GERIATRICS NEWS - UND School of Medicine

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GERIATRICS NEWS - UND School of Medicine
GERIATRICS NEWS                                                                                                        Fall 2020                 Vol. 1, No. 1

LAUN C H O F
DAKOTA GERIATRICS
As you might have heard, UND’s Department of Geriatrics was
awarded a $3.75 million grant from HRSA to improve geriatrics
education and transform primary care programs into Age Friendly
Health Care. The grant is for a Geriatrics Workforce Enhancement           Interprofessional training in geriatrics assessment. Health
Program, one of 47 such programs across the nation. Dubbed Dakota          Ambassador Teams for Seniors (HATS) is an interprofessional
Geriatrics, this GWEP serves both North and South Dakota, two states       community service-learning experience for health profession students
with some of the highest rates of Alzheimer’s disease in the country.      to enhance their geriatrics knowledge through geriatric assessment
Both states also have a severe shortage of geriatricians with a gap of     with an older adult.
40 specialists in each state.
                                                                                                          What Matters
                                                                                                          Know and align care with each older adult’s specific
                                                                                                          health outcome goals and care preferences including,
                                                                                                          but not limited to, end-of-life care, and across settings
                                                                                                          of care

                                                                                                          Medication
                                                                                                          If medication is necessary, use age-friendly medication
                                                                                                          that does not interfere with What Matters to the older
                                                                                                          adult, Mobility, or Mentation across settings of care

                                                                                                          Mentation
                                                                                                          Prevent, identify, treat, and manage delirium across
                                                                                                          settings of care

                                                                                                          Mobility
Key projects supported by Dakota Geriatrics are:                                                          Ensure that each older adult moves safely every day to
                                                                                                          maintain function and do What Matters
Online curriculum. Gero-Champion online education is an
interprofessional, faculty-led geriatrics multi-level curriculum. The      Age–friendly health care. Age-Friendly Health Systems is an initiative
three-level certification will cover 72 ACGME competencies for             of The John A. Hartford Foundation and the Institute for Healthcare
geriatric medicine, including the first level focusing on the 26 AAMC      Improvement (IHI) whose goal is expanding the 4Ms Framework to
competencies for medical students. Upon completion of each level,          20% of U.S. medical practices by the end of 2020. The 4Ms
the learner will receive a digital badge certificate of completion.        Framework is an essential set of evidence-based practices
                                                                           addressing: What Matters, Medication, Mentation, and Mobility.
Social media for improving geriatrics knowledge. “Art and Aging”
                                                                           Dakota Geriatrics continues to work with a number of health systems
social media combines evidence-based geriatric journal articles with
                                                                           across the state, including Indian Health Service and rural critical
artwork to bring engagement and enhance geriatrics knowledge. In
                                                                           access clinics, in adopting the 4Ms Framework and becoming age-
collaboration with Nicole Derenne, professor in UND’s Department of
                                                                           friendly recognized health systems.
Art & Design, Dakota Geriatrics utilizes multiple social media platforms
such as Facebook, Instagram, and Twitter to ensure a broad reach of        Age–friendly conference. In our continuing efforts of disseminating
healthcare professionals and student trainees.                             age-friendly healthcare education, Dakota Geriatrics is partnering with
                                                                           the National Indian Council on Aging (NICOA), Center for Rural Health
Learning senior population health through gaming. The serious
                                                                           (CRH), and Quality Health Associates (QHA) to present our first annual
game being developed in partnership with Drs. Richard Van Eck
                                                                           conference on Age-Friendly Health Care in the Great Plains, March
(SMHS Education Resources) and Scott Brewster (Triad Interactive
                                                                           30-31, 2021. The two-day program will bring regional experts to
Media, New York) combines evidence-based geriatrics education to
                                                                           discuss the geriatric 4Ms in patient care specific for American Indian
vignette-guided pathways that allow learners to apply the concept of
                                                                           populations.
age-friendly care to older adult population panels to impact health
outcomes and healthcare costs. The healthcare trainees will                Dementia education. ADRD training is a crucial component of the
understand geriatric care's additive impact above and beyond               Dakota Geriatrics program, and includes multiple ongoing projects.
"business as usual practices" by utilizing the geriatric 4Ms: What         One project is the annual “Dementia Friendly Healthcare and
Matters, Medication, Mentation, and Mobility during older adult care.                                                        ...continued on next page
GERIATRICS NEWS - UND School of Medicine
LAUNCH OF
                  DAKOTA GERIATRICS                                               Continued

Community” symposium. This group’s second meeting is
scheduled for June 21, 2021. In collaboration with the
Saint Louis Geriatric Gateway’s Geriatric Education Center
and the Wyoming Center on Aging, we will host national
                                                                        IMPACT
                                                                        We are happy and excited to report that in its inaugural year, Dakota
experts on dementia care for sessions directed towards
                                                                        Geriatrics built partnerships with multiple academic programs, health
providers, healthcare professionals, and community
                                                                        systems and community organizations across North and South Dakota.
workers. A second aspect of ADRD education is the
                                                                        Education efforts with academic partnerships reached 1801 students
development of a caregiver curriculum. In partnership with
                                                                        from different health care professions, including MD programs, nursing
the Alzheimer’s Association - ND/MN chapter, we are
                                                                        programs, physical therapy students, Pharm D students, residents from
developing a curriculum for caregivers of dementia
                                                                        internal medicine and family medicine programs, geriatric medicine
patients based on HRSA training modules. This curriculum
                                                                        fellows, multidisciplinary undergraduate students, and research fellows.
will be provided to clinics and health systems across the
                                                                        Including students, Year 1 training efforts reported engagement of
region for group visits and patient education. Additionally,
                                                                        14,073 trainees across North and South Dakota for various activities.
Dakota Geriatrics is a contributor to the Alzheimer’s State
                                                                        These involved training sessions, conferences, presentations, lectures,
Plan coalition where we will be providing educational and
                                                                        and other activities organized by Dakota Geriatrics and partners, and
survey content to create the ND Alzheimer’s State Plan.
                                                                        covered a host of trainees from various disciplines:
And last but not the least, there is an active effort in pursuit
to build partnerships between community organizations                                 Student Trainees                           1801
and health systems in order to include ADRD consults in                               Social Workers                               492
EHR for caregiver education for dementia patients.                                    Family Caregivers                            322
                                                                                      Older Adults                               1345
For   further   information     check     out   the    website
                                                                                      Nursing Professionals                        481
www.Dakotageriatrics.com
                                                                                      Faculty and Providers                        349
                                                                                      Community Members                          9632

EDUC AT IO N A L P R O G R A M S F O R
MEDICAL STUDENTS                                                              UNDERGRADUATES
MedSTAR program                                                                Abby Lake is one of two undergraduate students assisting in the
UND Geriatrics, in collaboration with the University of Nebraska,              Department. She comes from Faribault, Minn., and is currently a
launched the summer program for medical students to conduct                    freshman at the University of North Dakota majoring in biology with a
geriatrics research. Four rising second-year medical students                  pre-med emphasis. She really loves to play softball and was, in fact,
inaugurated the program, pursuing various medical education                    a two-time all-state athlete for her high school's softball team. She is
projects. Students received didactic presentations on biostatistics and        currently in her last year of eligibility for her club team.
geriatric principles of care. After the program, students gather their
                                                                               Ethlyn Voorhies is a French and molecular biology major who is also
data and will submit abstracts to the Annual American Geriatrics
                                                                               pre-medicine. She is a senior this year and is hoping to go to medical
Society meeting.
                                                                               school within the next two years. She has lived in Grand Forks for the
Geriatric Special Interest Group                                               past four years and has a two-year-old Aussie-doodle.
A group of second-year students reactivated the Geriatrics Special
Interest Group. One of the original plans was to have a “Geriatrics Fair”
in which participants learn about late life disabilities through mock
experiences that replicate visual, hearing, and physical impairments.
The pandemic put a crimp in that event, and students are organizing
virtual sessions as well as helping with the geriatrics telehealth program.
GERIATRICS NEWS - UND School of Medicine
UND G ER IAT RI C S AWA R D E D
$400,000 AHRQ SUBCONTRACT
UND Geriatrics was recently awarded a $400,000 AHRQ subcontract             to detail is so important, given that 25% of all COVID-19 deaths in the
to help deliver curriculum to regional nursing homes on ways to fight       U.S. are linked to nursing home staff and residents. Nearly 60,000
COVID-19. This project is support by the Institute for Healthcare           nursing home residents have died thus far.
Improvement and the National Education for Community Health
                                                                            UND Geriatrics has assembled a strong group of mentors for the
Outreach (ECHO). Currently, 7,000 of 15,000 nursing homes across
                                                                            ECHO CAN program. The faculty include two Geriatricians (Drs. Dahl
the country are enrolled in what is called ECHO COVID Action Network
                                                                            and Jurivich), two quality improvement experts (Drs. Marx and
ECHO CAN). The idea of the network is to provide a series of 16
                                                                            Lauckner) and two infectious disease experts (Drs. Janson and Salzer).
weekly training sessions focused on infection control and quality
                                                                            Also helping the team is staff from the North Dakota Long Term Care
improvement for nursing home, which will train a team of up to four
                                                                            Association. The overall intent is to standardize quality improvement
members (such as the Director of Nursing, Infection Control, Medical
                                                                            to be better able to prevent and manage the pandemic as well as
Director, and other representatives). The goal is to ramp up quality
                                                                            future infections. Rounding off the training program are sessions
improvement through Plan Do Study Act cycles of change. For
                                                                            devoted to wellness, social isolation, and burn out–all factors that can
instance, one quality improvement study found that nursing home staff
                                                                            contribute to lapses in infection control. If you are interested in these
incorrectly took off their gloves 50% of the time after handling infected
                                                                            presentations, ECHO sessions are recorded and posted on the Dakota
patients. This is why constant surveillance of how we do routine things
                                                                            Geriatrics website: dakotageriatrics.org.
is an important element of quality and infection control. This attention

NEW FA C U LT Y
AND STAFF
As one might imagine, a new Department is one of growth; so it comes                                 Bailey Knopf also joined the Department in
as no surprise that new faculty and staff joined the program this year.                              June as a research technician for the
With great excitement, the Department on–boarded Ram Mathur,                                         geriatrics laboratory. She graduated from the
Ph.D., as a research scholar and tenure track faculty member. Dr.                                    University of Iowa, and after having visited
Mathur is an emerging immunologist who is interested in how aging                                    Grand Forks with her family decided to make
impacts gut immunity, gut inflammation, and colon cancer. Dr. Mathur                                 the move north! Her research is focused on
has a Crohns Foundation grant and quickly engaged research                                           the aging stress response and she is looking
education with both undergraduate and postgraduate research                                          at ways to rejuvenate the age–dependent
trainees recently joining his laboratory.                                   decline in the stress axis. Recently, Bailey adopted a poochon whom
                                                                            she keeps an eye on with a remote camera. Puppies can be
                         While she may not feel new to the
                                                                            mischievous after all!
                         Department, Meghan Jeanotte is actually our
                         relatively   recent   new   addition   as   the    Jitendra Kumar Tripathi (postdoctoral fellow) also joined our team!
                         Department’s       administrative   associate.     Dr. Tripathi obtained his Ph.D. from Jawaharlal Nehru University in India,
                         Meghan spent seven years as an EPA                 where his work was focused on “understanding the structure-function
                         manager at the Turtle Mountain tribe before        relationship in naturally occurring antimicrobial peptides and the
                         joining us. She is the engine that runs the        design of their novel analogues.” Dr. Tripathi joined UND’s Department
                         Department, managing personnel, budgets,           of Biomedical Sciences as a postdoctoral fellow and has explored the
grants, and educational efforts. Meghan is the mother of two lovely         molecular signaling of host-pathogen interaction, with special
children and is pursuing her BA degree in psychology at UND. Quite          attention to bacterial pneumonia (pneumosepsis). He has extensive
the go – getter, eh? If all her work and effort weren’t enough, Meghan      work experience with transgenic mouse strains as preclinical disease
will shortly oversee a new departmental educational program directed        mouse models. He joins the Department of Geriatrics in collaboration
towards nursing homes and their quality improvement.                        with Dr. Nadeem Khan (Biomedical sciences), and is investigating the
                                                                            molecular mechanism of aging, immune/cellular senescence, and its
                                                                            relation to influenza-associated bacterial pneumonia.
                                                                                                                          ...continued on next page
GERIATRICS NEWS - UND School of Medicine
N EW FA C U LT Y
                 AND STAFF                        Continued

Dr. Trishna Debnath is another new postdoctoral fellow. She             Marsha Waind, MOTR/L, CHT, CLT, is our most recent staff member
completed her Ph.D. in advanced applied life science from Konkuk        to join the Department as project director for Geriatrics Telehealth.
University in the Republic of Korea in 2014. She comes to UND with      Marsha recently retired from Altru Health System as director of their
an extensive research background that includes more than 50 research    telehealth and virtual care program, and with some gentle arm twisting
articles in peer-reviewed scientific journals. Her research interests   we were able to call Marsha out of retirement to activate our
include functional foods chemistry and immunology.                      interprofessional telehealth training program. This program has two
                                                                        goals and is funded by HRSA as a COVID-19 response project. The
                        Upon activation of the HRSA–funded Dakota
                                                                        first goal is to teach older adults about how to successfully access
                        Geriatrics GWEP, we were fortunate to have
                                                                        telehealth services; the second goal is to teach health care trainees
                        Sarah Owens and Casey Morton join us as
                                                                        on how to optimally conduct a team–based telehealth encounter. We
                        Project Director and Manager, respectively.
                                                                        are particularly impressed with Marsha’s success in reaching out.
                        Sarah is an established UND staff member
                                                                        Marsha is married and is an empty-nester with three children and five
                        who transferred from the University Analytics
                                                                        grandchildren. In her spare time, she enjoys reading, lake time, and
                        & Planning office to join the Geriatrics
                                                                        walks with the doggo.
                        Department. Sarah has previous experience
Sarah Owens
                        with managing federal projects as part of her   Finally, Peni Rosten joined us as a project assistant for the
                        job with the Women’s Health initiative. Sarah   Department and GWEP. Peni recently received her bachelor’s degree
                        is concurrently pursuing a doctoral degree in   in digital marketing. Prior to coming to UND, Peni worked 13 years at
                        education at UND. Her organizational skills     Altru Health System in the clinical area. Originally from western North
                        and managerial finesse have accelerated gain    Dakota, Peni has spent the past 15 years in Grand Forks and is
                        in a Dakota Geriatrics program that has         married. She has two children: Brady (10) and Graham (8), as well as
                        multiple moving parts. Particularly adept at    and English cream golden retriever, Cruise (5). In her spare time, she
                        cultivating programmatic partnerships, Sarah    enjoys traveling, cooking, lake time, and baking with her boys.
                        is helping build academic, community, and
Casey Morton
                        health    center    collaborations    towards
strengthening geriatrics education and age–friendly communities.
Sarah is married and is the mother of twin daughters, and enjoys
spending time with family and friends. Casey Morton joined the
Department with considerable experience in clinical management at
the local community teaching hospital, Altru Health System. She is in
charge of several complex and ambitious projects for Dakota
Geriatrics, namely population health, social media, and our online
curriculum. Casey was instrumental in working with medical students
over the summer in compiling evidence-based geriatrics data for
publication in our social media platforms. Uniquely, Casey has
partnered with Assistant Professor Nicolle Derenne, Ph.D., from UND’s
Department of Art & Design to create age–pertinent imagery to piggy-
back onto citations and annotated commentaries distributed to social
media platforms. Research shows that people pay closer attention to
social media posts linked to imagery than just script.
GERIATRICS NEWS - UND School of Medicine
GERIAT R IC M E D I C I N E F E L L O WS HI P PROGRAM
UPDATED TO CONTINUED ACCREDITATION
The relatively new Geriatric Medicine Fellowship celebrates its third          Anjandeep Hara, M.D.
class of Geriatric Fellows. Drs. Annie Hara and Carol Johnson joined           Dr. Hara grew up in Vancouver, British Columbia, and completed her
the fellowship program this past summer. Given the pandemic                    family medicine residency at UND prior to starting her fellowship. She
situation, the fellowship had some challenges, but the program quickly         became interested in Geriatrics due to the complexity of the patients
adapted. Fellows are involved in telehealth and increased their                and the opportunity to use a variety of means to improve quality of life
homecare visitations. With great reluctance to visit the geriatric clinic,     and independence.
many older adults are missing their annual wellness exams and routine
                                                                               Although geriatric medicine fellowships are typically undersubscribed
care for many of their chronic conditions. Similar to the national
                                                                               across the country, and only 50% of the programs nationwide fill their
situation, this shortcoming has led to a spike in cancer and
                                                                               programs, UND has been fortunate to have a steady stream of trainees
uncontrolled chronic conditions such as hypertension, heart failure,
                                                                               with two of the past three years seeing the program 100 percent filled!
and chronic lung disease.

                                                                               Additional good news regarding the fellowship is that the program was
Carol Johnson, M.D.
                                                                               founded on an ACGME designation of “exceptional merit,” with a
Dr. Johnson is a UND alumna. She majored in biology and minored in
                                                                               recent recertification of the program for 10 years. The program design
women’s studies and english literature for her undergraduate studies.
                                                                               is innovative, with fellows gaining experience in quality improvement,
She then graduated from the UND School of Medicine & Health
                                                                               geriatric models of healthcare, and telehealth. Most gratifying is the
Sciences in 2000. She did her family medicine residency in Tulsa,
                                                                               fact that all three of our past fellows have become academic faculty
Oklahoma, and entered practice at Regina Medical Group in Hastings,
                                                                               at medical schools.
Minnesota. She recently relocated to Fargo to be closer to family and
is pursuing further training in geriatrics, which has always been a
strong interest for her.

GERIAT R IC S
RESEARCH
Publications: One of our Department’s publications was highlighted             inflammatory conditions such as Alzheimer's disease and Parkinson's
as one of the “top five” articles published in the Journal of Gerontology      disease in late life, although the mechanism is not well understood.
in 2020!                                                                       He says: “The overarching goal overarching goal of my laboratory
                                                                               research is to understand the regulatory mechanism of low-grade
The study reveals that heat shock (HS) response declines with age.
                                                                               inflammation and identify drug candidates to alleviate aging pathology.
The attenuated response entails changes in HSF1–protein
                                                                               Our recent findings suggest that autophagy protects gut epithelial
interactions potentially driven by loss of HSF1 protein levels and gain
                                                                               damage, and impaired autophagy results in severe colitis in the atg7
of negatively regulating heat shock proteins, thus emphasizing the
                                                                               ablated CX3Cr1Atg7f/f TNBS mouse. Autophagy describes as a highly
inhibitory    loop      of   HSF1–DNA          binding.     Age-dependent
                                                                               conserved catabolic pathway that assists in the sequestration and
posttranslational modifications of HSF1 also appear to affect its
                                                                               removal of unwanted cellular debris. A decline in autophagy function
transactivating      properties,   including    loss   of   the   activating
                                                                               reported in aging people, and induction of autophagy, has been shown
phosphoserine 326 residue as well as accumulation of HSF1
                                                                               to alleviate longevity. To determine autophagy and mitophagy function
acetylation, which is known to block HSF1–DNA binding. Thus, age
                                                                               in regulating mucosal inflammaging, we created a series of knockout
affects the heat shock axis at multiple levels. Our recently published
                                                                               mouse lines ablating autophagy and mitophagy function in Villin
review from the Journal of Experimental Gerontology explains the key
                                                                               epithelial CX3Cr1 resident macrophage cells. We are now interested
features of the HS response that are likely targets of aging processes
                                                                               in investigating the underlying regulatory cellular, molecular, and
and then examines evidence of a multifactorial mechanism that
                                                                               epigenetic factors utilizing pharmaceutical, epigenetic, functional
renders a sub-optimal stress response. Additionally, the review
                                                                               assay, and mouse genetic tools. Given the autophagy and the
summarizes how the stress response is further altered by late-life
                                                                               mitophagy process involved in mucosal inflammation, further
diseases and the potential for therapeutically manipulating the stress.
                                                                               understanding of the regulatory mechanisms would be indispensable

Dr. Ram Mathur is actively publishing on: age-dependent chronic                to the prevention of aging pathologies.”

inflammation, which is linked to colon cancer and other neuro-
GERIATRICS NEWS - UND School of Medicine
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Department of Geriatrics                                                                                                                  Grand Forks ND
1301 N Columbia Rd Stop 9037                                                                                                                Permit #10
Grand Forks, ND 58202
Phone: 701.777.6949
med.UND.edu/geriatrics

NEW
FACULTY
With great excitement and anticipation, we are pleased to announce                                    Dr. Syed Haris Ali is currently our newest
the successful recruitment of Jeremy Holloway, Ph.D., who will                                        community faculty member as a physician
become an educational scholar-track, assistant professor in the                                       and scholar. He trained in anatomy and
Department of Geriatrics. Jeremy wowed the faculty search committee                                   carried out doctoral-level research in medical
with his charisma, eloquence, and commitment to diversity. He is a                                    education at the UND School of Medicine &
freshly minted Ph.D., and has already created an educational program                                  Health Sciences. Thereafter, he trained in
that links undergraduate students with older adults in assisted living                                UND’s Internal Medicine Residency as well as
through video chat encounters with the intention of creating a booklet                                our own Geriatrics Fellowship programs.
for older adults that recount their life’s milestones. This timely project   Since then, he has been working in hospital medicine and devoting
addresses social isolation and loneliness looming in congregate senior       time to the new Geriatrics Workforce Enhancement Program by
housing due to the COVID–19 pandemic. Jeremy is married to Kayla,            participating in undergraduate geriatrics curriculum development,
who works in the cardiac unit at the Toledo Promedica Hospital. They         knowledge dissemination via social networking platforms, and
are the proud parents of three children (Anaya, Asher, Grace) and are        assessment of knowledge via multiple-choice questions. Dr. Ali finds
expecting a fourth child in Nov. 2020 as of this writing. Dr. Holloway       his scholarly work to be highly relevant to day-to-day clinical practice.
will provide faculty oversite of the Dakota Geriatrics program, assuring
effective educational design and programming, especially online, and
curricular assessment. Equally importantly, Dr. Holloway will work with
UND’s Diversity and Inclusion office to advance under-resourced and
under-represented trainees. Dr. Holloway developed a program to
optimize academic performance of minority students.
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