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Engineer - AT THE FOREFRONT OF THE - School of Engineering and Applied ...
Engineer
  BUFFALO

            2021

AT THE
FOREFRONT
OF THE
PANDEMIC
Engineer - AT THE FOREFRONT OF THE - School of Engineering and Applied ...
MESSAGE FROM THE DEAN
                                                                                               BUFFALO

                                                                                                                                        2021
                                                                                      Buffalo Engineer is published by the UB School of
                                                                                      Engineering and Applied Sciences to showcase the
                                                                                      excellence of our faculty, staff, alumni and students.
                                                   Kemper Lewis, PhD, MBA
                                                   Dean, School of Engineering and    School Leadership
                                                   Applied Sciences                    Kemper Lewis, Dean
                                                                                       Rajan Batta, Associate Dean for Faculty Affairs
                                                                                       and Diversity
                                                                                       Shambhu Upadhyaya, Associate Dean for
                                                                                       Research and Graduate Education
                                                                                       Jeffrey Errington, Associate Dean for
                                                                                       Undergraduate Education
                                                                                       Christine Human, Associate Dean for
                                                                                       Accreditation and Student Affairs
                                                          Photo: Onion Studio, Inc.
                                                                                      Department Chairs

Dear Friends of the School of                                                          Albert Titus, Biomedical Engineering
                                                                                       Mark Swihart, Chemical and Biological Engineering
Engineering and Applied Sciences,                                                      Joseph Atkinson, Civil, Structural and Environmental
                                                                                       Engineering
    The past year has brought significant challenges for each of us                    Chunming Qiao, Computer Science and Engineering
individually and as a community. I have heard many stories from our                    Jonathan Bird, Electrical Engineering
                                                                                       Carl Lund, Engineering Education
students, staff, faculty and alumni, collectively marked by a wide range of
                                                                                       Victor Paquet, Industrial and Systems Engineering
emotions including grief, anger, frustration, gratitude, encouragement                 Krishna Rajan, Materials Design and Innovation
and hope. These conversations have also revealed the resilience, creativity,           Francine Battaglia, Mechanical and Aerospace
collegiality, brilliance and selflessness of our community.                            Engineering
                                                                                      Engineering Alumni Association Officers
    In this year’s issue of Buffalo Engineer magazine, you will read about
                                                                                       Jordan Walbesser, President
how we have come together during these times of uncertainty. Right from                JD ‘10, BS ‘07 CSE
the start of the pandemic, our faculty quickly pivoted their expertise to ease         Kurt Bessel, Immediate Past President
                                                                                       MS ‘08, BS ‘07 ME, BA German ‘07
the shortage of PPE, develop vaccines and health monitoring equipment, and
                                                                                       Luke Adams, Vice President
partner with community organizations to help keep the public safe (page 14).           BS ‘08 MAE
    The UB Engineering and Applied Sciences Alumni Association remained                Tim van Oss, Secretary
                                                                                       MS ’16, BS ‘14 CSEE
active and developed creative ways to continue growing and deepening their
                                                                                       Francis Mahaney, Treasurer
interactions with students (page 18).                                                  BS ‘12 CSEE
    Other alums pivoted their businesses or started new ones to address                Kristen Murphy, SEAS Liaison
                                                                                       BA’96
pandemic-related needs. On page 26 you will read about a local distillery
                                                                                      Editor
that provided free hand sanitizer to the community, and on page 28, a new              Jane Stoyle Welch
wellness app for sleep and focus.                                                     Contributing Writers
    And, in response to racial unrest, we formed a working group to create             Michael Andrei, Nicole Capozziello, Sarah D’Iorio,
                                                                                       Peter Murphy, Cory Nealon, Tracy Puckett
opportunities to address deficiencies in critical areas so that we can grow,
                                                                                      Cover Illustration
improve, and increase our success, significance and impact. Our efforts
                                                                                       Peter Reiling
related to racial equity are now known as SEAS for JEDI (Justice, Equity,
                                                                                      Design
Diversity, and Inclusion – see back cover).
                                                                                       Jason Yates
    As we approach the one-year mark since the coronavirus changed all of             Photography
our lives, we are looking ahead to a brighter future. But challenges remain. In        Maximilian Kapitonoff, Meredith Forrest Kulwicki,
                                                                                       Douglas Levere, Onion Studio, Inc.
the coming weeks, you will hear about our Student Emergency Campaign to
help our students in need.
                                                                                      Support Our School
    I am extremely proud of our SEAS community, which has risen to the
                                                                                      Your philanthropic support helps to fund a variety
challenges we face with integrity and innovation, and thank you for your              of student programs. Please visit buffalo.edu/
                                                                                      campaign/seas to make your contribution. Your
continued support.                                                                    participation at any level is appreciated.
    Together, let’s lead, and in our leading, bring positive change.                  Address Changes
                                                                                      UB Alumni can update their address
                                                                                      through UB Connect: ub-connect.com
                                                                                      All others should email seascomm@buffalo.edu
                                                                                      or clip the address label and return it with the
                                                                                      correct address to: Buffalo Engineer, School of
                                                                                      Engineering and Applied Sciences, University
    Kemper Lewis, PhD, MBA                                                            at Buffalo, 438 Bell Hall, Buffalo, NY 14260.
    Dean, School of Engineering and Applied Sciences
Engineer - AT THE FOREFRONT OF THE - School of Engineering and Applied ...
CONTENTS

At the Forefront
of the Pandemic
From vaccine development to mental
health apps, learn how our faculty,
staff and students are pushing
ahead to combat COVID-19.

                                                                                                       2   NEWS BRIEFS
                                                                                                           New research announcements, research
                                                                                                           results, exciting discoveries, and more.

                                                                                                            6       RESEARCH HIGHLIGHTS
                                                                                                            10      SCHOOL NEWS
                                                                                                            12      10 QUESTIONS WITH THE DEAN

                                                                                   14                       13      ENGINEERING PARTNERS

                                                                                                      22   STUDENTS
                                                                                                           Using 3D printing to make prosthetic hands,
                                                                                                           MDI graduates first PhDs, and more.

                                                                                                      26   ALUMNI
                                                                                                           Distillery turns spirits into hand sanitizer for
                                                                                                           the community, industrial engineer creates

         18
                                                                                                           a wellness app, and more.

                                                                                                      30   CLASS NOTES
                                          Making an
                                                                                                           Learn about the achievements and
                                                                                                           accomplishments of your classmates.

                                  Impact on Students
                           The UB Engineering and Applied Sciences Alumni Association                 32   LAST WORD
                                                                                                           Fighting the coronavirus pandemic
                                      is working to improve school spaces and create more
                                                                                                           with wearable tech.
                                                    opportunities to connect with students.

       Facebook                                               YouTube
       @ubseas                                                UBengineering

                                                                                                                Some photos that appear in this magazine
       Twitter                                                LinkedIn
       @UBengineering                                         University at Buffalo Engineering and             were taken prior to the COVID-19 pandemic
                                                              Applied Sciences                                  and therefore may not accurately reflect
                                                                                                                current operations or adherence to UB’s
       Instagram                                              Sign up for our eNewsletter                       Health and Safety Guidelines.
       @ubengineering                                         engineering.buffalo.edu/news
Engineer - AT THE FOREFRONT OF THE - School of Engineering and Applied ...
NEWS BRIEFS

    The 24,000-square-foot research facility, SOAR (Structure for
    Outdoor Autonomy Research), is believed to be the third-largest
    outdoor, enclosed drone-testing facility in the nation.

                                                                                                                                          Photo: Douglas Levere

UB BUILDS MASSIVE
                                                                          Chase Murray, assistant professor of industrial and systems
                                                                      engineering, secured a $393,000 grant from the Office of Naval Research’s

OUTDOOR DRONE
                                                                      Defense University Research Instrumentation Program to support the
                                                                      facility’s construction. At slightly more than half an acre and 86 feet tall,

TESTING FACILITY
                                                                      SOAR is believed to be the third-largest outdoor, enclosed drone-testing
                                                                      facility in the nation.
                                                                          Because it is enclosed, and thus considered an indoor flight facility,
                                                                      researchers will not be subject to Federal Aviation Administration
                                                                      rules when testing UAVs. Researchers will use the facility to explore
                                                                      unmanned vehicle research focused on drone deployment optimization,
                                                                                autonomous vehicle fleet management, and prototype testing
    A new outdoor research facility, dubbed SOAR (Structure
                                                                                research to support applications in agriculture, homeland
for Outdoor Autonomy Research), is nearing completion on
                                                                                security, product service delivery, wildfire monitoring, and
UB’s North Campus.
                                                                                bridge/building inspections.
    The enclosed netted complex will allow faculty, students
                                                                                    The facility will also be a resource for undergraduate and
and industry partners to conduct experiments on uncrewed
                                                                                graduate students who study robotics and computer vision.
aerial vehicles (UAVs), which are more commonly known as
                                                                                Additionally, it will benefit Western New York companies
unmanned aerial vehicles or drones.
                                                                                interested in using the complex to test UAV hardware. For more
                                                                                information, contact Chase Murray at cmurray3@buffalo.edu.

2     |   BUFFALO ENGINEER 2021
Engineer - AT THE FOREFRONT OF THE - School of Engineering and Applied ...
NEWS BRIEFS
PHOTOACOUSTIC TOMOGRAPHY
ENHANCES BIOMETRIC SECURITY
                                                                    Researchers
                                                                    developed a new
                                                                    biometric approach
                                                                    that uses 3D images
                                                                    of finger veins.
                                                                                                    NEW CENTER TO FOCUS
                                                                    Shown are finger
                                                                    vessel images from six
                                                                                                    ON CELL, GENE AND
                                                                    different subjects, with
                                                                    colors that represent
                                                                                                    TISSUE ENGINEERING
                                                                    different depths.
                                                                                                    Stem cell expert and SUNY
    Biometric authentication uses anatomical features such                                          Distinguished Professor
as fingerprints or facial features to verify a person’s identity.                                   Stelios Andreadis named
What’s next for this field? The veins in your fingers, according
to Jun Xia, an associate professor in the Department of
                                                                                                    inaugural director
                                                                                                        A team of researchers in chemical, biological
Biomedical Engineering. He led a study that described how 3D
                                                                                                    and biomedical engineering have joined forces to
images of finger veins could boost digital security, which was
                                                                                                    develop innovative technologies for regenerative
published in Applied Optics (Vol. 59, Issue 2).
                                                                                                    medicine and educate future leaders in the field.
                                                                                                        Funded by the UB Provost, the new Center
                                                                                                    for Cell, Gene and Tissue
PAPER-THIN TRANSISTORS                                                                              Engineering (CGTE) will be
                                                                                                    led by SUNY Distinguished
                                                                    A gallium oxide-                Professor Stelios Andreadis.
                                                                    based transistor
                                                                                                        Andreadis is an expert in
                                                                    being developed
                                                                    by UB researchers               stem cells, tissue engineering
                                                                    could help improve              and regenerative medicine,
                                                                    how far electric
                                                                                                    and is the director of UB’s
                                                                    cars, airplanes and
                                                                    locomotives can travel.         Stem Cells in Regenerative Medicine (SCiRM)
                                                                                                    Training Program, a joint initiative between the
                                                                                                    UB School of Engineering and Applied Sciences,
Transistors crafted from gallium oxide could lead to smaller
                                                                                                    Jacobs School of Medicine and Biomedical Sciences
systems for controlling and converting electric
                                                                                                    and Roswell Park Comprehensive Cancer Center
power in electric cars, locomotives and airplanes. A study
                                                                                                    Graduate Division and funded by the New York
led by electrical engineer Uttam Singisetti found that paper-
                                                                                                    State Stem Cell Science Board (NYSTEM).
thin electronic switches can handle 8,000 volts. Advances
                                                                                                        The Center will initially focus on several areas
in transistor technology could increase the distance that
                                                                                                    of core faculty expertise, including stem cell
electronic vehicles can travel. The study was published in IEEE
                                                                                                    engineering, tissue engineering and regeneration;
Electron Device Letters (Volume: 41, Issue: 6, June 2020).
                                                                                                    biomaterials; cell and tissue biomechanics; gene,
                                                                                                    protein and drug delivery (including novel vectors,
                                                                                                    vaccines and CRISPR technologies), novel imaging
ASCE RECOGNIZES CIVIL                                                                               technologies; high-throughput data acquisition

AND ENVIRONMENTAL                                                                                   technologies; BioMEMS; and omics (genomics,
                                                                                                    proteomics, glycomics) and associated systems,
ENGINEERING PROGRAMS                                                                                computational and big data engineering.
                                                                                                        Core faculty are Sriram Neelamegham, Natesh
    The Department of Civil, Structural and Environmental Engineering earned
                                                                                                    Parashurama, Sheldon Park and Blaine Pfeifer,
the 2020 Walter Lefevre Award from the American Society of Civil Engineers
                                                                                                    from the Department of Chemical and Biological
in recognition of its “outstanding program promoting licensure, ethics and
                                                                                                    Engineering, and B. Rita Alevriadou, Jonathan
professionalism.”
                                                                                                    Lovell, Yun Wu and Ruogang Zhao, from the
    In order to earn this award, CSEE was assessed on a variety of criteria, including
                                                                                                    Department of Biomedical Engineering.
more than 60% of students taking the Fundamentals of Engineering (FE) exam, number
of faculty licensed in a U.S. jurisdiction, how the department addresses licensure, ethics
and professionalism through its curriculum and activities, and other attributes.

                                                                                               UB School of Engineering and Applied Sciences           |   3
Engineer - AT THE FOREFRONT OF THE - School of Engineering and Applied ...
NEWS BRIEFS

                                                      MOVING FORWARD TOGETHER TOWARDS
                                                      A CLEANER, SAFER FUTURE
                                                          The Collaboratory for a Regenerative Economy (CoRE) is a unique research, education and
                                                      civic entrepreneurship initiative that links materials design with manufacturing technologies in
                                                      coordination with the needs of industry and front-line communities. Formed in 2017 and led by
                                                      Krishna Rajan, SUNY Distinguished Professor, Erich Bloch Chair and Empire Innovation Professor
                                                      in the Department of Materials Design and Innovation, CoRE was renewed at $3 million for a second
                                                      three years. CoRE’s innovative collaborations and data-driven tools enable business, government,
                                                      and nonprofit leaders to identify and select inherently safer chemicals and sustainable materials for
                                                      a healthier renewable energy economy. Partners include Niagara Share, located in Buffalo, and Clean
                                                      Production Action, located in Boston.

UB RESEARCHERS DEVELOP
NEW MOLECULAR
FERROELECTRIC
METAMATERIALS

                                                                                                 3D-printed molecular ferroelectric metamaterial made of
                                                                                                 imidazolium perchlorate.

                                                                                        The team, led by Shenqiang Ren, Department of Mechanical and

    A team of engineers has reported the discovery of a new 3D-printed              Aerospace Engineering and part of UB’s RENEW Institute, also includes

molecular ferroelectric metamaterial. The new material could benefit                Chi Zhou, Department of Industrial and Systems Engineering; Mostafa

everything from acoustic blankets for aircraft soundproofing to shock               Nouh, Department of Mechanical and Aerospace Engineering; and

absorbers and elastic cloaks that shield sensitive electronic systems from          Jeffrey Grossman, Department of Materials Science and Engineering,

external mechanical disturbances.                                                   Massachusetts Institute of Technology.

    The advancement, published in the Proceedings of the National                       They devised a plan to 3D print a scaffold-supported ferroelectric

Academy of Sciences, is a step toward making these lab-created materials            crystalline lattice made of imidazolium perchlorate. The unique design

more affordable and adaptable to countless multifunctional technologies.            of the lattice enables it to self-correct any deviations from the design

    A metamaterial is any material engineered to have a property that               while the material is still being printed. Also, the material’s stiffness

is not found in naturally occurring materials. Ferroelectricity relates to          — how much it resists deformation — is reprogrammable, which, in

crystalline substances that have spontaneous electric polarization that’s           turn, allows researchers to “tune” the material to filter out different

reversible by an electric field.                                                    subwavelength frequencies.

    The new study uses the latest advancements in computing, additive                   The work was partially funded by the U.S. Army Research Office.

manufacturing, materials design, acoustics and other fields to produce              The Department of Energy, National Science Foundation, and UB’s

ferroelectric metamaterials that are cost effective and easily adaptable to         New York State Center of Excellence in Materials Informatics provided

electronic and mechanical devices.                                                  additional funding.

4     |   BUFFALO ENGINEER 2021
Engineer - AT THE FOREFRONT OF THE - School of Engineering and Applied ...
TCIE DRIVES SUNY EFFORTS
TO PREPARE CLEAN ENERGY
WORKFORCE
    Historically, State University of New York schools have
largely operated in siloes in regard to renewable energy
education. But the scenario is changing, thanks to a SUNY
initiative and an extra push from the UB Center for Industrial
Effectiveness (TCIE).
    Communications between 10 institutions — from
community colleges to research universities — is widening
and collaborations are mounting, resulting in new online clean
energy courses and a website highlighting SUNY’s energy
                                                                    Photo: Onion Studio, Inc.
education pathways.
    The group’s formation began with Gov. Andrew M.                         A cornerstone of WiSE is the annual fall Early Move-In Program, which is
Cuomo’s Climate Jobs NY initiative. Nearly a dozen SUNY                     integral to their goal of supporting students — even before classes start. This
                                                                            program invites incoming fresh women to settle into campus early and then
campuses received a two-year Performance Improvement                        connect with their peers, network with faculty members, and participate in
Fund grant to implement clean energy workforce proposals in                 team-building activities.
support of New York’s climate change efforts.
    Performance Improvement Fund recipients are required
to attend a biannual Community of Practice meeting specific to
                                                                            LOCAL COMPANIES
their specialty area. The intention is to establish mutual goals,           MAKE ‘WiSE’ INVESTMENT
foster shared resources and best practices, and work toward
                                                                                 Three local companies are doing their part to narrow the gender gap in
collective outcomes.
                                                                            science and engineering. M&T Bank and Verizon Media join Linde (formerly
    The first session sparked murmurs of “I’m working on
                                                                            Praxair) in sponsoring UB’s Women in Science and Engineering program,
something similar. Why aren’t we talking?” TCIE took the lead
                                                                            known as WiSE.
in continuing the conversation beyond SUNY’s meetings by
                                                                                 Their support will enable WiSE to expand programming and provide
hosting monthly calls and organizing campus visits to view
                                                                            deeper support to female students in STEM than ever before.
labs and equipment.
                                                                                 “The heart of WiSE is fostering a sense of belonging,” says Chelsea
    “It’s great to be working together instead of just reporting
                                                                            Montrois, WiSE program coordinator. “And with this extended base of
out to each other,” says Jennifer Flagg, TCIE project director.
                                                                            support, we are so grateful that we can keep that going — and grow the reach
    For example, TCIE has leveraged the group to create
                                                                            and impact of WiSE even more.”
online courses that are available on Coursera. These include
                                                                                 The partnerships with Linde, Verizon Media and M&T Bank will
converting SUNY Erie solar photovoltaic technology curricula
                                                                            build up professional development programming, strengthening the bridge
into a three-part series on Solar Energy for Engineers,
                                                                            to industry for female students. Company representatives serve on the
Architects and Code Inspectors. The center also devised
                                                                            WiSE Faculty and Corporate Partner Steering Committee, which supports
Renewable Energy: Fundamentals and Job Opportunities, in
                                                                            both big picture planning and the delivery of programs. In addition, students
conjunction with experts from Alfred State College, SUNY
                                                                            are exposed to opportunities at companies with a demonstrated commitment
Buffalo State, SUNY Canton, SUNY Erie, Farmingdale State
                                                                            to diversity.
College and SUNY Polytechnic Institute.
                                                                                 WiSE hosts over 40 events a year to engage, educate and build
                                                                            community, from their alumni-student dinners, to study groups, to the WiSE
Engineering Technology Professor Ilya Grinberg (far right)                  Coffee and Conversation series, where students engage in a discussion led by
in SUNY Buffalo State’s Smart Grid Laboratory. From left are
                                                                            a female faculty member or industry professional over coffee and donuts.
Timothy Leyh of TCIE, John Williams of Alfred State College,
and Jennifer Flagg and Gary Simon of TCIE.                                       These activities give students a much-needed break — and they bring
                                                                            them together with other women in STEM, whether they’re fellow students,
                                                                            faculty and staff, alumni or engaged members of sponsor organizations.
                                                                                 Future goals include using or building a system that tracks WiSE
                                                                            students to measure the program’s success and illuminates growth
                                                                            opportunities, and identifying a permanent “home” on campus where
                                                                            WiSE students can study, collaborate, and seek support from WiSE staff.

                                                                                                UB School of Engineering and Applied Sciences          |   5
Engineer - AT THE FOREFRONT OF THE - School of Engineering and Applied ...
RESEARCH

UB AWARDED $8.5 MILLION TO IMPROVE
HYBRID SPACE ROCKETS, ADVANCE EXASCALE
COMPUTING TECHNOLOGIES

                                                                      Slab motor experiment showing the burning of paraffin wax fuel used in hybrid rockets.

                                   Paul DesJardin is leading a team of                     “This award puts UB students at the forefront of scholarly activity
                               researchers to study hybrid rockets, a                  in an incredibly exciting field that’s of great interest to NASA and other
                              technology that could provide a safer and less           federal agencies, as well as private aerospace companies like SpaceX,”
                             expensive way to explore outer space compared             says DesJardin, who added that the research team will also work with
                          to conventional rockets. The $8.5 million U.S.               doctoral students in UB’s Computational and Data Enabled Science and
                    Department of Energy award also enabled UB to establish            Engineering program.
the Center for Hybrid Rocket Exascale Simulation Technology (CHREST).                      In addition to DesJardin, UB investigators include Varun Chandola
    The award provides the resources to explore how hybrid rockets — a                 and Matthew Knepley, both associate professors in the Department of
nearly 100-year-old concept that’s getting a fresh look thanks to advancements         Computer Science and Engineering; James Chen, associate professor
in computing power and artificial intelligence — can be used to launch                 in the Department of Mechanical and Aerospace Engineering; Mark
satellites into space using common fuels like candle wax and kerosene.                 Swihart, UB Distinguished Professor and chair of the Department of
    “Our mission is to improve our understanding of how these rocket                   Chemical and Biological Engineering; Matthew Jones, interim director
systems work and to help optimize their performance,” says Paul DesJardin, a           and lead computational scientist at the UB Center for Computational
professor of mechanical and aerospace engineering and CHREST director.                 Research; and Letitia Thomas, assistant dean for diversity in the School
    UB will use the bulk of the funds to acquire extremely powerful                    of Engineering and Applied Sciences. Abani Patra, Stern Family Professor
computers, which the team will use to simulate previously developed hybrid             of Computer Science at Tufts University, is also an investigator.
rockets, as well as future theoretical rockets. The team will also develop                 The team will work with an advisory board of scientists from
machine learning algorithms that offer insight into how to better design               Lawrence Livermore National Laboratory, Sandia National Laboratories
hybrid rockets.                                                                        and the Los Alamos National Laboratory.
    Potential future uses of hybrid rockets include launching satellites,                  CHREST is one of nine new Predictive Science Academic Alliance
especially nanosatellites, into space from Earth. Such systems also                                 Program III Centers selected by the energy department’s
could be very useful in situations where high thrust is required                                          National Nuclear Security Administration (NNSA).
to lift heavy payloads loads into space from planetary                                                       The awards support science-based modeling
surfaces, such as NASA’s planned Mars Ascent mission.                                                           and simulation and exascale computing
    Another component of the grant involves educating                                                            technologies. The nine centers are funded by
UB students about hybrid technology. A portion of                                                                  NNSA’s Advanced Simulation and Computing
the funds will support a team of undergraduates who                                                                program, which engages the U.S. academic
compete in the annual Spaceport America Cup, the                                                                   community in advancing science-based
world’s largest intercollegiate rocket engineering                                                                 modeling and simulation technologies.
conference and competition.
                                                                                                                                                  by Cory Nealon

                                                                                                          The grant will support Students for the
                                                                                                          Exploration and Development of Space (SEDS),
                                                                                                          a UB student club that builds rockets like these.

6     |   BUFFALO ENGINEER 2021
Engineer - AT THE FOREFRONT OF THE - School of Engineering and Applied ...
AIR FORCE YOUNG INVESTIGATOR AWARD TO ENABLE
UNDERSTANDING HOW AIR FLOWS AROUND SMALL-SCALE DRONES
                                Frank Lagor, an assistant professor in the          The objective of the Young Investigator Program is to foster creative basic
                               Department of Mechanical and Aerospace           research in science and engineering, enhance early career development of
                                Engineering, is one of 36 scientists around     outstanding young investigators, and increase opportunities for the young
                                the country to receive funding from the         investigators to recognize the Air Force mission and related challenges in
                                competitive U.S. Air Force Young Investigator   science and engineering. It is open to United States citizens and/or permanent
                               Program.                                         residents who are scientists and engineers at U.S. research institutions who
                                   Lagor will use the $450,000 award to study   received PhD or equivalent degrees in the last seven years and show exceptional
                         the aerodynamics of small uncrewed aerial vehicles     ability and promise for conducting basic research of military interests.
(UAVs), more commonly known as drones.
    Small-scale drone use is becoming increasingly common, for example,                                                  INFERRED, 3D FLOW
                                                                                                                          CHARACTERISTICS
in package delivery, emergency response, and defense reconnaissance,
                                                                                                                                         SHEAR LAYER
with more applications emerging every day. However, in order to expand             LOCAL,
                                                                                2D ESTIMATE
their use, a better understanding of how the air flow patterns over their
wings affect lift is needed.
                                                                                                                    VORTEX FILAMENT
    Entitled “Towards Real-Time, 3D Coherent Structure Estimation for                                                                                     LOCAL,
                                                                                                                                                       2D ESTIMATE
Flow Over Finite Wings,” the project seeks to improve the fundamental
understanding of data-driven estimation of flow fields, as well as optimal
sensor placement to visualize the flow.
    The Young Investigator Program award is funded by the U.S. Air Force
Office of Scientific Research (AFOSR) in association with the Unsteady                                                                                 SENSOR ARRAY 2

Aerodynamics and Turbulent Flows Program. It will provide funding for
two graduate research assistants, and also benefits an ongoing research                       SENSOR ARRAY 1
collaboration between Lagor and researchers at the Air Force Research
Laboratory in Dayton, Ohio.                                                     Conceptual image of the flow sensing to estimate airflow features over a wing.

             #
                 33
                                                                                                                                                   9
                                                           $82                                   253
                                                         MILLION

     No. 33 public engineering
                                                 Research expenditures total            253 full-time faculty
   school, according to U.S. News                                                                                                     9 academic departments
                                                    $82 million annually               members and growing
      and World Report in 2021

                                          SCHOOL OF ENGINEERING AND APPLIED SCIENCES

                                        BY THE NUMBERS
        1,975

                           5,110                              2,123
                                                                                        67 COUNTRIES                                    ACCREDITED
    Our Fall 2020 student body                   2,123 degrees awarded in the          A global community with                          10 ABET-accredited
 consists of 1,975 graduate students               2019-2020 academic year            students from 67 countries                      undergraduate programs
     and 5,110 undergraduates                                                           and 33 different states

                                                                                                     UB School of Engineering and Applied Sciences             |   7
Engineer - AT THE FOREFRONT OF THE - School of Engineering and Applied ...
RESEARCH ON THE RISE
TEN WORLD-CHANGING NEW PROJECTS

                  UB is part of an $8.2 million U.S. Department of                       Chemical engineer Paschalis Alexandridis is leading a
                  Transportation project to help vulnerable populations                  UB research team to develop processing technologies that
                  with transportation issues. The UB team is led by civil                will make discarded plastic easier to reuse. The project
              engineer Adel Sadek, and the project focuses on improving              focuses on the development of a novel set of tools such as a robotic
              transportation options for people with disabilities, low-income        system that relies on machine learning and other technologies
              neighborhoods and older adults. Victor Paquet and Chunming             to autonomously improve its ability to sort plastics, as well as
              Qiao are collaborating on the project, which is led by Virginia-       environmentally responsible solvents and new chemistries that
              based ICF International.                                               break down plastics to make them easier to reuse. It is supported
                                                                                     by a four-year, $2 million grant from the National Science
                  Minghui Zheng, Department of Mechanical and Aerospace              Foundation’s Emerging Frontiers in Research and Innovation
                  Engineering, is the lead investigator on a $3 million NSF-         program. SEAS-affiliated team members include Amit Goyal,
                  funded project that seeks to advance effective human-              Thomas Thundat, Marina Tsianou, John Atkinson and Karthik Dantu.
              robot collaboration to reduce electronics remanufacturing
              costs and improve operator safety. The research will focus on              Industrial engineer Lora Cavuoto is partnering with colleagues
              electronic waste including used computers and mobile devices.              at Rensselaer Polytechnic Institute on a project that combines
              Civil engineer Xiao Liang is a co-PI on the project.                       neuroimaging, neuromodulation, and artificial intelligence
                                                                                     to better understand and measure surgical skill acquisition —
                   Chemical engineer Stelios Andreadis is leading a $2 million       and then determine if that mastery can be accelerated. The $2.2
                  grant from the National Institute of Aging to investigate the      million project is funded by the U.S. Army Medical Research and
                  regenerative capacity of aged muscles. The work may have           Development Command of the U.S. Department of Defense.
              significant impact in regenerative medicine and the quality of
              life of elderly patients. Co-PIs include faculty from UB’s Jacobs          Civil engineer Negar Elhami Khorasani is part of a multi-
              School of Medicine and Biomedical Sciences and the School of               institutional group of researchers who are working together
              Public Health and Health Professions.                                      to better understand and help prevent deadly wildfires.
                                                                                     Elhami-Khorasani is studying how fire spreads, considering
                  Biomedical engineer Xiaoliang Zhang is leading a team              uncertainties such as landscape, vegetation and environmental
                  of researchers from UB, UC Berkeley, Stanford University,          factors. Led by the University of Nevada, Reno, the project is part
                  University of Minnesota, Cleveland Clinic and GE Global            of a five-year, $2 million grant from NSF’s Leading Engineering for
              Research to develop new MRI tools. The comprehensive                   America’s Prosperity, Health and Infrastructure program.
              magnetic resonance imaging tool will be able to detect damage
              to connective tissues, such as ligaments, tendons and bone. The            Electrical engineer Qiaoqiang Gan is leading a team
              $3.7 million project is funded by the National Institutes of Health.       of researchers to develop a portable solar still —a sun-
                                                                                         powered water purifier that could provide drinking
                  David Doermann and Junsong Yuan, of the Department                 water in resource-scarce environments. The U.S. Army
                  of Computer Science and Engineering, are leading a                 Engineer Research and Development Center’s Cold Regions
                  $1.4 million DARPA project to detect and characterize              Research and Engineering Laboratory is funding the project
              fraudulent multimedia assets based on an automatic analysis            with a $1.4 million grant.
              of communicative intent. UB’s expertise in text analysis, video
              analytics, and information fusion will lead to new tools to                Environmental engineer Ian Bradley and his research
              combat the widespread onslaught of disinformation campaigns.               group are collaborating on a $2 million project funded by
                                                                                         the Department of Energy that will study the use of algae to
                                                                                     purify wastewater while simultaneously producing biomass for
                                                                                     fuel production. The project is led by the University of Illinois
                                                                                     Urbana-Champaign.

8   |   BUFFALO ENGINEER 2021
NSF CAREER AWARD FOCUSED ON
MAKING NANOELECTRONIC
DEVICES MORE
ENERGY EFFICIENT
    Electrical engineer Huamin Li is investigating a novel
transistor concept that can switch speed faster and use less
                                                                  EIGHTEEN NEW FACULTY
energy. The project is funded by a CAREER award from the          JOIN THE SCHOOL
National Science Foundation.
    Li’s project “Toward sub-60-mV/decade steep transistors
                                                                  OF ENGINEERING AND
using Dirac-source carrier injection and high-mobility 2D         APPLIED SCIENCES
monochalcogenides” is important because it seeks to find an       The School of Engineering and Applied Sciences welcomed
innovative solution to address the need for energy-efficient      18 new faculty members this year. These faculty represent a
nanoelectronic devices. It also explores the untapped potential   diverse set of research and educational expertise that will help
of emerging two-dimensional source and channel materials          the school and its departments achieve even greater levels of
such as graphene, and represents a major breakthrough in          excellence. The new faculty are:
quantum science and technology for extending Moore’s law
well into the quantum era.                                            Chemical and Biological Engineering
    Such technologies are of great interest, as they hold              – Miao Yu, SUNY Empire Innovation Professor
promise for overcoming limitations that may prevent further            – Ashlee Ford Versypt, Associate Professor
miniaturization of conventional transistors.                           – Viviana Monje-Galvan, Assistant Professor
    Li’s team will combine theoretical research with
experiments to learn about the properties of the 2D materials         Civil, Structural and Environmental Engineering
and use them to build a prototypical transistor.                       – Yinyin Ye, Assistant Professor
    With the support of his CAREER award, Li will also
participate in existing programs and develop new activities           Computer Science and Engineering
that seek to inspire the next generation of students to pursue         – Siwei Lyu, SUNY Empire Innovation Professor
careers in engineering. This includes working with UB and              – Nalini Ratha, SUNY Empire Innovation Professor
community partners to create educational activities that focus         – Hongxin Hu, Associate Professor
on nanoscience and nanotechnology. The project is funded at            – Xianghang (Scott) Mi, Assistant Professor
$500,000 for five years.                                               – Ziming Zhao, Assistant Professor
    The NSF CAREER Award is given to outstanding scientists            – Nasrin Akhter, Assistant Professor of Teaching
who exemplify the role of teacher-scholars through research,
education, and the integration of education and research.             Electrical Engineering
                                                                       – Jian-Ping (Jim) Zheng, SUNY Empire Innovation Professor

                                                                      Engineering Education
                                                                       – Matilde Sanchez-Pena, Assistant Professor
                                                                       – Cory Schimpf, Assistant Professor
                                                                       – Alice Nightengale, Assistant Professor of Teaching

                                                                      Industrial and Systems Engineering
                                                                       – Cecilia Martinez Leon, Associate Professor of Teaching

                                                                      Mechanical and Aerospace Engineering
                                                                       – Jiaoyan Li, Assistant Professor
                                                                       – Jun Liu, Assistant Professor
                                                                       – Ryan St. Pierre, Assistant Professor

                                                                             UB School of Engineering and Applied Sciences           |   9
SCHOOL NEWS

Titus                         Ying                            Alexandridis                     Goyal                       Hachmann                        Lin

Neelamegham                   Thundat                         Anastasopoulos                   Bruneau                     Elhami Khorasani                Xu

Yuan                           Mitin                          Oh                               Batta                       Bisantz                         Casucci

Cavuoto                       Zhuang                          Rajan                            Crassidis                   Mollendorf                      Nouh

FACULTY AWARDS
              Biomedical Engineering: Albert Titus was                       Clarivate Analytics; Michel Bruneau received            Ergonomics Society; Sabrina Casucci was
                named a Fellow of the National Academy of                    a Special Achievement award from the                    named a 2020 Open SUNY Online Teaching
                Inventors; Leslie Ying was named a Fellow                    American Institute of Steel Construction;               Ambassador; Lora Cavuoto received the
                of the American Institute for Medical and                    Negar Elhami Khorasani received an Early                President Emeritus and Mrs. Meyerson
                Biological Engineering.                                      Career Faculty award from the American                  Award for Distinguished Undergraduate
              Chemical and Biological Engineering: Paschalis                 Institute of Steel Construction.                        Teaching and Mentoring from UB; Jun
                Alexandridis was named a Fellow of the                  Computer Science and Engineering: Wenyao                     Zhuang received the Excellence in Graduate
                Royal Society of Chemistry; Amit Goyal was                   Xu received the President Emeritus and                  Student Mentoring Award from UB and was
                named a SUNY Distinguished Professor and                     Mrs. Meyerson Award for Distinguished                   included in Buffalo Business First’s list of 40
                a Fellow of the Institute of Electrical and                  Undergraduate Teaching and Mentoring                    Under 40 honorees.
                Electronics Engineers; Johannes Hachmann                     award from UB; Junsong Yuan was named              Materials Design and Innovation: Krishna
                received a SUNY Chancellor’s Award for                       a Fellow of the Institute of Electrical and             Rajan was named SUNY Distinguished
                Excellence in Teaching; Haiqing Lin received                 Electronics Engineers.                                  Professor.
                an Innovation Award from the Separations                Electrical Engineering: Vladimir Mitin was              Mechanical and Aerospace Engineering: John
                Division of the American Institute of                        named a Fellow of the Optical Society                   Crassidis was named SUNY Distinguished
                Chemical Engineers; Sriram Neelamegham                       of America; Kwang Oh received a SUNY                    Professor and a Fellow of the American
                was named a Fellow of the Biomedical                         Chancellor’s Award for Excellence in                    Society of Mechanical Engineers; Joseph
                Engineering Society; Thomas Thundat was                      Teaching award.                                         Mollendorf was inducted into the Niagara
                named a Fellow of the Institute of Electrical           Industrial and Systems Engineering: Rajan                    Frontier Aviation and Space Hall of Fame;
                and Electronics Engineers.                                   Batta received a Military Operations                    Mostafa Nouh received the Gary Anderson
              Civil, Structural and Environmental                            Research journal award for best paper; Ann              Early Achievement award from the
                Engineering: Panos Anastasopoulos was                        Bisantz received the Woman Mentor of the                Aerospace Division of the American Society
                named a Highly Cited Researcher by                           Year award from the Human Factors and                   of Mechanical Engineers.

10        |   BUFFALO ENGINEER 2021
SEAS PROFESSIONAL
                               DEVELOPMENT PROGRAMS EARN
                               IELTS USA BEST
                               PRACTICES AWARD                                                                                                                         Eli Ruckenstein

                                   Ensuring that all graduate students, both domestic and international, are ready
                               to contribute to the job market is one of the core values of the School of Engineering     T R I B U T E S TO O U R
                               and Applied Sciences.                                                                      E M E R I T U S FA C U LT Y
                                   The International English Language Testing System (IELTS) USA along with the
                               recommendations of the Higher Education Advisory Council, recently recognized              The SEAS Community will fondly remember
                               the school’s efforts in this area with its Best Practices in International Enrollment      these outstanding faculty members and their
                               Management Award.                                                                          valued contributions to our school.
                                   The award cites the SEAS 360° Professional Development Program,
                               a collaboration between the School of Engineering and Applied Sciences,                    Eli Ruckenstein, a UB faculty member for nearly 50 years
                               International Student Services, Alumni Relations, Blackstone Launchpad and                 who was awarded the U.S. National Medal of Science
                               Career Services, as being critical to the successful recruitment and retention of its      for his groundbreaking research in chemical engineering
                               international students.                                                                    and other fields, passed away Sept. 30 at the age of
                                   According to IELTS, “The University at Buffalo, SEAS 360°, and its collaborators       95. Lauded for his prolific and imaginative research,
                               are an example of an outstanding international enrollment management model that            Ruckenstein, SUNY Distinguished Professor Emeritus, was
                               sets institutional goals for recruitment, retention, and graduation of international       one of the most influential chemical engineers of his era,
                               students. The variety of internal and external stakeholders demonstrates the               as well as one of UB’s most renowned faculty members.
                               importance of working in unison to foster an environment where international               Read the obituary here: https://bit.ly/3rhnm5z
                               students have equal and equitable opportunities to take full advantage of their
                                                                                                                          William J. Rae, SUNY Distinguished Teaching Professor
                               education.”
                                                                                                                          Emeritus in the Department of Mechanical and
                                   IELTS USA provides English language assessment literacy to support strategic
                                                                                                                          Aerospace Engineering, died on July 15 at home at the
                               international enrollment management initiatives that link admissions and
                                                                                                                          age of 90. An expert in the fields of aerospace, flight
                               recruitment practices to institutional support programs at their network of more
                                                                                                                          dynamics and fluid mechanics, Rae joined UB in 1985,
                               than 3,400 higher education institutions and organizations.
                                                                                                                          and worked for over 30 years as a research scientist
                                                                                                                          and engineer at the Cornell Aeronautical Laboratory
                               Members of the SEAS 360° program team outside Davis Hall. From left are: Jude
                               Butch, Ed Brodka, Holly Justice, Katie Lengel, Lauren Rothschild, Lindsay DiAngelo,        (which later became Calspan). He was instrumental in
                               Jennifer Gammell, Kate Tudini and Christopher Connor. Not pictured are Hadar               the creation of CUBRC. Read the obituary here:
                               Borden, Todd Brooks, Betty Johnson, Bethany Mazur and Jim Wehrfritz.                       https://bit.ly/3uRJSEq

                                                                                                                          John Medige, Emeritus Professor in the Department
                                                                                                                          of Mechanical and Aerospace Engineering, passed
                                                                                                                          away peacefully at home in Buffalo on January 21,
                                                                                                                          2021, at the age of 90. He founded the biomechanics
                                                                                                                          lab in conjunction with UB’s Department of Orthopedics,
                                                                                                                          the first such collaboration between the engineering
                                                                                                                          and medical schools. Read the obituary here:
                                                                                                                          https://legcy.co/2Prrceo

                                                                                                                          Alan Selman, long-time faculty member and former
                                                                                                                          chair of the Department of Computer Science and
                                                                                                                          Engineering, passed away on January 22, 2021. He was
                                                                                                                          79. Selman was an expert on complexity theory, and
                                                                                                                          many colleagues will fondly recall “P NE NP.”
Photo: Maximilian Kapitonoff

                                                                                                                          Read the obituary here: https://bit.ly/3sOqOoB

                                                                                                                        UB School of Engineering and Applied Sciences               |   11
SCHOOL NEWS

10   QUESTIONS
WITH DEAN KEMPER LEWIS

Kemper E. Lewis, PhD, MBA, was named dean of the School of Engineering and Applied Sciences                     What can alumni do to help you and
on May 1, 2020, following a national search. A global leader in engineering design, system
                                                                                                                the school reach its goals?
                                                                                                                Do their jobs really well as that will make their
optimization and advanced manufacturing, Lewis joined UB in 1996. He is also the Moog Professor
                                                                                                                companies aspire to hire more students from UB.
of Innovation in the Department of Mechanical and Aerospace Engineering, where he served as                     Also, we want to expand our mentoring networks
department chair prior to being named dean, and the director of UB’s Community of Excellence                    and programs. The best mentors are those who
                                                                                                                are a season ahead and our alumni can play a
in Sustainable Manufacturing and Advanced Robotic Technologies (SMART). He succeeds Rajan
                                                                                                                significant role by being mentors for our students.
Batta, a SUNY Distinguished Professor in industrial and systems engineering, and the SEAS
Associate Dean for Faculty Affairs and Diversity, We talked with Lewis about his thoughts on                    What has been most rewarding
                                                                                                                about serving as the SEAS dean?
leading the school, and his vision for the future.
                                                                                                                Being able to work with the outstanding
                                                                                                                leadership teams we have in SEAS and at the
You enjoyed success in your academic                       Obviously, the pandemic has had an                   university level to address difficult but critical
career as a teacher, researcher and                        enormous impact on universities across               issues. I have also greatly enjoyed hearing
administrator. What drove your decision                    the county. What do you see as its                   how our students have adapted and are
to become a dean?                                          greatest impact on SEAS?                             positioning themselves as emerging leaders
                                                                                                                across many fields.
What’s great about being a dean is that I still get        With every crisis comes opportunity. For instance,
to be a teacher, researcher and administrator,             we have had significant challenges onboarding
                                                                                                                Serving as dean is demanding —
but how those responsibilities get accomplished            our outstanding international students. At the
have changed. For example, I get to apply                  same time, this allowed us the opportunity to
                                                                                                                how do you unwind and relax?
design thinking and decision theory to the                 develop a robust and innovative set of online        My faith and family are of utmost importance to
development of broader research initiatives                programs and onboarding initiatives for our          me and where I find great solace, purpose and
that involve many of our terrific faculty and their        students. As another example, the pandemic           strength. I also enjoy exploring all the outdoor
collective expertise.                                      forced our research labs to pivot how they           experiences we have in Western New York,
                                                           operated. But this pivot allowed our faculty         including trail running, cycling and camping.
                                                           to develop new research plans and creative
                                                           partnerships that have created new momentum          What is your favorite place on campus?
                                                           with significant success.                            This is a great question. It’s hard to narrow down
                                                                                                                to one, but I enjoy Baird Point, Grace Plaza, the
                                                           Looking down the road, where do you see              Amherst biking path that winds through campus,
                                                           SEAS in the next 5-10 years?                         and Alumni Arena during a UB Bulls basketball
                                                           I see SEAS sustaining and accelerating our           game. Of course, anywhere in our SEAS footprint
                                                           excellence across research, education, outreach      is a great place to be since it’s where my friends,
                                                           and partnerships, establishing our position as       peers and colleagues are. And once we are able
                                                           one of the preeminent public research institutions   to build the new engineering building, that will
                                                           in the nation. At our core will persist our values   have some unique features that we will all get to
                                                           of achievement, diversity, integrity, tenacity,      enjoy as well.
                                                           collaboration and collegiality.
                                                                                                                Who makes the best wings in Buffalo?
                                                           What would alumni who graduated 20                   This is a trap question since I will offend readers
                                                           or more years ago be surprised to know               regardless of what I say. I’m actually not a big
                                                           about the school today?                              fan of wings, but Buffalo pizza...now we’re
                                                                                                                talking! I haven’t met a slice I have not liked.
                                                           That we don’t have the dreaded trailers any
                                                                                                                Picasso’s, Luigi’s, Lovejoy, Good Guys, Just Pizza,
                                                           longer :). Actually, what may be less known is
                                                                                                                Bocce, are all up there for me. You can’t go
                                                           that we have doubled in size, allowing us to
                                                                                                                wrong in Buffalo for pizza!
                                                           greatly expand learning experiences for our
                                                           students and research capabilities. We are now
                                                           the #1 ranked public engineering and computer        Cat or dog?
                                                           science school in New York.                          Nothing against cats, but it is dog for me.
                               Photo: Onion Studio, Inc.

                                                                                                                                               by Jane Stoyle Welch
12    |   BUFFALO ENGINEER 2021
2021 ENGINEERING                                                                DEAN’S ADVISORY
                                                                                COUNCIL
PARTNERS                                                                        Michael J. Cadigan, Chair, Senior Vice President,
                                                                                   Worldwide Sales and Customer Engagement,
                                                                                   Globalfoundries
                                                                                Patrick Abrami, Partner and Consultant, Applied
                                                                                   Management Systems
GO L D PA RT NE RS                                                              Russell L. Agrusa, Founder, President and CEO,
                                                                                   ICONICS, Inc.
                                                                                Paul Ameis, General Manager, Lockport VanDeMark
                                                                                Ron Benczkowski, Vice President – Engineering,
                                                                                   Moog Inc., Space and Defense Group
                                                                                Nathan Bolt, Project Engineer, Turner Construction
                                                                                James Chou, Chief Technology Officer, Kabbage, Inc.
                                                                                Daniel D’Angelo, P.E., Principal Civil Engineer, Applied
                                                                                   Research Associates
                                                                                Dennis Elsenbeck, Head of Energy and
                                                                                   Sustainability, Energy Consulting Services,
                                                                                   Buffalo, Phillips Lytle LLP
                                                                                Judy Feldman, Executive Vice President, Chief
                                                                                    Information Officer, ValueCentric
                                                                                Robert Girardi, Retired, former President and CEO of
                                                                                   SofTrek
                                                                                Karianne Gomez, Vice President of Strategic Value at
                                                                                   the Network of Executive Women
                                                                                Robert G. Harrison, P.E., Vice President of Engineering
                                                                                   and Construction, Transmission Developers, Inc.
                                                                                Cynthia Hoover, Executive Director, Linde
                                                                                Rob Jacoby, Consultant to the Energy Industry
                                                                                Joe Kessler, Chief Operating Officer, New York Power
                                                                                    Authority
                                                                                Anil Kshirsagar, Executive Chair, CAPIOT Software, Inc
                                                                                Gina Lee-Glauser, Vice President for Research and
                                                                                   Scholarship; Provost Office at Clarkson University
                                                                                Jeff Markin, Chief Operating Officer, eHealth
                                                                                     Technologies
                                                                                Susan R. Nowicki, Director of Engineering, Northrop
                                                                                   Grumman Amherst Systems
                                                                                Mark Santoro, Principal Engineering Fellow for
SI LV E R PA RT NERS                                                               Space and Airborne Systems, Hardware
                                                                                   Engineering Center, Raytheon
                                                                                Ashish Shah, Vice President of Research and
                                                                                   Development, Viant, Inc.
                                                                                Alice Smith, Joe W. Forehand/Accenture Distinguished
                                                                                    Professor of the Industrial and Systems Engineering
                                                                                    Department, Auburn University
                                                                                Stephen E. Still, Retired, Former co-founder and
                                                                                   consultant, Seabury Airline Planning Group LLC
                                                                                Subbarao Vanka, President, NW Engineering
                                                                                   Consultants, Inc.
                                                                                Jonathan Watts, Vice President at Watts
                                                                                    Architecture & Engineering DPC
                                                                                Candace Yano, Gary & Sherron Kalbach Chair
                                                                                   in Business Administration and Professor
                                                                                   of Operations and Information Technology
                                                                                   Management, University of California, Berkeley

To become an engineering partner, contact Nick Lane at nmlane2@buffalo.edu
or Christine Human at chuman@buffalo.edu.

                                                                             UB School of Engineering and Applied Sciences           |   13
DISCOVERING

AT THE
                                                                                                           TREATMENTS
                                                                                                           FOR COVID-19
                                                                                                           Sriram Neelamegham, a professor in the

FOREFRONT
                                                                                                           Department of Chemical and Biological
                                                                                                           Engineering, and colleagues are developing
                                                                                                           molecular strategies to inhibit SARS-CoV-2, the

OF THE
                                                                                                           virus that causes COVID-19. The spike protein
                                                                                                           of this virus has several carbohydrates, known
                                                                                                           as glycans, attached to it. The overarching
                                                                                                           goal of the research is to identify weaknesses in

PANDEMIC
                                                                                                           viral binding, entry and replication that can be
                                                                                                           exploited for therapeutic benefit. Their studies
                                                                                                           have revealed that glycan epitopes expressed on
                                                                                                           the virus may serve as novel druggable targets.
                                                                                                           They observed that modifying carbohydrate
                                                                                                           epitopes using both genetic approaches and
 From vaccine development to mental                                                                        small molecules may enable fine-tuning of viral
 health apps, our researchers have                                                                         entry into host cells. The small molecule inhibitors
                                                                                                           they are evaluating represent potential drugs that
 stepped up to help.                                                                                       could be used to ameliorate COVID-19 as well as
 by Jane Stoyle Welch                                                                                      other viral infections.

                                                                                                           The paper, “Inhibition of SARS-CoV-2 viral entry
 Faculty, students and staff in the School of Engineering                                                  upon blocking N- and O-glycan elaboration,”

 and Applied Sciences are collaborating with colleagues                                                    was published by eLife.

 across the University, the region and the world, sharing
 their expertise to address critical issues related to the
 pandemic. Here we present some of our ongoing research
 initiatives and results, as well as a few examples of other
 ways that the engineering and applied sciences community
 has stepped up to help.

                                                                                                           A molecular model of SARS-CoV-2 Spike protein
                                                                                                           binding to human ACE2.

 MORE EFFECTIVE VACCINES
 Biomedical engineer Jonathan Lovell is the lead investigator of a research team that has discovered a technique
 to increase the effectiveness of vaccines against the novel coronavirus. Lovell’s team had previously developed a
 technology to convert small, purified proteins into particles through the use of liposomes, or small nanoparticles
 formed from naturally-occurring fatty components. In the new study, the researchers included a special lipid within
 the liposomes called cobalt-porphyrin-phospholipid, or CoPoP, which enables the receptor-binding domain (RBD)
 protein to rapidly bind to the liposomes, forming more nanoparticles that generate an immune response. When
 laboratory mice and rabbits were immunized with the RBD particles, high antibody levels were induced. Compared
 to other materials that are combined with the RBD to enhance the immune response, only the approach with
 particles containing CoPoP gave strong responses. Other vaccine adjuvant technology does not have the capacity
 to convert the RBD into particle-form. The vaccine is now entering clinical trials in South Korea in partnership with
 Eubiologics, a South Korean vaccine maker.

 The paper, “SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination,” was
 published in Advanced Materials. The study was supported by the National Institutes of Health, and the Facility
 for Electron Microscopy Research at McGill University.

14   |   BUFFALO ENGINEER 2021
WASTEWATER SURVEILLANCE
                                                     FOR COVID-19
                                                     Ian Bradley, an assistant professor in the Department of Civil, Structural and
                                                     Environmental Engineering and the RENEW Institute, is leading a pilot program with
                                                     environmental engineering colleagues Yinyin Ye, assistant professor, and Ning Dai,
                                                     associate professor, to monitor wastewater from all of the treatment plants located
                                                     in Erie County, which includes the city of Buffalo. The researchers are working on an
                                                     analysis of all the data that has been collected since September with the aim to create
                                                     a public dashboard in collaboration with the Erie County Department of Health and
                                                     Sewer Authority.

                                                     Bradley is also piloting an innovative wastewater surveillance approach to monitor a
                                                     wide range of viral infections on campus, extending the capacity of current wastewater
                                                     surveillance techniques that are based on genome detection. The project involves
                                                     interdisciplinary collaborations between environmental engineers and analytical
MAKING SAFER,                                        chemistry faculty and students to develop methods for detection of viral proteins and

REUSABLE MASKS                                       levels of antiviral drugs and other pharmaceuticals, such as anti-inflammatory drugs
                                                     that are used in managing complications of viral infections in wastewater. Yinyin Ye is a
Mark Swihart, professor and chair of the             co-investigator on the project.
Department of Chemical and Biological
Engineering, and his team, in collaboration with
faculty from UB’s Jacobs School of Medicine
and Biomedical Sciences and the School of
Dental Medicine, have developed materials for
antimicrobial masks with possible COVID-19
implications. While face masks are effective in
limiting transmission, most medical-grade face
masks are not self-sterilized or reusable. Their
widespread use consumes tremendous resources
and generates a corresponding amount of waste.

Swihart’s team developed a novel material
for treating the filtration media used in
medical-grade masks to inhibit the growth of
microbes. They have produced thin copper@
ZIF-8 core-shell nanowires, where ZIF-8 is a
zinc-based metal organic framework. When a           REDUCING WORRY AND STRESS IN
virus- or bacteria-laden droplet contacts these
nanostructures, they slowly release copper and
                                                     LOW INCOME NEIGHBORHOODS
zinc ions, which can kill bacteria and deactivate    Wenyao Xu is part of a team of UB researchers who are helping adults living in low-
viruses. These were applied to filtration media      income, racial- and ethnic-minority neighborhoods reduce stress due to the COVID-19
by simple dip-coating to uniformly cover the         pandemic. The $2.5 million award comes from the independent and non-profit
filter fibers. This ensures any deposited droplets   Patient-Centered Outcomes Research Institute. The research team will compare a
will contact the nanomaterial, while requiring       video conference mindfulness-based stress reduction (MBSR) group intervention to a
miniscule amounts of the material. The filtration    MBSR mobile app. Both approaches seek to reduce worry among adults living in these
performance of the media was maintained or           areas who have limited or reduced access to mental health care, particularly due to
improved. The proposed low-cost and scalable         the pandemic. Xu, an associate professor in
synthesis of Cu@ZIF-8 NWs and straightforward        the Department of Computer Science and
deposition onto filter media has great potential     Engineering, is leading the technical team
for creating reusable face masks and other           in the development of the app. The app will
medical textiles to reduce disease transmission,     provide an innovative alternative to current
resource consumption and environmental impact        mental health care. It is more accessible,
of waste.                                            portable and cost-effective, and lowers the
                                                     barriers to treatment. The project is led by
The paper, “Copper@ZIF-8 Core-Shell Nanowires
                                                     the UB School of Nursing, and the contract
for Reusable Antimicrobial Face Masks,” was
                                                     is one of seven awarded by the Institute
published in Advanced Functional Materials.
                                                     nationwide through a special COVID-19-
                                                     targeted funding announcement.

                                                                                    UB School of Engineering and Applied Sciences            |   15
BETTER MATERIALS                                                    DEVELOPING LOW-COST VENTILATORS
FOR MASKS                                                           Early in the pandemic, there was a severe shortage of ventilators needed by critically
                                                                    ill COVID-19 patients. In response to this need, a team of engineers and doctors joined
Prathima Nalam, assistant professor in the
                                                                    forces on a fast prototyping project based on additive manufacturing technology
Department of Materials Design and Innovation,
                                                                    and resources from the open source motion control community. The system is based
and Anirban Dutta, assistant professor in the
                                                                    on a mechanical actuating device that is coupled to a manual Ambu bag. Additive
Department of Biomedical Engineering, shared
                                                                    manufacturing technology was used to construct the mechanical ventilator and a
their expertise on mask materials with the
                                                                    mechatronic system was developed to achieve reliability and motion control accuracy.
community group MadeToAid. They suggested
                                                                    Early tests showed that the system could achieve a respiration rate up to 30 cycles per
some techniques for using
                                                                    minute and a maximum pressure of more than 60 cmH2O. Under atmospheric pressure,
common fabrics and other
                                                                    the delivery volume of each respiration achieved 750 ml, which meets the basic clinical
readily available products to
                                                                    requirement. The team’s first basic functional version was delivered for testing within 72
improve filtration effectiveness
                                                                    hours.
and reduce viral transmission.
                                                                    As a case study for implementation of fast prototyping technologies with limited
MadeToAid’s fabrication and
                                                                    resources, the project has great potential to assist the health care community under
distribution effort is helping
                                                                    crisis conditions like the COVID-19 pandemic. The
to close the PPE need gap,
                                                                    project team includes Chi Zhou, associate
as well as the product quality
                                                                    professor, and Tianjiao Wang, PhD
gap, by bringing together area
                                                                    student, Department of Industrial
designers, manufacturers, the
                                                                    and Systems Engineering; and
DIY community and UB faculty from across the
                                                                    colleagues from UB’s Jacobs
university, including the School of Architecture
                                                                    School of Medicine and
and Planning, College of Arts and Sciences, and
                                                                    Biomedical Sciences. It
the Community for Global Health Equity.
                                                                    was partially funded by the
                                                                    National Science Foundation.

                                                                                               IMPACT OF COVID-19 ON AIR
                                                                                               POLLUTION IN URBAN AREAS
                                                                                               To learn how air pollution has changed in populated areas of
                                                                                               the world, and how these changes might impact the chemistry
                                                                                               of the atmosphere in the future, Kang Sun is studying three
                                                                                               polluted regions: Southern California, the Jianghan Plain

HELPING THE HOMELESS
                                                                                               (which includes Wuhan) in China and the Po Valley in Italy,
                                                                                               where once-congested streets were made easily navigable by
Albert Titus, professor and chair of the Department of Biomedical                              travel restrictions associated with the novel coronavirus. Sun,
Engineering, was part of a group from UB that donated more than 200                            an assistant professor in the Department of Civil, Structural
reusable 3D-printed face masks and 100 face shields to the Buffalo City                        and Environmental Engineering and the RENEW Institute, is
Mission. The masks and face shields were created by UB’s 3D printing                           developing a new data-driven framework that combines
group, which formed at the start of the pandemic as a partnership among                        satellite and meteorological data, that will take NASA satellite
faculty, staff and students in the School of Dental Medicine, School of                        assets one step further to quantify the reduction in emissions
Engineering and Applied Sciences and the Jacobs School of Medicine                             and their impact on atmospheric chemistry. The resulting
and Biomedical Sciences.                                                                       framework can eventually be quickly applied to other regions.
                                                                                               The project is funded by a grant from NASA’s Earth Science
Early in the pandemic, the UB group teamed up with the Buffalo chapter
                                                                                               Division, through its Rapid Response and Novel Research in
of e-NABLE, the international, open-source 3D printing movement that has
                                                                                               Earth Science initiative.
stepped up during the pandemic to produce personal protective equipment
for communities all over the world. Together, they developed designs and
physical prototypes, and published the designs so that anyone could produce
the face shields and masks.

16    |   BUFFALO ENGINEER 2021
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