Programme - 53rd Meeting of European Pancreatic Club
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Programme
European Verona - Italy
53rd Meeting Pancreatic June 9-11
VERONA
2021
of the Club 2021
TABLE OF CONTENTS
WELCOME page 3
COMMITTEES page 4
USEFUL INFORMATION page 5
CME CREDITS page 7
PROGRAMME OVERVIEW page 8
SCIENTIFIC PROGRAMME
WEDNESDAY, JUNE 9 page 9
THURSDAY, JUNE 10 page 11
FRIDAY, JUNE 11 page 15
INDUSTRY SUPPORTED SYMPOSIA page 20
POSTERS page 23
ACKNOWLEDGEMENTS page 40
www.epc2021.com 2European Verona - Italy
53rd Meeting Pancreatic June 9-11
VERONA
2021
of the Club 2021
TABLE OF CONTENTS
WELCOME
Dear Colleagues
The European Pancreatic Club in 2021 celebrates its 53rd Annual Meeting that attracts over
600 delegates from 22 countries, consisting of pancreatic specialists, among them surgeons,
endoscopists, gastroenterologists, oncologists, endocrinologists, pathologists, neuroendocrine
doctors and scientists. The 53rd meeting will be a particularly special opportunity to promote
communication between basic and clinical scientists in Europe interested in the pancreas
and its disorders. The official language of the meeting is English.
This would have been the first time for the meeting to be held in Verona, a UNESCO world
heritage site with more than two thousand years of history nestled in northern wine country at
the foot of the Dolomiti Mountains and coddled by the meandering curves of the Adige river.
Unfortunately, the ongoing Covid situation necessitates a virtual conference for 2021.
The 2020 Paris virtual meeting was a great success, and we hope to continue on those lines
in the other romantic European city, which is the home of Shakespeare’s Romeo and Juliet,
and while in 2021 we cannot welcome you here, there is always an open invitation to all EPC
members to visit us.
The organizing committee has put together an exciting program that consists of keynote
lectures providing an overview of developments in the field of pancreatology from microbiota
to artificial intelligence. Multidisciplinary thematic symposia will focus on pancreatic cancer,
neuroendocrine tumours, cystic lesions, and pancreatitis. Advances in precision medicine for
pancreatic tumours will be discussed as part of complete cancer care including psychology
and palliative care.
The symposia will be integrated with oral abstract presentations and poster sessions, covering
many different aspects of pancreatic biology and disease.
This year’s program is a basic science program while never losing sight of the clinical
applications and so we are proud that our pre-meeting basic science workshop will focus on
new models for therapeutic selection.
Aldo Scarpa
EPC President
www.epc2021.com 3European Verona - Italy
53rd Meeting Pancreatic June 9-11
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TABLE OF CONTENTS
COMMITTEES
ORGANIZING COMMITTEE SCIENTIFIC COMMITTEE
(Verona University) Minoti Apte, Australia
Aldo Scarpa, President Claudio Bassi, Italy
Sara Cingarlini Marc Besselink, The Netherlands
Luca Frulloni Marco Bruno, The Netherlands
Rita T. Lawlor Markus Buchler, Germany
Claudio Luchini Gabriele Capurso, Italy
Michele Milella Eithne Costello, UK
Roberto Salvia Anne Couvelard, France
Enrique De Madaria, Spain
ON AIR ORGANIZING COMMITTEE
Christos Dervenis, Greece
Vincenzo Corbo
Thomas Gress, Germany
Stefano Crinò
Peter Hegyi, Hungary
Isabella Frigerio
Johanna Laukkarinen, Finland
Laura Maggino
Matthias Löhr, Sweden
Giuseppe Malleo
Julia Mayerle, Germany
Giovanni Marchegiani
Daniel Ohlund, Sweden
Salvatore Paiella
Francisco X Real, Spain
Antonio Pea
Vinciane Rebours, France
Jonas Rosendahl, Germany
Maria Vaccaro, Argentina
Caroline Verbeke, Norway
Laura Wood, USA
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53rd Meeting Pancreatic June 9-11
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USEFUL INFORMATION
CONGRESS FORMAT
WORKSHOP & CONGRESS SESSIONS
All session presentations have been pre-recorded and will be broadcasted in the congress platform, during
the live congress days. Discussion of all session presentations will be live and will be organized with all the
Speakers, Chairpersons and Discussants at the end of each session. Only for oral abstract presentations (code
CO+number+title) and poster discussions (code PD+number+title) discussion will be done immediately after
each presentation. A chat box will enable participants to make questions. All sessions will run at Central
European Summer Time (CEST).
SPONSORED SYMPOSIA
Sponsored Symposia will run during the congress days 10 and 11 June as indicated in the programme.
POSTER PRESENTATIONS
All uploaded posters will be published in the Poster Area room of the congress platform. Posters will be displayed
vertically oriented on participants’ pc or mobile phone. Audio file, if submitted, will start automatically once
opened the poster.
Each participant will be able to:
• Search a poster using the search field,
• Watch the poster as a printed one on the monitor; once opened the file the audio, if submitted, will start
automatically and can be stopped with the audio player located at the top of the poster list,
• Zoom in/out to see the details;
• Write messages or questions by e-mail (if any) to the Presenting Author
(Presenting Author have been allowed to add his/her e-mail address at the end of the pdf of the poster for this
purpose).
CONGRESS PLATFORM
The background of the rooms of the EPC 2021 congress platform will represent “Palazzo della Gran Guardia”
which was supposed to be the venue of the EPC 2021 in presence.
Once log-in participants will enter in the HOME PAGE, section of “Palazzo della Gran Guardia” from where you
can move to all the rooms of the platform:
LOGGIATO - ORGANIZING SECRETARIAT & HELP DESK
• Help desk - to contact the organizing secretariat for urgent issue
• Congress programme
• Video platform tutorial
• Abstract book
AUDITORIUM - PLENARY ROOM
Plenary room where live sessions will run.
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USEFUL INFORMATION
CME CREDITS
CME evaluation form to be filled in order to request EACCME credits.
SALA BUVETTE - POSTER AREA
Poster presentations.
PIANO NOBILE - EXHIBITION
• Chat room among participants
• Exhibition area
Some of the virtual booths have the possibility to reserve 15 minutes video chat one-to-one with the staff person
indicated. Participants can book only one slot per day and will receive a notice in the platform to confirm that
the slot is confirmed.
If you cannot see the notice, 5 minutes before the meeting starts, under the picture of the staff person, you can
find a button “GO TO VIDEOCALL” to open the videochat.
ON DEMAND
All sessions will be recorded and available on the platform in the “AUDITORIUM” from Wednesday, June 16 at
11:00 CEST until December 19, 2021.
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CME CREDITS
EACCME
EUROPEAN ACCREDITATION COUNCIL FOR CONTINUING MEDICAL EDUCATION
The 53rd Meeting of the European Pancreatic Club, 10/06/2021-11/06/2021 has
been accredited by the European Accreditation Council for Continuing Medical
Education (EACCME®) with 15 European CME credits (ECMEC®s). Each medical
specialist should claim only those hours of credit that he/she actually spent in the
educational activity.
Through an agreement between the Union Européenne des Médecins Spécialistes and the American Medical
Association, physicians may convert EACCME® credits to an equivalent number of AMA PRA Category 1
CreditsTM. Information on the process to convert EACCME® credit to AMA credit can be found at
www.ama-assn.org/education/earn-credit-participation-international-activities.
Live educational activities, occurring outside of Canada, recognised by the UEMS-EACCME® for ECMEC®s are
deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification
Program of the Royal College of Physicians and Surgeons of Canada.
The workshop day, June 9, 2021, has not been accredited.
The evaluation form to be filled in order to claim credits will be available in the congress platform.
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53rd Meeting Pancreatic June 9-11
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PROGRAMME OVERVIEW
WEDNESDAY, JUNE 9, 2021
10:00
Opening remarks
10:15
10:15
Cancer Microenvironment
NOT ACCREDITED
WORSKHOP
11:45
11:45
Disease Models
12:30
12:30
Break and Industry Sponsored Symposium
13:45
13:45
Immune Signalling
14:30
14:30 Pathology, Genomics and Artificial
16:30 Intelligence
THURSDAY, JUNE 10, 2021 FRIDAY, JUNE 11, 2021
8:30
Opening Ceremony and Introduction
8:45 8:30
Acute and Chronic Pancreatitis
8:45 10:20
Pancreas Cancer: Yesterday and Tomorrow
9:45
9:45 Round Table: Patient-centred research and 10:20
Post surgical pancreatitis
10:50 care 10:50
10:50 10:50
Break Break
11:00 11:00
11:00
Biliary Pancreatitis
11:55
11:00 11:55
Ductal Adenocarcinoma Poster Discussion Session
12:55 12:25
CONGRESS
12:25
Lifetime achievement award lecture
12:55
12:55 12:55
Break and Industry Sponsored Symposium Break and Industry Sponsored Symposium
14:15 14:15
14:15 14:15
Poster Discussion Session Poster Discussion Session
14:45 14:45
14:45 14:45
Cystic Lesions to Ductal Carcinoma Precision medicine
16:20 16:20
16:20 16:20
Break Break
16:30 16:30
16:30 16:30
Genomic evolution of PDAC Best Abstract presentations
17:00 17:15
17:00 17:15
Poster Discussion Session Best Poster presentations
17:30 17:30
17:30
Youppie Lectures and Awards
17:30 18:30
General assembly
19:00 18:30
Closing - Welcome to KIEV
18:45
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SCIENTIFIC PROGRAMME
WEDNESDAY, JUNE 9, 2021
NOT ACCREDITED
10:00-10:15 OPENING REMARKS
A. Scarpa (Italy)
10:15-11:45 SESSION: CANCER MICROENVIRONMENT
10:15-10:30 Cancer associated fibroblasts
C. Bousquet (France)
10:30-10:45 Extra Cellular Matrix
SCIENTIFIC PROGRAMME WORSKHOP
D. Öhlund (Sweden)
10:45-11:00 Therapeutic Targeting of Stromal Components
A. Neese (Germany)
11:00-11:15 Microbiome
N. Malats (Spain)
11:15-11:45 Round Table (QA)
Discussants: D. Chang (UK), H. Kocher (UK), T. Gress (Germany)
11:45-12:30 SESSION: DISEASE MODELS
11:45-12:00 In vivo models of PDAC
J. Siveke (Germany)
12:00-12:15 In vitro models of human PDAC
V. Corbo (Italy)
12:15-12:30 Discussion
Discussants: V. Bronte (Italy), F X. Real (Spain)
12:30-13:45 BREAK
13:45-14:30 SESSION: IMMUNE SIGNALLING
13:45-14:00 Interferon signalling and cancer subtypes
E. Espinet (Germany)
14:00-14:15 Immune evasion mechanisms
V. Bronte (Italy)
14:15-14:30 Discussion
Discussants: V. Bronte (Italy), F X. Real (Spain)
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WEDNESDAY, JUNE 9, 2021
14:30-16:30 SESSION: PATHOLOGY, GENOMICS AND ARTIFICIAL INTELLIGENCE
14:30-15:00 Pathology in three dimensions
R.H. Hruban (USA)
15:00-15:30 Genomics
S. Gallinger (Canada)
15:30-16:00 Artificial intelligence
D. Chang (UK)
16:00-16:30 Debate round table: is the time of pathologists over?
Morphology vs molecular and artificial intelligence
Discussants: A. Scarpa (Italy), A. Biankin (UK)
SCIENTIFIC PROGRAMME WORSKHOP
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THURSDAY, JUNE 10, 2021
08:30-08:45 OPENING CEREMONY AND INTRODUCTION
Chairpersons: A. Scarpa (Italy), M. Löhr (Sweden)
08:45-09:45 SESSION: PANCREAS CANCER: YESTERDAY AND TOMORROW
Chairpersons: M. Löhr (Sweden), C. Bassi (Italy)
08:45-09:10 Radical Surgery in PDAC in the next decade
M. Büchler (Germany)
09:10-09:35 Early morning thoughts on the next decade of pancreatic cancer research
F X. Real (Spain)
09:35-09:45 Discussion with Q&A
SCIENTIFIC PROGRAMME CONGRESS
09:45-10:50 SESSION: ROUND TABLE: PATIENT-CENTRED RESEARCH TO CARE
Chairpersons: T. Golan (Israel), S. Crippa (Italy)
09:45-09:55 Today patients expection: surgery
M. Besselink (The Netherlands)
09:55-10:05 Today patients expectations: oncology
M. Milella (Italy)
10:05-10:15 Acceleration of research to meet patients expectations
N. Zeps (Australia)
10:15-10:25 We’re all in this together - coalitions and multistakeholder collaborations to enhance
cancer care
M. Lawler (UK)
10:25-10:50 Discussion with Q&A
10:50-11:00 BREAK
11:00-12:55 SESSION: DUCTAL ADENOCARCINOMA
Chairpersons: G. Zamboni (Italy), C. Verbeke (Norway)
11:00-11:15 Cancer Heterogeneity
V. Adsay (Turkey)
11:15-11:30 Histopathology and molecules for clinicians
I. Esposito (Germany)
11:30-11:45 Liquid biopsy
C. Chelala, L. Sivapalan (UK)
11:45-11:55 OC-01 Characterization of bicarbonate secretion in human pancreatic ductal organoid
cultures
T. Madacsy (Hungary)
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THURSDAY, JUNE 10, 2021
11:55-12:05 OC-02 Map kinase activity drives a subtype specific subset of CAFS in PDAC
P. Delfino (Italy)
12:05-12:15 OC-03 A novel cell population in the healthy pancreas that shares characteristics with the
most aggressive pancreatic cancer
I. Rooman (Belgium)
12:15-12:25 OC-04 Comparison of 19g vs 22g Fransen EUS-FNB device for patient derived organoid
yield from primary pancreatic cancer: a prospective controlled study
P. Allawadhi (Germany)
12:25-12:35 OC-05 Unravelling the role of lymph node metastases in PDAC progression
E. Fiorini (Italy)
12:35-12:45 OC-06 Preoperative risk stratification of postoperative pancreatic fistula: training and
external validation of a risk-tree predictive model for pancreatoduodenectomy
SCIENTIFIC PROGRAMME CONGRESS
G. Perri (Italy)
12:45-12:55 Research in Context Round Table
Discussants: J. Siveke (Germany), T. Gress (Germany)
12:55-14:15 BREAK AND INDUSTRY SATELLITE SYMPOSIUM - see details page 20
14:15-14:45 POSTER DISCUSSION SESSION
Chairpersons: R. Salvia (Italy), D. Chang (UK)
14:15-14:18 PD-01 Tumor specific changes of the gut microbiome in distinct murine pancreatic cancer
models
T. Kaune (Germany)
14:18-14:21 PD-02 A dual inhibitor (metavert) of GSK3b and HDACs in combination with
chemotherapeutics improve therapy efficacy in pancreatic cancer cells and human PDAC
organoids
J. An (Germany)
14:21-14:24 PD-03 Prognostic role of circulating tumor DNA in pancreatic adenocarcinoma - a meta-
analysis
S. Bunduc (Hungary)
14:24-14:27 PD-04 Reprogramming of glutamine metabolism by epigenetic modifier ISD1 regulates
chemotherapy resistance in PDAC
Y. Zhao (Germany)
14:27-14:30 PD-05 Tlr7 inhibition attenuates proliferation of pancreatic cancer cells, but global
knockout does not lead to enhanced survival in genetic mouse models of PDAC
M. Tatura (Germany)
14:30-14:33 PD-06 Modulation of RNA splicing as a novel strategy against pancreatic cancer
M. Capula (Italy)
14:33-14:36 PD-07 Pancreatic cancer patient-derived xenograft (PDX) RNAseq analyses to unravel the
stromal impact on gemcitabin resistance acquisition
J. Raffenne (France)
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THURSDAY, JUNE 10, 2021
14:36-14:39 PD-08 Modelling evolution of PDAC towards aggressive phenotypes using the organoid
culture system
A. Malinova (Italy)
14:45-16:20 SESSION: CYSTIC LESIONS TO PDAC
Chairpersons: V. Adsay (Turkey), L. Brosens (The Netherlands)
14:45-15:05 Morphologic and molecular progression
R. Hruban (USA)
15:05-15:15 OC-07 Immunological microenvironment of precursor lesions of pancreatic ductal
adenocarcinoma
M. Schulte (Germany)
15:15-15:25 OC-08 Surgery following observation of branch-duct IPMN reveals dynamic predictors
SCIENTIFIC PROGRAMME CONGRESS
of malignancy: significance of cyst stability vs. progression. results of the “CROS”
multicentric study
T. Pollini (Italy)
15:25-15:35 OC-09 The diagnostic value of pancreatic juice protein biomarkers for pancreatic cancer
detection
I. Levink (The Netherlands)
15:35-15:45 OC-10 Resectability is in the eye of the observer. A multicentre, blinded, prospective
assessment of NCCN resectability status classification for pancreatic cancer
F. Giannone (Italy)
15:45-15:55 OC-11 Gata4 and Gata6 cooperate to drive tumor biology and patient outcome in human
PDAC
M. P. De Andres (Spain)
15:55-16:05 OC-12 Appraisal of the American Joint Committee on Cancer staging parameters in patients
undergoing resection after neoadjuvant treatment for pancreatic ductal adenocarcinoma
L. Maggino (Italy)
16:05-16:20 Research in Context Round Table
Discussants: S.-M. Hong (South Korea), A. Singhi (USA)
16:20-16:30 BREAK
16:30-17:00 LECTURE: GENOMIC EVOLUTION OF PDAC
Chairperson: A. Scarpa (Italy)
Speaker: R. Rad (Germany)
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THURSDAY, JUNE 10, 2021
17:00-17:30 POSTER DISCUSSION SESSION
Chairpersons: R. Salvia (Italy), D. Chang (UK)
17:00-17:03 PD-09 Clinical utility of 3D CT radiomics signature in evaluating Pan-NEN grade
C. Ingaldi (Italy)
17:03-17:06 PD-10 Association of genetic variants affecting micrornas and pancreatic cancer risk
Y. Lu (Germany)
17:06-17:09 PD-11 Solid pseudopapillary neoplasm of the pancreas and abdominal desmoid tumor in a
patient carrying two different BRCA2 germline mutations
A. Mafficini (Italy)
17:09-17:12 PD-12 Identification of molecular immune-metabolic profiles in pancreatic cancer
F. Marchesi (Italy)
SCIENTIFIC PROGRAMME CONGRESS
17:12-17:15 PD 13 Downstaging chemotherapy for locally advanced and borderline resectable
pancreatic ductal adenocarcinoma
E. Asplund (Sweden)
17:15-17:18 PD-14 Impact of histological response after neoadjuvant therapy on podocalyxin as a
prognostic marker in pancreatic cancer
A. Eurola (Finland)
17:18-17:21 PD-15 How people with pancreatic cancer cope: findings from a scoping review
P. Ristau (Germany)
17:21-17:24 PD-16 Mirna biomarker candidates in pancreatic cystic fluids
C. Driescher (Germany)
17:30-19:00 GENERAL ASSEMBLY
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FRIDAY, JUNE 11, 2021
08:30-10:20 SESSION: ACUTE AND CHRONIC PANCREATITIS
Chairpersons: L. Frulloni (Italy), P. Levy (France)
08:30-08:45 Where are we now
E. De Madaria (Spain)
08:45-08:55 OC-13 Laparoscopic versus EUS-guided gastroenterostomy for gastric outlet obstruction:
an international multicenter propensity score-matched comparison
G. Vanella (Italy)
08:55-09:05 OC-14 TRPV6 functionally defective variants are associated with chronic pancreatitis in
non-alcoholic early-onset Polish and German patients
A. M. Rygiel (Poland)
09:05-09:15 OC-15 Common CASR polymorphisms do not increase chronic pancreatitis risk
SCIENTIFIC PROGRAMME CONGRESS
A. Takáts (Hungary)
09:15-09:25 OC-16 The genetic risk factor cel-hyb causes chronic pancreatitis in mice
K. Fjeld (Norway)
09:25-09:35 OC-17 SARS-COV-2 infection in acute pancreatitis increases disease severity and 30 day
mortality: results of the Covid pan collaborative study
G. Mohammadi-Zaniani (UK)
09:35-09:45 OC-18 How to predict microlithiasis in idiopathic pancreatitis – a machine learning
derived tool
M. Zorniak (Germany)
09:45-09:55 OC-19 Postponed or immediate drainage of infected necrotizing pancreatitis (pointer): a
multicenter randomized trial
L. Boxhoorn (The Netherlands)
09:55-10:05 OC-20 Interplay of ORAI1 Ca2+ channel and cystic fibrosis transmembrane conductance
regulator (CFTR) in epithelial physiology
Á. Varga (Hungary)
10:05-10:20 Research in Context Round Table
Discussants: G. Zamboni (Italy), P. Hegyi (Hungary)
10:20-10:50 SESSION: POST-PANCREASECTOMY ACUTE PANCREATITIS (PPAP):
THE NEW KID ON THE BLOCK
Chairpersons: J. Neoptolemos (Germany), R. Salvia (Italy)
10:20-10:30 From a gut feeling to evidence
S. Connor (New Zealand)
10:30-10:40 The ISGPS definition and grading
E. Bannone (Italy)
10:40-10:50 Discussion with Q&A
10:50-11:00 BREAK
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FRIDAY, JUNE 11, 2021
11:00-11:55 SESSION: BILIARY PANCREATITIS
Chairpersons: J. Neoptolemos (Germany), R. Salvia (Italy)
11:00-11:10 Pathophysiology
M. Lerch (Germany)
11:10-11:20 Consensus definitions - results of intl. expert survey
J. Mayerle (Germany)
11:20-11:30 OC-21 Extension: long-term follow-up study of an endoscopic versus surgical step-up
approach for infected necrotizing pancreatitis
A. Onnekink (The Netherlands)
11:30-11:40 OC-22 Optimal timing of cholecystectomy after necrotising biliary pancreatitis
H. Timmerhuis (The Netherlands)
SCIENTIFIC PROGRAMME CONGRESS
11:40-11:55 Research in Context Round Table
Discussants: T. Gress (Germany), H. van Santvoort (The Netherlands)
11:55-12:25 POSTER DISCUSSION SESSION
Chairpersons: E. Costello (UK), M. Besselink (The Netherlands)
11:55-11:58 PD-17 Bicarbonate defective CFTR variants in chronic pancreatitis: a meta-analysis
G. Berke (Hungary)
11:58-12:01 PD-18 Differentiating infected pancreatic necrosis from sterile pancreatic necrosis with CT
radiomics features
S. Rumovskaya (Russia)
12:01-12:04 PD-19 The role of ORAI1 Ca2+ channel in the pancreatic ductal epithelial cells under
pathophysiological conditions
N. Csákány-Papp (Hungary)
12:04-12:07 PD-20 Reduced pancreatic exocrine function in chronic pancreatitis is associated with
pancreatic fibrosis assessed by MRI
E. Steinkohl (Denmark)
12:07-12:10 PD-21 Adherence to European guidelines in treatment and management of pancreatic
exocrine insufficiency in chronic pancreatitis patients
M. Khan (Sweden)
12:10-12:13 PD-22 Thiopurines disturb pancreatic homeostasis through the inhibition of ductal chloride
and bicarbonate secretion in mice
B. Tél (Hungary)
12:13-12:16 PD-23 Loss of muscle mass and strength in experimental chronic pancreatitis
J. Doller (Germany)
12:16-12:19 PD-24 The role of CFTR mutations in acute biliary pancreatitis
Á. R. Martonosi (Hungary)
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FRIDAY, JUNE 11, 2021
12:25-12:55 LIFETIME ACHIEVEMENT AWARD LECTURE CEREMONY
Chairpersons: M. Löhr (Sweden), C. Dervenis (Greece)
Of Pancreas and Blues
C. Bassi (Italy)
12:55-14:15 BREAK AND INDUSTRY SPONSORED SYMPOSIA - see details page 20
14:15-14:45 POSTER DISCUSSION SESSION
Chairpersons: E. Costello (UK), M. Besselink (The Netherlands)
14:15-14:18 PD-25 Evaluation of currently available screening methods for cystic fibrosis-related
diabetes
SCIENTIFIC PROGRAMME CONGRESS
V. Izsak (Hungary)
14:18-14:21 PD-26 Establishment and screening of in vivo CRISPR/CAS9 in pancreatic cancer
organoids
M. Miquel (Germany)
14:21-14:24 PD-27 Identification of recessively inherited genetic variants for pancreatic cancer risk
Y. Lu (Germany)
14:24-14:27 PD-28 3D systems to study pancreatic ductal adenocarcinoma (PDAC). Comparison of the
most referenced models using a bibliometric approach
M. Ponz-Sarvise (Spain)
14:27-14:30 PD-29 Characterizing 2d and 3d organoid cultures derived from mouse and human
pancreas specimens
V. Szabó (Hungary)
14:30-14:33 PD-30 Preoperative diabetes mellitus in patients undergoing pancreatic surgery
M. Stott (UK)
14:33-14:36 PD-31 A Combination of the proteins plasma thrombospondin-2 and ca19-9 improves the
diagnosis of pancreatic cancer and distal cholangiocarcinoma
L. Boyd (The Netherlands)
14:36-14:39 PD-32 Recruitment pathways in the UK early detection initiative (UK-EDI) for pancreatic
cancer study
M. Stott (UK)
14:45-16:20 SESSION: PRECISION MEDICINE
Chairpersons: A. Scarpa (Italy), T. Gress (Germany)
14:45-15:00 Are we there yet? - Surgery
M. Falconi (Italy)
15:00-15:15 Are we there yet? - Oncology
E. O’Reilly (USA)
15:15-15:30 Artificial intelligence
D. Chang (UK)
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FRIDAY, JUNE 11, 2021
15:30-15:40 OC-23 Detection of serum N-glycans based on changes over time for earlier detection of
pancreatic cancer in high-risk individuals
I. Levink (The Netherlands)
15:40-15:50 OC-24 Circulating TP53 mutations are predictive and prognostic biomarkers in pancreatic
cancer patients treated with Folfirinox chemotherapy
F. Van Der Sijde (The Netherlands)
15:50-16:00 OC-25 Individualized low-dose drug combinations in pancreatic ductal adenocarcinoma: a
phosphoproteomic approach
A. Vallés Martí (The Netherlands)
16:00-16:10 OC-26 Leukocyte-DNA methylome explains a large proportion of the risk variability of
pancreatic cancer
E. López De Maturana (Spain)
SCIENTIFIC PROGRAMME CONGRESS
16:10-16:20 OC-27 Galectin-4 driven immunosuppression in pancreatic ductal adenocarcinoma
T. Lidström (Sweden)
16:20-16:30 BREAK
16:30-17:15 BEST ABSTRACT PRESENTATIONS
Chairpersons: F. X. Real (Spain), M. Bruno (The Netherlands)
16:30-16:45 OC-28 Artificial pancreas - bihormonal closed loop glucose control - versus current care
after total pancreatectomy (APPEL5+): outpatient randomized controlled crossover trial
C. Van Veldhuisen (The Netherlands)
16:45-17:00 OC-29 The biphasic role of Sema3a in PDAC progression
F. Lupo (Italy)
17:00-17:15 OC-30 Tailored ruthenium complexes target pancreatic cancer stem cells through
inhibition of mitochondrial DNA transcription
B. Sainz, Jr. (Spain)
17:15-17:30 BEST POSTER PRESENTATIONS
Chairpersons: M. Bruno (The Netherlands), F. X. Real (Spain)
17:15-17:20 PD-33 MTORC1 plays an important role in generating inflammatory desmoplastic reaction
in pancreatic ductal adenocarcinoma
Y. Yu (Germany)
17:20-17:25 PD-34 Molecular characterization of cellular heterogeneity in pancreatic ductal
adenocarcinoma by transcriptome profiling
P. Di Chiaro (Italy)
17:25-17:30 PD-35 Whole genome sequencing identifies rare variants enriched in cancer related genes
in first-degree relatives of familial pancreatic cancer
M. Tan (Denmark)
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FRIDAY, JUNE 11, 2021
17:30-18:30 YOUPPIE PRESENTATIONS AND AWARDS
Chairpersons: G. Marchegiani (Italy), H. Sternby (Sweden)
17:30-17:40 International survey on guidelines application for cystic neoplasms
G. Marchegiani (Italy)
17:40-17:50 Endoscopic papillectomy vs. pancreaticoduodenectomy for ampullary lesions:
a propensity-scored matching analysis of the ESAP study
M. Hollenbach (Germany)
17:50-18:00 Infected necrotizing pancreatitis: treatment based on recent evidence
L. Boxhoorn (The Netherlands)
18:00-18:10 Targeted therapies for pancreatic cancer: an overview
P. Acedo (UK)
SCIENTIFIC PROGRAMME CONGRESS
18:10-18:20 Pancreatic exocrine insufficiency in pancreatic cancer
S. Powell-Brett (UK)
18:20-18:30 Total pancreatectomy vs anastomosis in high-risk pancreatic remnant after
pancreaticoduodenectomy: from retrospective studies towards a clinical trial
G. Perri (Italy)
18:30-18:45 CLOSING
Welcome to EPC 2022 Kiev
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INDUSTRY SUPPORTED SYMPOSIA
VIATRIS SPONSORED SYMPOSIUM
THURSDAY, JUNE10, 2021
13:00-14:00 PANCREATIC EXOCRINE INSUFFICIENCY IN PANCREATIC CANCER: BRIDGING THE GAP
BETWEEN RESEARCH AND CLINICAL PRACTICE
Chairperson: J. E. Domínguez-Muñoz (Spain)
13:00-13:05 Introduction
J. E. Domínguez-Muñoz (Spain)
13:05-13:15 Which patients with pancreatic cancer develop PEI and how are they currently treated?
The Spanish experience
INDUSTRY SUPPORTED SYMPOSIA
J. E. Domínguez-Muñoz (Spain)
13:15-13:30 Variation and under use of PERT in pancreatic cancer: results of the RICOCHET British
audit
K. Roberts (United Kingdom)
13:30-13:45 PERT in pancreatic cancer: Pitfalls and opportunities in clinical research and practice
G. Capurso (Italy)
13:45-14:00 Q&A
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INDUSTRY SUPPORTED SYMPOSIA
IPSEN SPONSORED SYMPOSIUM
FRIDAY, JUNE 11, 2021
13:00-13:30 NEUROENDOCRINE NEOPLASMS: SOMATOSTATIN AND BEYOND
Chairperson: C. Bassi (Italy)
13:00-13:05 Introduction
C. Bassi (Italy)
13:05-13:15 Pathology and molecules
A. Scarpa (Italy)
13:15-13:25 Update on therapy
INDUSTRY SUPPORTED SYMPOSIA
N. Fazio (Italy)
13:25-13:30 Q&A
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INDUSTRY SUPPORTED SYMPOSIA
LEICA-BIOSYSTEMS SPONSORED SYMPOSIUM
FRIDAY, JUNE 11, 2021
13:35-14:05 TOOLS OF THE TRADE: MULTIPLEXED DIGITAL PATHOLOGY
Chairperson: M. Leung (Germany)
13:35-13:40 Introduction
M. Leung (Germany)
13:40-13:50 Multiplexing immunohistochemistry for applied research
A. Scarpa (Italy)
13:50-14:00 Digital imaging for biobanking and artificial intelligence
INDUSTRY SUPPORTED SYMPOSIA
R. T. Lawlor (Italy)
14:00-14:05 Q&A
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LIST OF POSTERS
All uploaded posters will be published in the Poster Area room of the congress platform. Posters will be displayed vertically
oriented on participants’ pc or mobile phone. Audio file can be activated if uploaded.
Each participant will be able to:
1. Search a poster using the keywords: topic, title, author, number
2. Watch the poster as a printed one on the monitor;
3. Listen to the audio file (if any);
4. Zoom in/out to see the details;
5. Write messages or questions by e-mail (if any) to the Presenting Author
(Presenting Author have been allowed to add his/her e-mail address at the end of the pdf of the poster for this purpose).
Highlighted posters with PD number, will be also presented in the POSTER DISCUSSION SESSIONS in the scientific programme.
01. ACUTE AND CHRONIC PANCREATITIS EXPERIMENTAL
P.001 THIOPURINES DISTURB PANCREATIC HOMEOSTASIS THROUGH THE INHIBITION OF DUCTAL CHLORIDE AND BICARBONATE
SECRETION IN MICE *PD-22
B. Tél, N. Papp, B. Deaák, P. Hegyi, G. Veres, J. Maléth, P. Pallagi
P.002 FOXP3+/CD25+ REGULATORY T-CELLS INFLUENCE MACROPHAGE DIFFERENTIATION AND REGULATE TISSUE REMODELING
IN A CHRONIC MODEL OF PANCREATITIS
J. Glaubitz, A. Wilden, F.U. Weiss, M.M. Lerch, A.A. Aghdassi, M. Sendler
P.003 LOSS OF IRAK-M AMELIORATES LOCAL DAMAGE DURING ACUTE PANCREATITIS BUT INCREASES SYSTEMIC
LIST OF POSTERS
INFLAMMATION
F. Thiel, J. Glaubitz, A. Wilden, F.U. Weiss, M.M. Lerch, A.A. Aghdassi, M. Sendler
P.004 THE WAY TO INFECTED NECROSIS DURING SEVERE ACUTE PANCREATITIS: HOW REGULATORY T-CELLS IMPACT ON THE
INTESTINAL BARRIER FUNCTION
J. Glaubitz, A. Wilden, F.U. Weiss, F. Frost, A.A. Aghdassi, M. Sendler
P.005 CCR2+ MONOCYTES, NOT NEUTROPHILS, ARE RESPONSIBLE FOR LUNG AND KIDNEY DAMAGE DURING SEVERE ACUTE
PANCREATITIS IN MICE
A. Wilden, J. Glaubitz, F.U. Weiss, M.M. Lerch, A.A. Aghdassi, M. Sendler
P.006 DABIGATRAN TO TREAT PANCREATITIS: PRECLINICAL STUDIES
Z.G. Pesei, B.C. Nemeth, M. Sahin-Toth
P.007 PANCREATIC AND PERIPANCREATIC FLUID COLLECTIONS IN ACUTE PANCREATITIS: A MODERN APPROACH TO THE
TREATMENT
I. Kryvoruchko
P.008 PATHOPHYSIOLOGY OF THE FORMATION OF AUTOIMMUNE INFLAMMATION IN THE GASTRIC AND DUODENAL MUCOSA
IN PATIENTS WITH ALCOHOLIC PANCREATITIS
I. Trubitsyna, L. Vinokurova, T. Tarasova, N. Vorobyova, K. Lesko, A. Smirnova, G. Varvanina
P.009 THE PANCREAS HAS HIGH IMMUNE TOLERANCE (PATHOPHYSIOLOGY)
I. Trubitsyna, Y. Orlova, K. Lesko, G. Varvanina
P.010 LOSS OF MUSCLE MASS AND STRENGTH IN EXPERIMENTAL CHRONIC PANCREATITIS *PD-10
J. Doller, M. Sendler, F.U. Weiss, M.L. Wiese, J. Fielitz, M. Delcea, S. Görs, C. Metges, L. Ehlers, K. Bannert, R. Jaster,
M. Lerch, A. Aghdassi
P.011 THE ROLE OF ORAI1 CA2+ CHANNEL IN THE PROGRESSION OF CHRONIC PANCREATITIS
B. Deák, P. Pallagi, N. Papp, M. Görög, V. Szabó, B. Tél, Á. Varga, T. Madácsy, P. Hegyi, J. Maléth
P.012 THE ROLE OF ORAI1 CA2+ CHANNEL IN THE PANCREATIC DUCTAL EPITHEL CELLS UNDER PATHOPHYSOLOGICAL
CONDITIONS *PD-19
N. Csákány-Papp, P. Pallagi, M. Görög, Á. Varga, T. Madácsy, B. Deák, B. Tél, P. Hegyi, J. Maleth
P.013 OPTIMIZATION OF DOSE LEVELS OF ORALLY ADMINISTERED PANCREATIC ENZYME SUPPLEMENTS IN THE DYNAMIC
IN-VITRO GASTROINTESTINAL MODEL TINY-TIM
M.L. Orera-Peña, H. De Voogd, R. Schilderink, A. Maathuis, S. Bellmann
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P.014 PANCREATIC FLUID LIPOCALIN-2 LEVELS ARE ALTERED IN EARLY CHRONIC PANCREATITIS PATIENTS AND ARE RELATED
TO THE EXOCRINE PANCREATIC DYSFUNCTION DEGREE AND SMOKING
S. Leal-Lopez, M.J. Otero-Fraga, J. Iglesias-Garcia, J. Lariño-Noia, L. Nieto-Garcia, A. Alvarez-Castro, D. De La Iglesia-Garcia,
S. Lojo-Rocamonde, Y. Pazos-Randulfe, J.E. Dominguez-Muñoz
02. ACUTE AND CHRONIC PANCREATITIS CLINICAL
P.015 WITHDRAWN
P.016 WITHDRAWN
P.017 THE RELATIONSHIP BETWEEN IBS-LIKE SYNDROME AND EXACERBATION OF CHRONIC PANCREATITIS
L. Zhuravlyova, Y. Shekhovtsova
P.018 THE INFLUENCE OF INULIN ON WEIGHT MAINTENANCE, APPETITE AND BODY FAT IN PATIENTS WITH CHRONIC
PANCREATITIS AND PREDIABETES
L. Zhuravlyova, Y. Shekhovtsova
P.019 THE RELATIONSHIP BETWEEN THE PRESENCE OF ATHEROSCLEROTIC PLAQUE AND VASPIN LEVEL IN PATIENTS WITH
TYPE 2 DIABETES MELLITUS AND CHRONIC PANCREATITIS
L. Zhuravlyova, D. Pylov, A. Zhuravlyova
P.020 THE INFLUENCE OF ALPHA-LIPOIC ACID ON ADIPOCYTOKINE STATUS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
AND CHRONIC PANCREATITIS
LIST OF POSTERS
L. Zhuravlyova, D. Pylov
P.021 LACTATED RINGER’S SOLUTION DOES NOT REDUCE INFLAMMATION IN ACUTE PANCREATITIS - A META-ANALYSIS
Z. Vinkó, N. Gede, P. Hegyi, A. Párniczky, K. Ocskay
P.022 METABOLIC ASSOCIATED FATTY LIVER DISEASE IS ASSOCIATED WITH A MORE SEVERE ACUTE PANCREATITIS:
A PROSPECTIVE COHORT ANALYSIS OF 2053 CASES
S. Váncsa, Z. Sipos, R. Nagy, K. Ocskay, F. Juhász, M. Földi, Á. Vincze, P. Sarlós, J. Bajor, F. Izbéki, M. Papp, Z. Vitális,
J. Hamvas, L. Czakó, N. Faluhelyi, O. Farkas, E. Miklós, A. Mikó, H. Jeno-Péter, M. Macarie, S. Galeev, E. Ramirez Maldonado
V. Sallinen, I. Török, A. Mickevicius, B. Eross, A. Párniczky, A. Szentesi, G. Pár, P. Hegyi
P.023 ALCOHOL CONSUMPTION AND SMOKING ARE DOSE DEPENDENTLY WORSEN THE OUTCOME OF ACUTE PANCREATITIS
A. Szentesi, N. Gede, M. Foldi, S. Kiss, Z. Gyomber, A. Vincze, S. Godi, J. Bajor, B.C. Nemeth, T. Takacs, L. Czako,
F. Izbeki, J. Hamvas, M. Varga, V. Sallinen, M. Macarie, I. Torok, A. Mickevicius, E. Ramirez Maldonado, A. Miseta, T. Nagy,
N. Faluhelyi, P. Kanizsai, D. Pecsi, P. Varju, N. Zadori, P.J. Hegyi, A. Parniczky, P. Hegyi
P.024 REDUCED PANCREATIC EXOCRINE FUNCTION IN CHRONIC PANCREATITIS IS ASSOCIATED WITH PANCREATIC FIBROSIS
ASSESSED BY MRI *PD-20
E. Steinkohl, S. Schou Olesen, A. Mohr Drewes, J. Brøndum Frøkjær
P.025 WITHDRAWN
P.026 ADHERENCE TO EUROPEAN GUIDELINES IN TREATMENT AND MANAGEMENT OF PANCREATIC EXOCRINE INSUFFICIENCY
IN CHRONIC PANCREATITIS PATIENTS *PD-21
M. Khan, W. Rutkowski, M. Vujasinovic, W. Jebril, M. Löhr
P.027 COMPARISON BETWEEN ACUTE PANCREATITIS IN THE EDERLY AND VERY EDERLY PEOPLE
M.L. Ruiz-Rebollo, M.F. Muñoz-Moreno, R. Busta-Nistal, S. Izquierdo-Santervás, M. Durá-Gil
P.028 COMPLICATIONS OF STEP-UP MINI INVASIVE APPROACH OF SURGICAL TREATMENT OF PATIENTS WITH ACUTE
NECROTIZING PANCREATITIS
I. Khomiak, O. Rotar, A. Khomiak, A. Malyk, V. Kropuva, L. Rozhok
P.029 COVID-19 INFECTION IN PATIENTS WITH ACUTE PANCREATITIS - PARTICULARITIES OF CLINICAL PRESENTATION
AND MANAGEMENT
O. Rotar, I. Khomiak, V. Rotar, O. Hrama, M. Fishbach, O. Rak, O. Polyanskyy
P.030 EVALUATION OF CALCIUM AND PHOSPHATE METABOLISM AND MUSCULOSKELETAL SYSTEM IN PATIENTS
WITH CHRONIC PANCREATITIS - PRELIMINARY REPORT
M. Rakowska, A. Mianowska, M. Jaworski, M. Wojcik, P. Pludowski, G. Oracz
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P.031 WITHDRAWN
P.032 AUTOIMMUNE PANCREATITIS FEATURES IN THE RUSSIAN POPULATION: EXPERIENCE OF SINGLE CENTER
A. Okhlobystin, S. Kardasheva, A. Ufimtseva, E. Tsygankova
P.033 THE IMPORTANCE OF SERUM ALBUMIN LEVELS IN ACUTE PANCREATITIS - A PROSPECTIVE, INTERNATIONAL,
MULTICENTER REGISTRY ANALYSIS OF 1149 PATIENTS
K. Ocskay, Z. Vinkó, D. Németh, L. Szabó, J. Bajor, S. Gódi, P. Sarlós, L. Czakó, F. Izbéki, M. Pappa, E. Ramirez Maldonado,
S. Galeev, A. Mikó, B. Eröss, Z. Szakács, M. Imrei, P.J. Hegyi, N. Faluhelyi, O. Farkas, V. Sallinen, P. Kanizsai, A. Miseta,
T. Nagy, R. Hágendorn, Z. Márton, A. Szentesi, P. Hegyi, A. Párniczky
P.034 RECURRENT ACUTE PANCREATITIS PREVENTION BY THE ELIMINATION OF ALCOHOL AND CIGARETTE SMOKING
(REAPPEAR): PROTOCOL OF A RANDMOZIED CONTROLLED TRIAL AND A COHORT STUDY
K. Ocskay, M.F. Juhász, N. Farkas, N. Zádori, L. Szakó, A. Szentesi, B.M. Eröss, E. Miklós, A. Zemplényi, B. Birkás, Á. Csathó,
I. Hartung, T. Nagy, L. Czakó, F. Izbéki, L. Gajdán, L. Czakó, D. Illés, M.V. Marino, M. Papp, A. Miarbella, E. Malecka-Panas,
H. Zatorski, M.-L. Ruiz-Rebollo, G. Capurso, C. Gheroghe, I.A. Saizu, A. Párniczky, P. Hegyi
P.035 SAFE AND EFFECTIVE PROTOCOL TO DISCHARGE PATIENTS IN ACUTE PANCREATITIS
R. Nagy, L. Hanák, K. Ocskay, A. Mikó, P.J. Hegyi, N. Farkas, D. Németh, A. Szentesi, A. Párniczky, P. Hegyi
P.036 STUDY OF THE EARLY PHASE OF CHRONIC PANCREATITIS: RESULTS OF A 2-YEAR FOLLOW-UP OF THE FIRST 133
PATIENTS IN THE GOULASH-PLUS STUDY
A. Mikó, D. Kató, V. Lillik, S. Váncsa, P.J. Hegyi, P. Sarlós, Á. Vincze, N. Faluhelyi, B. Bódis, L. Gajdán, F. Izbéki, P. Hegyi
P.037 THE FLIP STUDY - FLUID RESUSCITATION IN PANCREATITIS
J. Mcgovern, J. Moir, S. Tingle, E. Hawthornwaite, S. Robinson
LIST OF POSTERS
P.038 PROGNOSTIC SCORES IN POST-ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY ACUTE PANCREATITIS:
IS THERE A BETTER OPTION?
V. Macedo Silva, M. Freitas, R. Sousa Magalhães, T. Cúrdia Gonçalves, P. Boal Carvalho, B. Rosa, J. Cotter
P.039 PLEUROPULMONARY PATHOLOGIES IN THE EARLY PHASE OF ACUTE PANCREATITIS CORRELATE WITH DISEASE
SEVERITY
I. Luiken, S. Eisenmann, J. Garbe, J. Dober, W.A. Wohlgemuth, R. Brill, P. Michl, J. Rosendahl, M. Damm
P.040 DIFFERENTIATING INFECTED PANCREATIC NECROSIS FROM STERILE PANCREATIC NECROSIS WITH CT RADIOMICS
FEATURES *PD-18
A. Litvin, S. Rumovskaya, S. Listopad, F. Paramzin, A. Kropinov, A. Kapustina
P.041 FAST-TRACK SURGERY IN SEVERE ACUTE PANCREATITIS USING THE TACTICS STEP-UP APPROACH
A. Drozdova, K. Parkhomenko, V. Vovk, I. Kryvoruchko
P.042 EARLY INDICATORS FOR SEVERITY AND PROGNOSIS IN ACUTE PANCREATITIS
I. Kryvoruchko, A. Drozdova
P.043 OPEN AND MINIMALLY INVASIVE MANAGEMENT OF SEVERE ACUTE PANCREATITIS AND ITS LOCAL COMPLICATIONS:
A 30-YEARS EXPERIENCE IN TWO CENTERS WITH ONE TACTICAL APPROACH
I. Kryvoruchko, V. Boyko, K. Parkhomenko, Y. Ivanova, A. Drozdova
P.044 SCREENING AND DIAGNOSIS OF AUTOIMMUNE PANCREATITIS AND PANCREATIC EXOCRINE FUNCTION IN PATIENTS
WITH PANCREATIC AND AUTOIMMUNE DISEASES
M. Kovacheva-Slavova, J. Genov, B. Golemanov, P. Gecov, B. Vladimirov
P.045 MRCP IN CHILDREN WITH CHRONIC PANCREATITIS - CAN IT REPLACE ERCP AS THE GOLD STANDARD?
E. Kolodziejczyk, E. Jurkiewicz, M. Dadalski, G. Oracz
P.046 RISK PREDICTION MODEL FOR DEVELOPING PANCREATIC NECROSIS
S. Kiss, N. Farkas, P. Fehérvári, L. Pecze, L. Szakó, Á. Vincze, S. Gódi, J. Bajor, J. Czimmer, P. Sarlós, R. Hágendorn,
T. Takács, F. Izbéki, A. Halász, J. Hamvas, M. Varga, S. Crai, A. Mickevicius, Á. Patai, M. Ihász, P. Varjú, N. Faluhelyi,
O. Farkas, A. Miseta, D. Kelemen, R. Papp, P.J. Hegyi, A. Szentesi, A. Párniczky, P. Hegyi
P.047 PANCREATODUODENECTOMY FOR SURGICAL TREATMENT OF PARADUODENAL PANCREATITIS
O. Usenko, I. Khomiak, A. Khomiak, O. Rotar, A. Malik, M. Krol
P.048 PROGNOSTIC SIGNIFICANCE OF EXTENT AND LOCATION OF NECROSIS IN ACUTE NECROTIZING PANCREATITIS
A. Khomiak, I. Khomiak, O. Rotar, A. Malik
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P.049 THE EFFECT OF DIETARY FAT CONTENT ON THE RECURRENCE OF PANCREATITIS - PRE-STUDY PROTOCOL OF THE EFFORT-
RANDOMIZED CONTROLLED TRIAL
M.F. Juhász, Z. Vereczkei, K. Ocskay, L. Szakó, K. Farkas, Z. Szakács, N. Zádori, A. Párniczky, M. Wilschanski, S.J. Pandol,
F. Joly, G. Capurso, F. Izbéki, L. Czakó, M. Papp, P. Hegyi
P.050 PANCREATIC FAMILY HISTORY, RECURRENT AND CHRONIC PANCREATITIS: ANALYSIS OF AN INTERNATIONAL COHORT
OF 2345 ACUTE PANCREATITIS PATIENTS
M.F. Juhász, K. Farkas, A. Szentesi, P. Hegyi, A. Párniczky
P.051 INVALIDITY OF TOKYO CRITERIA FOR CHOLANGITIS AND CHOLECYSTITIS IN ACUTE BILIARY PANCREATITIS:
PRELIMINARY DATA OF AN INTERNATIONAL COHORT ANALYSIS
M.F. Juhász, K. Farkas, V. Jászai, R. Tóháti, R. Molnár, Á. Vincze, A. Szentesi, P. Hegyi, A. Párniczky
P.052 FEASIBILITY OF CEUS AND AI DETECTING THE SEVERITY OF ACUTE PANCREATITIS
A. Gulla, A. Samuilis, R. Raisutis, K. Strupas
P.053 DRUG-INDUCED PANCREATITIS DURING TREATMENT FOR PULMONARY TUBERCULOSIS
N. Gubergrits, A. Klochkov, G. Lukashevich, P. Maisonneuve
P.054 IDIOPATHIC RECURRENT PANCREATITIS IN A YOUNG WOMAN: UNEXPECTED CLUE
N. Gubergrits, N. Monogarova, N. Byelyayeva, G. Lukashevich, P. Fomenko, S. Shpak, E. Bakhchevan
P.055 INCIDENCE OF ACUTE RECURRENT PANCREATITIS IN PATIENTS WITH GILBERT’S SYNDROME
N. Byelyayeva, N. Gubergrits, G. Lukashevich
P.056 FEATURES OF BACTERIAL OVERGROWTH SYNDROME AND ITS TREATMENT IN CHRONIC PANCREATITIS
LIST OF POSTERS
N. Gubergrits, N. Byelyayeva, G. Lukashevich, P. Fomenko
P.057 EFFICACY OF ENDOSCOPIC TREATMENT IN PATIENTS SUFFERING FROM GENETIC PANCREATITIS
E.M. Gabrieletto, A. Amodio, G. De Marchi, V. Bobba, E. Marconato, P. Campagnola, M.C. Conti Bellocchi, S. Di Stefano,
S. Crinò, L. Bernardoni, A. Gabbrielli, L. Frulloni
P.058 THE CHARACTERISTICS AND PROGNOSTIC ROLE OF ACUTE ABDOMINAL ON-ADMISSION PAIN IN ACUTE PANCREATITIS:
A PROSPECTIVE COHORT-ANALYSIS OF 1432 CASES
M. Földi, N. Gede, S. Kiss, Á. Vincze, J. Bajor, I. Szabó, Z. Szepes, F. Izbéki, J. Gervain, J. Hamvas, Z. Vitális, E. Fehér,
S. Crai, V. Sallinen, E. Ramirez Moldando, Á. Meczker, P. Varjú, G. Poropat, D. Stimac, N. Faluhegyi, A. Miseta, T. Nagy,
A. Vereczkei, Z. Márton, P.J. Hegyi, P. Hegyi, A. Párniczky, A. Szentesi
P.059 FINDING PREDICTORS OF AZATHIOPRINE-INDUCED PANCREATITIS IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE
M. Freitas, T. Capela, V. Macedo Silva, C. Arieira, T. Cúrdia Gonçalves, F. Dias de Castro, M.J. Moreira, J. Cotter
P.060 PREVALENCE OF GASTROINTESTINAL BLEEDING IN PANCREATITIS: A SYSTEMATIC REVIEW AND META-ANALYSIS
M.A. Engh, L. Frim, N. Gede, L. Szakó, N. Vörhendi, E. Csiki, P. Hegyi, B. Eröss
P.061 EARLY, LATE OR NO SURGERY FOR THE GROOVE PANCREATITIS? EXPERIENCE OF 86 CASES OF THE CYSTIC DYSTROPHY
OF THE DUODENAL WALL
V. Egorov, R. Petrov, A. Schegolev, E. Dubova, A. Vankovich, A. Dobriakov, N. Schvetz, E. Poputchikova
P.062 RISK OF DEVELOPING PANCREATIC CANCER IN PATIENTS WITH CHRONIC PANCREATITIS
M. Vujasinovic, A. Dugic, P. Maisonneuve, A. Aljic, R. Berggren, N. Panic, R. Valente, R. Pozzi Mucelli, A. Waldthaler,
P. Ghorbani, M. Kordes, H. Hagström, M. Löhr
P.063 THE CLINICAL IMPACT OF AUTOIMMUNE PANCREATITIS AND ULCERATIVE COLITIS ASSOCIATION: A THIRD-LEVEL,
SINGLE-CENTER ITALIAN EXPERIENCE
M.C. Conti Bellocchi, S. Crino’, L. La Monaca, E. Marconato, M. Cattani Mottes, A. Gabbrielli, L. Frulloni
P.064 DIAGNOSTIC AND MANAGEMENT OF ACUTE PANCREATITIS: REVIEW OF MODERN GUIDELINES
S. Chooklin, S. Chuklin
P.065 LUMEN-APPOSING METAL STENTS VERSUS DOUBLE-PIGTAIL PLASTIC STENTS IN THE ENDOSCOPIC STEP-UP APPROACH
FOR INFECTED NECROTIZING PANCREATITIS
L. Boxhoorn, R.C. Verdonk, M.G. Besselink, W. Curvers, S.M. van Dijk, H.M. van Dulleman, E.J. van Geenen, M. Hadithi,
W.L. Hazen, P. Honkoop, J.E. van Hooft, M.A. Jacobs, E. Kouw, S.D. Kuiken, M. Ledeboer, L.E. Perk, J.-W. Poley, R. Quispel,
R. de Ridder, H.C. van Santvoort, H.C. Timmerhuis, B.J. Witteman, D.S. Umans, N.G. Venneman, F.P. Vleggaar, C.J. Sperna
Weiland, M.J. Bruno, P. Fockens, R.P. Voermans
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TABLE OF CONTENTS
P.066 DEFINING ACUTE INFLAMMATION IN CHRONIC PANCREATITIS: A SYSTEMATIC REVIEW
T. Bouca Machado, P. Andrea-Ferreira, J. Bech Pedersen, M. Bau Mortensen, S. Novovic, S. Schou Olesen, A. Mohr Drewes
P.067 EARLY ENTERAL FEEDING IN EVERY CASE COULD BE BENEFICIAL IN ACUTE PANCREATITIS
I. Bosnyak, K. Marta, N. Gede, D. Dohos, A. Vincze, J. Bajor, F. Izbeki, J. Hamvas, M. Varga, S. Godi, B.C. Nemeth, T. Takacs,
L. Czako, M. Papp, E.K. Feher, A. Mickevicius, E. Ramirez Maldonado, V. Sallinen, I. Torok, D. Pecsi, P. Varju, A. Miseta,
T. Nagy, N. Faluhelyi, Z. Marton, P. Kanizsai, A. Parniczky, P. Hegyi, A. Szentesi
P.068 BACTERIAL OVERGROWTH SYNDROME AND EXOCRINE PANCREATIC INSUFFICIENCY IN CHRONIC PANCREATITIS
O. Bondarenko, T. Maksymets, M. Sorochka
P.069 DIFFERENCES IN CLINICAL, SEROLOGICAL AND RADIOLOGICAL FEATURES OF RESECTED AND NON-RESECTED PATIENTS
WITH AUTOIMMUNE PANCREATITIS
T. Appelt, S. Schorn, C. Jäger, G. Kaissis, R. Braren, H. Friess, I.E. Demir, G.O. Ceyhan
P.070 THE INCIDENCE AND ETIOLOGY OF ACUTE PANCREATITIS IN FINLAND HAVE CHANGED - A POPULATION-BASED STUDY
IN 2014-2015
A. Nikkola, J. Nikkola, E. Kari, A. Roponen, A. Tapaninaho, J. Sand, J. Laukkarinen
P.071 ETIOLOGY OF ACUTE PANCREATITIS: HYPERTRIGLYCERIDE-ASSOCIATED ACUTE PANCREATITIS AND ALCOHOL ABUSE
O. Dronov, I. Kovalska, I.Shchyhel, A. Horlach
03. CELL AND MOLECULAR BIOLOGY
P.072 CHARACTERIZING 2D AND 3D ORGANOID CULTURES DERIVED FROM MOUSE AND HUMAN PANCREAS SPECIMENS
LIST OF POSTERS
*PD-29
V. Szabó, Á. Varga, J. Maléth
P.073 ROLE OF THE OBESTATIN/GPR39 IN THE SYNTHESIS AND SECRETION OF PANCREATIC ENZYMES
S. Leal-Lopez, L. Estevez-Perez, R. Gallego-Gomez, T. Garcia-Caballero, J. Perez-Camiña, J.E. Dominguez-Muñoz,
Y. Pazos-Randulfe
P.074 TRANSLATOME-BASED CLASSIFICATION REVEALS A DUAL METABOLIC DEPENDENCY OF A NEW TUMOR SUBTYPE
OF PANCREATIC CANCER
S. Shin, R. Nicolle, C. Jean, R. Samain, M. Ayadi, J. Raffenne, A. Brunel, J. Solorzano, C. Neuzillet, C. Joffre, S. Rocchi,
J. Iovanna, N. Dusetti, O. Larsson, S. Pyronnet, C. Bousquet, Y. Martineau
P.075 MODELLING EVOLUTION OF PDAC TOWARDS AGGRESSIVE PHENOTYPES USING THE ORGANOID CULTURE SYSTEM
*PD-08
A. Malinova, A. Franceschini, S. Andreani, S. D’agosto, P. Delfino, E. Sereni, A. Pea, R. Salvia, R.T. Lawlor, B. Rusev,
A. Scarpa, E. Fiorini, V. Corbo
P.076 AGR2 PROMOTES THE GROWTH OF PANCREATIC DUCTAL ADENOCARCINOMA BY STIMULATING CAFS-DERIVED IGF1
SIGNALING IN A PARACRINE MANNER
H. Li, K. Schuck, Z. Zhang, Y. Yu, H. Friess, C.W. Michalski, X. Zou, S. Shen, B. Kong
P.077 INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM DEREGULATED MICRORNAS CONVERGE ON ACTIN CYTOSKELETON-
RELATED PATHWAYS THAT ARE MAINTAINED IN PANCREATIC DUCTAL ADENOCARCINOMA
E. Fernández-Castañer, M. Vila-Casadesús, E. Vila-Navarro, C. Parra, J.J. Lozano, A. Castells, M. Gironella, I. Cos
P.078 ADAPTATION OF PANCREATIC STELLATE CELLS TO OXIDATIVE STRESS EVOKED BY HYPOXIA IS MODULATED
BY MELATONIN
M. Estaras, M. Fernandez-Bermejo, J.M. Mateos, D. Vara, G. Blanco, D. Lopez, V. Roncero, G.M. Salido, A. Gonzalez
P.079 MODULATION OF RNA SPLICING AS A NOVEL STRATEGY AGAINST PANCREATIC CANCER *PD-06
M. Capula, G. Mantini, R. Sciarrillo, B. El Hassouni, I.G.P. Supadmanaba, T. Lagerweij, T. Würdinger, G.J. Peters, G. Jansen,
J. Cloos, E. Giovannetti
P.080 SPLICING MACHINERY DYSREGULATION AND ITS RELATIONSHIP WITH PDAC AGGRESSIVENESS
E. Alors Perez, R. Blázquez-Encinas, A. Mafficini, T. Moreno Montilla, C. Viyuela-Garcia, J.M. Jiménez-Vacas,
J.M. Sánchez-Hidalgo, I. Berbel, J.A. Marín-Sanz, M.E. Sánchez-Fría, C. Luchini, A. Pea, S. Ventura, M.D. Gahete,
Á. Arjona-Sánchez, R.T. Lawlor, R.M. Luque, A. Scarpa, A. Ibáñez-Costa, J.P. Castaño
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P.081 PATHOMORPHOLOGICAL CHANGES IN WALKER-256 CARCINOSARCOMA DUE TO COMBINED CRYOCHEMICAL ABLATION
(EXPERIMENTAL STUDY)
O. Dronov, S. Zemskov, Y. Kozachuk, M. Onischenko
P.082 FUNCTIONAL EFFECTS OF HUMAN PANCREATIC TRYPSIN INHIBITOR (SPINK1) MUTATIONS ON THE MOUSE ORTHOLOGUE
SPINK3 INHIBITOR
N. Morales Granda, A. Szabo
P.083 EPIGENETIC REPROGRAMMING OF CLASSICAL AND BASAL-LIKE PANCREATIC CANCER SUBTYPES
Q. Zhou, S. Pichlmeier, T. Straub, A. Kirmayr, S. Benitz, U.M. Mahajan, L. Fahr, C.W. Michalski, J. Kleeff, J. Mayerle, I. Regel
04. CYSTIC PANCREATIC LESIONS
P.084 EVALUATING SUSPECTED INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS (IPMN) WITH SPYGLASS
PANCREATOSCOPY
S. Vehviläinen, N. Fagerström, R. Valente, H. Seppänen, M. Udd, O. Lindström, H. Mustonen, F. Swahn, U. Arnelo,
L. Kylänpää
P.085 10 YEAR SURVIVAL AND CHARACTERISTICS OF OPERATED IPMNS IN THE FINNISH NATIONWIDE DATABASE
Y. Vaalavuo, A. Antila, R. Ahola, I. Rinta-Kiikka, M. Vornanen, J. Sand, J. Laukkarinen
P.086 EARLY OCCURRENCE OF PSEUDOCYSTS IN ACUTE PANCREATITIS - A MULTICENTER INTERNATIONAL COHORT ANALYSIS
OF 2275 ACUTE PANCREATITIS CASES
L. Szakó, A. Váradi, B. Tinusz, N. Vörhendi, D. Mosztbacher, Á. Vincze, T. Takács, L. Czakó, F. Izbéki, L. Gajdán,
V. Dunás-Varga, J. Hamvas, M. Papp, K.E. Fehér, M. Varga, A. Mickevicius, I. Török, K. Ocskay, M.F. Juhász, S. Váncsa,
LIST OF POSTERS
N. Faluhelyi, O. Farkas, A. Miseta, A. Vereczkei, A. Mikó, P.J. Hegyi, A. Szentesi, A. Párniczky, B. Eross, P. Hegyi
P.087 INTRACYSTIC GLUCOSE IS MORE ACCURATE THAN CARCINOEMBRYONIC ANTIGEN FOR THE DIAGNOSIS OF MUCINOUS
PANCREATIC CYSTIC LESIONS: A META-ANALYSIS
G. Capurso, G. Rossi, M.C. Petrone, P.G. Arcidiacono
P.088 CYSTIC LESIONS OF THE PANCREAS: HOW ACCURATE IS THE PREOPERATIVE DIAGNOSIS?
J. Nijhuis, M. Liem, G. Patijn, F. Wit, E. Duiker, M. van den Heuvel, J. Klaase
P.089 REMODELING OF THE PANCREAS IN PANCREATITIS AND CYST FORMATION
I. Kryvoruchko, V. Boyko, Y. Ivanova
P.090 A PANCREATIC CYSTIC NEOPLASMS DRAMA. ACCURACY OF DIAGNOSTIC PRESUMPTION AND SURGICAL INDICATION
ON A TEN-YEAR EXPERIENCE
F. Giannone, S. Crippa, G. Belfiori, S. Partelli, D. Tamburrino, N. Pecorelli, E. Longo, M. Schiavo Lena, D. Palumbo,
P.G. Arcidiacono, M. Falconi
P.091 MIRNA BIOMARKER CANDIDATES IN PANCREATIC CYSTIC FLUIDS *PD-16
C. Driescher, L. Haeberle, W. Goering, T. Wachtmeister, F.V. Opitz, H.-K. Preissinger-Heinzel, W. Hartwig, T. Beyna,
H. Neuhaus, W.T. Knoefel, V. Keitel, T. Lüdde, I. Esposito
P.092 DIFFUSE PANCREATIC SEROUS CYSTIC NEOPLASM: A RARE CAUSE OF PANCREATIC INSUFFICIENCY
M.C. Conti Bellocchi, M. Cattani Mottes, S. Crino’, A. Amodio, L. Frulloni
P.093 SURGERY FOR IPMN OF THE PANCREAS: PREOPERATIVE FACTORS TIPPING THE SCALE OF THE DECISION MAKING.
A BICENTRIC ANALYSIS
A. Caravati, G. Marchegiani, G. Perri, S. Andrianello, T. Pollini, T. Dall’Olio, G. Belfiori, S. Crippa, S. Partelli, E. Longo,
M. Falconi, R. Salvia, C. Bassi
P.094 SYSTEMATIC REVIEW AND META-ANALYSIS OF OBSERVATIONAL STUDIES ON BD-IPMN PROGRESSION TO MALIGNANCY
A. Balduzzi, G. Marchegiani, M. Biancotto, S. Andrianello, T. Pollini, A. Caravati, R. Salvia, C. Bassi
P.095 GUIDELINES ON PANCREATIC CYSTIC NEOPLASMS: MAJOR INCONSISTENCIES WITH AVAILABLE EVIDENCE AND CLINICAL
PRACTICE
A. Balduzzi, G. Marchegiani, S. Andrianello, T. Pollini, A. Caravati, M. Biancotto, D. Bonamini, E. Secchettin, C. Bassi,
H. Friess, R. Salvia
P.096 ICYST: 1 YEAR, 1000 AND MORE SIMULATIONS THROUGH AN APP
A. Balduzzi, G. Marchegiani, S. Andrianello, T. Pollini, A. Caravati, M. Biancotto, D. Bonamini, E. Secchettin, C. Bassi,
H. Friess, R. Salvia
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P.097 MANAGEMENT OF IPMNS WITH WORRISOME FEATURES: A CLINICAL DILEMMA
F. Aleotti, T. Pessarelli, G. Belfiori, S. Crippa, M.C. Petrone, E. Longo, D. Tamburrino, S. Partelli, G. Rossi, G. Capurso,
P.G. Arcidiacono, M. Falconi
P.098 MALIGNANCY RISK OF BD-IPMN BEYOND 5 YEAR OBSERVATION
E.M. Fuchs, C. Jäger, B. Kong, I.E. Demir
05. DIABETES AND EXOCRINE / ENDOCRINE INTERACTION
P.099 CARBOHYDRATE INTOLERANCE AND DIABETES IN CHILDREN WITH PANCREATITIS
A. Mianowska, M. Rakowska, G. Oracz, K. Kretkowska
P.100 PREOPERATIVE DIABETES MELLITUS IN PATIENTS UNDERGOING PANCREATIC SURGERY *PD-30
M. Stott, B. Crosby, L. Oldfield, R. Rao, C.M. Halloran, E. Costello
P.101 EVALUATION OF CURRENTLY AVAILABLE SCREENING METHODS FOR CYSTIC FIBROSIS-RELATED DIABETES *PD-25
V. Izsak, A. Soos, Z. Szakacs, P. Hegyi, O. Varannai, A.R. Martonosi, F.M. Juhasz, M. Foldi, A. Kozma, Z. Vajda, J.A. Shaw,
A. Parniczky
P.102 SECRETORY ACTIVITY OF PANCREATIC DUCTAL EPITHELIAL CELLS IS INCREASED IN MICE WITH INDUCED DIABETES
A. Ébert, E. Tóth, E. Gál, P. Hegyi, V. Venglovecz
P.103 SEVERE ASYMPTOMATIC HYPERTRIGLYCERIDEMIA PROMOTED BY UNCONTROLLED FRUCTOSE INGESTION IN NEWLY
DIAGNOSED TYPE 2 DIABETES TREATED WITH PLASMAPHERESIS
LIST OF POSTERS
A. Dugic, M. Kryk, C. Braig, J. Kothmann, S. Petermann, S. Mühldorfer
P.104 ENDOCRINE AND EXOCRINE INSUFFICIENCY AFTER DISTAL PANCREATECTOMY, A META-ANALYSIS
D.-J. Yang, W.M. Hu
06. ENDOSCOPY
P.105 ROLE OF FLUORESCENCE CONFOCAL MICROSCOPY FOR RAPID EVALUATION OF ENDOSCOPIC ULTRASOUND FINE NEEDLE
BIOPSY IN PANCREATIC SOLID LESIONS
S. Stigliano, D. Biasutto, F.M. Di Matteo
P.106 WITHDRAWN
P.107 PERFORMANCE OF EUS-FNB IN SOLID PANCREATIC MASSES: A LESSON FROM 463 CONSECUTIVE PROCEDURES
AND A PRACTICAL NOMOGRAM
C. Ingaldi, N. Pagano, C. Ricci, L. Alberici, S. Saddalla, M. Zagari, A. De Leo, M. Cescon, R. Casadei
P.108 EFFICACY OF EUS-GUIDED FINE NEEDLE BIOPSY (EUS-FNB) WITH CORE NEEDLES FOR THE HISTOLOGICAL DIAGNOSIS
OF SOLID PANCREATIC LESIONS (SPL)
J. Iglesias-Garcia, J. Lariño-Noia, D. De La Iglesia-Garcia, I. Abdulkader-Nallib, H. Lazare, J.E. Dominguez-Muñoz
P.109 ACCURACY OF EUS-GUIDED ELASTOGRAPHY (EUS-E) TO CONFIRM MALIGNANCY IN PATIENTS WITH RESECTABLE SOLID
PANCREATIC LESIONS (SPL)
J. Iglesias-Garcia, J. Lariño-Noia, D. De La Iglesia-Garcia, J.E. Dominguez-Muñoz
P.110 ENDOSCOPIC PAPILLECTOMY VS. PANCREATICODUODENECTOMY FOR AMPULLARY LESIONS: A PROPENSITY-SCORED
MATCHING ANALYSIS OF THE ESAP STUDY
M. Hollenbach, C. Heise, E.A. Ali, F. Auriemma, A. Gulla, S. Regner, S. Gaujoux
P.111 THE ROLE OF ENDOSCOPIC ULTRASOUND (EUS) IN THE DIAGNOSIS AND TREATMENT OF INSULINOMA: A SYSTEMATIC
REVIEW OF THE LITERATURE
G. El-Sayed, L. Frim, J. Franklin, R. McCrudden, C. Gordon, S. Al-Shamma, S. Kiss, P. Hegyi, B. Eross, P.J. Hegyi
P.112 LUMEN APPOSING METAL STENTS: HOW FAR ARE WE FROM STANDARDIZATION? AN ITALIAN SURVEY
C. Fabbri, C. Coluccio, C. Binda, A. Fugazza, A. Anderloni, I. Tarantino, I-EUS Group
P.113 WITHDRAWN
P.114 WITHDRAWN
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