Rapport sur les contributions - XVth Rencontres du Vietnam International Conference on Medical Physics and School - IN2P3
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XVth Rencontres du Vietnam
International Conference on
Medical Physics and School
Rapport sur les
contributions
https://indico.in2p3.fr/e/19513XVth Rencontres … / Rapport sur les contributions Forward-backward asymmetry in t …
Contribution ID: 8 Type: not specified
Forward-backward asymmetry in top production
through z’ bosons
There are only a few experimental hints towards deviation from standard model and one such
example is top quark‘s asymmetry that can lead us to physics beyond Standard Model. We consider
one phenomenological model containing an extra neutral boson to characterize the new physics
that may be responsible for this deviation. We estimate the amount of this asymmetry in this
model. this model capture some generic effects of alarge number of theories such as Technicolor
and Little Higgs Mode.
April 7, 2020 Page 1XVth Rencontres … / Rapport sur les contributions Applications of quantum groups to …
Contribution ID: 21 Type: not specified
Applications of quantum groups to standard model
phenomenology
Replacing the classical groups in the Standard Model (SM) by their quantum group counterparts
is motivated from the consideration of both Lie and Hopf type (quantisation) deformations. A
quantisation deformation deforms the universal enveloping algebra of a Lie algebra into a quantum
group.
Taking the quantum group SUq(3) as a flavor symmetry, including second order symmetry break-
ing and considering electromagnetic contributions, we derive q-deformed octet and decuplet baryon
mass relations accurate to 0.02% and 0.08% respectively as well as a new relation between the octet
and decuplet masses accurate to within 1.0%.
As gauge groups, quantum groups introduce additional degrees of freedom suggestive of non-
locality, forming the basis of a soliton theory of massive particles. A similar approach in the
literature where particles are described as braids has led to the idea that the SM is emergent from
quantum spacetime.
Further applications of quantum groups to Cabibbo mixing, and neutrino oscillations are discussed.
Orateur: Dr GRESNIGT, Niels (Xi’an Jiaotong-Liverpool University Suzhou, Jiangsu, China)
April 7, 2020 Page 2XVth Rencontres … / Rapport sur les contributions PET imaging in radiotherapy treat …
Contribution ID: 36 Type: not specified
PET imaging in radiotherapy treatment planning
lundi 29 juillet 2019 09:15 (30 minutes)
Summary
Orateur: Prof. VISVIKIS, Dimitris (INSERM)
April 7, 2020 Page 3XVth Rencontres … / Rapport sur les contributions Research and development of CT, …
Contribution ID: 37 Type: not specified
Research and development of CT, MRI, SPECT and
PET images segmentation software for automatic
detection and extraction of brain tumors using ITK,
VTK, Qt
lundi 29 juillet 2019 09:45 (30 minutes)
In the field of medical image processing, detection of brain tumor from computed tomography (CT)
or magnetic resonance (MRI) scans is a difficult task due to complexity of the brain hence it is one
of the top priority goals. In this work, we describe a new method which combines four different
steps including smoothing, Sobel edge detection, connected component and finally region grow-
ing algorithms for locating and extracting the various lesions in the brain. The analysis results
indicate that the proposed method automatically and efficiently detected the tumor region from
the CT or MRI image of the brain. It is very clear for physicians to separate the abnormal from
the normal surrounding tissue to get a real identification of related area; improving quality and
accuracy of diagnosis, which would help to increase success possibility by early detection of tumor
as well as reducing surgical planning time. This is an important step in calculating the correct dose
of radiation therapy later. The computational algorithm proposed method was implemented using
POCTA - a new software combining 3 tools: Insight Toolkit (ITK) to process input image, Visual-
ization Toolkit (VTK) to display and Qt software development framework to build user interface
Summary
Orateur: THAO, Ho Thi (Vietnam Acad. Science and Technology)
April 7, 2020 Page 4XVth Rencontres … / Rapport sur les contributions Quantitative CT imaging for airwa …
Contribution ID: 38 Type: not specified
Quantitative CT imaging for airway structure and
lung function
lundi 29 juillet 2019 10:45 (30 minutes)
Aim
Using a recently developed quantitative computed tomography (QCT), this study explored segmen-
tal and parenchymal features of cement dust exposed (DE) subjects vs. non-dust exposed (NDE)
subjects.
Methods
We employed 58 DE (Kangwon National University Hospital, KNUH) and 142 NDE subjects (Chon-
buk National University Hospital, CNUH). Segmental structural metrics of airway diameter, wall
thickness, and bifurcation angle were extracted. We extracted parenchymal functional metrics
including inspiratory capacity (IC), percent emphysema (Emph%), and percent functional small
airway disease (fSAD%).
Results
Regarding segmental structural metrics, DE subjects had airway narrowing at the 2-5-th genera-
tion (pXVth Rencontres … / Rapport sur les contributions Early diagnosis of insulinoma usin …
Contribution ID: 39 Type: not specified
Early diagnosis of insulinoma using PET: from cell
culture to (pre)-clinical in vivo imaging
lundi 29 juillet 2019 11:15 (30 minutes)
Insulinoma is a rare, usually solitary and benign neuroendocrine tumor (NET). It is characterized
by inappropriate and uncontrolled insulin production and secretion, with consequent glycopenic
symptoms and potentially lethal hypoglycemia. Early detection of the tumor is crucial, allowing
curative treatment by surgical enucleation. The localization of insulinoma remains challenging,
and conventional PET imaging is the first method used for diagnostic investigation.
Patient premedication with carbidopa seems to improve the accuracy of 6-18F-fluoro-3,4-dihydroxy-
L-phenylalanine (18F-FDOPA) PET for insulinoma diagnosis. Carbidopa is capable of drastically
reducing physiologic pancreatic uptake, with a consequent increase in the tumor-to-background
ratio. However, no final consensus about the usefulness of carbidopa premedication before 18F-
FDOPA PET in patients with hyperinsulinemic hypoglycemia has been reached because of the
potential reduction of tumoral uptake intensity.
The present study represents the first preclinical research study focused on insulinomas, with a
potential impact on the diagnostic and therapeutic management of patients in clinical practice.
First, we developed an insulinoma xenograft model in mice and managed to keep the animals
all along the study, despite a relatively high mortality due to the high insulin production of tu-
mors. Secondly, we assessed two different radio-labeled molecules, according to the biological
pathways describing the tumor model. In vitro and in vivo experiment were conducted to investi-
gate the tumor uptake of both O-(2-18F-fluoroethyl)-L-tyrosine (18F-FET) and carbidopa-assisted
18F-FDOPA radiotracers. Finally, dynamic 18F-FET and carbidopa-assisted 18F-FDOPA PET scans
were performed on tumor-bearing nude mice after subcutaneous injection of tumor cells and on
a 30-year-old man with type-1 multiple endocrine neoplasia and hyperinsulinemic hypoglycemia
defined by a positive fasting test.
Results showed structural analogies between 18F-FET and 18F-FDOPA as well as the limited pan-
creatic uptake of 18F-FET in human, which suggests evaluating 18F-FET as diagnostic radiotracer
for insulinoma detection in further prospective studies involving large cohorts of patients. This
research work illustrates the multidisciplinary aspect of medical physics, which involves physics,
chemistry and biology to answer a medical question. A specific focus will be put on infrastructures,
instrumentations and methodologies which enabled this study.
Summary
Orateur: Dr BOISSON, Frédéric (IPHC)
April 7, 2020 Page 6XVth Rencontres … / Rapport sur les contributions Characterization of EBT3 Films re …
Contribution ID: 40 Type: not specified
Characterization of EBT3 Films response to
ionization radiations
jeudi 1 août 2019 11:00 (30 minutes)
ARRONAX facility serves partially as a user facility for research. It hosts a multi-particle acceler-
ator that can produce a wide quality of radiation (particle type and energy): protons from 17 MeV
up to 70 MeV, and alpha-particles at a fixed energy of 68 MeV. ARRONAX proton beam is therefore
adapted for preclinical research on cells or small animals. The beam, made of pulses delivered at a
given frequency, can be produced with a large range of intensities from low (XVth Rencontres … / Rapport sur les contributions Range verification in proton thera …
Contribution ID: 41 Type: not specified
Range verification in proton therapy: the LAPD
demonstrator and its originalapproach to in-beam
PET ballistic control
lundi 29 juillet 2019 11:45 (30 minutes)
In this presentation, original results obtained with the Large Area Pixelized Detector (LAPD) for in-
beam ballistic control of hadrontherapy treatments are described. The LAPD system is a PET-like
demonstrator built in order to test the feasibility of monitoring in real time, during irradiation, the
ion range in the patient through the measurement of the beam-induced beta+ activity distribution.
It has been designed with the aim of testing a few new and original solutions to overcome some
of the in-beam PET challenges. These solutions are presented and their performances evaluated
with data acquired with the 65 MeV proton beam of the Nice (France) protontherapy center are
discussed. In particular, it is shown that the LAPD allows to monitor and detect in real time shifts
of 1 mm in Bragg peak position in polymethyl methacrylate targets. Then, data to Monte Carlo
simulation comparisons are presented and the performances on simulation of the activity profile
reconstruction algorithm are described. The new high bandwidth LAPD data acquisition system
will also be briefly discussed.
Summary
Orateur: Prof. BUSATO, Emmanuel (LPC, Clermont)
April 7, 2020 Page 8XVth Rencontres … / Rapport sur les contributions SBRT portal dosimetry based on M …
Contribution ID: 42 Type: not specified
SBRT portal dosimetry based on Monte Carlo
simulation
lundi 29 juillet 2019 13:30 (30 minutes)
Stereotactic radiation body therapy (SBRT) treatments require the implementation of robust pre-
treatment and in-vivo dosimetry methods, to which electronic portal imaging devices (EPIDs) offer
an attractive solution. However the development of EPID-based dosimetry models adapted to com-
plex SBRT conditions is still challenging and is not completely supported for some EPID models
and by commercial solutions. Therefore, in this work a detailed Monte Carlo (MC) model of the
linac in combination with EPID is purposed to accurately predict the absorbed dose to the detector
for further SBRT in vivo dosimetry applications.
The MC simulation platform GATE/Geant4, was used to simulate the radiation transport through
the detailed geometry of a previous validated model of a Varian TrueBeam STx, where the geome-
try of the aS1000 EPID was also implemented. Varian phase-space source files (PSFs) were used to
simulate 6 MV FFF photon beams and to obtain secondary PSFs at linac exit and EPID scintillator
layer, in which absorbed dose was calculated for field sizes ranging from 0.5x0.5 to 15x15cm2, and
for a complete dynamic SBRT treatment. Corresponding EPID images were acquired in integrated
and continuous modes, at 150 cm distance from the source and were compared to the MC calcu-
lated ones by means of relative dose difference maps and dose profiles, and global gamma index
for the whole treatment.
Results showed the suitability of the MC model in predicting EPID response for non-transit dosime-
try with integrated images for simple fields and also dynamic SBRT treatments with continuous
EPID imaging. However, in the latter, important discrepancies were still observed, mainly for
points located at zones of higher dose gradients. This could also be related to the differences
found between planned and delivered treatment parameters, and should be considered to improve
simulation results and for further SBRT EPID in vivo dosimetry.
Summary
Orateur: Dr BARBEIRO, A. Rita (INSERM)
April 7, 2020 Page 9XVth Rencontres … / Rapport sur les contributions SIMULATION Simulation of I-131 …
Contribution ID: 43 Type: not specified
SIMULATION Simulation of I-131
radiopharmaceutical of thyroid cancer
lundi 29 juillet 2019 14:00 (30 minutes)
I-131 is utilized for thyroid radiotherapy by giving radioactive I-131 in thyroid gland. As it in-
volves ionizing radiation, it is important to ensure that the patients receive optimum amount of
radiation to destruct the target tissue while keeping the radiation-related side effects to minimum.
In clinical practice, standard activity doses are preferred for thyroid cancer patients, assuming that
biokinetics are similar in all patients. Lately, many clinicians offered to individualize the radioac-
tive iodine therapy by calculating the optimal amount of radioactivity using patient dosimetry.
Radiation dosimetry is used to calculate the minimum effective and maximum tolerated absorbed
dose for a successful radioactive iodine therapy. This approach enables to administer increased
amount of therapeutic activity while minimizing the related side effects. In this study, the SAF
values in critical organs were calculated using mesh-type adult ICRP phantoms to evaluate the
risk of treatment. The results were compared with those of previous researchs based on others
phantoms and thermoluminescent dosimeter.
Summary
Orateur: M. THANG, Nguyen Tat (Hanoi Univ. Science and Technology (HUST))
April 7, 2020 Page 10XVth Rencontres … / Rapport sur les contributions Using the Geant4-DNA toolkit for …
Contribution ID: 44 Type: not specified
Using the Geant4-DNA toolkit for estimating RBE of
diverse radiation qualities
lundi 29 juillet 2019 14:30 (30 minutes)
Ionizing radiation can induce damage in the DNA of living beings. This damage can be repair by the
cell but sometimes this does not happen so the functioning of the cell is altered, leading to cell death
or cancer. This problem is of primordial importance in areas such as radiation therapy of cancer,
radiation protection, and aerospace industry. The Monte Carlo (MC) method have the ability to
simulate the transport of ionizing particles through matter. We have developed a biophysical model
based in the combination of MC simulations, a DNA geometrical model with atomic resolution, and
a methodology for linking the energy deposition process to the DNA damage. This model has been
successfully applied for estimating the relative biological effectiveness (RBE) of different primary
radiation qualities, including low energy photons, energetic ions, and fast neutrons. Results of
some recent studies will be presented.
Summary
Orateur: Prof. BERNAL, Mario (State University of Campinas)
April 7, 2020 Page 11XVth Rencontres … / Rapport sur les contributions Simulation of liver cancer treatme …
Contribution ID: 45 Type: not specified
Simulation of liver cancer treatment using 90Y
microspheres based on anatomical image
segmentation technique and Geant4 toolkit
lundi 29 juillet 2019 15:30 (30 minutes)
The 90Y is a type of therapeutic isotope which have maximum beta energy of 2.23 MeV, the pen-
etration in tissues about 1.1 cm and its half-life of 64.1 hours. Therefore, it is widely used in
brachytherapy, especially in the hepatocellular carcinoma and other liver cancers. The quality of
the treatment depends largely on the dose calculation in regimen planning. There are some dose
calculation methods: (I) Body Surface Area method (BSA), (II) Empiric method, and (III) Partition
method. All of these method are analytic or empiric methods. There have been some studies
showing the limitations in accuracy of these methods. This study would present an approach to
calculate dose in treatment planning. By using anatomical segmentation techniques to define ge-
ometry of liver and tumor for construct the simulation geometry. Besides, the distribution of 90Y
in the liver also determined by this method. The material of liver/tumor is determined via CT
number-densities based on Hounsfield scale. We are developing several semi-empirical models
and implement to the Geant4 toolkit to simulate the interaction of the electron with matter and
deposited dose distribution in the patient liver.
Summary
Orateur: M. HA, Nguyen Hong (Vietnam Acad. Science and Technology)
April 7, 2020 Page 12XVth Rencontres … / Rapport sur les contributions Functions and Interfaces in Particl …
Contribution ID: 46 Type: not specified
Functions and Interfaces in Particle Therapy System
Simulation Framework
lundi 29 juillet 2019 16:00 (30 minutes)
The particle therapy system simulation framework (PTSIM) is a Geant4 based simulation for parti-
cle therapy, which simulates radiation transport in a treatment port consisting of a beam delivery
system and a treatment head with patient geometry. It is used in proton and carbon therapy fa-
cilities for validating treatment plans and improving irradiation systems. Although the PTSIM
supports event-level parallelism in multithread and distributed computing environments on CPU-
based architecture, the dose calculation under clinical treatment parameters requires more than
several hours. To overcome the problem, the MPEXS project has developed a GPU-based Monte
Carlo simulation for electromagnetic process and recently extended it to the hadronic processes
of protons (MPEXS-proton). It is capable of completing the dose calculation within a few minutes.
However, validation of the simulation against the measurements in the treatment port requires
additional efforts and time. On the other hand, since each particle therapy facility has a validated
PTSIM simulator, PTSIM can be used to prepare the phase space data of the beam delivery system.
Using that data, MPEXS-proton can perform the dose calculation of patient geometry. In this pa-
per, we report on the overall functionality of PTSIM and interfaces of phase space data relevant to
the MPEXS project.
Summary
Orateur: M. ASO, Tsukasa (Toyama College)
April 7, 2020 Page 13XVth Rencontres … / Rapport sur les contributions DRecent development of solid stat …
Contribution ID: 47 Type: not specified
DRecent development of solid state microdosimetry
and its applications in particle therapy
mardi 30 juillet 2019 08:30 (30 minutes)
Particle therapy has many advantages over conventional photon therapy, particularly for treating
deep-seated solid tumours due to its greater conformal energy deposition achieved in the form
of the Bragg peak (BP). Successful treatment with protons and heavy ions depends largely on
knowledge of the relative biological effectiveness (RBE) of the radiation produced by primary and
secondary charged particles. The RBE prediction based on microdosimetric approach using the
tissue equivalent proportional counter (TEPC) measurements in 12C therapy has been reported,
however large size of commercial TEPC is averaging RBE which dramatically changes close to
and in a distal part of the BP that may have clinical impact. Moreover, the TEPC cannot be used
in current particle therapy technique using pencil beam scanning (PBS) delivery due to pile up
problems associated with high dose rate in PBS.
Based on many years of experience in development of silicon-on-insulator (SOI) microdosimeter,
the Centre for Medical Radiation Physics, University of Wollongong, has successfully developed
a microdosimetric probe which is based on a SOI microdosimeter with 3D micron sized sensi-
tive volumes (SVs) mimicking dimensions of cells, known as the “Bridge” and “Mushroom” micro-
dosimeters, to address the shortcomings of the TEPC [1, 2]. The silicon microdosimeters provide
extremely high spatial resolution and were used to evaluate the RBE of 290 MeV/u 12C, 180 MeV/u
14N and 400 MeV/u 16O ions at Heavy Ion Medical Accelerator in Chiba (HIMAC), Japan [3] as
well as to measure the microdosimetric distributions of a proton pencil-beam scanning (PBS) and
passive scattering system at the Massachusetts General Hospital (MGH) Francis H. Burr Proton
Beam Therapy Center, USA [4]. Preliminary cell survival experiments on proton therapy beam in
conjunction with SOI microdosimetry demonstrated good correlation between cell survival based
RBE and predicted RBE based on measured dose average lineal energy with developed probe and
microdosimetric kinetic model (MKM).
References:
[1] Rosenfeld A. “Novel detectors for silicon based microdosimetry, their concepts and applica-
tions”, Nucl. Instrum. Methods., Phys. Res. A 809, 156–170, February 2016
[2] Linh T. Tran et. al., “Thin Silicon Microdosimeter utilizing 3D MEMS Technology: Charge Col-
lection Study and its application in mixed radiation fields”, IEEE Transactions on Nuclear Science,
Volume: 65, Issue: 1, 467-472, Jan. 2018.
[3] Linh T. Tran, et. al., “The relative biological effectiveness for carbon, nitrogen and oxygen ion
beams using passive and scanning techniques evaluated with fully 3D silicon microdosimeters”
Medical Physics, 2018 , DOI10.1002/mp.12874.
[4] Linh T. Tran, et. al., “Characterisation of proton pencil-beam scanning using a high spatial
resolution solid state microdosimeter”, Medical Physics, doi: 10.1002/mp.12563, 2017.
Summary
Orateur: Dr TRAN, Thuy Linh (Centre for Medical Radiation Physics, University of Wollongong,
Australia)
April 7, 2020 Page 14XVth Rencontres … / Rapport sur les contributions Preliminary Study for in-vivo dosi …
Contribution ID: 48 Type: not specified
Preliminary Study for in-vivo dosimetry of the small
animal irradiation
mardi 30 juillet 2019 09:00 (30 minutes)
This study assessed applications for in-vivo dosimetry using a 3D printer-based, self-manufactured
mouse immobilization device in a small field. The mouse immobilization device was created using
a 3D printer (Makerbot Replicator, MakerBot Industries, Brooklyn, NY, USA) and consisted of the
support flat, fixing units, sensor areas, and a build-up cap. Radio-photoluminescence glass dosime-
ters (RPLGD, GD-302M) were inserted at the upper left (UL), upper right (UR), lower left (LL), and
lower right (LR) of the device at the center of the target. EBT3 film was inserted into the device
at the top of the mouse’s head. Irradiation planning was performed using the ECLIPSE system
after a CT simulation of mice with an immobilization device. The mice were irradiated 5 times
at a dose 180 cGy with 6 MV X-rays. The dose measurements from the RPLGDs and films were
compared with the doses calculated in the Eclipse system. The percentage differences between the
Radiation Treatment Planning (RTP) System and RPLGD measurements were 5.56 ± 3.90%, 6.52 ±
5.32%, 10.0 ± 8.97%, and 15.9 ± 17.5% at the UL, UR, LL, and LR positions, respectively. The gamma
passing rate of all film measurements exceeded 90% in the 2%/2 mm range. The error values of the
3rd measurements were outliers due to the set up. With the exception of the 3rd measurements,
the percentage difference decreased to 4–7%. In this study, we evaluated the applicability of a
mouse immobilization device in a small field. We performed in-vivo dosimetry using RPLGD and
EBT3 film; this approach may be helpful for using radiation to accurately analyze results in animal
studies.
Summary
Orateur: Dr KIM, Dong Wook (Yonsei Cancer Center)
April 7, 2020 Page 15XVth Rencontres … / Rapport sur les contributions Film Dosimetry in Radiotherapy
Contribution ID: 49 Type: not specified
Film Dosimetry in Radiotherapy
mardi 30 juillet 2019 09:30 (30 minutes)
Summary
Orateur: Prof. ARDJO PAWIRO, Supriyanto (Indonesia Univ.)
April 7, 2020 Page 16XVth Rencontres … / Rapport sur les contributions Detector for Dosimetry on LINAC …
Contribution ID: 51 Type: not specified
Detector for Dosimetry on LINAC and MedPhys
education at CMRP
mardi 30 juillet 2019 10:30 (30 minutes)
An increase in the complexity of contemporary radiation oncology technologies demand sophis-
ticated medical devices for verification of treatment delivery. The Centre for Medical Radiation
Physics (CMRP) is an internationally recognised leader in the development of radiation detectors,
providing real time high spatial and temporal resolution for treatment verification in radiation
therapy.
Pre-treatment and real time in-vivo treatment delivery verification in brachytherapy was resolved
with the recently developed “Magic Phantom” and “BrachyView”. These systems allow fast verifi-
cation of source dwelling and radioactive seed positions with submillimeter resolution for in-vivo
real-time verification.
Real-time motion adaptive radiotherapy aims to reduce the impact of patient-specific changes in
anatomy during treatments through re-optimisation of the treatment delivery. Multi leave collima-
tor (MLC) tracking utilises real-time tumour localisation to adjust the MLC configuration during
delivery. Patient specific quality assurance of treatments employing MLC tracking is complex
as daily variations in the patient’s tumour motion create new adaptations. We have developed
a family of 2D high spatial and temporal resolution pixelated detectors (“Magic Plate”) to verify
real-time motion adaptive radiotherapy delivery.
The lecture will be devoted to present advances in medical dosimetry on LINAC, brachytherapy,
interventional radiology using innovative semiconductor sensors.
References
M. Petasecca, M.K. Newall, J.T. Booth, et al “MagicPlate-512: a two dimensional silicon detector
array for Quality Assurance of stereotactic motion adaptive radiotherapy” Med.Phys., 42(6) , 2992-
3004, 2015
M. Safavi-Naeini, Z. Han, D. Cutajar, et al. ”BrachyView, A novel in-body imaging system for HDR
prostate brachytherapy: Experimental evaluation”, Med Phys , 2015
Anatoly.B.Rosenfeld “Novel detectors for silicon based microdosimetry, their concepts and appli-
cations”, NIM A, 809, 156-170, 2016
Summary
Orateur: Dr TRAN, Thuy Linh (Centre for Medical Radiation Physics, University of Wollongong,
Australia)
April 7, 2020 Page 17XVth Rencontres … / Rapport sur les contributions OpenDose: a Free Online Database …
Contribution ID: 52 Type: not specified
OpenDose: a Free Online Database of Dosimetric
Data for Nuclear Medicine
mardi 30 juillet 2019 11:00 (30 minutes)
Dosimetry in Nuclear Medicine uses a common formalism (MIRD) using pre-calculated reference
Specific Absorbed Fractions and S Values. Such data is generated with Monte Carlo simulations
for specific models and radioisotopes and is often computationally intensive. OpenDose is an
international collaboration to generate, verify and disseminate reference dosimetric data. Using
a common framework, every team provide reproducible data, with every value associated with
uncertainty. The dosimetric data is then processed and stored in a SQL database and accessed
through a newly created website. The website is designed to give the Nuclear Medicine community
a free and easy access to dosimetric data.
Summary
Orateur: Dr CHAUVIN, Maxime (INSERM)
April 7, 2020 Page 18XVth Rencontres … / Rapport sur les contributions TPS Transition of dose calculation …
Contribution ID: 53 Type: not specified
TPS Transition of dose calculation method in
radiation therapy and the State of Art of treatment
planning system
jeudi 1 août 2019 09:00 (30 minutes)
In radiation therapy, simulation of dose distribution in the patient’s body plays a major role in de-
termining the quality of treatment. In the past, tissue inhomogeneity corrections for mega voltage
photon beams could change the prescribed dose by 10% in lung cancer. The impact showed the
importance of the dose calculation method. For the dose calculation in treatment planning sys-
tems, model-based algorithms have been used to shorten the calculation time. However, with the
recent increase in calculation speed, accurate dose calculation algorithms such as the Boltzmann
transport equation or the Monte Carlo method are spreading. Our facility also has implemented
in-house Monte Carlo method for proton dose calculation. The in-house Monte-Carlo method re-
produced measured dose distributions in a heterogeneous phantom better than the conventional
pencil beam method. As a recent topic, biological effect prediction models are being introduced
for treatment planning systems. This is an interesting area in the field of particle beam therapy,
and a biological effect prediction model focusing on LET dependency has been developed. This
talk reviews the transition of dose calculation method in radiation therapy and introduce the State
of Art of treatment planning system.
Summary
Orateur: M. HOTTA, Kenji (Nat. Cancer Center Hospital )
April 7, 2020 Page 19XVth Rencontres … / Rapport sur les contributions Radiotherapy and Nuclear medicin …
Contribution ID: 54 Type: not specified
Radiotherapy and Nuclear medicine in Kien Giang
province: A review of current practice and future
development
jeudi 1 août 2019 14:30 (30 minutes)
Radiotherapy and Nuclear medicine are particularly interested in Kien Giang, a southen province
of Viet Nam. This paper provides several brief reviews about the development in Radiotherapy and
Nuclear medicine in Kien Giang. In 2010, the first LINAC (Primus 5599) with four independent
jaws was equiped. Hundreds of cancer patients were delivered by Primus 5599 each year with
3D-CRT and JO-IMRT techniques. The JO-IMRT technique has applied since 2016 for head and
neck cases. Besides, a new modern LINAC (Clinac iX) with MLC-120 leaves has been installed
in 2019 to perform high precise techniques such as IGRT and VMAT. To complete radiotherapy
modality for cervical cancer patients, the Remote Afterloading Brachytherapy Unit has also been
operated by using 192Ir isotope. Nuclear medicine specialty has been built recently that is related
to the application of radioactive subtances in the diagnosis and treatment of disease. The Cyclotron
18MeV system will be operated to produce some radionuclides including 18F, 15O, 13N, 11C, and
124I. The QA/QC devices ,such as HPLC and HPGe, are equiped to assure the quality of produced
radionuclides before injecting into patients. In addition, radiation detectors are placed at suitable
location to keep safety all time. Nuclear medical images are required by PET-CT and SPECT (dual
heads) units which were installed in 2017.
Summary
Orateur: TU, Vu Ngoc
April 7, 2020 Page 20XVth Rencontres … / Rapport sur les contributions PROTONS AND HADRONS Histo …
Contribution ID: 55 Type: not specified
PROTONS AND HADRONS History and Physics of
Particle Therapy
mercredi 31 juillet 2019 08:30 (1 heure)
This lecture will present the history and physics of ion particle therapy, especially using protons
and carbon ions. In 1946, Robert R. Wilson first proposed a possible therapeutic application of ion
beams in his famous paper “Radiological Use of Fast Protons”. During the 50ths, in Berkeley (CA,
US), the team of R. R. Wilson, John & Ernest Lawrence, and C. A. Tobias underlined the poten-
tial benefits of using heavy charged particles in radiotherapy. The pioneering work performed in
Berkeley using p, d, 4He, 12C, 20Ne, 28Si and 40Ar during 1948-1992 will be discussed, and the first
accelerator facility dedicated to carbon ion therapy, the Heavy Ion Heavy Ion Medical Accelerator
in Chiba (HIMAC), will be described. The lecture will also give an update of all currently operat-
ing carbon ion facilities, and discuss the physical and radiobiological differences between photon,
proton and carbon ion therapy. Especially the advantages of treating deep seated radioresistant
hypoxic tumor cells with carbon ions will be discussed. The need for precise on-line range verifi-
cation during ion therapy will be argued since range shifts might occur due to e.g. movements of
the patient, movement of an organ, miss positioning of the patient, tumor shrinkage, filling of a
cavity due to infections, etc. In the end there will be a summary and a future outlook.
Summary
Orateur: Prof. SIHVER, Lembit (TU Wien, Atominstitut)
April 7, 2020 Page 21XVth Rencontres … / Rapport sur les contributions Medical application of nuclear phy …
Contribution ID: 56 Type: not specified
Medical application of nuclear physics
mercredi 31 juillet 2019 09:30 (30 minutes)
Summary
Orateur: Prof. YAMAYA, Taiga (QST Hospital International Therapy Research Center)
April 7, 2020 Page 22XVth Rencontres … / Rapport sur les contributions Current and future of independent …
Contribution ID: 57 Type: not specified
Current and future of independent dose calculation
using Monte Carlo in Nagoya Proton Therapy Center
mercredi 31 juillet 2019 10:30 (30 minutes)
More than two thousand patients have been treated by using proton beam at Nagoya Proton Ther-
apy Center (NPTC) since 2013. The NPTC has both scanning and broad beam irradiation systems.
Broad beam irradiation is mainly used to treat prostate and tumors with respiratory movements
such as lung and liver, while scanning irradiation is mainly used for head and neck, bone and soft
tissue, and pediatric cancer. The MC dose calculation for second dose check by using PTSIM which
is a Geant4-based simulation framework for particle therapy has been carried out. It takes a half
day to complete the MC dose calculation for one patient by using a CPU-based PC Linux cluster. In
order to respond to more flexible changes in treatment plans, we plan to speed-up MC dose calcu-
lation by introducing a GPU-based Monte Carlo simulation system called MPEXS-proton, which is
capable of electromagnetic and hadronic processes in Geant4 on CUDA framework. It will take less
than a few minutes to complete the dose calculation for one patient. The MPEXS-proton system
will be a promising device for dose calculation in proton therapy.”
Summary
Orateur: M. TOSHITO, Toshiyuki (Nagoya Proton Therapy Center)
April 7, 2020 Page 23XVth Rencontres … / Rapport sur les contributions Organ Motion and Image Guidance
Contribution ID: 58 Type: not specified
Organ Motion and Image Guidance
mercredi 31 juillet 2019 11:30 (30 minutes)
Summary
Orateur: Dr ZHANG, Ye (PSI)
April 7, 2020 Page 24XVth Rencontres … / Rapport sur les contributions The design status of beamline syst …
Contribution ID: 59 Type: not specified
The design status of beamline system and gantry
room of SC200 proton therapy
mercredi 31 juillet 2019 13:30 (30 minutes)
Summary
Orateur: Dr ZHENG, Jinxing (Chinese Acad. Sciences)
April 7, 2020 Page 25XVth Rencontres … / Rapport sur les contributions Progress in Proton Therapy Enabl …
Contribution ID: 60 Type: not specified
Progress in Proton Therapy Enabled by Technology
mercredi 31 juillet 2019 11:00 (30 minutes)
Summary
Orateur: Dr GROSSMANN, Martin (Paul Scherrer Institute)
April 7, 2020 Page 26XVth Rencontres … / Rapport sur les contributions Controls for SC200
Contribution ID: 61 Type: not specified
Controls for SC200
mercredi 31 juillet 2019 14:00 (30 minutes)
Summary
Orateur: M. FENG, Hansheng (Chinese Acad. Sciences)
April 7, 2020 Page 27XVth Rencontres … / Rapport sur les contributions Carbon Fragmentation for Hadron …
Contribution ID: 63 Type: not specified
Carbon Fragmentation for Hadron Therapy
mercredi 31 juillet 2019 14:30 (30 minutes)
Hadrontherapy treatments require a high accuracy on the dose deposition to keep the benefits of
the precise ions ballistic. One of the sources of uncertainty on physical dose deposition is due to
the fragmentation of the incident ion (fragmentation tails behind the tumor, RBE fluctuation in
depth). Up to now, the simulation codes are not able to reproduce the fragmentation process with
the precision required for treatments. The constraints on nuclear models and fragmentation cross
sections in the energy range used in hadrontherapy are not yet sufficient. The maximum energy
of GANIL, 95 MeV/u allows to constrain the low part of energies used for treatments. To improve
the models and reach the precision required for a reference simulation code for hadrontherapy,
experiments have been performed by our collaboration on thick target of medical interest in 2008,
on thin targets at 95 MeV/u in 2011 and 2013 and at 50 MeV/u in 2015. The experimental set-up
included five three stages ΔE-E telescopes composed of two Si detectors and one CsI scintillator.
These telescopes were mounted on rotating stages to cover angles from 0 to 45°. Double differ-
ential cross section in energy and solid angle, of fragments resulting from nuclear reactions of
12C ions with PMMA and thin targets (C; CH2 ; Ti; Al; Al2O3) have been measured. The data of
the experiments have already been analyzed and compared to GEANT4 simulations (BIC, jQMD,
INCL++). The data have also been compared to codes included in PHITS (jQMD). Experimental
results compared to GEANT4 and PHITS simulations of 50 and 95 MeV/u 12C cross sections on the
different targets will be presented. We plan to do systematic measurements of fragmentation cross
section of 12C on thin targets of medical interest for hadrontherapy (up to 400 MeV/u). A large
acceptance mass spectrometer is under developpement. It will be composed of a beam monitor,
a target, upand downstream trackers surrounding a magnet and a time-of-flight (ToF) wall. First
beam tests of the beam monitor and the ToF wall will be performed at GANIL in june 2019. The
FRACAS setup will be described.
Summary
Orateur: Prof. LABALME, Marc (LPCCaen)
April 7, 2020 Page 28XVth Rencontres … / Rapport sur les contributions Open Discussion: How to build an …
Contribution ID: 64 Type: not specified
Open Discussion: How to build and operate proton
therapy center: Experiences for Vietnam
mercredi 31 juillet 2019 15:30 (2 heures)
Summary
Orateur: Prof. CUONG, Phan Viet
April 7, 2020 Page 29XVth Rencontres … / Rapport sur les contributions RT Screening method to follow up …
Contribution ID: 65 Type: not specified
RT Screening method to follow up thyroid cancer
patients after thyroidectomy
jeudi 1 août 2019 14:00 (30 minutes)
This paper present a cost effective and simple screening method to follow up thyroid cancer pa-
tients who have had their thyroid surgically removed (thyroidectomy), without any metastases,
and have been declared stable or cured. The method is based on using a small NaI (Tl) detector sys-
tem and oral intake of 131I, to measure the concentrated radioactive iodine uptake (RAIU), together
with measurements of levels of protein Thyroglobulin (Tg) in the blood. It is shown that measure-
ments of RAIU together with Tg measurements can with high precision detect re-occurrence of
thyroid cancer. Due to its simplicity and cost effectiveness, the presented method could be used
at any local nuclear medicine department/medical center at the Vietnamese countryside, far away
from the main hospitals. Then, if there are indications for a cancer re-occurrence, the patients
could be sent to a major hospital to undergo a planar head and neck or full body single-photon
emission computed tomography (SPECT) scan. If needed, follow up treatment with 131I could also
be performed at the local nuclear medicine departments/medical centers. This would significantly
reduce the costs for the patients and reduce the burden at the large/major hospitals.
Summary
Orateur: Prof. SIHVER, Lembit (TU Wien, Atominstitut)
April 7, 2020 Page 30XVth Rencontres … / Rapport sur les contributions Local Hypertermia
Contribution ID: 67 Type: not specified
Local Hypertermia
jeudi 1 août 2019 09:30 (30 minutes)
Hyperthermia (also known as thermotherapy) is generally regarded as a mean body or tumor
tissue temperature higher than normal. The processing of increasing temperature is realized by
three methods: local, regional and whole- body hyperthermia. Local hyperthermia has become a
recognized and quite widespread adjuvant method of chemotherapy and / or radiation treatment
of resistant tumors by using different techniques: Electromagnetic (EM) and Ultrasound wave
that have reviewed. The technique selection depends on properties of tumors. The combination
between method of local and radio/or chemo has applied successfully in the “N. N. Blokhin National
Medical Research Centre of oncology” of the Health Ministry of Russia.
Summary
Orateur: Mlle NHUNG, Duong (MEPI)
April 7, 2020 Page 31XVth Rencontres … / Rapport sur les contributions DETECTORS 18F-FDG autoradiog …
Contribution ID: 68 Type: not specified
DETECTORS 18F-FDG autoradiography with CMOS
sensor in murine models of lupus
jeudi 1 août 2019 10:00 (30 minutes)
Nuclear imaging is essential in the clinical and pre-clinical field for studying the biodistribution
of the drug and observing the evolution of the pathology. Positron Emission Tomography (PET)
scan is today a gold standard with picomolar sensitivity for functional in vivo imaging. It offers
millimeter-scale spatial resolution . Autoradiography, with Mimosa-28 semiconductor digital sen-
sors, provides a sub-millimetre resolution while keeping a good sensitivity in order to visualize the
cerebral distribution of the radiotracer 18F-FDG in the mouse. Preliminary, this sensor is charac-
terized with isotope usually used in preclinical systems in the PET system: 18F. Measurements of
efficiency and spatial resolution are made to compare with other current systems such as emulsion
films, phosphorescence, scintillation and gaseous detectors.
PET scans enable to explore biodistribution at the animal scale before to visualize the distribution
with autoradiography at the tissue scale. We then explore the possibility of improving the quality
of images through GEANT4 Application for Tomography Emission (GATE) Monte-Carlo simu-
lation and reconstruction using a Maximum Likelihood Estimation Method (MLEM) algorithm.
The autoradiographic images gain in contrast and the scattering of the charged particles into the
medium is attenuated.
Summary
Orateur: M. TRUONG GIANG, Nguyen Pham (IPHC)
April 7, 2020 Page 32XVth Rencontres … / Rapport sur les contributions Ion beam monitoring using brems …
Contribution ID: 70 Type: not specified
Ion beam monitoring using bremsstrahlung X-rays
jeudi 1 août 2019 11:30 (30 minutes)
Particle therapy provides a high and localized deposited dose to the target tumor thanks to the
Bragg Peak. Then, the development of online beam monitoring tools with non-invasive methods
represents an important challenge. Some studies deal with the use of prompt gamma radiations
to localize the Bragg Peak, with a resolution of several millimeters. A novel promising approach
using the detection of the bremsstrahlung X-rays is actually investigating, and requires improve-
ments. Both methods have performance mainly limited by counting statistics and noise signal.
These latter depend on the fundamental parameters such as cross sections. For that purpose, the
work presented consists firstly to valid a theoretical model of the bremsstrahlung cross sections
with experimental measurements. Secondly, the feasibility to use the bremsstrahlung X-rays com-
ing from a PMMA target and a water tank, as a biological medium surrogate, in order to monitor
proton beams was studying.
An experimental set-up was designed to irradiate a PMMA target and a water tank with pro-
ton beams in the energy range from 17MeV/u to 50MeV, delivered by the ARRONAX cyclotron.
A silicon drift detector measured the bremsstrahlung X-rays. A model based of the theoretical
bremsstrahlung cross sections5 was developed to compare the experiment data to simulations.
The differential cross sections were previously measured on carbon target to compare the results
to data available in the literature6.
Cross sections were measured in the range of 10 mbarn.keV-1 to 1000 mbarn.keV-1. A signifi-
cate agreement was found with the model and the literature. Moreover, simulations fitted the
bremsstrahlung spectra of the PMMA target confirming the significate sensibility of the method
(104 X-rays/nC detected) and the validation of the ion bremsstrahlung model. Proton beam energy
can be monitored using the bremsstrahlung X-rays thanks to the spectrum hardening, due to the
variation of the bremsstrahlung cross sections. These results are encouraging in order to localized
the proton beam range. Fundamental studies are also expected to link the bremsstrahlung signal
to the deposited dose in the biological medium, in order to apply the method to dosimetry and
medical applications
Summary
Orateur: M. RALITE, Flavien (SUBATECH)
April 7, 2020 Page 33XVth Rencontres … / Rapport sur les contributions Development of a diamond hodosc …
Contribution ID: 71 Type: not specified
Development of a diamond hodoscope for online ion
range monitoring in hadrontherapy
jeudi 1 août 2019 13:30 (30 minutes)
The ballistic property of ion beams is a key issue in hadrontherapy. Online ion range assessment
during treatment would permit to fully exploit this advantage. In this context, Prompt-Gamma
(PG) imaging using a Compton camera has been proposed by the French CLaRyS collaboration.
The originality of the system is the use of a beam-tagging hodoscope that would provide tempo-
ral and spatial information on the incoming ions. This hodoscope at first relied on an array of
scintillating fibres. To reach higher counting rate and a timing resolution of 100 ps, the collabora-
tion has initiated recently the development of a diamond hodoscope. (CLaRyS Ultra Fast Timing).
Diamond were selected for their very fast response and radiation hardness. Initially, for charac-
terization purposes, pad detectors made of Chemical Vapor Deposition (CVD) single-crystal and
polycrystalline diamonds as well as Diamonds grown On Iridium (DOI) were built. Then, to satisfy
the position-sensitive criterion in the hodoscope prototyping, double-side stripped demonstrators
were designed and assembled with custom discrete current preamplifiers at LPSC in Grenoble.
Both pad and strip detectors have been characterized under various irradiation conditions. At
GANIL, a 18 ps RMS Time-Of-Flight resolution has been obtained between a single-crystal and a
DOI pad detectors with 95 MeV/u 12C ions. The same two detectors exhibit a 59 ps RMS Time-Of-
Flight resolution when tested with 68 MeV protons in ARRONAX-Nantes. Single 68 MeV proton
detection efficiency has been evaluated with two 1 cm² pad detectors: one polycrystalline and
one DOI. The results are respectively 92% and 50%. Finally, stripped sensors were tested with a
8.5 keV pulsed X-Ray micro-beam at European Synchrotron Radiation Facility. A 100% detection
efficiency and a 103 ps RMS time resolution were measured at several strips crossings with the
polycrystalline sample. In conclusion, present results encourage, in a near future, the develop-
ment of a larger area prototype made of four diamonds in a mosaic arrangement and read by a
dedicated and integrated fast readout electronics currently developed at LPSC.
Summary
Orateur: M. CURTONI, Sébastien (LPSC)
April 7, 2020 Page 34XVth Rencontres … / Rapport sur les contributions ISOTOPES Radio-isotope producti …
Contribution ID: 72 Type: not specified
ISOTOPES Radio-isotope production at ELI-NP
vendredi 2 août 2019 08:30 (30 minutes)
Summary
Orateur: Dr CUCOANES, Andi (ELI-NP)
April 7, 2020 Page 35XVth Rencontres … / Rapport sur les contributions A proposition for a cancer treatme …
Contribution ID: 73 Type: not specified
A proposition for a cancer treatment study using
radioisotope metal cofactor enzymes
vendredi 2 août 2019 09:00 (30 minutes)
Summary
Orateur: VAN LUYEN, Tran
April 7, 2020 Page 36XVth Rencontres … / Rapport sur les contributions Radionuclide spatial distribution m …
Contribution ID: 74 Type: not specified
Radionuclide spatial distribution measurement and
dose deposition for in vitro assessments of targeted
alpha therapy
vendredi 2 août 2019 09:30 (30 minutes)
Introduction. The interest of Targeted Alpha Therapy (TAT) for diffuse cancer or metastatic lesions
is increasing because of the short range and the high linear energy transfer (LET) of α-particles.
The development of new radiopharmaceuticals goes along with preclinical studies assessing their
efficiency in tumor control as well as their toxicity on healthy tissues and comparing their effect
with conventional external radiotherapy using x-rays or β-emitting targeted radiotherapy. It is
thus necessary to determine the dose deposited in the sample (cells in the case of in vitro experi-
ments) to accurately quantify biological effects. Nevertheless, dosimetry of α-emitters is challeng-
ing even for in vitro experiments. In this case, absorbed dose is related to the proportion of decay
occurring close enough of the cells (because of the short range of α particles) and the cells dimen-
sions (determining the proportion of energy deposited). It is usually assumed that the distribution
of radionuclides in the culture medium is homogenous, which could have a significant impact on
dose calculation. In this study we measured the spatial distribution of α-emitting 212Pb coupled
to an anti-VCAM-1 antibody (212Pb-αVCAM-1) and its evolution over time in the context of in
vitro irradiations.
Methods. To determine the spatial distribution of 212Pb-αVCAM-1, two volumes of culture medium,
containing 15 kBq of 212Pb-α-VCAM-1 each, were poured into two test wells without cells. The
first well had a 2.5-µm-thick mylar-base and was placed above a 144 µm thick silicon detector. The
second well was a commercially available dish and was placed below an identical detector. With
these setups, experimental count rates and energy spectra of α-particles were measured during 20
hours. Experimental spectra were analyzed with Monte Carlo simulations. Experimental setups
were reproduced to simulate the α-energy spectra in the silicon detectors as a function of the de-
cay position in the culture medium. Simulated spectra were then used to deduce the radionuclide
spatial and temporal distribution from experimental spectra.
Results. Experimental count rates and energy spectra showed differences in measurements taken
at the top and the bottom of dishes and temporal variations that did not follow 212Pb decay. The
radionuclide spatial distribution was shown to be composed of a homogeneous distribution and
concentration gradients at the top and the bottom, which were subjected to temporal variations
caused by gravity and electrostatic attraction. The absorbed dose in cells calculated from this dis-
tribution was compared with the dose expected for a homogeneous and static distribution and
found to be 1.75 times higher. This discrepancy is significant and is an important issue regarding
the accuracy and the reliability of preclinical studies.
Conclusion. This work demonstrated that accurate dosimetry of α-emitters requires the exper-
imental determination of radionuclide spatial and temporal distribution. It highlighted that in
vitro assessments of TAT cannot only rely on injected activity and should benefit from adapted
dosimetry methods.
Funding: CNRS, CEA, Université de Caen-Normandie, MESR, Conseil Régional-Normandie and
the European Union-Fonds Européen de Développement Régional (FEDER), FRC, ANR-11-LABEX-
0018-01 ; ANR-10EQPX1401.
April 7, 2020 Page 37XVth Rencontres … / Rapport sur les contributions Radionuclide spatial distribution m … Summary Orateur: Dr FRELIN, Anne-Marie (GANIL) April 7, 2020 Page 38
XVth Rencontres … / Rapport sur les contributions Summary and conclusion
Contribution ID: 75 Type: not specified
Summary and conclusion
vendredi 2 août 2019 10:30 (1 heure)
Summary
Orateur: Prof. GROSSMANN, Martin (Paul Scherrer Institut)
April 7, 2020 Page 39XVth Rencontres … / Rapport sur les contributions PET and multimodality imaging pr …
Contribution ID: 76 Type: not specified
PET and multimodality imaging principles
samedi 27 juillet 2019 08:30 (1h 30m)
Summary
Orateur: Prof. VISVIKIS, Dimitris (INSERM)
April 7, 2020 Page 40XVth Rencontres … / Rapport sur les contributions History and physics of photon, ele …
Contribution ID: 78 Type: not specified
History and physics of photon, electron, neutron and
pion therapy
samedi 27 juillet 2019 10:15 (1h 30m)
Summary
Orateur: Prof. SIHVER, Lembit (TU Wien, Atominstitut)
April 7, 2020 Page 41XVth Rencontres … / Rapport sur les contributions Radiation Matter Interactions
Contribution ID: 80 Type: not specified
Radiation Matter Interactions
samedi 27 juillet 2019 13:00 (1h 30m)
This lectrures aims to give an overview of the radiation matter interactions. Charged particles and
neutral particles processes are described along with the main medical applications.
(In the slides everything in light grey can be skiped, it contains material for a deeper understand-
ing).
Summary
Orateur: Prof. BAN, Gilles (LPC Caen)
April 7, 2020 Page 42XVth Rencontres … / Rapport sur les contributions What is Medical Physics?
Contribution ID: 81 Type: not specified
What is Medical Physics?
samedi 27 juillet 2019 14:30 (1h 30m)
Summary
Orateur: Dr LE DU, Patrick
April 7, 2020 Page 43XVth Rencontres … / Rapport sur les contributions History and physics of ion beam t …
Contribution ID: 83 Type: not specified
History and physics of ion beam therapy
samedi 27 juillet 2019 16:15 (1 heure)
Summary
Orateur: Prof. SIHVER, Lembit (TU Wien, Atominstitut)
April 7, 2020 Page 44XVth Rencontres … / Rapport sur les contributions GATE lecture
Contribution ID: 85 Type: not specified
GATE lecture
dimanche 28 juillet 2019 08:30 (1h 30m)
Summary
Orateur: Dr CHAUVIN, Maxime (INSERM)
April 7, 2020 Page 45XVth Rencontres … / Rapport sur les contributions GATE exercise
Contribution ID: 86 Type: not specified
GATE exercise
dimanche 28 juillet 2019 10:15 (1h 30m)
Summary
Orateur: Dr CHAUVIN, Maxime (INSERM)
April 7, 2020 Page 46XVth Rencontres … / Rapport sur les contributions EasyPET exercise
Contribution ID: 87 Type: not specified
EasyPET exercise
dimanche 28 juillet 2019 13:00 (1h 30m)
EasyPET is a table-top experimental kit to demonstrate the principle of PET imaging. After an
introduction to the device and its components (scintillating crystals, silicon photomultipliers, co-
incidence electronics and reconstruction of PET images) we will explore the detector properties,
study detector response from a beta plus emitter (radioactive source) and acquire a PET image
Summary
Orateur: Dr GROSSMANN, Martin (Paul Scherrer Institut)
April 7, 2020 Page 47XVth Rencontres … / Rapport sur les contributions Radiotherapy / Organ motion lecture
Contribution ID: 88 Type: not specified
Radiotherapy / Organ motion lecture
dimanche 28 juillet 2019 14:30 (45 minutes)
Summary
Orateur: Dr ZHANG, Ye (PSI)
April 7, 2020 Page 48XVth Rencontres … / Rapport sur les contributions Image reconstruction exercise
Contribution ID: 89 Type: not specified
Image reconstruction exercise
dimanche 28 juillet 2019 15:30 (2 heures)
Summary
Orateur: Dr HOANG THI KIEU, Trang (HCMUS)
April 7, 2020 Page 49XVth Rencontres … / Rapport sur les contributions Opening Session
Contribution ID: 90 Type: not specified
Opening Session
lundi 29 juillet 2019 08:30 (35 minutes)
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