Medical Biodefense Conference 2021 - Venue

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Medical Biodefense Conference 2021 - Venue
Medical Biodefense
         Conference 2021
                      28 Sep - 1 Oct 2021, Munich
                       **Preliminary program**
                             as of 7 September 2021

Venue
Bundeswehr Medical Academy
Neuherbergstrasse 11
80937 Munich
Germany
Medical Biodefense Conference 2021: Preliminary program

Program at a Glance

                               –2–
Medical Biodefense Conference 2021: Preliminary program

29.09.2021 (09:00 - 10:30)

Session A
Opening session
chaired by Roman Wölfel and Lars Schaade

 TalkID   Speaker           Title                                                           Duration

 A1       Bernd             Welcome notes by the Director Science and deputy                10+0 min
 [990]    Mattiesen         commander of the Bundeswehr Medical Academy
          Munich, DEU

 A2       Roman Wölfel      Welcome Notes by the Conference Chair and Institute Director    25+0 min
 [998]    Munich, DEU       of the Bundeswehr Institute of Microbiology

 A3       Andrew D.         For Whom the Bell Tolls: The Global Challenges posed by New     55+0 min
 [260]    Green             and Emerging Infectious Diseases
          Birmingham,
          GBR

29.09.2021 (11:00 - 12:30)

Session B
Outbreak and epidemic management
chaired by Gelimer Genzel and Ines Mergler

 TalkID   Speaker           Title                                                           Duration

 B1       Ines Mergler      Strengthening the United Nations Secretary-General’s            20+5 min
 [79]     Berlin, DEU       Mechanism (UNSGM) during times of COVID-19 pandemic-
                            related restrictions

 B2       Jonathan W.       The British Army’s approach to science and technology in an     12+3 min
 [252]    Ashcroft          ever-changing world
          London, GBR

 B3       Julia K. Burr     Requirements for the Implementation of COVID-19 Control         12+3 min
 [188]    Alexandria, VA,   Measures Given Prevailing Rates of Vaccine Compliance
          USA

 B4       Benjamin          Strategic autonomy (self-sufficiency) of Europe for supply of   12+3 min
 [199]    Queyriaux         CBRN medical counter-measures
          Munich, DEU

 B5       Ralf Wörl         Safe containments, tailored to the application – up-scaling,    12+3 min
 [227]    Elmshorn, DEU     modification, integration, combination and complete
                            enclosures

                                                 –3–
Medical Biodefense Conference 2021: Preliminary program

29.09.2021 (13:30 - 15:30)

Session C
Information for action - Surveillance and epidemiology
chaired by Robert von Tersch and Kai Kehe

 TalkID   Speaker              Title                                                          Duration

 C1       Robert von Tersch    US Army Public Health Center Laboratory Pilot Waste            20+5 min
 [281]    Aberdeen Proving     Water Surveillance for SARS-CoV-2
          Ground, MD, USA

 C2       Rudolf Markt         Concept for a wastewater-based SARS-CoV-2 monitoring           12+3 min
 [247]    Innsbruck, AUT       in the multinational UN Military Camp Castor Gao (Mali)

 C3       Carsten Tiemann      Lessons learned: Large SARS-CoV-2 “Tönnies” outbreak           15+5 min
 [89]     Bad Salzuflen, DEU   with 1800 positive cases in a slaughterhouse - military
                               support, laboratory challenge and sequencing results
                               (NGS)

 C4       Markus               Innovation in the crisis: Outbreak detection of SARS-CoV-2     12+3 min
 [83]     Antwerpen            - Molecular diagnostics and epidemiology as a team
          Munich, DEU

 C5       Dimitrios            How electronic situation maps (SITMAP) and Dashboards          12+3 min
 [275]    Frangoulidis         can help to fight information gaps during disaster relief as
          Munich, DEU          in the SARS-CoV-2-pandemic

 C6       Erny Niederberger    Selective threat detection of airborne biological particles    12+3 min
 [96]     Horw, CHE            in real time by new AI based monitoring systems from
                               Swisens

 C7       Akinyemi M.          CoxBase: an online platform for epidemiological                12+3 min
 [82]     Fasemore             surveillance, visualization, analysis and typing of Coxiella
          Munich, DEU          burnetii genomic sequences

                                                –4–
Medical Biodefense Conference 2021: Preliminary program

29.09.2021 (13:30 - 15:30)

Session D
Four- and eight-legged warriors
chaired by Gerhard Dobler and Johannes P. Borde

 TalkID   Speaker        Title                                                             Duration

 D1       Gulnar         Circulation of arthropod-borne infections in Kazakhstan           12+3 min
 [255]    Omasheva
          Almaty, KAZ

 D2       Dmitrii O.     Molecular Epidemiology and Structure of the Diversity of          12+3 min
 [235]    Kiselev        Pathogens of Tick-Borne Infections of the Genus Borrelia in
          Irkutsk, RUS   Natural Foci of the Baikal Region of Russia

 D3       Simone         Prevalence of bacterial and viral zoonoses in dromedary camels    12+3 min
 [215]    Eckstein       from southern Tunisia
          Munich, DEU

 D4       Saskia         Seroprevalence and risk factors for hantavirus-disease and        12+3 min
 [174]    Schmitz        leptospirosis in a hantavirus high-risk region in Lower Saxony,
          Hannover,      2019
          DEU

 D5       Edith          Prevalence of Puumala and Tula orthohantaviruses in               12+3 min
 [213]    Wagner         Clethrionomys glareolus and Microtus spp. in Thuringia, Germany
          Munich, DEU

 D6       Florian        The changing epidemiology of human monkeypox – a potential        12+3 min
 [74]     Lienert        threat? A systematic review
          Zug, CHE

                                               –5–
Medical Biodefense Conference 2021: Preliminary program

29.09.2021 (16:00 - 18:00)

Session E
Phylogenetics and genetic diversity
chaired by Gregor Grass and Wolfgang Beyer

 TalkID   Speaker           Title                                                            Duration

 E1       Ben Krause-       New life for old bones - A 5,000-year-old hunter-gatherer        25+5 min
 [272]    Kyora             already plagued by Yersinia pestis
          Kiel, DEU

 E2       Gilles            How old is Bacillus anthracis?                                   25+5 min
 [77]     Vergnaud
          Gif-sur-Yvette,
          FRA

 E3       Sara D.           Phylogeny of Francisella tularensis in Switzerland using whole   12+3 min
 [246]    Schütz            genome sequencing
          Spiez, CHE

 E4       Jörg Linde        Whole-Genome-Sequencing Based High-Resolution Genotyping         12+3 min
 [170]    Jena, DEU         of Francisella tularensis and Bacillus anthracis in Germany

 E5       Caroline          Reorganized Genomic Taxonomy of Francisellaceae Enables          12+3 min
 [205]    Öhrman            Design of Robust Environmental PCR Assays for Detection of
          Umeå, SWE         Francisella tularensis

 E6       Ansgar            Whole-genome sequencing of various (neglected) arboviruses       12+3 min
 [216]    Schulz            circulating in Africa using MinION nanopore technology
          Greifswald,
          DEU

                                                  –6–
Medical Biodefense Conference 2021: Preliminary program

29.09.2021 (16:00 - 18:00)

Session F
Case reports and educational session
chaired by Sabine Zange and Dieter Hoffmann

 TalkID   Speaker               Title                                                      Duration

 F1       Susann Dupke          Heatwave associated Vibrio infections in Germany           20+5 min
 [206]    Berlin, DEU           2018 and 2019

 F2       Christiane P.         Surprising diagnosis in a patient with pericardial         15+5 min
 [226]    Tiefenbacher          effusion
          Wesel, DEU

 F3       Frank Sitterlee       The Hunter and the Hip                                     15+5 min
 [263]    Neubrandenburg, DEU

 F4       Johannes P. Borde     Three patients with diseases of different etiology after   20+5 min
 [231]    Oberkirch, DEU        tick bite in Southern Germany

 F5       Sonja Mantel          A case of community-aquired pneumonia in a security        15+5 min
 [230]    Munich, DEU           guard in times of Corona

                                            –7–
Medical Biodefense Conference 2021: Preliminary program

30.09.2021 (08:30 - 10:30)

Session G
Last minute highlights - aspects of zoonotic infections - from detection to therapy
chaired by Rosina Ehmann and Steve Lonsdale

 TalkID   Speaker            Title                                                           Duration

 G1       Jean-Lou Marié     SARS-CoV-2 antibodies seroprevalence in dogs from France        12+3 min
 [95]     Tours, FRA         using ELISA and an automated western blotting assay

 G2       Esther Schalke     Scent dog identification of SARS-CoV-2-infections - double      12+3 min
 [286]    Ulmen, DEU         blind studies

 G3       Ulrich Schotte     Selected Biological Agents from the Veterinary Perspective      12+3 min
 [192]    Kronshagen,
          DEU

 G4       Laura              Use of Botulism Antitoxin Heptavalent (A, B, C, D, E, F, G) -   12+3 min
 [63]     Cochrane           (Equine) (BAT®) in Clinical Study Subjects and Patients: A
          Tewkesbury,        15-Year Systematic Safety Review
          GBR

 G5       Michela            Discovery of New SARS-CoV-2 Inhibitors                          12+3 min
 [201]    Puxeddu
          Rome, ITA

 G6       Isabel Hunger-     The new WHO BioHub at the Spiez Laboratory                      12+3 min
 [75]     Glaser
          Spiez, CHE

 G7       Lokesh Joshi       A nature inspired approach to pathogen binding for              12+3 min
 [288]    Galway, IRL        decontamination, sample collection and diagnostics

 G8       F. Nina            A novel immunization platform for the elicitation of potent     12+3 min
 [287]    Papavasiliou       antibodies that block opioid intoxication and prevent
          Heidelberg, DEU    overdose

                                                 –8–
Medical Biodefense Conference 2021: Preliminary program

30.09.2021 (08:30 - 10:30)

Session H
A tight match: host vs. pathogen
chaired by Haim Levy and Heiner von Buttlar

 TalkID   Speaker                  Title                                                  Duration

 H1       Haim Levy                The neglected virulence factor – Role of the capsule   20+5 min
 [292]    Ness Ziona, ISR          in Bacillus anthracis pathogenicity

 H2       Yasuyuki Tsunoi          Viability improvement of three-dimensional             12+3 min
 [179]    Tokorozawa, JPN          cultured skin substitutes by photobiomodulation

 H3       Voahangy                 Long- term persistence of humoral immune               12+3 min
 [202]    Andrianaivoarimanana     response against plague in Malagasy patients
          Antananarivo, MDG

 H4       Marina Šantic            Francisella tularensis-one peculiar and possibly       12+3 min
 [76]     Rijeka, HRV              emerging pathogen

 H5       Jan Bavlovic             Study of the secretion of outer membrane vesicles      12+3 min
 [274]    Hradec Králové , CZE     in the bacterium F. tularensis and their role in the
                                   host - pathogen interaction

 H6       Rakhmanbek Toichuev      The effect of disturbed colonization resistance of     12+3 min
 [187]    Osh, KGZ                 the gastrointestinal tract on the incidence and
                                   features of the course of typhoid fever disease and
                                   the formation of typhoid carrier status in uranium
                                   biogeochemical zones

 H7       Gvantsa Brachveli        Multiple SARS-CoV-2 Mutations in an                    12+3 min
 [250]    Tbilisi, GEO             Immunocompromised Oncology Patient

                                             –9–
Medical Biodefense Conference 2021: Preliminary program

30.09.2021 (11:00 - 12:30)

Session I
New tools for stationary and mobile diagnostics (Part 1 of 2)
chaired by Katrin Zwirglmaier and Heinrich Scheiblauer

 TalkID   Speaker            Title                                                            Duration

 I1       Kilian Stoecker    Pulse-Controlled Amplification – a new powerful tool for         12+3 min
 [125]    Munich, DEU        front-line diagnostics

 I2       Agnieszka          Using the rapid antigen test for COVID-19 diagnostics in the     12+3 min
 [197]    Wozniak-Kosek      Hospital Emergency Department of the Military Institute of
          Warsaw, POL        Medicine in Poland

 I3       Heinrich           Comparative sensitivity evaluation for 122 CE-marked SARS-       12+3 min
 [175]    Scheiblauer        CoV-2 antigen rapid tests
          Langen, DEU

 I4       Julia T. Klüpfel   Rapid detection of (neutralizing) SARS-CoV-2 antibodies by       12+3 min
 [70]     Munich, DEU        chemiluminescence microarray immunoassay

 I5       Rosina Ehmann      A murderer´s diary and portfolio: Different ways of              12+3 min
 [280]    Munich, DEU        inactivation of SARS-CoV-2 for diverse downstream purposes

 I6       Stephen C.         Development of an inexpensive, disposable, pre-symptomatic       12+3 min
 [224]    Francesconi        agnostic diagnostic of infectious disease to determine fitness
          Ft. Belvoir, VA,   for duty and preempt potential for contagious spread
          USA

                                               – 10 –
Medical Biodefense Conference 2021: Preliminary program

30.09.2021 (11:00 - 12:30)

Session J
The dose makes the poison: An update on the detection of biological toxins
chaired by Mandy Knüpfer and Brigitte G. Dorner

 TalkID   Speaker              Title                                                           Duration

 J1       Brigitte G. Dorner   European programme for the establishment of validated           20+5 min
 [116]    Berlin, DEU          procedures for the detection and identification of biological
                               toxins (EuroBioTox)

 J2       Andreas              Development of a multiplex algae toxin immunoassay for          12+3 min
 [248]    Auernhammer          the monitoring of algal blooms in surface water
          Munich, DEU

 J3       Jiri Dresler         In-situ Detection of Botulinum Neurotoxin A by MALDI            12+3 min
 [94]     Prague, CZE          Mass Spectrometry Using Functionalized Chips

 J4       Maren Krüger         A multiplex biochip for fast and sensitive detection of eight   12+3 min
 [118]    Berlin, DEU          biotoxins for differential diagnosis of ricin intoxications

 J5       Sylvia Worbs         Differentiation, Quantification and Identification of Abrin     12+3 min
 [194]    Berlin, DEU          and Abrus precatorius Agglutinin

                                                – 11 –
Medical Biodefense Conference 2021: Preliminary program

30.09.2021 (13:30 - 15:30)

Session K
New tools for stationary and mobile diagnostics (Part 2 of 2)
chaired by Kilian Stoecker and Ben Gannon

 TalkID   Speaker                Title                                                        Duration

 K1       Jan Baumann            Classification and Standardization of Rapid Response         12+3 min
 [284]    Geneva, CHE            Mobile Laboratories

 K2       Veronika Merold        Development and Validation of rRNA Targeted Reverse          12+3 min
 [73]     Munich, DEU            Transcription Real Time PCR Assays for the Sensitive
                                 and Rapid Diagnostics of High Consequence Pathogens

 K3       Lovasoa N.             Rapid and efficient detection of Yersinia pestis in plague   12+3 min
 [110]    Randriantseheno        biological samples using the loop-mediated isothermal
          Antananarivo, MDG      amplification

 K4       Gregor Grass           A unique single nucleotide polymorphism in multi-copy        12+3 min
 [114]    Munich, DEU            16S rRNA genes and transcripts facilitates sensitive
                                 identification of Bacillus anthracis by real time PCR

 K5       Mostafa Bentahir       Nucleic acids isothermal amplification methods for fast      12+3 min
 [249]    Brussels, BEL          and reliable detection of biothreat agents: potential for
                                 on-site use in operational conditions

 K6       Aleksandr S. Safatov   The use of biochips with SOI-FET sensors for the             12+3 min
 [177]    Novosibirsk, RUS       indication of viruses in aerosol samples

                                               – 12 –
Medical Biodefense Conference 2021: Preliminary program

30.09.2021 (13:30 - 15:30)

Session L
Dual-use-research of concern
chaired by Roman Wölfel and Isabel Hunger-Glaser

 TalkID   Speaker            Title                                                           Duration

 L1       Filippa            History and Politics of DURC Governance                         25+5 min
 [204]    Lentzos
          London, GBR

 L2       R. Guy Reeves      Self-spreading vaccines in the environment: An innovation or    20+5 min
 [293]    Plön, DEU          the erosion of an evidence-based norm?

 L3       Thomas             Responsible handling of security-relevant research in           20+5 min
 [214]    Lengauer           Germany
          Saarbrücken,
          DEU

 L4       Svenja Vinke       The biosecurity education gap: Most life-sciences researchers   15+5 min
 [241]    Bielefeld, DEU     have never heard of the term “dual use research”

                                                – 13 –
Medical Biodefense Conference 2021: Preliminary program

30.09.2021 (16:00 - 18:00)

Session M
Antimicrobials and vaccines
chaired by Gerd Sutter and Ruth Brack-Werner

 TalkID   Speaker              Title                                                        Duration

 M1       Gerd Sutter          Vaccination against COVID-19 - the development of            20+4 min
 [291]    Munich, DEU          candidate vaccine MSARSCoV2

 M2       Ariane               An MVA-based WEVEE vaccine protects mice against all 3       10+2 min
 [147]    Volkmann             equine encephalitis viruses and is safe and immunogenic in
          Martinsried, DEU     a Phase 1 trial

 M3       Stuart N. Isaacs     Development of a next generation subunit smallpox vaccine    10+2 min
 [232]    Philadelphia, PA,    using nucleoside-modified mRNA
          USA

 M4       Douglas W.           Smallpox Preparedness: Integrating TPOXX® into Response      10+2 min
 [245]    Grosenbach           Planning
          Corvallis, OR, USA

 M5       Gamal Wareth         WGS based analysis of antimicrobial resistance, MLST and     10+2 min
 [90]     Jena, DEU            motility in Acinetobacter baumannii in the One-Health
                               context in Germany

 M6       Michael Hust         Fighting pathogens and toxins with recombinant antibodies    10+2 min
 [59]     Braunschweig,
          DEU

 M7       Steve G. Lonsdale    Modernising Antibody Discovery for Biodefence                10+2 min
 [144]    Salisbury, GBR       (Dstl/CP133015)

 M8       Dominic              Design of a new model system for viral fusion                10+2 min
 [91]     Hayward
          Garching, DEU

 M9       Scott A. Seitz       Advancement of a small molecule antiviral therapeutic to     10+2 min
 [244]    Boston, MA, USA      treat Poxvirus infection

                                                – 14 –
Medical Biodefense Conference 2021: Preliminary program

30.09.2021 (16:00 - 18:00)

Session N
International Biosecurity
chaired by Erik Tintrup and Gordon Wilke

 TalkID   Speaker        Title                                                           Duration

 N1       Erik Tintrup   The Federal Foreign Office’s engagement in Biosafety and        12+3 min
 [81]     Berlin, DEU    Biosecurity: Reducing global biological threats in a
                         collaborative effort

 N2       Bourema        Role of the mobile laboratory in the response to the COVID-19   12+3 min
 [153]    Kouriba        pandemic in the region of Timbuktu, Mali
          Bamako, MLI

 N3       Mohamed Ben    The Tunisian Rapid Response Team and Mobile Laboratory –        12+3 min
 [242]    Moussa         From Training and Field Exercises to Providing Essential
          Tunis, TUN     Diagnostic Support for Tunisia during the COVID-19 pandemic

 N4       Lela           Awareness Raising Campaign in the Framework of EU               12+3 min
 [212]    Bakanidze      Chemical, Biological, Radiological and Nuclear (CBRN) Centers
          Tbilisi, GEO   of Excellence (CoE) Initiative in Central Asia

 N5       Eva Mertens    Introducing the ‘Global Partnership Initiated Biosecurity       12+3 min
 [127]    Hamburg, DEU   Academia for Controlling Health Threats (GIBACHT) – COVID-19
                         Strategy (COST-19)’ Initiative to strengthen the SARS-CoV-2
                         response in partner countries

 N6       Nur            Tula Orthohantavirus (TULV) as the predominant species in       12+3 min
 [136]    Turkhanova     three regions in Kazakhstan
          Munich, DEU

 N7       Anna Shin      Characterization of TBEV in Kazakhstan by serological and       12+3 min
 [124]    Almaty, KAZ    molecular biological methods

 N8       Maryna Y.U.    Oral fluid-based surveillance study of African Swine Fever      12+3 min
 [119]    Kit            amoung wild boars in Ukraine
          Kharkiv, UKR

                                             – 15 –
Medical Biodefense Conference 2021: Preliminary program

01.10.2021 (08:30 - 10:10)

Session O
Bacteriophages against highly pathogenic and MDR bacteria: from diagnostics to therapy
(Part 1 of 2)
chaired by Peter Braun and Samuel N. Kilcher

 TalkID   Speaker          Title                                                            Duration

 O1       Samuel N.        Reporter Phage-Based Detection of Bacterial Pathogens: Design,   25+5 min
 [195]    Kilcher          Engineering, and Application
          Zurich, CHE

 O2       Jiemin Du        Rapid Detection of Bacterial UTIs via Reporter Phage-Based       12+3 min
 [196]    Zurich, CHE      Bioluminescence Assay

 O3       Peter Braun      Recombinant receptor binding proteins of bacteriophages as       20+5 min
 [236]    Munich, DEU      versatile tools for pathogen detection

 O4       Nadja            Enzyme-linked phage receptor binding protein assay (ELPRA)       12+3 min
 [238]    Rupprich         enables identification of Bacillus anthracis
          Munich, DEU

 O5       Andrew           Arming bacteriophages with colicins for more effective killing   12+3 min
 [151]    Millard
          Leicester, GBR

                                                – 16 –
Medical Biodefense Conference 2021: Preliminary program

01.10.2021 (10:30 - 12:30)

Session P
Bacteriophages against highly pathogenic and MDR bacteria: from diagnostics to therapy
(Part 2 of 2)
chaired by Christian Willy and Brett E. Swierczewski

 TalkID   Speaker              Title                                                          Duration

 P1       Martha Clokie        Phage Therapy in Europe                                        20+5 min
 [283]    Leicester, GBR

 P2       Alla                 Initial host range analysis of commercial phage preparations   12+3 min
 [123]    Yushchenko           on Ukrainian MRSA isolates
          Kyiv, UKR

 P3       Alexander            Learning from bacteriophages how to overcome the               12+3 min
 [150]    Harms                resilience of antibiotic-tolerant, dormant bacteria
          Basel, CHE

 P4       Jana Stender         Isolation, characterization and engineering of lytic           12+3 min
 [156]    Munich, DEU          bacteriophage TUN1 specific for Klebsiella pneumoniaeK64
                               clinical isolates from Tunisia

 P5       Holger Ziehr         Bacteriophages – Old antiinfectives with new perspectives      12+3 min
 [225]    Braunschweig,
          DEU

 P6       Kilian Vogele        A cell-free platform for production, modification and          12+3 min
 [115]    Garching, DEU        engineering of bacteriophages for therapeutic use

 P7       Brett E.             Therapeutic Bacteriophage Cocktails for Compassionate Use      12+3 min
 [203]    Swierczewski         against Multidrug-Resistant Infections
          Silver Spring, MD,
          USA

01.10.2021 (12:30 - 13:00)

Session Q
Poster awards and farewell
chaired by Roman Wölfel, Arne C. Rodloff, and Herbert Schweizer

                                                 – 17 –
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