International Catalogue 2020/2021 - Immunohistochemistry - Selected Reagents for Diagnostics and Research - Zytomed Systems

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International Catalogue 2020/2021 - Immunohistochemistry - Selected Reagents for Diagnostics and Research - Zytomed Systems
Immunohistology

                                                       Detection Systems

                                                       Ancillary Reagents

                                                       Control Material

International Catalogue 2020/2021
Immunohistochemistry – Selected Reagents for Diagnostics and Research
International Catalogue 2020/2021 - Immunohistochemistry - Selected Reagents for Diagnostics and Research - Zytomed Systems
Zytomed Systems GmbH

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    Phone +49 30 80 49 84 990 | Fax +49 30 80 49 84 999

international@zytomed-systems.de | www.zytomed-systems.com
International Catalogue 2020/2021 - Immunohistochemistry - Selected Reagents for Diagnostics and Research - Zytomed Systems
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International Catalogue 2020/2021 - Immunohistochemistry - Selected Reagents for Diagnostics and Research - Zytomed Systems
Content
    Antibodies
    Positive control list for primary antibodies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5

    Information about Zytomed Systems antibodies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10

    Selected primary antibodies. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10

    Max-Line antibodies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70

    Detection Systems
    ZytoChem Plus Polymer detection kits and reagents .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 73

    Double Stain Polymer detection kits . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74

    ZytoChem Plus Streptavidin Biotin detection kits and reagents .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74

    Ancillary Reagents
    Epitope retrieval .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 77

    Chromogenic substrates . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78

    Diluents, buffers and miscellaneous .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79

    Control Material
    Cell Control Blocks . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 81

    Cell Control Slides. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 82

    Information
    Master list for immunohistochemistry . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85

    Register . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 87

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              www.zytomed-systems.com
International Catalogue 2020/2021 - Immunohistochemistry - Selected Reagents for Diagnostics and Research - Zytomed Systems
Antibodies

             Antibodies

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International Catalogue 2020/2021 - Immunohistochemistry - Selected Reagents for Diagnostics and Research - Zytomed Systems
Compilation of positive controls for primary
   antibodies used in immunohistochemistry
                    Antigen/Antibody Positive control                                               Antigen/Antibody Positive control

                                                                                                                                                                   Antibodies
                          14-3-3 Beta Protein    Prostate carcinoma, liver tumour                             CA 125 Antigen     Ovary carcinoma,
                          14-3-3 Zeta Protein    Breast carcinoma                                                                colon carcinoma
                                         ACTH    Pituitary gland                                              Cadherin (Pan)     Tonsil
                               Actin (Muscle)    Skeletal muscle                                                 Cadherin 17     Colon carcinoma
                         Actin (Muscle, Pan)     Skeletal muscle                                                  E-Cadherin     Ductal breast carcinoma
                    Actin alpha (Sarcomeric)     Skeletal muscle                                                    Calbindin    Kidney
               Actin alpha (Skeletal Muscle)     Skeletal muscle                                                   Calcitonin    Thyroid gland
               Actin alpha (Smooth Muscle)       Leiomyosarcoma                                           Caldesmon (HMW)        Skeletal muscle
                                Actinin alpha    Skeletal muscle
                                                                                 Calmodulin-dependend Protein Kinase IV          Brain
                                  Adenovirus     Adenovirus-infected tissue
                                                                                                                      Calpain    Breast carcinoma
ADH-5 (Breast Marker Double Stain Cocktail)      Breast carcinoma
                                                                                                                  Calpastatin    Breast carcinoma
                    AFP (Alpha Fetoprotein)      Fetal liver
                                                                                                                     Calponin    Breast carcinoma
                                          Akt1   Breast carcinoma
                                                                                                                    Calretinin   Mesothelioma
                                       Akt1/2    Breast carcinoma
                              Albumin (HSA)      Liver
                                                                                               Carbonic Anhydrase IX (CA IX)     Placenta
       Aldh 1a1 (Alkohol Dehydrogenase 1)        Colon carcinoma, breast carcinoma                                 Caspase 1     Clear cell RCC
   ALK /p80 (Anaplastic Lymphoma Kinase)         ALK-positive lymphoma                                     Caspase  3 (CPP32)    Tonsil
                  Alpha-1-Antichymotrypsin       Tonsil                                           Caspase 3, cleaved (CPP32)     Tonsil, colon carcinoma, apoptotic cells
                   Alpha-1-Antitrypsin (AAT)     Tonsil                                                    Caspase 6 (MCH2)      Tonsil
                      Alpha-2-Macroglobulin      Tonsil                                                     Caspase 8 (FLICE)    Stomach
                            Amylin (Peptide)     Pancreas                                                 Caspase  9 (Apaf-3)    Stomach, tonsil
                      Amyloid A Component        Kidney                                                  Caspase 10 (FLICE2)     Liver carcinoma
                          Amyloid Beta (A4)      Alzheimer brain                                              Catenin (alpha)    Breast carcinoma
                       Amyloid Beta-Protein      Alzheimer brain                                               Catenin (beta)    Breast carcinoma
           Amyloid Precursor Protein (APP)       Brain                                                  Catenin (delta), p120    Breast carcinoma
                         Androgen Receptor       Prostate carcinoma                          Catenin (gamma) (Plakoglobin)       Breast carcinoma
                                  Annexin A1     Hairy cell leukaemia                                            Cathepsin D     Breast carcinoma
                                  Annexin IV     Liver                                                   Cat Scratch Disease     Bartonella henselae-infected tissue
         APC (Adenomatous Polyposis Coli)        Colon carcinoma                                                   Caveolin-1    Lung carcinoma
       ATM (Ataxia Telangiectasia Mutated)       Breast carcinoma                                                        CCR7    Small intestine
                         BAG-1/RAP46/HAP1        Breast carcinoma                                                        CD1a    Histiozytosis X, tonsil
                                          Bak    Tonsil
                                                                                                                          CD2    Tonsil
                                          Bax    Hodgkin’s Lymphoma
                                                                                                                          CD3    Tonsil
                            BCA-225 (BRST-1)     Breast carcinoma
                                                                                                                     CD3 zeta    Jurkat cells, tonsil
                                         BCL2    Tonsil
                                                                                                                          CD4    Tonsil
                                         BCL6    Tonsil
                                                                                                                          CD5    Tonsil, mantle cell lymphoma
                                        BCL10    Tonsil
                                        BCL-X    Hodgkin’s lymphoma
                                                                                                                          CD7    Tonsil
                                       BCL-XL    Hodgkin’s lymphoma                                                       CD8    Tonsil
                                        BCRP     Drug-sensitive cell line (MCF-7), fetal intestine                        CD9    Tonsil
                                    beta-HCG     Placenta                                                       CD10  (CALLA)    Small intestine, tonsil
      BG-1 Precursor (Blood Group Antigen)       Kidney, ureter                                                         CD11c    Hairy cell leukaemia
              BG-2 A (Blood Group Antigen)       Kidney, ureter                                                          CD14    Tonsil, diffuse large-cell
              BG-3 B (Blood Group Antigen)       Kidney                                                                          B-cell lymphoma
              BG-4 0 (Blood Group Antigen)       Colon, colon carcinoma                                                  CD15    Reed-Sternberg cells, tonsil
        BG-5 Lewis a (Blood Group Antigen)       Colon, colon carcinoma                                                  CD19    Tonsil
       BG-6 Lewis b (Blood Group Antigen)        Colon carcinoma                                                         CD20    Tonsil
        BG-7 Lewis x (Blood Group Antigen)       Kidney                                                                  CD21    Tonsil
        BG-8 Lewis y (Blood Group Antigen)       Colon carcinoma                                                         CD23    Tonsil
                                    BOB.1        Tonsil, lymph node                                                  CD25        Tonsil
                                   BRCA1         Ovary carcinoma                                   CD29 (Integrin-beta1)         Cerebellum
                                      C3d        Graft rejection after kidney transplantation                  CD30 (Ki-1)       Small intestine, tonsil
                                     C4d         Graft rejection after kidney transplantation           CD31 (PECAM-1)           Placenta, tonsil
                          CA 19-9 (Colon)        Colon carcinoma                                 CD34 (Endothelial cells)        Tonsil
          CA 72.4 Antigen/TAG-72 (BRST-3)        Breast carcinoma                        CD35 (CR1) (Dentritic Reticulum)        Tonsil

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International Catalogue 2020/2021 - Immunohistochemistry - Selected Reagents for Diagnostics and Research - Zytomed Systems
Antigen/Antibody Positive control                                                 Antigen/Antibody Positive control

                                   CD40    Tonsil                                                                 Cyclin B1    Breast carcinoma, tonsil
       CD43 (Leukosialin, Sialophorin)     Lymph node, tonsil                                             Cyclin D1 (BCL-1)    Breast carcinoma, mantle
                         CD44 (H-CAM)      Tonsil                                                                              cell lymphoma, tonsil
                            CD45 (LCA)     Tonsil                                                                 Cyclin D3    Breast carcinoma, tonsil
                                CD45RA     Tonsil                                                                   Cyclin E   Breast carcinoma, placenta
Antibodies

                                CD45RB     Tonsil                                                                     Cyr61    Placenta
                                CD45RO     Lymph node, tonsil                                                    Cystatin A    Brain
            CD56 (N-CAM, NKH1, SCLC)       Small-cell lung carcinoma, neuroblastoma                    Cytokeratin (Acidic)    Skin
                        CD57 (NK cells)    Lymph node, tonsil                                           Cytokeratin (Basic)    Skin
                 CD61 (Integrin beta 3)    Tonsil                                                      Cytokeratin (HMW)       Skin, prostate
                        CD63 (NK-I/C3)     Melanoma                                                   Cytokeratin (OSCAR)      Bladder, skin, liver, breast carcinoma
                    CD68 (Macrosialin,     Tonsil                                                         Cytokeratin (Pan)    Skin, tonsil
                 macrophage antigen)                                                                 Cytokeratin Pan Plus      Skin, adenocarcinoma
                                    CD74   Tonsil                                           Cytokeratin (Wide Spectrum)        Skin
                                 CD79a     Tonsil                                                             Cytokeratin 4    Skin
                     CD95 (Fas, Apo-1)     Small intestine                                                    Cytokeratin 5    Skin
             CD95L (FAS Ligand) CD178      Prostate                                                       Cytokeratin 5 & 6    Skin, prostate
         CD99/MIC2 (Ewing’s sarcoma)       Ewing sarcoma, pancreas                                        Cytokeratin 5 & 8    Skin, lung
CD105 (Endoglin, TGF beta 1/3 Receptor)    Tonsil                                                        Cytokeratin 5 & 14    Skin, prostate
                           CD117 (c-Kit)   Tonsil, stroma tumour (GIST)                                       Cytokeratin 6    Skin
                   CD138 (Syndecan-1)      Plasmocytoma, tonsil                                               Cytokeratin 7    Skin, breast carcinoma
                                  CD163    Lung                                                               Cytokeratin 8    Skin
                         CD274 (B7-H1)     Tonsil, lung, skeletal muscle                                Cytokeratin 8 & 18     Skin, breast carcinoma
                                CDC25A     Tonsil                                                            Cytokeratin 10    Skin
                                CDC25B     Tonsil                                                      Cytokeratin 10 & 13     Skin
                                CDC25C     Breast carcinoma                                                  Cytokeratin 13    Skin
                                  CDC37    Thymus                                                            Cytokeratin 14    Skin, squamous cell carcinoma
                                  CDC47    Breast carcinoma                                                  Cytokeratin 15    Skin
     Cdk2 (Cyclin dependent Kinase 2)      Tonsil                                                            Cytokeratin 16    Skin, squamous cell carcinoma
     Cdk4 (Cyclin dependent Kinase 4)      Liposarcoma                                                       Cytokeratin 17    Skin
     Cdk5 (Cyclin dependent Kinase 5)      Brain                                                             Cytokeratin 18    Skin, lung carcinoma, breast carcinoma
                        CDw75 (B-Cell)     Tonsil                                                            Cytokeratin 19    Skin, colon carcinoma
                                    CDX1   Small intestine                                                   Cytokeratin 20    Colon carcinoma
                                   CDX2    Colon carcinoma                                        Cytomegalovirus (CMV)        CMV-infected tissue
CEA (Carcinoembryonic Antigen, CD66e)      Colon carcinoma                                                         Desmin      Leiomyoma
                                   c-FOS   Skin                                                               Desmoglein 3     Breast carcinoma
                                    CFTR   Pancreas                                      DHFR (Dihydrofolate Reductase)        Squamous cell carcinoma of lung
               Cholecystokinin (26-33)     Small intestine                                              DNA Polymerase B       Testicles
                      Chromogranin A       Pancreas                                                                   DOG1     Gastrointestinal stroma tumour
            CITED-1 (CBP, CREB-binding     Papillary thyroid gland carcinoma                                      Dysferlin    Skeletal muscle
                         protein, p300)                                                                         Dystrophin     Skeletal muscle
                              Claudin 1    Skin, breast carcinoma                               E2F-1 Transcription Factor     Breast carcinoma, tonsil
                              Claudin 2    Colon carcinoma, ovary carcinoma, tonsil             E2F-4 Transcription Factor     Breast carcinoma, tonsil
                              Claudin 3    Small intestine                                                      E-Cadherin     Ductal breast carcinoma
                              Claudin 4    Ovary carcinoma, tonsil             EGFr (Epidermal Growth Factor Receptor)         Placenta, squamous cell carcinoma
                              Claudin 5    Colon carcinoma, lung                                                     Elastin   Heart
                              Claudin 7    Colon carcinoma                           EMA (Epithelial Membrane Antigen)         Colon carcinoma, breast carcinoma
                             Claudin 10    Brain, skeletal muscle                       eNOS (endothelial NO-Synthase)         Vascular endothelia
           c- Met (Hepatocyte Growth       Breast carcinoma                    Epithelial Specific Antigen (ESA, Ep-CAM)       Breast carcinoma
                      Factor Receptor)                                          Epstein Barr Virus (EBV)(Cocktail)(LMP-1)      EBV-infected tissue
                                  c-Myc    Breast carcinoma                                                            ERAB    Alzheimer brain
                            Collagen IV    Skin                                                                       ERCC1    Tonsil, lung carcinoma
                           Connexin 43     Heart                                                                        ERG    Prostate carcinoma
             COX-1 (Cyclooxygenase 1)      Skin                                     ERK1 (Extracellular Regulated Kinase)      Breast carcinoma
             COX-2 (Cyclooxygenase 2)      Colon carcinoma, breast carcinoma ERK2 (Extracellular Regulated Kinase)             Breast carcinoma
                                   c-TEN   Liver carcinoma                                               Estrogen Receptor     Breast carcinoma
                                   CUL-1   Tonsil                                                 Estrogen Receptor beta       Breast carcinoma, ovary, endometrium
                                   CUL-2   Tonsil                                                    Ezrin (p81, Cytovillin)   Lung
                                   CUL-3   Tonsil                                                                     F4/80    Mouse lung
                                Cyclin A   Tonsil                      Factor VIII Related Antigen (v. Willebrand Factor)      Tonsil

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International Catalogue 2020/2021 - Immunohistochemistry - Selected Reagents for Diagnostics and Research - Zytomed Systems
Antigen/Antibody Positive control                                                   Antigen/Antibody Positive control

                     Factor XIIIa (Fibrinoligase,    Placenta                                  HSV I & II (Herpes Simplex Virus)         HSV I & II-infected tissue
                    Plasma Transglutaminase)                                                       HSV II (Herpes Simplex Virus)         HSV II-infected tissue
         Fas-Associated Phosphatase (FAP-1)          Placenta                           Huntingtin-Interacting Protein 1 (HIP-1)         Colon carcinoma
       FBXW7 Endometrial adenocarcinoma              Lung squamous cell carcinoma                                                 IgA    Tonsil
   FGFr1 (Fibroplast Growth Factor Receptor)         Breast carcinoma                                                             IgD    Tonsil

                                                                                                                                                                           Antibodies
  FGFr2 (Fibroplast Growth Factor Receptor)          Liver cell carcinoma                                                          IgE   Tonsil
  FGFr3 (Fibroplast Growth Factor Receptor)          Breast carcinoma                                                             IgG    Tonsil
                                      Fibronectin    Kidney                                                                     IgG4     Tonsil
                                             Fli-1   Angiosarcoma                                                                IgM     Tonsil
                   FLIP (Flice Inhibitor Protein)    Colon carcinoma, placenta                                              IKAROS       Tonsil
                Follicular Dendritic Cells (FDC)     Lymph node, thyroid gland, tonsil                              Inhibin, alpha       Ovary, testicles
                                           FOXA1     Breast carcinoma                                                           INI-1    Brain, astrocytome, endothelial cells
                                           FOXP3     Tonsil                                       iNOS (inducible NO-Synthase)           Lung
                     FOXP4 (Forkhead BOX P4)         Lung                                                                    Insulin     Pancreas
                  Fra2 (Fos Related Antigen 2)       Prostate carcinoma           Insulin-Like Growth Factor 1 Receptor (IGF1R)          Breast carcinoma, placenta
          FSH (Follicle Stimulating Hormone)         Pituitary gland                            Insulin Receptor Substrate (IRS)         Colon carcinoma
                                       Galectin-3    Thyroid gland                                         Integrin beta 3 (CD61)        Tonsil
  Gamma Glutamylcysteine Synthase (GCS)              Kidney, testicles                                             Integrin beta 5       Small intestine, bone marrow
                                          Gastrin    Stomach                                                            Involucrin       Skin
                                          GATA-3     Breast, urothelial carcinoma                  IPO-38 (Proliferation Marker)         Spleen, tonsil
                              GCDFP-15 (BRST-2)      Breast carcinoma, salivary gland                                           JAK3     Colon carcinoma, tonsil
          GFAP (Glial Fibrillary Acidic Protein)     Astrocytome, brain                                                     J-Chain      Tonsil
            Glial Derived Neurotrophic Factor        Brain tumour                                               Kappa Light Chain        Tonsil
                                        Glucagon     Pancreas                                                                  Ki-67     Breast carcinoma, tonsil
                GLUT1 (Glucose Transporter 1)        Breast carcinoma                                                  KOC/L523S         Prostate carcinoma, placenta
                GLUT3 (Glucose Transporter 3)        Placenta                                                                 K-RAS      Colon carcinoma
                   Glutamat Decarboxylase 65         Pancreas                                                        Ksp-Cadherin        Kidney
                                   Glycophorin A     Erythrocytes                                                         Ku (p70)       Tonsil
                       Glycophorin C (CD236R)        Tonsil                                                  Lactogen (Placental)        Placenta
                                       Glypican-3    Liver cell carcinoma                                     Lambda Light Chain         Tonsil
GNB2 (Guanine nucleotide binding protein 2)          Placenta                                                              Laminin       Skin
           Granulocyte (Myeloid Cell Marker)         Lymph node, tonsil                                                   Langerin       Langerhans cells
                                    Granzyme B       Hodgkin’s lymphoma, tonsil                                                 LK26     Ovary carcinoma
             Growth Hormone, human (hGH)             Pituitary gland                                                           LMO2      Tonsil
                            Hairy Cell Leukemia      Tonsil                         LPAP (Lymphocyte Phosphatase-Associated              Tonsil
      HCG (Human Chorionic Gonadotropin)             Placenta                                                    Phosphoprotein)
               HDAC1 (Histone Deacetylase 1)         Tonsil                                            Lung Related Protein, MV          Breast carcinoma, adrenal gland
              HDAC2 (Histone Deacetylase 2)          Tonsil                                                 (Major Vault Protein)
              Heat Shock Protein 60 (HSP60)          Breast carcinoma                                  Luteinizing Hormone (LH)          Pituitary gland
               Heat Shock Protein 70 (HSP70)         Breast carcinoma                            Lymphatic Endothelium Marker            Lymphatic endothelia (tonsil
                             Helicobacter pylori     H. pylori-infected tissue                                (D2-40, Podoplanin)        or appendix)
                                  Hemoglobin A       Bone marrow, spleen, placenta                    Lysozyme (Muraminidase)            Tonsil
            Hepatitis B Core Antigen (HBcAg)         HBV-infected liver                                                       LYVE-1     Lymphatic endothelia (tonsil
        Hepatitis B Surface Antigen (HBsAg)          HBV-infected liver                                                                  or appendix)
                        Hepatitis C Virus (HCV)      HCV-infected liver                                               Macrophage         Lymph node, tonsil
                         Hepatocyte (HepPar1)        Liver                                                                     MAdL      Adenocarcinoma of lung
             Hepatocyte Factor Homologue-4           Lung                                                                  MAGE-1        Melanoma, tonsil
        HER2 (c-erbB-2) Extracellulär domain         Breast carcinoma                                              Mammaglobin           Breast carcinoma
        HER2 (c-erbB-2) Intracellulär domain         Breast carcinoma                                            MART-1 (MelanA)         Melanoma
                                 HER3 (c-erbB-3)     Breast carcinoma, skeletal muscle                         Mast Cell Chymase         Tonsil
                                 HER4 (c-erbB-4)     Breast carcinoma                                           Mast Cell Tryptase       Tonsil
            Heregulin (NDF, GGF, Neuregulin)         Prostate carcinoma                           MCL-1 (Myeloid Cell Leukemia)          Tonsil
                                            HGAL     Tonsil, lymph node                                                       MCM2       Tonsil
                  HHV8 (Human Herpes Virus)          HHV8-infected tissue                                                     MCM5       Cervix carcinoma
              HIF-1 alpha ( Hypoxia Inducible        Breast carcinoma                          MDM2 (Murine Double Minute 2)             Breast carcinoma, liposarcoma
                                  Factor-1 alpha)                                                  MDR1 (Multi Drug Resistance           Colon, liver, kidney
                             HLA-DR, DP, DQ, DX      Lymph node, tonsil                                           Protein, pg170J)
                                          HMGA2      Breast carcinoma                  MDR1+3 (Multi Drug Resistance Protein)            Adrenal cortex
        HPV 16, L1 (Papilloma virus Type 16)         HPV 16-infected tissue                                                   MEF-2      Brain
                 HSV I (Herpes Simplex Virus)        HSV I-infected tissue

                                                                                                                                                                 7
Antigen/Antibody Positive control                                               Antigen/Antibody Positive control

                              Melanoma      Melanoma                                            Oct-2 (Octamer Binding      Tonsil
     (pan, MART-1+HMB45+Tyrosinase)                                                              Transcription Factor 2)
                    Melanoma (HMB45)        Melanoma                                    Oct-3/Oct-4 (Octamer Binding        Seminoma
        Melanoma Associated Antigen         Melanoma                                           Transcription Factor 3/4)
                             Mesothelin     Mesothelioma                                        Oct-4 (Octamer Binding      Seminoma
Antibodies

                          Mesothelioma      Mesothelioma                                         Transcription Factor 4)
                                   MGMT     Colon carcinoma, tonsil                                        Osteopontin      Stomach carcinoma, osteosarcoma
                         Microglia (Iba1)   Brain                                                                   Olig2   Astrocytoma
                             MIP-1alpha     Lung carcinoma                                                    p14 (ARF)     Breast carcinoma, cervix carcinoma
                  MiTF (Microphthalmia      Melanoma                                                p14 (ARF)/p16 beta      Cervix carcinoma, fibroadenoma of breast
                    Transcription Factor)                                                                    p15 (ink4b)    Colon carcinoma
                                   MLH1     Colon, melanoma, tonsil                                          p16 (ink4a)    Uterine cervical squamous cell carcinoma
   MMP-1 (Matrix Metalloproteinase 1)       Breast carcinoma, placenta                                      p19 (ink4d)     Colon carcinoma
   MMP-2 (Matrix Metalloproteinase 2)       Breast carcinoma, placenta                                  p21 (ros, WAF1)     Colon carcinoma, tonsil
   MMP-3 (Matrix Metalloproteinase 3)       Breast carcinoma, placenta                                        p27 (KIP1)    Colon carcinoma
   MMP-7 (Matrix Metalloproteinase 7)       Breast carcinoma, placenta                                       p34 (CDC2)     Breast carcinoma
   MMP-9 (Matrix Metalloproteinase 9)       Breast carcinoma, placenta                                               p40    Squamous cell carcinoma of lung
  MMP-10 (Matrix Metalloproteinase 10)      Breast carcinoma, placenta                                               p53    Colon carcinoma, breast carcinoma
  MMP-11 (Matrix Metalloproteinase 11)      Placenta                                                          p56 DOK2      Breast carcinoma
                       MMP-14/MT-MMP        Breast carcinoma, placenta                                        p57 (KIP2)    Colon carcinoma, placenta
          (Matrix Metalloproteinase 14)                                                                        p59 (Fyn)    Lymphoma
                      MMP-15/MT2-MMP        Placenta                                                          p62 DOK1      Breast carcinoma
          (Matrix Metalloproteinase 15)                                                                              p63    Skin, squamous cell carcinoma, prostate
  MMP-19 (Matrix Metalloproteinase 19)      Placenta                                               p120 (Catenin delta)     Breast carcinoma
  MMP-23 (Matrix Metalloproteinase 23)      Placenta                                                    P504S (AMACR)       Prostate carcinoma
            MSH2 (MutS homologue 2)         Colon carcinoma, tonsil                        P504S & p63 (PIN Cocktail)       Prostate carcinoma
            MSH3 (MutS homologue 3)         Colon carcinoma, tonsil                              Pan Basal-Cell Cocktail    Prostate, breast
            MSH6 (MutS homologue 6)         Colon carcinoma, tonsil                           (p63 & Cytokeratin 5/14)
                                   mTOR     Breast carcinoma                            Pan B Cocktail (CD20 & PAX-5)       Tonsil
                 MUC1 (Mucin 1, CD227)      Breast carcinoma                                    Pancreatic Polypeptide      Pancreas
                         MUC2 (Mucin 2)     Small intestine                      Par-4 (Prostate Apoptosis Response)        Alzheimer brain, myocardium
                  MUC 5AC (Mucin 5AC)       Stomach                                       Parathyroid Hormone (PTH)         Parathyroid gland
                         MUC18 (CD146)      Angiosarcoma                      Parathyroid Hormone Receptor 1 (PTHr)         Breast carcinoma
                          MUM1 Protein      Plasma cells, tonsil                                                   PAX-2    Kidney cell carcinoma
            Myelin Basic Protein (MBP)      Brain                                                                  PAX-5    Tonsil
                Myeloperoxidase (MPO)       Spleen, tonsil                                                         PAX-8    Kidney cell carcinoma
                                 Myo D1     Tonsil                                                               Paxillin   Colon carcinoma
                               Myogenin     Rhabdomyosarcoma                 PCNA (Proliferating Cell Nuclear Antigen)      Lymph node, tonsil
                              Myoglobin     Skeletal muscle                                                         PD-1    Tonsil, lymph node
                                  Myosin    Skeletal muscle                    PDGF (Platelet Derived Growth Factor)        Breast carcinoma
                                Napsin A    Adenocarcinoma of the lung                               PDGF (beta-chain)      Angiosarcoma
                                    NCK2    Breast carcinoma                         (Platelet Derived Growth Factor)
               N-Cadherin (Cadherin 2)      Pituitary gland                                       PDGFr-alpha (CD140a)      Ovary carcinoma
                                 Nephrin    Kidney                                                 PDGFr-beta (CD140b)      Ovary carcinoma
            Neurofilament H (200 kDa)       Brain                                                                  PD-L1    Tonsil, lung adenocarcinoma
     Neurofilament l & H (70/200 kDa)       Brain                                                               Perforin    Spleen
                       NF kappa B (p50)     Testicles                                      Phosphohistone H3 (pHH3)         Breast carcinoma, tonsil
               NF kappa B (p65) (rel A)     Placenta, prostate                                  Phospholipase C beta 1      Brain
                           NGF-Receptor     Neurofibroma                                   Phospholipase C gamma 2          Hodgkin’s lymphoma
                                  Nkx3.1    Prostate carcinoma                      Phosphoprotein (Pan) (PS/PT/PY)         Breast carcinoma
       eNOS (endothelial NO-Synthase)       Vascular endothelia                                        Phosphotyrosine      Breast carcinoma
         iNOS (inducible NO-Synthase)       Lung                                                               PI3K/p85     Placenta, Breast carcinoma
         uNOS (universal NO-Synthase)       Placenta                                                    PI3K/p110 beta      Placenta
                                 Notch-1    Colon carcinoma, breast carcinoma              PIN Cocktail (P504S & p63)       Prostate carcinoma
                            Nrf2 (TCF 11)   Placenta                           PLAP (Placental Alkaline Phosphatase)        Seminoma
         NSE (Neuron Specific Enolase)      Pancreas                                                        PML Protein     Lymphoma
      Nucleophosmin (NPM, Numatrin)         Tonsil                                 PMP22 (Peripheral Myelin Protein)        Nerve tissue
                                Occludin    Lung, A431 cells                                                       PMS2     Colorectal carcinoma
                 Oct-1 (Octamer Binding     Tonsil                                                 Pneumocystis carinii     Infected lung tissue
                  Transcription Factor 1)                                                                       Podocin     Kidney

             8                                                                                                                       www.zytomed-systems.com
Antigen/Antibody Positive control                                                     Antigen/Antibody Positive control

                                  Podoplanin     Lymphatic endothelia                                                              TFE3    Testis or renal cell carcinoma
                      Progesterone Receptor      Breast carcinoma                                                                          with Xp11.2 translocation
                                    Prohibitin   Heart                                  TGF alpha (Transforming Growth Factor)             Small intestine
       Prolactin (LTH, Luteotropic Hormone)      Pituitary gland                        TGF beta I (Transforming Growth Factor)            Placenta
  Protein Gene Product 9.5 (PGP9.5, UCH-L1)      Pancreatic carcinoma, tonsil                                   TGF beta I Receptor        Placenta

                                                                                                                                                                          Antibodies
             PSA (Prostate Specific Antigen)     Prostate                              TGF beta II (Transforming Growth Factor)            Small intestine
          PsAP (Prostatic Acid Phosphatase)      Prostate                             TGF beta III (Transforming Growth Factor)            Placenta
          PsCA (Prostate Stem Cell Antigen)      Prostate carcinoma                                           TGF beta III Receptor        Placenta
PSMA (Prostate Specific Membrane Antigen)        Prostate                                       Thioredoxin Reductase 2 (TrxR2)            Colorectal carcinoma
                          PTEN (MMAC1,TEP1)      Prostate, breast carcinoma                                              Thrombin R        Pancreas
                                          PU.1   Lymph node, tonsil                                        Thrombospondin (TSP)            Breast carcinoma
                                          Ran    Mamma, Hela- or A431 cells                            Thymidine Phosphorylase             Breast carcinoma
                                           Ras   Tonsil                                                     Thymidylate Synthase           Colon carcinoma
                                 RCAS (BAG9)     Breast carcinoma                                                     Thyroglobulin        Thyroid gland
            RCC1 (Regulator of Chromosome        Colon carcinoma                           Thyroid Hormone Receptor alpha 1/2              Colon carcinoma
                              Condensation1)                                                    Thyroid Hormone Receptor beta              Thyroid gland
          Renal Cell Carcinoma, gp200 (RCC)      Kidney, kidney cell carcinoma                          Thyroid Peroxidase (TPO)           Breast carcinoma, ovary carcinoma
                             Ret Oncoprotein     Small intestine, Colon carcinoma,                                               TIE-1     Tonsil
                        Retinoblastoma (Rb)      Breast carcinoma                                         TIMP-1 (Tissue Inhibitor         Colon carcinoma, pancreas
                                         R0C1    Tonsil                                                      of Metalloproteinase)         carcinoma
           RPA (p34) (Replication Protein A)     Tonsil                          TIMP-2 (Tissue Inhibitor of Metalloproteinase)            Breast carcinoma, Placenta
           RRM1 (Ribonucleotide Reductase        Placenta                        TIMP-3 (Tissue Inhibitor of Metalloproteinase)            Breast carcinoma, Placenta
                             M1 Polypeptide)                                                                             TNF (alpha)       Spleen
                                S6 Ribosomal     Breast carcinoma                                         TNFr-2 (Tumor Necrosis           Tonsil
                                         S100    Melanoma, nerve tissue                                           Factor Receptor 2)
                                      S100A4     Melanoma                                               Topoisomerase II (alpha)           Tonsil, mantle cell lymphoma
                                        S100P    Ductal adenocarcinoma of pancreas                       Topoisomerase II (beta)           Tonsil
                                        SALL4    Seminoma                                                        Toxoplasma gondii         Infected brain tissue
                                        SATB2    Colorectal adenocarcinoma                                                    TRADD        Liver carcinoma
                                Secretagogin     Pancreas, brain                                                          Transferrin      Liver
                                    Serotonin    Small intestine                                               Transglutaminase II         Breast carcinoma
                                       Smad3     Breast carcinoma                                             Treponema pallidum           Infected tissue
                               SMAD4 (DCP4)      Placenta                                                                     Trypsin      Pancreas
            Somatostatin Receptor 1 (SSTR1)      Prostate                                    TSH (Thyroid Stimulating Hormone)             Pituitary gland
         Somatostatin Receptor 2A (SSTR2A)       Pancreas including Langerhans cells        TTF-1 (Thyroid Transcription Factor 1)         Lung, thyroid gland
           Somatostatin Receptor 5 (SSTR5)       Pancreas including Langerhans cells                                  Tubulin, alpha       Skin, lung
                                         SOX2    Newborn brain                                                         Tubulin, beta       Skin, lung
                                         SOX4    Brain                                                                    Tyrosinase       Melanoma
                                         SOX9    Testicles                                                                  Ubiquitin      Alzheimer brain
                                        SOX10    Malignant melanoma, melanocytes                  uNOS (universal NO-Synthase)             Umbilical cord, placenta
                                        SOX11    Mantle cell lymphoma                    Upstream Transcription Factor 2 (USF2)            Breast carcinoma
                                        SOX14    Fetal tissue                                                               Urocortin      Pituitary gland
                                        STAT3    Tonsil                                                                  Uroplakin II      Urothelial tissue
                                       STAT5a    Tonsil                                                                 Uroplakin III      Urothelial tissue
                                        STAT6    Breast carcinoma                                                                          Urothelial carcinoma
                                    Stathmin     Tonsil, breast carcinoma, Jurkat-cells                            VEGF-A (Vascular        Astrocytome, haemangiosarcoma
                     Surfactant Apoprotein-A     Lung carcinoma                                       Endothelial Growth Factor)
                                     Survivin    Lymphoma                                                              VEGFr-1 (Flt-1)     Angiosarcoma
                               Synaptophysin     Pancreas                                                             VEGFr-2 (Flk-1)      Angiosarcoma
                          Syndecan-1 (CD138)     Tonsil                                                               VEGFr-3 (Flt-4)      Placenta, breast carcinoma
                                  Syntaxin 1A    Brain                                                                          VGSC       Brain
                            Synuclein (alpha)    Brain                                                                          Villin     Small intestine, kidney
 Synuclein (beta) (Phosphoneuroprotein 14)       Brain                                                                      Vimentin       Skin, melanoma, sarcoma
                              Synuclein (Pan)    Colon carcinoma, breast carcinoma                                           Vinculin      Skin
    TAG-72 (Tumor associated Glycoprotein)       Alzheimer brain                                                                WNT1       Breast carcinoma
                                          TAU    Thymus                                             WT1 (Wilm‘s Tumor Protein-1)           Wilm’s tumour
                                         T-bet   Tonsil, hairy cell leukaemia                                                  XRCC1       Testicles
             TdT (Terminal Deoxynucleotidyl      Squamous cell                                                                 XRCC2       Testicles
                                 Transferase)    carcinoma, tonsil                                                            ZAP-70       Tonsil
                                   Tenascin C    Tonsil, appendix                                                                ZO-3      Small intestine

                                                                                                                    This information is supplied without liability.
                                                                                                                                                                      9
Selected Primary Antibodies
                  for formalin-fixed paraffin-embedded tissue sections

                  Zytomed Systems offers a broad range of antibodies suitable for diagnostics. Usually, our antibodies are
Antibodies

                  available in concentrated and ready-to-use formats. All antibodies mentioned here are suitable for FFPE
                  tissue sections.

                  Ready-to-use antibodies: Designed for convenient handling, these antibodies require no dilution or
                  titration. Zytomed Systems offers 6 ml and 7 ml ready-to-use antibodies.

                  MAX-Line antibodies: These high-volume ready-to-use antibodies offer cost-effective solutions for
                  laboratories with manual as well as automated systems that have high throughput. They are available
                  in a 16 ml sizes.

                  Concentrated antibodies: To ensure highest flexibility in your immunohistochemistry protocol
                  Zytomed Systems offers 1 ml, 0.5 ml and 0.1 ml concentrated antibodies.

                  For a broad range of antibodies we offer protocol information for use on automated systems.
                  These protocols were provided by customers and have already been verified in the day-to-day routine
                  of an IHC laboratory. You can download a sheet with protocol recommendations from our homepage
                  or ask your local dealer for more information.

                  ACTH

                  Clone:        SPM501
                                                        Method     Format         Dilution        Amount           Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                       F, P    Concentrate       1:400             1 ml          501-16454
                  Pretreat.:    Citrate
                  Status:       RUO

                  Actin alpha (Skeletal Muscle)

                  Clone:        5C5.F8.C7
                                                        Method     Format         Dilution        Amount           Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                                                                  0.1 ml         501-16650
                                                          P      Concentrate        1:50
                  Pretreat.:    Citrate                                                              1 ml          501-16654
                  Status:       RUO

                  Actin alpha (Smooth Muscle)

                  Clone:        1A4
                                                        Method     Format         Dilution        Amount           Cat. No.
                  Host:         Mouse
                  Reactivity:   HU, MS, RT, CH                                                      6 ml           MSG030
                                                          P      Ready-to-use        -
                  Pretreat.:    -                                                                   16 ml           BMS001
                  Status:       CE/IVD
                                                                                                    0.5 ml        MSK030-05
                                                         P, IF   Concentrate       1:100
                                                                                                     1 ml           MSK030

                  ADH-5 Cocktail
                  Please refer to Cytokeratin 5 & 14.

             10                                                                                                                www.zytomed-systems.com
AFP (Alpha-Fetoprotein)

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                   F, P, WB             Concentrate                       1:200                         1 ml                     501-2954
Pretreat.:         -

                                                                                                                                                                                                                                                      Antibodies
Status:            RUO

AFP (Alpha-Fetoprotein)

Clone:             SP154
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU, BV, DG, PG                            P              Ready-to-use                           -                         7 ml                     501-4541
Pretreat.:         Citrate                                                                                                                  0.1 ml                    501-4540
Status:            RUO
                                                          P, WB              Concentrate                        1:100                      0.5 ml                     501-4542

                                                                                                                                             1 ml                     501-4544

Akt1, phosphorylated Ser473

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                       0.1 ml                   501-13450
                                                           F, P              Concentrate                         1:25
Pretreat.:         Citrate                                                                                                                   1 ml                     501-13454
Status:            RUO

ALK/p80 (Anaplastic Lymphoma Kinase)

Clone:             5A4
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU                                        P               Concentrate                  1:100 - 1:200                    0.5 ml                   MSK096-05
Pretreat.:         Citrate
Status:            CE/IVD

Alpha-1-Antichymotrypsin

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                   F, P, WB             Concentrate                        1:100                        1 ml                     501-3454
Pretreat.:         -
Status:            RUO

Alpha-Fetoprotein
Please refer to AFP.

AMACR
Please refer to P504S.

Reactivity: BV = Cow; CH = Chicken; DG = Dog; FE = Cat; FG = Frog, GT  = Goat; GP = Guinea pig; HM = Hamster; HS = Horse; HU = Human; MO = Monkey; MS = Mouse; PG = Pig; RB = Rabbit; RT = Rat; SH = Sheep; XE = Xenopus; ZF = Zebra fish a. o. = and others
Method: EL = ELISA; F = frozen sections IHC; FL = Flow Cytometry; IF = Immunofluorescense; IP = Immunoprecipitation; P = paraffin section IHC; WB = Western Blot
Status:     CE/IVD = for in vitro diagnostic use; RUO = Research use only                                                                                                                                                                      11
Amyloid Beta (A4)

                  Clone:        polyclonal
                                                    Method          Format      Dilution   Amount   Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                    F, P       Ready-to-use      -        7 ml    501-3531
                  Pretreat.:    -                                                          0.1 ml   501-3530
Antibodies

                  Status:       RUO
                                                  F, P, WB, IP   Concentrate     1:100     0,5 ml   501-3532

                                                                                            1 ml    501-3534

                  Amyloid Beta Precursor Protein (APP)

                  Clone:        polyclonal
                                                    Method          Format      Dilution   Amount   Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU, MS, RT          F, P, WB     Concentrate     1:100      1 ml    501-2654
                  Pretreat.:    Citrate
                  Status:       RUO

                  Anaplastic Lymphoma Kinase
                  Please refer to ALK.

                  Androgen Receptor

                  Clone:        SP107
                                                    Method          Format      Dilution   Amount   Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                     P         Ready-to-use      -        7 ml    501-4071
                  Pretreat.:    Citrate                                                    0.1 ml   501-4070
                  Status:       RUO
                                                     P, WB       Concentrate     1:400     0.5 ml   501-4072

                                                                                            1 ml    501-4074

                  Annexin I (ANXA1)

                  Clone:        polyclonal
                                                    Method          Format      Dilution   Amount   Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                                                         0.5 ml   501-14032
                                                       P         Concentrate      1:25
                  Pretreat.:    Citrate                                                     1 ml    501-14034
                  Status:       RUO

                  Apo-1 (Fas)
                  Please refer to CD95.

                  APP
                  Please refer to Amyloid Beta Precursor Protein.

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Arginase-1

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                       0.1 ml                   501-19280
Pretreat.:         Citrate                                P, WB              Concentrate                        1:100                      0.5 ml                    501-19282

                                                                                                                                                                                                                                                      Antibodies
Status:            RUO
                                                                                                                                             1 ml                    501-19284

Arginase-1

Clone:             SP156
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                       0.1 ml                    501-4560
Pretreat.:         EDTA                                      P               Concentrate                        1:100                      0.5 ml                     501-4562
Status:            RUO
                                                                                                                                             1 ml                     501-4564

ATRX

Clone:             60.1
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU                                  P, EL, WB             Concentrate                       1:200                        50 µg                     101-0630
Pretreat.:         Citrate
Status:            RUO

B-cells
Please refer to CD19, CD20, CD23, CD45RA, CD74, CD79a, pan B Cocktail, PAX.

Bax

Clone:             SP47
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                       0.1 ml                    502-3470
Pretreat.:         Citrate                                   P               Concentrate                        1:50                       0.5 ml                     502-3472
Status:            RUO
                                                                                                                                             1 ml                     502-3474

BCL1
Please refer to Cyclin D1.

BCL2

Clone:             E17
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                        6 ml                      RBG016
                                                                            Ready-to-use                           -
Pretreat.:         Citrate                                                                                                                  16 ml                      BRB055
Status:            CE/IVD                                  F, P
                                                                                                                                           0.5 ml                    RBK016-05
                                                                             Concentrate                   1:25 - 1:100
                                                                                                                                             1 ml                      RBK016

Reactivity: BV = Cow; CH = Chicken; DG = Dog; FE = Cat; FG = Frog, GT  = Goat; GP = Guinea pig; HM = Hamster; HS = Horse; HU = Human; MO = Monkey; MS = Mouse; PG = Pig; RB = Rabbit; RT = Rat; SH = Sheep; XE = Xenopus; ZF = Zebra fish a. o. = and others
Method: EL = ELISA; F = frozen sections IHC; FL = Flow Cytometry; IF = Immunofluorescense; IP = Immunoprecipitation; P = paraffin section IHC; WB = Western Blot
Status:     CE/IVD = for in vitro diagnostic use; RUO = Research use only                                                                                                                                                                      13
BCL6

                  Clone:        SP155
                                                    Method     Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                                                          0.1 ml   502-4550
                  Pretreat.:    Citrate              P, FL   Concentrate       1:100        0.5 ml   502-4552
Antibodies

                  Status:       RUO
                                                                                             1 ml    502-4554

                  Beta Catenin
                  Please refer to Catenin (beta).

                  BOB-1

                  Clone:        SP92
                                                    Method     Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                                                          0.1 ml   502-3920
                  Pretreat.:    Citrate              P, WB   Concentrate       1:100        0.5 ml   502-3922
                  Status:       RUO
                                                                                             1 ml    502-3924

                  BRST-2
                  Please refer to GCDFP-15.

                  C3d (Complement factor)

                  Clone:        polyclonal
                                                    Method     Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                           Ready-to-use         -          6 ml     RBG034
                                                     F, P
                  Pretreat.:    Citrate                      Concentrate    1:100-1:500     0.5 ml   RBK034-05
                  Status:       CE/IVD

                  C4d (Complement factor)

                  Clone:        A24-T
                                                    Method     Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                           Ready-to-use         -          6 ml     RBG061
                                                      P
                  Pretreat.:    Citrate                      Concentrate    1:100 - 1:200   0.5 ml   RBK061-05
                  Status:       CE/IVD

                  c-erbB1
                  Please refer to EGFr.

                  c-erbB2
                  Please refer to HER2.

                  c-erbB3
                  Please refer to HER3.

             14                                                                                                  www.zytomed-systems.com
CA 9 (Carbonic Anhydrase 9)

Clone:             SP106
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                      0.5 ml                     503-4062
                                                          P, WB              Concentrate                        1:100
Pretreat.:         Citrate                                                                                                                   1 ml                     503-4064

                                                                                                                                                                                                                                                      Antibodies
Status:            RUO

CA 15-3 Antigen
Please refer to MUC1.

CA 19-9 Antigen (Colon)

Clone:             121SLE
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU                                                       Ready-to-use                           -                         6 ml                      MSG094
                                                             P
Pretreat.:         Citrate                                                   Concentrate                    1:25 - 1:50                    0.5 ml                   MSK094-05
Status:            CE/IVD

CA 125

Clone:             Ov185:1
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU                                        P              Ready-to-use                           -                         6 ml                      MSG110
Pretreat.:         Citrate
Status:            RUO

Cadherin
Please refer to E-Cadherin, N-Cadherin und Ksp-Cadherin.

Cadherin 17

Clone:             1H3
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU                                                       Ready-to-use                           -                         6 ml                      MSG105
                                                             P
Pretreat.:         EDTA                                                      Concentrate                  1:100 - 1:200                    0.5 ml                    MSK105-05
Status:            CE/IVD

Cadherin 17

Clone:             SP183
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                       0.1 ml                    503-4830
Pretreat.:         EDTA                                      P               Concentrate                        1:100                      0.5 ml                     503-4832
Status:            RUO
                                                                                                                                             1 ml                     503-4834

Reactivity: BV = Cow; CH = Chicken; DG = Dog; FE = Cat; FG = Frog, GT  = Goat; GP = Guinea pig; HM = Hamster; HS = Horse; HU = Human; MO = Monkey; MS = Mouse; PG = Pig; RB = Rabbit; RT = Rat; SH = Sheep; XE = Xenopus; ZF = Zebra fish a. o. = and others
Method: EL = ELISA; F = frozen sections IHC; FL = Flow Cytometry; IF = Immunofluorescense; IP = Immunoprecipitation; P = paraffin section IHC; WB = Western Blot
Status:     CE/IVD = for in vitro diagnostic use; RUO = Research use only                                                                                                                                                                      15
Cadherin (Pan)

                  Clone:        polyclonal
                                                Method     Format        Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU               F, P    Concentrate       1:100        1 ml    503-2364
                  Pretreat.:    Citrate
Antibodies

                  Status:       RUO

                  Calcitonin

                  Clone:      SP17
                                                Method     Format        Dilution      Amount    Cat. No.
                  Host:       Rabbit
                  Reactivity: HU, MS, RT, DG,                                          0.5 ml   RBK038-05
                                                 F, P    Concentrate       1:100
                              PG, HS, SH                                                1 ml     RBK038
                  Pretreat.: Citrate
                  Status:     RUO

                  Caldesmon

                  Clone:        E-89
                                                Method     Format        Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                       Ready-to-use        -          6 ml     RBG040
                                                 F, P
                  Pretreat.:    Citrate                  Concentrate    1:25 - 1:100   0.5 ml   RBK040-05
                  Status:       CE/IVD

                  CALLA
                  Please refer to CD10.

                  Calpain

                  Clone:        SP81
                                                Method     Format        Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                P      Concentrate       1:100        1 ml    503-3814
                  Pretreat.:    Citrate
                  Status:       RUO

                  Calpastatin

                  Clone:        SP82
                                                Method     Format        Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                P      Concentrate       1:100        1 ml    503-3824
                  Pretreat.:    Citrate
                  Status:       RUO

                  Calponin-1

                  Clone:        EP789Y
                                                Method     Format        Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                       Ready-to-use        -          6 ml     RBG041
                                                 F, P
                  Pretreat.:    Citrate                  Concentrate    1:50 - 1:200   0.5 ml   RBK041-05
                  Status:       CE/IVD

             16                                                                                             www.zytomed-systems.com
Calretinin

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU, MS                                                                                                                    6 ml                      RBG003
                                                                            Ready-to-use                           -
Pretreat.:         Citrate                                                                                                                  16 ml                      BRB022

                                                                                                                                                                                                                                                      Antibodies
Status:            CE/IVD                                    P
                                                                                                                                           0.5 ml                    RBK003-05
                                                                             Concentrate                  1:100 - 1:200
                                                                                                                                             1 ml                      RBK003

Carbonic Anhydrase IX (CA IX)
Please refer to CA 9.

Carcinoembryonic Antigen
Please refer to CEA.

Caspase-3, cleaved (CPP32)

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU, MS, RT                                P               Concentrate                  1:50 - 1:200                     0.5 ml                   RBK009-05
Pretreat.:         Citrate
Status:            RUO

Catenin (beta)

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                        P              Ready-to-use                           -                         7 ml                     503-2261
Pretreat.:         Citrate                                                                                                                  0.1 ml                    503-2260
Status:            RUO
                                                          P, WB              Concentrate                       1:250                       0.5 ml                     503-2262

                                                                                                                                             1 ml                     503-2264

Catenin delta
Please refer to p120.

Cathepsin D

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                      F, P              Concentrate                        1:50                         1 ml                     503-2824
Pretreat.:         Citrate
Status:            RUO

Reactivity: BV = Cow; CH = Chicken; DG = Dog; FE = Cat; FG = Frog, GT  = Goat; GP = Guinea pig; HM = Hamster; HS = Horse; HU = Human; MO = Monkey; MS = Mouse; PG = Pig; RB = Rabbit; RT = Rat; SH = Sheep; XE = Xenopus; ZF = Zebra fish a. o. = and others
Method: EL = ELISA; F = frozen sections IHC; FL = Flow Cytometry; IF = Immunofluorescense; IP = Immunoprecipitation; P = paraffin section IHC; WB = Western Blot
Status:     CE/IVD = for in vitro diagnostic use; RUO = Research use only                                                                                                                                                                      17
CD1a

                  Clone:        EP3622
                                                  Method       Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                           Ready-to-use         -          6 ml     RBG045
                                                    F, P
                  Pretreat.:    Citrate or EDTA              Concentrate    1:25 - 1:100    0.5 ml   RBK045-05
Antibodies

                  Status:       CE/IVD

                  CD3

                  Clone:        polyclonal
                                                  Method       Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                                                           6 ml     RBG015
                                                             Ready-to-use         -
                  Pretreat.:    Citrate                                                      16 ml    BRB063
                  Status:       CE/IVD              F, P
                                                                                            0.5 ml   RBK015-05
                                                             Concentrate    1:200 - 1:400
                                                                                             1 ml     RBK015

                  CD3

                  Clone:        SP7
                                                  Method       Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU, MS                                                       6 ml     RBG024
                                                    F, P     Ready-to-use         -
                  Pretreat.:    Citrate                                                      16 ml   BRB041*
                  Status:       RUO, *CE/IVD
                                                                                            0.5 ml   RBK024-05
                                                  F, P, WB   Concentrate    1:150 - 1:200
                                                                                             1 ml     RBK024

                  CD4

                  Clone:        SP35
                                                  Method       Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                  F, P     Ready-to-use         -          16 ml    BRB042
                  Pretreat.:    Citrate
                  Status:       CE/IVD

                  CD4

                  Clone:        SP35
                                                  Method       Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                  F, P     Concentrate        1:50         1 ml    503-3354
                  Pretreat.:    Citrate or EDTA
                  Status:       RUO

                  CD5

                  Clone:        SP19
                                                  Method       Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                  F, P     Concentrate    1:50 - 1:100    0.5 ml   RBK023-05
                  Pretreat.:    Citrate
                  Status:       RUO

             18                                                                                                  www.zytomed-systems.com
CD5

Clone:             4C7
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU                                                       Ready-to-use                           -                         6 ml                      MSG120
                                                           F, P
Pretreat.:         Citrate                                                   Concentrate                        1:100                      0.5 ml                    MSK120-05

                                                                                                                                                                                                                                                      Antibodies
Status:            CE/IVD

CD7

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                       0.1 ml                   503-18930
Pretreat.:         Citrate                                   P               Concentrate                       1:200                       0.5 ml                    503-18932
Status:            RUO
                                                                                                                                             1 ml                    503-18934

CD8

Clone:             SP16
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                      F, P             Ready-to-use                           -                        16 ml                      BRB036
Pretreat.:         Citrate
Status:            CE/IVD

CD8

Clone:             C8/144B
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU                                                       Ready-to-use                           -                         6 ml                      MSG011
Pretreat.:         EDTA                                    F, P                                                                            0.5 ml                    MSK011-05
Status:            CE/IVD                                                    Concentrate                        1:100
                                                                                                                                             1 ml                      MSK011

CD10 (CALLA)

Clone:             56C6
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU, RT                                                                                                                    6 ml                      MSG070
                                                                            Ready-to-use                           -
Pretreat.:         Citrate                                                                                                                  16 ml                      BMS043
Status:            CE/IVD                                  F, P
                                                                                                                                           0.5 ml                   MSK070-05
                                                                             Concentrate                    1:25 - 1:50
                                                                                                                                             1 ml                      MSK070

CD10 (CALLA)

Clone:             SP67
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                       0.1 ml                    503-3670
Pretreat.:         EDTA                                   P, WB              Concentrate                        1:100                      0.5 ml                     503-3672
Status:            RUO
                                                                                                                                             1 ml                     503-3674

Reactivity: BV = Cow; CH = Chicken; DG = Dog; FE = Cat; FG = Frog, GT  = Goat; GP = Guinea pig; HM = Hamster; HS = Horse; HU = Human; MO = Monkey; MS = Mouse; PG = Pig; RB = Rabbit; RT = Rat; SH = Sheep; XE = Xenopus; ZF = Zebra fish a. o. = and others
Method: EL = ELISA; F = frozen sections IHC; FL = Flow Cytometry; IF = Immunofluorescense; IP = Immunoprecipitation; P = paraffin section IHC; WB = Western Blot
Status:     CE/IVD = for in vitro diagnostic use; RUO = Research use only                                                                                                                                                                      19
CD11c

                  Clone:        5D11
                                                  Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                         Ready-to-use         -          6 ml     MSG093
                                                    P
                  Pretreat.:    Citrate or EDTA            Concentrate    1:50 - 1:100    0.5 ml   MSK093-05
Antibodies

                  Status:       CE/IVD

                  CD13

                  Clone:        SP182
                                                  Method     Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                                                        0.1 ml   503-4820
                  Pretreat.:    EDTA               P, FL   Concentrate       1:100        0.5 ml   503-4822
                  Status:       RUO
                                                                                           1 ml    503-4824

                  CD14

                  Clone:        EPR3653
                                                  Method     Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                 F, P    Concentrate    1:50 - 1:200    0.5 ml   RBK033-05
                  Pretreat.:    Citrate
                  Status:       CE/IVD

                  CD15

                  Clone:        MMA + BY87
                                                  Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                                                         6 ml     MSG108
                                                           Ready-to-use         -
                  Pretreat.:    Citrate             P                                      16 ml   BMS066*
                  Status:       CE/IVD, *RUO
                                                           Concentrate    1:50 - 1:100    0.5 ml   MSK108-05

                  CD16a

                  Clone:        SP189
                                                  Method     Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                  P      Ready-to-use         -          7 ml    506-4891
                  Pretreat.:    EDTA                                                      0.1 ml   506-4890
                  Status:       RUO
                                                   P, WB   Concentrate       1:100        0.5 ml   506-4892

                                                                                           1 ml    506-4894

                  CD19

                  Clone:        LE-CD19
                                                  Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                  P      Concentrate    1:100 - 1:200   0.5 ml   MSK043-05
                  Pretreat.:    Citrate
                  Status:       RUO

             20                                                                                                www.zytomed-systems.com
CD20

Clone:             L26
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU                                                                                                                        6 ml                      MSG008
                                                                            Ready-to-use                           -
Pretreat.:         optional: Citrate                                                                                                        16 ml                      BMS003

                                                                                                                                                                                                                                                      Antibodies
Status:            CE/IVD                                  F, P
                                                                                                                                           0.5 ml                   MSK008-05
                                                                             Concentrate                  1:100 - 1:200
                                                                                                                                             1 ml                      MSK008

CD20

Clone:             SP32
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                      0.5 ml                    RBK030-05
                                                             P               Concentrate                        1:100
Pretreat.:         -                                                                                                                         1 ml                      RBK030
Status:            RUO

CD21

Clone:             EP3093
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                       Ready-to-use                           -                         6 ml                      RBG036
                                                           F, P
Pretreat.:         Citrate                                                   Concentrate                  1:50 - 1:200                     0.5 ml                    RBK036-05
Status:            CE/IVD

CD22

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                       0.1 ml                   503-19020
Pretreat.:         Citrate                                   P               Concentrate                       1:200                       0.5 ml                    503-19022
Status:            RUO
                                                                                                                                             1 ml                    503-19024

CD23

Clone:             SP163
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                      0.5 ml                     503-4632
                                                          P, WB              Concentrate                        1:50
Pretreat.:         Citrate                                                                                                                   1 ml                     503-4634
Status:            RUO

CD25

Clone:             SP176
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU, MS, RT                                                                                                               0.1 ml                    503-4760
Pretreat.:         EDTA                                   P, WB              Concentrate                       1:200                       0.5 ml                     503-4762
Status:            RUO
                                                                                                                                             1 ml                     503-4764

Reactivity: BV = Cow; CH = Chicken; DG = Dog; FE = Cat; FG = Frog, GT  = Goat; GP = Guinea pig; HM = Hamster; HS = Horse; HU = Human; MO = Monkey; MS = Mouse; PG = Pig; RB = Rabbit; RT = Rat; SH = Sheep; XE = Xenopus; ZF = Zebra fish a. o. = and others
Method: EL = ELISA; F = frozen sections IHC; FL = Flow Cytometry; IF = Immunofluorescense; IP = Immunoprecipitation; P = paraffin section IHC; WB = Western Blot
Status:     CE/IVD = for in vitro diagnostic use; RUO = Research use only                                                                                                                                                                      21
CD30 (Ki-1)

                  Clone:        Ber-H2
                                                    Method     Format        Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                           Ready-to-use        -          6 ml     MSG061
                  Pretreat.:    Citrate              F, P                                  0.5 ml   MSK061-05
Antibodies

                  Status:       CE/IVD                       Concentrate    1:40 - 1:80
                                                                                            1 ml     MSK061

                  CD31 (PECAM-1)

                  Clone:        JC70
                                                    Method     Format        Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                                                          6 ml     MSG091
                                                             Ready-to-use        -
                  Pretreat.:    Citrate                                                     16 ml   BMS044*
                  Status:       RUO, *CE/IVD         F, P
                                                                                           0.5 ml   MSK091-05
                                                             Concentrate    1:50 - 1:200
                                                                                            1 ml     MSK091

                  CD31 (PECAM-1)

                  Clone:        SP38
                                                    Method     Format        Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU, MS, PG                   Ready-to-use        -          7 ml    503-3381
                                                      P
                  Pretreat.:    Citrate                      Concentrate       1:50         1 ml    503-3384
                  Status:       RUO

                  CD34

                  Clone:        QBEnd/10
                                                    Method     Format        Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                           Ready-to-use        -          16 ml   BMS045*
                  Pretreat.:    optional: Citrate    F, P                                  0.5 ml   MSK122-05
                  Status:       RUO, *CE/IVD                 1:50 - 1:200   1:50 - 1:200
                                                                                            1 ml     MSK122

                  CD38

                  Clone:        SP149
                                                    Method     Format        Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                    P      Ready-to-use        -          7 ml    503-4491
                  Pretreat.:    Citrate                                                    0.1 ml   503-4490
                  Status:       RUO
                                                     P, FL   Concentrate       1:100       0.5 ml   503-4492

                                                                                            1 ml    503-4494

                  CD42b

                  Clone:        SP202
                                                    Method     Format        Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                           Ready-to-use        -          7 ml    503-5021
                  Pretreat.:    EDTA                                                       0.1 ml   503-5020
                  Status:       RUO                   P
                                                             Concentrate       1:100       0.5 ml   503-5022

                                                                                            1 ml    503-5024

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CD42b

Clone:             SP219
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                       0.1 ml                    503-5190
Pretreat.:         Citrat                                  P, FL             Concentrate                        1:100                      0.5 ml                     503-5192

                                                                                                                                                                                                                                                      Antibodies
Status:            RUO
                                                                                                                                             1 ml                     503-5194

CD43

Clone:             DF-T1
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU, RT                                                                                                                  0.5 ml                   MSK065-05
                                                           F, P              Concentrate                   1:50 - 1:100
Pretreat.:         Citrate (optional)                                                                                                        1 ml                      MSK065
Status:            RUO

CD45 (LCA)

Clone:             PD7/26+2B11
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU                                                                                                                        6 ml                      MSG054
                                                                            Ready-to-use                           -
Pretreat.:         Citrate                                                                                                                  16 ml                      BMS046
Status:            CE/IVD                                  F, P
                                                                                                                                           0.5 ml                   MSK054-05
                                                                             Concentrate                   1:50 - 1:100
                                                                                                                                             1 ml                      MSK054

CD56

Clone:             RCD56
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU, MS, RT                                                                                                                6 ml                      RBG050
                                                             P              Ready-to-use                           -
Pretreat.:         EDTA                                                                                                                     16 ml                      BRB039
Status:            CE/IVD
                                                                                                                                           0.5 ml                    RBK050-05
                                                          P, WB              Concentrate                  1:100 - 1:500
                                                                                                                                             1 ml                      RBK050

CD61

Clone:             2f2
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU                                                       Ready-to-use                           -                         6 ml                      MSG086
Pretreat.:         EDTA                                    F, P                                                                            0.5 ml                   MSK086-05
Status:            CE/IVD                                                    Concentrate                   1:25 - 1:100
                                                                                                                                             1 ml                      MSK086

CD63

Clone:             SPM524
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU                                      F, P              Concentrate                       1:200                         1 ml                     503-17514
Pretreat.:         Citrate
Status:            RUO

Reactivity: BV = Cow; CH = Chicken; DG = Dog; FE = Cat; FG = Frog, GT  = Goat; GP = Guinea pig; HM = Hamster; HS = Horse; HU = Human; MO = Monkey; MS = Mouse; PG = Pig; RB = Rabbit; RT = Rat; SH = Sheep; XE = Xenopus; ZF = Zebra fish a. o. = and others
Method: EL = ELISA; F = frozen sections IHC; FL = Flow Cytometry; IF = Immunofluorescense; IP = Immunoprecipitation; P = paraffin section IHC; WB = Western Blot
Status:     CE/IVD = for in vitro diagnostic use; RUO = Research use only                                                                                                                                                                      23
CD66
                  Please refer to CEA.

                  CD68
Antibodies

                  Clone:        KP1
                                             Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                    Ready-to-use         -          6 ml     MSG055
                  Pretreat.:    Citrate       F, P                                   0.5 ml   MSK055-05
                  Status:       CE/IVD                Concentrate    1:50 - 1:100
                                                                                      1 ml     MSK055

                  CD79a

                  Clone:        JCB117
                                             Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                                                    6 ml     MSG036
                                                      Ready-to-use         -
                  Pretreat.:    Citrate                                               16 ml    BMS005
                  Status:       CE/IVD        F, P
                                                                                     0.5 ml   MSK036-05
                                                      Concentrate    1:50 - 1:100
                                                                                      1 ml     MSK036

                  CD79a

                  Clone:        SP18
                                             Method     Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                    Ready-to-use         -          6 ml     RBG029
                  Pretreat.:    Citrate       F, P                                   0.5 ml   RBK029-05
                  Status:       RUO                   Concentrate    1:100 - 1:200
                                                                                      1 ml     RBK029

                  CD79b

                  Clone:        SP240
                                             Method     Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                                                   0.1 ml   503-5400
                  Pretreat.:    Citrate       P, WB   Concentrate       1:100        0.5 ml   503-5402
                  Status:       RUO
                                                                                      1 ml    503-5404

                  CD95 (Fas, Apo-1)

                  Clone:        polyclonal
                                             Method     Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU            F, P    Concentrate        1:60         1 ml    503-2504
                  Pretreat.:    Citrate
                  Status:       RUO

             24                                                                                           www.zytomed-systems.com
CD95L (Fas Ligand)

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU, MS, RT                           F, P, WB             Concentrate                        1:100                        1 ml                     506-2714
Pretreat.:         Citrate

                                                                                                                                                                                                                                                      Antibodies
Status:            RUO

CD99

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                       0.1 ml                    503-3390
Pretreat.:         Citrate                                 F, P              Concentrate                       1:200                       0.5 ml                     503-3392
Status:            RUO
                                                                                                                                             1 ml                     503-3394

CD105 (Endoglin, TGF-beta1/3-Receptor)

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                      F, P              Concentrate                        1:50                         1 ml                     503-4234
Pretreat.:         Citrate
Status:            RUO

CD117/c-kit

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                       Ready-to-use                           -                         7 ml                      503-1441
Pretreat.:         Citrate                                                                                                                  0.1 ml                    503-1440
Status:            RUO                                     F, P
                                                                             Concentrate                        1:100                      0.5 ml                     503-1442

                                                                                                                                             1 ml                     503-1444

CD138 (Syndecan-1)

Clone:             B-A38
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU, PG                                                   Ready-to-use                           -                         6 ml                      MSG063
Pretreat.:         Citrate                                 F, P                                                                            0.5 ml                   MSK063-05
Status:            CE/IVD                                                    Concentrate                       1:200
                                                                                                                                             1 ml                      MSK063

CD140a
Please refer to PDGFr-alpha.

CD140b
Please refer to PDGFr-beta.

Reactivity: BV = Cow; CH = Chicken; DG = Dog; FE = Cat; FG = Frog, GT  = Goat; GP = Guinea pig; HM = Hamster; HS = Horse; HU = Human; MO = Monkey; MS = Mouse; PG = Pig; RB = Rabbit; RT = Rat; SH = Sheep; XE = Xenopus; ZF = Zebra fish a. o. = and others
Method: EL = ELISA; F = frozen sections IHC; FL = Flow Cytometry; IF = Immunofluorescense; IP = Immunoprecipitation; P = paraffin section IHC; WB = Western Blot
Status:     CE/IVD = for in vitro diagnostic use; RUO = Research use only                                                                                                                                                                      25
CD163

                  Clone:        SP96
                                                     Method     Format      Dilution   Amount   Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                     P      Concentrate    1:100      1 ml    503-3964
                  Pretreat.:    EDTA
Antibodies

                  Status:       RUO

                  CD169

                  Clone:        SP213
                                                     Method     Format      Dilution   Amount   Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                                                     0.1 ml   519-5130
                  Pretreat.:    Citrate                P      Concentrate    1:100     0.5 ml   519-5132
                  Status:       RUO
                                                                                        1 ml    519-5134

                  CD178
                  Please refer to CD95L.

                  CD207
                  Please refer to Langerin.

                  CD227
                  Please refer to MUC1 und EMA.

                  CD246
                  Please refer to ALK.

                  CD274
                  Please refer to PD-L1.

                  CD278

                  Clone:        SP98
                                                     Method     Format      Dilution   Amount   Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU, MS                                                 0.1 ml   509-3980
                  Pretreat.:    EDTA                   P      Concentrate    1:100     0.5 ml   509-3982
                  Status:       RUO
                                                                                        1 ml    509-3984

                  CD279
                  Please refer to PD1.

                  CD308
                  Please refer to VEGFr-1 (Flt-1).

             26                                                                                            www.zytomed-systems.com
CD309
Please refer to VEGFr-2 (Flk-1).

CD310

                                                                                                                                                                                                                                                      Antibodies
Please refer to VEGFr-3 (Flt-4).

CD324
Please refer to E-Cadherin.

CD326
Please refer to Epithelial Specific Antigen.

CD331 - CD333
Please refer to FGFR1 bis FGFR3.

CD380
Please refer to HER2.

CDH17
Please refer to Cadherin 17.

Cdk4 (Cyclin dependent Kinase)

Clone:             DCS-31.2
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU, MS, RT                          F, P, WB,             Concentrate                  1:100 - 1:250                    100 µg                     603-1840
Pretreat.:         Citrate
Status:            RUO

CDw325
Please refer to N-Cadherin.

CDX-2

Clone:             EPR2764Y
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                        6 ml                      RBG019
                                                                            Ready-to-use                           -
Pretreat.:         Citrate                                                                                                                  16 ml                      BRB028
Status:            CE/IVD                                  F, P
                                                                                                                                           0.5 ml                    RBK019-05
                                                                             Concentrate                   1:50 - 1:100
                                                                                                                                             1 ml                      RBK019

Reactivity: BV = Cow; CH = Chicken; DG = Dog; FE = Cat; FG = Frog, GT  = Goat; GP = Guinea pig; HM = Hamster; HS = Horse; HU = Human; MO = Monkey; MS = Mouse; PG = Pig; RB = Rabbit; RT = Rat; SH = Sheep; XE = Xenopus; ZF = Zebra fish a. o. = and others
Method: EL = ELISA; F = frozen sections IHC; FL = Flow Cytometry; IF = Immunofluorescense; IP = Immunoprecipitation; P = paraffin section IHC; WB = Western Blot
Status:     CE/IVD = for in vitro diagnostic use; RUO = Research use only                                                                                                                                                                      27
CEA

                  Clone:        Col-1
                                                     Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                                                            6 ml     MSG022
                                                              Ready-to-use         -
                  Pretreat.:    -                                                             16 ml    BMS029
Antibodies

                  Status:       CE/IVD                F, P
                                                                                             0.5 ml   MSK022-05
                                                              Concentrate    1:100 - 1:200
                                                                                              1 ml     MSK022

                  Chromogranin A

                  Clone:        LK2H10
                                                     Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU, PG                                                        6 ml     MSG062
                                                              Ready-to-use         -
                  Pretreat.:    -                                                             16 ml    BMS018
                  Status:       CE/IVD                F, P
                                                                                             0.5 ml   MSK062-05
                                                              Concentrate    1:200 - 1:400
                                                                                              1 ml     MSK062

                  cKit
                  Please refer to CD117.

                  Claudin 1

                  Clone:        polyclonal
                                                     Method     Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU, MS, RT                    Ready-to-use         -          7 ml     503-3411
                                                      F, P
                  Pretreat.:    Citrate                       Concentrate       1:200         1 ml     503-3414
                  Status:       RUO

                  Claudin 4

                  Clone:        polyclonal
                                                     Method     Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU, MS                                                       0.1 ml   503-3980
                  Pretreat.:    Citrate                P      Concentrate       1:200        0.5 ml   503-3982
                  Status:       RUO
                                                                                              1 ml    503-3984

                  Claudin 7

                  Clone:        polyclonal
                                                     Method     Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU, MS, RT            F, P    Concentrate       1:200         1 ml    503-10594
                  Pretreat.:    Citrate
                  Status:       RUO

                  CMV
                  Please refer to Cytomegalovirus.

             28                                                                                                   www.zytomed-systems.com
Connexin 43

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU, MS, RT                        F, P, WB, IP            Concentrate                        1:50                         1 ml                     503-2744
Pretreat.:         Citrate

                                                                                                                                                                                                                                                      Antibodies
Status:            RUO

COX-1

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                      F, P              Concentrate                        1:100                        1 ml                     503-14314
Pretreat.:         Citrate
Status:            RUO

COX-2

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU, MS, RT                              F, P             Ready-to-use                           -                         7 ml                     503-3031
Pretreat.:         Citrate                           F, P, WB, IP            Concentrate                        1:100                        1 ml                     503-3034
Status:            RUO

CTLA4

Clone:             UMAB249
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU                                                       Ready-to-use                           -                         6 ml                      MSG116
                                                             P
Pretreat.:         Citrate                                                   Concentrate                        1:100                      0.5 ml                    MSK116-05
Status:            CE/IVD

CUL-1, Cullin 1

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                       0.1 ml                    503-3790
                                                             P               Concentrate                        1:50
Pretreat.:         Citrate                                                                                                                 0.5 ml                     503-3792
Status:            RUO

Cyclin D1

Clone:             SP4
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU, MS, RT                              F, P              Concentrate                   1:50 - 1:100                    0.5 ml                    RBK025-05
Pretreat.:         Citrate or EDTA
Status:            RUO

Cyclin D3

Clone:             SP207
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                                                                                       0.1 ml                    503-5070
Pretreat.:         -                                      P, WB              Concentrate                        1:100                      0.5 ml                     503-5072
Status:            RUO
                                                                                                                                             1 ml                     503-5074

Reactivity: BV = Cow; CH = Chicken; DG = Dog; FE = Cat; FG = Frog, GT  = Goat; GP = Guinea pig; HM = Hamster; HS = Horse; HU = Human; MO = Monkey; MS = Mouse; PG = Pig; RB = Rabbit; RT = Rat; SH = Sheep; XE = Xenopus; ZF = Zebra fish a. o. = and others
Method: EL = ELISA; F = frozen sections IHC; FL = Flow Cytometry; IF = Immunofluorescense; IP = Immunoprecipitation; P = paraffin section IHC; WB = Western Blot
Status:     CE/IVD = for in vitro diagnostic use; RUO = Research use only                                                                                                                                                                      29
Cyclin Dependent Kinase
                  Please refer to Cdk.

                  Cyclooxygenase
Antibodies

                  Please refer to COX-1 und COX-2.

                  Cytokeratin 5 & 6

                  Clone:        D5/16B4
                                                     Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                                                            6 ml     MSG034
                                                              Ready-to-use         -
                  Pretreat.:    Citrate                                                       16 ml    BMS017
                  Status:       CE/IVD                F, P
                                                                                             0.5 ml   MSK034-05
                                                              Concentrate    1:50 - 1:100
                                                                                              1 ml     MSK034

                  Cytokeratin 5 & 14

                  Clone:        XM26+LL002
                                                     Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                                                            6 ml     MSG106
                                                              Ready-to-use         -
                  Pretreat.:    Citrate                                                       16 ml    BMS023
                  Status:       CE/IVD                F, P
                                                                                             0.5 ml   MSK106-05
                                                              Concentrated   1:50 - 1:100
                                                                                              1 ml     MSK106

                  Cytokeratin 6

                  Clone:        SP87
                                                     Method     Format         Dilution      Amount    Cat. No.
                  Host:         Rabbit
                  Reactivity:   HU                                                           0.1 ml   503-3870
                  Pretreat.:    Citrate               P, WB   Concentrate       1:200        0.5 ml   503-3872
                  Status:       RUO
                                                                                              1 ml    503-3874

                  Cytokeratin 7

                  Clone:        OV-TL 12/30
                                                     Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                                                            6 ml     MSG032
                                                              Ready-to-use         -
                  Pretreat.:    Citrate or                                                    16 ml    BMS030
                                Fast Enzyme           F, P
                                                                                             0.5 ml   MSK032-05
                  Status:       CE/IVD                        Concentrate    1:100 - 1:200
                                                                                              1 ml     MSK032

             30                                                                                                   www.zytomed-systems.com
Cytokeratin 8

Clone:             SP102
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                       Ready-to-use                           -                         7 ml                     503-4021
Pretreat.:         Citrate                                                                                                                  0.1 ml                    503-4020

                                                                                                                                                                                                                                                      Antibodies
Status:            RUO                                       P
                                                                             Concentrate                        1:100                      0.5 ml                     503-4022

                                                                                                                                             1 ml                     503-4024

Cytokeratin 8 & 18

Clone:             IVT2000
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU                                                       Ready-to-use                           -                         6 ml                      MSG035
Pretreat.:         Citrate or                                P                                                                             0.5 ml                   MSK035-05
                   Fast Enzyme                                               Concentrate                  1:100 - 1:200
                                                                                                                                             1 ml                      MSK035
Status:            RUO

Cytokeratin 10

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                        P               Concentrate                        1:100                       0.1 ml                   503-18980
Pretreat.:         EDTA
Status:            RUO

Cytokeratin 14

Clone:             SP53
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                        P               Concentrate                        1:100                        1 ml                     503-3534
Pretreat.:         Citrate
Status:            RUO

Cytokeratin 17

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                     P, WB              Concentrate                       1:200                         1 ml                    503-18924
Pretreat.:         EDTA
Status:            RUO

Cytokeratin 18

Clone:             DC-10
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU                                                       Ready-to-use                           -                         6 ml                      MSG016
Pretreat.:         Citrate or                              F, P                                                                            0.5 ml                   MSK016-05
                   Fast Enzyme                                               Concentrate                  1:100 - 1:200
                                                                                                                                             1 ml                      MSK016
Status:            RUO

Reactivity: BV = Cow; CH = Chicken; DG = Dog; FE = Cat; FG = Frog, GT  = Goat; GP = Guinea pig; HM = Hamster; HS = Horse; HU = Human; MO = Monkey; MS = Mouse; PG = Pig; RB = Rabbit; RT = Rat; SH = Sheep; XE = Xenopus; ZF = Zebra fish a. o. = and others
Method: EL = ELISA; F = frozen sections IHC; FL = Flow Cytometry; IF = Immunofluorescense; IP = Immunoprecipitation; P = paraffin section IHC; WB = Western Blot
Status:     CE/IVD = for in vitro diagnostic use; RUO = Research use only                                                                                                                                                                      31
Cytokeratin 19

                  Clone:        A53-B/A2.26
                                                  Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                         Ready-to-use         -          6 ml     MSG017
                  Pretreat.:    Citrate            F, P                                   0.5 ml   MSK017-05
Antibodies

                  Status:       CE/IVD                     Concentrate    1:200 - 1:300
                                                                                           1 ml     MSK017

                  Cytokeratin 20

                  Clone:        Ks20.8
                                                  Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                                                         6 ml     MSG119
                                                           Ready-to-use         -
                  Pretreat.:    proteolytic                                                16 ml    BMS037
                  Status:       CE/IVD              P
                                                                                          0.5 ml   MSK119-05
                                                           Concentrate     1:25 - 1:50
                                                                                           1 ml     MSK119

                  Cytokeratin Broad Spectrum

                  Clone:        AE1+AE3
                                                  Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU, MS, RT, DG                                             6 ml     MSG019
                                                           Ready-to-use         -
                  Pretreat.:    Citrate or                                                 16 ml    BMS006
                                Fast Enzyme        F, P
                                                                                          0.5 ml   MSK019-05
                  Status:       CE/IVD                     Concentrate    1:100 - 1:200
                                                                                           1 ml     MSK019

                  Cytokeratin (HMW)

                  Clone:        34betaE12
                                                  Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU, RB, DG                                                 6 ml     MSG027
                                                           Ready-to-use         -
                  Pretreat.:    Citrate, Pepsin                                            16 ml    BMS015
                                or Fast Enzyme     F, P
                                                                                          0.5 ml   MSK027-05
                  Status:       CE/IVD                     Concentrate     1:25 - 1:50
                                                                                           1 ml     MSK027

                  Cytokeratin (OSCAR)

                  Clone:        OSCAR
                                                  Method     Format         Dilution      Amount    Cat. No.
                  Host:         Mouse
                  Reactivity:   HU                         Ready-to-use         -          6 ml    Z-465-26-Y
                                                   F, P
                  Pretreat.:    Citrate                    Concentrate        1:40         1 ml    Z-465-01-Y
                  Status:       RUO

             32                                                                                                 www.zytomed-systems.com
Cytokeratin Pan

Clone:      KL1
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:       Mouse
Reactivity: HU, RT, MS, RB,                                                                                                                  6 ml                      MSG113
                                                                            Ready-to-use                           -
            FE, DG, ZF                                                                                                                      16 ml                      BMS056

                                                                                                                                                                                                                                                      Antibodies
Pretreat.: Citrate                                           P
                                                                                                                                           0.5 ml                    MSK113-05
Status:     CE/IVD                                                           Concentrate                        1:100
                                                                                                                                             1 ml                      MSK113

Cytokeratin Pan Plus (AE1 & AE3 & 5D3)

Clone:             AE1+AE3+5D3
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU, MS, RT                                                                                                                6 ml                      MSG098
                                                                            Ready-to-use                           -
Pretreat.:         Citrate, EDTA                             P                                                                              16 ml                      BMS057
                   or proteolytic
                                                                             Concentrate                   1:50 - 1:100                    0.5 ml                   MSK098-05
Status:            CE/IVD

Cytomegalovirus (CMV)

Clone:             DDG9+CCH2
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        CMV                                                      Ready-to-use                           -                         6 ml                      MSG121
                                                             P
Pretreat.:         Citrate                                                   Concentrate                    1:10 - 1:25                    0.5 ml                    MSK121-05
Status:            RUO

D2-40 (Lymphatic Endothelium Marker)
Please refer to Podoplanin.

Desmin

Clone:             D33
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Mouse
Reactivity:        HU, MS, RT                                                                                                                6 ml                      MSG053
                                                                            Ready-to-use                           -
Pretreat.:         Citrate                                                                                                                  16 ml                      BMS007
Status:            CE/IVD                                  F, P
                                                                                                                                           0.5 ml                   MSK053-05
                                                                             Concentrate                    1:25 - 1:50
                                                                                                                                             1 ml                      MSK053

DOG1

Clone:             polyclonal
                                                       Method                    Format                      Dilution                     Amount                       Cat. No.
Host:              Rabbit
Reactivity:        HU                                                       Ready-to-use                           -                         7 ml                     516-16711
                                                           F, P
Pretreat.:         Citrate                                                   Concentrate                        1:100                        1 ml                     516-16714
Status:            RUO

Reactivity: BV = Cow; CH = Chicken; DG = Dog; FE = Cat; FG = Frog, GT  = Goat; GP = Guinea pig; HM = Hamster; HS = Horse; HU = Human; MO = Monkey; MS = Mouse; PG = Pig; RB = Rabbit; RT = Rat; SH = Sheep; XE = Xenopus; ZF = Zebra fish a. o. = and others
Method: EL = ELISA; F = frozen sections IHC; FL = Flow Cytometry; IF = Immunofluorescense; IP = Immunoprecipitation; P = paraffin section IHC; WB = Western Blot
Status:     CE/IVD = for in vitro diagnostic use; RUO = Research use only                                                                                                                                                                      33
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