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NUTRA BLEND SALES REPRESENTATIVES WEST RON PRASKA CONTENT Western Regional Sales Mgr. (612) 309-2659 RPraska@nutrablend.net JOHN LOWHAM 04 OR, WA, ID, UT, MT (208) 740-0646 TECH TALK: ALLTECH JWLowham@nutrablend.net PREBIOTICS IN LIVESTOCK PRODUCTION SYSTEMS: A FUNCTIONAL ROLE FOR AL PEDERSON NATURAL CARBOHYDRATES MN, ND (715) 501-8009 07 APederson@nutrablend.net TECH TALK: CHR HANSEN SARAH WEBER CA, NV THE ROLE OF CATTLE MANAGEMENT IN THE BATTLE THE BEEF INDUSTRY FACES (559) 416-6612 AGAINST SALMONELLA Sweber@nutrablend.net 08 TECH TALK: KEMIN CENTRAL MATT HARPER MAKING HIGH-QUALITY TMR: TIPS TO PROTECT FINISHED FEED Central Regional Sales Mgr. (515) 473-0240 13 MGHarper@nutrablend.net TECH TALK: ARM & HAMMER TIFFANY BUCHER CONTROLLING PATHOGENS ON DAIRIES WITH A WHOLE FARM APPROACH KS, NE, SD (612) 239-3511 15 tmbucher@nutrablend.net TECH TALK: ZINPRO JOHN BUDD OK, E. TX, Pet Food ZINPRO PERFORMANCE MINERALS® REDUCE PRODUCTION COSTS AND INCREASE (580) 504-1120 SOW LIVABILITY JMBudd@nutrablend.net 17 TECH TALK: DIAMOND V JOHN CHARLEY Iowa MANAGEMENT TIP TOPIC: BUILD A HEALTHY RUMEN ENVIRONMENT (515) 571-0393 JACharley@nutrablend.net 18 TECH TALK: BALCHEM JOE PIERSON AR, MO, LA BALCHEM RESEARCH SUMMARY: STUDY MEASURES METHYL DONOR CONTENT (417) 312-7388 JNPierson@nutrablend.net OF KEY COMMODITIES 20 HEATH WILLIAMSON TECH TALK: ADISSEO CO, E. AZ, NM, W. TX (417) 389-2654 DON’T LET MYCOTOXINS TANK THE PROFITABILITY OF YOUR DAIRY FARM RHWilliamson@nutrablend.net JUSTIN WOOD 21 WI, N.W. IL NUTRA BLEND CUSTOMER REWARDS POINTS (715) 607-1394 JAWood@nutrablend.net SEPTEMBER EAST WAYNE PAGEL Eastern Regional Sales Mgr. (606) 584-0603 NUTRA BLEND, LLC WWPagel@nutrablend.net 3200 EAST 2ND STREET TIM GOLD NEOSHO, MO 64850 MI, IN, OH (201) 741-9864 417-451-6111 TGold@nutrablend.net WWW.NUTRABLEND.NET PETER HAUSSER NY, VT, CT, MA, ME, NH, RI QUESTIONS? CONTACT MARKETING AT MARKETING@NUTRABLEND.NET (607) 768-0905 PHausser@nutrablend.net RANDY HOLLIMAN S.IL, TN, KY CUSTOMER SERVICE (615) 218-1420 REPRESENTATIVES RKHolliman@nutrablend.net RICK KOLB EAST CENTRAL PA, NJ, DE, MD, VA, WV Christine Whittier 802-988-4474 Jane Imthurn 417-455-7191 Kris Franklin 888-470-5519 (717) 951-0672 Mark Frkovich 888-469-4699 Ryan Jinks 855-920-0154 RKolb@nutrablend.net WEST Clayton Adams 888-470-5517 Jamie McClain 888-366-6467, ext 5 BILLY NORRELL Bernadette Hernandez 559-661-6161 Ann Brungardt 888-366-6467, ext 3 Melinda Newell 888-470-3128 MS, AL, GA, SC, NC, FL Jennie Valdez 559-661-6161 Shane Bennett 888-470-2635 Kristy Teague 888-366-6467, ext 4 (601) 559-9799 Ramon Pimentel 559-661-6161 Allen Dorsey 800-657-5657 WHNorrell@nutrablend.net 2
PREBIOTICS IN LIVESTOCK PRODUCTION SYSTEMS: A FUNCTIONAL ROLE FOR NATURAL CARBOHYDRATES writer // Richard Murphy, Ph.D./ Research Director / Alltech Bioscience Centre, Dunboyne, Co. Meath Targeted nutrition, starting with the structure, enabling the feed additive to act as of Bio-Mos® 2 enables the gut to “police” development and maintenance of the a decoy, providing a first level of protection itself through promotion of microbial intestine, results in the production of stronger, by blocking attachments to intestinal cells diversity, thereby reducing issues associated healthier animals. For many years now, it has (Jacques and Newman, 1994). with pathogen colonization. been known that the use of carbohydrates isolated from the cell wall of specific yeast Distinct from original first-generation MOS A drawback of antibiotics is their non-specific strains plays a central role in modulating products such as Bio-Mos, the second- effect on the microbiome and the reduction immune responses, preserving gut tissue generation Bio-Mos® 2 is best described in overall microbial diversity noted with integrity and eliminating pathogens from the as a natural growth permitter. Bio-Mos® 2, their use. Given the ability of Bio-Mos® 2 to intestine. a bioactive mannose-rich fraction (MRF), is enhance the overall gut microfloral diversity, derived from the outer cell wall of a specific it is an ideal solution to combat the negative The intestinal microbiome plays several strain of yeast selected by Alltech (Spring et consequences of diversity reduction crucial roles in the animal, including the al, 2015). Depending on the target species, following antibiotic administration. regulation of cell turnover in the gut wall, their ages and the protocol chosen, Bio- competition for nutrients, the modification Mos® 2 is included in ruminant diets at a When comparing first- and second- of digestion, competitive exclusion of rate from 2 to 20 grams per head per day. generation MOS- and MRF-based products pathogens, the metabolism of mucus Due to its enhanced bioactivity, it can be such as Bio-Mos® and Bio-Mos® 2, it is secretions and modulation of mucosal supplemented at lower levels than those important that the end user understands immunity. It is critical that the microbiome typically seen when using generic MOS that form defines function. Individual MOS- functions to its fullest capability in order to products. and MRF-based products will have widely maintain gut health and maximize growth. differing compositions, and while attempts The effects of Bio-Mos® 2 supplementation have been made to compare products based Mannoproteins and mannanoligosaccharides on health and performance have been on their total mannose content, studies have account for more than 40% of the studied comprehensively, and this second- shown that not only the extent but the type carbohydrate in the cell wall of Saccharomyces generation MRF product has proven of carbohydrate branching in these products cerevisiae and are one of the most widely extremely effective at improving weight gain is the key factor in controlling efficacy. studied functional prebiotics used in and feed conversion efficiencies while also Essentially, not all MOS or MRF products will animal feeds. The application of prebiotic supporting gut integrity and strengthening act in the same manner. Innovative analytical mannan structures present in yeast cells defenses against pathogens. tools developed by Alltech, such as ELMAA fed to animals was first studied by Alltech and ELLA, enable the detection of Bio-Mos® in 1993 with the development of Bio-Mos® More recent studies on Bio-Mos® 2 have 2 in feed and measure its biological activity, (Newman et al 1993). An extremely large set focused on the product’s effects on the allowing for traceability and quality control of studies clearly establishes that the use of overall bacterial community of the gut — not management. first-generation mannose-based (MOS) cell just specific bacteria — and such work has wall fractions, such as Bio-Mos®, in animal shown that supplementation with Bio-Mos® Having spent more than 30 years researching feeding strategies can have beneficial effects 2 can modulate intestinal microflora (also gut health, Alltech is recognized for its on animal health and productivity (Spring et known as the microbiome), enabling it to leadership and expertise in the field of al, 2015). function to its fullest capability (Corrigan and glycomics, with the accumulation of more Murphy, 2016; Corrigan et al, 2018, Franklin than 700 research studies, including over The best-characterized activity of Bio-Mos® et al, 2005; Heinrichs et al, 2003; Quezada 150 peer-reviewed papers, on the effects of is its ability to agglutinate or aggregate et al, 2007). carbohydrate fractions such as Bio-Mos® 2 pathogenic bacterial cells containing Type 1 in animal production systems (Spring et al, fimbriae. In the gastrointestinal tract, lectins Commercial trial work using Bio-Mos® 2 has 2015). (carbohydrate-binding proteins) on bacterial demonstrated that gut function becomes cells bind to complementary carbohydrates normalized following the enhancement of Closing the gap between ideal and actual on animal epithelial cell surfaces. This overall microbial diversity. Reproducible and performance is essential to maximize process is critical to the initiation of consistent alterations in microbiota have profitability. Bio-Mos® 2 is a cost-effective, bacterial colonization and any associated been noted, resulting in enhanced microbial safe, traceable and natural growth permitter. pathogenesis. Bacterial pathogens can diversity. The greater the diversity of the From start to finish, it is a key part of a also attach to Bio-Mos® due to its unique microbes, the healthier the gut, and the use strategic feeding program. References Corrigan, A., Russell, N., Welge, M., Auvil, L., Bushell, C., White, B. A. and Murphy, R. A. (2018) The use of random forests modelling to detect yeast-mannan sensitive bacterial changes in the broiler cecum. Scientific Reports Vol. 8, Article number: 13270 https://rdcu.be/5Q6g Corrigan, A., and Murphy., R. (2016). Effect of dietary mannan-rich fractions on bacterial communities, a new approach with old data. 67th Annual Meeting of the European Federation of Animal Science, Belfast, Ireland. Franklin S., Newman M., Newman K. and Meek K. (2005). Immune parameters of dry cows fed mannan oligosaccharide and subsequent transfer of immunity to calves. Journal of Dairy Science, 88: 766–775. Heinrichs A.J., Jones C.M. and Heinrichs B.S. (2003) Effects of mannan oligosaccharide or antibiotics in neonatal diets on health and growth of dairy calves. Journal of Dairy Science, 86: 4054–4069. Jacques K.A. and Newman K.E. (1994) Effect of oligosaccharide supplements on performance and health of Holstein calves pre- and postweaning. Journal of Animal Science, 72 (Suppl. 1): 295. Newman K.E, Jacques K.A. and Buede R. (1993) Effect of mannanoligosaccharide on performance of calves fed acidified and nonacidified milk replacers. Journal of Animal Science, 71(Suppl. 1): 271. Quezada V.C., Babatunde B.B. and Frankel T.L. (2007) Effect of mannan-oligosaccharides on the mucosal immune system of dairy calves. Journal Animal Science, 85 (Suppl.1): 211. Spring, P., Wenk, C., Connolly, A., & Kiers, A. (2015). A review of 733 published trials on Bio-Mos®, a mannan oligosaccharide, and Actigen®, a second-generation mannose rich fraction, on farm and companion animals. Journal of Applied Animal Nutrition, 3, E8. doi:10.1017/jan.2015.6. 4
Backed by science for them. Healthier calves for you. Bio-Mos® 2 continues the legacy of Bio-Mos® by improving upon Alltech’s trademark technology. Formulated to feed the gastrointestinal tract, Bio-Mos® 2 increases support for gut integrity and colostrum quality to better promote overall performance at all stages of cattle production. Learn more at Alltech.com/Bio-Mos2 Alltech.com AlltechNaturally @Alltech © 2020. Alltech, Inc. All Rights Reserved. US_DA_BioM2_ad1
Normal = healthy, and it starts with what goes in. BOVAMINE® brand probiotic products support normal GI functions in cattle. They can be a natural, safe, sustainable part of your solution. Visit www.chr-hansen.com to find the product best suited to your needs. BOVAMINE® Defend is listed in the BIFSCO pre-harvest library as a product which has met the established requirements for listing.
THE ROLE OF CATTLE MANAGEMENT IN THE BATTLE THE BEEF INDUSTRY FACES AGAINST SALMONELLA writers // Dr. Jennifer Schutz, Allen McDonald, and Jim Turner Salmonella is a challenging pathogen they are challenged with stress factors has been shown to significantly to control as it can affect cattle within such as heat, diet changes, or other reduce the shedding of Salmonella. every stage of production. From immune challenges. Older calves Additionally, a research trial conducted pregnant cows to feedlot cattle, will also have high temperatures and at Texas Tech University found that Salmonella can cause economic severe diarrhea which can contain LA51 reduced the prevalence and issues for producers. In addition to blood, mucus, and shreds of intestinal concentration of Salmonella in lymph the burden of Salmonella to the live lining. Severe dehydration and nodes. The benefit of using LA51 as a animal, it also has major economic depressed feed intakes will also occur. pre-harvest intervention may also have issues on the beef production side Illness will usually last 7-10 days with benefits to the producer as increased as Salmonella is a leading cause of recovery taking between two to three performance, reduced late term foodborne illness. Research has found weeks. One of the major issues with dead’s, and overall health benefits that Salmonella has a unique ability calves infected with Salmonella is that to the cattle are often observed to survive within the gastrointestinal some will become carriers and may and documented within numerous tract and lymph nodes of cattle for shed the pathogen for prolonged research trials.1 long periods of time; because of periods of time. Unfortunately, this, determining how to manage Salmonella is unique in the fact that Conclusion Salmonella is absolutely critical to it can survive and replicate within the It is crucial that the beef industry herd health and food safety concerns. very immune system responsible for continue to find ways to reduce killing it. Salmonella contamination Salmonella prevalence within our beef Detection of Salmonella is challenging to manage as cattle supply. The major challenge facing Based upon NAHMS 2011 feedlot shedding the pathogen pose risk to this goal is keeping Salmonella from data, a very low percentage of all other high-risk calves. entering the immune system. Proper feedlots monitor for Salmonella pen and nutritional management can (6.9%). Researchers have found that Approaches for reduction of help reduce some of these issues. milk production and performance Salmonella Keeping pathogens from breaking can decrease due to Salmonella but Treatment of Salmonella is very through the gastrointestinal tract rarely are there easy to detect signs of challenging and not very successful. and supporting the immune system infection. Management plays a tremendous of these cattle are critical barriers role in the effectiveness of reduction that also need to be managed. One Although Salmonella is usually of this pathogen. Because Salmonella option for producers looking for an undetectable in feedlot cattle, younger is transferred from animal to animal economical way to reduce pathogen calves are very susceptible to death via fecal-oral route, anything that can prevalence while also supporting the from this disease. Colostrum-deprived potentially spread this bacteria must overall health of cattle is BOVAMINE calves are at highest risk of developing be properly cleaned and managed. In DEFEND®. Salmonella reduction severe symptoms such as high fevers addition to key hygiene management will ultimately take producers and (105°-107°F), smelly, watery diarrhea, practices, research has found that packers working together to develop dehydration and death within one to specific probiotics can also help and implement multiple hurdled two days. As calves get older, they are reduce the shedding of Salmonella. approaches for the reduction of this less at risk of death, but can still show Lactobacillus animalis (LA51), the key pathogen from both the pre- and clinical signs of the pathogen when strain within BOVAMINE® products, post-harvest sides. References 1 Reduced Burden of Salmonella entericain Bovine Subiliac Lymph Nodes Associated with Administration of a Direct-fed Microbial Vipham et al. - Zoonoses and Public Health - 2015 7
MAKING HIGH-QUALITY TMR: TIPS TO PROTECT FINISHED FEED writer // Eugene Rodberg / sr. product manager / Kemin Animal Nutrition & Health – North America Total mixed rations (TMR) as microorganisms is fueled by Measuring temperatures of we know them today are an nutrients in the TMR that were the TMR and taking readings invention of primarily the last 50 targeted for the dairy cow. throughout the day is a great years. Prior to TMR, dairy herds way to monitor secondary were fed predominately forages Additionally, a byproduct of fermentation. Producers are often with a limited amount of grain microorganism growth and surprised to learn how quickly the delivered at milking time. Dairy metabolism is heat. Thus, not TMR heats up. In just a few hours, producers started moving toward only do the non-beneficial wild yeast and mold counts grow TMR feeding as milk production microorganisms reduce the exponentially. Feed samples, per cow increased, herds became nutrient density of the TMR, sent to a lab for analysis, may not larger, free-stall and large-group they also render the TMR less represent the extreme situation handling of cows became more desirable to the cow as the ration of a cow’s experience. Your common, and milking parlors temperature increases. best indication of a problem is became more prevalent. The to monitor the TMR temperature earliest known abstract reports What causes the ration to heat? and watch how the cows eat their in the Journal of Dairy Science Well fermented silage resists ration. When the cows back off, on feeding “complete rations” or heating when exposed to fresh feed quality may be the issue. TMR may have appeared in the air (oxygen), a condition called 1950s. The earliest full-length aerobic stability. Silages that The quality of a TMR can article on TMR in the journal was take longer to heat after facing degrade quickly in summer published in 1966. are considered more aerobically conditions. Preventing stable than silages that heat secondary fermentation and its Challenges quickly. In addition to aerobic accompanying heat spike is so The challenge associated with stability, blending different feed important and is especially true feeding cows these nutritionally ingredients in a TMR allows if the forage or feed quality is complete diets is we are also microbes access to additional already marginal. feeding a complete diet to nutrients along with air. This beneficial and non-beneficial process, along with a hot feed Key feed management microorganisms. When non- bunk and higher humidity, creates practices to keep feed fresh: beneficial wild yeast, mold and the perfect growing conditions for • Feed twice per day. If possible, bacteria grow in the TMR, thermal molds and wild yeast to rapidly provide fresh feed when and aromatic related off-feed grow. The fermentation of the conditions are relatively cool. events, milk fat depression and feed generates heat and in Consider offering two-thirds of other digestive upsets are likely return, increases the temperature the TMR in the late afternoon/ to occur. of the TMR. It’s also possible a early evening and one-third in dairy is adding more moisture to the morning. Summer temperatures and the ration by adding green chop • Push-up feed frequently. humidity increase the challenges forages or seasonal wet by- • Carefully manage the face of posed by the growth of mold and products which are not ensiled. an upright silo, bag or bunker. bacteria in the TMR. Summer The moisture content of the TMR Removing 12 inches a day is heat and humidity dramatically may also increase as water from recommended, and it is best to increase the growth of these cow cooling sprinklers drifts onto remove from the entire face. non-beneficial microorganisms. the feed. • Use preservative products such Of course, the growth of these 8
as bacterial inoculants and a molds or wild yeast. For example, silage was stable for 35.3 hours blend of organic acids at the propionic acid will control some before heating. Silage treated time of harvest. molds species but is ineffective with a blend of organic acids was • Always use a thermometer to on other strains. At the same time, stable for 49.3 hours. In addition, check temperatures. Feeling propionic acid has limited efficacy the application of organic acids the temperature of the feed on wild yeast. A mold inhibitor reduced the peak temperature of with your hand will not give you with a higher total acid content the corn silage when exposed to accurate results. containing acetic, benzoic and/ air. • Use highly concentrated, or sorbic acids has demonstrated buffered, broad-spectrum mold efficacy in controlling yeast Summary inhibitors. Buffering the blended growth. Multiple acid formulations Weather is unpredictable. When organic acids makes them less are highly effective at controlling labor is limited, feed quality is corrosive and much safer to yeast. not optimal, and when conditions handle. dictate, incorporating a premium Research conducted at the mold inhibitor into the TMR can Research and solutions University of Delaware evaluated help to protect your investment. If wild yeast is a problem, adding the use of a buffered blend of an organic acid blend with organic acids (propionic acid, For more research or product propionic acid and other acids potassium sorbate, and sodium information, please visit to mixed feed will be highly benzoate; 87% active ingredients) kemin.com/feedquality or email effective at controlling secondary to reduce TMR heating and keminag@kemin.com. fermentation and heating of the improve aerobic stability of TMR. Single acid treatments often corn silage. When silage was References available upon fail to control a wide variety of exposed to air, untreated corn request KEMIN IS THE SCIENCE BEHIND HEALTHIER CATTLE Since 1961, Kemin has utilized molecular science to develop industry-leading solutions for gut health, ruminant nutrition and feed quality. It’s just one of the ways we sustainably transform the quality of life every day for 80% of the world with our products and services. kemin.com/cattle #TheScienceBehind 9 © Kemin Industries, Inc. and its group of companies 2020. All rights reserved. ® ™ Trademarks of Kemin Industries, Inc., U.S.A.
Bring BROADBAND TO YOUR Community online learning telemedicine community service Rural students often lack Rural Americans lack access Join the the growing coalition access to broadband Internet. to healthcare. About 20% to help close America’s digital Only 55% of people living in of Americans live in rural divide by participating in the rural areas have access to areas without easy access American Connection Project Internet speeds that qualify to primary care or specialist Broadband Coalition. as broadband, compared to medical services. Only about 94% of the urban population one in 10 physicians practice in Currently more than 150 that qualify as broadband. rural areas in the U.S. communities across the nation have joined in the Provide an opportunity for As telemedicine services cause to help connect their broadband access to support continue to rise, residents neighbors to the digital world. your local students achieve need access to online medical success. services. Find out more information on how to help close the digital divide. Please contact your Nutra Blend sales representative today!
[ ADVERTISEMENT ] Knowledge Is Power Unraveling the complexities of liver abscess disease can help us optimize its management. A full understanding of the liver abscess disease complex is elusive, as is determining when and how to best at the feedyard that may affect outcomes and quantify trim losses and carcass characteristics associated with liver have a higher prevalence of liver abscesses compared to others, such as Holsteins. One possible explanation is that Holsteins manage it. “Knowledge is key. If we abscesses. In total, 161,491 livers were spend more days on feed than beef cattle don’t know how and why abscesses are evaluated from seven fed-beef processors (roughly 350 days vs. approximately 200 formed, we won’t know how to best control in the Central Plains, Desert Southwest, days). More research needs to be done to them,” says Scott Laudert, Ph.D., SBL Tech High Plains, Northeast, Northern Plains determine why these cattle appear to be Consulting. In addition to understanding and Pacific Northwest. more susceptible. current management strategies, research The average liver abscess incidence for “This disease is multifactorial,” Laudert efforts must continue to discover new cattle harvested at fed-beef processing agrees. “In addition to feedlot region, cattle ways to make liver abscess management plants was 21.3%. Incidence was lowest in type, time of year, the diet composition and more effective. Casey Maxwell, Ph.D., the Northeast (10.0%) and highest in the when and how it’s fed to the cattle can all operations analyst at Cactus Feeders, Pacific Northwest (33.8%) (Figure 1). combine to affect incidence. Because there adds, “Given the increasing pressure for are no outward signs of the disease, there’s accountability when using antibiotics Figure 1. no way to pinpoint which factor is most in cattle, understanding more about the Average Fed Cattle Liver Abscess Prevalence important. This isn’t a straightforward disease can help us optimize how and when 40 disease, so there are no easy fixes.” to use them.” 33.8 Percent Abscesses 30 25.5 24.3 “Given the increasing pressure for accountability “Because there are no outward signs of the 20 18.5 when using antibiotics in cattle, understanding Desert Southwest Pacific Northwest 15.5 Northern Plains disease, there’s no way to pinpoint which factor Central Plains 10.0 more about the disease can help us optimize High Plains 10 is most important. This isn’t a straightforward Northeast how and when to use them.” disease, so there are no easy fixes.” 0 — Casey Maxwell, Ph.D., Cactus Feeders — Scott Laudert, Ph.D., SBL Tech Consulting When evaluated by cattle type, fed “Currently, Tylan® (tylosin) is the most A huge price to pay Holsteins had a higher abscess incidence efficacious tool available for reducing Liver abscesses continue to be a costly rate (25.0%) than fed beef steers (18.2%) or the incidence of liver abscesses in cattle,” problem for the industry through the loss fed beef heifers (19.1%). says Maxwell. Elanco remains committed of condemned liver and other viscera Complex, variable and puzzling to learning more about the liver abscess because of reduced animal performance, “The liver abscess disease complex has disease complex, developing strategies lower carcass yields and decreased so much variability,” says Maxwell. “For that help ensure judicious antibiotic use processor efficiency. Using conservative example, we can see drastically different and searching for new solutions. estimates, viscera losses are approximately incidence levels from one pen of cattle to $60 million per year.1 Visit elanco.us or contact your Elanco another that have come from the same sales representative to learn more Surveying for liver abscess incidence1 location and that have been managed the about Tylan. Liver abscess prevalence trials were same way.” Another unanswered question conducted to help determine conditions is why certain breeds and types of cattle The label contains complete use information, including cautions and warnings. Always read, understand and follow the label and use directions. Tylan® (tylosin) CAUTION: Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian. For reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes: Feed continuously as the sole ration at 8 to 10 g/ton of tylosin (90% DM basis) to provide 60 to 90 mg/hd/d. Elanco supports the use of shared-class antibiotics for therapeutic uses while under the oversight of a veterinarian. Visit https://www.elanco.com/healthy-purpose#responsible-use-of-antibiotics for more details on Elanco’s Antibiotic, Welfare and Sustainability Policies. 1 Ryan Travis Herrick dissertation, West Texas A&M University. 2018. Tylan, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates. © 2020 Elanco. PM-US-20-0339
[ ADVERTISEMENT ] Smart Strategy Makes a Difference Strategic use of Tylan® (tylosin) can effectively control liver abscesses. D espite the ongoing commit- ment of the industry to learn more about the liver abscess Timing of treatment Elanco’s research indicates that the longer Tylan is fed to cattle and Being strategic With limited alternative options to this impactful disease, Tylan remains disease complex and how to best the earlier Tylan is provided in a cost-effective tool with a proven manage it, the incidence of this the feeding period, the better liver return on investment. Elanco’s costly multifactorial condition is abscesses are controlled. A recent research indicates that the earlier not decreasing.1 study has shown that the voluntary Tylan is provided in the feeding removal of Tylan prior to slaughter period and the longer it is fed to may not impact its effectiveness in cattle, the better liver abscesses are With limited alternative options reducing liver abscess incidence at controlled. Continued research is to this impactful disease, Tylan slaughter (Table 1).1 needed to better understand and remains a cost-effective tool with address this costly disease complex. a proven return on investment. TABLE 1. A heavy cost to the bottom line This multifactorial disease Effect of Strategic Use of Tylan significantly affects the beef indus- on A+ Abscess Incidence try through the loss of condemned livers and other viscera because 9 of reduced animal performance 8 8.49 and carcass yield, and decreased Percent Abscesses packer processing efficiency. Using 7 7.36 conservative estimates, viscera 6 losses are approximated at $60 million per year.1 5 5.67 4.75 4.96 The effect of varying the Tylan 4 4.44 feeding schedule 3 First 126 Days First 42 Days First 84 Days Last 84 Days A study was conducted to determine the effect of feeding duration and 2 No Days All Days timing on the efficacy of Tylan at 1 reducing liver abscesses.1 Crossbred steers (3,360 head) in the Texas 0 Panhandle were divided into six Tylan Treatment Group treatment groups fed the same ration for 164 days (February to August 2017). The average initial weight was 830 lbs, and final weights ranged from 1,451 to 1,461 lbs. Visit elanco.us or contact your Elanco sales representative to learn more about Tylan. The label contains complete use information, including cautions and warnings. Always read, understand and follow the label and use directions. Tylan® (tylosin) CAUTION: Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian. For reduction of incidence of liver abscesses associated with Fusobacterium necrophorum and Arcanobacterium pyogenes: Feed continuously as the sole ration at 8 to 10 g/ton of tylosin (90% DM basis) to provide 60 to 90 mg/hd/d. Elanco supports the use of shared-class antibiotics for therapeutic uses while under the oversight of a veterinarian. Visit https://www.elanco.com/ healthy-purpose#responsible-use-of-antibiotics for more details on Elanco’s Antibiotic, Welfare and Sustainability Policies. 1 Elanco Animal Health. Data on file in conjunction with the Ryan Travis Herrick dissertation. Tylan, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates. © 2020 Elanco. PM-US-20-0595
CONTROLLING PATHOGENS ON DAIRIES WITH A WHOLE FARM APPROACH writer//Tom Rehberger, Ph.D. / Director, Research and Product Development / Arm & Hammer Animal and Food Production Harmful pathogens lurk everywhere on a dairy, leading pneumonia. These illnesses compromise immunity and to a cycle of infection and reinfection that hampers herd take energy away from growth needs, leaving calves health and performance. Taking a whole-farm approach more susceptible to other illnesses. Infected calves can to pathogen reduction can help you break this cycle and also shed pathogens into the manure to heighten risk of maintain your herd’s productivity. reinfection. Controlling pathogens on your dairy starts by In the lactating herd, C. perfringens Type A is often understanding the pathogen cycle. Pathogenic organisms implicated in hemorrhagic bowel syndrome (HBS). proliferate inside animals’ digestive systems and enter Subclinical levels can cause cows to go off feed and the environment through manure. These organisms often reduce their milk production, even without signs of survive in the manure pit or lagoon, with the potential clinical disease. to contaminate growing plants when manure is spread on fields. When animals eventually consume the crop in Left uncontrolled, the pathogen cycle continues through the form of grazed or harvested forage, the pathogens cows’ manure, which often contains clostridial bacteria, return to their digestive systems and the cycle begins including both toxigenic and non-toxigenic C. perfringens anew, with damaging effects on health and productivity. strains. Other clostridial strains can impact feed intake, rumen efficiency and gastrointestinal function. Pathogen prevalence Three of the most prevalent pathogens on dairy farms are Break the pathogen cycle Clostridia, Salmonella and pathogenic E. coli. Realize that To limit animals’ exposure to these and other pathogens, your operation may be different from your neighbor’s, your goal should be to decrease the overall pathogen with different organisms present in the environment. load on your dairy by breaking the pathogen cycle. Assessing the existing pathogens can help identify a solution for each area of your operation. One solution is feeding CERTILLUS™ to target specific pathogenic challenges, control them and reduce Since 2015, researchers at Arm & Hammer Animal and reduce their levels in an animal. The Targeted Microbial Food Production have analyzed clostridial risk on U.S. Solutions™ in CERTILLUS use proprietary strains of dairy operations. Among their findings1: Bacillus to help make calves and cows more resilient • Over half of the 20,510 fecal samples tested from 509 against C. perfringens while reducing pathogen shedding dairies in 30 states fell into a high-risk category based into the manure. ARM & HAMMER™ researchers select on levels of clostridial bacteria the best Bacillus strains to combat the specific challenges • More than 70 percent of 1,200 calf fecal samples tested in your herd by analyzing the Microbial Terroir™—which positive for pathogenic C. perfringens, with the highest includes the environment, soil and animals at your prevalence in calves under three weeks old specific location. • Forage samples from 457 herds revealed Clostridia presence in 83 percent of haylage and 57 percent of Conclusion corn silage Although it is not possible nor desirable to create a totally pathogen-free environment, proper management Pathogen vulnerabilities in all areas of the operation can help you reduce Young calves are particularly vulnerable to environmental risk of transmitting disease-causing organisms. Visit pathogens. Exposure to pathogens during the first hours AHfoodchain.com to learn more on the benefits of and days of life can lead to clinical scours followed by feeding CERTILLUS to dairy animals. Notes 1 Data collected and analyzed by ARM & HAMMER. 13
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ZINPRO PERFORMANCE MINERALS® REDUCE PRODUCTION COSTS AND INCREASE SOW LIVABILITY writer //Zinpro Corporation Minor changes can have major scenarios. combination of lowering input costs impacts when feeding Availa®Sow and increasing output. By lowering throughout gilt development, Have you considered the cost of inflammation, Zinpro Performance gestation and lactation. Sow sow mortality in your system and its Minerals re-direct more nutrients mortality continues to be a challenge impact on the cost of production? towards a productive outcome, and in the U.S. market with systems What value could your system see if on the sow farm the KPI that matters commonly experiencing greater you were able to lower sow mortality, is cost per weaned pig. than 10% sow mortality on average and ultimately replacement rate by (www.piglivability.org). Addressing 1 or 2%? Would you be willing to By improving a sow’s ability to sow mortality and the root causes invest in strategies to help achieve cope with immune pressure, more of sow mortality to lower sow farm this through nutrition, so your health nutrients are available for the last replacement rate simultaneously and management strategies had physiological priority, reproduction. addresses cost of production; by greater impact? A recent meta-analysis of Zinpro lowering your replacement rate sow data revealed a 0.32 pigs per you lower your cost of production. Zinpro Performance Minerals® have litter increase in born alive. While an Cost per weaned pig is one of the demonstrated not only to lower increase in total born alive doesn’t’ three variables that explain 98% of systemic inflammation in sows, but guarantee and increase in pigs per the variation system profitability. also mitigate system mortality which sow per year (PSY), adding effective Effective trace mineral nutrition using is ultimately what impacts cost of trace mineral nutrition to your sow Zinpro Performance Minerals is a tool production. In recently completed program is a means to improve that can help you achieve a lower field work, inclusion of Zinpro Availa- management opportunity to cost per weaned pig by lowering Sow, part of the Nutra Blend Availa- increase PSY and further lower cost input costs through reduced sow Sow TM Plus sow premix, resulted per weaned pig. mortality and increasing output with in mitigation of sow mortality on a increased born alive. system level (Figure 1). The inclusion of Availa-Sow in the sow’s diet provides zinc, Inflammation impacts Figure 1 manganese and copper from nutrient utilization, performance trace minerals. physiological priority By making a minor change to and system profitability. the sow’s diet and including More than 50% of sow Zinpro Performance Minerals® mortality is attributed from Availa-Sow or the Nutra to “unknown” reasons Blend Availa-SowTM Plus sow (www.piglivability.org), premix, a major impact can be and while it’s real that achieved on cost per weaned we don’t know why many pig directly linked to sow sows die, it’s reasonable performance. that inflammation is at the core of the problem. Inflammation is necessary for positive health outcomes. It alerts the immune system to challenges; when To learn left uncontrolled it can rob animals of Past research has indicated that m o r e necessary fuel for production and, in Zinpro technologies improve the about extreme conditions, result in natural robustness of the feet and the gut, including death or euthanasia, impacting ultimately leading to optimal health Availa- system profitability. Persistent outcomes and survivability.1,2 By Sow in immune responses divert nutrients lowering sow mortality, reductions in your swine feeding and nutrition away from measurable KPIs and replacement rate can be recognized program, contact your Nutra Blend ultimately impact system profitability leading to a lower cost per weaned account manager or a Zinpro Swine in the form of involuntary culls, pig as a result of fewer gilt entries. account manager today. re- treats or other profit robbing Reducing cost of production is a References 1 Leite, F.L. et al., 2018 2 Anil, S.S et al., 2010 15
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MANAGEMENT TIP TOPIC: BUILD A HEALTHY RUMEN ENVIRONMENT writer //Diamond V The health of your herd starts the mix is critical. The end goal is to as well as the cow. Remember - with good rumen management. meet the required nutrient profile. when we think about the microbial Healthy cows perform better, and community and the contribution to better performance can lead to Encourage the Growth of Beneficial the cow, it is about the protein and greater production and ultimately Rumen Microbes: energy supplies. Anything we do that greater profitability. Without a well- A nutritionally balanced diet disrupts the balance of the numerous functioning rumen, your herd could be is important as it provides an rumen microbial populations can more susceptible to a variety of health environment that maximizes growth influence how well the cow is able to complications and costly expenses. and activity of the rumen microbial utilize the nutrients that we are putting Two things are vital when it comes to community. Through fermentation of in front of her. optimal rumen health: a stable, active, different ration components inside the and healthy microbial population; rumen, microbes work to break down One way to give the rumen microbes and maintaining a suitable rumen what a cow eats, producing volatile what they need to grow is incorporating pH level.. Without these two things fatty acids (VFA) which the cow utilizes appropriate feed additives in the in place, the rumen becomes less for its energy needs. Also, rumen cow’s diet. NutriTek® is Diamond V’s efficient at digesting feed. microbes utilize non-protein nitrogen most advanced natural* nutritional (NPN) to synthesize microbial protein, health product for all dairy animals. Incorporate the three management which becomes available to the Diamond V has been in the animal tips listed below to build a healthy cow. It’s all about providing the right feed additives business for more than rumen environment. nutrients to the right populations to 75 years. Our natural* products are produce the most beneficial levels of made from a proprietary fermentation Create the Right Balance in the volatile fatty acids (VFAs) The three process that helps optimize animal Ration: main VFAs are: health, animal performance, immune A healthy rumen starts with a well- • Acetate: This is the end product of support, and food safety worldwide. balanced ration. The right balance fiber fermentation. It’s necessary NutriTek can help support better gut of nutrients ensures micro-organisms for milk fat, so too little acetate health, facilitate balanced immune work effectively, and the cow can production creates a lower fat test. function, and ultimately aid in obtain the greatest nutritional benefit • Propionate: This is the result of increased production and profitability. from the feed. A consistent and fermentation of starch and sugars. A cow with a healthy rumen is able to constant supply of nutrients is key for This provides the cow with energy for digest feed more efficiently and make optimal rumen pH and rumen microbe weight gain and lactose production more energy and nutrients available growth and activity. inside the udder. If propionate for milk production and other bodily levels are reduced, as they can be functions. The bioactives in NutriTek However, it’s all a balancing act with the in high-fiber diets, milk production work synergistically to help balance end goal of having each mouthful of can suffer. immunity and optimize digestive feed be as close to complete nutrient • Butyrate: This is metabolized in the health by promoting a healthy rumen profile for the cow. When building a liver into ketone bodies, which are microbiome and delivering beneficial diet, focus on the nutrients critical used as a source of energy for fatty antioxidant effects. Creating the right to a cow’s daily needs like vitamins, acid synthesis and the development balance in the ration, establishing minerals, carbohydrates (starch, fiber), of other body tissues. beneficial VFA production, and fats, protein, and water. It is important feeding a product that favorably to understand how these components Feed Products That Give Rumen impacts the rumen microbes can interact and their influence is, to rumen Microbes What They Need to Grow: ultimately improve gut health and microbial function. The other thing to Formulating the precise nutrient immune strength. The result will be keep in mind is feed sorting. Cows will requirements in the diet can be a increased feed intake, improved sort feed based on preference and challenge. We must build a diet that efficiency, and more milk production. particle size; therefore, uniformity in feeds both the microbial community 17
BALCHEM RESEARCH SUMMARY: STUDY MEASURES METHYL DONOR CONTENT OF KEY COMMODITIES writers // Kari Estes1, Barbara Barton1, Ryan N. Dilger2, and Thomas Powell1 1 Balchem Corp., New Hampton, New York, United States 2 Department of Animal Sciences, University of Illinois, Urbana, Illinois, United States. Purpose Conclusions The goal of this project was to sample and analyze Accurately characterizing the choline content in numerous soybean meal (SBM) and corn samples commodities has important implications. Using the collected in 2018 for choline and other methyl- Poultry NRC (1994) values to formulate for choline containing compound concentrations to build an could cause a gross under-supplementation in most updated library. diets. Table 2 compares the supplementation rates needed to meet dietary choline requirements when Methods NRC book values and analyzed values are used to Twenty-nine SBM samples and 22 corn samples were formulate a typical (corn/soy based) broiler starter collected from two international countries and 10 diet. states within the United States. Samples were then analyzed at Eurofins Scientific (Des Moines, Iowa) for This discrepancy, coupled with a potentially greater amino acids, choline, betaine, folic acid, and vitamin choline requirement to meet the needs of today’s B12 concentrations. genetically superior production animals, could seriously compromise productivity and producer profitability. Results • In general, corn exhibited lower analyzed methyl- containing nutrient concentrations and was more variable when compared with SBM (Table 1). • Vitamin B12 concentrations in both SBM and corn were low and below detection limits (
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DON’T LET MYCOTOXINS TANK THE PROFITABILITY OF YOUR DAIRY FARM writer // Dr. Rafael Caputo Oliveira Mycotoxins are toxic compounds produced by molds brewer yeast selected among other strains by that, if not well managed, can silently reduce a researchers at Ghent University in Belgium to have dairy farms profitability by reducing feed intake and the highest immunomodulation activity. Our most milk production, increasing diseases, and reducing advanced formula also contains antioxidants and reproductive performance. In a mycotoxin survey botanicals that help alleviate and repair the cellular with feed samples from farms throughout the United damage caused by mycotoxins in dairy cows. States in 2019 (Borutova, 2019), 4.5 to 50% of all corn and silages were contaminated with zearalenone and Is Adisseo MMS efficacy scientifically proven? fumonisin, and 86.4 to 100% of all feed samples were Researchers at the University of New Hampshire contaminated with DON. carried out an experiment to study the capacity of Adisseo MMS on ameliorating the negative effects Screening and, if necessary, eliminating feedstuffs of mycotoxin-contaminated distiller grains in dairy are key to have low dietary levels of mycotoxin. In cows (Whitehouse., et al 2020). The experiment was partnership with global players, Adisseo offers a composed by three dietary treatments: certified, user-friendly, and rapid test for specific 1. Healthy diet mycotoxins. For a complete screening of mycotoxins, 2. Diet containing mycotoxin-contaminated distiller Adisseo also offers through third-party labs wet grains chemistry mycotoxin analysis using LC/MS-MS. 3. Diet containing mycotoxin-contaminated distiller grains and Adisseo MMS. Eliminating contaminated feedstuffs is the best solution, but in some circumstances due to inventory The distiller grains used in this experiment were issues this recommendation is not practical. In those naturally contaminated with high levels of the cases, once the feedstuff is contaminated with most prevalent mycotoxins in the United States mycotoxins, the most feasible solution is the use of (zearalenone, fumonisin B1, and DON). dietary additives to prevent and mitigate the impact of mycotoxins and improve dairy profitability. As expected, cows fed the diet containing contaminated distiller grains had reduced dry matter Once you are equipped with a mycotoxin screening intake and energy corrected milk in 4.4 and 2.9 lbs/ analysis from single ingredients or TMR, we day, respectively, and had impaired immune function. recommend using the app MycoMan® that can be downloaded for free from the Apple Store (iOS) and Cows fed the diet containing contaminated distiller the Google Play Store (Android). This app helps you grains and Adisseo MMS had a less severe negative to diagnose a potential mycotoxin problem and impact on dry matter intake (-2.6 lbs/day) and define the best strategy to prevent or control possible interestingly, immune function was similar to cows diminished dairy performance by suggesting the type consuming the healthy diet. of products and their doses. It is also worth noting the Adisseo MMS-fed cows Preventing dairy cows from mycotoxin poisoning started the trial with the lowest energy corrected milk does not need to be expensive; Adisseo offers two production but by the end of it, they had the highest mycotoxins management solutions (MMS) that can production. cost as low as 2 cents daily per cow. Our products prevent and control a wide range of mycotoxins As a conclusion, these results prove the efficacy harmful effects through detoxifying and repairing of Adisseo MMS in protecting dairy cows from the modes of action. All Adisseo MMS contain a high- harmful effects of the most prevalent mycotoxins in quality bentonite (97% affinity to aflatoxin; Trilogy the United States Analytical Lab. certificate) and a high-quality dried Sources Borutova, R. 2019. Adisseo: United States of America 2019 Mycotoxin Survey in Corn and Corn Silage. Whitehouse, N. L., H. C. Robertson, B. K. Kerns, S. M. Hollister, L. H. P. Silva, and S. M. Fredin. 2020. Effects of supplemental mycotoxin deactivator on lactation performance of Holstein cows fed natural mixed mycotoxin contaminated feed. J. Dairy Sci. 103 (Suppl. 1):125. (Abstr.) 20
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