVES 2008 31THURSDAY, OCTOBER 9 – MORNING PROGRAM PROGRAM MORNING – THURSDAY, OCTOBER 9
09:00 Room 2 PLENARY LECTURE Room 2 PLENARY LECTURE 09:00
Quantitative proteomics and systems biology Quantitative proteomics and systems biology
R. Aebersold, ETH Zurich and University of Zurich/CH and Institute for Systems Biology, R. Aebersold, ETH Zurich and University of Zurich/CH and Institute for Systems Biology,
Seattle, WA/USA Seattle, WA/USA
Room 3A Room 13/14 Room 17 Room 15/16
Protein Engineering Systems Biology Cell Culture Technology / Medical Applications Renewables
Chair A. Pingoud B. Junker R. Pörtner R. Ulber Chair
9:55 KEYNOTE LECTURE A systems biotechnological approach to KEYNOTE LECTURE New approaches for the economical production 9:55
optimized recombinant protein production using of microbial rhamnolipids
Development of site-specific recombinases for Production and expansion of human embryonic
Bacillus megaterium R. Hausmann, F. Leitermann, V. Walter, C. Syldatk,
genome surgery stem cells for clinical and industrial applications
T. Fürch, W. Wang, C. Wittmann, E. Franco-Lara, University of Karlsruhe/D
F. Buchholz, Max Planck Institute of Molecular Cell M. Amit, J. Itskovitz-Eldor, Technion – Israel Institute
D. Jahn, D.C. Hempel, TU Braunschweig/D
Biology and Genetics, Dresden/D of Technology, Haifa/IL
10:20 Modeling bacterial carbohydrate uptake – from System approach to 2nd generation biofuels 10:20
the sensory system to the global transcriptional M. Rarbach, A. Koltermann, Süd-Chemie AG,
network Munich/D
A. Kremling, K. Bettenbrock, S. Kremling,
E.D. Gilles, Max Planck Institute Magdeburg/D
10:45 Coffee break Coffee break 10:45
11:15 Extending the plasma half-life of biopharma- Integrative modeling of the TCA-cycle of Application of embryonic stem cells for the KEYNOTE LECTURE 11:15
ceutical proteins via genetic fusion with C. glutamicum based on multi-omics data industrial manufacture of biologicals
Micro-algae as a platform for the production
homo-amino-acid polymer (HAP) sequences S. Noack, M. Oldiges, Research Centre Jülich M. Mehtali, Vivalis SA, Saint-Herblain/F
of therapeutic proteins and biofuels
M. Schlapschy, I. Theobald, K. Wachinger, GmbH/D; W. Wiechert, University of Siegen/D
S.P. Mayfield, The Scripps Research Institute,
A. Skerra, TU München, Freising/D
La Jolla, CA/USA
11:40 Dissection and the involvement of the P450 Identification of regulatory interactions in KEYNOTE LECTURE 11:40
(CYP) monooxygenase system in the microorganisms from metabolite dynamics
25 years of cell culture based manufacturing
1,5-anhydro-D-fructose pathway in P. Götz, University of Stuttgart/D; J. Maczek,
for a multi-billion $ market with recombinant
Sinorhizobium meliloti S. Junne, TU Berlin/D
biopharmaceuticals - from gene to process
B. Stosik, F. Giffhorn, Saarland University, F.M. Wurm, Swiss Federal Institute of Technology,
Saabrücken/D Lausanne/CH and ExcellGene SA, Monthey/CH
12:05 Structural modification of pyranose 2-oxidase Population structure of Plantdustrial – linking plant and industrial 12:05
towards higher solubility and catalytic Pseudomonas aeruginosa biotechnology
performance L. Wiehlmann, N. Cramer, Hannover Medical A. Müller, G. Jach, P. Welters, Phytowelt
S. Dorscheid, M. Pitz, F. Giffhorn, School/D; G. Wagner, Clondiag Chip Technologies, GreenTechnologies GmbH, Nettetal/D
Saarland University, Saarbrücken/D Jena/D; T. Köhler, Geneva University Hospital/CH;
G. Morales, Centro Nacional de Biotecnologia,
Madrid/E; B. Tümmler, Hannover Medical School/D
12:30 Hall 9 Lunch break Hall 9 Lunch break 12:30
32 EUROPEAN BIOPERSPECTIVES 2008 EUROPEAN BIOPERSPECTIVES 2008 33You can also read
