PHD VIRTUAL OPEN WEEK 2021 - PHD COURSE IN BIOENGINEERING AND MEDICAL-SURGICAL SCIENCES SUPRADISCIPLINARY TRAINING IN ADVANCED TECHNOLOGIES FOR ...
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PHD VIRTUAL OPEN WEEK 2021
POLITECNICO DI TORINO PhD course in Bioengineering and Medical-
Surgical Sciences
Supradisciplinary Training in Advanced Technologies for New
Therapeutic Approaches
Description
• The joint programme between Politecnico di Torino
and Università degli Studi di Torino started six years ago (30
cycle);
• It was established to provide a common, high-level training for
engineers, biologists, physicians, surgeons and dentists as new
players in an interdisciplinary and intersectorial environment focused
on an improved managing of human health. IMAGE
• The doctorate is an effective incubator from which innovative
solutions that could have a deep impact on reality of healthcare and
production system will originate through an interdisciplinary
collaboration at the research and training level.
• In the future this training will have a new home in the Turin Health,
Innovation and Research Park.
Description
General Training Objectives:
• offer capable and motivated students a qualified training in
Bioengineering and Medical-Surgical Sciences and in the
interdisciplinary areas connected to them;
• integrate a solid theoretical-conceptual preparation with full
mastery of the most up-to-date quantitative and qualitative IMAGE
research methodologies and techniques (hands-on training);
• combining the specialization of the disciplinary field and the
plurality of theoretical and methodological approaches, in order
to provide doctoral students with an easily expendable
training.
Topics
Surgery
Odontostomatology
Anesthesiology-Intensive Care
Advanced Therapies
Imaging Diagnostics Regenerative Medicine
Mechanical Bioengineering Nanomedicine
Robotic Surgery
Biomaterials and Bionanotechnology
Electronic Bioengineering
Surgery
Topic Description
- Robotics & Automation, Artificial Intelligence applied to surgical
disciplines.
- 3D reconstruction and modelling for surgical planning.
- Bioengineered prosthesis development for surgical application.
I choose it if I am interested in:
• Improving technology applied to any surgical discipline in the
fields of robotics, AI, 3D modelling, biomaterials, training &
education.
Job outlet:
• Surgeons of any discipline both academic and not.
• Consultant for companies developing technology for surgery.
• Start-upper.
Odontostomatology
Topic Description
ADVANCED THERAPY IN DENTISTRY AND ORAL SURGERY
I choose it if I am interested in:
• digital work flow for rehabilitating dental and maxillofacial
IMAGE
patients;
And
• personalised dentistry and medicine;
Subtopics
• bone and mineralised tissue engineering.
Job outlet:
• academic tenure track;
• higher specialised professional activities;
• R&D in biomedical companies.
Other Topics
ADVANCED medical technologies are also applied to:
Anesthesiology-Intensive Care
Imaging Diagnostics
I choose it if I am interested in: IMAGE
Improving technology applied to Intensive Care And
Improving technology applied to Imaging Diagnostics Subtopics
Job outlet:
• Anesthesist and radiologist physicians.
• Consultant for companies developing technology for surgery.
• Start-upper.
Biological structures mechanics
Mechanical Bioengineering
Topic Description
Solid & Fluid Biomechanics Group activities are based on computational and
experimental methodologies applied to medicine and healthcare. Fields of Cardiovascular biofluid mechanics
application include biological tissues/districts/organs mechanical characterization
and engineering, research on diseases progressions from macro to nano scales,
devices design and testing.
More specific research areas include: biological materials and structures
mechanics; engineering in surgery; cardiovascular biofluid mechanics;
bioreactors for tissue engineering, regenerative medicine and transport Multiscale and multiphysics modelling
phenomena; multiscale and multiphysics modelling.
I choose it if I am interested in:
• Experimental testing for materials or devices characterization
• Design of devices/experimental set-ups for custom tests
Bioreactors & transport phenomena
• Computational approaches to investigate human districts/organs/tissues
behaviour as well as disease effects and progression or pathological conditions
Job outlet:
• Research centres & laboratories
• Research & development sections of medical companies
• Academic career
Biomaterials and Bionanotechnology
Topic Description
The “Biomaterial and Bionanotechnology” topic aims to develop
enabling technologies for clinical challenges with high social burden
and for unsolved clinical challenges.
I choose it if I am interested in:
• Design of biomaterial, biosurface and smart interface for medical devices;
• Design of integrated diagnosis system (e.g. lab-on chip);
• Advance therapies development.
• Design of biomimetic and smart platforms for clinical needs
Job outlet:
• Implantable medical device companies;
• Diagnosis systems companies; • Advanced Therapies
• Pharmaceutical companies;
• Regenerative Medicine
• Biotech spin-off and start up;
• Research fields in public and private research centers. • Nanomedicine
• Intelligent systems for physiological
Electronic Bioengineering and pathological systems assessment
Topic Description • Radiomics
This topic addresses the development of innovative devices and applications for • Telemedicine
diagnosis, therapy and patient monitoring. Activities range from the design of
instrumentation to biosignals and medical images processing and interpretation. • Assessment of neuromuscular system
and cortico-muscular coupling
I choose it if I am interested in:
• Movement analysis
• Design of innovative devices
• Radiomics and medical imaging
• Intelligent systems for diagnosis, therapy and patient
monitoring
• Telemedicine
Job outlet:
• Research centres & laboratories
• Biomedical companies and healthcare facilities
• Academic careerInternational Dimension
Selected Collaborating Universities
1. HOSPITAL OF THE RUHR-UNIVERSITY BOCHUM (Dott. Jochen Salber – Germany)
«Development of 3D engineered models of bone tissue for the in vitro characterisation of prosthesis coatings» - H2020 EVPRO project (Extracellular
Vesicles Promoted Regenerative Osseointegration)
2. UNIVERSITY OF GENT (Prof. Patrick Segers – Belgium)
« Automatic measurement of pulse wave velocity or arteries» H2020-ICT-2018-2020 InSiDe project
3. MASSACHUSSETS INSTITUTE OF TECHNOLOGY (MIT) (Prof. Roger D. Kamm - USA)
«Fabrication of microfluidic models of tissues and drug release particles» BIOMODE project “Joint research projects with top universities” - Compagnia di San
Paolo (2017-2021)
4. UNIVERSITY OF BASEL (prof. Anna Marsano – Switzerland)
«Laboratory experimentation of dynamic culture devices for Cardiac Tissue Engineering applications developed at Politecnico di Torino laboratories»
5. MAASTRICHT UNIVERSITY (Netherlands)
H2020 Project "Active aGeIng and Osteoporosis: The next challenge for smarT nanobiOmaterials and 3D technologies- GIOTTO GA 8114410"National and International Dimension
International Projects of Excellence
• ERC-CoG-2017 – BIORECAR. Partners: Humanitas Research and Clinical Center, INRIM, University of Naples
Federico II
• ERC-CoG-2015 –Boost. Partners: Università di Pisa, Istituto Ortopedico Rizzoli, Università Politecnica delle
Marche
• Dipartimenti di Eccellenza 2018-22: project supported by MIUR.
• INFRA-P «Sostegno a progetti per la realizzazione e l'ampliamento di IR pubbliche» (iDeaL). Partners: University
of Turin, Dental School, INRIM
• EU H2020 Marie Sklodowska Curie-AMITIE:. Partners: Imperial College London, Université Limoges, INSA Lyon,
Polytechnical University Haut-de-France, University of Erlangen Nuremberg, Federal Institute for Materials
Research and Testing Berlin, Universitat Politècnica de Catalunya, Belgian Ceramic Research Center, St. Gobain,
3D Ceram, Moraker, Anthogyr, Bosch, Starck CeramicsExcellence research project
THE ERC BOOST PROJECT
G.A. 681798
P.I. Prof. Chiara Vitale Brovarone
To RE-CREATE, with a SMART SCAFFOLD,
the physiological microenvironment, in order to
RE-BALANCE the coupling of Oc and Ob and
eventually the coordination of bone resorption
and formation.Excellence research project
THE ERC BIORECAR PROJECT
G.A. 772168
P.I. Prof. Valeria Chiono
To DIRECTLY REPROGRAM cardiac
fibroblasts in the post-infarct cardiac scar
into cardiomyocytes by the in situ release
of microRNAs-loaded NANOPARTICLES
through an INJECTABLE BIOMIMETIC
HYDROGEL, for myocardial
REGENERATION.International Dimension
For the XXXVI cycle (last one):
• 1 grant with funds from the Compagnia di San Paolo to encourage internationalization for foreign candidates
on the topic of smart drug release polymeric hydrogels (Tzanko Tzanov, UPC Barcelona). The foreign university
is also a member of the European University Alliance UNITE! With the Politecnico di Torino;
• at least 2 grants co-financed under the ERC Consolidator - BIORECAR funding. The grant winners will
spend a 6-month period at Duke University School of Medicine, a center that pioneered the direct
reprogramming of cardiac fibroblasts via microRNA, and at Columbia University, a world-leading center in the
engineering of in vitro cardiac tissue models, respectively;
• thanks to the MIUR funding, 4 scholarships were reserved for foreign citizens or Italians permanently
resident abroad who have obtained their degree outside Italy (with an Italian or foreign qualification) and have
demonstrated, thanks to the excellence of their international curriculum, to be able to successfully complete their
studies in Italy benefiting from a substantial bilingualism;
• 1 CO-TUTORING grant with University of Jyvaskyla - Finland.Intersectorial and Interdisciplinary dimension
• This PhD course is intrinsically interdisciplinary as it provides third level training on issues of intersection
between engineering and science medical-surgical and life;
• The Ph.D supervision is characterized by experts of different disciplines of medicine and engineering fields;
• The course belongs to the Ph.D school of both Politecnico di Torino and Università degli Studi di Torino; both Ph.D
schools offer soft skills courses that allow interaction among Ph.D students of different disciplines on transversal
common issues;
• The PhD program offers hands-on training in technologies identified by Industry 4.0 with particular, but not
exclusive, reference to additive manufacturing (AM) and the big data;
• This Ph.D course represents an ideal training environment, in a strong context interaction between the world of
scientific and technological research and that of the clinic.
• In particular AM will be declined in his applications with greater knowledge-based content (microfabrication of
medical devices for use in advanced therapies, diagnostics). The new interdepartmental laboratory
PolitoBIOMed Lab, which also financed 5 PhD scholarships, is hosting research activities additive manufacturing
training.Class Training 60 hr Hard Skills/40 ore soft skills
BIOENGINEERING AND MEDICAL-SURGICAL SCIENCES
Biofluid mechanics & bioimage processing to support cardiovascular surgery strategies, 20h
diagnostics and decision making
Data mining for the analysis of clinical studies 20h
Engineering of surgically inspired medical devices 20h
Planning, management and analysis of chimical and laboratory research 15h
2022
Additive Manufacturing in Bioengineering and Surgery 20h
Advanced Therapies (Nanomedicine, Gene and Cell Therapy) in Surgery 20h
Biomedical instrumentation for physiological monitoring in surgical applications 20h
Robotic principles, materials and applications in biomedicine 15h
Segmentation, recognition and reconstruction of medical images in surgical and pre-surgical applications 20hLab resources
PolitoBIOMed Lab.
Integrative Biomechanics; DISAT GLANCE.
New Materials and Biomaterials;
Nanotechnologies for Bio- Composite materials;
applications; Thermal analyses.
ICT for Health.
Microscopy lab
BIOMEDICAL LAB.
Surface modification; BIOLAB DISAT-SIMTI –
Characterization of polymeric Thecnology and
materials; Engineered Ceramic
Synthesis of innovative polymers. Materials Laboratories.
BIOLAB - Mechanical Laboratory-
Biomedical engineering field.Lab resources
LISiN – Engineering of Neuromuscolar system.
DET BIOLAB:
Motion analysis
Imaging analysis
Advanced instrument development
Telemedicine
Artificial intelligence in medicine
Minimally Invasive Therapy & Innovation Center(Dip Scienze Chirurgiche,
UNITO), dry-, wet- and virtual- lab for laparoscopy and flexible endoscopy.
C.I.R. Dental School (CIR-DS), excellence center for research, teaching and
support in Odontostomatology field.After the Ph.D
• The medical device market is constantly growing the space for further technological innovations that result
from extensive scientific and medical researches is huge, also thanks to the development of new areas of
research as described above and inter-disciplinary contexts, such as nanotechnology.
• The companies that produce medical devices need to find experts that are able to bring technological innovation.
Similarly, public hospitals and private clinics need qualified personnel capable of interacting with technology
providers to ensure increasingly advanced, competitive and high-quality services.
• The aim of PhD course is to create professionals able to interact with healthcare structures, companies and
universities, and able to work driven by initiative and entrepreneurship, such as to support the consolidation
processes, the evolution and innovation of the local systems of small and medium enterprises in order to strengthen
their competitiveness, especially in the field of new technologies applied to medicine and surgery.After the Ph.D
By basing on available information, there is a positive employment situation for the PhD students.
Some examples:
• 1 PhD student is now « Ricercatore di tipo B» at Università di Torino;
• 1 PhD student is now medical executive at CTO;
• 1 PhD student is a start-up co-founder;
• Researcher at international research centers (TU/e di Eindhoven - NL; RISE Research Institutes of Sweden;
Amsterdam Microbiome Initiative, Imperial College London) or at national and international private company
(USA, Netherlands).
• Clinicians at italian ASL or hospital.Testimonies
Giulia Brachi, Ph.D Giuseppe Isu, Ph.D Federico Amoroso (Ph.D Student)
Contacts:
Link: Prof. Gianluca Ciardelli
http://dottorato.polito.it/bsm/it/presentazione gianluca.ciardelli@polito.it
https://www.dottoratobsmc.unito.it/do/home.pl
Prof. Federico Mussano
federico.mussano@unito.itAfter the Ph.D
PhD in Bioengineering and Medical-Surgical Sciences (XXXII Cycle) Dr Giulia Brachi
Research Field - Biomaterials and Bionanotechnology
Doctoral Research Experience Current Position
Politecnico di Torino (IT), 2016-2019 • Research Associate, Imperial College London
(London, UK), Feb 2020 – Present
Houston Methodist Research Institute (TX, USA), 2017-2018
Italian National Research Council (IT), 2017
Top Universities Ranking:
PhD Awards • 3rd in Europe
• Ermenegildo Zegna Founder’s Scholarship (2017-2018) • 8th in the world
• Paolo Durst Award, Best Doctoral Thesis, GNB (2020)
• Quality Award 2019, Politecnico di Torino (2020)After the Ph.D
PhD in Biomedical Engineering (XXVIII Cycle) Dr Giuseppe Isu
Research Field - Bioreactors for Regenerative Medicine Current Position
prof. Umberto Morbiducci
• R&D Manager, Medics Srl (Torino), June 2019 – Present
Doctoral Research Experience
Scuola Interpolitecnica di Dottorato (IT), 2013-2016
Hannover Medical School (Germany), 2015
PhD Awards • R&D Engineer, University Hospital Basel (Basel,
Switzerland), August 2016 – May 2019
• Best Doctoral Thesis in Bioengineering 2015, Politecnico di
Torino (2016)Facial scanner for surgical and prostheticplanning Geneticfactorsand the risk of peri-implant diseasedevelopment
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