The choice is clear. Trying to lower very high triglycerides?* - Vascepa
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Trying to lower
very high triglycerides?*
The choice is clear.
Prescription power
Clinically proven
FDA-approved
Ask your doctor about VASCEPA®, the first and
only prescription EPA treatment.
Triglycerides are fats in the blood. Very high triglyceride levels are ≥500 mg/dL.
*
WHAT IS VASCEPA?
VASCEPA is a prescription medicine used along with a
low-fat and low-cholesterol diet to lower high levels of
triglycerides (fats) in adults.
What are triglycerides and how do they
differ from cholesterol?
It’s time to discover
Triglycerides, like cholesterol, are both naturally VASCEPA.
occurring fats in your blood. Although similar, they
are not the same. Cholesterol is important for your
cells and makes some hormones. Triglycerides store Pure power.
unused calories and give your body energy.
However, very high levels of cholesterol or Proven to work.
triglycerides may lead to serious health problems.1
1. NIH MedlinePlus Cholesterol 2018, NIH MedlinePlus Triglycerides Prescription VASCEPA, along with diet,
Test 2017.
is clinically proven to lower very high
triglycerides in adults by
APPROXIMATELY
4 MILLION AMERICANS
have very high triglycerides.
without raising bad
You may be working with your doctor cholesterol (LDL-C).*
and trying hard to lower your very
high triglycerides.
It can be hard work battling very high triglycerides.
You may have tried eating a healthier diet and
exercising more, but if your triglyceride levels
are still very high–it may be time to consider
prescription VASCEPA.
*
In MARINE trial, on average, along with diet
changes, adults with very high triglycerides
experienced a 33% reduction without raising
LDL-C vs. placebo. Individual results may vary.
WHAT IS VASCEPA? (continued)
• It is not known if VASCEPA changes your risk of • It is not known if VASCEPA prevents you from
having inflammation of your pancreas (pancreatitis). having a heart attack or stroke.
• It is not known if VASCEPA is safe and effective
in children.
2 3
VASCEPA looks different because it is different.
Most unproven COMMON Prescription
fish oil supplements FISH OIL EPA VASCEPA
contain DHA*, No DHA; and VASCEPA
an Omega-3, was shown not to
which can raise bad raise bad cholesterol
cholesterol (LDL-C). (LDL-C).†
Not FDA-approved FDA-approved
to treat medical and clinically proven
conditions, including to lower very high
very high triglycerides. triglycerides.
Daily dose: Daily dose:
It may take up to Two 1-gram capsules,
10-40 capsules a day twice a day.
to equal the EPA in a
No reported fishy taste
daily dose of VASCEPA.*
or fishy burps while
Reported to have taking 4 grams per day
fishy taste of VASCEPA in a
or cause fishy burps.* clinical trial.†
Prone to deterioration Proven stability*
Fishy smell suggests Demonstrated
chemical change and multi-year stability
may be covered up by an [preserves full effect].
added scent or flavor.
MARINE
†
trial, as compared
*
Data on file. with placebo.
Discover the
prescription power
of VASCEPA.
IMPORTANT SAFETY INFORMATION
WHO SHOULD NOT TAKE VASCEPA?
• Do not take VASCEPA if you are allergic to icosapent • If you have liver problems and are taking VASCEPA,
ethyl or any of the ingredients in VASCEPA. your doctor should do blood tests during treatment.
WHAT ARE THE POSSIBLE SIDE EFFECTS OF VASCEPA? • The most common side effect of VASCEPA is joint
• It is not known if people who are allergic to fish pain. Talk to your doctor for medical advice about
or shellfish are also allergic to VASCEPA. side effects.
4 5
VASCEPA (icosapent ethyl) Coverage and Savings.
is different from
The VASCEPA Savings Program.
Omega-3-acid ethyl esters.
VASCEPA is covered without restriction
This chart contains FDA-approved prescription product
for the majority of patients.
information related to patients with very high triglycerides
taking 4 grams per day. With the VASCEPA Savings Card, commercially
No head-to-head trials have been conducted between insured patients pay as little as $9 for 90 days.*
VASCEPA and other prescription Omega-3s.
Subject to eligibility. Restrictions apply.
VASCEPA1 Omega-3-acid
(icosapent ethyl) ethyl esters2-7
Clinically proven and
FDA-approved to lower very
high triglycerides1-2
Contains only one active
ingredient: p
rescription EPA1
Not shown to raise bad
cholesterol (LDL-C)1-2
This VASCEPA Savings Card is active and ready to use.
Doesn’t require additional Registration or activation is not required.
monitoring of bad cholesterol1 Present it to your pharmacist with your VASCEPA
prescription to start saving now.
No reported “burping, upset *
May not be used to obtain prescription drugs paid for in part by Federal or
stomach, or a change in sense State Healthcare Programs including Medicare, Medicaid, Medicare Advantage,
of taste”1-7 Medicare Part D, Tricare, and VA. Not for use by VT residents, VT licensed
medical professionals, patients under 18, where prohibited by law or patient’s
insurance plan, or where taxed or restricted. Maximum savings of $110
per month or $330 per 90 day supply. Eligible patients include those who
participate in commercial insurance, through a healthcare exchange, or pay
cash. Offer good through December 31, 2019.
Omega-3-acid ethyl esters should not be substituted
for VASCEPA. If your pharmacist suggests
switching, talk with your doctor first. IMPORTANT SAFETY INFORMATION (continued)
As with all drugs, you may experience a serious side
effect when taking VASCEPA.
1. VASCEPA [package insert]. Bedminster, NJ: Amarin Pharma, Inc; 2017.
2. Omega-3-acid ethyl esters Prescribing Information. GlaxoSmithKline; 2015.
You may report side effects by calling 1-855-VASCEPA
3. Omega-3-acid ethyl esters Prescribing Information. Amneal or the FDA at 1-800-FDA-1088.
Pharmaceuticals of New York LLC 2016.
4. Omega-3-acid ethyl esters Prescribing Information. Apotex Inc 2014. Tell your doctor if you take medicines that affect your
5. O mega-3-acid ethyl esters Prescribing Information. Par Pharmaceutical Inc 2017.
6. Omega-3-acid ethyl esters Prescribing Information. Strides Pharma Global blood clotting (anticoagulants or blood thinners).
Pte Ltd 2017.
7. Omega-3-acid ethyl esters Prescribing Information. Teva Pharmaceuticals Take VASCEPA capsules whole. Do not break, crush,
2016. dissolve, or chew VASCEPA capsules before swallowing.
For more information on VASCEPA, see the Patient
Information on pages 10-11 or call 1-855-VASCEPA
6 (1-855-827-2372). 7
It is important to take the 4-gram The VASCEPA Clear Path Program.
daily dose of VASCEPA. Periodically, you’ll receive helpful tips like delicious
healthy recipes, easy and effective exercises you can
To ensure you get the full benefit of VASCEPA, it’s
do at home, and news about VASCEPA.
important to take the FDA-approved 4-gram dose
each day as your doctor prescribes. It’s all in the VASCEPA Clear Path Program. Designed
to encourage you to partner with your doctor to
Available in two convenient sizes: support you on your journey.
Here’s a couple of Clear Path Tips
For the standard size, If you prefer the smaller to help lower very high triglycerides:
take two 1-gram size, take four of the
capsules twice a day 0.5-gram capsules
with food. twice a day with food. Tip
Simple Swaps.
Put a bowl of fruit and veggies
on the kitchen counter and
make a family pact to try to
reduce salty or sugary snacks
to 1-2x a week so you’re all in
it together!
Small Steps, Big Strides.
The next time you go
shopping or to work, try
parking your car in a farther
spot. A few extra steps here
and there can really add up.
VASCEPA Safety Information. (National Heart, Lung, and Blood Institute, What Can My Family and
VASCEPA has a safety profile similar to placebo. I Do To Encourage a Healthy Weight?)
The most common side effect reported by 2.3%
of patients on VASCEPA was joint pain compared
to 1% on a placebo. In a clinical study, no patients
taking 4 grams of VASCEPA per day reported For more easy, helpful tips, join the VASCEPA
fishy taste or fishy burps.* Clear Path Program on Vascepa.com.
*
MARINE trial, as compared with placebo.
8 9
PATIENT INFORMATION • If you miss a dose of VASCEPA, take it as soon as you
VASCEPA® (pronounced vas-EE-puh) remember. However, if you miss one day of VASCEPA,
(icosapent ethyl) Capsules do not double your dose when you take it.
WHAT IS VASCEPA? • Your doctor may start you on a diet that is low in saturated
VASCEPA is a prescription medicine used along with a low-fat fat, cholesterol, carbohydrates, and low in added sugars
and low-cholesterol diet to lower high levels of triglycerides before giving you VASCEPA. Stay on this diet while taking
(fats) in adults. VASCEPA.
• Your doctor may do blood tests to check your triglyceride
It is not known if VASCEPA changes your risk of having and other lipid levels while you take VASCEPA.
inflammation of your pancreas (pancreatitis).
WHAT ARE THE POSSIBLE SIDE EFFECTS OF VASCEPA?
It is not known if VASCEPA prevents you from having a heart If you have liver problems and are taking VASCEPA,
attack or stroke. your doctor should do blood tests during treatment.
It is not known if VASCEPA is safe and effective in children. The most common side effect of VASCEPA is joint pain.
Do not take VASCEPA if you are allergic to icosapent ethyl As with all drugs, you may experience a serious side effect
or any of the ingredients in VASCEPA. See the end of this when taking VASCEPA. Talk to your doctor if you have a
summary for a complete list of ingredients in VASCEPA. side effect that bothers you or does not go away.
Before taking VASCEPA, tell your doctor about all of your These are not all the possible side effects of VASCEPA.
medical conditions, including if you: Call your doctor for medical advice about side effects.
• have diabetes. You may report side effects to FDA at 1-800-FDA-1088.
• have a low thyroid problem (hypothyroidism).
• have a liver problem. HOW SHOULD I STORE VASCEPA?
• have a pancreas problem. • Store VASCEPA at room temperature between 68° to 77° F
• are allergic to fish or shellfish. It is not known if people who (20° to 25° C).
are allergic to fish or shellfish are also allergic to VASCEPA. • Safely throw away medicine that is out of date or no longer
• are pregnant, or planning to become pregnant. It is not needed.
known if VASCEPA will harm your unborn baby. Keep VASCEPA and all medicine out of the reach of children.
• are breastfeeding or plan to breastfeed. VASCEPA can pass General information about the safe and effective use of
into your milk, and may harm your baby. Talk to your doctor VASCEPA. Medicines are sometimes prescribed for purposes
about the best way to feed your baby if you take VASCEPA. other than those listed in Patient Information Leaflets. Do not
Tell your doctor about all the medicines you take, including use VASCEPA for a condition for which it was not prescribed.
prescription and over-the-counter medicines, vitamins, and Do not give VASCEPA to other people, even if they have the
dietary or herbal supplements. same symptoms you have. It may harm them. You can ask
VASCEPA can interact with certain other medicines that your pharmacist or healthcare provider for information about
you are taking. VASCEPA that is written for health professionals.
Especially tell your doctor if you take medicines that affect WHAT ARE THE INGREDIENTS IN VASCEPA?
your blood clotting (anticoagulants or blood thinners). Active Ingredient: icosapent ethyl
Inactive Ingredients: tocopherol, gelatin, glycerin,
HOW SHOULD I TAKE VASCEPA? maltitol, sorbitol, and purified water
• Take VASCEPA exactly as your doctor tells you to take it.
• Do not change your dose or stop taking VASCEPA without For more information, go to www.VASCEPA.com or
talking to your doctor. call 1-855-VASCEPA (1-855-827-2372).
• Do not take more capsules than what is prescribed by This patient information has been approved
your doctor. by the U.S. Food and Drug Administration.
-If you are prescribed the 0.5-gram capsules, you should
VASCEPA is a registered trademark of the Amarin group of companies.
not take more than 8 capsules each day.
© 2016 Amarin Pharma, Inc. Bedminster NJ, 07921 All rights reserved
-If you are prescribed the 1-gram capsules, you should
Distributed by: Amarin Pharma, Inc. Bedminster, NJ, USA
not take more than 4 capsules per day.
• Take VASCEPA capsules whole. Do not break, crush, Manufactured for: Amarin Pharmaceuticals Ireland Limited Dublin, Ireland
+1-855-VASCEPA (+1-855-827-2372) www.vascepa.com
dissolve, or chew VASCEPA capsules before swallowing.
PP00120K 2/2017
10 11Ask your doctor about the
VASCEPA difference.
• Power. The first and only prescription EPA treatment.
• Proven. Clinically proven.
• Prescription. FDA-approved.
Sign up for
The VASCEPA Clear Path Program.
Periodically, you’ll receive helpful tips like
delicious healthy recipes, easy and effective exercises
you can do at home, and news about VASCEPA.
Visit Vascepa.com
For more information on VASCEPA,
see the Patient Information on pages 10-11,
visit Vascepa.com, or call 1-855-VASCEPA (1-855-827-2372).
Special Savings. Details inside.
Trademarks are owned by their respective companies; VASCEPA, Amarin,
and VASCEPA/Amarin logos are registered trademarks of the Amarin group
of companies.
© 2019 Amarin Pharma, Inc. Bedminster, NJ, USA. All rights reserved.
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